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Principles Of Physics I Lab (Clayton), Tatiana Krivosheev, Caroline Sheppard, Patricia Todebush, Bram Boroson, Justin Mays

Physics and Astronomy Grants Collections

This Grants Collection for Principles of Physics I was created under a Round Three ALG Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

Oil Painting, A Practice Of Mind And Body, Petros Nagakos

MFA in Visual Arts Theses

How does painting situate itself as an act of resistance to our visual bombardment of the human body, which is primarily transmitted through digital media? This paper explores the possibility of paint acting as a bridge to allow closer examination of the conflict that emerges between a person’s desire to avoid death, nowadays manifested through digital media obsessions, and the body’s ultimate bondage to death. My research does not propose that art is a means towards transcendence, but rather the opposite; that painting invites the mind to contemplate the body as it exists and confront the disturbing, but ultimate reality …

Mechanisms In Ecology, Viorel Pâslaru

Books and Book Chapters by University of Dayton Faculty

New mechanistic philosophy has not examined explanations in ecology although they are based extensively on describing mechanisms responsible for phenomena under scrutiny. This chapter uses the example of research on the shrub Lonicera maackii (Amur honeysuckle) to scrutinize individual-level mechanisms that are generally accepted and used in ecology and confronts them with the minimal account of mechanisms. Individual-level mechanisms are for a phenomenon, are hierarchical, and absent entities play a role in their functioning. They are distinguished by the role played by properties in determining activities and organization. The chapter also considers the experimental methods for discovery of individual-level mechanisms, …

Ultraviolet-Induced Surface Grafting Of Octafluoropentyl Methacrylate On Polyether Ether Ketone For Inducing Antibiofilm Properties, Parisa Amdjadi, Hanieh Nojehdehian, Farhood Najafi, Amir Ghasemi, Massoud Seifi, Erfan Dashtimoghadam, Farahnaz Fahimipour, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Since octafluoropentyl methacrylate is an antifouling polymer, surface modification of polyether ether ketone with octafluoropentyl methacrylate is a practical approach to obtaining anti-biofilm biocompatible devices. In the current study, the surface treatment of polyether ether ketone by the use of ultraviolet irradiation, so as to graft (octafluoropentyl methacrylate) polymer chains, was initially implemented and then investigated. The Fourier-transform infrared and nuclear magnetic resonance spectra corroborated the appearance of new signals associated with the fluoroacrylate group. Thermogravimetric curves indicated enhanced asymmetry in the polymer structure due to the introduction of the said new groups. Measuring the peak area in differential scanning …

Georgia Library Association - Gla Officer Candidates For 2018, Wendy Cornelisen

Georgia Library Quarterly

No abstract provided.

Functional Selectivity Of Gpcr-Directed Drug Action Through Location Bias., Roshanak Irannejad, Veronica Pessino, Delphine Mika, Bo Huang, Philip B. Wedegaertner, Marco Conti, Mark Von Zastrow

Department of Biochemistry and Molecular Biology Faculty Papers

G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes. We show here that the homologous human β 1 -adrenergic receptor initiates an internal G s -cAMP signal from the Golgi apparatus. By developing a chemical method to acutely squelch G-protein coupling at defined membrane locations, we demonstrate that Golgi activation contributes significantly to the overall cellular cAMP response. Golgi signaling utilizes a preexisting receptor pool rather than receptors delivered from the cell surface, requiring …

Review Of Ligand Specificity Factors For Cyp1a Subfamily Enzymes From Molecular Modeling Studies Reported To-Date, Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu, Maryam Foroozesh

Faculty and Staff Publications

The cytochrome P450 (CYP) family 1A enzymes, CYP1A1 and CYP1A2, are two of the most important enzymes implicated in the metabolism of endogenous and exogenous compounds through oxidation. These enzymes are also known to metabolize environmental procarcinogens into carcinogenic species, leading to the advent of several types of cancer. The development of selective inhibitors for these P450 enzymes, mitigating procarcinogenic oxidative effects, has been the focus of many studies in recent years. CYP1A1 is mainly found in extrahepatic tissues while CYP1A2 is the major CYP enzyme in human liver. Many molecules have been found to be metabolized by both of …

