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Growth And Doping Of Mos2 Thin Films For Electronic And Optoelectronic Applications, Hussain Abouelkhair

Electronic Theses and Dissertations

MoS2 high absorption coefficient, high mobility, mechanical flexibility, and chemical inertness is very promising for many electronic and optoelectronic applications. The growth of high-quality MoS2 by a scalable and doping compatible method is still lacking. Therefore, the suitable dopants for MoS2 are not fully explored yet. This dissertation consists mainly of four main studies. The first study is on the growth of MoS2 thin films by atmospheric pressure chemical vapor deposition. Scanning electron microscope images revealed the growth of microdomes of MoS2 on top of a smooth MoS2 film. These microdomes are very promising as a broadband omnidirectional light trap …

Faculty Knowledge And Readiness In Reporting Student Victimization Disclosure And Title Ix Compliance, Abigail Malick

Electronic Theses and Dissertations

The U.S. Department of Education and Title IX Educational Act of 1972 shaped the way institutions of higher education address and prevent student victimizations. The law originally sought to eliminate sex-based discrimination in education but has evolved to include sexual misconduct. Since the Dear Colleague Letter of 2011, the position of institutions has changed significantly in the way they address student victimization as it relates to dating violence, sexual assault, and stalking (Rosenthal, 2017). One requirement is that institutions inform and train Responsible Employees to report when a student discloses experiencing sexual misconduct, including dating violence, sexual assault, or stalking. …

Development Of Molecular Diagnostic Tools For Mycobacterium Species, Hillary Bengtson

Electronic Theses and Dissertations

This dissertation focuses on the development of diagnostic tools for mycobacteria using hybridization based technologies including binary deoxyribozyme (BiDz) sensors and microarrays. The genus Mycobacterium, is a diverse group of bacteria containing 150+ species including M. tuberculosis (M.tb) and non-tuberculous mycobacteria (NTM) which exhibit a range of pathogenicity, drug susceptibility and growth characteristics. M. tuberculosis (M.tb) is the causative agent of tuberculosis (TB) and the leading cause of infectious disease related deaths worldwide. The control of TB is limited by the lack of sensitive and specific diagnostic tools available at the point of care (POC). The studies presented here illustrate …

Targeted Therapy Development For Neurofibromatosis Type 2, Marisa Fuse

Electronic Theses and Dissertations

Neurofibromatosis type 2 (NF2) is a debilitating disease characterized by the formation of bilateral vestibular schwannomas, which compress the vestibulocochlear nerve and cause deafness. Additional peripheral schwannomas, meningiomas and ependymomas may also form. NF2 is caused by mutations in the NF2 gene, resulting in the loss of function of the merlin tumor suppressor. Merlin functions in multiple signaling pathways and its absence in Schwann cells yields increased cell survival and proliferation, thereby causing schwannoma formation. First line treatment for NF2 is watchful waiting and surgical removal of tumors, potentially resulting in facial paralysis and deafness. To date, there are no …

Novel Photonic Resonance Arrangements Using Non-Hermitian Exceptional Points, Hossein Hodaei

Electronic Theses and Dissertations

In recent years, non-Hermitian degeneracies also known as exceptional points (EPs) have emerged as a new paradigm for engineering the response of optical systems. EPs can appear in a wide class of open non-Hermitian configurations. Among different types of non-conservative photonic systems, parity-time (PT) symmetric arrangements are of particular interest since they provide an excellent platform to explore the physics of exceptional points. In this work, the intriguing properties of exceptional points are utilized to address two of the long standing challenges in the field of integrated photonics- enforcing single mode lasing in intrinsically multimode cavities and enhancing the sensitivity …

Inside The Arbitrator's Mind, Chris Guthrie, Susan D. Franck, Anne Van Aaken, James Freda, Jeffrey J. Rachlinski

Vanderbilt Law School Faculty Publications

Arbitrators are lead actors in global dispute resolution. They are to global dispute resolution what judges are to domestic dispute resolution. Despite its global significance, arbitral decision making is a black box. This Article is the first to use original experimental research to explore how international arbitrators decide cases. We find that arbitrators often make intuitive and impressionistic decisions, rather than fully deliberative decisions. We also find evidence that casts doubt on the conventional wisdom that arbitrators render “split the baby” decisions. Although direct comparisons are difficult, we find that arbitrators generally perform at least as well as, but never …

Dignity Takings, Dignity Restoration: A Tort Law Perspective, Valerie P. Hans

Cornell Law Faculty Publications

Money damages can operate to restore the dignity of a person who has been injured in tort or deprived of property. A financial award or settlement conveys an acknowledgment of the wrong and signals the reestablishment of equity between defendant and plaintiff. Whether the award is seen as adequate to fully restore dignity is influenced by context, especially comparison cases. And financial compensation directly provided by the defendant holds greater promise for dignity restoration.

