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Aggression, Impulsivity, And Symptom Severity: An Examination Of Risk Factors For Violent Behaviors, Melissa Charfadi

Theses and Dissertations

This study sought to explore the relationship between psychopathology, aggression, and impulsivity. Two hypotheses were derived from the existing scientific literature: First, as a validity check, we anticipated that levels of psychopathology would be related to both aggression and impulsivity (as previously reported data suggests). Second, we anticipated that impulsivity would moderate the relationship between overall symptom severity and aggression. Finally, we constructed exploratory regression models to examine the contribution of specific types of impulsivity in the prediction of specific acts of aggression across BSI symptom groupings. Data was collected using Rowan University undergraduate students that completed an in-person battery …

Analysis On The Pattern Of Using The Service Of Removable Partial Denture Making In A Dental Laboratory In Surabaya, Okti Setyowati, Endang Kusdarjanti

Folia Medica Indonesiana

The making of removable denture is performed by a dental laboratory. To facilitate the identification, according to Kennedy classification, classes are divided onto groups, the Kennedy class I, II, III and IV. To suit with the needs of the dental laboratory tasks commonly done, priority are necessary for common cases and should to be taught to students of Dental Health Technology Diploma. In Surabaya, research of various cases of removable partial denture with the various Kennedy classifications has never been done before. This study was to analyze the pattern of service for the removable partial denture manufacture in dental laboratory …

Week Of August 14, 2017, New York Medical College

InTouch

• The School of Medicine Class of 2021 Joins the College Community
• Center for Long-Term Care Welcomes Notable Physiotherapist and Philanthropist for Special Presentation
• GSBMS Welcomes New Students
• HSL Hosts Talk on the Health of the First President

Novel Influences Of Il-10 On Cns Inflammation Revealed By Integrated Analyses Of Cytokine Networks And Microglial Morphology., Warren D. Anderson, Andrew D. Greenhalgh, Aditya Takwale, Samuel David, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Coordinated interactions between cytokine signaling and morphological dynamics of microglial cells regulate neuroinflammation in CNS injury and disease. We found that pro-inflammatory cytokine gene expression in vivo showed a pronounced recovery following systemic LPS. We performed a novel multivariate analysis of microglial morphology and identified changes in specific morphological properties of microglia that matched the expression dynamics of pro-inflammatory cytokine TNFα. The adaptive recovery kinetics of TNFα expression and microglial soma size showed comparable profiles and dependence on anti-inflammatory cytokine IL-10 expression. The recovery of cytokine variations and microglial morphology responses to inflammation were negatively regulated by IL-10. Our novel …

Effect Of Sandblasting Time On The Roughness Of The Metal Cobalt-Chromium (Co-Cr) During Denture Metal Framework Production, Endang Kusdarjanti, Dwiyanti Feriana R, Eny Inayati

Folia Medica Indonesiana

One of the stages of manufacture of denture metal framework that is sandblasting, ie cleaning the remnants of investment material after metal casting process and remnants of metal oxide on the surface. After fitting in the master model, then the metal framework dentures do sandblasting again until smooth before elektropolishing. The tools used are sandblaster, material Al2O3 (aluminum oxide) size of 250 lm. The time it takes about 1 minute, but the time of 1 minute when applied to student practicum D3 is still not clean and there are still remnants of planting material castings and metal oxide on the …

Analysis Of Changes In The Serum Level Nt-Probnp After Ace Inhibitors Therapy In Patients With Heart Failure, Halla Hisan Hartoto, Bambang Subakti Zulkarnain, Muhammad Aminuddin

Folia Medica Indonesiana

BNP secreted by left ventricle as response to wall stress in patient with heart failure. Elevated concentration of NT-pro-BNP correlate with severity of heart failure across all stages of the condition and left ventricle ejection fraction in patient. Several clinical trials have demonstrated that neurohormonal modulation on the RAAS decreases NT-proBNP level and results in favorable outcomes. One of the drug used for blocked RAAS system is ACE inhibitor, decrease of NT-proBNP level show response to therapy include therapy with ACE inhibitors. To analize changes in the levels serum NT-proBNP levels after ace inhibitor therapy in patients with heart failure …

Antibiogram Study And Antibiotic Use Evaluation Using Gyssen Method In Patients With Diabetic Foot, Umul Fadlilah, Didik Hasmono, Yudi Agung Wibisono, Mia Melinda

