Digital Commons Network^™

A Reflection On Some Key Pedagogical Competencies, Valuable To The Role Of The Medical Educator, A Houldsworth

School of Health Professions

Powerpoint presentation delivered to academics in RAKUMHS

Student Movement - Issue 6, Andrews University

Student Movement v. 102 (2017-2018)

Student Movement, Issue 6, 2017

Common Core State Standards And Text Complexity: An Invitation To Learn Language In Stem Disciplines Using A Range Of Quality Literature, Rebecca M. Giles, Leah Kinniburgh

The Journal of Balanced Literacy Research and Instruction

The Common Core State Standards (CCSS) emphasize literacy learning within history/social studies, science, and technical subjects making students’ reading, writing, and language development every teacher’s concern, regardless of the discipline being taught. Books related to science, technology, engineering, and mathematics (STEM) can enhance students’ knowledge of key terms and concepts as they are revealed in authentic contexts. Students who often struggle harder to understand advanced vocabulary embedded in stories or in difficult, yet interestingly presented nonfiction gain an increased print vocabulary by reading quality STEM-aligned literature selections that exhibit the characteristics of complexity and richness of language advocated by CCSS. …

Morphodynamics Of Atolls, Reef Flats, And The Islands Atop Them, Andrew Ashton

Sustainability Seminar Series

The atolls that dot the tropical oceans of (primarily) the Pacific and Indian Oceans contain shallow and emergent coastal environments that often comprise the only subaerial, inhabitable land of many island chains and island nations. Created foremost by calcifying organisms, and composed of both biogenic rocky substrate and detrital sediment, these shallow environments are shaped by waves, currents, and tides. The low-lying, geomorphically active reef islands sitting atop of atolls face considerable hazards from climate change. I will present a series of recent and ongoing research projects addressing the formation mechanisms and potential climate change response of coastal atoll environments, …

#Textbookbroke: What's The Most You've Spent On Textbooks In One Semester?, Scholarly Communications

Open Access Week at Gettysburg College

Throughout Open Access Week 2017, a large graph hung on the main floor of Musselman Library where students shared how much they spent on textbooks in a semester. Under the title of "#textbookbroke," this crowdsourced data was displayed to the campus community as it was gathered over the course of the week.

Harnessing The Data Revolution, Chaitan Baru

Commonwealth Computational Summit

Harnessing Data for 21st Century Science and Engineering (aka Harnessing the Data Revolution, HDR) is one of NSF's six "Big Research Ideas," aimed at supporting fundamental research in data science and engineering; developing a cohesive, federated approach to the research data infrastructure needed to power this revolution; and developing of a 21st-century data-capable workforce. HDR will enable new modes of data-driven discovery allowing researchers to ask and answer new questions in frontier science and engineering, generate new knowledge and understanding by working with domain experts, and accelerate discovery and innovation. This initiative builds on NSF's history of data science investments. …

Sixth Brics Summit-Fortaleza Declaration

Law and Business Review of the Americas

No abstract provided.

Latinx And Caucasian Elementary School Children’S Knowledge Of And Interest In Engineering Activities, Gamze Ozogul, Cindy Faith Miller, Martin Reisslein

Journal of Pre-College Engineering Education Research (J-PEER)

Ethnic minorities, such as Latinx people of Hispanic or Latino origin, and women earn fewer engineering degrees than Caucasians and men. With shifting population dynamics and high demands for a technically qualified workforce, it is important to achieve broad participation in the engineering workforce by all ethnicities and both genders. Previous research has examined the knowledge of and interest in engineering among students in grades five and higher. In contrast, the present study examined elementary school students in grades K–5. The study found that older students in grades 4 and 5 had both greater knowledge of engineering occupational activities and …

The House Of Lords And The Discontinuation Of Artificial Nutrition And Hydration: An Ethical Analysis Of The Tony Bland Case, Moira M. Mcqueen, James L. Walsh

The Catholic Lawyer

No abstract provided.

Analysis Of Complex Vertebrate Genomes: Computational Challenges And Solutions, Jeramiah J. Smith

Commonwealth Computational Summit

No abstract provided.

Accurate And Scalable Query Over Large Rna‐Seq Experiments, Jinze Liu

Commonwealth Computational Summit

No abstract provided.

Integrative Computational Modeling For Developing Means To Manipulate Biological Cells And For Solving Complex Engineering Problems, Yu Zhao, Guigen Zhang

Commonwealth Computational Summit

A brief discussion on reductive vs integrative investigation

A case study: how integrative computational modeling helps advance the understanding and application of dielectrophoresis (DEP) in various situations

Other applications in advancing the design and development of nanopore, medical devices, novel materials, actuation devices, and coupled spectroscopic techniques, etc.

