Digital Commons Network^™

Rhythm As Logos In Native World-Ordering, Sierra Druley

Episteme

No abstract provided.

Charles Taylor’S Langue/Parole And Alasdair Macintyre’S “Networks Of Giving And Receiving” As A Foundation For A Positive Anti-Atomist Political Theory, Robert Moore

Episteme

No abstract provided.

Cognition And Sensation: A Reconstruction Of Herder’S Quasi-Empiricism, Philip Yaure

Episteme

No abstract provided.

Against Fodor, Rafael Ventura

Episteme

No abstract provided.

Spurious Soul: A Modern Critique Of The Thomistic Soul, Eric Chase

Episteme

No abstract provided.

Rwu Marine Scientists To Collaborate On $3 Million Nsf Grant Investigating Aquatic Viruses, Public Affairs, Roger Williams University, University Of Delaware

Featured News Story

Professors Marcia Marston and Koty Sharp join research team from four universities to study how marine and aquatic viruses impact microbes.

Influence Of Adrenergic Agonists On Early Atherosclerotic Events, Jesica S. Westwright

Open Access Theses

Psychosocial stress is related to cardiovascular disease (CVD) morbidity and mortality, but the mechanisms of this relationship remain incompletely understood. The present in vitro study investigated the effect of catecholamines, a subclass of stress hormones, on the early CVD processes of monocyte adhesion and migration. For adhesion, THP-1 monocytes (MO) and human aortic endothelial cells (HAEC) were separately treated with catecholamines prior to static adhesion assay. MO migration was investigated using a Transwell migration protocol. HAEC adrenergic receptor mRNA expression and HAEC adhesion molecule surface expression were evaluated. Adrenergic agonism/antagonism experiments were utilized to determine the role of specific adrenergic …

Unraveling The Interactions Of The Physiological Reductant Flavodoxin With The Different Conformations Of The Fe Protein In The Nitrogenase Cycle, Natasha Pence, Monika Tokmina-Lukaszewska, Zhi-Yong Yang, Rhesa N. Ledbetter, Lance C. Seefeldt, Brian Bothner, John W. Peters

Chemistry and Biochemistry Faculty Publications

Nitrogenase reduces dinitrogen (N2) to ammonia in biological nitrogen fixation. The nitrogenase Fe protein cycle involves a transient association between the reduced, MgATP-bound Fe protein and the MoFe protein and includes electron transfer, ATP hydrolysis, release of Pi, and dissociation of the oxidized, MgADP-bound Fe protein from the MoFe protein. The cycle is completed by reduction of oxidized Fe protein and nucleotide exchange. Recently, a kinetic study of the nitrogenase Fe protein cycle involving the physiological reductant flavodoxin reported a major revision of the rate-limiting step from MoFe protein and Fe protein dissociation to release of Pi. Because the Fe …

A Bipyridine-Ligated Zinc(Ii) Complex With Bridging Flavonolate Ligation: Synthesis, Characterization, And Visible-Light-Induced Co Release Reactivity, Shayne Sorenson, Marina Popova, Atta M. Arif, Lisa M. Berreau

Chemistry and Biochemistry Faculty Publications

Metal-flavonolate compounds are of significant current interest as synthetic models for quercetinase enzymes and as bioactive compounds of importance to human health. Zinc-3-hydroxyflavonolate compounds, including those of quercetin, kampferol, and morin, generally exhibit bidentate coordination to a single ZnII center. The bipyridine-ligated zinc-flavonolate compound reported herein, namely bis(μ-4-oxo-2-phenyl-4H-chromen-3-olato)-κ3O3:O3,O4;κ3O3,O4:O3-bis[(2,2′-bipyridine-κ2N,N′)zinc(II)] bis(perchlorate), {[Zn2(C15H9O3)2(C10H8N2)2](ClO4)2}n, (1), provides an unusual example of bridging 3-hydroxyflavonolate ligation in a dinuclear metal complex. The symmetry-related ZnII centers of (1) exhibit a distorted octahedral geometry, with weak coordination of a perchlorate anion trans to the bridging deprotonated O atom of the flavonolate ligand. Variable-concentration conductivity measurements provide evidence that, when …