Folia Medica Indonesiana

Foot infection is a common and serious problem in people with diabetes, which require proper management (diagnostic and therapeutic approaches) that can be cured. Empiric antibiotic regimen should be based on clinical data and bacteria pattern that are available, but definitive therapy should be based on the results of the infected tissue culture. The selection of initial antibiotic therapy was difficult and unwise use can lead to antibiotic-resistant. Evaluation is needed for using antibiotics to benefit wisely. The aim of this research is to analyzed the pattern of bacteria in diabetic foot and to its sensitivity test to antibiotics, analyze …

In Vitro Fertility Test Of Human Spermatozoa Membrane Protein Fertilin Beta Antibody In Mice (Mus Musculus Balb/C) As Immunocontraceptive Candidate, Reny I'Tishom, Doddy M Soebadi, Aucky Hinting, Hamdani Lunardhi, Rina Yudiwati

Folia Medica Indonesiana

One of the materials as potential candidates immunocontraception material is spermatozoa. Fertilin beta is spermatozoa membrane protein and is found only in mature spermatozoa and ejaculate, which serves as an adhesion molecule. Spermatozoa membrane protein that is used as an ingredient immunocontraception candidate, must have specific criteria that the specificity of spermatozoa, the role of antigen in the fertilization process, which includes the formation of immunogenicity sufficient antibody response has the potential to block fertilization. Antibodies against spermatozoa affect the stages before fertilization of the reproductive process and can hinder the development of the embryo after fertilization. Until now very …

Correlation Between Blood Glucose Level And Thinking Concentration, Putri Itonami Gaol Marbun, Tengku Helvi Mardiani

Folia Medica Indonesiana

Cognition function specifically about thinking concentration has not much yet been studied. Society view shown that glucose has role thinking quality. Few studies shown that glucose has role in specific memory quality but not in complex thinking. This study purpose to see correlation between blood glucose level with thinking concentration before eating (preprandial), after eating (postprandial), and the effect of blood glucose rise on thinking concentration. Subjects that accomplished study's requirement were recruited until forty six people and were followed within thirty minutes. Blood Glucose level was measured by glucose meter at initial admission, thinking concentration were measured with trail …

The Effect Of Long Term Administration Of Glucocorticoid To Bone Lining Cells Apoptosis, Gadis Meinar Sari

Folia Medica Indonesiana

Glucocorticoid is widely used in medical treatment as an immune system or an inflammation therapy. However its long term administration can cause life-threatening side effects. One of them is bone mass loss which increases the risk of bone fractures in the long-term use. Bone lining cells derived from mesenchymal stem cells, which serve as a backup cell bone-forming osteoblasts. Glucocorticoids acting directly on osteoblasts, bone lining cells when reduced due to increased apoptosis, the reserve cells to bone formation will be decreased. The aim of this study was to count the amount of apoptotic bone lining cells after long term …

Nt-Probnp Level Changes After Combination Therapy With Bisoprolol And Ace-Inhibitor In Patient With Heart Failure, Reine Risa Risthanti, Muhammad Aminuddin, Suharjono Suharjono

Folia Medica Indonesiana

Heart failure (HF) is the final common stage of many diseases of the heart. NT-proBNP levels are increased in HF and correlate well with ventricular wall stress and severity of HF. Combination therapy with Bisoprolol and ACE-inhibitor decreases NT-proBNP level in patient with HF. The use of Bisoprolol as a combination with ACE-inhibitor is still dominate in outpatient setting at Dr. Soetomo teaching hospital. The objective of this study is to analyze NT-proBNP level changes as an indicator in cardiac function after combination therapy with Bisoprolol and ACE-inhibitor in patient with HF.Methods: This study was prospective, observational and conducted in …

Phosphatidylglycerol Study As Fetal Lung Maturation Parameter After Dexamethasone Administration For Women At Risk Of Preterm Birth, Rizal Umar Rahmadani, Agus Sulistyono, Yulistiani Yulistiani, Muhammad Yahya

Folia Medica Indonesiana

Phosphatidylglycerol is an important indicator of fetal lung maturation, which plays a role in stabilizing surfactant lipoprotein complex. Corticosteroid antenatal can stimulate the synthesis of pulmonary surfactant in infants with preterm birth. The objective of this study is to examine the phosphatidylglycerol levels as fetal lung maturation parameter after dexamethasone administration in women with preterm birth compared to L/S ratio parameter. This study was prospective longitudinal (cohort). The samples were pregnant women with preterm birth risk at 28-34 weeks gestation getting the therapy of antenatal dexamethasone 6 mg IM every 12 hours given 4 times in 48 hours. The samples …

Analysis Of Change In Nt-Probnp After Angiotensin Receptor Blocker (Arb) Therapy In Patient With Heart Failure, Intan Kusuma Dewi, Muhammad Aminuddin, Bambang Subakti Zulkarnain

