Digital Commons Network^™

A Simple And Accurate Rule-Based Modeling Framework For Simulation Of Autocrine/Paracrine Stimulation Of Glioblastoma Cell Motility And Proliferation By L1cam In 2-D Culture., Justin Caccavale, David Fiumara, Michael Stapf, Liedeke Sweitzer, Hannah J. Anderson, Jonathan Gorky, Prasad Dhurjati, Deni S. Galileo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Glioblastoma multiforme (GBM) is a devastating brain cancer for which there is no known cure. Its malignancy is due to rapid cell division along with high motility and invasiveness of cells into the brain tissue. Simple 2-dimensional laboratory assays (e.g., a scratch assay) commonly are used to measure the effects of various experimental perturbations, such as treatment with chemical inhibitors. Several mathematical models have been developed to aid the understanding of the motile behavior and proliferation of GBM cells. However, many are mathematically complicated, look at multiple interdependent phenomena, and/or use modeling software not freely available to the research …

On Location, K Parker

School of Art, Design and Architecture

Kayla Parker’s film On Location poses questions of radicalism both in terms of audio visual aesthetics and of filmmaking methodology in addition to more overtly political issues of environmental degradation, human and non-human relations and marginalised femininities. Acknowledging that her method of filmmaking is ‘predicated on there being no conscious aim either before or during the making process’, Parker reverse engineers an experimental approach to landscape filmmaking that synthesises phenomenology, écriture feminine, structural materialism and critical geography. The result is a beautiful depiction of the countryside hollow way visited by the British avant-garde filmmaker and performance artist, Annabel Nicolson, forty …

Safety First: Fostering The Neurological Experience Of Safety In Dance/Movement Therapy Sessions For Survivors Of Sexual Trauma, Chelsea Joy Davis

Creative Arts Therapies Theses

The purpose of this clinical case study was to explore and describe how a neurological experience of safety was fostered for survivors of sexual trauma in dance/movement therapy sessions at a community-based rape-crisis counseling center. This study focused on how the theories of trauma-informed therapy and dance/movement therapy were applied to clinical practice with survivors of sexual trauma in order to shift them out of trauma-related responses. Reflections on this process were captured via structured and narrative journaling, which was then synthesized by highlighting and interpreting common themes that emerged. Findings indicated that externalizing trauma-related responses using symbolic imagery and …

A Study On Organic Tomatoes: Effect Of A Biostimulator On Phytochemical And Antioxidant Activities, Varinder Sidhu, Dilip Nandwani, Li Wang, Ying Wu

Agricultural and Environmental Sciences Faculty Research

The objective of the present study is to investigate nutritional and antioxidant activity of four types of organic tomato cultivars. The differences in tomato quality are also tested between groups with or without treatment using an organic biostimulator, Stimplex. Total phenolic compounds (TPC), lycopene, 𝛽-carotene, DPPH free radical scavenging activity, reducing power, and color parameters were investigated in the current study. The results showed that there was no significant difference in TPC among cultivars regardless of Stimplex treatment. Higher lycopene and 𝛽-carotene were obtained in Stimplex treated tomatoes. Lycopene and -carotene contents were significantly different among cultivars (𝑃<0.05). DPPH scavenging activity in controlled group was significantly higher than that in the Stimplex treated tomatoes (𝑃<0.05). No significant difference in reducing power was detected among cultivars treatment groups. The study showed that the darker the tomato color, the higher the lycopene and 𝛽-carotene contents and the stronger the reducing power.

