Digital Commons Network^™

Identification Of Nitric-Oxide Degradation Products Of Ascorbic Acid, Sushant Satyanarayan Kolipaka

Dissertations, Master's Theses and Master's Reports

Nitric oxide (NO) has been shown to possess many Anti-inflammatory effects. Ascorbic acid which is naturally present in human body is known to react with S-nitrosothiols (RSNO) directly to reduce RSNO to NO and produce free thiol groups, if present in more than millimolar concentration. Higher concentration of ascorbic acid is required because the reduction of RSNO is not caused by ascorbate instead, but instead a decomposed product of ascorbic acid. S-Nitroso-N-Acetylpenicillamine is used as an NO donor. An HPLC method is used for determination of the degradation product of ascorbic acid and simultaneously identifying the compound responsible for NO …

The Spatial Ecology Of Gray Wolves In The Upper Peninsula Of Michigan, 1994–2013, Shawn O'Neil

Dissertations, Master's Theses and Master's Reports

All natural processes are dynamic in space and time. Establishing the links between spatiotemporal patterns and ecological processes is critical for improving our understanding of natural systems. Empirical data representing wildlife populations is accumulating and increasingly involves spatiotemporal components. Wildlife monitoring programs for threatened, endangered, or other species of interest often involve radio-tracking of a sample of individual animals combined with census data. Such data are valuable both for conservation and management of populations and for testing ecological theories about species distribution and what influences patterns over time. We used 20 years of radio telemetry and snow tracking data to …

Rock Magnetic Investigation Of The Michigan Basin Soils And Sediments Overlying The Oil-Bearing Silurian Pinnacle Reefs, Jake Tresnak

Dissertations, Master's Theses and Master's Reports

A relationship between the hydrocarbon migration and magnetic properties of near-surface sediments was investigated from several hundreds of samples collected over the hydrocarbon-bearing Silurian pinnacle reef belt of the Michigan Basin. The collected samples were investigated using several rock magnetic methods and optical microscopy. The investigation has not revealed a straightforward relationship between the magnetic susceptibility and hydrocarbon reservoirs within the reef belt; both anomalously high and low susceptibility values were observed. The elevated values are associated with newly formed magnetite in the form of spheroidal grains produced by hydrocarbon-related diagenesis while the extremely low susceptibilities may reflect dissolution of …

The Visual And Performing Arts In The Technical Communication Classroom: Reinforcing The University's Internal Community Literacy Via Service-Learning, Richard L. Ward

Dissertations, Master's Theses and Master's Reports

This report details a class taught that was an exploration into the value of STEAM or science, technology, engineering, arts, and mathematics within the confines of Technical Communication as it applies to the business and industry of theatre. It was an experiment in service learning as it could be tied into the Arts via differing technai, as described by John Wild in “Plato’s Theory of Texnh a Phenomenological Interpretation,” demonstrating a necessity for Arts as they pertain to STEM-centric universities. This report discusses a section of Technical and Professional Communication taught at Michigan technological University that consisted of twenty-five students …

Dynamics Of Wild Red Raspberry (Rubus Idaeus L.) And The Influence On Tree Regeneration Within Silvicultural Openings In A Northern Hardwood Stand, Matthew J. Widen

Dissertations, Master's Theses and Master's Reports

Previous studies have investigated how the abundance of raspberries (Rubus idaeus L.) impacts tree regeneration, but few have linked these impacts to location within canopy openings with a legacy tree. To fill this knowledge gap, we investigated the presence, abundance, and location of raspberries within openings containing legacy trees and the resulting impacts on tree regeneration. During the winter of 2003, 49 openings were created of three sizes: small, medium, large and 20 reference single-tree selection sites in a northern hardwood stand in Ford Forest near Alberta, Michigan. Tree regeneration and vegetative species cover were recorded in 2005 and …

Laboratory, Computational And Theoretical Investigations Of Ice Nucleation And Its Implications For Mixed Phase Clouds, Fan Yang

Dissertations, Master's Theses and Master's Reports

Ice particles in atmospheric clouds play an important role in determining cloud lifetime, precipitation and radiation. It is therefore important to understand the whole life cycle of ice particles in the atmosphere, e.g., where they come from (nucleation), how they evolve (growth), and where they go (precipitation). Ice nucleation is the crucial step for ice formation, and in this study, we will mainly focus on ice nucleation in the lab and its effect on mixed-phase stratiform clouds.

