Digital Commons Network^™

Attitude Towards Gender Roles And Violence Against Women And Girls (Vawg): Baseline Findings From An Rct Of 1752 Youths In Pakistan, Tazeen S. Ali, Rozina Karmaliani, Judith Mcfarlane, Hussain M. A. Khuwaja, Yasmeen Somani, Esnat D. Chirwa, Rachel Jewkes

School of Nursing & Midwifery

Background: Violence against women is driven by gender norms that normalize and justify gender inequality and violence. Gender norms are substantially shaped during adolescence. Programs offered through schools offer an opportunity to influence gender attitudes toward gender equity if we understand these to be partly shaped by peers and the school environment.
Objective: We present an analysis of the baseline research conducted for a randomized controlled trial with 1752 grade 6 boys and girls and their attitudes toward gender roles, VAWG, and associated factors.
Methods: We used baseline data from a cluster randomised control study. Interviews were …

Exploring The Impact Of Gender Inequities On The Promotion Of Cardiovascular Health Of Women In Pakistan, Rubina Barolia, Alexander M. Clark, Gina M. Higginbottom

School of Nursing & Midwifery

Cardiovascular disease exerts an enormous burden on women's health. The intake of a healthy diet may reduce this burden. However, social norms and economic constraints are often factors that restrain women from paying attention to their diet. Underpinned by critical realism, this study explores how gender/sex influences decision-making regarding food consumption among women of low socioeconomic status (SES). The study was carried out at two cardiac facilities in Karachi, Pakistan, on 24 participants (male and female from different ethnic backgrounds), who had received health education. Using an interpretive descriptive approach, the study identified major barriers to a healthy diet: proscribed …

Studies On Antihyperlipidemic And Endothelium Modulatory Activities Of Polyherbal Formulation (Pol4) And Its Ingredients In High Fat Diet-Fed Rats, Abdul Malik, Malik H Mehmood, Muhammad S Akhtar, Anwar Gilani

Department of Biological & Biomedical Sciences

A compound herbal formulation (POL4) is used traditionally in interior parts (Distt. Badin) of Sindh, Pakistan, for the treatment of metabolic disorders like diabetes and hyperlipidemia. This study is aimed to determine the effectiveness of POL4 and its ingredients in hyperlipidemia and associated endothelial dysfunction and hypertension. POL4 is composed of equal proportion of Nigella sativa, Cichorium intybus, Trigonella foenum graecum and Gymnema sylvestre mixed in powdered form. Chronic (6 to 7 weeks) administration of POL4 and its ingredients mixed in diet caused a notable attenuation in total cholesterol, low density lipoprotein cholesterol, triglycerides, atherogenic index, C-reactive protein and glucose, …

Dialectics Of Imagination And Experimentation: Basic Science Research In Developing Countries, Hr Ahmad, Na Khan

Department of Biological & Biomedical Sciences

No abstract provided.

Engineered Peptides For Applications In Cancer-Targeted Drug Delivery And Tumor Detection, R. Soudy, N. Byeon, Y. Raghuwanshi, S. Ahmed, A. Lavasanifar, Kamaljit Kaur

Pharmacy Faculty Articles and Research

Cancer-targeting peptides as ligands for targeted delivery of anticancer drugs or drug carriers have the potential to significantly enhance the selectivity and the therapeutic benefit of current chemotherapeutic agents. Identification of tumor-specific biomarkers like integrins, aminopeptidase N, and epidermal growth factor receptor as well as the popularity of phage display techniques along with synthetic combinatorial methods used for peptide design and structure optimization have fueled the advancement and application of peptide ligands for targeted drug delivery and tumor detection in cancer treatment, detection and guided therapy. Although considerable preclinical data have shown remarkable success in the use of tumor targeting …

"Unorthodox Conduct": Re-Membering Queer Africa In Literature And Film, Matthew Patrick Durkin