Self-Esteem In Spanish-Speaking Latinos In Northwest Ohio, Mckenna Freeman

Honors Projects

Self-esteem is a widely-studied construct across many disciplines of social science. However, previous research regarding self-esteem and language barriers has focused primarily on children and adolescent populations, while much less research has examined this relationship among adults. The current study measures linguistic acculturation and self-esteem in both Latino and control adult samples. Hypothesis 1 states that participants in the Latino sample would report significantly lower self-esteem than the control sample. Hypothesis 2 states that linguistic acculturation levels in Spanish speaking Latinos would be positively correlated with self-esteem. Finally, a research question was addressed measuring the differences in self-esteem between foreign …

Expression And Role Of Gonadotropin-Releasing Hormone 2 And Its Receptor In Mammals, Amy Desaulniers, Rebecca A. Cederberg, Clay A. Lents, Brett R. White

Department of Animal Science: Faculty Publications

Gonadotropin-releasing hormone 1 (GnRH1) and its receptor (GnRHR1) drive mammalian reproduction via regulation of the gonadotropins. Yet, a second form of GnRH (GnRH2) and its receptor (GnRHR2) also exist in mammals. GnRH2 has been completely conserved throughout 500 million years of evolution, signifying high selection pressure and a critical biological role. However, the GnRH2 gene is absent (e.g., rat) or inactivated (e.g., cow and sheep) in some species but retained in others (e.g., human, horse, and pig). Likewise, many species (e.g., human, chimpanzee, cow, and sheep) retain the GnRHR2 gene but lack the appropriate coding sequence to produce a full-length …

The Effects Of Equine Assisted Learning On Emotional Intelligence Competencies And Leadership Skills, Jade E. Rauen

Honors Theses

The Effects of Equine Assisted Learning on

Emotional Intelligence Competencies and Leadership Skills

Jade Rauen

Dr. Kelly L. Leigers, PhD, OTR/L, Department of Occupational Science and Occupational Therapy

Since the development and understanding of the term emotional intelligence (EI), researchers and businessmen alike have strived to find a way to improve EI competencies. Equine-Assisted Learning (EAL) is a branch of Equine Therapy that uses the horse to facilitate change in humans. In recent years, EAL has been applied to the field of leadership development. Can a horse intrinsically instill competencies that effect leadership skills in humans? There is limited literature …

Fall 2017 Commencement Program, University Of Alabama In Huntsville

Commencement Programs

No abstract provided.

Nanostructured Apatite-Mullite Glass-Ceramics For Enhanced Primary Human Osteoblast Cell Response, Gordon Cooke, Conor Dunne, Sarah Keane, Daithi De Faoite, Seamas Donnelly, Kenneth Stanton

Articles

This work investigates the difference in viability of primary human foetal osteoblast cells on a glass-ceramic surface with nanoscale topography relative to viability on a smooth glass-ceramic surface containing a bioactive phase. Apatite-mullite glass-ceramics containing bioactive fluorapatite (Ca₁₀(PO₄)₆F₂) and bioinert mullite (Si₂Al₆O₁₃) were synthesised and subsequent heat-treatment was optimised to form nano-sized fluorapatite crystals. Etching was used to selectively remove the bioactive phase, producing a surface with disordered nanoscale topography. Cells were seeded onto a smooth polished glass-ceramic substrate with the bioactive phase intact, an etched …

December Agenda, Wku Graduate Council

Graduate School

Meeting agenda.

Landscape Of Change: An Ecocritical View Of Willa Cather’S My Antonia, Melissa Taitano

Agora

No abstract provided.

Accepted Science And Rejected Sexuality: The Revealing Nature Of The Uncanny In Aldous Huxley’S Brave New World, Caitlin Pettman

Agora

No abstract provided.

Ua45/6 Commencement Program, Wku Registrar

WKU Administration Documents

Commencement program listing graduates.