Foundations For A Geobiochemical Characterization Of Mudpots In Yellowstone National Park, Georgia Dahlquist

Graduate Theses & Non-Theses

Mudpots are acidic, turbid thermal features formed by the argillic or sericitic alteration of rock with enough fluid to create a viscous feature. Prior to this research, the combination of interdisciplinary sampling for geochemistry, mineralogy, and microbiology of rhyolite hosted mudpots, particularly in chemically distinct subregions of an area, remained largely unavailable. This work discusses mudpots and nearby hot springs sampled in Yellowstone National Park (YNP) in July 2016 and the measured in situ pH, temperature, and conductivity values, and dissolved oxygen concentrations. Water, filtered via gravity pre-filtration and 1.2 μm and 0.8/0.2μm syringe filtration, yielded δD and δ18O values …

Climatic And Glacial Impact On Erosion Patterns And Sediment Provenance In The Himalayan Rain Shadow, Zanskar River, Nw India, Tara N. Jonell, Andrew Carter, Philipp Böning, Katharina Pahnke, Peter D. Clift

Faculty Publications

© 2017 Geological Society of America. Erosion is a key step in the destruction and recycling of the continental crust, yet its primary drivers continue to be debated. The relative balance between climatic and solid Earth forces in determining erosion patterns and rates, and in turn orogenic architecture, is unresolved. The monsoon-dominated frontal Himalaya is a classic example of how surface processes may drive focused denudation and potentially control structural evolution. We investigate whether there is a clear relationship between climate and erosion in the drier Himalayan rain shadow on the periphery of the Tibetan Plateau, where a coupled climate-erosion …

Acylation Of Superoxide Dismutase 1 (Sod1) At K122 Alters Sod1 Localization And Sod1-Mediated Inhibition Of Mitochondrial Respiration, Nathan William Rodriguez

Theses and Dissertations

Cu/Zn Superoxide Dismutase (SOD1), is a ubiquitous antioxidant enzyme with several emerging roles outside of its canonical function. SOD1 is also emerging in central roles in cancer and neurodegenerative pathologies. Little is known about SOD1 regulation, particularly at a post-translational level. Post-translational modifications (PTMs) play an important role in enabling proteins to rapidly respond to their environment. Therefore, identifying specific PTMs involved in protein regulation represents a powerful opportunity to interfere with any associated pathologies. This work employs proteomics to identify mechanisms of post-translation regulation on cell survival signaling proteins. We focused on SOD1, which protects cells from oxidative stress. …

Differences In German Youth Gender Ideologies: The Relationship Between Family Structure And Doing Gender, Alyssa Jane Alexander

Theses and Dissertations

Gender ideologies, which are constantly changing, are important for many outcomes in life, but the majority of gender ideology research focuses mainly on adults. Past research studying adult gender ideologies finds that adults' current relationship status affects their ideologies. For instance, divorced adults hold egalitarian ideologies more than stable married adults do (Davis, Greenstein and Marks 2007). Researchers attribute this finding to the types of gender behaviors adults perform with their partner or alone. What about youth? Understanding how these ideologies develop earlier in life is important, yet research rarely focuses on youth gender ideologies or their development. My research …

Co-Localization Patterns Of Aquaporin-4 With Amyloid Beta And Cd68 In Alzheimer's Disease And Cerebrovascular Disease, Anthony Bryan Crum

Theses and Dissertations

Aquaporin-4 (AQP4) is a key component in maintaining proper glymphatic flow. In recent years, the glymphatic system has been discovered and approached as a major factor in amyloid plaque clearance in Alzheimer's disease. This study examines the depolarization of AQP4 from the astrocytic endfeet and subsequent co-localization with amyloid plaques in the hippocampus and subiculum. Results show a significant pattern of co-localization in advanced Alzheimer's disease, as well as increases in AQP4 in cerebrovascular disease. This pattern shows AQP4 should be approached as a promising therapeutic area in future research.

