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The Integration Of Music In An Ela Classroom: Creating Pedagogical Parodies For Elementary Education, Doranna Smith

Honors Undergraduate Theses

The intent of this thesis is to capitalize the effects of using music as a tool in tandem with English language arts in order for students to improve their ELA skills. Songs are already flooding the Internet and social media; such as Facebook, Instagram, Twitter, and Vine, echoing in the background of television broadcasts and commercials, and blasting across radio stations and in public areas like restaurants and malls, classroom lessons tied to current songs, are more apt to resonate with students in this era. In lieu of subconsciously humming a song by popular artist such as Beyoncé, Kanye West, …

Validating Drug Targets Through Inhibition Of Protein-Protein Interactions In Mycobacterium Tuberculosis, Erin C. Driscoll

Honors Undergraduate Theses

Tuberculosis is the leading cause of death by single infectious disease worldwide; novel antibiotics are needed to continue to treat this disease. To goal of this project is to provide proof-of-principle support for the idea that targeting protein-protein interactions (PPI) is an appropriate course for the discovery of new drugs. This study optimized the M-PFC assay, which allows detection of PPI in Mycobacteria, through the use of stronger promoters and inducible expression of a peptide blocker by riboswitch. To accomplish this, promoter induction studies were used to find stronger promoters for the M-PFC, optimization of the riboswitch as a …

Testing Of Wrist-Worn-Fitness-Tracking Devices During Cognitive Stress: A Validation Study, Nicole S. Chudy

Honors Undergraduate Theses

The intent of this thesis was to test if one of the many fitness-tracking devices, Microsoft’s Band 2 (MSB2), is accurate and reliable in detecting changes in Heart Rate (HR) and R-R intervals, during the repeated trial of two conditions of a working-memory test known as the N-Back. A 2 (devices: ECG, MSB2) × 4 (epochs: baseline 1, 1-back task, baseline 2, 3-back task) repeated measures factorial design was conducted. The participants were simultaneously equipped to the MSB2 and an electrocardiogram (ECG). The results of this study validated the MSB2 for the use in a cognitive task. The study suggests …

A Structural And Functional Analysis Of Human Brain Mri With Attention Deficit Hyperactivity Disorder, Arjun A. Watane

Honors Undergraduate Theses

Attention Deficit Hyperactivity Disorder (ADHD) affects 5-10% of children worldwide. Its effects are mainly behavioral, manifesting in symptoms such as inattention, hyperactivity, and impulsivity. If not monitored and treated, ADHD may adversely affect a child's health, education, and social life. Furthermore, the neurological disorder is currently diagnosed through interviews and opinions of teachers, parents, and physicians. Because this is a subjective method of identifying ADHD, it is easily prone to error and misdiagnosis. Therefore, there is a clear need to develop an objective diagnostic method for ADHD.

The focus of this study is to explore the use of machine language …

Using Low-Coherence Interferometry To Monitor Cell Invasion In An In-Vitro Model System, Behnaz Davoudi Nasab

Honors Undergraduate Theses

In an optically random system, such as naturally occurring and man-made media, light undergoes pronounced multiple scattering. This phenomenon has shown a remarkable potential in characterizing complex materials. In this regime, scattering occurs from each individual center of the scattering and independent scattering events lead to multiple light scattering. This phenomenon is often described as a random walk of photons and can be modeled in terms of a diffusion equation based on the radiative transfer theory. In this thesis, we used optical path-length spectroscopy (OPS), which is an experimental method to obtain the path-length probability density of the propagating light …

Evaluating The Quality Of Physical Education Programs Provided By State Department Of Education Websites And The Relationships Between Adolescent Obesity And Sedentary Prevalence, Payton C. Mcwilliams

Honors Undergraduate Theses

This research seeks to determine the relationships between the quality of physical education (PE) programs provided by state departments of education (DOE), obesity rates, and sedentary behaviors described as physical inactivity in adolescents ages 10-17 years old. A modified rubric based on the “Let’s Move Active Schools Assessment” was created and used to quantitatively and qualitatively evaluate the PE programs and physical activity (PA) opportunities provided by websites of the state’s DOE. A total of fourteen states were chosen to be assessed due to having either the highest or lowest obesity or physical inactivity rates. It was believed that the …