In the first half of this study, we investigate the relevance of moving contact lines (i.e., the region where three or more phases …

On The Logic, Method And Scientific Diversity Of Technical Systems: An Inquiry Into The Diagnostic Measurement Of Human Skin, Joel Beatty

Dissertations, Master's Theses and Master's Reports

This dissertation explores some of the scientific, technical and cultural history of human skin measurement and diagnostics. Through a significant collection of primary texts and case studies, I track the changing technologies and methods used to measure skin, as well as the scientific and sociotechnical applications. I then map these histories onto some of the diverse understandings of the human body, physics, biology, natural philosophy and language that underpinned the scientific enterprise of skin measurement. The main argument of my thesis demonstrates how these diverse histories of science historically and theoretically inform the succeeding methods and applications for skin measurement …

Methane Fluxes And Porewater Dissolved Organic Carbon Dynamics From Different Peatlands Types In The Pastaza-Marañon Basin Of The Peruvian Amazon., Jhon Del Aguila-Pasquel

Dissertations, Master's Theses and Master's Reports

Relevant components of the carbon budget such as methane fluxes and porewater dissolved organic carbon (DOC) are poorly characterized in the Peruvian Pastaza Marañon basin (PMB). PMB is associated with a tropospheric hotspot for methane and therefore it may represent a significant methane source. We aimed to quantify the magnitude of CH₄ fluxes and porewater DOC; and to determine their predictors across different peatland types in the PMB (open peatland, palm swamp, and pole forest). The study was conducted in two peatland sites covering the three main vegetation types in PMB. We collected gas and water samples using chamber-based …

Catalytic Hydrotreatment For The Development Of Renewable Transportation Fuels, Lilu Funkenbusch

Dissertations, Master's Theses and Master's Reports

Biologically-derived feedstocks are a highly desirable source of renewable transportation fuel. They can be grown renewably and can produce fuels similar in composition to conventional fossil fuels. They are also versatile and wide-ranging. Plant oils can produce renewable diesel and wood-based pyrolysis oils can be made into renewable gasoline. Catalytic hydrotreatment can be used to reduce the oxygen content of the oils and increase their viability as a “drop-in” transportation fuel, since they can then easily be blended with existing petroleum-based fuels. However, product distribution depends strongly on feedstock composition and processing parameters, especially temperature and type of catalyst. Current …

Anti-Inflammatory And Immune-Modulating Effects Of Rice Callus Suspension Culture And Blueberry Extract On An In-Vitro Inflammatory Bowel Disease Model, Kyle Michael Driscoll

Dissertations, Master's Theses and Master's Reports

Rice Callus Suspension Culture (RCSC) has been shown to exhibit potent anticancer activity in vitro. In this study we aimed to investigate the anti-inflammatory and immune-modulating properties of RCSC on three inflamed normal colon epithelial cell lines, InEpC, NCM 356, and CCD 841 CoN. As a comparative, we additionally analyzed the anti-inflammatory effects of Highbush blueberries on two inflamed colon cell cultures, NCM 356 and CCD 841 CoN. Furthermore, we sought to characterize the bioactive compounds in RCSC responsible for anti-cancer, anti-inflammatory, and immune-modulating effects. This work will be an essential starting point for understanding and identifying possible bioactive …

Electrospinning Novel Aligned Polymer Fiber Structures For Use In Neural Tissue Engineering, Rachel Martin

Dissertations, Master's Theses and Master's Reports

A suitable tissue scaffold to support and assist in the repair of damaged tissues or cells is important for success in clinical trials and for injury recovery. Electrospinning can create a variety of polymer nanofibers and microfibers, and is being widely used to produce experimental tissue scaffolds for neural applications. This dissertation examines various approaches by which electrospinning is being used for neural tissue engineering applications for the repair of injuries to the central nervous system (CNS) and the peripheral nervous system (PNS). Due to the poor regeneration of neural tissues in the event of injury, tissue scaffolds are being …

Impacts To Biodiversity And Ecosystem Services From Bioenergy Development: A Pan American Experience, Colin Phifer

