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2017

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The Comparison Of Antioxidant Capacity And Cytotoxic, Anticarcinogenic,And Genotoxic Effects Of Fe@Au Nanosphere Magnetic Nanoparticles, Hande Yegenoglu, Belma Aslim, Burcu Guven, Adem Zengin, İsmai̇l Hakki Boyaci, Zeki̇ye Suludere, Uğur Tamer Jan 2017

The Comparison Of Antioxidant Capacity And Cytotoxic, Anticarcinogenic,And Genotoxic Effects Of Fe@Au Nanosphere Magnetic Nanoparticles, Hande Yegenoglu, Belma Aslim, Burcu Guven, Adem Zengin, İsmai̇l Hakki Boyaci, Zeki̇ye Suludere, Uğur Tamer

Turkish Journal of Biology

Magnetic gold nanoparticles are used in various biomedical, biochemistry, and biotechnology applications due to their controllable size distribution, long-term stability, reduced toxicity, and biocompatibility. Different coating materials, such as proteins, carbohydrates, lipids, and polyphenols, are applied to enhance the biocompatibility of nanoparticles. In this study, the effects of surface coatings of core-shell structured Fe@Au nanosphere magnetic nanoparticles with regard to antioxidant capacity and cytotoxic, anticarcinogenic, and genotoxic properties were investigated. The obtained results demonstrated that avidin-coated Fe@Au nanospheres had higher antioxidant capacities than uncoated nanospheres. Neither avidin-coated nor uncoated nanoparticles had a cytotoxic effect on normal cells (human gingival fibroblast …

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Amperometric Biosensor For Detection Of Triglyceride Tributyrinbased On Zero Point Charge Of Activated Carbon, Mohsen Rezvani, Ghasem Najafpour, Maedeh Mohammadi, Hossein Zare Jan 2017

Amperometric Biosensor For Detection Of Triglyceride Tributyrinbased On Zero Point Charge Of Activated Carbon, Mohsen Rezvani, Ghasem Najafpour, Maedeh Mohammadi, Hossein Zare

Turkish Journal of Biology

A simple and robust single enzyme biosensor was fabricated for triglyceride (TG) detection. Graphite rods were modified with activated carbon (AC) and used as support for lipase immobilization. Chitosan (CHIT) was eventually used to create film on the bioelectrode and retain the immobilized enzyme. To extend the linear range of TG detection, AC was functionalized with carboxyl and then amine groups (AAC) to enhance the isoelectric point of AC. The constructed graphite/AAC/lipase /CHIT bioelectrode was characterized using cyclic voltammetry and field emission scanning electron microscopy (FE-SEM). The accuracy of the developed biosensor was assessed through determination of different concentrations of …

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Exogenously Sourced γ-Irradiated Chitosan-Mediated Regulation Of Growth, Physiology, Quality Attributes And Yield In Mentha Piperita L., Bilal Ahmad, Mohammad Masroor Akhtar Khan, Hassan Jaleel, Yawar Sadiq, Asfia Shabbir, Moin Uddin Jan 2017

Exogenously Sourced γ-Irradiated Chitosan-Mediated Regulation Of Growth, Physiology, Quality Attributes And Yield In Mentha Piperita L., Bilal Ahmad, Mohammad Masroor Akhtar Khan, Hassan Jaleel, Yawar Sadiq, Asfia Shabbir, Moin Uddin

Turkish Journal of Biology

In view of the increasing demand for essential oils from medicinal and aromatic plants, the application of irradiated polysaccharides like chitosan is a promising option. A pot experiment was performed to study the influence of various concentrations of irradiated chitosan (ICN) on growth, physiological, and yield parameters of Mentha piperita L., a plant with considerable pharmaceutical importance. The treatments were foliar spray of deionized water only (control), foliar spray of unirradiated chitosan (40 mg L-1), and ICN at 40, 80, 120, and 160 mg L-1. Among these, 80 mg L-1 ICN (treatment 4) proved to be the best for most …