Electronic Theses and Dissertations

"'Unorthodox Conduct'" explores positive representations of sexual and gender minorities in African literatures and film from the 1970s to 2010s that dismantle heterosexist notions of African sexuality and work towards what Ngũgĩ wa Thiong'o calls "re-membering." I interrogate how literary and cinematic depictions of same-sex sexualities resist contemporary homophobic attitudes, particularly those espoused by government and spiritual leaders. Positive literary and cinematic representations of queer Africans, however, have only emerged in recent years. These literary and cinematic representations are routinely minimized or ignored in academia as valid avenues for the navigation of interpersonal relationships and socio-political strife in queer African …

Techno-Salvation: Developing A Christian Hermeneutic Of Enhancement Technology, Richard Landrum Wilson

Electronic Theses and Dissertations

A cadre of scientists, philosophers, and ethicists labeled transhumanists and posthumanists argue that by strategic use of technology we can greatly enhance human beings into our next stage of evolution. Rather than leave the evolutionary process to natural results, transhumanists and posthumanists want to shape humanity to meet our own desires. This direct goal of changing human beings has profound implications for Christian faith and practices. At the same time, there is no reason to think that the utilization of technological enhancements will not happen. As such, to best meet the challenge, it is unavoidable for Christians to engage transhumanism …

Culture Counts: Examining The Effectiveness Of A Culturally Focused Empowerment Program For At-Risk Black Girls, Candice Nicole Aston

Electronic Theses and Dissertations

Traditionally, many of the problems experienced by Black girls were overshadowed by the ongoing crises facing Black Males. Although important, the focus on Blackness and masculinity often implicitly leaves young Black girls on the sidelines and fails to recognize their unique obstacles. Fortunately, there has been a new surge of social concern revolving around the plight of Black girls in the school system. New estimates report that Black girls are facing an educational crisis in regards to disproportionate discipline practices and academics (Morris, 2012). To date, there has been very limited research in regards to school-based interventions that have been …

Examining The Moderating Effects Of Racial Socialization On Teacher Discrimination For The Psychological Outcomes Of Black Middle School Girls, Kayla Nichols

Electronic Theses and Dissertations

A hierarchical multiple regression was used to understand the 1) the predictive ability of teacher discrimination on racial identity, 2) the predictive ability of teacher discrimination and racial identity on the educational beliefs and psychological outcomes of early adolescent Black girls, and 3) if egalitarian messages of racial socialization moderate the risk of teacher discrimination on the psychological outcomes for early adolescent Black girls. Participants were 8th grade Black girls from Wave 3 of the MADICS dataset (Eccles, 2010). Results showed that teacher discrimination had a negative relationship and predicted 5% of the variance in connection to heritage, educational beliefs, …

The Salvation Of The Cosmos: Benedict Xvi's Eschatology And Its Relevance For The Current Ecological Crisis, Jeremiah Vallery

Electronic Theses and Dissertations

Pope Emeritus Benedict XVI has elements of a cosmic eschatology embedded in his theological oeuvre that have not heretofore been extensively systematized. This dissertation fills this gap by contextualizing Benedict’s cosmic eschatology in the twentieth and twenty-first centuries, examining his Logos theology and his view on the fate of the cosmos, exploring his cosmic liturgy, and evaluating his concept of human ecology and pneumatology. Benedict insufficiently links his cosmic eschatology to his papal teachings on the environment; however, his cosmic eschatology can be developed in fruitful ways. After providing a thorough articulation of Benedict’s cosmic eschatology, I offer my own …

Burden Of Illness And Pharmacoeconomic Evaluation Of Lumacaftor/Ivacaftor In Cystic Fibrosis, Pratyusha Vadagam

Electronic Theses and Dissertations

Objectives: (1) To estimate the burden of illness in cystic fibrosis (CF) using 2010-2014 Medical Expenditure Panel Survey (MEPS) data, and (2) to conduct a pharmacoeconomic evaluation of lumacaftor/ivacaftor in the treatment of CF.