Commencement Convocation Program, Usf, Graduate, December 9, 2017, University Of South Florida

USF Graduation and Convocation Programs

Honorary Doctor of Engineering and Nursing - Patricia Flatley-Brennan

10 A&S Students Named Margaret Boyd Scholars, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Finding Meaning In The Lack Thereof: An Analysis Of Nietzsche's And Sartre's Responses To The Problem Of Existential Nihilism, Daniel J. Hassall

Honors Theses

There have been countless philosophers who have attempted to create ways that humanity can overcome the threat of existential nihilism and the loss of objective meaning. Two of the most influential philosophers who have attempted to do this are Friedrich Nietzsche and Jean-Paul Sartre. This paper analyzes both of their philosophical solutions to the problem of nihilism, comparing and contrasting. While similar in many respects, Nietzsche and Sartre differ on several key aspects: they approach nihilism slightly differently, they have different views about ethics and subjectivity, and Nietzsche is a determinist while Sartre advocates a radical free will. When comparing …

Hunger Games: Policies To Address Food Deserts In Rhode Island's Low Income Communities, Jessi Mcneill

Pell Scholars and Senior Theses

This policy paper examines the global, health, and social implications of food deserts in the state of Rhode Island. This paper assesses the inception of the food desert phenomenon and draws attention to three policy options for the state. While there is sufficient research on food deserts in large cities like New York and Philadelphia, little information is available regarding the implications of food deserts and policy options available to provide low-income Rhode Islanders with healthy, affordable food. Research methodology consists of site visits and interviews, as well as research courtesy of the 2017 Rhode Island Food Strategy and nonprofit …

Trajectories Of Change In Mediterranean Holocene Vegetation Through Classification Of Pollen Data, Ralph M. Fyfe, Jessie Woodbridge, C. Neil Roberts

School of Geography, Earth and Environmental Sciences

© 2017 Springer-Verlag GmbH Germany, part of Springer Nature Quantification of vegetation cover from pollen analysis has been a goal of palynologists since the advent of the method in 1916 by the great Lennart von Post. Pollen-based research projects are becoming increasingly ambitious in scale, and the emergence of spatially extensive open-access datasets, advanced methods and computer power has facilitated sub-continental analysis of Holocene pollen data. This paper presents results of one such study, focussing on the Mediterranean basin. Pollen data from 105 fossil sequences have been extracted from the European Pollen database, harmonised by both taxonomy and chronologies, and …

Perbandingan Pengukuran Luas Daun Kedelai Dengan Metode Gravimetri, Regresi Dan Scanner, Aep Wawan Irwan, Fiky Yulianto Wicaksono

Jurnal Kultivasi

Luas daun merupakan salah satu parameter penting yang diperlukan untuk mengetahui pertumbuhan tanaman kedelai (Glycine max L.), oleh karena itu diperlukan teknik pengukuran yang cepat dan tepat. Dengan mengetahui luas daun, maka akan diketahui indeks luas daunnya dengan cara membaginya dengan luas kanopi tanaman. Selain pengukuran dengan menggunakan Leaf Area Meter, pengukuran dengan menggunakan metode dasar (gravimetri) masih sering dipergunakan. Penggunaan metode lainnya adalah dengan cara regresi dan penggunaan alat scanner, dimana metode tersebut mempunyai kelebihan dan kekurangannya masing-masing. Untuk pelaksanaan pengukuran luas daun kedelai ini digunakan tanaman kedelai kultivar Anjasmoro yang ditanam di polybag di Kebun Percobaan Hidroponik Fakultas …

Multiplikasi Tunas Mikro Pisang (Musa Paradisiaca L.) ‘Raja Bulu’ Secara In Vitro Pada Berbagai Jenis Dan Konsentrasi Sitokinin, Tiara Elma, Erni Suminar, Syariful Mubarok, Anne Nuraini

Jurnal Kultivasi

Terbatasnya ketersediaan bibit pisang bermutu di Indonesia disebabkan oleh masih rendahnya jumlah dan kualitas bibit pisang yang dihasilkan melalui metode konvensional. Waktu yang dibutuhkan untuk mendapatkan bibit cukup lama, oleh karena itu digunakan suatu metode perbanyakan untuk menghasilkan bibit dalam waktu yang relatif singkat melalui metode kultur jaringan. Tujuan dari penelitian ini adalah untuk mendapatkan salah satu jenis dan konsentrasi sitokinin terbaik dalam meningkatkan laju multiplikasi tunas pisang raja bulu secara in vitro. Percobaan dilaksanakan dari bulan November 2016 sampai bulan Maret 2017 di Laboratorium Kultur Jaringan dan Teknologi Benih Fakultas Pertanian Universitas Padjadjaran di Jatinangor, Sumedang. Rancangan Acak Lengkap …