Restoring Liberalism To Transnational Corporate Accountability: From Universal Jurisdiction's Ashes To An Afterlife Of Multilateral Avenues, Steven S. Nam

Emory International Law Review

Per the U.S. Supreme Court, foreign tortfeasors, including corporate human rights violators, may no longer be sued in U.S. courts by their foreign victims via the Alien Tort Statute (ATS) without a sufficient nexus to U.S. territory. This Article contends that pursuing transnational corporate accountability unilaterally through the U.S. judiciary is inconsistent with a core tenet of liberalism itself'a state and its constituents should not be subject to the external authority of other states. This Article engages in the recurrent debate over effective transnational corporate accountability, offering the first liberalist defense of universal jurisdiction's marginalization in U.S. courts. This Article …

Are Bank Fiduciaries Special?, Robert C. Hockett

Cornell Law Faculty Publications

A growing body of post-crisis legal and economic literature suggests that future financial crises might be averted by tinkering with the internal governance structures of banks and other financial institutions. In particular, contributors to this literature propose tightening the fiduciary duties under which officers and directors of the relevant financial institutions labor. I argue in this symposium article that such proposals are doomed to failure under all circumstances save one - namely, that under which the relevant financial institutions are in whole or in part treated as publicly owned.

The argument proceeds in two parts. I first show that the …

Racial And Gender Justice In The Child Welfare And Child Support Systems, Margaret F. Brinig

Journal Articles

While divorcing couples in the United States have been studied for many years, separating unmarried couples and their children have proven more difficult to analyze. Recently there have been successful longitudinal ethnographic and survey-based studies. This piece uses documents from a single Indiana county’s unified family court (called the Probate Court) to trace the effects of race and gender on unmarried families, beginning with a sample of 386 children for whom paternity petitions were brought in four months of 2008. It confirms prior theoretical work on racial differences in noncustodial parenting and poses new questions about how incarceration and gender …

Text Messaging In The Patient-Centered Medical Home To Improve Glucose Control And Retinopathy Screening., Janice M Miller, Ann G. Phalen, Albert Crawford, Anthony Frisby, Barry S. Ziring

College of Nursing Faculty Papers & Presentations

Purpose: To evaluate the effectiveness of a text messaging program (TMP) to improve glucose control, retinopathy screening (RS) rates, and self-care behaviors in patients with uncontrolled type 2 diabetes.

Methods: A single-group design with a quasi-systematic random sample (n=20) received educational/exhortational text messages on their cellular phones for 3 months. Subjects, 12 of whom identified as a minority ethnicity, were mostly male, aged 27-73 years.

Results: Glucose control and RS rates improved significantly. Subjects (>70%) reported changes in self-care behaviors.

Conclusion: Leveraging ubiquitous technology, a TMP for patients with limited access to healthcare education, holds promise

Stop Asking Which Came First, The Jail Or The Criminal - Start Reinvesting In Justice In Maryland, Bridget Lowrie

University of Baltimore Law Forum

The numerous cries for reform of the United States criminal justice system in recent time are not without merit based on an examination of the prison population. Despite violent crime being at record low rates in the United States, the prison population has expanded tremendously. On the global stage, the United States is the leader in incarceration rates. The United States has more people incarcerated than any other country, including China, Russia, and India. Looking at a local level, Maryland is not immune to this trend. In Maryland, while violent crime is on the decline, the amount of time an …

The American Gun Culture: Potential Impact On K-12 School Violence, Gordon A. Crews, Garrison A. Crews

Criminal Justice Faculty Publications

Most researchers insist on combining all school shootings/violence incidents into one type of act and therefore one type of actor and one type of event. However, public mass shootings, university environments, international incidents, and K-12 school shootings and violence are not the same. They have different catalysts, motivations, types of occurrence, and offenders. The research for this work is part of a comprehensive examination of 78 currently incarcerated U.S. K-12 school violence offenders and their acts between 1979 and 2011 in 33 states. Topics examined include: weapons used and injuries incurred, availability of guns, where the gun or weapon …