Methods: The study was conducted in two parts. Part 1 involved a retrospective analysis using individuals in MEPS database with an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis code of 277.00 for a principal diagnosis of CF. Dependent variables were cumulative and out-of-pocket (OOP) expenditures and independent variables included patient demographics and clinical characteristics. Unweighted and weighted estimates of expenditure in CF group, …

H. Wayne Huizenga College Of Business And Entrepreneurship 2017-2018 Graduate Catalog, Nova Southeastern University

Huizenga Postgraduate Course Catalogs

No abstract provided.

Northeastern Illinois University, Academic Catalog 2017-2018, Northeastern Illinois University

Course Catalogs

No abstract provided.

Differences Between The Genomes Of Lymphoblastoid Cell Lines And Blood-Derived Samples., Lena M Joesch-Cohen, Gustavo Glusman

Articles, Abstracts, and Reports

Lymphoblastoid cell lines (LCLs) represent a convenient research tool for expanding the amount of biologic material available from an individual. LCLs are commonly used as reference materials, most notably from the Genome in a Bottle Consortium. However, the question remains how faithfully LCL-derived genome assemblies represent the germline genome of the donor individual as compared to the genome assemblies derived from peripheral blood mononuclear cells. We present an in-depth comparison of a large collection of LCL- and peripheral blood mononuclear cell-derived genomes in terms of distributions of coverage and copy number alterations. We found significant differences in the depth of …

Early Mutation Bursts In Colorectal Tumors., Junsong Zhao, Matthew P Salomon, Darryl Shibata, Christina Curtis, Kimberly Siegmund, Paul Marjoram

Articles, Abstracts, and Reports

Tumor growth is an evolutionary process involving accumulation of mutations, copy number alterations, and cancer stem cell (CSC) division and differentiation. As direct observation of this process is impossible, inference regarding when mutations occur and how stem cells divide is difficult. However, this ancestral information is encoded within the tumor itself, in the form of intratumoral heterogeneity of the tumor cell genomes. Here we present a framework that allows simulation of these processes and estimation of mutation rates at the various stages of tumor development and CSC division patterns for single-gland sequencing data from colorectal tumors. We parameterize the mutation …

Astrocytes Promote Progression Of Breast Cancer Metastases To The Brain Via A Kiss1-Mediated Autophagy., Natalya Kaverina, Anton V Borovjagin, Zaira Kadagidze, Anatoly Baryshnikov, Maria Baryshnikova, Dmitry Malin, Dhimankrishhna Ghosh, Nameeta Shah, Danny R Welch, Patrik Gabikian, Apollon Karseladze, Charles Cobbs, Ilya V Ulasov

Articles, Abstracts, and Reports

Formation of metastases, also known as cancer dissemination, is an important stage of breast cancer (BrCa) development. KISS1 expression is associated with inhibition of metastases development. Recently we have demonstrated that BrCa metastases to the brain exhibit low levels of KISS1 expression at both mRNA and protein levels. By using multicolor immunofluorescence and coculture techniques here we show that normal adult astrocytes in the brain are capable of promoting metastatic transformation of circulating breast cancer cells localized to the brain through secretion of chemokine CXCL12. The latter was found in this study to downregulate KISS1 expression at the post-transcriptional level …

Persistence Of Low Disease Activity After Tumour Necrosis Factor Inhibitor (Tnfi) Discontinuation In Patients With Psoriatic Arthritis., D H Huynh, T A Boyd, C J Etzel, V Cox, J Kremer, P Mease, A Kavanaugh

Articles, Abstracts, and Reports

OBJECTIVE: To determine the duration of clinical benefit among patients with psoriatic arthritis (PsA) discontinuing tumour necrosis factor inhibitor (TNFi) therapy while in low disease activity (LDA), and to identify patient characteristics associated with prolonged clinical benefit.

