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2017

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Articles 62431 - 62460 of 62840

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The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun Jan 2017

The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun

Turkish Journal of Medical Sciences

Background/aim: Clinicians associate the changes in cervical lordosis with neck pain, but there is no clear consensus on this. We aimed to investigate the relationships of cervical angles, neck pain, disability, and the psychological status of the patients with acute and chronic neck pain. Materials and methods: A total of 110 patients with neck pain were included in this study. Demographic and clinical characteristics of the patients were recorded. The lordosis angle was determined by the posterior tangent method. A visual analog scale (VAS), the Neck Disability Index (NDI), and the Hospital Anxiety and Depression (HAD) scale were administered to …

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Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur Jan 2017

Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the epidemiologic characteristics, the causative microorganisms and their antimicrobial susceptibility patterns, and the prognostic risk factors for mortality in critically ill patients with ventilator-associated pneumonia (VAP). Materials and methods: In this retrospective observational study, all the critically ill patients with VAP hospitalized in a medical/surgical intensive care unit (ICU) between January 2010 and June 2015 were evaluated. Patients' demographic features and microbiological data were reviewed. Results: A total of 417 patients were clinically diagnosed with VAP; 51.1% of them were male and the average age was found as 69.9 ± 15.9 …

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Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay Jan 2017

Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay

Turkish Journal of Medical Sciences

Background/aim: Understanding the causes of under-five deaths is key to realizing sustainable developmental goals. The aim of this descriptive study was to investigate the causes of under-five mortality in İstanbul during 2011 and compare the findings to those of 1988 and 2000. Materials and methods: All burial records of İstanbul were evaluated, and cemetery records of 1494 children, who died at under five years of age and were buried in İstanbul Metropolitan Municipality Cemeteries between 1 January and 31 December 2011, were analyzed. Several sociodemographic characteristics and causes of death were compared with the results of studies carried out in …

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Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan Jan 2017

Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan

Turkish Journal of Medical Sciences

Background/aim: Diabetic foot ulcers and related complications are a major cause of morbidity and hospital admissions. Our aim was to evaluate the risk factors associated with poor outcome in diabetic foot ulcers. Materials and methods: A prospective study was conducted on patients with diabetic foot ulceration attending the Madinah Teaching Hospital from June 2014 to December 2015. Potential risk factors and laboratory test results at presentation were recorded and their association with outcome (healing vs. amputation) was analyzed using IBM SPSS Statistics for Windows, Version 22.0. Results: In total, 112 patients were studied during our study period. The majority of …

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Impact Of Adjuvant Treatment On Oncologic Outcomes Inpatients With Stage I Leiomyosarcoma Of The Uterus, Gökhan Boyraz, Derman Başaran, Mehmet Coşkun Salman, Nejat Özgül, Kunter Yüce Jan 2017

Impact Of Adjuvant Treatment On Oncologic Outcomes Inpatients With Stage I Leiomyosarcoma Of The Uterus, Gökhan Boyraz, Derman Başaran, Mehmet Coşkun Salman, Nejat Özgül, Kunter Yüce

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the role of adjuvant therapy for stage I uterine leiomyosarcoma (LMS). Materials and methods: Clinicopathological data of cases of stage I uterine LMS from 1998 to 2015 were retrieved from the computerized database of Hacettepe University Hospital. The Kaplan-Meier method was used to estimate survival and progression-free survival, and survival differences were analyzed by log-rank test. Cox regression analysis was performed to account for the potential influence of confounding factors. Results: We evaluated the outcomes of 35 patients with histologically proven stage I LMS. The median age at diagnosis was 50 years. All patients …

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Frequency Of Human Parvovirus 4 (Parv4) Viremia Among Hbv-Infected Patients And Healthy Donors In Shiraz, Iran, Fereshte Amirahmadi, Jamal Sarvari, Seyed Younes Hosseini, Neda Pirbonyeh, Ali Akbar Gorzin Jan 2017

Frequency Of Human Parvovirus 4 (Parv4) Viremia Among Hbv-Infected Patients And Healthy Donors In Shiraz, Iran, Fereshte Amirahmadi, Jamal Sarvari, Seyed Younes Hosseini, Neda Pirbonyeh, Ali Akbar Gorzin

