Digital Commons Network^™

How Existing Environmental Laws Respond To Climate Change And Its Mitigation, Justin Gundlach

Sabin Center for Climate Change Law

Existing environmental laws interact with public health priorities and with aspects of the changing climate in numerous and varied ways. This chapter does not attempt to catalogue those interactions, but instead focuses on two that are especially important and illustrative of the operation and limitations of existing environmental laws vis-à-vis climate change-driven challenges. The first interaction is between pollution levels boosted by climate change and pollution control laws that employ health-based standards to determine pollution limits. The second is between a wider array of existing laws and the effects of climate change mitigation measures on public health. Examining these interactions …

Anthelmintic Efficacy Of Bioactive Compounds Within Cranberry Vine And Birdsfoot Trefoil, Carly Barone

Open Access Dissertations

With the growth of resistance to commercial dewormers in small ruminant gastrointestinal nematodes (GIN), alternative methods are needed for GIN control. It has been shown that plants containing certain secondary compounds (SC) suppress GIN infection, but there is a lack of knowledge concerning the mechanism behind this anthelmintic activity, as well as a lack of viable alternatives to commercial dewormers in the northeastern United States. Secondary compounds, such as proanthocyanidin (PAC), have complex chemical structures that vary between plant species, while SC concentrations can vary between different varieties of the same species. The relationship between specific SC and anti-parasitic efficacy …

Exploring Ways To Enhance Teens' Participation In Social Media Interventions: A Formative Research Study, Hailee K. Dunn

Open Access Dissertations

Social networking sites (SNSs) now serve as a primary form of socialization for adolescents. A growing body of research indicates that permissive drinking norms exist on online just as they do offline increasing teens’ risk for underage drinking and other risk behaviors. However, limited research exists on how to address this growing public health problem. The purpose of the present study was to conduct a formative investigation on how to create substance prevention interventions that address adolescents’ exposure to normative displays of substance use on SNSs. Thirty-three adolescents in grades nine through twelve were recruited from various school- and community-based …

Alcohol Use And Immune Reconstitution Among Hiv-Infected Patients On Antiretroviral Therapy In Nairobi, Kenya, Anthony Cagle, Christine Mcgrath, Barbra A. Richardson, Dennis Donovan, Sameh Sakr, Nelly Yatich, Richard Ngomoa, Agnes Chepngeno Langat, Grace John-Stewart, Michael Chung

Internal Medicine, East Africa

Studies on the effects of alcohol use on HIV disease progression have been contradictory, with at least one study finding a positive effect of low alcohol consumption on CD4 count. In addition, most such studies have taken place in the developed West. We investigated the association between alcohol use and immune reconstitution through CD4 count response among HIV-infected individuals on antiretroviral therapy (ART) at an urban sub-Saharan African clinic. This was a retrospective cohort study of treatment-naïve HIV-infected adults initiating ART in Nairobi, Kenya and followed for 12 months between January 2009 and December 2012. At enrollment, a standardized questionnaire …

Transitions Of Social-Ecological Subsistence Systems In The Arctic, Per Fauchald, Vera Hausner, Jennifer Schmidt, Douglas A. Clark

ISER Articles

Transitions of social-ecological systems (SES) expose governance systems to new challenges. This is particularly so in the Arctic where resource systems are increasingly subjected to global warming, industrial development and globalization which subsequently alter the local SES dynamics. Based on common-pool resource theory, we developed a dynamic conceptual model explaining how exogenous drivers might alter a traditional subsistence system from a provisioning to an appropriation actions situation. In a provisioning action situation the resource users do not control the resource level but adapt to the fluctuating availability of resources, and the collective challenge revolve around securing the subsistence in the …

N-Acetyl-D-Glucosamine-Reactive Natural Antibodies: Roles In Suppression Of Autoimmune Diabetes And Environmental Factors Influencing Their Development, James Stewart New

All ETDs from UAB

Type 1 Diabetes suppression in diabetes prone mice following immunization with Group A Streptococcus correlates with the B lymphocyte response to N-acetyl-D-glucosamine (GlcNAc) present in the Group A Carbohydrate cell wall polysaccharide. GlcNAc-specific B cells recognize cryptic GlcNAc-epitopes in beta cells. Following exposure of GlcNAc-modified antigens on beta cells during cellular apoptosis, GlcNAc-specific IgM antibodies opsonize these epitopes and mediate classical complement pathway activation. In vitro, opsonization of apoptotic beta cells with GlcNAc-specific IgM increases their uptake by dendritic cells, while suppressing the subsequent presentation of beta cell-derived antigens to diabetogenic T lymphocytes. Passive administration of Group A Streptococcus antisera …