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Microrna-34a Regulates Brain-Derived Neurotrophic Factorin An Intracerebral Hemorrhage Model, Jin Hee Kim, Jae-Sun Choi Jan 2017

Microrna-34a Regulates Brain-Derived Neurotrophic Factorin An Intracerebral Hemorrhage Model, Jin Hee Kim, Jae-Sun Choi

Turkish Journal of Biology

Intracerebral hemorrhages (ICHs) are devastating neurological events frequently resulting in a serious negative prognosis. The exact physiological and disease processes involved in ICHs are complex, but are thought to involve microRNAs (miRNAs), 22 nucleotide small noncoding RNAs that control a variety of normal physiological and disease processes. In this study, we show that a miRNA, miR-34a, regulates BDNF in a model of ICH injury. In particular, we assessed the impact of AM34a, an inhibitor of miR-34a, on the toxicity of thrombin-induced apoptosis and on BDNF-mediated signaling. We investigated the increased expression of miR-34a after an ICH-induced thrombin toxicity injury using …

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The Role Of Predicted Spermidine Family Transporters In Stressresponse And Cell Cycle In Schizosaccharomyces Pombe, Aslihan Gevrekci̇ Jan 2017

The Role Of Predicted Spermidine Family Transporters In Stressresponse And Cell Cycle In Schizosaccharomyces Pombe, Aslihan Gevrekci̇

Turkish Journal of Biology

Fission yeast Schizosaccharomyces pombe has a variety of stress-signaling proteins that protect cells against environmental or intracellular stress. These proteins help the cells to respond to stress conditions and regulate intracellular functions such as cell division or gene expression. Polyamines (spermidine, spermine, and putrescine) are known to be important in the regulation of stress response and cell division. In this study, we tried to experimentally characterize novel S. pombe genes that are involved in the polyamine pathway and understand their potential roles. Sequence analysis revealed four genes that code for (predicted) spermidine family transporters in S. pombe. In an attempt …

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Histomorphometric Evaluation Of The Testicular Parenchyma Of Rats Submittedto Protein Restriction During Intrauterine And Postnatal Life, Jessica Oliveira, Alluanan Silva, Sandra Souza, Rosana Morais, Elizabeth Neves Melo, Frederico Maia, Valdemiro Silva Junior Jan 2017

Histomorphometric Evaluation Of The Testicular Parenchyma Of Rats Submittedto Protein Restriction During Intrauterine And Postnatal Life, Jessica Oliveira, Alluanan Silva, Sandra Souza, Rosana Morais, Elizabeth Neves Melo, Frederico Maia, Valdemiro Silva Junior

Turkish Journal of Biology

The critical period of development is highly susceptible to disorders. Environmental contaminants, stress, and poor nutrition may permanently affect structurally and functionally an organism during adulthood. Protein restriction in intrauterine and neonatal periods may impair testicular cells and reduce steroidogenic activity. The current study investigated the effect of low protein diet during intrauterine and postnatal life on testicular function in immature and adult rats. Pregnant Wistar rats were fed either a normal protein diet or a low protein diet during pregnancy until birth and during lactation until weaning. The results showed that undernutrition during intrauterine life reduced epithelium height, tubular …

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Reference Gene Expression In Human Osteosarcoma Cell Lines Treated By Egb And Ctx, Ming Ren, Qiwei Yang, Yuanyuan Song, Ao Wang, Qingyu Wang, Xiaonan Wang, Shuhong Hao, Zhitao Wang, Zhenwu Du, Guizhen Zhang, Jincheng Wang Jan 2017

Reference Gene Expression In Human Osteosarcoma Cell Lines Treated By Egb And Ctx, Ming Ren, Qiwei Yang, Yuanyuan Song, Ao Wang, Qingyu Wang, Xiaonan Wang, Shuhong Hao, Zhitao Wang, Zhenwu Du, Guizhen Zhang, Jincheng Wang