Dissertations, Master's Theses and Master's Reports

As part of a broader project that evaluated the social and ecological sustainability of bioenergy, I studied the effects of bioenergy associated land-use change and management on native bees and birds in two bioenergy-producing countries, the United States and Argentina. In Argentina, I worked in Entre Ríos province where eucalyptus (Eucalyptus spp.) plantations are being planted. These fast-growing trees are replacing pasture and annual crops, the current dominant land use. I surveyed for native bees and birds in pastures/annual crops and large-scale eucalyptus plantations, as well as mixed-use farms and native espinal savannas. Both birds and bees declined in …

Evaluation Of Biochar As A Feed Additive In Commercial Broiler Diets, Brandon Michael Cheron

LSU Master's Theses

Two experiments were conducted to evaluate sugarcane biochar as a feed ingredient in commercial broiler diets. Experiment 1 was conducted for 11 days using 300 male Ross 708 broilers. Broilers were allotted to one of five treatment diets containing 0%, 0.5%, 1.0%, 2%, or 4% biochar. Experiment 2 was conducted for 19 days using 450 male Ross 708 broilers. Chicks were allotted to one of 9 treatment diets containing 0%, 0.25%, 0.5%, 0.75%, 1%, 1.25%, 1.5%, 1.75% or 2% biochar. Broilers and feed were weighed at day 0 and 10 in experiment 1 and day 0, 10 and 18 in …

Dynamic Modelling Of Local Government Wealth When Shocked By Natural Disasters, Alejandra Brevé Ferrari

LSU Master's Theses

Hurricane Katrina struck the Gulf Coast as a Category 3 storm on August 29th of 2005. It is the costliest natural disaster in U.S. history. Communities across the country are increasingly at risk of being affected by natural and environmental disasters. The Public Assistance Grant Program (PA Program) administered by the Federal Emergency Management Agency (FEMA) is available for states and communities that have received a major or emergency disaster declaration. Most of Emergency Management (EM) research has focused on preparedness and mitigation activities; considerably less research has studied post disaster response. Two of the initial and most important aspects …

Characterization Of Genic Microsatellite Markers (Est-Ssrs) In The Endangered Oak Species Quercus Georgiana M.A.Curtis, Priyanka Dipak Kadav

Dissertations, Master's Theses and Master's Reports

Quercus is important ecologically and economically because it provides food and habitat for wildlife, wood and paper products for humans. Oaks are endangered due to various factors like shifting climates, habitat loss, drought, pathogens and genetic swamping. Quercus georgiana (M.A. Curtis) is an endangered and restricted oak species which is remaining only in the southeastern part of the US. Efforts are required to conserve this endangered species from extinction. Conservation of this species can be done through these methods: ex-situ conservation (arboretum and botanical garden) and in-situ conservation strategies which protect the species in its natural habitat. For this conservation …

Modeling And Simulation Of The Peristaltic Flow Of Newtonian And Non-Newtonian Fluids With Application To The Human Body, Samer Alokaily

Dissertations, Master's Theses and Master's Reports

Computational models are developed to investigate peristaltic motion in the human gastro-intestinal tract. The peristaltic motion is simulated by means of traveling waves which deform the boundary of the tubes. An axisymmetric tube of uniform diameter is used to model the small intestines, and an axisymmetric conical geometry is developed to model the lower part of the human stomach. The conical geometry represents a simplification of the more complicated three-dimensional models of the human stomach that have been used in other studies. Also, they seeks to reduce computational costs and circumvent difficulties of mesh generation. The computations are performed within …

Assessing Growth, Yield, And Carbon Dynamics In Upper Great Lakes Jack Pine And Hybrid Poplar Managed For Biomass Production, Ashlee Baker Lehner

Dissertations, Master's Theses and Master's Reports

Woody biomass for use as coal-replacing bioenergy has garnered increasing interest as federal and local governments require larger portions of energy production to come from renewable sources. Woody biomass can be produced from dedicated plantations grown and harvested solely for biomass production, or non-dedicated sources such as harvest residues from traditional timber operations. The creation of site index curves for hybrid poplar were established from the Michigan Technological University Hybrid Poplar Network in the upper Great Lakes Region. These site index models are to be used for landowners to assess the predicted yield at established plantations, or possibly within spatial …

Effects Of Wildfire Severity On Early Successional Dynamics In Boreal Peatland Complexes, Elizabeth Ernst