Turkish Journal of Medical Sciences

Background/aim: PARV4, a small DNA virus belonging to the family Parvoviridae, was first isolated in an HBV injecting drug user. Several studies have investigated PARV4 co-infection with HBV and HCV and its effect on the progression of liver disease. The aim of this study was to determine the frequency of PARV4 among HBV-infected patients and healthy individuals. Materials and methods: A group of 90 HBV patients and a group of 90 healthy subjects were included in this study. Samples were selected after screening tests such as HBsAg ELISA, anti-HCV ELISA, and anti-HIV ELISA. Nested-PCRs were conducted to detect the PARV4 …

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Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps, Hakan Uzun, Ozan Bi̇ti̇k, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu Jan 2017

Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps, Hakan Uzun, Ozan Bi̇ti̇k, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu

Turkish Journal of Medical Sciences

Background/aim: Resection of tumors from the groin and thigh regions with safe margins often results in significant soft tissue defects, which preclude primary closure. This study presents a series of rectus abdominis myocutaneous flaps for irradiated thigh and groin wounds with the purpose of evaluating the efficacy and outcomes of these flaps in this population. Materials and methods: From 2008 to 2015, all patients who underwent resection of thigh or groin region tumors and reconstruction with an inferiorly based rectus abdominis myocutaneous flap were retrospectively identified. Medical records of the patients were reviewed. Results: A total of 27 patients, aged …

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Routine Assessment Of Occupational Exposure And Its Relation To Semen Quality In Infertile Men: A Cross-Sectional Study, Salima Daoud, Afifa Sellami, Mehdi Bouassida, Sahbi Kebaili, Leila Ammar Keskes, Tarek Rebai, Nozha Chakroun Feki Jan 2017

Routine Assessment Of Occupational Exposure And Its Relation To Semen Quality In Infertile Men: A Cross-Sectional Study, Salima Daoud, Afifa Sellami, Mehdi Bouassida, Sahbi Kebaili, Leila Ammar Keskes, Tarek Rebai, Nozha Chakroun Feki

Turkish Journal of Medical Sciences

Background/aim: Concerns about the detrimental effects of occupational and environmental exposure on male reproductive function have been raised by reports of declining sperm quality over the last decades. The aim of this study was to investigate the association between altered semen parameters and exposure to occupational risk factors as assessed by questionnaire. Materials and methods: We conducted a cross-sectional questionnaire-based study among a population of 2122 men who underwent andrological investigation for couple infertility. All participants were interviewed and their semen samples were analyzed. Information about medical history and occupational exposure was used to classify participants into exposed and unexposed …

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Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal Jan 2017

Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal

Turkish Journal of Medical Sciences

Background/aim: Helicobacter pylori is a pathogen that colonizes a majority of the world's population. Genetic diversity within the virulence genes of bacteria such as cagPAI and vacA may have a modified effect on the pathogenic potential of the bacteria. This study aimed to investigate which genes can be suggested as potentially related virulence factors for H. pylori-associated active chronic gastritis and stomach adenocarcinoma in the northwest of Iran and south of Turkey. Materials and methods: Formalin-fixed, paraffin-embedded stomach biopsy tissue samples were obtained from Iranian and Turkish patients from selected geographical regions. The prevalence of selected cagPAI genes and vacA …

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Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay Jan 2017

Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay

Turkish Journal of Medical Sciences

Background/aim: Increased airway resistance reduces the effectiveness of ventilation treatment. Endotracheal tubes (ETTs) and connectors contribute to resistance. However, the effect of a closed system suction (CSS) connector is not well known. We compared the in vivo resistance occurring with a CSS connector with that of the standard connector. Materials and methods: This prospective study was conducted at Gazi University Hospital's neonatal intensive care unit. Intubated neonates were studied for two cycles; each cycle contained two periods of ETT + connector pairs (15 min/period) as follows: cycle 1 [A: long ETT + standard connector; B: long ETT + CSS connector] …

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Male Infertility Is Significantly Associated With Multiple Deletions In An 8.7-Kb Segment Of Sperm Mtdna In Pakistan, Irfan Afzal Mughal, Asma Irfan, Sarwat Jahan, Abdul Hameed Jan 2017

Male Infertility Is Significantly Associated With Multiple Deletions In An 8.7-Kb Segment Of Sperm Mtdna In Pakistan, Irfan Afzal Mughal, Asma Irfan, Sarwat Jahan, Abdul Hameed