Turkish Journal of Biology

The selection of stably expressed reference genes is crucial for quantitative real-time polymerase chain reaction (qRT-PCR) assay when assessing osteosarcoma treated with cyclophosphamide (CTX) and Ginkgo biloba L. extract (EGB). We aimed to identify the reference genes that are stably expressed in human osteosarcoma cell lines after the above treatments. We used qRT-PCR assay to determine the expression levels of 18S, ACTB, ALAS1, GAPDH, TBP, HPRT1, RPL29, HMBS, PPIA, PUM1, GUSB, and B2M in the cell lines MG-63, Saos-2, and U2OS, which were treated with CTX or EGB or both. We analyzed the expression stability of these genes using geNorm, …

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Autoregulation Of The Glial Gene Reversed Polarity In Drosophila Melanogaster, Chase Suiter Jan 2017

Autoregulation Of The Glial Gene Reversed Polarity In Drosophila Melanogaster, Chase Suiter

Honors Theses

Autoregulation is the process where an encoded protein is able to bind to and positively or negatively regulate its own expression. Autoregulatory loops are crucial for sustained gene expression, and such loops have been demonstrated to be important for development in organisms ranging from Danio rerio to Arabidopsis thaliana and Drosophila melanogaster. The cells of the nervous system arise from progenitor cells that eventually adopt one of two fates: neuronal or glial. This decision is controlled by glial cells missing; however glial cells missing is expressed briefly at the beginning development. The glial gene repo is a gene that is …

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Geo 4850 : Environmental Geology, Geology/Geography Jan 2017

Geo 4850 : Environmental Geology, Geology/Geography

Approved Course Proposals

No abstract provided.

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Pls 4763 : Environmental Politics & Policy, Political Science Jan 2017

Pls 4763 : Environmental Politics & Policy, Political Science

Approved Course Proposals

No abstract provided.

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Psy 3450 : Neuropsychology, Psychology Jan 2017

Psy 3450 : Neuropsychology, Psychology

Approved Course Proposals

No abstract provided.

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Bio 4835 : Advanced Neurobiology, Biological Sciences Jan 2017

Bio 4835 : Advanced Neurobiology, Biological Sciences

Approved Course Proposals

No abstract provided.

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Bio 2002g : Environmental Life Sciences, Biological Sciences Jan 2017

Bio 2002g : Environmental Life Sciences, Biological Sciences

Approved Course Proposals

No abstract provided.

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Bio 1550g : General Biology Ii, Biological Sciences Jan 2017

Bio 1550g : General Biology Ii, Biological Sciences

Approved Course Proposals

No abstract provided.

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The Effect Of Team-Based Learning In A Neurorehabilitation Course Within A Physical Therapy Assistant Academic Program, Laurie A. Schroder Jan 2017

The Effect Of Team-Based Learning In A Neurorehabilitation Course Within A Physical Therapy Assistant Academic Program, Laurie A. Schroder

Student Dissertations

No abstract provided.

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Emergency Department Use Among Asian Adults Living In The United States: Results From The National Health Interview Survey (2006 – 2013), Kathleen M. Sullivan, James Davis, Angela Sy Jan 2017

Emergency Department Use Among Asian Adults Living In The United States: Results From The National Health Interview Survey (2006 – 2013), Kathleen M. Sullivan, James Davis, Angela Sy

Asian/Pacific Island Nursing Journal

This paper presents secondary analyses of the National Health Interview Survey data focused on emergency department (ED) utilization among Asian adults residing in the United States. National Health Interview Survey data provided from survey years 2006-2013 was pooled and disaggregated by single-race Asian ethnic subgroups (Filipino, Chinese, Asian Indian, other Asian). We explored trends in reports of an ED visit over the survey years for the purpose of determining whether reports of an ED visit increased or decreased over survey years. We also explored background/biologic, environment, access to care, and behavior factors and their associations with having an ED visit. …

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Do Step- And Biological Grandparents Show Differences In Investment And Emotional Closeness With Their Grandchildren?, Peter B. Gray, Elizabeth Brogdon Jan 2017

Do Step- And Biological Grandparents Show Differences In Investment And Emotional Closeness With Their Grandchildren?, Peter B. Gray, Elizabeth Brogdon

