Digital Commons Network^™

Climate Change In The Hudson River Estuary: Promoting Adaptation And Resilience Through Stakeholder Engagement In Design And Visualization, Gabrielle S.D. Weiss

Bard Center for Environmental Policy

In response to the growing risk to communities from climate change impacts, Professor Cerra at the Cornell University School of Landscape Architecture developed the Climate Adaptive Design (CAD) program. CAD is being implemented as a partnership between the Hudson River Estuary Program (Estuary Program) and Cornell that utilizes participatory design and visualization to engage communities about planning for future climate impacts. The goal of CAD is to build climate resilience, galvanize community participation and education, and build links to external sources of support including local institutions of higher education. This thesis outlines background for the development of the program and …

Public Perception Of Environmental Programs In The Sierra Gorda Biosphere Reserve, Landa De Matamoros, Queretaro, Mexico, Danielle Marie Salisbury

Bard Center for Environmental Policy

Biological or ecological corridors have recently been sought out as a solution to biodiversity loss due to habitat fragmentation. In eastern Mexico, the Mexican and German governments are collaborating to connect fragmented landscapes and Natural Protected Areas (NPAs) over five states across a Madrean Pine-Oak biodiversity hotspot through the implementation of the Ecological Corridor of the Sierra Madre Oriental (CESMO). One of the ways the CESMO is accomplishing its conservation goals is by extending environmental programs that are currently in place within NPAs to other areas within the corridor, but outside of NPA borders. However, the success of the corridor …

Addressing Antibiotic Resistance From Farm-Raised Fish Imported To The United States, Nicholas Ali

Bard Center for Environmental Policy

Misuse of medically important antibiotics in animal production threatens the effectiveness of drugs that are vital in combating disease and infections. Recently, the FDA implemented regulations to limit the use of and access to veterinary drugs. However, these regulations only affect domestic production operations. Because over 90% of seafood consumed in the U.S. is imported from countries with different regulatory standards and because the U.S. has an import inspection rate of less than 1%, antibiotic resistance stemming from imported aquaculture is still a risk that is not sufficiently accounted for. This research investigates how the U.S. has reacted to the …

Joan Delplato, Joan Delplato

Simon's Rock Institutional Oral History Project

Excerpts from the Oral History Project interview. The entire transcript and/or audio file may be restricted. For further access please contact the Simon's Rock College Archives.

• [I came to campus in] the spring of 1987, the year I got my doctoral dissertation finished and I came-- in April, I think it was, and my first impression was “oh my god… this place is so muddy.” [laughs] It was really-- it was full of mud, and I had been living in Los Angeles for eleven years and I didn’t have any boots, and I knew I was coming to a …

Wealth Poverty At Social Intersections: Differential Access And Accumulation, Daniella Medina Ms

Theses - Graduate Programs in Economic Theory and Policy

The Intersection of several axes of inequality characterize the nature of differential access to assets and debts and varying ability to accumulate wealth at quantifiably discernable “social locations.” In the United States, there exists sizeable gaps in wealth accumulation between single-headed male and female households, as well as between households of different racial/ethnic groups, but the application of Patricia Hill Collins’s Matrix of Domination to the economic analysis of inequality nuances measurable disparities by the intersection of race and gender. In a two-stage methodology using data from the 2010 and 2013 Survey of Consumer Finances (SCF), this thesis aims to …

Dollars And Drugs, Singapore Management University

Research@SMU: Connecting the Dots

Professor Locknie Hsu studies how trade deals affect the public’s access to affordable medicines and healthcare.

See her paper: Regulatory flexibilities and tensions in public health and trade: An Asian perspective; Tobacco control in ASEAN

See her book: Trade, investment, innovation and their impact on access to medicines: An Asian perspective

Ivan Illich’S Medical Nemesis And The ‘Age Of The Show’: On The Expropriation Of Death, Babette Babich

Articles and Chapters in Academic Book Collections

What Ivan Illich regarded in his Medical Nemesis as the ‘expropriation of health’ is exacerbated by the screens all around us, including our phones but also the patient monitors and increasingly the iPads that intervene between nurse and patient. To explore what Illich called the ‘age of the show’, this essay uses film examples, like Creed and the controversial documentary Vaxxed, and the television series Nurse Jackie. Rocky’s cancer in his last film (and his option to submit to chemo to ‘fight’ cancer) highlights what Illich along with Petr Skrabanek called the ‘expropriation of death’. In contrast to what Illich …

Taylor University Graduate Catalog 2017-18, Taylor University

Graduate Catalogs

The 2017-2018 graduate catalog of Taylor University in Upland, Indiana.