Turkish Journal of Medical Sciences

Background/aim: This study aimed to find a link between sperm mitochondrial DNA mutations and male infertility in Pakistan. Materials and methods: DNA from semen samples was extracted and amplified by PCR using 7.8-kb deletion-specific primers. The PCR products were separated on agarose gel, visualized under UV-illumination, and then photographed. The results were genotyped and the data were analyzed using SPSS. Results: Deletion analysis of the 8.7-kb fragment by long PCR revealed multiple deletions. The frequency of deletion was much higher in infertile groups as compared to the control group. Further, on comparison between different subtypes of infertile groups, the deletions …

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Serum Ischemic Modified Albumin (Ima) Concentration And Ima/Albumin Ratio In Patients With Hepatitis B-Related Chronic Liver Diseases, Fatma Yavuz, Murat Biyik, Mehmet Asil, Ramazan Dertli̇, Ali̇ Demi̇r, Hakki Polat, Sali̇ha Uysal, Hüseyi̇n Ataseven Jan 2017

Serum Ischemic Modified Albumin (Ima) Concentration And Ima/Albumin Ratio In Patients With Hepatitis B-Related Chronic Liver Diseases, Fatma Yavuz, Murat Biyik, Mehmet Asil, Ramazan Dertli̇, Ali̇ Demi̇r, Hakki Polat, Sali̇ha Uysal, Hüseyi̇n Ataseven

Turkish Journal of Medical Sciences

Background/aim: Albumin is the most important protein synthesized by the liver. Posttranscriptional changes occur in the molecular structure of albumin due to various factors and isoforms arise. Ischemic modified albumin (IMA) is one such isoform. This study was conducted to evaluate serum IMA concentrations in patients with hepatitis B virus (HBV)-related chronic liver diseases. Materials and methods: This study included 74 treatment-naive chronic hepatitis B patients, 25 patients with HBV-related cirrhosis, and 49 healthy controls. Serum IMA concentration was measured spectrophotometrically using the albumin cobalt binding test. Results: The mean IMA concentrations in the chronic hepatitis B group and healthy …

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Morphometric Study Of The True S1 And S2 Of The Normal Anddysmorphic Sacralized Sacra, Ayşegül Firat, Kadi̇r Bahadir Alemdaroğlu, Ahmet Özmeri̇ç, Mehmet Yücens, Di̇nçer Göksülük Jan 2017

Morphometric Study Of The True S1 And S2 Of The Normal Anddysmorphic Sacralized Sacra, Ayşegül Firat, Kadi̇r Bahadir Alemdaroğlu, Ahmet Özmeri̇ç, Mehmet Yücens, Di̇nçer Göksülük

Turkish Journal of Medical Sciences

Background/aim: This study aimed to generate data for the S1 and S2 alar pedicle and body and the alar orientations for both dysmorphic and normal sacra. Materials and methods: The study comprised two groups: Group N consisted of 53 normal sacra and Group D included 10 dysmorphic sacra. Various features such as alar pedicle circumference; anterior, middle, and posterior axis of the sacral ala; sacral body height and width; and sagittal thickness were measured. Results: In group N, the median anterior axis of the alae was observed to be 30° on the right and 25° on the left, the median …

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The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k Jan 2017

The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Acetylsalicylic acid (ASA) treatment in diabetic patients is very important owing to the increasing hyperactivity of thrombocytes and atherosclerosis. In several investigations, it was reported that diabetes caused increased coronary artery disease, cerebrovascular disease, and death. In this study, we aimed to investigate the effect of ASA on osmoregulation, glycemic control, and some biochemical parameters in rats induced with experimental diabetes type 2. Materials and methods: Twenty-four rats were randomly divided in four groups: control (I), ASA control (II), diabetic (III), and ASA diabetic (IV). Diabetes was induced by streptozotocin treatment (30 mg/kg, twice, intraperitoneal injection) in obese rats. …

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Changes In The Serum, Liver, And Renal Cortical Lipids And Electrolytesin Rabbits With Cisplatin-Induced Nephrotoxicity, Abdelgayoum Ahmed Abdel-Gayoum, Mohamed Hamza Sulaiman Ahmida Jan 2017

Changes In The Serum, Liver, And Renal Cortical Lipids And Electrolytesin Rabbits With Cisplatin-Induced Nephrotoxicity, Abdelgayoum Ahmed Abdel-Gayoum, Mohamed Hamza Sulaiman Ahmida

