Digital Commons Network^™

Is The Eccc’S Supreme Court Chamber’S Conception Of A Common Criminal Plan In The Case 002/01 Appeal Judgment Supported By Customary International Law? Specifically Addressing The Arguments Surrounding The Supreme Court Chamber’S Rejection Of The Existence Of Jce3 And Whether Post World War Ii Jurisprudence Establishes The Existence Of Jce3 In Customary International Law., Jordan Elizabeth Dinsmore

War Crimes Memoranda

No abstract provided.

Rhetorical Commonsense And Child Molester Panic--A Queer Intervention, Ian Barnard

English Faculty Articles and Research

This article considers how contemporary representations of child molesters in scholarly, political, and popular culture participate in projects that revolve around the recuperation of heteronormativity. I argue that these multimodal obsessions with child molestation displace the resilience of entrenched homophobic fears, prejudices, and dispositions, giving the lie to the commonplace that the political advance of same-sex marriage in the United States signals the apotheosis of gay rights. My analysis focuses on two representative popular and scholarly texts: the long-running television series Law and Order: SVU and a scholarly article about the Jerry Sandusky case published in jac. The former …

Importance Of Maintaining The Diverse Tallgrass Prairie, Shelley Kosola

Sustainable RIVER

No abstract provided.

Impact Of Drought On Suspended Load In South Dakota Tributaries, Bethany Vazquez

Sustainable RIVER

No abstract provided.

Effects Of Fish On Aquatic Insects, Tyler Seidel

Sustainable RIVER

No abstract provided.

A Novel Design Of A Phase Iii Trial Of Isradipine In Early Parkinson Disease (Steady-Pd Iii), Kevin M. Biglan, David Oakes, Anthony E. Lang, Robert A. Hauser, Karen Hodgeman, Brittany Greco, Jillian Lowell, Rebecca Rockhill, Ira Shoulson, Charles Venuto, Diony Young, Tanya Simuni

Neurology Faculty Publications

Objectives To describe the rationale for a novel study design and baseline characteristics of a disease-modifying trial of isradipine 10 mg daily in early Parkinson disease (PD).

Methods STEADY-PDIII is a 36-month, Phase 3, parallel group, placebo-controlled study of the efficacy of isradipine 10 mg daily in 336 participants with early PD as measured by the change in the Unified Parkinson Disease Rating Scale (UPDRS) Part I-III score in the practically defined ON state. Secondary outcome measures include clinically meaningful measures of disability progression in early PD: (1) Time to initiation and utilization of dopaminergic therapy; (2) Time to onset …

Cryptic Biodiversity And Phylogeographic Patterns Of Seychellois Ligia Isopods, Carlos A. Santamaria, Joanna K. Bluemel, Nancy Bunbury, Melinda Curran

Mathematics and Statistics Faculty Publications

Ligia isopods are conspicuous inhabitants of rocky intertidal habitats exhibiting several biological traits that severely limit their dispersal potential. Their presence in patchy habitats and low vagility may lead to long term isolation, allopatric isolation and possible cryptic speciation. Indeed, various species of Ligia have been suggested to represent instead cryptic species complexes. Past studies; however, have largely focused in Eastern Pacific and Atlantic species of Ligia, leaving in doubt whether cryptic diversity occurs in other highly biodiverse areas. The Seychelles consists of 115 islands of different ages and geological origins spread across the western Indian Ocean. They are …

Panel: Influencing Culture And Curriculum Via Revolution, Amit Jain

Computer Science Faculty Publications and Presentations

The goal of this panel session is to introduce audience members to the challenges and successes of significant cultural and curricular change as enacted by awardees in the NSF program Revolutionizing Engineering and Computer Science Departments (RED). This panel will explore how organizations go about the process of cultural investigation and how they embark on culture change, using RED awardees of 2016 as the featured panelists (the second cohort). These teams are engaged in high-risk, high-trust-required activities focused on both the organizational and operational structure of their departments, and on re-envisioning engineering and computer science curricula to create professionals able …