Registration And Grouping Algorithms In Protein Nmr Derived Peak Lists And Their Application In Protein Nmr Reference Correction, Andrey Smelter, Xi Chen, Eric C. Rouchka, Hunter N. B. Moseley

Commonwealth Computational Summit

Nuclear magnetic resonance spectroscopy of proteins (protein NMR) is a powerful analytical technique for studying structure and dynamics of proteins. Almost all aspects of protein NMR have been accelerated by the development of software tools that enable the analysis of NMR spectral data and its utilization in studying protein structure and dynamics. This includes software for raw NMR processing, spectral visualization, protein resonance assignment, and structure determination. However, full automation of protein NMR data analysis is still a work in progress and data analysis still requires an expert NMR spectroscopist utilizing an array of software tools.

While manual resonance assignment …

The Lamprey Genome: Illuminating Genomic Change Across Eons And Embryogenesis, Jeramiah J. Smith, Courtney K. M. Waterbury, Melissa C. Keinath, Cody B. Saraceno, Vladimir A. Timoshevskiy, Nataliya Y. Timoshevskaya

Commonwealth Computational Summit

The lamprey genome provides unique insights into both the deep evolutionary history of vertebrate genomes and the maintenance of genome structure/integrity over development. The lamprey lineage diverged from all other vertebrates approximately 500 million years ago. As such, comparisons between lamprey and other vertebrates permit reconstruction of ancient duplication and rearrangement events that defined the fundamental architecture and gene content of all extant vertebrate genomes. Lamprey also undergoes programmatic changes genome structure that result in the physical elimination of ~20% of its genomic DNA (~0.5Gb from a ~2 Gb genome) from all somatic cell lineages during early embryonic development. Here, …

Structure-Based Drug Discovery: Computational Virtual Screening, Robert C. Monsen, Lynn Deleeuw, Jon Maguire, William L. Dean, Robert D. Gray, Jonathan B. Chaires, John O. Trent

Commonwealth Computational Summit

No abstract provided.

Bio-Inspired Disaster Response Networks, Vijay K. Shah, Simone Silvestri, Sajal K. Das, Satyaki Roy

Commonwealth Computational Summit

Large-scale natural disasters (e.g., Earthquake, Hurricane) –

• Three times as many disasters between 1980 and 2016 compared to 1940-1980. (EM-DAT – The International Disaster Database)
• Since 1990, 217 million people affected each year. (The New England Journal of Medicine)

Aftermath a disaster,

• Loss of human lives and property
• Lack of food, clean drinking water, shelter etc.
• Disruption of infrastructure networks (e.g. cellular towers) and other public infrastructures (e.g. power sources) – Our focus !

Use Of Hpc To Analyze Changes In Gene Expression During Fruit Fly Spermiogenesis, Sepideh Dadkhah, Douglas A. Harrison, Jeramiah J. Smith

Commonwealth Computational Summit

In the fruit fly, Drosophila melanogaster, JAK/STAT signaling during spermiogenesis is known to play a crucial role in the maintenance of stem cells of the testis. Recent studies in our lab have shown that activation of the JAK/STAT pathway in somatic cyst cells is also required for the later stages of spermiogenesis like individualization.

The main goal of this project is to characterize the events downstream of JAK/STAT signaling in spermiogenesis and more specifically to determine the mechanism by which JAK/STAT activation regulates individualization, a later stage in spermiogenesis where 64 individual spermatids are formed from a 64-interconnected spermatid …

Aberrant Coordination Geometries Discovered In Most Abundant Metalloproteins, Sen Yao, Robert M. Flight, Eric C. Rouchka, Hunter N. B. Moseley

Commonwealth Computational Summit

Metalloproteins play crucial biochemical roles in our body and are essential across all domains of life. The structural environment around a metal ion, especially the coordination geometry (CG), is both sequentially and functionally relevant. Studies of the metalloprotein’s CG will greatly help alleviate the imbalance between the ample sequence data available and the insufficient knowledge on protein functions. Current methodologies in characterizing metalloproteins’ CG consider only previously reported CG (canonical CG) models based primarily on nonbiological chemical context. Exceptions to these canonical CG models can greatly hamper the ability to characterize metalloproteins both structurally and functionally.

