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Identification Of A Novel Synaptic Protein, Tmtc3, Involved In Periventricular Nodular Heterotopia With Intellectual Disability And Epilepsy, Sali M K Farhan, Kevin C J Nixon, Michelle Everest, Tara N Edwards, Shirley Long, Dmitri Segal, Maria J Knip, Heleen H Arts, Rana Chakrabarti, Jian Wang, John F Robinson, Donald Lee, Seyed M Mirsattari, C Anthony Rupar, Victoria M Siu, Forge Canada Consortium, Michael O Poulter, Robert A Hegele, Jamie M Kramer

Paediatrics Publications

Defects in neuronal migration cause brain malformations, which are associated with intellectual disability (ID) and epilepsy. Using exome sequencing, we identified compound heterozygous variants (p.Arg71His and p. Leu729ThrfsTer6) in TMTC3, encoding transmembrane and tetratricopeptide repeat containing 3, in four siblings with nocturnal seizures and ID. Three of the four siblings have periventricular nodular heterotopia (PVNH), a common brain malformation caused by failure of neurons to migrate from the ventricular zone to the cortex. Expression analysis using patient-derived cells confirmed reduced TMTC3 transcript levels and loss of the TMTC3 protein compared to parental and control cells. As TMTC3 function is currently …

Effect Of Bm-Hpme® Free Protein On Hbm-Mscs In Benchtop Bioreactor With Microcarriers, Adam Talbot

Biology Posters

Mesenchymal stem cell (MSC)-based therapies have great potential for treating many age-related diseases. When harvested from human bone marrow (hBM), these cells are relatively scarce and thus is is necessary for the cells to be expanded to achieve the necessary numbers needed for any therapeutic application and for many research applications. In order for the potential of MSCs to be unlocked, a strategy must be developed to expand these cells in the most efficient and effective way possible. Here we present a method to expand MSCs in a benchtop bioreactor with microcarriers and quantify the effect of the addition of …

Importance Of Seed As An Inoculum Source For High Plains Virus In Sweet Corn, Brooke Olson, Claudia Nischwitz

Biology Posters

High Plains Virus (HPV) is found in small grains and corn and is commonly transmitted by the wheat curl mite. In 2016, a local farmer had a high incidence of HPV in all of his sweet corn in three different locations. However no mites were found. Drone imagery was taken of the field and showed a pattern of infected corn plants that indicated that the virus was seed borne. Yield loss was an estimated 50% for the field. Seed transmission of HPV in corn has been considered unimportant in the past due to low percentage of infection (Forster et al. …

Setting The Mood: Background Color And Guppy Mate Choice, Haley Schmid, Michael Thompson, Easton Smith, Kim Sullivan

Biology Posters

▪ There are two prevalent forms of sexual selection in the animals:Male-Male Competition and Female Choice

▪ Guppies (Poecilia reticulata) have been shown to demonstrate Female Choice

▪ Environmental factors, such as background color, have been shown to affect female interest in specific males

▪ Guppies tend to show interest in the color orange and we predicted that females would show a preference for males on an orange background

In The Organization’S Shadow: How Individual Behavior Is Shaped By Organizational Leakage, Matthew E. Brashears, Michael Genkin, Chan S. Suh

Sociology Faculty Publications and Presentations

Individuals who join an organization often adopt its characteristic behaviors, but does the same effect extend to nearby nonmembers, and is this process impeded or enhanced by the competition between organizations? This article argues that organizations influence the behavior of both members and proximate nonmembers in a process we term “organizational leakage” and that competition between organizations moderates the impact of any one of them on individual behavior. This article finds, using the Add Health data, that an individual’s location in an organizational ecology is an important predictor of his or her behavior, even while controlling for other factors, including …

Suppurative Complications Of Acute Hematogenous Osteomyelitis In Children, Jennifer J. Johnston, Cristina Murray-Krezan, Walter N. Dehority

Pediatrics Research and Scholarship

We carried out a case-control study in children with acute hematogenous osteomyelitis (AHO) with and without suppurative complications discharged from our institution over an 11-year period to test the hypothesis that abscess formation was associated with a delayed presentation to care. Of 102 children with AHO, 54 abscesses were documented in 46 patients (25 bone, 29 muscle). A delay in presentation was not associated with abscess formation (6.5 vs. 5.0 days, P=0.26). Overall, 78% of all bone abscesses were visible on initial MRI. Consistent use of MRI at presentation may identify children with suppurative complications of AHO.