Biotic Changes Around The Radioisotopically Constrained Carboniferous-Permian Boundary In The Boskovice Basin (Czech Republic), Stanislav Oplustil, Jakub Jirásek, Mark Schmitz, Dalibor Matýsek

Geosciences Faculty Publications and Presentations

Presented is an analysis of vegetation patterns across the Carboniferous-Permian boundary in continental setting constrained for the first time in Europe and North America by high-precision U-Pb radioisotopic dating. The analysis is performed on the fossil record of the Boskovice Basin (Czech Republic), a Late Palaeozoic half-graben having ~ 5 km of cumulative thickness. It is dominantly a red bed succession containing numerous grey, mostly lacustrine horizons bearing fairly rich fossil floras and faunas of Late Pennsylvanian to Cisuralian age. U-Pb geochronology on single zircon crystals separated from a volcanic tuff near the top of the Rosice-Oslavany Formation, in the …

The Daily Gamecock, Thursday, January 12, 2017, University Of South Carolina, Office Of Student Media

January

No abstract provided.

Winter Report: December 2016-February 2017, Kevin E. Dailey

Florida Field Naturalist

No abstract provided.

Shadow-Boxing’ By A Northern Mockingbird (Mimus Polyglottos), Corey T. Callaghan

Florida Field Naturalist

No abstract provided.

Hatching Failure In A Florida Population Of House Finches (Haemorhous Mexicanus), Claire Gentile, Christine M. Stracey

Florida Field Naturalist

No abstract provided.

Cover, Florida Field Naturalist

Florida Field Naturalist

No abstract provided.

Front Matter, Florida Field Naturalist

Florida Field Naturalist

No abstract provided.

Spring Report: March-May 2017, Kevin E. Dailey

Florida Field Naturalist

No abstract provided.

Improvised Courtship Feeding By An Osprey (Pandion Haliaetus) Pair, James R. Thomas

Florida Field Naturalist

No abstract provided.

Distinct Transcriptome Profiles Of Gag-Specific Cd8+ T Cells Temporally Correlated With The Protection Elicited By Sivδnef Live Attenuated Vaccine, Wuxun Lu, Yanmin Wan, Fangrui Ma, R. Paul Johnson, Qingsheng Li

School of Biological Sciences: Faculty Publications

The live attenuated vaccine (LAV) SIVmac239Δnef (SIVΔnef) confers the best protection among all the vaccine modalities tested in rhesus macaque model of HIV-1 infection. This vaccine has a unique feature of time-dependent protection: macaques are not protected at 3±5 weeks post vaccination (WPV), whereas immune protection emerges between 15 and 20 WPV. Although the exact mechanisms of the time-dependent protection remain incompletely understood, studies suggested that both cellular and humoral immunities contribute to this time-dependent protection. To further elucidate the mechanisms of protection induced by SIVΔnef, we longitudinally compared the global gene expression profiles of SIV Gag-CM9+ CD8+ (Gag-specific CD8+) …

Protocol For Surveying Bat Use Of Lava Tube Caves During Winter In Craters Of The Moon National Monument And Preserve, Version 1.0, Thomas J. Rodhouse, Kathleen Slocum, Todd Stefanic, Shawn Thomas, Meghan Lonneker, Gordon Dicus

United States National Park Service: Publications

Executive Summary

The mission of the National Park Service (NPS) is “to conserve unimpaired the natural and cultural resources and values of the national park system for the enjoyment of this and future generations” (NPS 1999). To uphold this goal, the Director of the NPS approved the Natural Resource Challenge to encourage national parks to focus on the preservation of the nation’s natural heritage through science, natural resource inventories, and expanded resource monitoring (NPS 1999). Through the Challenge, 270 parks in the national park system were organized into 32 inventory and monitoring (I&M) networks.