The Association Between Secondary Mathematics And First Year University Performance In Health Sciences, C Joyce, G Hine, R Anderton

Health Sciences Papers and Journal Articles

In recent years, there has been a significant decline in the rate of participation in secondary school mathematics courses within Australia, particularly in advanced or higher level mathematics. The aim of this study was to investigate how grade point average (GPA) differed between five health science degrees at an Australian university. The association between Australian Tertiary Admission Ranking (ATAR), the level of mathematics completed at secondary school and GPA was also investigated. Results showed that students studying Biomedical Sciences and Physiotherapy had significantly higher GPA and ATAR than students studying Exercise and Sports Science, Physical Education, and Nursing. A higher …

Assessment Of R18, Cog1410, And App96-110 In Excitotoxicity And Traumatic Brain Injury, Li Shan Chiu, Ryan S. Anderton, Jane L. Cross, Vince W. Clark, Adam B. Edwards, Neville W. Knuckey, Bruno P. Meloni

Health Sciences Papers and Journal Articles

Cationic arginine-rich and poly-arginine peptides (referred to as CARPs) have potent neuroprotective properties in in vitro excitotoxicity and in vivo models of stroke. Traumatic brain injury (TBI) shares many pathophysiological processes as stroke, including excitotoxicity. Therefore, we evaluated our lead peptide, poly-arginine R18, with the COG1410 and APP96-110 peptides, which have neuroprotective actions following TBI. In an in vitro cortical neuronal glutamic acid excitotoxicity injury model, R18 was highly neuroprotective and reduced neuronal calcium influx, while COG1410 and APP96-110 displayed modest neuroprotection and were less effective at reducing calcium influx. In an impact-acceleration closed-head injury model (Marmarou model), R18, COG1410, …

Study Protocol For A Randomised Controlled Trial Evaluating The Effect Of Prenatal Omega-3 Lcpufa Supplementation To Reduce The Incidence Of Preterm Birth: The Orip Trial, Shao J. Zhou, Karen Best, Robert Gibson, Andrew Mcphee, Lisa Yelland, Julie Quinlivan, Maria Makrides

Health Sciences Papers and Journal Articles

Introduction: Preterm birth accounts for more than 85% of all perinatal complications and deaths. Seventy-five per cent of early preterm births (EPTBs) occur spontaneously and without identifiable risk factors. The need for a broadly applicable, effective strategy for primary prevention is paramount. Secondary outcomes from the docosahexaenoic acid (DHA) to Optimise Mother Infant Outcome trial showed that maternal supplementation until delivery with omega-3 (ω-3) long chain polyunsaturated fatty acid (LCPUFA), predominantly as DHA, resulted in a 50% reduction in the incidence of EPTB and an increase in the incidence of post-term induction or post-term prelabour caesarean section due to extended …

Mobile Learning Technology Acceptance Among Saudi Higher Education Students, Talal Mohammed Alasmari

Wayne State University Dissertations

The rapid development of technology has encouraged Saudi universities to establish initiatives to improve learning. Mobile learning technology is one of the technologies targeted by eLearning and distance education deanships among Saudi universities. However, few studies have been done in investigating mobile learning technology acceptance in the Saudi context. This study aims to provide policy and decision makers in the Saudi higher education with reliable data in order to employ mobile learning technology in learning process. Therefore, this study modified Unified Theory of Acceptance and Use of Technology (UTAUT) to investigate students’ acceptance of mobile learning technology. To this end, …

Reliability And Validity Of Michigan School Libraries For The 21st Century Measurement Benchmarks, Natosha Nicole Floyd

Wayne State University Dissertations

The purpose of this study was to examine the psychometric properties of the Michigan School Libraries for the 21st Century Measurement Benchmarks (SL21). The instrument consists of 19 items with three subscales: Building the 21st Century Learning Environment Subscale, Teaching for 21st Century Learning Subscale, and Leading the Way to 21st Century Learning Subscale. The sample consisted of 54 respondents who were administered the instrument in 2014 and 2015. Cronbach’s alpha for the total instrument was 0.807 (n = 19 items). Exploratory factor analysis (EFA) was used to measure construct validity. The findings derived from the EFA did not tend …