Turkish Journal of Medical Sciences

Background/aim: Cisplatin is an anticancer drug that can induce nephrotoxicity. Its toxicity is associated with dyslipidemia and disturbed electrolyte balance. In the present study we investigated the changes in serum lipid profile and electrolyte levels and their contents in kidney and liver tissues of rabbits treated with cisplatin. Materials and methods: Twenty-eight adult male New Zealand White rabbits were used in the experiment. Animals of groups C, P1, and P2 were injected with saline, cisplatin (4.0 mg/kg bw), and cisplatin (6.5 mg/kg bw), respectively, and killed 3 days after the injections. Animals of group R were given cisplatin (6.5 mg/kg …

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Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca Jan 2017

Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca

Turkish Journal of Medical Sciences

Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on collagen-induced arthritis (CIA). Materials and methods: Arthritis was induced by the intradermal injection of chicken type II collagen with incomplete Freund's adjuvant into albino Wistar rats. Doses of 5 and 20 mg/kg GEM were administered twice a week after the 14th day, which marked the onset the arthritis. Serum IL-17, TNF-α, malondialdehyde, catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels and tissue heme oxygenase-1 (HO-1) and nuclear factor …

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Comparison Of Endothelin And Nitric Oxide Synthase Blockerson Hemorheological Parameters In Endotoxemic Rats, Nesli̇han Hacer Di̇kmenoğlu Falkmarken, Okan Arihan, Alper Bektaş İski̇t Jan 2017

Comparison Of Endothelin And Nitric Oxide Synthase Blockerson Hemorheological Parameters In Endotoxemic Rats, Nesli̇han Hacer Di̇kmenoğlu Falkmarken, Okan Arihan, Alper Bektaş İski̇t

Turkish Journal of Medical Sciences

Background/aim: Septic shock is an important health problem that vastly alters cardiovascular and hemodynamic status. Increased production of nitric oxide (NO) and endothelin is a counterpart of this endotoxemic state. This study was conducted to test the hypothesis that nonselective NO synthesis blocker (L-NAME), inducible NO synthesis blocker (L-canavanine), or endothelin receptor antagonist (bosentan) will reverse the effects of sepsis on hemorheological parameters. Materials and methods: Forty-eight male Sprague-Dawley rats were used in 8 groups: saline (control), endotoxin, bosentan, L-NAME, L-canavanine, endotoxin + bosentan, endotoxin + L-NAME, and endotoxin + L-canavanine. Blood was withdrawn at the 4th hour of endotoxemic …

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Chemokine Cxcr-4 And Cyclooxygenase-2 In The Pathogenesis Of Pterygium, Gönen Başer, Oya Nermi̇n Si̇vri̇koz, Eyyüp Karahan, Emi̇ne Şeker Ün, Hakan Yildirim, Sülen Sarioğlu Jan 2017

Chemokine Cxcr-4 And Cyclooxygenase-2 In The Pathogenesis Of Pterygium, Gönen Başer, Oya Nermi̇n Si̇vri̇koz, Eyyüp Karahan, Emi̇ne Şeker Ün, Hakan Yildirim, Sülen Sarioğlu

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the expression of chemokine receptor 4 (CXCR-4) and cyclooxygenase-2 (COX-2) in the epithelium and stroma of pterygium tissue in comparison with healthy conjunctiva. Materials and methods: The expression of CXCR4 and COX-2 was investigated by immunohistochemistry in the epithelium and stroma of the pterygium tissue of 29 eyes and compared with healthy conjunctival tissues. The correlation between CXCR4 and COX-2 expression as well as the correlation of these markers with the area of pterygium were evaluated statistically. Results: COX-2 staining scores were 1.75 ± 0.63 in the epithelium and 1.20 ± 0.62 in the …

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Relationship Of Peripheral Blood Neutrophil To Lymphocyteratio And Irritable Bowel Syndrome, Mustafa Güçlü, Ahmet Faruk Ağan Jan 2017

Relationship Of Peripheral Blood Neutrophil To Lymphocyteratio And Irritable Bowel Syndrome, Mustafa Güçlü, Ahmet Faruk Ağan

Turkish Journal of Medical Sciences

Background/aim: This study aimed to determine the relationship between the peripheral blood neutrophil to lymphocyte ratio (NLR) and irritable bowel syndrome (IBS). Materials and methods: A total of 107 patients suffering from constipation-predominant IBS, diagnosed in accordance with the ROMA III criteria and having complete blood count tests, were enrolled in this study. All patients underwent total colonoscopy in order to rule out any probable underlying organic colonic pathology. Results: The control group consisted of 106 healthy people with no medical complaints. The peripheral blood NLR was 2.80 ± 2.52 on average in the IBS group. The NLR average was …