The Upper Columbia Basin Network Inventory …

Effects Of Control On The Dynamics Of An Adjacent Protected Wolf Population In Interior Alaska, Joshua H. Schmidt, John W. Burch, Margaret C. Maccluskie

United States National Park Service: Publications

Long-term wolf (Canis lupus) research programs have provided many insights into wolf population dynamics. Understanding the mechanisms controlling responses of wolf populations to changes in density, environmental conditions, and human-caused mortality are important as wolf management becomes increasingly intensive. Competition with humans for ungulate prey has led to large-scale wolf control programs, particularly in Alaska, and although wolf populations may sustain relatively high (e.g., 22–29%) rates of conventional harvest, control programs are specifically designed to have lasting population-level effects.

Understanding the broader impacts of wolf control efforts on the surrounding area is of particular concern for conservation agencies …

Large-Scale Movement Behavior In A Reintroduced Predator Population, Frances E. Buderman, Melvin B. Hooten, Jacob S. Ivan, Tanya M. Shenk

United States National Park Service: Publications

Understanding movement behavior and identifying areas of landscape connectivity is critical for the conservation of many species. However, collecting fine-scale movement data can be prohibitively time consuming and costly, especially for rare or endangered species, whereas existing data sets may provide the best available information on animal movement. Contemporary movement models may not be an option for modeling existing data due to low temporal resolution and large or unusual error structures, but inference can still be obtained using a functional movement modeling approach. We use a functional movement model to perform a population-level analysis of telemetry data collected during the …

Ptsd, Alcohol Dependence, And Conduct Problems: Distinct Pathways Via Lability And Disinhibition, Jeffrey S. Simons, Raluca M. Simons, Carol O'Brien, Scott F. Stoltenberg, Jessica A. Keith, Jaime A. Hudson

Department of Psychology: Faculty Publications

This study tested the role of affect lability and disinhibition in mediating associations between PTSD symptoms and two forms of alcohol-related problems, dependence syndrome symptoms (e.g., impaired control over consumption) and conduct problems (e.g., assault, risk behaviors). Genotype at the serotonin transporter linked polymorphic region (5-HTTLPR) was hypothesized to moderate associations between traumatic stress and PTSD symptoms. In addition, the study tested whether childhood traumatic stress moderated associations between combat trauma and PTSD symptoms. Participants were 270 OIF/OEF/OND veterans. The hypothesized model was largely supported. Participants with the low expression alleles of 5-HTTLPR (S or L_G) exhibited stronger …

The American Pediatric Type 2 Diabetes Epidemic: Considerations For Targeted Diabetes Prevention Programs, Dolores Dodson

Master of Public Health Program Student Publications

Childhood obesity is an identified risk factor for several long-term health issues such as type 2 diabetes mellitus (T2DM). According to the Centers for Disease Control and Prevention (CDC), diabetes is the seventh leading cause of death within the United States. The CDC has implemented an evidence-based program, The National Diabetes Prevention Program (DPP), to prevent the development of T2DM among individuals with prediabetes. Prediabetes is defined as having elevated glucose levels glycated hemoglobin [A1C] levels between 5.7%-6.5%) that are not elevated enough to meet diabetes diagnosis criteria (A1C levels > 6.5%). The DPP is a lifestyle change program that has …

First Definitive Fossil Of An Oestroid Fly (Diptera: Calyptratae: Oestroidea) And The Dating Of Oestroid Divergences, Pierfilippo Cerretti, John O. Stireman Iii, Thomas Pape, James E. O'Hara, Marco A. Marinho, Knut Rognes, David A. Grimaldi

Biological Sciences Faculty Publications

Calyptrate flies include about 22,000 extant species currently classified into Hippoboscoidea (tsetse, louse, and bat flies), the muscoid grade (house flies and relatives) and the Oestroidea (blow flies, bot flies, flesh flies, and relatives). Calyptrates are abundant in nearly all terrestrial ecosystems, often playing key roles as decomposers, parasites, parasitoids, vectors of pathogens, and pollinators. For oestroids, the most diverse group within calyptrates, definitive fossils have been lacking. The first unambiguous fossil of Oestroidea is described based on a specimen discovered in amber from the Dominican Republic. The specimen was identified through digital dissection by CT scans, which provided morphological …