Impact Of Stress, Fear And Anxiety On The Nociceptive Responses Of Larval Zebrafish, Javier Lopez-Luna, Qussay Al-Jubouri, Lynne U. Sneddon

Sentience Collection

Both adult and larval zebrafish have been demonstrated to show behavioural responses to noxious stimulation but also to potentially stress- and fear or anxiety- eliciting situations. The pain or nociceptive response can be altered and modulated by these situations in adult fish through a mechanism called stress-induced analgesia. However, this phenomenon has not been described in larval fish yet. Therefore, this study explores the behavioural changes in larval zebrafish after noxious stimulation and exposure to challenges that can trigger a stress, fear or anxiety reaction. Five-day post fertilization zebrafish were exposed to either a stressor (air emersion), a predatory fear …

Ice Bear: The Cultural History Of An Arctic Icon By Michael Engelhard, Geneviève Pigeon

The Goose

Review of Michael Engelhard's Ice Bear: The Cultural History of an Arctic Icon.

Science Café | Kicks Off With Lisa Crockett On, Sept. 20, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Plant Biology Norman S Cohn Research Symposium, Sept. 9, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

White-Nose Syndrome Pathology Grading In Nearctic And Palearctic Bats, Jiri Pikula, Sybill K. Amelon, Hana Bandouchova, Tomáš Bartonička, Hana Berkova, Jiri Brichta, Sarah Hooper, Tomasz Kokurewicz, Miroslav Kolarik, Bernd Köllner, Veronika Kovacova, Petr Linhart, Vladimir Piacek, Gregory G. Turner, Jan Zukal, Natália Martínková

KIP Articles

No abstract provided.

Bedwell Named Chair Of Biochemistry And Molecular Genetics, Katelyn Howard

Browse All News

No abstract provided.

Sepsis, Sarah Jones

Nursing Student Class Projects (Formerly MSN)

Sepsis is a dysregulation of the inflammatory response, termed systemic inflammatory response syndrome or SIRS, caused by stimulation of an infectious process. Sepsis often leads to organ dysfunction and increased morbidity, mortality and financial burdens. The goal of treatment is to initiate appropriate antimicrobial therapies, target the underlying infection, optimize intravascular volume, provide fluid resuscitation and maintain adequate perfusion and stroke volume (Taeb, Hooper & Marik, 2017).

Timing of treatment and early detection of sepsis is critical to patients with early warning signs. Sharing this information and potentially making a difference in the outcomes of patients presenting with early signs …

Ecological Niche Modeling Of The Genus Papio, Amanda J. Fuchs

Theses and Dissertations

Ecological niche modeling investigates how climatic variables have influenced taxonomic diversity in Papio. Models performed well suggesting climatic variables influence the distribution of baboon species. Niche overlap among all possible pairs of taxa determined that species exhibited significantly different niches. The results of these models support a parapatric speciation scenario.

Microbiome Analysis Of Two Sympatric Fungus-Gardening Ants, Trachymyrmex Septentrionalis And Trachymyrmex Turrifex, Mattea Allert

Biology Theses

The fungus gardening-ant system is considered a complex, multi-tiered symbiosis between the ants, their fungus, and their corresponding microbes. We examine the bacterial microbiome of Trachymyrmex septentrionalis and Trachymyrmex turrifex ants and their corresponding fungus, using 16S rRNA, over a large geographical region to determine if horizontal transmission was occurring. The goals of this study was to determine how the ant microbiome was transmitted and how the fungus microbiome was transmitted. We determined that the microbiomes of T. septentrionalis and T. turrifex ants were different because of the species, while the microbiomes of T. septentrionalis and T. turrifex fungi were …

Volume 54, Number 51: August 02, 2017, University Of North Dakota

University Letter Archive

No abstract provided.