Unplugging: A Parent's Handbook For Children's Technology Use, Victoria R. Taylor

Honors Undergraduate Theses

The intent of this thesis is to explore children’s technology usage, technology’s effects, and what can be done to regulate technology use for children and families. The overuse of technology by children has been proven to be detrimental to a child’s emotions and health and wellness. Children need rules and regulations for proper use of technology as well as instruction on how to positively use technology. In a world of growing technologies and the creation of new digital devices, research is needed for assist parents and guardians of children of all ages. This thesis focuses on the negative effects of …

Power Distribution Of Terahertz Emission From Hexagonal Bscco Microstrip Antennas, Andrew E. Davis

Honors Undergraduate Theses

We analyze the distribution of coherent terahertz radiation from a regular hexagonal microstrip antenna (MSA) made from the high-T_c superconductor Bi₂Sr₂CaCu₂O_8+x (BSCCO). We discuss the C_6v symmetry of the solutions of the wave equation on a hexagonal domain and distinguish between the closed-form and non-closed-form solutions. The closed-form wavefunctions of the transverse magnetic (TM) electromagnetic cavity modes are presented and formulas for the radiated power arising from the uniform part of the AC Josephson current and from the resonant cavity modes are derived. The wavefunctions and angular distribution of radiation from …

Literature Review On The Use Of Nucleic Acid-Based Logic Gates For The Detection Of Human Diseases, Enrique J. Blanco Martinez

Honors Undergraduate Theses

Conventional methods for diagnosis of human disease are, at times, limited in different regards including time requirement, either experimental or data processing, sensitivity, and selectivity. It is then that a Point of Care Criteria, which considers the true utility and usefulness of the device, is employed to propose new diagnostic devices capable of overcoming the aforementioned shortcomings of conventional tools. Nucleic acid, characterized for its predictable base-pairing nature, is considered to be a highly-selective, yet greatly modifiable device. Its behavior is then described through Boolean Logic, where “true” or “false” outputs are mathematically described as “1” and “0”, respectively. This …

Receptive And Expressive Single Word Vocabulary Errors Of Preschool Children With Developmental Disabilities, Juliana L. Hirn

Honors Undergraduate Theses

Vocabulary growth during the preschool years is critical for language development. Preschool children with developmental disabilities often have more difficulty with learning and developing language, therefore making more errors in vocabulary. It is important to recognize what type of errors children are demonstrating, especially as it relates to receptive and expressive language abilities. This study explores the error patterns preschool children with developmental disabilities make during receptive and expressive single word vocabulary tests. A secondary analysis of preexisting data was conducted from a sample of 68 preschool children with developmental disabilities ranging in severity. Based on a coding system developed …

Activation And Expansion Of Natural Killer Cells For Cancer Immunotherapy With Ex21 Exosomes, Sara Khederzadeh

Honors Undergraduate Theses

In the field of cancer immunotherapy, NK cells are recognized for their ability to provide a form of innate immunity against tumor cells. However, the average abundance of NK cells in the blood can be as low as 5% of the total lymphocyte population. As a result, it has been a focus to find novel therapies to expand NK cells in vitro while subsequently enhancing the cytotoxicity of these cells. Previously-defined methods include the minimal expansion of NK cells with high levels of cytokines such as IL-2 and IL-15, as well as co-culturing NK cells with feeder cell populations that …

Identifying The Effects Of A Human Dynein Mutation On Gfp-Rab7 Axonal Transport In Embryonic Mouse Neurons, Natalie E. Wilson

Honors Undergraduate Theses

The first dynein mutation found in humans that caused disease was a cytoplasmic dynein 1 heavy chain (DYNC1H1 in humans) p.His306Arg mutation, first described by Weedon et al. in 2011. This mutation caused Charcot-Marie-Tooth (CMT) subtype 2O. CMT has a prevalence of approximately 1 in 2500 people, making it the most common hereditary neuromuscular disorder. Cytoplasmic dynein 1 is used by eukaryotic cells for minus-end directed microtubule-based transport of cargo. One such cargo is Rab7, a late endosomal marker. The purpose of this study is to identify the effects of this mutation on the transport of GFP-tagged Rab7 cargo in …

Atmospheric Entry, Dillon A. Martin

Honors Undergraduate Theses

The development of atmospheric entry guidance methods is crucial to achieving the requirements for future missions to Mars; however, many missions implement a unique controller which are spacecraft specific. Here we look at the implementation of neural networks as a baseline controller that will work for a variety of different spacecraft. To accomplish this, a simulation is developed and validated with the Apollo controller. A feedforward neural network controller is then analyzed and compared to the Apollo case.