Taylor University Catalog 2017-2018, Taylor University

Undergraduate Catalogs

The 2017-2018 academic catalog of Taylor University in Upland, Indiana.

Innovative Education, President's Progress Report 2017, Ronald K. Machtley

Historical Documents of Bryant University (1863-present)

How can academic leadership create a culture of INNOVATION?

How can faculty more effectively convey their KNOWLEDGE?

How can students learn the skills, traits, and process to become future INNOVATORS?

Leadership Traits, Divergent Thinking, And Innovation In Higher Education, Barbara S. Marini

Master's Theses and Doctoral Dissertations

The topic of leadership is critical today as leaders’ decision-making processes affect political, social, and economic conditions globally. Considering market fluctuations and shifts, political uncertainty, environmental threats, and global societal issues, the question of leadership is at the heart of issues faced today as leaders impact people at all levels of society. The discussion regarding leadership has centered on the need for high-level critical and creative thinkers and has shifted towards academia as a source for innovation. Educational institutions are under a high level of scrutiny and pressure to prepare graduates effectively for a volatile and unpredictable global market, yet …

2017 Commencement Program, Seattle University

Commencement Programs

No abstract provided.

Identification Of Snps Associated With Muscle Yield And Quality Traits Using Allelic-Imbalance Analyses Of Pooled Rna-Seq Samples In Rainbow Trout, Rafet Al-Tobasei, Ali Ali, Timothy D. Leeds, Sixin Liu, Yniv Palti, Brett Kenney, Mohamed Salem

Faculty & Staff Scholarship

Coding/functional SNPs change the biological function of a gene and, therefore, could serve as “large-effect” genetic markers. In this study, we used two bioinformatics pipelines, GATK and SAMtools, for discovering coding/functional SNPs with allelic-imbalances associated with total body weight, muscle yield, muscle fat content, shear force, and whiteness. Phenotypic data were collected for approximately 500 fish, representing 98 families (5 fish/family), from a growth-selected line, and the muscle transcriptome was sequenced from 22 families with divergent phenotypes (4 low- versus 4 high-ranked families per trait).

Results

GATK detected 59,112 putative SNPs; of these SNPs, 4798 showed allelic imbalances (>2.0 …

Adopting The Citizen Suit Provision Of The United States Clean Water Act As A Tool For Water Pollution Enforcement In Turkey, Ozge Atil

Florida State University Journal of Transnational Law & Policy

No abstract provided.

Controlling The Error On Target Motion Through Real-Time Mesh Adaptation: Applications To Deep Brain Stimulation, Huu Phuoc Bui, Satyendra Tomar, Hadrien Courtecuisse, M. Audette, Stéphane Cotin, Stéphane P.A. Bordas

Computational Modeling & Simulation Engineering Faculty Publications

We present an error-controlled mesh refinement procedure for needle insertion simulation and apply it to the simulation of electrode implantation for deep brain stimulation, including brain shift.

Our approach enables to control the error in the computation of the displacement and stress fields around the needle tip and needle shaft by suitably refining the mesh, whilst maintaining a coarser mesh in other parts of the domain.

We demonstrate through academic and practical examples that our approach increases the accuracy of the displacement and stress fields around the needle without increasing the computational expense. This enables real-time simulations.

The proposed methodology …

"Insect Flight Has Garnered A Lot Of Attention From Both The Engineering And Biology Communities In The Recent Decades, Often Driven By An Interest In Bioinspired Or Bio-Mimicked Design Of Small Unmanned Aerial Vehicles, Called Micro-Air Vehicles (Mavs)...", Chang-Kwon Kang

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

New Approaches To Irrigation Scheduling Of Vegetables, Michael D. Cahn, Lee F. Johnson

School of Natural Sciences Faculty Publications and Presentations

Using evapotranspiration (ET) data for scheduling irrigations on vegetable farms is challenging due to imprecise crop coefficients, time consuming computations, and the need to simultaneously manage many fields. Meanwhile, the adoption of soil moisture monitoring in vegetables has historically been limited by sensor accuracy and cost, as well as labor required for installation, removal, and collection of readings. With recent improvements in sensor technology, public weather-station networks, satellite and aerial imaging, wireless communications, and cloud computing, many of the difficulties in using ET data and soil moisture sensors for irrigation scheduling of vegetables can now be addressed. Web and smartphone …

Human Liver Sinusoid On A Chip For Hepatitis B Virus Replication Study, Young Bok (Abraham) Kang, Siddhartha Rawat, Nicholas Duchemin, Michael Bouchard, Moses Noh