Folia Medica Indonesiana

NT-proBNP is an inactive fragment of BNP secreted by stretched ventricle as response to wall stress in patients with heart failure. As a specific cardiac marker, elevated NT-proBNP correlates well with heart failure severity. The principle of heart failure therapy is modulation on neurohormonal activation. ARB can modulate neurohormon on RAA system, that result in decreasing NT-proBNP level and favorable outcomes. Reduction in NT-proBNP more than biologic variability (> 25%) shows a therapy response.This study was to analyze change of NT-proBNP after ARB therapy in ambulatory HF patients. This observational prospective study was carried from September to December 2015. Blood …

Metalloproteases Of The Inner Mitochondrial Membrane, Roman M. Levytskyy, Iryna Bohovych, Oleh Khalimonchuk

Department of Biochemistry: Faculty Publications

The inner mitochondrial membrane (IM) is among most protein-rich cellular compartments. The metastable IM sub-proteome where the concentration of proteins is approaching oversaturation creates a challenging protein folding environment with high probability for protein malfunction or aggregation. Failure to maintain protein homeostasis in such a setting can impair functional integrity of the mitochondria and drive clinical manifestations. The IM is equipped with a series of highly conserved, proteolytic complexes dedicated to the maintenance of normal protein homeostasis within this mitochondrial sub-compartment. Particularly important is a group of membrane-anchored metallopeptidases commonly known as m-AAA and i-AAA proteases, and the ATP-independent Oma1 …

Alternative Healthy Eating Index 2010, Dietary Inflammatory Index And Risk Of Mortality: Results From The Whitehall Ii Cohort Study And Meta-Analysis Of Previous Dietary Inflammatory Index And Mortality Studies, Nitin Shivappa, James R. Hébert, Mika Kivimaki, Tasnime Akbaraly

Faculty Publications

We aimed to examine the association between the Alternative Healthy Eating Index updated in 2010 (AHEI-2010), the Dietary Inflammatory Index (DIITM) and risk of mortality in the Whitehall II study. We also conducted a meta-analysis on the DII-based results from previous studies to summarise the overall evidence. Data on dietary behaviour assessed by self-administered repeated FFQ and on mortality status were available for 7627 participants from the Whitehall II cohort. Cox proportional hazards regression models were performed to assess the association between cumulative average of AHEI-2010 and DII scores and mortality risk. During 22 years of follow-up, 1001 participants died …

Potassium Monitoring In Heart Failure Patients Receiving Combined Therapy Of Captopril And Furosemide, Hubby Hubby, Suharjono Suharjono, Zaenab Djafar

Folia Medica Indonesiana

In the treatment of heart failure is recommended the use of a combination of ACEI (captopril) with diuretics (furosemide), ACEI has the side effect of hyperkalemia 10-38% in hospitalized patients and 10% in outpatients, is increased in patients with renal failure and diabetes mellitus, the use diuretics occur hypokalemia 5-20% in outpatients. Hyperkalemia and hypokalemia both should be avoided in heart failure patients, because it can cause cardiac conduction disorders such as cardiac arrhythmias This study aims to monitor levels of potassium in the use of combination therapy with furosemide captopril in heart failure patients. The study was conducted using …

Effect Of Cognitive Behavioral Therapy For Serotonin Level, Depression Score And Quality Of Life In Cervical Cancer Patients, Soetrisno Soetrisno, Sri Sulistyowati, Supriyadi Hari Respati, Muhamad Nasrudin

Folia Medica Indonesiana

Cervical cancer is the most common cause of death among gynaecological neoplasms. Management of advanced cervical cancer currently has not been able to improve the prognosis. Standard intervention therapy, chemotherapy and radiotherapy, as well as the emerging pain could lead to psychological stress till depression, thus reduce patients' quality of life. CBT for psychological stress and depression is expected to improve the fruitfulness of standard therapy. Serotonin is a neurotransmitter which plays a role in the patophysiology of depression. The aim of this study is to analyze the effect of cognitive behavioral therapy on serotonin level, depression score and quality …