Anthropology Faculty Research

Human children are raised by a variety of caregivers including grandparents. A few studies have assessed potential differences in direct caregiving, financial expenditures, and emotional closeness between biological and step-grandparents. Drawing upon kin selection theory, we hypothesized that step-grandparents would provide less care and be less emotionally close to grandchildren than would biological grandparents. A sample of 341 heterosexual U.S. adults 25-35 years of age in a long-term partnership and with a biological child 5 years of age or younger were recruited via Amazon Mechanical Turk. Subjects provided sociodemographic information and answered questions about the dynamics between their own parent/stepparent …

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Valuing Sacred Tribal Waters Within Prior Appropriation, Michelle Bryan Jan 2017

Valuing Sacred Tribal Waters Within Prior Appropriation, Michelle Bryan

Faculty Law Review Articles

Throughout the world water plays a central role in the spirituality of indigenous peoples. Focusing on the American West, this article first describes how tribal water needs touch upon the sacred and then explains how both federal law and state prior appropriation doctrine fail to adequately protect these important sacred views of water. Pivoting away from the classic federal law arguments, the article then advocates for an evolution in state water law regimes to provide yet unrecognized protections for tribal sacred waters. Because international law plays an increasing role in this issue, the article also explores case studies from Ireland, …

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Biometrics: The Future Is In Your Hands, Kelsey Sherman Jan 2017

Biometrics: The Future Is In Your Hands, Kelsey Sherman

Loyola of Los Angeles Law Review

No abstract provided.

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E2f Transcription Factor 1 And Its Role In The Cell Cycle And Tumor Suppressor Proteins, Thea Hisuler, Yu Kuang Jan 2017

E2f Transcription Factor 1 And Its Role In The Cell Cycle And Tumor Suppressor Proteins, Thea Hisuler, Yu Kuang

AANAPISI Poster Presentations

E2F Transcription Factor 1 (E2F1) E2F1 is a transcription factor, in which its expression is increased in human cancers. “Transcription factor E2F1 binds to and activates transcription,” in return leading to increased transcription at the G1 and S phase of the cell cycle (Slansky). The E2F transcription factor family “plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses” (NCBI).

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Synthetic Melanin Films As Potential Interfaces For Peroxynitrite Detection And Quantification, Haitham F. Kalil, Shaimaa Mahera, Tiyash Bosed, Ousama Al-Mahmoude, Clara Kay, Mekki Bayachou Jan 2017

Synthetic Melanin Films As Potential Interfaces For Peroxynitrite Detection And Quantification, Haitham F. Kalil, Shaimaa Mahera, Tiyash Bosed, Ousama Al-Mahmoude, Clara Kay, Mekki Bayachou

Chemistry Faculty Publications

Peroxynitrite (PON) is a highly reactive oxygen-nitrogen species that facilitates both oxidation and nitration reactions. Early reports have revealed the deleterious effects of PON on DNA, proteins, and lipids. Recent studies have suggested that melanin can act as an antioxidative therapy to scavenge the reactive oxygen-nitrogen species (RO-NS) including PON. Melanin is a natural pigment that has many physiological functions involving the neutralization of highly oxidative species. In this project, the interaction between PON and synthetic melanin has been studied. In addition, the electrochemical characteristics of the polymerized 5,6-dihydroxy indole (DHI) as a model of synthetic melanin were examined using …

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Annual Report 2017, Nebraska Center For Justice Research, University Of Nebraska At Omaha, Ryan E. Spohn Jan 2017

Annual Report 2017, Nebraska Center For Justice Research, University Of Nebraska At Omaha, Ryan E. Spohn

Reports

The Nebraska Center for Justice Research (NCJR) was established in 2014 with a mission to develop and sustain criminal justice research capacity internal to the State of Nebraska. Our goal is to assist the Legislature, justice agencies, practitioners, foundations, and stakeholders with research and evaluation to reduce recidivism, promote the use of evidence-based practices, and improve public safety. This annual report summarizes the activities and financial status of NCJR in its third year. In the 2016-2017 fiscal year, NCJR once again crafted our Adult Justice in Nebraska report to provide a foundation of data trends in areas such as law …

