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Articles 29941 - 29970 of 30182
Full-Text Articles in Entire DC Network
Phase 2 Study Of Combination Spi-1620 With Docetaxel As Second-Line Advanced Biliary Tract Cancer Treatment, Richard Kim, E. Gabriela Chiorean, Manik Amin, Caio Max S. Rocha-Lima, Jitendra Gandhi, William P. Harris, Tao Song, David Portnoy
Phase 2 Study Of Combination Spi-1620 With Docetaxel As Second-Line Advanced Biliary Tract Cancer Treatment, Richard Kim, E. Gabriela Chiorean, Manik Amin, Caio Max S. Rocha-Lima, Jitendra Gandhi, William P. Harris, Tao Song, David Portnoy
Open Access Publications
No abstract provided.
Phase I Dose-Escalation Studies Of Roniciclib, A Pan-Cyclin-Dependent Kinase Inhibitor, In Advanced Malignancies, Ramaswamy Govindan, Et Al
Phase I Dose-Escalation Studies Of Roniciclib, A Pan-Cyclin-Dependent Kinase Inhibitor, In Advanced Malignancies, Ramaswamy Govindan, Et Al
Open Access Publications
No abstract provided.
A Comparison Of Per Sample Global Scaling And Per Gene Normalization Methods For Differential Expression Analysis Of Rna-Seq Data, Xiaohong Li, Guy N. Brock, Eric C. Rouchka, Nigel G. F. Cooper, Dongfeng Wu, Timothy E. O'Toole, Ryan S. Gill, Abdallah M. Eteleeb, Liz O'Brien, Sexh N. Rai
A Comparison Of Per Sample Global Scaling And Per Gene Normalization Methods For Differential Expression Analysis Of Rna-Seq Data, Xiaohong Li, Guy N. Brock, Eric C. Rouchka, Nigel G. F. Cooper, Dongfeng Wu, Timothy E. O'Toole, Ryan S. Gill, Abdallah M. Eteleeb, Liz O'Brien, Sexh N. Rai
Open Access Publications
No abstract provided.
Dacomitinib, A Pan-Inhibitor Of Erbb Receptors, Suppresses Growth And Invasive Capacity Of Chemoresistant Ovarian Carcinoma Cells, Reza Ghasemi, Et Al
Dacomitinib, A Pan-Inhibitor Of Erbb Receptors, Suppresses Growth And Invasive Capacity Of Chemoresistant Ovarian Carcinoma Cells, Reza Ghasemi, Et Al
Open Access Publications
No abstract provided.
Genome-Wide Physical Activity Interactions In Adiposity ― A Meta-Analysis Of 200,452 Adults, Mary F. Feitosa, Llilda Barata, Ingrid B. Borecki, Et Al.
Genome-Wide Physical Activity Interactions In Adiposity ― A Meta-Analysis Of 200,452 Adults, Mary F. Feitosa, Llilda Barata, Ingrid B. Borecki, Et Al.
Open Access Publications
No abstract provided.
Primary Fibroblasts From Cspα Mutation Carriers Recapitulate Hallmarks Of The Adult Onset Neuronal Ceroid Lipofuscinosis, Bruno A. Benitez, Mark S. Sands
Primary Fibroblasts From Cspα Mutation Carriers Recapitulate Hallmarks Of The Adult Onset Neuronal Ceroid Lipofuscinosis, Bruno A. Benitez, Mark S. Sands
Open Access Publications
No abstract provided.
Targeting Cellular Calcium Homeostasis To Prevent Cytokine-Mediated Beta Cell Death, Amy L. Clark, Kohsuke Kanekura, Zeno Lavagnino, Larry D. Spears, Damien Abreu, Jana Mahadevan, Takuya Yagi, Clay F. Semenkovich, David W. Piston, Fumihiko Urano
Targeting Cellular Calcium Homeostasis To Prevent Cytokine-Mediated Beta Cell Death, Amy L. Clark, Kohsuke Kanekura, Zeno Lavagnino, Larry D. Spears, Damien Abreu, Jana Mahadevan, Takuya Yagi, Clay F. Semenkovich, David W. Piston, Fumihiko Urano
Open Access Publications
No abstract provided.