Associations Of Food Environment, Mediterranean Diet And Obesity In United States: A Geographic Information System (Gis) Analysis, Meifang Chen

All ETDs from UAB

Given the growing obesity epidemic in the U.S., modifying current obesogenic food environment, and identifying and promoting an obesity-modifying dietary approach that fits in the food environment context are urgent. Emerging evidence indicates that Mediterranean diet (MD) could be a beneficial dietary pattern to protect against overweight/obesity. However, as a relatively new dietary pattern in the U.S., how the unique food environment influences MD adherence, and whether consuming a MD can mediate the relationship between food environment and obesity among the population remain unknown. This dissertation, applying Geographic Information System (GIS) and path analytical methods using data from the REasons …

Relationship Between Walking Speed And Kinematic Trajectory Complexity In People With Poststroke Hemiparesis, Deanna Delayne Rumble

All ETDs from UAB

Individuals with chronic poststroke hemiparesis (PS) exhibit increased variability in spatiotemporal kinematic variables related to endpoint control during walking. For nonimpaired individuals, walking faster or slower than a preferred walking speed, results in less consistent stepping behavior. In three studies I investigated variability in swing phase foot trajectory area on a step-by-step basis (SBS-FTA) in nonimpaired individuals and people with PS. The primary aims of these studies were to 1) validate SBS-FTA in nonimpaired individuals, 2) observe if there was a difference in SBS-FTA variability between nonimpaired individual’s limb, the PS paretic, and nonparetic limbs, and across a wide range …

Development Of Scenarios For Land Cover, Population Density, Impervious Cover, And Conservation In New Hampshire, 2010–2100, Alexandra M. Thorn, Cameron P. Wake, Curt D. Grimm, Clayton R. Mitchell, Madeleine M. Mineau, Scott V. Ollinger

Faculty Publications

Future changes in ecosystem services will depend heavily on changes in land cover and land use, which, in turn, are shaped by human activities. Given the challenges of predicting long-term changes in human behaviors and activities, scenarios provide a framework for simulating the long-term consequences of land-cover change on ecosystem function. As input for process-based models of terrestrial and aquatic ecosystem function, we developed scenarios for land cover, population density, and impervious cover for the state of New Hampshire for 2020–2100. Key drivers of change were identified through information gathered from six sources: historical trends, existing plans relating to New …

Phenotypic Characteristics And Dietary Treatment Of Pediatric Non-Alcoholic Fatty Liver Disease, Shima Dowla

All ETDs from UAB

Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder among children in the developed world and can progress to cirrhosis, hepatocellular carcinoma, and liver failure. Objectives: The primary objectives of this dissertation were to (1) review advances in the field of pediatric NAFLD, (2) describe the demographic, anthropometric and metabolic characteristics of children with NAFLD and evaluate whether differences existed based on ethnicity and diagnostic method, and (3) compare the effect of a carbohydrate restricted diet vs fat reduced diet on improvement in hepatic steatosis over an 8-week period among overweight and obese children diagnosed with NAFLD. …

Purification, Characterization, And Enzymatic Activity Of Human Cytosolic Sulfotransferase 1c4, Amber Lynn Guidry

All ETDs from UAB

Human cytosolic sulfotransferase 1C4 (hSULT1C4) is a dimeric Phase II drug-metabolizing enzyme primarily expressed in the developing fetus. SULTs facilitate the transfer of a hydrophilic sulfonate moiety from 3’-phosphoadenosine-5’-phosphosulfate (PAPS) onto an acceptor substrate altering the substrate’s biological activity and increasing the compound’s water solubility. While several of the hSULTs’ endogenous and xenobiotic substrates have been identified, the physiological function of hSULT1C4 remains unknown. The fetal expression of hSULT1C4 leads to the hypothesis that the function of this enzyme may be to regulate metabolic and hormonal signaling molecules, such as estrogenic compounds, that may be generated or consumed by the …

Play With Power: A City Park Along The Trinity River, Xiwei Shen

Honors Capstones

No abstract provided.