Perceived Effects Of Open Textbook Usage On Secondary Science Classroom Practice, Stacie Lee Mason

Theses and Dissertations

Open Educational Resources (OER) provide openly licensed alternatives to commercial instructional materials. Proponents of K-12 OER suggest that their benefits include cost savings, increased access, improved quality, and increased teacher professionalism or empowerment. While the small body of K-12 OER research is growing, perceived benefits of K-12 OER usage have not yet been proven. The purpose of this qualitative study is to understand whether certain potential benefits were being realized by a group of secondary teachers using open science textbooks. In surveys and interviews, teachers were asked to describe their classroom practice before and after adopting an open textbook, including …

Do Adults Diagnosed With Autism Spectrum Disorders Have An Advantage In Real-World Visual Search Tasks?, Nicholas Charles Russell

Theses and Dissertations

Individuals with Autistic Spectrum Disorders (ASD) often perform better than typically developing (TD) individuals in simple, albeit difficult, visual search tasks. This ability is often attributed to a lack of drive for coherence or superior local processing. We compare thirty adults with ASD with forty-nine TD individuals and twenty-seven adults with anxiety (ANX) across two real-world visual search tasks. Individuals had to find either a number superimposed over a real-world scene ("œno context" condition) or an object located in a contextually relevant location ("œcontext" condition). Each participant completed forty-one trials in each condition, each with a unique scene. Eye movements …

Adapting Dracula: The Afterlives Of Stoker's Memes In Nosferatu (1922) And Dracula (1979), Ian Duncan Mcarthur

Theses and Dissertations

Dracula is a narrative that has risen above its own origins, having been translated and adapted across mediums it has inundated culture with vampires. However, with each adaptation the narrative and characters adapt into something new. This study is interested in the mechanism behind this evolution and argues that memes and, and their interpretations, are largely responsible for these shifts across adaptations. Three memes, in particular, tend to be adapted in films of Dracula. They include Dracula's appearance, Mina's empowerment, and the nature of the bite that they share. This analysis covers how these memes functioned in Stoker's original …

Correlates Of Risky Sexual Behavior In The People's Republic Of China, Kersti A. Spjut

Theses and Dissertations

Risky sexual behaviors, or behaviors with the risk of an adverse health outcome, are on the rise. Rates of Sexually Transmitted Infections (STIs) are also on the rise. Research suggests that several variables are closely related to human sexual behavior, namely sexual attitudes, sexual knowledge, and gender. Individuals with more permissive sexual attitudes tend to engage in riskier sexual behaviors. Studies examining the relationship between sexual knowledge and risky sexual behavior show both positive and negative associations. Although risky behaviors can occur between partners of any gender, the present study focuses on heterosexual relationships.The present study uses data from a …

Comparing The Awl And Avl In Textbooks From An Intensive English Program, Michelle Morgan Hernandez

Theses and Dissertations

Academic vocabulary is an important determiner of academic success for both native and non-native speakers of English (Corson, 1997; Gardner, 2013; Hsueh-chao & Nation, 2000). In an attempt to address this need, Coxhead (2000) developed the Academic Word List (AWL)—a list of words common across a range of academic disciplines; however, Gardner & Davies (2014) identified potential limitations in the AWL and have more recently produced their own list of core academic vocabulary—the Academic Vocabulary List (AVL). This study compares the occurrences of the AWL and AVL word families in an intensive English program (IEP) corpus of 50 texts to …

Sentence-Level Construction Methods: Skills Taught Are Skills Used, Susan Allsop Shelton