Hippocampal Slice Preparation In Rats Acutely Suppresses Immunoreactivity Of Microtubule-Associated Protein (Map2) And Glycogen Levels Without Affecting Numbers Of Glia Or Levels Of The Glutamate Transporter Vglut1, Liana R. Stein, Charles F. Zorumski, Yukitoshi Izumi
Hippocampal Slice Preparation In Rats Acutely Suppresses Immunoreactivity Of Microtubule-Associated Protein (Map2) And Glycogen Levels Without Affecting Numbers Of Glia Or Levels Of The Glutamate Transporter Vglut1, Liana R. Stein, Charles F. Zorumski, Yukitoshi Izumi
Open Access Publications
No abstract provided.
Yin And Yang Of Interleukin-17 In Host Immunity To Infection [Version 1; Referees: 2 Approved], Shibali Das, Shabaana Khader
Yin And Yang Of Interleukin-17 In Host Immunity To Infection [Version 1; Referees: 2 Approved], Shibali Das, Shabaana Khader
Open Access Publications
No abstract provided.
Leisure-Time Physical Activity And Circulating 25-Hydroxyvitamin D Levels In Cancer Survivors: A Cross-Sectional Analysis Using Data From The Us National Health And Nutrition Examination Survey, Lin Yang, Adetunji T. Toriola
Leisure-Time Physical Activity And Circulating 25-Hydroxyvitamin D Levels In Cancer Survivors: A Cross-Sectional Analysis Using Data From The Us National Health And Nutrition Examination Survey, Lin Yang, Adetunji T. Toriola
Open Access Publications
No abstract provided.
Interferon-Lambda: A Potent Regulator Of Intestinal Viral Infections, Sanghyun Lee, Megan T. Baldridge
Interferon-Lambda: A Potent Regulator Of Intestinal Viral Infections, Sanghyun Lee, Megan T. Baldridge
Open Access Publications
No abstract provided.
Prevalence And Predictors Of Postdischarge Antibiotic Use Following Mastectomy, Margaret A. Olsen, Katelin B. Nickel, Victoria J. Fraser, Anna E. Wallace, David K. Warren
Prevalence And Predictors Of Postdischarge Antibiotic Use Following Mastectomy, Margaret A. Olsen, Katelin B. Nickel, Victoria J. Fraser, Anna E. Wallace, David K. Warren
Open Access Publications
No abstract provided.
The Power Of The Few, Ran Chen, Yuan Pan, David H. Gutmann
The Power Of The Few, Ran Chen, Yuan Pan, David H. Gutmann
Open Access Publications
No abstract provided.
Interfacing Peripheral Nerve With Macro-Sieve Electrodes Following Spinal Cord Injury, Nathan K. Birenbaum, Matthew R. Macewan, Wilson Z. Ray
Interfacing Peripheral Nerve With Macro-Sieve Electrodes Following Spinal Cord Injury, Nathan K. Birenbaum, Matthew R. Macewan, Wilson Z. Ray
Open Access Publications
No abstract provided.
The Mycobacterium Tuberculosis Mmpl11 Cell Wall Lipid Transporter Is Important For Biofilm Formation, Intracellular Growth, And Nonreplicating Persistence, Catherine C. Wright, Fong Fu Hsu, Eusondia Arnett, Jennifer L. Dunaj, Patrick M. Davidson, Sophia A. Pacheco, Melanie J. Harriff, David M. Lewinsohn, Larry S. Schlesinger, Georgiana E. Purdy
The Mycobacterium Tuberculosis Mmpl11 Cell Wall Lipid Transporter Is Important For Biofilm Formation, Intracellular Growth, And Nonreplicating Persistence, Catherine C. Wright, Fong Fu Hsu, Eusondia Arnett, Jennifer L. Dunaj, Patrick M. Davidson, Sophia A. Pacheco, Melanie J. Harriff, David M. Lewinsohn, Larry S. Schlesinger, Georgiana E. Purdy
Open Access Publications
No abstract provided.