P120 Catenin Regulates Inflammation In Macrophage, Xiaoqing Guan

Wayne State University Dissertations

Objective: p120 catenin (p120ctn) has been reported to play a critical role in maintenance of the stability of adherens junctions. It also has potential anti-inflammatory effects in epithelial and endothelial cells. This research was designed to evaluate the effects of p120ctn on inflammatory responses in human macrophages upon LPS stimulation, as well as the possible mechanism by which p120ctn regulates LPS-induced proinflammatory response in macrophages. Methods: THP-1 cells were induced to differentiate into macrophages by PMA. The isoforms of p120ctn were identified via RT-PCR and Western blot. The expression of p120ctn was examined by Western blot in THP-1 derived macrophages …

Identifying The Function Of The Calpain Small Subunit In The Mechanics Of Cell Migration, Bingqing Hao

Wayne State University Dissertations

Cell migration plays a vital role in many physiological events including: morphogenesis, wound healing, and immune response. Dysfunctional cell migration results in multiple disease states including chronic inflammation, vascular disease, and tumor metastasis, to name a few. Progress in understanding the mechanism of cell migration had been slow until the turn of the century when rapid technological advances in microscopy and omics burst to the forefront. These advances led to the realization that physical factors (dimensions, fluid shear stress, hydrostatic pressure, compression stress, environmental stiffness, and topography) have profound effects on cell migration. This study of cell mechanics has expanded …

Black Male Genocide: Sanctioned Segregation In American Policy, Alton Maxel James

Wayne State University Dissertations

College degree attainment for Black Americans has significantly fallen their majority counterparts. While educational attainment for this minority demographic has been less than average, a secondary trend emerges. Despite the rises in graduation rates, Black males consistently earn a smaller percentage of the degrees garnered by Black students. Furthermore, policies throughout sectors of American society produce segregation that manifests as genocidal realities in the lives of Black men—including college graduation. Thus, the purpose of this research was to determine the effect of neighborhood segregation on Black men and women’s 4 and 6-year graduation probability and determine if Black men reduce …

Affective Dissonance: (Post)Feminism And Popular Cultural Expressions Of Motherhood, Judith Lakämper

Wayne State University Dissertations

In “Affective Dissonance: (Post)feminism and Popular Cultural Expressions of Motherhood,” I argue that motherhood in the so-called post-feminist age is structured by a conflicted relationship between affective expectations raised by public discourses of motherhood and the material, embodied experience of maternity, inflected by race, class, age, and sexuality. While recent feminist scholarship has engaged questions of (bodily) materiality, and popular medial discourses increasingly critique unrealistic ideals of motherhood, my dissertation considers these approaches together. Juxtaposing representations of motherhood from various sources – memoirs, digital media, art photography, and television – I demonstrate how the postfeminist rhetoric of female empowerment and …

A Scalable Solution For Interactive Video Streaming, Kamal Kayed Nayfeh

Wayne State University Dissertations

This dissertation presents an overall solution for interactive Near Video On Demand (NVOD) systems, where limited server and network resources prevent the system from servicing all customers’ requests. The interactive nature of recent workloads complicates matters further. Interactive requests require additional resources to be handled. This dissertation analyzes the system performance under a realistic workload using different stream merging techniques and scheduling policies. It considers a wide range of system

parameters and studies their impact on the waiting and blocking metrics. In order to improve waiting customers experience, we propose a new scheduling policy for waiting customers that is fairer …

Analysis Of The Secondary Neurodegenerative Consequences Of Primary Oligodendrocyte Stress Through The Use Of The Novel Obiden Mouse Model, Daniel Zdzislaw Radecki

Wayne State University Dissertations

The work of this project was to develop, test and characterize a potential novel mouse model of the neurodegenerative disease Multiple Sclerosis (MS). Historically, MS has been identified as a primary autoimmune disease of the central nervous system (CNS). However, treatments based on this view have met with limited success, and in most cases, fail to prevent progression of MS from mild to moderate and severe forms. Original observations regarding axonal and neuronal pathology in the white and gray matter of the CNS were rediscovered in the 1990s. These observations indicated that even in the absence of the immune system, …