A New Tachinid Genus And Species Record For North America: Iceliopsis Borgmeieri Guimarães, John O. Stireman Iii, Jane E. Dell

Biological Sciences Faculty Publications

The Iceliini are a small, enigmatic New World tribe of Tachininae consisting of three genera, Icelia RobineauDesvoidy, Iceliopsis Guimarães, and Erviopsis Townsend, and five recognized species (Guimarães 1976). All known species are exclusively Neotropical in distribution with the exception of Icelia triquetra (Olivier), which ranges from Brazil, through Central America, and as far north as New York state (O’Hara & Wood 2004). Members of the tribe are generally medium-sized (ca. 7–12 mm), elongate, yellowish or grayish in color, and resemble Dexiini or Leskiini in general appearance. Species of Iceliini are relatively rarely collected and there is but a single host …

Vital Signs, Winter 2017, Boonshoft School Of Medicine

Vital Signs

A forty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth

Kno.e.sis Publications

Understanding the role of differential gene expression in cancer etiology and cellular process is a complex problem that continues to pose a challenge due to sheer number of genes and inter-related biological processes involved. In this paper, we employ an unsupervised topic model, Latent Dirichlet Allocation (LDA) to mitigate overfitting of high-dimensionality gene expression data and to facilitate understanding of the associated pathways. LDA has been recently applied for clustering and exploring genomic data but not for classification and prediction. Here, we proposed to use LDA inclustering as well as in classification of cancer and healthy tissues using lung cancer …

Genomic Vs. Non-Genomic Role Of The Ahr In Human Immunoglobulin Expression, Nasser Alhamdan

Browse all Theses and Dissertations

The immunoglobulin heavy chain gene (Igh) in various animal models is regulated by numerous regulatory elements including the 3'Igh regulatory region (3'IghRR). Several transcription factors are involved in modulating the 3'R including the aryl hydrocarbon receptor (AhR). The AhR is a ligand-activated transcription factor that mediates the transcription of genes involved in the metabolism of environmental toxicants such as TCDD. TCDD binds AhR and regulates immunoglobulin (Ig) expression in B cells. This modulation appears to be directly mediated by binding of the AhR to dioxin response elements (DRE) within the 3'IghRR. In human B cells, IgG secretion inhibited by TCDD …

Cx43 Expression Increases In Response To Increased Temperature Incubation In The Developing Chicken Embryonic Brain, Erick A. Barrios

Browse all Theses and Dissertations

We used the chicken embryo model to examine whether altered incubation temperature during chicken embryo development would alter the protein expression of heat shock protein 70 (hsp70), hsp90, and connexin 43 (cx43) in the brain. We incubated eggs in either optimal (37.6° C, Con), increased (39.6° C, +2), or decreased (35.6° C, -2) temperature conditions until they reached embryonic day 16 (E16). The -2 condition significantly increased incidence of embryonic mortality. As shown in the literature, the development of the eggs was accelerated or decelerated due to increased or decreased temperature respectively. To control for this, we incubated eggs at …

Erk3 As A Braf-Regulated Tumor Suppressor Is A New Potential Cancer Target In Melanoma, Minyi Chen

Browse all Theses and Dissertations

Melanoma is the highest mortality rate skin cancer and the sixth most common cancer in the U.S..[1, 2] Arising from melanocytes, melanoma is known for frequent mutation of BRAF to its constitutive activation state BRAFV600E, thus over-activating its downstream MAPK targets ERK1/2 and contributing to melanoma progression.[3, 4, 5] ERK3, a less studied MAPK family protein which contributes to promoting lung, breast, cervical, head and neck (HNC) cancer metastasis, has also shown a correlation with upregulation of BRAF.[6, 7, 8, 9] However, the BRAF-ERK3 regulatory mechanism and the function of ERK3 in melanoma are still unclear. Here, we first elucidate …