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Cartilage Reinforcement Graft Versus Fascia Graft In Tympanoplasty, Emre Ocak, Süha Beton, Vedat Taş, Cem Meço Jan 2017

Cartilage Reinforcement Graft Versus Fascia Graft In Tympanoplasty, Emre Ocak, Süha Beton, Vedat Taş, Cem Meço

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to compare cartilage reinforcement graft results with temporalis fascia graft alone in terms of hearing and anatomical outcomes in tympanoplasty. Materials and methods: Patients who underwent tympanoplasty with/without ossiculoplasty and/or mastoidectomy at a university hospital from 2006 through 2013 were reviewed retrospectively. The patients were divided into those grafted with temporalis muscle fascia alone and with fascia reinforced with cartilage. The postoperative air bone gap, gain in hearing thresholds, and graft status were evaluated for each group. Results: The study subjects included 179 patients. There were 82 patients in the fascia group and …

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Endovascular Embolization In The Management Of Traumatic Andpostoperative Abdominopelvic Bleeding: A Single-Center Experience, Di̇lek Sağlam, Hasan Di̇nç, Abdulkadi̇r Gündüz, Ayşegül Cansu, Mehmet Hali̇l Öztürk Jan 2017

Endovascular Embolization In The Management Of Traumatic Andpostoperative Abdominopelvic Bleeding: A Single-Center Experience, Di̇lek Sağlam, Hasan Di̇nç, Abdulkadi̇r Gündüz, Ayşegül Cansu, Mehmet Hali̇l Öztürk

Turkish Journal of Medical Sciences

Background/aim: Endovascular embolization is widely used instead of surgery in the treatment of traumatic and postoperative abdominopelvic bleeding. The objective of this study is to evaluate the efficiency of computed tomography in the determination of active bleeding and the efficiency of endovascular embolization in traumatic and postoperative abdominopelvic bleeding. Materials and methods: Thirty-one patients admitted to our hospital with traumatic and postoperative abdominopelvic bleeding between January 2006 and September 2012 and treated with endovascular embolization were retrospectively enrolled in the study. In 15 hemodynamically stable patients, abdominal computed tomography was performed to detect the presence and/or localization of the hemorrhage. …

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The Prevalence Of Abdominal Obesity Is Remarkable For Underweightand Normal Weight Adolescent Girls, Ni̇lüfer Tek, Nevi̇n Şanlier, Duygu Türközü Jan 2017

The Prevalence Of Abdominal Obesity Is Remarkable For Underweightand Normal Weight Adolescent Girls, Ni̇lüfer Tek, Nevi̇n Şanlier, Duygu Türközü

Turkish Journal of Medical Sciences

Background/aim: Obesity is a global public health challenge. This study was carried out in order to determine the prevalence of obesity and abdominal obesity in Turkish adolescent girls. Materials and methods: A cross-sectional study was conducted in a total of 1111 adolescent girls aged 12?18 years. The subjects were classified into four groups: underweight, normal, overweight, and obese. Abdominal obesity was defined according to waist circumference (WC) $\geq$ 90th percentile for Turkish adolescent population references (12-17 years) and waist-to-height ratio (WHtR) $\geq$ 0.5. Results: The prevalence of underweight was 17.4%, normal weight 68.5%, overweight 12.1%, and obese 2.0%. A total …

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Evaluation Of Lipid Profiles In Patients Treated With Capecitabine, Nursel Sürmeli̇oğlu, Semra Paydaş, Yusuf Karataş, Gülşah Seydaoğlu Jan 2017

Evaluation Of Lipid Profiles In Patients Treated With Capecitabine, Nursel Sürmeli̇oğlu, Semra Paydaş, Yusuf Karataş, Gülşah Seydaoğlu

Turkish Journal of Medical Sciences

Background/aim: Capecitabine is a prodrug of 5-fluorouracil and has shown significant antitumor activity. The main adverse effects are hand-foot syndrome, diarrhea, and dermatitis. In recent years, hypertriglyceridemia has been reported in patients treated with capecitabine. Dyslipidemia is a rare but important side effect of capecitabine. The aim of this study is to examine the changes in lipid levels during capecitabine treatment and to raise awareness of pharmacovigilance. Materials and methods: In this retrospective study, it was aimed to analyze lipid metabolism after capecitabine treatment and is intended to contribute to the formation of a pharmacoepidemiological database. For this purpose, triglyceride, …