METHODS: We performed an observational cohort study assessing patients with PsA from the Consortium of Rheumatology Researchers of North America (CORRONA) registry who had discontinued TNFi after achieving LDA, defined as clinical disease activity index (CDAI) score ≤10 and physician's global assessment (PGA) of skin psoriasis ≤20/100. Kaplan-Meier method was used to estimate the duration of clinical benefit.

RESULTS: Of the 5945 patients …

Chaotification As A Means Of Broadband Vibration Energy Harvesting With Piezoelectric Materials, Daniel Geiyer

Electronic Theses and Dissertations

Computing advances and component miniaturization in circuits coupled with stagnating battery technology have fueled growth in the development of high efficiency energy harvesters. Vibration-to-electricity energy harvesting techniques have been investigated extensively for use in sensors embedded in structures or in hard-to-reach locations like turbomachinery, surgical implants, and GPS animal trackers. Piezoelectric materials are commonly used in harvesters as they possess the ability to convert strain energy directly into electrical energy and can work concurrently as actuators for damping applications. The prototypical harvesting system places two piezoelectric patches on both sides of the location of maximum strain on a cantilever beam. …

The Study Of Physiochemical Properties Of Cerium Oxide Nanoparticles And Its Application In Biosensors, Swetha Barkam

Electronic Theses and Dissertations

Biosensors continue to get smaller and faster with the advancement in nanotechnology through the use of nanomaterials to achieve high sensitivity and selectivity. However, the continued reliance on biomolecules or enzymes in the biosensor assembly poses the problem of reproducibility, storage and complexity. This dissertation research address some of the challenges by investigating the physiochemical properties of nanoparticles to understand its interaction with biological systems and develop enzyme free biosensors. In this study, we have demonstrated a novel strategy to integrate cerium oxide nanoparticles (CNPs) as an efficient transducer through rigorous screening for developing enzyme/label free biosensors for detecting analytes …

Investigating Novel Water Treatment Methods And Monitoring Techniques For Sulfide-Laden Groundwater Supplies, Benjamin Yoakum

Electronic Theses and Dissertations

This dissertation reports on research related to novel water treatment and monitoring techniques for sulfide-laden groundwater supplies. The dissertation is divided into several chapters with four core chapters focused on investigations studying a novel water treatment method or monitoring technique. The first investigation assessed the efficacy of multi-pass spray aeration treatment to remove trihalomethanes (THMs) and to reduce the total THM formation potential (TTHMFP) of an aerated water column post-aeration. A recirculating spray aeration pilot unit was constructed to make this assessment. To assess the effect of multi-pass spray aeration on the TTHMFP, water was recirculated through a fabricated spray …

A Training Effectiveness Evaluation Of Uh-60a/L Simulated Environments: An Interdisciplinary Approach, Martin Goodwin

Electronic Theses and Dissertations

The U.S. military continues to develop and expand its use of simulation-based aviation training. While traditional simulation-based training continues to be a proven training method, game-based simulation has become more sophisticated and may provide viable training options in some applications. The use of game-based simulation with traditional simulation-based training can potentially reduce costs, enhance return on investment, advance training objectives, and inform future training environment designs. Current fiscal limitations are driving the need for more efficient training methods, while operational requirements are dictating training protocols that produce optimum levels of readiness. The gap between fiscal constraints and desired training outcomes …

Transposon-Mediated Stable Suppression Of Gene Expression In The Developing Chick Retina, Masaru Nakamoto, Chizu Nakamoto

Biology Faculty Publications

The embryonic chick has long been a favorite model system for in vivo studies of vertebrate development. However, a major technical limitation of the chick embryo has been the lack of efficient loss-of-function approaches for analyses of gene functions. Here, we describe a methodology in which a transgene encoding artificial microRNA sequences is introduced into embryonic chick retinal cells by in ovo electroporation and integrated into the genome using the Tol2 transposon system. We show that this methodology can induce potent and stable suppression of gene expression. This technique therefore provides a rapid and robust loss-of-function approach for studies of …

Routes For Infiltration, Tallgrass Prairie Center

Open Educational Resources

Students become a carbon atom and experience the movements of carbon through the environment, including its time sequestered in prairie roots.