Micro-Spectroscopy Of Bio-Assemblies At The Single Cell Level, Jeslin Kera

Honors Undergraduate Theses

In this thesis, we investigate biological molecules on a micron scale in the ultraviolet spectral region through the non-destructive confocal absorption microscopy. The setup involves a combination of confocal microscope with a UV light excitation beam to measure the optical absorption spectra with spatial resolution of 1.4 μm in the lateral and 3.6 μm in the axial direction. Confocal absorption microscopy has the benefits of requiring no labels and only low light intensity for excitation while providing a strong signal from the contrast generated by the attenuation of propagating light due to absorption. This enables spatially resolved measurements of single …

Advanced Castes At The Outset Of Eusociality In Wasps (Vespidae), Patrick Piekarski

Electronic Theses and Dissertations

A dominating and widespread view is that evolutionary change is gradual and waits upon mutation. Likewise, it is thought that workers and queens of eusocial insects diverged gradually and stepwise. That is, rudimentary castes preceded advanced castes. This paradigm hinges on eusociality having evolved once in Vespidae, and primitively eusocial paper wasps lacking ontogenetic caste biasing (differentiation of castes during larval development). Using a phylogenomic approach this study shows strong evidence for two origins of eusociality in vespid wasps, wherein one origin is likely characterized by the sudden appearance of castes with physiological, and perhaps even morphological, differences established before …

Assessment Of Physical Workload, Ergonomic Problems And Prevalence Of Pain Among Low Wage Hotel Housekeepers In Orlando, Rachel Mammen

Electronic Theses and Dissertations

This research study examined the work conditions, ergonomic problems, and prevalence of pain among low wage hotel room cleaners in Orlando. In most hotels, the cleanliness of guestrooms is one of the most important service standards expected by customers. The role of the housekeeper is thus critical to service provision and hotel profitability. The hospitality industry is a major recruiter of low wage workers with the majority working in housekeeping departments. Due to the nature of the research problem, a positivist quantitative approach was adopted although the survey instrument included space for qualitative comments to some of the latter open-ended …

Mesoscopic Interactions In Complex Photonic Media, Roxana Rezvani Naraghi

Electronic Theses and Dissertations

Mesoscale optics provides a framework for understanding a wide range of phenomena occurring in a variety of fields ranging from biological tissues to composite materials and from colloidal physics to fabricated nanostructures. When light interacts with a complex system, the outcome depends significantly on the length and time scales of interaction. Mesoscale optics offers the apparatus necessary for describing specific manifestations of wave phenomena such as interference and phase memory in complex media. In-depth understanding of mesoscale phenomena provides the required quantitative explanations that neither microscopic nor macroscopic models of light-matter interaction can afford. Modeling mesoscopic systems is challenging because …

Posttraumatic Stress Disorder Or Combat Experience? A Functional Near-Infrared Spectroscopy Study Of Trauma-Related Auditory And Olfactory Cues, Michael Gramlich

Electronic Theses and Dissertations

While the clinical communities are aware of the prevalence of posttraumatic stress disorder (PTSD) among OEF/OIF/OND veterans, further efforts are necessary to bolster comprehensive strategies for assessment and treatment. The purpose of this study was to investigate whether a combat-related PTSD symptom provocation paradigm would elicit unique neurological responses via functional near-infrared spectroscopy across three groups – combat veterans with PTSD, combat veterans without PTSD, and nonmilitary participants without PTSD. Results indicated that combat veterans with PTSD demonstrated significant activation during exposure to a trauma-related sound compared to nonmilitary personnel at channels 14 (d = 1.03) and 15 (d = …

Effects Of An Acute High-Volume Isokinetic Intervention On Inflammatory And Strength Changes: Influence Of Age, Joseph Gordon