Dissertations, Master's Theses and Master's Reports

The Arctic-boreal region is experiencing changes in climate, trending toward warmer summers, resulting in a greater occurrence of wildfires with longer burning periods and higher intensities. Drought-like conditions dry surface fuels, leading to a higher probability of ignition, even in lowland peatlands. Previous work has been done to characterize post-fire succession rates in boreal upland sites, but much less is known of fire effects and early successional dynamics in lowland peatlands. Areas surrounding the Great Slave Lake in Canada’s Northwest Territories experienced exceptional wildfire activity in 2014 and 2015. These fires burned a variety of ecotypes, including bogs, fens, other …

Fluorescent Probe Development For Fructose Specific Transporters In Cancer, Joseph Fedie

Dissertations, Master's Theses and Master's Reports

Carbohydrate transporters or GLUTs of the major facilitator superfamily (MFS) are responsible for transporting sugars into the cell and have been of research interest for decades. Disruptions, mutations, and over-activations of GLUTs have been linked to a number of major diseases including cancer, obesity, and diabetes. Differentiating between transporters is incredibly difficult due to highly conserved structures, and so specific targeting between transporters has proven a complex challenge. GLUTs are highly flexible in their conformations however exactly what will and will not pass through the transporter is ambiguous at best, and many attempt to target these transporters have failed.

In …

Traditional Medicine Use In Chamorro Cué, Gral. E. Aquino, San Pedro, Paraguay, Noah Goyke

Dissertations, Master's Theses and Master's Reports

Rural Paraguay presents great opportunities for investigation into the subtle differences in the use of medicinal plants across seasons and the urban versus rural dichotomy in a rapidly globalizing society. One of the most interesting opportunities is comparing a rural population to the population of an urban center that has be the destination of local migration from the rural communities surveyed. This study investigates the seasonal differences and difference between urban and rural residents in the type of medication used to treat thirteen different common ailments and the source of medicinal plants used to treat those ailments. Interviews performed in …

A Wireless, Passive Sensor For Measuring Temperature At Orthopedic Implant Sites For Early Diagnosis Of Infections, Salil Sidharthan Karipott

Dissertations, Master's Theses and Master's Reports

Sensorized implants with embedded wireless, passive temperature sensors were developed for early detection of implant-associated infections. The operation principle of the sensor is based on the hypothesis that infections can lead to an increase in local temperature prior to the rise of body temperature. The sensor was an inductive capacitive (LC) circuit that has been used for monitoring of different parameters wirelessly, often in difficult to access environments. The sensor was fabricated on to an interference screw, which is used for tendon and ligament reconstruction surgeries. In this project, a sensorized interference screw was designed and fabricated by accommodating an …

Using Lidar To Map The Geology And Morphology Of Alluvial Fans: Salton Sea Area, California, Eric Alexander Macleod

Dissertations, Master's Theses and Master's Reports

The main result of this study has been to show that detailed maps of the geology and morphology of alluvial fans can be generated from high spatial resolution (1-meter) DEM’s (Digital Elevation Models) obtained from LiDAR (Light Detection and Ranging) data. DEMs with spatial resolutions of 1-meter, 10-meters and 30-meters were all examined but it was determined that only the 1-meter LiDAR data had sufficient spatial resolution to produce satisfactory maps of the geology and morphology. A case study on an alluvial fan in the Santa Rosa mountains northeast of the Salton Sea (California) showed that 1-meter spatial resolution LiDAR …

A 3d Biomimetic Scaffold Using Electrospinning For Tissue Engineering Applications, Samerender Nagam Hanumantharao

Dissertations, Master's Theses and Master's Reports

Electrospinning holds great promise for designing functional 3D biomimetic scaffolds for tissue engineering applications. The technique allows for the reproducible fabrication of 3D scaffolds with control over the porosity and thickness. In this work, a novel method for the synthesis of a 3D electroactive scaffold using electrospinning from polycaprolactone (PCL), Polyvinylidene Fluoride (PVDF) and Polyaniline (PANI) is reported. Additional scaffolds involving different morphologies of PCL, PCL-PVDF and PCL-PANI-PVDF were also fabricated and evaluated. The scaffolds were characterized using electron microscopy to visualize the morphologies. Infrared spectroscopy was used to confirm the presence of polymers and their respective phases in the …