Advances In The Creation And Use Of Genetically Modified Rodent Models, Laura Lambert

All ETDs from UAB

Rodents have been the model of choice for decades in biomedical research due to their relatively high physiological similarity to humans and amenability to genomic modification. While transgenic constructs were first used in mouse blastocysts in 1974 and the first mouse embryonic stem (ES) cell line created in 1981, the lack of reliable methods to produce ES cells or culture embryos from the rat led to the limitation of its use in spite of several advantages such as larger size and higher genetic homology with humans. Use of genetic modification has recently expanded due to the advent of tailored nucleases …

Cancer-Related Symptoms And Cognitive Intervention Adherence Among Breast Cancer Survivors: A Mixed Methods Study, Jennifer Bail

All ETDs from UAB

Advancements in screening, early detection, and treatment have increased breast cancer survival. In the United States, the 5-year relative survival rate for breast cancer is 89%. With more women surviving breast cancer, there are now more than 3.5 million breast cancer survivors (BCS), a figure estimated to increase to 4.3 million by 2020. Survivors experience long-term symptoms of their cancer and treatment which may last years and even decades after diagnosis and treatment. This symptom experience may potentially have exacerbating effects on BCS’ cognitive function as well as their ability to adhere to interventions aimed at improving cognitive function. The …

Exploring Psychosocial And Situational Factors That Influence Female College Students' Participation In Oral Sex, Margaret Bergeron

All ETDs from UAB

Although sexually transmitted infections (STI) are not officially reported via the route of transmission, the CDC (2016) reports that individuals who provide fellatio have the highest risk of oral transmission of a STI. Therefore, females who engage in fellatio are at risk for acquiring a STI. The majority of research studies on young adult heterosexual female sexual activities primarily focus on vaginal sex and the associated risks of pregnancy and sexually transmitted infections. Limited research exists on the oral sex behaviors of female college students and their understanding of the risk for contracting an STI through fellatio. The purpose of …

Hospital Purchasing Alliance: Contextual Factors And Financial Performance, William Opoku-Agyeman Opoku-Agyeman

All ETDs from UAB

Collectively, the purpose of the three papers included in this dissertation was to provide empirical evidence on the contextual factors that influence hospital utilization of services of group purchasing organizations and how utilization of group purchasing organizations impacts hospitals’ financial performance. The findings of these studies are important both to researchers and to managers as it sheds light on the relationship between hospitals and group purchasing organizations. The results of this dissertation suggest that better financial performance is associated with hospital utilization of group purchasing organizations. Additionally, some measures of environmental munificence and dynamism are associated with hospital utilization of …

The Dietary Context Of Nut Intake Among Overweight And Obese African-American Women Living In The Rural South: An Exploratory Study, Samara Sterling

All ETDs from UAB

Obesity has become a national epidemic over the last few decades, and lays its heaviest burden on certain populations (eg, rural residents, African-Americans, and African-American women in the Southeast). Obesity increases medical costs substantially, and is a significant risk factor for various chronic conditions, including certain cancers. There is a need to identify specific dietary behaviors that may contribute to obesity and obesity-related cancers among African-American women in the rural South, and to recommend dietary modifications that may alleviate those risks. Previous research has shown that nuts offer numerous health benefits, including weight loss and cancer protection. More research is …

A Coupled Terrestrial And Aquatic Biogeophysical Model Of The Upper Merrimack River Watershed, New Hampshire, To Inform Ecosystem Services Evaluation And Management Under Climate And Land-Cover Change, Nihar R. Samal, Wilfred M. Wollheim, Shantar Zuidema, Robert J. Stewart, Zaixing Zhou, Madeleine M. Mineau, Mark E. Borsuk, Kevin H. Gardner, Stanley J. Glidden, Tao Huang, David A. Lutz, Georgia Mayrommati, Alexandra M. Thorn, Cameron P. Wake, Matthew Huber

Faculty Publications

Accurate quantification of ecosystem services (ES) at regional scales is increasingly important for making informed decisions in the face of environmental change. We linked terrestrial and aquatic ecosystem process models to simulate the spatial and temporal distribution of hydrological and water quality characteristics related to ecosystem services. The linked model integrates two existing models (a forest ecosystem model and a river network model) to establish consistent responses to changing drivers across climate, terrestrial, and aquatic domains. The linked model is spatially distributed, accounts for terrestrial–aquatic and upstream–downstream linkages, and operates on a daily time-step, all characteristics needed to understand regional …