Functional Analysis Of Sin3 Isoforms In Drosophila, Nirmalya Saha

Wayne State University Dissertations

he multisubunit SIN3 complex is a global transcriptional regulator. In Drosophila, a single Sin3A gene encodes different isoforms of SIN3, of which SIN3 187 and SIN3 220 are the major isoforms. Previous studies have demonstrated functional non-redundancy of SIN3 isoforms. The role of SIN3 isoforms in regulating distinct biological processes, however, is not well characterized. In addition, how the components of the SIN3 complex modulate the gene regulatory activity of the complex is not well understood. In this study, I identified the biological processes regulated by the SIN3 isoforms. Additionally, I explored how Caf1-55 impacts the gene regulatory activity of …

Actuation Of Droplets Using Transparent Graphene Electrodes For Tunable Lenses And Biomedical Applications, Ali Shahini

Wayne State University Dissertations

Variable focal length liquid microlenses are the next candidate for a wide variety of applications. Driving mechanism of the liquid lenses can be categorized into mechanical and electrical actuation. Among different actuation mechanisms, EWOD is the most common tool for actuation of the liquid lenses. In this dissertation, we have demonstrated versatile and low-cost miniature liquid lenses with graphene as electrodes. Tunable focal length is achieved by changing both curvature of the droplet using electrowetting on dielectric (EWOD) and applied pressure. Ionic liquid and KCl solution are utilized as lens liquid on the top of a flexible Teflon-coated PDMS/parylene membrane. …

Pathetic Politics: An Analysis Of Emotion And Embodiment In First Lady Rhetoric, Stephanie Lynn Wideman

Wayne State University Dissertations

This dissertation explores the theoretical and practical relationship between our understandings of emotion’s role in political decision-making. In this pursuit I seek a resurrection for pathos’s legitimacy in persuasive studies through the pursuit of the pathetic political realm. This work has three primary concerns: how may pathetic power be accessed, from where does this power originate, and how might political actors enact this power for their own political goals. I draw primarily from theories related to visual rhetoric and the body in order to provide perspective on how the body is politicized through the pathetic realm. Theoretical perspectives are drawn …

Self-Efficacy: Understanding African American Male Students Pathways To Confidence In Mathematics, Lisa Ann Williams

Wayne State University Dissertations

This dissertation is about the stories of African American male undergraduate students who have experienced success in mathematics. Bandura’s (1997) social cognitive theory and Tillman’s (2000) culturally sensitive research approach which promotes qualitative methods, recognizes ethnicity, and positions culture as central to the research were applied. Student interviews, parent interviews, teacher interviews, and mathematical autobiographies were used to investigate African American men self-efficacy, the sources of their beliefs, and societal factors that impacted their motivation and academic achievement in mathematics.

The descriptive portraits and the interviews revealed five broad themes: (1) college experiences, (2) K-12 experiences, (3) access and equity, …

Identification Of Oxygen Optima For Mouse Trophoblast Stem Cells And Human Embryos And The Stress Responses Upon Departing Optima, Yu Yang

Wayne State University Dissertations

Low level of oxygen (O2) occurs physiologically during in vivo embryo development. As developing embryos moving from fallopian tube to uterus, oxygen level gradually decreases to ≤ 5% at the time of blastocyst implantation. Blastocysts are made of two major cell populations, trophoblast cells and inner cell mass, from which trophoblast stem cells (TSCs) and embryonic stem cells (ESCs) are derived respectively. TSCs serve as placental stem cells that later on proliferate and differentiate into placenta. Previous study has shown that 2% O2 is the optimal O2 level for mTSC in vitro growth and potency maintenance, which agrees with their …

Effect Of Endoplasmic Reticulum Stress On Vascular Smooth Muscle Cells And Its Regulation Of Sm22Α, Neeraja Priyanka Annam

Wayne State University Dissertations

Background: The vascular smooth muscle cells(VSMC) possess the ability to differentiate into a synthetic phenotype in response to stress. This phenotypic modulation may be accompanied by inflammatory or osteogenic response in chronic stress. The synthetic state is characterized by low levels of contractile markers unlike the differentiated state.

Hypothesis: Endoplasmic reticulum (ER) stress causes phenotypic modulation in VSMCs leading to apoptosis. Many transcription factors induced by ER stress contribute to the downregulation of Sm22α. Perturbation in cytoskeletal dynamics exacerbates the ER stress response.

Methods: Ex-vivo culture was used to establish importance of Sm22 in ER stress. In vitro analysis was …