Integrative Computational Modeling For Developing Means To Manipulate Biological Cells And For Solving Complex Engineering Problems, Yu Zhao, Guigen Zhang

Commonwealth Computational Summit

Computational modeling has become more widely used to guide the design of microfluidic devices for manipulating cells using Dielectrophoresis (DEP), and devise novel means for advancing the study of cellular science and engineering. Conventionally, cells are treated as volumeless points in the system, which allows study of the movement of groups of particles under the effect of field. However, this approach often neglects the distortion effect of particle on external field, as well as interactions among particles. Moreover, it ignores the complex inner structures of cell, which are the causes of distinctive cell behavior. To more accurately model the behavior …

Discovery Of Sex-Specific Regions In A Salamander Genome, Nataliya Y. Timoshevskaya, Melissa C. Keinath, Jeramiah J. Smith

Commonwealth Computational Summit

Biological Aspects:

Salamander (Ambystoma mexicanum) has a gigantic genome: ~32,000,000,000 bases (10X of size of human genome)

Sex is determined by a pair of morphologically identical chromosomes:

• ZZ in male
• ZW in female

Object:

• Find (if there are any) genomic differences between chromosomes W and Z

Workflow:

1. Sequencing and de novo assembly of the reference salamander genome
2. Alignment of short sequences from male and female genomes to the reference
3. Coverage analysis

Why Do We Care?: A Natural History Of Noddings’ Ethical Theory, Walter Jason Niedermeyer

Between the Species

Noddings’ theory of caring, which is nearing its 35^th anniversary, has failed to garner the attention of the more classical theories of ethics. This slight may be due to its relative youth, or the historical support for other constructs, but if examined through the lens of evolutionary biology, the validity of Noddings might be tested. Using recent discoveries from the emerging fields of cognitive ethology and neuroscience, I have evaluated whether there exists evolutionary underpinnings for her theory. My analysis makes it apparent that the empathy and altruism required for the practice of caring are as much a product …

Method And System For Non-Invasive Optical Blood Glucose Detection Utilizing Spectral Data Analysis, Zhi Xu

UMSL Patents

Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes at least one light source configured to strike a target area of a sample, at least one light detector positioned to receive light from the at least one light source and to generate an output signal, having a time dependent current, which is indicative of the power of light detected, and a processor configured to receive the output signal from the at least one light detector and based on the received output signal, calculate the attenuance attributable to blood …

Spring 2018 Making And Breaking Law Theme Highlights Exciting Courses, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Distinguished Professors Legacy Inspires Alumni Students, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

The Utah Statesman, October 17, 2017, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Academics: The Newsletter Of The Swosu College Of Arts And Sciences, Peter Grant

aCAdemicS: The Newsletter of the SWOSU College of Arts & Sciences

No abstract provided.

Compositions And Methods Of Modulating 15-Pgdh Activity, Sanford Markowitz, James K. V. Willson, Bruce A. Posner, Joseph Ready, Yongyou Zhang, Hsin-Hsiung Tai, Monika Antczak, Stanton Gerson, Kibeom Bae, Sung Yeun Yang, Amar Desai

Pharmaceutical Sciences Faculty Patents

Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.

Methods Of Temperature & Metabolism Reduction In Rats And Possible Influence On Human Health, Isaac R. Bailey

Chemistry and Biochemistry

Spaceflight poses unique and significant hazards; the maintenance of human health remains a large part of the National Aeronautic and Space Administration (NASA) strategic goals and work remains to be done if we wish to maintain a long-term presence in space. The effects of ionizing radiation and bone density loss are some of the primary health related problems which need to be addressed. One of the main purposes of this research is to translate aspects of thermoregulation and metabolism reduction in hibernating species to a non-hibernating species in- order to devise alternative methods of preventing DNA damage and loss of …

Daily Eastern News: October 17, 2017, Eastern Illinois University

October

No abstract provided.

Differentiation And Protective Capacity Of Virus-Specific Cd8, Vesselin T. Tomov, Olesya Palko, Chi Wai Lau, Ajinkya Pattekar, Yuhang Sun, Ralitza Tacheva, Bertram Bengsch, Sasikanth Manne, Gabriela L. Cosma, Laurence C. Eisenlohr, Timothy J. Nice, Herbert W. Virgin, E. John Wherry

Department of Microbiology and Immunology Faculty Papers

Noroviruses can establish chronic infections with active viral shedding in healthy humans but whether persistence is associated with adaptive immune dysfunction is unknown. We used genetically engineered strains of mouse norovirus (MNV) to investigate CD8⁺ T cell differentiation during chronic infection. We found that chronic infection drove MNV-specific tissue-resident memory (Trm) CD8⁺ T cells to a differentiation state resembling inflationary effector responses against latent cytomegalovirus with only limited evidence of exhaustion. These MNV-specific Trm cells remained highly functional yet appeared ignorant of ongoing viral replication. Pre-existing MNV-specific Trm cells provided partial protection against chronic infection but largely ceased …