Introducing Volume 3, Editorial Board

Spora: A Journal of Biomathematics

This report provides a brief introduction to Spora and what you can expect from the articles included in this volume.

Impacts Of Prenatal And First-Year Brain Development, Jennifer Brown

The Compass

No abstract provided.

The Compass, Issue 4, Arcadia University, Honors Program

The Compass

No abstract provided.

Knowledge Retention Across Curricular Models: An International Collaboration, Rosalyn Jurjus, Abdo Jurjus, Gisela Butera

Anatomy and Regenerative Biology Faculty Posters and Presentations

Program symposium.

[2017-12-08] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors

VCU Board of Visitors Minutes

Official minutes of the VCU Board of Visitors and its Executive Committee.

Panther - December 2017, Prairie View A&M University

PV Panther Newspapers 2017

No abstract provided.

2017-12-08, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

Using Mixed Effects Modeling To Quantify Difference Between Patient Groups With Diabetic Foot Ulcers, Rachel French

Mahurin Honors College Capstone Experience/Thesis Projects

When diabetes progresses, many patients suffer from chronic foot ulcers. In a study described in Matrix Metalloproteinases and Diabetic Foot Ulcers (Muller et al., 2008), sixteen patients with diabetic foot ulcers were examined throughout a twelve week healing period. During this period, levels of matrix metalloproteinases (MMP-1), their inhibitors (TIMP-1), and the extracellular matrix in a wound area were measured at distinct time intervals for each patient. The ratios of these healing components are vital in determining whether a wound will heal or become chronic and never properly heal. Connecting Local and Global Sensitivities in a Mathematical Model for Wound …

Commencement Convocation Program, Usf, Baccalaureates, December 8, 2017, University Of South Florida

USF Graduation and Convocation Programs

Outstnding Graduate - Alexis Drees; Honorary Doctor of Science - Andrew Hamilton; King O'Neal Scholars - Aneesa Ali, Andrew Apugliese, David Blanchard, Janet Diaz Montes, Mary Edwards, Shayna Gurvitz, Bonnie Hogan Lowlery, Ryan Kurtz, Robert Lockridge, Natalie Meyer, Rachel Moore, Ashley Nandrasy, Carlos Pena Duran, Brittany Raymond, Paul Rogers, Nicholas Romano, Khadijah Tiamiyu, Xamil Vega, Amy Whitehurst, George Wolf, and Alexander Zhideev

Safety And Efficacy Of Apremilast Through 104 Weeks In Patients With Moderate To Severe Psoriasis Who Continued On Apremilast Or Switched From Etanercept Treatment: Findings From The Liberate Study., K Reich, M Gooderham, A Bewley, L Green, J Soung, R Petric, J Marcsisin, J Cirulli, R Chen, V Piguet

Dermatology Faculty Publications

Background

Apremilast, an oral phosphodiesterase‐4 inhibitor, has demonstrated efficacy in patients with moderate to severe psoriasis.

Objective

To evaluate long‐term efficacy and safety of apremilast in biologic‐naive patients with moderate to severe plaque psoriasis and safety of switching from etanercept to apremilast in the phase 3b LIBERATE trial.

Methods

Two hundred fifty patients were randomized to placebo, apremilast 30 mg BID or etanercept 50 mg QW through Week 16; thereafter, all patients continued or switched to apremilast through Week 104 (extension phase). Skin, scalp and nail involvement at Weeks 16, 52 and 104 were assessed using the Psoriasis Area and …