Seladelpar (Mbx-8025), A Selective Ppar-Δ Agonist, In Patients With Primary Biliary Cholangitis With An Inadequate Response To Ursodeoxycholic Acid: A Double-Blind, Randomised, Placebo-Controlled, Phase 2, Proof-Of-Concept Study., David Jones, Pol F. Boudes, Mark G. Swain, Christopher L. Bowlus, Michael R. Galambos, Bruce R. Bacon, Yvonne Doerffel, Norman Gitlin, Stuart C. Gordon, Joseph A. Odin, David Sheridan, Markus Alexander Wörns, Virginia Clark, Linsey Corless, Heinz Hartmann, Mark E. Jonas, Andreas E. Kremer, George F. Mells, Peter Buggisch, Bradley L. Freilich, Cynthia Levy, John M. Vierling, David E. Bernstein, Marek Hartleb, Ewa Janczewska, Fedja Rochling, Hemant Shah, Mitchell L. Shiffman, John H. Smith, Yun Jung Choi, Alexandra Steinberg, Monika Varga, Harinder Chera, Robert Martin, Charles A. Mcwherter, Gideon M. Hirschfield

Peninsula Medical School

BACKGROUND: Many patients with primary biliary cholangitis have an inadequate response to first-line therapy with ursodeoxycholic acid. Seladelpar is a potent, selective agonist for the peroxisome proliferator-activated receptor-delta (PPAR-δ), which is implicated in bile acid homoeostasis. This first-in-class study evaluated the anti-cholestatic effects and safety of seladelpar in patients with an inadequate response to ursodeoxycholic acid. METHODS: The study was a 12-week, double-blind, placebo-controlled, phase 2 trial of patients with alkaline phosphatase of at least 1·67 times the upper limit of normal (ULN) despite treatment with ursodeoxycholic acid. Patients, recruited at 29 sites in North America and Europe, were randomly …

The Role Of The Clinical Nurse Leader In Reintroducing And Sustaining A Successful Cancer Risk Assessment Program In A Community Hospital Setting, Tiffany Gishizky

Master's Projects and Capstones

Abstract

The goal of implementing a comprehensive cancer risk assessment (CRA) program prompted the evaluation of a community-based breast center microsystem and previous CRA program for feasibility and sustainability. The development of a value proposition by the Clinical Nurse Leader student highlights the role in the advancement of the nursing profession as an interdisciplinary leader. Review of current literature facilitated development of program structure and identification of downstream revenue sources. Data analysis includes historical patient volume, screening and procedural reimbursement rates, population statistics and organization market share, and program financial impacts. Data synthesis reveals a CRA program demonstrates potential revenue …

Analysis Of Earphone Swab Mitochondrial Dna As An Alternative Material For Identification Examination, Ahmad Yudianto, Yeti Eka Sispitasri, Nola Margaret

Folia Medica Indonesiana

Identification include fingerprint, property, medical, dental, serologic and exclusion methods. In the development, identification methods led to molecular forensics, a new field of science evolving since the 1980s, known as DNA fingerprinting. Specimens widely used in DNA assay for identification are blood spots/bloods, semen spots, vaginal swabs, buccal swabs and bones. In addition to these specimens, the last objects often used by the perpetrators/victims can be used, such as hearing aids (headsets/earphones). In its use, earphones are attached to the outer ear skin; thus, the earwax is suspected to adhere to the device. To date, in Indonesia personal identification is …

Provision Of Arak Bali Reduces Spermatozoa Quality Of White Rats (Rattus Norvegicus), Ni Wayan Sukma Antari, Alfiah Hayati, Dwi Winarni

Folia Medica Indonesiana

This study aimed to determine the effect of arak bali on the quality of spermatozoa include morphology, motility, viability, membrane integrity of spermatozoa rat (Rattus norvegicus). The study was conducted in two phases: the first phase of the deployment of questionnaires conducted in five districts in Bali to determine the type and frequency of arak bali consumption and phase II made arak bali giving treatment in experimental animals. This study used 24 male rats (170-200 grams), divided into four groups: one control and three treatments (by arak bali containing 40% alcohol as much as 0.1 and 0.5 mL and 0.1 …

The Effects Of Banana Stem (Musa Paradisiaca Var. Sapientum) Extract On Histopathologic Gastric Of Rats Induced By Indometachin, Rochmah Kurnijasanti, Arninda Alfiani Putri

Folia Medica Indonesiana

This research aims to find out the administration effect of Ambon banana stem extract (Musa paradisiaca var. sapientum) to prevent gastric damage and observe histopathology of rat's gastric induced by indomethacin. This research used 30 male rats age 8-12 week having 150 gram weight. They were selected randomly and divided into five groups. Negative control (K-) was given 0.5 ml CMC Na 0.5 % for 9 days and 0.5 ml corn oil was given on 10th. Positive control (K+) was given 0.5 ml CMC Na 0.5% for 9 days and then given Indomethacin emultion 5 mg/0.5 ml/150 g BW once …