Targeting The Differential Addiction To Anti-Apoptotic Bcl-2 Family For Cancer Therapy, Akane Inoue-Yamauchi, Paul S. Jeng, Kwanghee Kim, Hui-Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria C. Pietanza, Matthew D. Hellmann, Mark G. Kris, James J. Hsieh, Emily H. Cheng
Targeting The Differential Addiction To Anti-Apoptotic Bcl-2 Family For Cancer Therapy, Akane Inoue-Yamauchi, Paul S. Jeng, Kwanghee Kim, Hui-Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria C. Pietanza, Matthew D. Hellmann, Mark G. Kris, James J. Hsieh, Emily H. Cheng
Open Access Publications
No abstract provided.
Ectopy On A Single 12‐Lead Ecg, Incident Cardiac Myopathy, And Death In The Community, Kaylin T. Nguyen, Eric Vittinghoff, Thomas A. Dewland, Jonathan W. Dukes, Elsayed Z. Soliman, Phyllis K. Stein, John S. Gottdiener, Alvaro Alonso, Lin Y. Chen, Bruce M. Psaty, Susan R. Heckbert, Gregory M. Marcus
Ectopy On A Single 12‐Lead Ecg, Incident Cardiac Myopathy, And Death In The Community, Kaylin T. Nguyen, Eric Vittinghoff, Thomas A. Dewland, Jonathan W. Dukes, Elsayed Z. Soliman, Phyllis K. Stein, John S. Gottdiener, Alvaro Alonso, Lin Y. Chen, Bruce M. Psaty, Susan R. Heckbert, Gregory M. Marcus
Open Access Publications
No abstract provided.
How Much Has The Supreme Court Changed Patent Law?, Paul Gugliuzza
How Much Has The Supreme Court Changed Patent Law?, Paul Gugliuzza
Faculty Scholarship
The U.S. Supreme Court has decided a remarkable number of patent cases in the past decade, particularly as compared to the first twenty years of the Federal Circuit’s existence. No longer is the Federal Circuit “the de facto Supreme Court of patents,” as Mark Janis wrote in 2001. Rather, it seems the Supreme Court is the Supreme Court of patents. In the article at the center of this symposium, Judge Timothy Dyk of the Federal Circuit writes that the Supreme Court’s decisions “have had a major impact on patent law,” citing, among other evidence, the Court’s seventy percent reversal rate …
All Things Loved And Unlovable: Discovering Southern Identity In Black Migration Novels, Michael Holman
All Things Loved And Unlovable: Discovering Southern Identity In Black Migration Novels, Michael Holman
Honors Theses
This thesis traces the development of the ways that the South figures in the imaginations of black writers by examining Southern identity in three novels centered around migratory protagonists. The thesis examines the ways in which folk identity, urban landscapes, remigration, and gender shape the migration experience in each novel. The novels discussed here are Nella Larsen's Quicksand, Ralph Ellison's Invisible Man, and Toni Morrison's Song of Solomon. Quicksand posits the South as a place of unique danger, especially for black women, Invisible Man characterizes it as a place defined by oppressive memory that may be utilized as a resource …
There's Only This: Atheism And The Search For Meaning In Ian Mcewan's Fiction, Olivia Hope Davis
There's Only This: Atheism And The Search For Meaning In Ian Mcewan's Fiction, Olivia Hope Davis
Honors Theses
In this thesis, I offer readings of Ian McEwan's Enduring Love, Saturday, and The Children Act to study the relationship between meaning and faith. This is an important question because some New Atheists have pointed to McEwan's work as proof that meaning is possible in the absence of God. In this thesis I suggest that while McEwan makes a strong case for the possibility of meaning through aesthetic experiences, he also complicates meaning by suggesting that it is only achievable in the context of belief in the irreducibility of ideas like love, beauty, and wonder.