Theses and Dissertations

The findings of this study predict that students who utilize five specific sentence constructions on timed single-draft writing compositions will have higher holistic scores than students who do not utilize the specific constructions. Students in the treatment group who were taught to use the five constructions through thorough and consistent instruction in a semester length first year writing course showed statistically significant gains, 4.698 points on a 0-18 scale, based on comparison of pre-test and post-test writing samples. The findings suggest that specific style instruction at the sentence level should be part of the first year writing course curriculum, and …

Role Of Terrestrial Organic Matter In Food Webs Of The Rocky Intertidal Zone, Douglas O. Fairbanks

Theses and Dissertations

Terrestrial organic matter (TOM) constitutes an important source of energy in many aquatic environments (streams, lakes, wetlands). This is the first study to examine the role of TOM in food webs of the rocky intertidal zone. We compared the consumption of red alder leaves (Alnus rubra) to common marine sources of drifting detritus along the southern Oregon coast (Nereocystis luetkeana, Phyllospadix spp., and Fucus gardneri). We used short term (hours to days) and long term (months) feeding experiments to compare the rate of consumption among each plant species during the Spring and Fall of 2014 …

Ixazomib Enhances Parathyroid Hormone-Induced Β-Catenin/T-Cell Factor Signaling By Dissociating Β-Catenin From The Parathyroid Hormone Receptor., Yanmei Yang, Hong Lei, Ya-Wei Qiang, Bin Wang

Center for Translational Medicine Faculty Papers

The anabolic action of PTH in bone is mostly mediated by cAMP/PKA and Wnt-independent activation of β-catenin/T-cell factor (TCF) signaling. β-Catenin switches the PTH receptor (PTHR) signaling from cAMP/PKA to PLC/PKC activation by binding to the PTHR. Ixazomib (Izb) was recently approved as the first orally administered proteasome inhibitor for the treatment of multiple myeloma; it acts in part by inhibition of pathological bone destruction. Proteasome inhibitors were reported to stabilize β-catenin by the ubiquitin-proteasome pathway. However, how Izb affects PTHR activation to regulate β-catenin/TCF signaling is poorly understood. In the present study, using CRISPR/Cas9 genome-editing technology, we show that …

Revealing The Cytotoxic Potential Of Medicinal Folklore: Bombax Ceiba L., Hafiz Tahsin Ullah Jan, Syeda Masooma Ali, Amna Shabbir, Bakht Nasir, Syeda Saniya Zahra

Journal of Bioresource Management

Current study was intended to investigate the cytotoxic potential of Bombax ceiba L.by executing a wide range of in vitro assays. Brine shrimp lethality assay showed that stem wood’s chloroform (CH) extract was highly toxic (LC₅₀ 42.41 ± 3.40 µg/ml) followed by acetone : ethyl acetate (AC:EA) extract with LC₅₀ value of 72.92 ± 4.41 µg/ml. n-Hexane (NH) extract of root wood part caused 70.95 ± 1.77% inhibition of THP-1 cell line at 20 μg/ml concentration (IC₅₀ 15 ± 0.56 µg/ml). NH and CH extracts of stem wood part showed promising results in protein kinase inhibitory assay …

Temperature As A Circadian Marker In Older Human Subjects: Relationship To Metabolic Syndrome And Diabetes, Brianna D. Harfmann, Elizabeth A. Schroder, Jonathan H. England, Natalie J. Senn, Philip M. Westgate, Karyn A. Esser, Philip A. Kern

Internal Medicine Faculty Publications

Background: Circadian rhythms are characterized by approximate 24-hour oscillations in physiological and behavioral processes. Disruptions in these endogenous rhythms, most commonly associated with shift work and/or lifestyle, are recognized to be detrimental to health. Several studies have demonstrated a high correlation between disrupted circadian rhythms and metabolic disease. The aim of this study was to determine which metabolic parameters correlate with physiological measures of circadian temperature amplitude (TempAmp) and stability (TempStab).