Assessing The Efficiency Of Different Sustainable Farming Practices In Reducing The Environmental Impacts Caused By Aquaculture, Rajee Olaganathan, Alicia Tang Kar Mun

Publications

Sustainability of aquaculture is achieved when aquaculture farming systems are capable of preserving the natural resource base and involves an institutional change to the environment by the attainment and continued satisfaction for present and future generations. Sustainable farming practices produce sufficient aquaculture output to satisfy the seafood demand while not burdening the environment more. The potentiality and efficiency of different sustainable aqua farming practices in reducing anthropogenic impacts to the environment by aquaculture are assessed in this paper. Polyculture is mostly adopted by small-scale rural farmers as it requires low entry barrier and help in income diversification. The input of …

Barring Survivors Of Domestic Violence From Food Security: The Unintended Consequences Of 1996 Welfare And Immigration Reform, Claire R. Thomas, Ernie Collette

Articles & Chapters

During the 1990s, Congress amended the Immigration and Nationality Act (“INA”) to create forms of immigration relief for previously neglected vulnerable groups. One such group—survivors of domestic violence—was aided through the Violence Against Women Act (“VAWA”), which amended the INA to allow abused spouses, children, and parents of U.S. citizens or lawful permanent residents to self-petition for family-based immigration benefits without the abuser’s knowledge. Both abused female and male spouses are able to receive immigration benefits under VAWA, as well as spouses in same-sex marriages.

Despite protections in immigration law for survivors of domestic violence, two other acts—the Personal Responsibility …

Cultural Identity And Cuisine In Taiwan, Cassidy A. Pfau

University Honors Theses

This paper explores the relationship between food, culture, and national identity in the Taiwanese context. Beginning with a review of relevant Taiwanese history, this paper then shifts into a theoretical discussion on the topics of hybridity, globalization, identity formation, and how cuisine impacts cultural and national identity. In order to understand how these theories operate in Taiwan, a discussion of three topics is then presented: Aboriginal culture and cuisine, Japanese colonial history and its impact on Taiwanese identity, and Taiwanese-specialty foods as a symbol of national identity. Taiwan has created a unique cultural heritage using cuisine (among other cultural elements), …

The Transcriptome Response Of The White-Rot Fungus Phanerochaete Chrysosporium To Maple And Miscanthus, Mashael Rashed Alaradi

Masters Theses

Lignocellulosic biomass is a valuable feedstock for the production of liquid biofuels. However, liquid biofuel production from lignocellulose is economically challenging due to the difficulties associated with separating the cellulosic sugars from lignin. In addition, the current thermochemical methods to deconstruct lignocellulose typically involve hazardous chemicals that can negatively impact the environment. Recent studies have demonstrated the efficacy of white-rot fungi as alternative pretreatment agents that can lower the costs of lignocellulose deconstruction and reduce negative impacts on the environment. However, understanding of the biochemical mechanisms of lignocellulose breakdown used by these fungi is limited, particularly with respect to the …

Perceived Body Image In Female Athletes By Sport Uniform Type, Mary Elizabeth Gillespie

Masters Theses

The purpose of this study was to investigate whether collegiate sport teams in which female participants are required to wear uniforms that are more revealing, have a more negative self-perception of body image and greater drive for muscularity than those with non-revealing uniforms. Female athletes from 7 women's NCAA Division I collegiate athletic teams from a Midwestern university took part in this study. Subjects were grouped according to the type of uniform worn during competition in their sport. Subjects were divided into two categories: revealing uniforms (n = 33), which included volleyball, track and field, cross country, and swimming, while …

Thinking And Acting Both Globally And Locally : The Field School In Intercultural Education As A Model For Action-Research Training And Civic Learning., Douglas D. Perkins, Benjamin W. Fisher, Holly L. Karakos, Sharon L. Shields, Elizabeth D. Gilbert, Meaghan M. Patterson

Faculty and Staff Scholarship

We present the Field School model of intercultural civic education, service-learning, action research training, and collaboration (with local academic and community partners) based on field work in applied anthropology. Theoretical and methodological foundations of the Field School also include experiential learning and immersive pedagogy, multiculturalism and cross-cultural communication, international education and study abroad programs, collaborative international development, participatory research, and in-depth knowledge in one’s own specific discipline. The primary goals of these intensive, short-term action research projects in other, less-developed countries or regions are benefits for community partners that are as sustainable as possible and to foster and assess learning …