An Optimal Milk Production Model Selection And Configuration System For Dairy Cows, Fan Zhang

PhDs

Milk production forecasting in the dairy industry has been an independent research topic since the early 20th century. The accurate prediction of milk yield can benefit both the processor (creameries) and the producer (dairy farmer) through developing short-term production schedules, planning long-term road maps, facilitating trade and investment in the dairy industry, improving business operations, optimising the existing infrastructure of the dairy industry, and reducing operating costs. Additionally, due to the innate characteristics of the milk production process, the accurate prediction of milk yield has been a challenging issue in the dairy industry. With the abolishment of EU milk quotas …

Biological Sciences Graduate Senate New Fossil Discoveries From The End Of The Age Of Dinosaurs In Antarctica, Dec. 1, Ohio University College Of Arts & Sciences

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No abstract provided.

Scientific Illustration Vesna Jovanovics Drawings And Paintings, Nov. 9, Ohio University College Of Arts & Sciences

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No abstract provided.

Chemistry Colloquium | Multiplexed Tracking And Imaging Of Nanoparticles In Biological Samples Using Mass Spectrometry, Nov. 20, Ohio University College Of Arts & Sciences

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No abstract provided.

Geology Colloquium | Tracking Ecological Change Through The Anthropocene And Beyond, Nov. 3, Ohio University College Of Arts & Sciences

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No abstract provided.

Ecolunch | Populations And Movements Of Little Brown Myotis In Yellowstone National Park, Nov. 15, Ohio University College Of Arts & Sciences

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No abstract provided.

Invited Speaker Brown Discusses Work On Axonal Transport At Neuroscience Research Day, Ohio University College Of Arts & Sciences

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No abstract provided.

Illusory Motion Reveals Velocity Matching, Not Foveation, Drives Smooth Pursuit Of Large Objects, Scott N. J. Watamaniuk, Zheng Ma, Stephen J. Heinen

Psychology Faculty Publications

When small objects move in a scene, we keep them foveated with smooth pursuit eye movements. Although large objects such as people and animals are common, it is nonetheless unknown how we pursue them since they cannot be foveated. It might be that the brain calculates an object’s centroid, and then centers the eyes on it during pursuit as a foveation mechanism might. Alternatively, the brain merely matches the velocity by motion integration. We test these alternatives with an illusory motion stimulus that translates at a speed different from its retinal motion. The stimulus was a Gabor array that translated …

Book Review: Goodbye Days, Courtney Jones

The Utah English Journal

Carver Briggs is an aspiring writer attending a prestigious school of the arts for the young and gifted in Jeff Zentner’s Goodbye Days. Carver pours hours into his work and future career, but never imagines that just two sentences could change his life forever: “Where are you guys? Text me back.” These become the most influential words he ever writes, because they result in the deaths of his three best friends.

Food Studies Usda Plant Pathologist On Transgenic Plants, Nov. 9, Ohio University College Of Arts & Sciences

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No abstract provided.

Geology Colloquium | Tales Told By Dead Shells Paleobiological Approaches To Historical Ecology And Conservation, Nov. 8, Ohio University College Of Arts & Sciences

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No abstract provided.

Ecolunch | Growth In Head-Started Diamondbacked Terrapins And Their Wild Counterparts, Nov. 29, Ohio University College Of Arts & Sciences

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No abstract provided.

Plant Biology Colloquium | Regulation Of The Nlr Immune Receptor Piz-T In Rice, Nov. 17, Ohio University College Of Arts & Sciences

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No abstract provided.

Science Café | Life After Death Element Creation In Stellar Explosions, Nov. 1, Ohio University College Of Arts & Sciences

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No abstract provided.

Biological Biomedical Seminar | Genomics Of Human Resistance To Hiv, Nov. 13, Ohio University College Of Arts & Sciences

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No abstract provided.

Ecolunch | Hot And Steamy Summer Night See That Crab Do He Bite, Nov. 8, Ohio University College Of Arts & Sciences

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No abstract provided.

Chemistry Colloquium | Vibrational Spectroscopy Recent Developments To Revolutionize Forensic Science, Nov. 13, Ohio University College Of Arts & Sciences

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No abstract provided.

Herpetology Symposium A Walk In The World Of Salamander Genomics, Nov. 10, Ohio University College Of Arts & Sciences

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No abstract provided.

Math Biology Seminar | Glycolytic Hyperactivity In Dysfunctional Oscillatory Behavior Of Pancreatic Islets, Nov. 14, Ohio University College Of Arts & Sciences

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No abstract provided.

Grad Student Evaluates Method For Studying Bird Brains, Ohio University College Of Arts & Sciences

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No abstract provided.

Math Biology Seminar | The Effect Of Impurities On Stripes, Nov. 28, Ohio University College Of Arts & Sciences

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No abstract provided.

Math-Biology Seminar | Three Disguises Of 1-X = Exp(- Lambda X), Nov. 7, Ohio University College Of Arts & Sciences

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No abstract provided.

Science News Highlights Morris Research On Animal Beauty, Ohio University College Of Arts & Sciences

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No abstract provided.

Undergraduate Researcher Investigates New Potential Therapeutic For Brain Cancer, Ohio University College Of Arts & Sciences

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No abstract provided.