Responses Of Agroecosystems To Climate Change: Specifics Of Resilience In The Mid-Latitude Region, Menas Kafatos, Seung Hee Kim, Chul-Hee Lim, Jinwon Kim, Woo-Kyun Lee

Mathematics, Physics, and Computer Science Faculty Articles and Research

This study examines the productivity and resilience of agroecosystems in the Korean Peninsula. Having learned valuable lessons from a Chapman University project funded by the United States Department of Agriculture which concentrated on the semi-arid region of southwestern United States, our joint Korea—Chapman University team has applied similar methodologies to the Korean Peninsula, which is itself an interesting study case in the mid-latitude region. In particular, the Korean Peninsula has unique agricultural environments due to differences in political and socioeconomic systems between South Korea and North Korea. Specifically, North Korea has been suffering from food shortages due to natural disasters, …

Efficient Template-Based Nanomanufacturing Of Carbon Nanotube Arrays For Cell Applications, Adeel Ahmed

Theses

Carbon nanotube arrays have been found to be highly effective at carrying out intracellular delivery of cargo at high efficiencies while ensuring cell viability. Template based chemical vapor deposition is a commonly used process to fabricate these arrays. However, current etching methods used to expose carbon nanotubes from templates are expensive and time consuming. The high cost and time-consuming processes currently required to fabricate such arrays are factors which limit the commercialization of this technology and inhibit scope for larger research programs. In this thesis, alternative nanofabrication methods were explored with the aim of making the fabrication of CNT arrays …

Cytonuclear Discordance In The Florida Everglades Invasive Burmese Python (Python Bivittatus) Population Reveals Possible Hybridization With The Indian Python (P. Molurus), Margaret E. Hunter, Nathan A. Johnson, Brian J. Smith, Michelle C. Davis, John S.S. Butterfield, Ray W. Snow, Kristen M. Hart

United States Geological Survey: Staff Publications

The invasive Burmese python (Python bivittatus) has been reproducing in the Florida Everglades since the 1980s. These giant constrictor snakes have caused a precipitous decline in small mammal populations in southern Florida following escapes or releases from the commercial pet trade. To better understand the invasion pathway and genetic composition of the population, two mitochondrial (mtDNA) loci across 1,398 base pairs were sequenced on 426 snakes and 22 microsatellites were assessed on 389 snakes. Concatenated mtDNA sequences produced six haplotypes with an average nucleotide and haplotype diversity of π = 0.002 and h = 0.097, respectively. Samples collected …

State V. Searcy Respondent's Brief Dckt. 44487

Not Reported

No abstract provided.

Future Orientation, Social Support, And Psychological Adjustment Among Left-Behind Children In Rural China: A Longitudinal Study, Shaobing Su, Xiaoming Li, Danhua Lin, Maoling Zhu

Faculty Publications

Existing research has found that parental migration may negatively impact the psychological adjustment of left-behind children. However, limited longitudinal research has examined if and how future orientation (individual protective factor) and social support (contextual protective factor) are associated with the indicators of psychological adjustment (i.e., life satisfaction, school satisfaction, happiness, and loneliness) of left-behind children. In the current longitudinal study, we examined the differences in psychological adjustment between left-behind children and non-left behind children (comparison children) in rural areas, and explored the protective roles of future orientation and social support on the immediate (cross-sectional effects) and subsequent (lagged effects) status …

Bow-Tie Signaling In C-Di-Gmp: Machine Learning In A Simple Biochemical Network, Jinyuan Yan, Maxime Deforet, Kerry E. Boyle, Rayees Rahman, Raymond Liang, Chinweike Okegbe, Lars E. P. Dietrich, Weigang Qiu, Joao B. Xavier