Photophysical Characterization Of Newly-Synthesized Emissive Materials, Rachael Abigayle Nelson
Photophysical Characterization Of Newly-Synthesized Emissive Materials, Rachael Abigayle Nelson
Honors Theses
One key element in chemistry is understanding the chemical properties of a molecule so that its interactions with itself, other atoms or molecules, or its environment is well known. This knowledge alone allows the chemist to innovate and invent and thereby change the world. Light surrounds and sustains our lives; thus it is vital to understand how light interacts with common and newly synthesized materials. In this thesis the photophysical properties of newly synthesized materials will be discussed to give an overview of the many ways in which light interacts with the chemical materials composing our everyday lives. General photophysical …
Cross-Cultural Comparison Of Cosmetic Procedures In Latin America And East Asia, Rebecca Vorisek
Cross-Cultural Comparison Of Cosmetic Procedures In Latin America And East Asia, Rebecca Vorisek
Honors Theses
This paper explores the factors that influence women's decisions to undergo cosmetic procedures, including: globalization, westernization, patriarchy, empowerment, and endogenous factors. It specifically focuses on East Asia and Latin America focusing on South Korea, China, Brazil, and Argentina and offers a cross-cultural comparison between these regions and countries as well as between the world and the West. I compiled and analyzed data from the International Society of Aesthetic Plastic Surgery (ISAPS) 2011 annual report to create profiles of the most common cosmetic procedures performed for each region and country, and these profiles were then compared to one another. Through my …
An Analysis Of The Financial Literacy Of Senior Students Across Fields Of Study At The University Of Mississippi, Robert Hollis Burrow
An Analysis Of The Financial Literacy Of Senior Students Across Fields Of Study At The University Of Mississippi, Robert Hollis Burrow
Honors Theses
This thesis examines the financial literacy of senior students at the University of Mississippi, as well as which variables influence a student's financial literacy level. Financial literacy is crucial for both an individual's current and long-term well-being and financial health. Students in various major fields of study participated in a multiple-choice survey, including demographic, socioeconomic, and financial literacy questions. The student's answers were analyzed using univariate analyses, an ordinary least squares stepwise regression, and a logistic stepwise regression. The study found that the average student score of 2.75 out of five financial literacy questions was comparable to the national average …
Platelet-Derived Microparticles And Their Role In Sepsis, Robert Tramel
Platelet-Derived Microparticles And Their Role In Sepsis, Robert Tramel
Honors Theses
Causing at least 215,000 deaths in the U.S. annually- more than prostate cancer, breast cancer, and AIDS combined- and rising, sepsis is one of the most deadly medical conditions in America. Sepsis pathophysiology, however, is still incompletely understood, making it difficult for physicians to diagnosis and treat effectively. Given the time-sensitivity of treatment, researchers are now searching for new methods to identify sepsis early, developing more accurate prognostic markers, and developing new target therapeutic candidates. One biological component of interest in this research is the platelet-derived microparticle (PMP), a heterogeneous vesicle derived from the cell membrane of platelets found circulating …
An Integrative Synthetic, Spectroscopic, And Computational Study Of The Free Radical Chlorine Dioxide And Its Interactions With Hydrogen Bonded Networks, Sarah C. Sutton
An Integrative Synthetic, Spectroscopic, And Computational Study Of The Free Radical Chlorine Dioxide And Its Interactions With Hydrogen Bonded Networks, Sarah C. Sutton
Honors Theses