Electronic Theses and Dissertations

PURPOSE: The purpose of this study was to compare the effects of a high volume isokinetic intervention on lower body strength and inflammation, as well as markers of muscle damage in the subsequent 48 hours between younger and middle-aged men. METHODS: 19 healthy, recreationally trained men were randomly assigned to two groups, younger adults (YA: 21.8 ± 2.0 y; 90.7 ± 11.6 kg; 21.5 ± 4.1 % body fat), or middle-aged adults (MA: 47.0 ± 4.4 y; 96.0 ± 21.5; 24.8 ± 6.3 % body fat). Both groups reported to the human performance laboratory (HPL) on four separate occasions. On …

An Anthropological Study Of Eating Perspectives, Meal Composition, And Food Choices Among Diverse Student Populations, Chelsea Daws

Electronic Theses and Dissertations

My thesis explores the factors that shape or reinforce international college students' perceptions of food. This research not only examines how cultural values affect individual nutrition and maintenance of eating behaviors, it also addresses the extent to which accessibility impacts eating behaviors. Notably, the research endeavor uses the concept of dietary habitus as an underlying directive mechanism for study. This study finds that most students experience a reduction in their fruit and vegetable intake. Another finding suggests that international students eat healthier and are more structured in comparison to domestic students if they hybridize their dietary habitus. Research findings also …

Probation Officer Productivity: Using The Effort-Reward Imbalance Model, Brandon Presley

Electronic Theses and Dissertations

The purpose of this study is to determine the extent to which workplace efforts and rewards are associated with probation officer stress, overcommitment, health, and productivity. This research uses the effort-reward imbalance model, which is an indicator of job stress, on a group of criminal justice probation officers. The probation officers completed questionnaires regarding their perceptions of health, perceived reward, perceived effort, perceptions of overcommitment, and perceived productivity. Afterward, the responses were collected, and analyses were conducted using correlation and multiple regression to determine the extent to which perceptions of effort, reward, and overcommitment effect probation officer productivity and health. …

Data Representation In Machine Learning Methods With Its Application To Compilation Optimization And Epitope Prediction, Yevgeniy Sher

Electronic Theses and Dissertations

In this dissertation we explore the application of machine learning algorithms to compilation phase order optimization, and epitope prediction. The common thread running through these two disparate domains is the type of data being dealt with. In both problem domains we are dealing with categorical data, with its representation playing a significant role in the performance of classification algorithms. We first present a neuroevolutionary approach which orders optimization phases to generate compiled programs with performance superior to those compiled using LLVM's -O3 optimization level. Performance improvements calculated as the speed of the compiled program's execution ranged from 27% for the …

An Sos Conceptual Model, Lvc Simulation Framework, And A Prototypical Implementation Of Unmanned System Interventions For Nuclear Power Plant Disaster Preparedness, Response, And Mitigation, Matthew Davis

Electronic Theses and Dissertations

Nuclear power plant disasters can have severe and far-reaching consequences, thus emergency managers and first responders from utility owners to the DoD must be prepared to respond to and mitigate effects protecting the public and environment from further damage. Rapidly emerging unmanned systems promise significant improvement in response and mitigation of nuclear disasters. Models and simulations (M&S) may play a significant role in improving readiness and reducing risks through its use in planning, analysis, preparation training, and mitigation rehearsal for a wide spectrum of derivate scenarios. Legacy nuclear reactor M&S lack interoperability between themselves and avatar or agent-based simulations of …

Predicting Child Maltreatment Potential In Mothers Who Are Substance-Involved: A Study Of Childhood Adversity, Stress, Affectivity, Emotion Dysregulation, And Emotion Regulation Strategies As Mechanisms Of Action, Amanda Lowell

Electronic Theses and Dissertations

Compared to the general population, parents who are substance-involved are both more likely to have experienced adversity during childhood and to exhibit elevated child maltreatment potential later in life. Within this population, mothers with young children are particularly at-risk. In order to enhance scientific understanding of this phenomenon, this study identified and examined several characteristics that were shown previously to be related to substance misuse and to the experience and perpetration of maltreatment. These characteristics included stress, affectivity, emotion dysregulation, and emotion regulation strategies. The current study examined these variables collectively in order to clarify the mechanisms at play in …

The Effects Of Social Support And Working Alliance On Latino-American Male Combat Veterans, Lloyd Duran