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Prevention Of Propofol Injection-Related Pain Using Pretreatment Transcutaneous Electrical Acupoint Stimulation, Luping Huang, Yuanyuan Pan, Sijia Chen, Minyuan Zhang, Xiuxiu Zhuang, Shenhui Jin, Junlu Wang, Qinxue Dai, Yunchang Mo Jan 2017

Prevention Of Propofol Injection-Related Pain Using Pretreatment Transcutaneous Electrical Acupoint Stimulation, Luping Huang, Yuanyuan Pan, Sijia Chen, Minyuan Zhang, Xiuxiu Zhuang, Shenhui Jin, Junlu Wang, Qinxue Dai, Yunchang Mo

Turkish Journal of Medical Sciences

Background/aim: This study aimed to study the effect of pretreatment transcutaneous electrical acupoint stimulation (TEAS) in preventing propofol injection-related pain. Materials and methods: A total of 360 patients who were to undergo elective hysteroscopy surgery were randomly divided into the following three groups of 120 patients each: control (Group C), sham TEAS (Group F), and TEAS (Group T). Patients in Group C did not undergo any treatment before surgery; 30 min before the induction of anesthesia, patients in Groups F and T underwent electrical stimulation of the bilateral LI4-PC6 acupoint. Patients in Group F were subjected to 'feeling flow', while …

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Sex-Related Differences In The Efficacy Of Dexamethasone Pretreatmentfor Postoperative Analgesia In Patients Undergoing Laparoscopiccholecystectomy: A Randomized Controlled Study, Choel Lee, Jae-Yoon Chung, Myeongjong Lee Jan 2017

Sex-Related Differences In The Efficacy Of Dexamethasone Pretreatmentfor Postoperative Analgesia In Patients Undergoing Laparoscopiccholecystectomy: A Randomized Controlled Study, Choel Lee, Jae-Yoon Chung, Myeongjong Lee

Turkish Journal of Medical Sciences

Background/aim: Sex-related differences in response to pain have become a topic of increasing interest. However, sex-related differences in the efficacy of dexamethasone for postoperative analgesia have not been previously addressed. Materials and methods: The study included 196 men and 196 women, aged between 18 and 45 years, who were scheduled for laparoscopic cholecystectomy. The patients were randomly allocated into dexamethasone (M/F: 98/98) and control (normal saline; M/F: 98/98) groups. Patients in the study group received intravenous dexamethasone at 0.1 mg/kg (dexamethasone group) 1 h before induction of anesthesia. Patients in the control group received normal saline. Changes in cumulative morphine-containing, …

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The Comparison Of Various Disinfectants? Efficacy On Staphylococcus Aureus And Pseudomonas Aeruginosa Biofilm Layers, Hati̇ce Köse, Nur Yapar Jan 2017

The Comparison Of Various Disinfectants? Efficacy On Staphylococcus Aureus And Pseudomonas Aeruginosa Biofilm Layers, Hati̇ce Köse, Nur Yapar

Turkish Journal of Medical Sciences

Background/aim: Because biofilms are resistant to antibiotics and biocides, they usually cause chronic persistent infections, which are arduous to cure and have high mortality and morbidity. Our study aimed to investigate the efficiency of orthophthalaldehyde, peracetic acid, hydrogen peroxide, and sodium hypochlorite on Pseudomonas aeruginosa and Staphylococcus aureus biofilm layers and live microbial cells. Materials and methods: Biofilm layers were determined by crystal violet assay and live microbial cells were determined using a resazurin assay. Results: For Pseudomonas aeruginosa, sodium hypochlorite showed the most influential disinfection because it diminished 83.6% of the biofilm layer and decreased 99.7% of live microbial …

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Relationship Between Kinesiophobia And Pain, Quality Of Life, Functional Status, Disease Activity, Mobility, And Depression In Patients With Ankylosing Spondylitis, Deran Oskay, Zeynep Tuna, İrem Düzgün, Bülent Elbasan, Yavuz Yakut, Abdurrahman Tufan Jan 2017