Dna Isolation From Human Urine Stain As An Alternative Material For Personal Identification Examination, Ahmad Yudianto, Yeti Eka Sispitasari

Folia Medica Indonesiana

Accurate determination of personal identity is crucial for an investigation since any inaccuracy may lead to fatal consequences in the judicial process. Identification through DNA analysis involves somatic chromosomes and mtDNA. Each part of the human body can be taken as a specimen since every nucleated cell in the body of an individual has identical DNA sequence. To date, samples for identification through DNA analysis are obtained from blood stains, semen stains, bones, vaginal swab, buccal swab etc. In certain cases, urine stains on the clothing have frequently been overlooked. So far, personal identification through DNA analysis by the use …

The Profile Of The Level Of Endogenous No In Migraine Sufferers, Arman Yurisaldi Saleh, Hasan Machfoed, Kuntoro Kuntoro

Folia Medica Indonesiana

Migraine is a health problem which had big impact. A neurochemistry change in the dura, that is the increase of the amount of nitrite oxide, originated from an excessive NOS (inducible NOS) activation during ictal. Some researchers assume NO as a main cause of the pain intensity in ictal. Migraine diagnosis is guided by the International Headache Society. Hopefully, this examination can be used as a more objective diagnosis in the future. Methode of this research is descriptive analytic. This study to find the level of endogenous exhaled NO on 91 subject, consisting of 30 normal people, 31 interictal, 30 …

Approval Of New Core Curriculum, Michelle Cawthorn

Faculty Senate: Index

No abstract provided.

A Computational Model Of The Evolution Of Antipredator Behavior In Situations With Temporal Variation Of Danger Using Simulated Robots, D Pacella, M Ponticorvo, O Gigliotta, O Miglino

School of Engineering, Computing and Mathematics

The threat-sensitive predator avoidance hypothesis states that preys are able to assess the level of danger of the environment by using direct and in-direct predator cues. The existence of a neural system which determines this ability has been studied in many animal species like minnows, mosquitoes and wood frogs. What is still under debate is the role of evolution and learning for the emergence of this assessment system. We propose a bio-inspired computing model of how risk management can arise as a result of both factors and prove its impact on fitness in simulated robotic agents equipped with recurrent neural …

Synthesizing Human Actions With Emotion, Mousumi Deb

Electronic Theses and Dissertations Archive

Realistic synthesis of human actions is a challenging problem. This thesis investigates the problem of synthesizing actions, with individual variability, under different emotions. Current actions/gesture synthesis, understanding and recognition models do not provide a general framework for synthesizing an extensive range of actions over a large range of emotions.The literature on spectral style transfer provides a plethora of viable approaches for transferring the style of action learned from one individual to another. Our idea is to consider an emotion as a style then use a style transfer algorithm for transferring an emotion from one action to another. This allows us …

Ecopath With Ecosim Model Of The West Florida Shelf Representing 1980 For Harmful Algal Bloom Simulations, Cameron Ainsworth, Alisha Gray

C-IMAGE data

This is an Ecopath with Ecosim model of the West Florida Shelf. It is based on a model constructed by Mahmoudi (unpublished data) (see Okey et al. 2004 for an application) and later modified Gray et al. 2013 to incorporate additional exploited and non-exploited species and life stages known to be sensitive to harmful algal blooms (HABs). To incorporate HABs an additional (pseudo) fishing fleet is added into the model to provide a red tide mortality driver on adult fish and invertebrates. Biomass caught by this fleet is immediately cycled into the detritus pool, and thus nutrients from killed fish …

Working On The Wayne | Snazzy Snakes, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Linking Kindling To Increased Glutamate Release In The Dentate Gyrus Of The Hippocampus Through The Stxbp5/Tomosyn-1 Gene, Seth R. Batten, Elena A. Matveeva, Sidney W. Whiteheart, Thomas C. Vanaman, Greg A. Gerhardt, John T. Slevin

Psychology Faculty Publications

Introduction: In kindling, repeated electrical stimulation of certain brain areas causes progressive and permanent intensification of epileptiform activity resulting in generalized seizures. We focused on the role(s) of glutamate and a negative regulator of glutamate release, STXBP5/tomosyn-1, in kindling.

Methods: Stimulating electrodes were implanted in the amygdala and progression to two successive Racine stage 5 seizures was measured in wild-type and STXBP5/tomosyn-1^−/− (Tom^−/−) animals. Glutamate release measurements were performed in distinct brain regions using a glutamate-selective microelectrode array (MEA).

Results: Naïve Tom^−/− mice had significant increases in KCl-evoked glutamate release compared to naïve wild type as …