Electronic Theses and Dissertations

The negative effects of traumatic combat experiences on combatants' psychological functioning is well documented in the literature. The Global War on Terrorism (GWOT) has resulted in many veterans returning from deployments with mental health conditions related to trauma exposure, such as posttraumatic stress disorder, depression, general anxiety, and suicidality. Past researchers found significant ethnic differences in psychological functioning, with Latino-American veterans reporting more symptoms of PTSD. Furthermore, Latino-American cultural values place importance on collective orientation and secrecy of mental health concerns which may affect treatment. Thus, this study built on limited research about Latino-American male combat veterans by focusing on …

Consequences Of Altered Short-Chain Carbon Metabolism In Heart Failure, Julie Horton

Electronic Theses and Dissertations

Cardiovascular disease is currently the foremost cause of death within the United States. Heart failure (HF) is a syndrome defined by the inability of the heart to adequately execute requisite pump function in order to deliver nutrients and oxygen to peripheral tissues, irrespective of etiology. One of the most common causes of HF is chronic pressure overload due to hypertension. Ischemic heart disease is also a common driver of HF, often in conjunction with hypertension. Pressure overload initially causes compensatory metabolic changes. Structural changes follow shortly thereafter typically resulting in left ventricular hypertrophy. Eventually, the heart loses the ability to …

Go With The Flow: Patterns Of Connectivity In Low Dispersal Coral Reef Gobies (Coryphopterus Spp.) Throughout The Western Atlantic, Daniel Volk

Electronic Theses and Dissertations

Gene flow is an integral biological process that can mediate speciation. While many consider the ocean to be an open environment, there are many barriers that limit gene flow, particularly in the western Atlantic. I analyzed data from two widespread, coral reef fishes, the bridled goby (Coryphopterus glaucofraenum) and sand-canyon goby (C. venezuelae), throughout their range in the western Atlantic. Using two genetic datasets, mitochondrial DNA (mtDNA) and genomic SNPs, I investigated the evolutionary history of these species and inferred the location and strength of putative barriers. My results suggest that several unique lineages have genetically diverged from one another …

The Paths Less Traveled: Movement Of Gopher Tortoises Along Roads And Railways, Rhett Rautsaw

Electronic Theses and Dissertations

Urbanization and an expanding human population have led to a large degree of habitat destruction and fragmentation. These, in turn, reduce biodiversity and wildlife population sizes on a global scale. Transportation infrastructure, such as roads and railways, are some of the largest contributors to habitat fragmentation. Roads are well-established to negatively impact wildlife, but some studies suggest a potential use in habitat connectivity by functioning as wildlife corridors to connect distant populations. Railways are similarly known to impact wildlife by increasing mortality rates as well as provide unique risks such as electrocution and entrapment when compared to roads. However, the …

Two-Component Covalent Inhibitors (Tcci) Of The Human Immunodeficiency Virus Reverse Transcriptase (Hiv-Rt), Carlos Ledezma

Electronic Theses and Dissertations

The traditional design of nucleoside reverse transcriptase inhibitors (NRTI's) involves the synthesis of chain-terminated nucleoside analogs. HIV-RT has relatively low fidelity which facilitates mutations that confer resistance towards NRTI's, also, drug promiscuity from NRTI's result in various side-effects that lead to poor patient adherence to treatment. We designed and tested two-component covalent inhibitors against HIV-RT. Our inhibitor design results in higher specificity due to its binary approach, which has previously been used in biosensing applications, where both components are necessary for therapeutic effect, and lower chances for mutagenesis because of its inhibitory action. The TCCI approach results in up to …

The Impact Of Automation And Stress On Human Performance In Uav Operation, Jinchao Lin

Electronic Theses and Dissertations

The United States Air Force (USAF) has increasing needs for unmanned aerial vehicle (UAV) operators. Automation may enable a single operator to manage multiple UAVs at the same time. Multi-UAV operation may require a unique set of skills and the need for new operators calls for targeting new populations for recruitment. The objective of this research is to develop a simulation environment for studying the role of individual differences in UAV operation under different task configurations and investigate predictors of performance and stress. Primarily, the study examined the impact of levels of automation (LOAs), as well as task demands, on …