Students’ Understanding Of Finger Lakes Geology Using A Field Study, Jonathan D. Pragle

Dissertations, Master's Theses and Master's Reports

The Finger Lakes area has some of the most unique geologic features in New York State including much evidence of the impact that glaciers have had on this environment. The area is rich in Devonian and Silurian era fossils, drumlins, U-shaped valleys, and glacial erratics. With all of this evidence it is easy to imagine a class of students outside in the environment examining these structures and developing conclusions about their origin. However, students in the Finger Lakes area are generally taught about the geology of the area using traditional techniques utilizing technology and diagrams in the classroom. In this …

Structural Characteristics And Corrosion Behavior Of Bio-Degradable Zn-Li Alloys In Stent Application, Shan Zhao

Dissertations, Master's Theses and Master's Reports

Zinc has begun to be studied as a bio-degradable material in recent years due to its excellent corrosion rate and optimal biocompatibility. Unfortunately, pure Zn’s intrinsic ultimate tensile strength (UTS; below 120 MPa) is lower than the benchmark (about 300 MPa) for cardiovascular stent materials, raising concerns about sufficient strength to support the blood vessel. Thus, modifying pure Zn to improve its mechanical properties is an important research topic.

In this dissertation project, a new Zn-Li alloy has been developed to retain the outstanding corrosion behavior from Zn while improving the mechanical characteristics and uniform biodegradation once it is implanted …

Development And Characterization Of Histidine-Tagged Hpv16 L2 And Ms2-Arginine-Tagged Recombinant Proteins For Downstream Processes, Tahiyat Alothaim

Dissertations, Master's Theses and Master's Reports

Human papillomaviruses (HPVs) are the most common sexually transmitted infections. Persistent infection with HPV can lead to anogenital cancers including head and neck cancers. Three prophylactic vaccines have been approved to prevent against some types of HPV infection. However, the vaccines are HPV-type specific and protect mostly against the HPV types included in the vaccines. To offer broader protection against more HPV types, studies in the field are developing candidate vaccines targeting a conserved minor capsid protein, L2. Nevertheless, reagents for developing and assessing L2 vaccines are limited. For example, antibodies to assess the antigenicity of some L2 epitopes are …

Characterization Of Ecological Water Stress In The U.S. Great Lakes Region Using A Geospatial Modeling Approach, Sara Alian

Dissertations, Master's Theses and Master's Reports

Anthropocentric water resources management affects aquatic habitats by changing streamflow regime. Understanding the impacts of water withdrawal from different sources and consumption by various economic sectors at different spatial and temporal scales is key to characterizing ecologically harmful streamflow disturbances. To this end, we developed a generic, integrative framework to characterize catchment scale water stress at annual and monthly time scales. The framework accounts for spatially cumulative consumptive and non-consumptive use impacts and associated changes in flow due to depletion and return flow along the stream network. Application of the framework to the U.S. Great Lakes Region indicates that a …

Effects Of In-Situ Leaf-Level Canopy Warming In A Northern Hardwood Forest, Kelsey Carter

Dissertations, Master's Theses and Master's Reports

Rising mean annual temperatures due to climate change have intensified the need to understand the effects of warming on plant physiological processes. Forest photosynthesis is the most important pathways of terrestrial carbon sequestration, yet continued warming could reduce this important carbon sink. Photosynthesis is highly sensitive to temperature and begins to decline after an optimum temperature (T_opt) is reached, leading to reduced carbon uptake. To date, logistical difficulties have limited our ability to test photosynthetic responses to sustained warming in mature forest canopies. In order to understand how elevated temperatures will affect forest ecosystems, we need to be …

Effects Of The Biological Reagent Iptg On Expression Of The Protein Afudg, Joseph Miller, Samuel Hendrickx

Celebrating Scholarship & Creativity Day (2011-2017)

No abstract provided.

Parent-Child Interaction : How It Impacts Language And Literacy Skills, Angie Thurman

Graduate Research Papers

The purpose of this review is to examine the importance of parent-child interaction in children ages birth through five-years old. The review focuses on how these interactions impact literacy and language skills in young children. Parent interventions and strategies to help children grow in the areas of literacy and language are also highlighted. The conclusion of this review includes recommendations for parents and teachers as well as suggestions for future research.