Faculty Publications - Biomedical, Mechanical, and Civil Engineering

We have developed a miniature human liver (liver-sinusoid-on-a-chip) model using a dual microchannel separated by a porous membrane. Primary human hepatocytes and immortalized bovine aortic endothelial cells were co-cultured on opposite sides of a microporous membrane in a dual microchannel with continuous perfusion. Primary human hepatocytes in this system retained their polygonal morphology for up to 26 days, while hepatocytes cultured in the absence of bovine aortic endothelial cells lost their morphology within a week. In order to demonstrate the utility of our human-liver-sinusoid-on-a-chip, human hepatocytes in this system were directly infected by Hepatitis B Virus (HBV). Expression of the …

Religion And The New Technologies, Noreen L. Herzfeld

School of Theology and Seminary Faculty Books

Noreen Herzfeld's featured article: https://doi.org/10.3390/books978-3-03842-531-1

Genetic Variation In Dip5, An Amino Acid Permease, And Pdr5, A Multiple Drug Transporter, Regulates Glyphosate Resistance In S. Cerevisiae, Xiaoqing Rong-Mullins, Apoorva Ravishankar, Kristen A. Mcneal, Zachery R. Longergan, Audrey C. Biega, J Philip Creamer, Jennifer E G Gallagher

Faculty & Staff Scholarship

S. cerevisiae from different environments are subject to a wide range of selective pressures, whether intentional or by happenstance. Chemicals classified by their application, such as herbicides, fungicides and antibiotics, can affect non-target organisms. First marketed as RoundUpTM, glyphosate is the most widely used herbicide. In plants, glyphosate inhibits EPSPS, of the shikimate pathway, which is present in many organisms but lacking in mam- mals. The shikimate pathway produces chorismate which is the precursor to all the aromatic amino acids, para-aminobenzoic acid, and Coenzyme Q10. Crops engineered to be resis- tant to glyphosate contain a homolog of EPSPS that is …

Herbivore Effects On Productivity Vary By Guild: Cattle Increase Mean Productivity While Wildlife Reduce Variability, Grace K. Charles, Lauren Mcgeoch Porensky, Corinna Riginos, Kari E. Veblen, Truman P. Young

Wildland Resources Faculty Publications

Wild herbivores and livestock share the majority of rangelands worldwide, yet few controlled experiments have addressed their individual, additive, and interactive impacts on ecosystem function. While ungulate herbivores generally reduce standing biomass, their effects on aboveground net primary production (ANPP) can vary by spatial and temporal context, intensity of herbivory, and herbivore identity and species richness. Some evidence indicates that moderate levels of herbivory can stimulate aboveground productivity, but few studies have explicitly tested the relationships among herbivore identity, grazing intensity, and ANPP. We used a long- term exclosure experiment to examine the effects of three groups of wild and …

College Catalog, 2017-2018, Buffalo State College

Academic Catalogs, 1871-2018

No abstract provided.

A Genome-Scale Model Of Shewanella Piezotolerans Simulates Mechanisms Of Metabolic Diversity And Energy Conservation, Keith Dufault-Thompson, Huahua Jian, Ruxue Cheng, Jiefu Li, Fengping Wang, Ying Zhang

Cell and Molecular Biology Faculty Publications

Shewanella piezotolerans strain WP3 belongs to the group 1 branch of the Shewanella genus and is a piezotolerant and psychrotolerant species isolated from the deep sea. In this study, a genome-scale model was constructed for WP3 using a combination of genome annotation, ortholog mapping, and physiological verification. The metabolic reconstruction contained 806 genes, 653 metabolites, and 922 reactions, including central metabolic functions that represented nonhomologous replacements between the group 1 and group 2 Shewanella species. Metabolic simulations with the WP3 model demonstrated consistency with existing knowledge about the physiology of the organism. A comparison of model simulations with experimental measurements …

Modulation Of The Fanconi Anemia Pathway Via Chemically Induced Changes In Chromatin Structure, David A. Vierra, Jada L. Garzon, Meghan A. Rego, Morganne M. Adroved, Maurizio Mauro, Niall G. Howlett

Cell and Molecular Biology Faculty Publications

Fanconi anemia (FA) is a rare disease characterized by congenital defects, bone marrow failure, and atypically early-onset cancers. The FA proteins function cooperatively to repair DNA interstrand crosslinks. A major step in the activation of the pathway is the monoubiquitination of the FANCD2 and FANCI proteins, and their recruitment to chromatin-associated nuclear foci. The regulation and function of FANCD2 and FANCI, however, is poorly understood. In addition, how chromatin state impacts pathway activation is also unknown. In this study, we have examined the influence of chromatin state on the activation of the FA pathway. We describe potent activation of FANCD2 …