Relationship Between Kinesiophobia And Pain, Quality Of Life, Functional Status, Disease Activity, Mobility, And Depression In Patients With Ankylosing Spondylitis, Deran Oskay, Zeynep Tuna, İrem Düzgün, Bülent Elbasan, Yavuz Yakut, Abdurrahman Tufan

Turkish Journal of Medical Sciences

Background/aim: Our aim was to investigate the association of kinesiophobia with pain, quality of life, clinical measures, and depression in patients with ankylosing spondylitis (AS). Materials and methods: Patients with AS (n: 163) were enrolled in the study. Kinesiophobia was evaluated with the Tampa Scale of Kinesiophobia (TSK), pain with a visual analog scale (VAS), mobility with Bath Ankylosing Spondylitis Metrology Index (BASMI), disease activity with the Bath AS Disease Activity Index (BASDAI), functional status with the Bath AS Functional Index (BASFI), depression level with Beck's Depression Inventory (BDI), and quality of life with the AS Quality of Life Questionnaire …

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Egfr, Kras, And Braf Mutational Profiles Of Female Patients With Micropapillary Predominant Invasive Lung Adenocarcinoma, Funda Demi̇rağ, Aydin Yilmaz, Ni̇lgün Yilmaz Demi̇rci̇, Ülkü Yilmaz, Yurdanur Erdoğan Jan 2017

Egfr, Kras, And Braf Mutational Profiles Of Female Patients With Micropapillary Predominant Invasive Lung Adenocarcinoma, Funda Demi̇rağ, Aydin Yilmaz, Ni̇lgün Yilmaz Demi̇rci̇, Ülkü Yilmaz, Yurdanur Erdoğan

Turkish Journal of Medical Sciences

Background/aim: This study aimed to analyze EGFR, KRAS, and BRAF mutations in females with micropapillary predominant invasive lung adenocarcinoma and their relationships with immunohistochemical and clinicopathological patterns.Materials and methods: A total of 15 females with micropapillary lung adenocarcinoma were selected. Mutational analysis of the EGFR, KRAS, and BRAF genes was carried out. Information regarding the demographic data, tumor size, treatment, and survival time for each patient was collated, and the predominant cell type, secondary architectural growth patterns, psammoma bodies, necrosis, and visceral pleural and angiolymphatic invasions were evaluated.Results: We identified EGFR mutation in six cases, KRAS mutation in three cases, …

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Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap Jan 2017

Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap

Turkish Journal of Medical Sciences

Background/aim: Colorectal adenomatous polyps are precursors of colorectal cancer (CRC), which can be prevented with surveillance colonoscopy. This study aimed to assess risk factors for the recurrence of colorectal polyps and CRC following polypectomy. Materials and methods: In this single-center trial, a total of 510 patients who applied to the endoscopy unit of Hacettepe University Hospital for various reasons and who were diagnosed with at least one colorectal adenomatous polyp between 2000 and 2010 were retrospectively analyzed. Patients with colorectal adenomatous polyps or CRC recurrences were examined in terms of clinical and histological risk factors. Results: A total of 190 …

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Unknown Vascular Compression Of The Airway In Patients With Congenitalheart Disease And Persistent Lower Respiratory Symptoms, Tuğba Şi̇şmanlar Eyüboğlu, Ayşe Tana Aslan, Çi̇ğdem Öztunali, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Serdar Kula, Betül Emi̇ne Deri̇nkuyu, Öznur Leman Boyunaga Jan 2017

Unknown Vascular Compression Of The Airway In Patients With Congenitalheart Disease And Persistent Lower Respiratory Symptoms, Tuğba Şi̇şmanlar Eyüboğlu, Ayşe Tana Aslan, Çi̇ğdem Öztunali, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Serdar Kula, Betül Emi̇ne Deri̇nkuyu, Öznur Leman Boyunaga

Turkish Journal of Medical Sciences

Background/aim: Airway compression (AC) by vascular structures is an important complication of congenital heart disease (CHD) that often goes unrecognized. It is not easy to identify whether CHD patients require additional invasive examinations or not. Therefore, the present study aims to develop an AC diagnostic algorithm for CHD patients. Materials and methods: CHD patients with persistent respiratory symptoms that were treated between January 2007 and December 2015 were retrospectively reviewed. The following data were recorded for all CHD patients with AC: age, cardiac anomalies, the compressed structure, the airway diameter ratio (ADR), the compressing structure(s), treatment, and follow-up.Results: During the …

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