Publications and Research

Bacteria of many species rely on a simple molecule, the intracellular secondary messenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to make a vital choice: whether to stay in one place and form a biofilm, or to leave it in search of better conditions. The c-di-GMP network has a bow-tie shaped architecture that integrates many signals from the outside worldÐthe input stimuliÐinto intracellular c-di-GMP levels that then regulate genes for biofilm formation or for swarming motilityÐthe output phenotypes. How does the `uninformed' process of evolution produce a network with the right input/output association and enable bacteria to make the right choice? Inspired …

Comparing Social Science And Computer Science Workflow Processes For Studying Group Interactions, Joseph A. Allen, Colin Fisher, Mohamed Chetouani, Ming Ming Chiu, Hatice Gunes, Marc Mehu, Hayley Hung

Psychology Faculty Publications

In this article, a team of authors from the Geeks and Groupies workshop, in Leiden, the Netherlands, compare prototypical approaches to studying group interaction in social science and computer science disciplines, which we call workflows. To help social and computer science scholars understand and manage these differences, we organize workflow into three major stages: research design, data collection, and analysis. For each stage, we offer a brief overview on how scholars from each discipline work. We then compare those approaches and identify potential synergies and challenges. We conclude our article by discussing potential directions for more integrated and mutually beneficial …

Prediction Of Binding Mode Of Secondary Metabolites In Apium Graveolens To Bcl-2, Kee Pei Shan, Nyi Mekar Saptarini, Jutti Levita

Pharmacology and Clinical Pharmacy Research

Developing new cytotoxic agent which has minimal effect against normal cell is required
to reduce the side effects obtained from the existing chemotherapy agents. Celery (Apium
graveolens) showed several pharmacology activities, including anti-cancer. This study was
conducted to predict and visualize the binding mode of ten secondary metabolites in A. graveolens,
i.e., apigenin, caffeic acid, kaempferol, limonene, shikimic acid, chlorogenic acid,
ascorbic acid, quercetin, eugenol and ferulic acid against Bcl-2. Navitoclax was employed as
reference. Molecular dokcing simulation was performed using AutoDoc Vina v.1.5.6. The
results showed that the interaction enery (Ei) ranged from -4.20 to -6.01 kcal/mol, whereas
inhibition …

Stormwater Capture Via Green Infrastructure In The Plaster Creek Watershed, Skyler Fish, Ben Johnson, Deanna Geelhoed, David P. Warners

Student Papers and Reports

No abstract provided.

Acute Toxicity Of Ethanol Extract Of Polygonum Pulchrum Blume Using Brine Shrimp Lethality Test Method, Asman Sadino, Idin Sahidin, Wahyuni Wahyuni

Pharmacology and Clinical Pharmacy Research

The potential toxicity effect presents in the medicinal plants is important to be identified for
the safety assurance. Accute toxicity study is an initial step in the drug safety assurance test.
Thus, the aim of this study is to identify the potential acute toxicity of roots, stems, leaves,
and flowers ethanol extracts of bamboo bamboo plants (Polygonum pulchrum Blume). This
study used brine shrimp lethality test (BSLT) method. The total number of larvae used in
each concentrations in three times replications was 330 larvae. Each group was given consecutively
roots, stems, leaves and flowers ethanol extracts of P. pulchrum Blume …

Assessment Of Plasma Selenium-Binding Protein-1 Level In Geriatric Population, Anisa F. Dewi, Lazuardhi Dwipa, Ronny Lesmana

Pharmacology and Clinical Pharmacy Research

Geriatric physiologically undergoes aging process that can cause decreasing cell function
and increasing risk of degenerative diseases caused by the accumulation of reactive oxygen
species (ROS) in the body. Selenium (Se) is an antioxidant, which is needed for maintaining
the balance of ROS. The aim of this study was to observe the selenium-binding protein
(SELENBP1) level in relation with the geriatric patients charcateristics including sex, age,
body mass index (BMI), activity of daily living (ADL), instrumental activity of daily living
(IADL), cognitive function, nutrition, depression, and insomnia status. The study used
cross-sectional quantitative descriptive study design on 14 geriatric patients …