Methods: Wrist skin temperature was measured in 34 subjects (ages 50 to 70, including lean, obese, and diabetic subjects) every 10 minutes for 7 consecutive days. Anthropometric measures and …

The Write Stuff - Summer 2017 (Vol. 14, No. 3), Research Medical Library

Write Stuff 2017

• Grant Writers' seminars return in October
• Increase INTEREST in your grant proposals
• Academic search engine optimization: Help readers find your research
• Plagiarism policies of journals preferred by MD Anderson authors
• Tips for writing Introduction sections for NIH “resubmission” grant applications
• Unusual terms used in scientific writing and publishing: Journalology

Implementation Science And Fidelity Measurement: A Test Of The 3-5-7 Model™, Ramona Denby-Brinson, Judy Tudor, Darla Henry, Stephanie Hodge Wolfe, Efren Gomez, Keith A. Alford

Lincy Institute Reports and Briefs

Children and youths engaged with the child welfare system can experience grief and loss as a result of trauma, broken relationships, and inadequate attachments. Interventionists are often challenged to implement effective strategies that help youths to reestablish trusting relationships and to promote overall psychological well-being. A 5-year federal demonstration project funded by the U.S. Department of Health and Human Services, Children’s Bureau, guided by an implementation science model, sought to increase well-being in youths age 12–21 who were involved in the child welfare system. The 3-5-7 Model™, a strengths-based approach that empowers children, youths, and families to engage in grieving …

Fresh From The Farm: Regulating Concentrated Animal Feeding Operations For Antibiotic Abuse In Tennessee, Elizabeth B. Stagich

University of Memphis Law Review

No abstract provided.

Crystal Structure Of Yersinia Pestis Virulence Factor Yfea Reveals Two Polyspecific Metal-Binding Sites, Christopher D. Radka, Lawrence J. Delucas, Landon S. Wilson, Matthew B. Lawrenz, Robert D. Perry, Stephen G. Aller

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Gram-negative bacteria use siderophores, outer membrane receptors, inner membrane transporters and substrate-binding proteins (SBPs) to transport transition metals through the periplasm. The SBPs share a similar protein fold that has undergone significant structural evolution to communicate with a variety of differentially regulated transporters in the cell. In Yersinia pestis, the causative agent of plague, YfeA (YPO2439, y1897), an SBP, is important for full virulence during mammalian infection. To better understand the role of YfeA in infection, crystal structures were determined under several environmental conditions with respect to transition-metal levels. Energy-dispersive X-ray spectroscopy and anomalous X-ray scattering data show that …

Evaluation Of The Tennessee Move On When Ready Program, Tennessee. Comptroller Of The Treasury.

Office of Research and Education Accountability

No abstract provided.

2017 Report On The Status Of Emergency Medical Services For Children, Tennessee. Department Of Health.

EMS and BLHCF Annual Report on Pediatric Emergency Care

No abstract provided.

An Outdoor Curriculum Based In Phenology And Ecology Promoting The Environmental Stewardship Of Middle School Students, Alyssa R. Polovitz

School of Education and Leadership Student Capstone Projects

Many students are not spending enough time in nature, and therefore may lack a passion and understanding of the environment. The literature defines this problem as the nature-deficit disorder, and it explains a need for outdoor and place-based education. This capstone developed a curriculum to help answer the research question, How can an outdoor curriculum based in phenology and ecology that promotes environmental stewardship in middle school students be developed? This emerged from the educator’s passion for the outdoors and nature and helping students develop a similar love and appreciation for the environment. Results provide a weeklong outdoor study that …

Developing A Teacher Guidebook To Increase Outdoor Education In Schools, Patrick Schuette

School of Education and Leadership Student Capstone Projects

An outdoor education guidebook was developed to help teachers start outdoor education courses, increase student engagement, and develop intrapersonal and interpersonal skills in students. Outdoor education is about much more than learning content information in a classroom; it is the class and teaching mindset which rekindles students’ passion for learning and discovery. Outdoor education best practice consists of place-based learning where students learn physical and mental skills with the outcome of success being directly related to those skills. Outdoor education will look different depending on location because it is influenced by local environmental, students, resources, and culture. The outdoor education …