Defining Genetic Fitness Determinants And Creating Genomic Resources For An Oral Pathogen, Ajay M. Narayanan, Matthew M. Ramsey, Apollo Stacy, Marvin Whiteley

Cell and Molecular Biology Faculty Publications

Periodontitis is a microbial infection that destroys the structures that support the teeth. Although it is typically a chronic condition, rapidly progressing, aggressive forms are associated with the oral pathogen Aggregatibacter actinomycetemcomitans. One of this bacterium's key virulence traits is its ability to attach to surfaces and form robust biofilms that resist killing by the host and antibiotics. Though much has been learned about A. actinomycetemcomitans since its initial discovery, we lack insight into a fundamental aspect of its basic biology, as we do not know the full set of genes that it requires for viability (the essential genome). Furthermore, …

Comparative Genomic Analysis Of The Class Epsilonproteobacteria And Proposed Reclassification To Epsilonbacteraeota (Phyl. Nov.), David W. Waite, Inka Vanwonterghem, Christian Rinke, Donovan H. Parks, Ying Zhang, Ken Takai, Stefan M. Sievert, Jörg Simon, Barbara J. Campbell, Thomas E. Hanson, Tanja Woyke, Martin G. Klotz, Philip Hugenholtz

Cell and Molecular Biology Faculty Publications

The Epsilonproteobacteria is the fifth validly described class of the phylum Proteobacteria, known primarily for clinical relevance and for chemolithotrophy in various terrestrial and marine environments, including deep-sea hydrothermal vents. As 16S rRNA gene repositories have expanded and protein marker analysis become more common, the phylogenetic placement of this class has become less certain. A number of recent analyses of the bacterial tree of life using both 16S rRNA and concatenated marker gene analyses have failed to recover the Epsilonproteobacteria as monophyletic with all other classes of Proteobacteria. In order to address this issue, we investigated the phylogenetic placement of …

Dengue Virus Induces Mitochondrial Elongation Through Impairment Of Drp1-Triggered Mitochondrial Fission, Vincent Barbier, Diane Lang, Dierra Valois, Alan L. Rothman, Carey L. Medin

Cell and Molecular Biology Faculty Publications

Mitochondria are highly dynamic organelles that undergo continuous cycles of fission and fusion to maintain essential cellular functions. An imbalance between these two processes can result in many pathophysiological outcomes. Dengue virus (DENV) interacts with cellular organelles, including mitochondria, to successfully replicate in cells. This study used live-cell imaging and found an increase in mitochondrial length and respiration during DENV infection. The level of mitochondrial fission protein, Dynamin-related protein 1 (Drp1), was decreased on mitochondria during DENV infection, as well as Drp1 phosphorylated on serine 616, which is important for mitochondrial fission. DENV proteins NS4b and NS3 were also associated …

Antimicrobial Resistance (Amr) And Multidrug Resistance (Mdr): Overview Of Current Approaches, Consortia And Intellectual Property Issues, Andrew Jenner, Niresh Bhagwandin, Stanley P. Kowalski

Law Faculty Scholarship

The supply of new diagnostics and treatments is insufficient to keep up with the increase in antimicrobial resistance (AMR) and multidrug resistance (MDR) as older medicines are used more widely and microbes develop resistance to them. At the same time, significant quantities of antibiotics are used on patients and animals that do not need them, while others who do need them lack access.

Effective responses to AMR/MDR require effort by both the public and private sectors to develop and disseminate new diagnostics, vaccines and treatments on a global scale, as well as to adapt them to local needs. This calls …

Marriage On Our Own Terms, Teri Dobbins Baxter

Scholarly Works

No abstract provided.

Pathophysiological Relevance Of Astroglial Angiotensin And The Endocannabinoid Signaling Systems In Shrs, Dhanush Haspula

Student Theses, Dissertations and Capstones

BACKGROUND: Spontaneously hypertensive rats (SHRs), an essential hypertension model, are characterized by pro-inflammatory states in brainstems. While Angiotensin (Ang) II, via activation of glial Ang Type 1 receptors (AT1Rs), has been shown to trigger a significant upsurge in pro-inflammatory cytokines, activation of astroglial Cannabinoid Type 1 Receptors (CB1Rs), elicits a potent anti-inflammatory response in the brain. Both brainstem AT1Rs and CB1Rs have also been reported to alter cardiovascular parameters in SHRs. Evidence of crosstalk between CB1Rs and AT1Rs has also emerged, further highlighting a need to understand their signaling interaction in cardiovascular diseases. APPROACH: The purpose of this study was …