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An Exploratory Analysis Of Psychological And Genetic Based Outcomes Related To Binge Drinking And Binge Eating Behaviors In A College-Age Population, Carley Garris Lovell Jan 2017

An Exploratory Analysis Of Psychological And Genetic Based Outcomes Related To Binge Drinking And Binge Eating Behaviors In A College-Age Population, Carley Garris Lovell

MUSC Theses and Dissertations

Purpose: The purpose of this dissertation was to explore psychological and genetic associations of binge drinking and eating in college-age individuals, and to assess if overlap exists across phenotypes. Key contributing factors of binge drinking and binge eating informed the development of a hypothesized biobehavioral conceptual framework for binge behavior. Next, an integrative review of existing instruments that measure binge eating was conducted to observe concepts related to binge eating as applied clinically. Finally, a secondary analysis was carried out to investigate the phenotypes of interest in a study aim that focused on key concepts in the framework from survey …

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City Of Gresham Stormwater Retrofit Master Plan, Teresa F. Huntsinger Jan 2017

City Of Gresham Stormwater Retrofit Master Plan, Teresa F. Huntsinger

Civil and Environmental Engineering Master's Project Reports

The Stormwater Retrofit Master Plan identifies more than 50 stormwater retrofit project opportunities across three watersheds in the City of Gresham. The retrofit projects are prioritized in a scoring system to evaluate the costs and benefits of diverse project sizes and types. Project types range from bioswales and planters in city parking lots and along arterial roads, to regional end-of-pipe facilities and retrofits of existing detention ponds. Top projects will move forward for further assessment, design and construction, helping the city achieve its water quality improvement goals. The scoring system may be used to evaluate additional projects in the future.

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De-Policing, Stephen Rushin, Griffin Sims Edwards Jan 2017

De-Policing, Stephen Rushin, Griffin Sims Edwards

Faculty Publications & Other Works

Critics have long claimed that when the law regulates police behavior it inadvertently reduces officer aggressiveness, thereby increasing crime. This hypothesis has taken on new significance in recent years as prominent politicians and law enforcement leaders have argued that increased oversight of police officers in the wake of the events in Ferguson, Missouri has led to an increase in national crime rates. Using a panel of American law enforcement agencies and difference-in-difference regression analyses, this Article tests whether the introduction of public scrutiny or external regulation is associated with changes in crime rates. To do this, this Article relies on …

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Social Justice And Capitalism: An Assessment Of The Teachings Of Pope Francis From A Law And Macroeconomics Perspective, Steven A. Ramirez Jan 2017

Social Justice And Capitalism: An Assessment Of The Teachings Of Pope Francis From A Law And Macroeconomics Perspective, Steven A. Ramirez

Faculty Publications & Other Works

No abstract provided.

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Diversity, Compliance, Ethics & In-House Counsel, Steven A. Ramirez Jan 2017

Diversity, Compliance, Ethics & In-House Counsel, Steven A. Ramirez

Faculty Publications & Other Works

No abstract provided.

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Cultivating Innovation In Precision Medicine Through Regulatory Flexibility At The Fda, Jordan Paradise Jan 2017

Cultivating Innovation In Precision Medicine Through Regulatory Flexibility At The Fda, Jordan Paradise

Faculty Publications & Other Works

No abstract provided.

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Social Justice And The American Law School Today: Since We Are Made For Love, Michael J. Kaufman Jan 2017

Social Justice And The American Law School Today: Since We Are Made For Love, Michael J. Kaufman

Faculty Publications & Other Works

No abstract provided.

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Moving In Opposite Directions? Exploring Trends In Consumer Demand And Agricultural Production, Susan A. Schneider Jan 2017

Moving In Opposite Directions? Exploring Trends In Consumer Demand And Agricultural Production, Susan A. Schneider

Mitchell Hamline Law Review

No abstract provided.

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