Root Community, Tallgrass Prairie Center

Open Educational Resources

Pairs of students play a battleship-style game to show how roots explore the soil to obtain resources.

Educational Buildings As Educational Buildings: Can Sustainable Architecture Help Support Sustainability In The Curriculum?, Claire Speedie, Mark Mulville

Conference papers

This paper explores whether the architectural design of educational buildings - by incorporating an expression of the sustainable design - helps to educate users towards adoption of sustainable practices. Utilising observational studies from primary schools incorporating sustainable design measures, the research explored their impact on the curriculum.

School buildings accommodate the educational process but design briefs do not require that buildings educate their users. The paper demonstrated that sustainable features of the buildings were not well integrated into the curriculum and that one explanation was the lack of interpretation incorporated into the architecture to support teachers lacking an appreciation of …

A Pilot Study Into Bio-Behavioural Measurements On Air Traffic Controllers In Remote Tower Operations, Tanja Bos, Rolf Zon, Eszter Furedi, Dezso Dudas, Daniel Rohacs

H-Workload 2017: Models and Applications (Works in Progress)

What is the impact of shifting to remote tower operations on the Air Traffic Controller? In the joint HungaroControl-Netherlands Aerospace Centre NLR pilot project an assessment of bio-behaviour on three air traffic controllers was made in a remote tower and conventional tower. The research is motivated by HungaroControl’s plans in shifting to remote tower operations at Budapest airport in the upcoming years. This pilot project is considered a feasibility study to investigate if an eye tracker and a heart rate sensor can be used to derive workload, the controllers’ division of attention over information elements, and scanning strategies in two …

Model For Screened, Charge-Regulated Electrostatics Of An Eye Lens Protein: Bovine Gammab-Crystallin, Christopher W. Wahle, K. Michael Martini, Dawn M. Hollenbeck, Andreas Langner, David S. Ross, John F. Hamilton, George M. Thurston

Articles

We model screened, site-specific charge regulation of the eye lens protein bovine gammaB-crystallin (γB) and study the probability distributions of its proton occupancy patterns. Using a simplified dielectric model, we solve the linearized Poisson-Boltzmann equation to calculate a 54 × 54 work-of-charging matrix, each entry being the modeled voltage at a given titratable site, due to an elementary charge at another site. The matrix quantifies interactions within patches of sites, including γB charge pairs. We model intrinsic pK values that would occur hypothetically in the absence of other charges, with use of experimental data on the dependence of pK values …

Consciousness, Evidence, And Moral Standing, Irina Mikhalevich

Articles

Woodruff (2017) claims to have identified the neural correlates of phenomenal consciousness (“p-consciousness”) in fishes, and argues that these neurological data, along with behavioral evidence, suggest that teleost fishes are in all probability sentient organisms. Woodruff’s case may be strengthened by challenging key assumptions behind a common criticism of accounts such as his: that fishes cannot be p-conscious because they lack the cortical structures necessary for p-consciousness. A more serious objection to Woodruff’s proposal would be that his evidence for p-consciousness establishes only that fishes are “access-conscious” (“a-conscious”), where a-conscious states are cognitive representations that are made available to cognitive …

Surfing The Web With A Cave-Man Brain, Or Art Appreciation 40,000 Bce, W. Sumner Davis

Walden Faculty and Staff Publications

Methods: The study was conducted on individuals 20 years or older in the United States that live below the 130% Federal Poverty Level. We assessed food insecurity utilizing the Household Food Security Survey Module in NHANES survey between years 1999-2010 with mortality follow-up. Prospective analysis was performed using complex samples Cox regression with adjustment for known confounders to determine relationship of food insecurity on CRS.

Undergratuate Student Catalog 2017-2018, Nova Southeastern University

Undergraduate Programs Course Catalogs

No abstract provided.