The free radical chlorine dioxide (ClO2) is a strong oxidizing agent that is used to purify drinking water and medical equipment. The existing literature shows discrepancies in the explanation of the solvent dependent properties of ClO2. The following thesis investigates these properties by integrating integrates inorganic synthesis, spectroscopic analyses, and computational methods. ClO2/water hydrogen-bonded networks were computed with the DFT method B3LYP with 6-31G(d,p) and 6-311++G(2df, 2pd) basis sets. Raman frequency computations were performed on local minima geometries. Experimental Raman spectra of chlorine dioxide solvated in water and methanol were obtained, and the fundamental symmetric stretch (nu1) of each spectrum …
Psammaplins Selectively Target Triple-Negative Metastatic Breast Tumor Cells That Are Genetically Programmed To Colonize Specific Organs, Thuy Phuong Le
Psammaplins Selectively Target Triple-Negative Metastatic Breast Tumor Cells That Are Genetically Programmed To Colonize Specific Organs, Thuy Phuong Le
Honors Theses
Five bromotyrosine-derived marine sponge metabolites, four psammaplins (1 — 4) and the psammaplin dimer, bisaprasin (5) were isolated from a lipid extract sample of the marine sponge Dendrilla lacunosa. Â Psammaplins act as histone deacetylase (HDAC) inhibitors that alter cellular gene expression. Â The D. lacunosa psammaplins activated the oxygen regulated transcription factor HIF-1 (hypoxia-inducible factor-1) in T47D human breast tumor cells and displayed cell line specific effects against aggressive organotropic metastatic cell lines that were derived from triple-negative MDA-MB-231 human breast tumor cells.
Spectroscopic And Computational Studies Of The Hydrogen Bonding Interactions Of Hydroxyethyl Ethers, Ashley Elizabeth Williams
Spectroscopic And Computational Studies Of The Hydrogen Bonding Interactions Of Hydroxyethyl Ethers, Ashley Elizabeth Williams
Honors Theses
The isoenzymatic form of microsomal cytochrome P450, CYP2E1, is involved in the formation of oxygen free radicals, specifically hydroxyethyl ether. Chronic alcohol abuse has been found to induce larger levels of CYP2E1 in the liver, thus increasing production of these harmful free radicals. Generation of the hydroxyethyl ether oxygen free radicals occurs during the metabolism of ethanol in microsomes. The hydrogen-bonding interactions of hydroxyethyl ethers with water have yet to be analyzed, and information regarding the interactions with water can be applied directly to biological systems. Here, we employ Raman spectroscopy and computational chemistry to study hydroxyethyl ether complexes in …
Randomized Phase 2 Trial Of Regadenoson For Treatment Of Acute Vaso-Occlusive Crises In Sickle Cell Disease, Joshua J. Field, Elaine Majerus, Victor R. Gordeuk, Michel Gowhari, Carolyn Hoppe, Matthew M. Heeney, Maureen Achebe, Alex George, Hillary Chu, Brian Sheehan, Maneka Puligandla, Donna Neuberg, Gene Lin, Joel Linden, David G. Nathan
Randomized Phase 2 Trial Of Regadenoson For Treatment Of Acute Vaso-Occlusive Crises In Sickle Cell Disease, Joshua J. Field, Elaine Majerus, Victor R. Gordeuk, Michel Gowhari, Carolyn Hoppe, Matthew M. Heeney, Maureen Achebe, Alex George, Hillary Chu, Brian Sheehan, Maneka Puligandla, Donna Neuberg, Gene Lin, Joel Linden, David G. Nathan
Open Access Publications
No abstract provided.
Narrowing The Spectrum: The New Frontier Of Precision Antimicrobials, Alexandra E. Paharik, Henry L. Schreiber Iv, Caitlyn N. Spaulding, Karen W. Dodson, Scott J. Hultgren
Narrowing The Spectrum: The New Frontier Of Precision Antimicrobials, Alexandra E. Paharik, Henry L. Schreiber Iv, Caitlyn N. Spaulding, Karen W. Dodson, Scott J. Hultgren
Open Access Publications
No abstract provided.
Structured Illumination Diffuse Optical Tomography For Noninvasive Functional Neuroimaging In Mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, Joseph P. Culver
Structured Illumination Diffuse Optical Tomography For Noninvasive Functional Neuroimaging In Mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, Joseph P. Culver
Open Access Publications
No abstract provided.