Efficacy Of Collaborative Consulting Training Module, Brenda Stone

Theses and Dissertations

Code for America Fellowships pair technologists with local city governments to develop digital tools that support how governments provide service to their communities. The lack of project sustainability following these Fellowships has been a source of dissatisfaction for both Fellows and clients. Code for America supports each Fellow with technical training, but provides no training on consulting techniques that help clients sustain the changes or new technology being introduced. The purpose of this action research study was to determine the efficacy of a collaborative consultation module for the Fellows at Code for America. To gather data, surveys, interviews and analysis …

On Solid Ground I Stand: Narratives On Disclosure, Resilience, And Faith Amidst Recognition Of Childhood Sexual Abuse, Wade Rhodes Dundee

Masters Theses

Childhood sexual abuse seems to be a hidden secret in American society; one of the famous, "If we don't talk about it, it won't happen" narratives. However, we know this is not true. Both the National Sexual Violence Resource Center (2012) and Center for Disease Control and Prevention (2005) state one in four girls and one in six boys will fall victim to sexual abuse before they celebrate their 18th birthday. There is a high probability that because of the alarming lack of disclosure of male survivors, these statistics could be incorrect and could hinder creating or allowing for conversations …

Natural Resources, Institutions, And Poverty: The Case Of The Mena Region, Abdulrhman M. Alamoudi

Masters Theses

While several Middle East and North Africa countries have a huge endowment of natural resources such as oil and natural gas, poverty indicators, as expressed by well-being indicators and headcount, are no better in these countries than others that are relatively poor in natural resources. For instance, oil rich countries, such as Syria and Sudan, have a lower life expectancy and school enrollment than poor-resources countries like Lebanon and Israel. This study thereby, investigates the cross-country differences of poverty response to changes in natural resources wealth. The paper utilizes a panel data model for the period from 1985 to 2014 …

Issues In Christian Encounters With Yoga: Exploring 3ho/Kundalini Yoga, Michael Stoeber

Journal of Hindu-Christian Studies

The paper begins by drawing out current issues that have been raised by critics concerning the contemporary practice of Hindu postural types of yoga in western and specifically western Christian contexts, with some illustrative reference to contemporary movements and schools, especially to Bikram Yoga. These are: cultural misappropriation; commodification; lack of moral pre-requisites; narcissistic attachment to bodily effects; occult influences; and doctrinal differences. The paper then explores specific aspects of the theory and practice of 3HO/Kundalini Yoga (3HO/KY) by Christians in light of these possible issues, showing how this tradition of Kundalini Yoga seems to skirt or side-step most of …

Discovery And Characterization Of Novel Antimicrobials Against Mycobacterium Tuberculosis, Carolina Rodrigues Felix

Electronic Theses and Dissertations

Tuberculosis disease is currently a global health emergency, causing the most deaths worldwide due a single infectious agent. Eradication of TB is hampered by lack of an effective vaccine and poor treatment options. During infection, host-derived cues such as hypoxia and starvation induce Mycobacterium tuberculosis to halt replication and become dormant, which leads to tolerance to front-line antibiotics used in the TB treatment. This dormant phenotype causes delayed clearance of M. tuberculosis, therefore a long treatment time is required for stable cure without relapse. Poor patient compliance increases the emergence of drug resistant strains, posing yet another challenge for the …

Intrinsic Factors Affecting Decomposition Changes In Archaeological Head Hair From Kellis 2 Cemetery, Dakhleh Oasis, Egypt, Kathleen Cole

Electronic Theses and Dissertations

Post-mortem hair root degradation, and associated characteristics such as post-mortem root banding, brush-like ends, and hard keratin points, has remained a little understood phenomenon in the forensics discipline since its discovery in the 1800's. At present, the underlying causes of these characteristics are still unknown. In addition, there is no standardization for preparing samples for forensic or archaeological analysis. In this study, 1200 hairs from a total of 51 individuals (males, n = 22; females, n = 29) ranging in age from 16 to 60+ and interred at the Kellis 2 cemetery in the Dakhleh Oasis, Egypt are examined microscopically …