Digital Commons Network^™

Outcomes Of High Risk Patients With Febrile Neutropenia At A Tertiary Care Center, Asif Husain Osmani, Adnan Abdul Jabbar, Manesh Kumar Gangwani, Bilal Hassan

Department of Radiation Oncology

Creative Commons Attribution LicenseFever during chemotherapy-induced neutropenia continues to be a major cause of morbidity and mortality incancer patients. Mortality depends on the duration and degree of neutropenia, bacteremia, sepsis, performance status,comorbidities and other parameters. The highest mortality rates in cancer patients hospitalized with febrile neutropenia(FN) are observed in those with documented infection. The objectives of the study were to present available tools forrisk assessment, to review pathogens causing infections in adult FN patients and to assess outcomes. Methods: Thiscross sectional study was conducted on adult culture positive FN patients admitted to the Hematology/Oncologyservice at the Aga Khan University Hospital, …

Healthy Lifestyle Of Nurses And Nursing Students, Walter De Caro, Elisabetta Corvo, Julita Sansoni

Biennial Convention (CONV)

Nurses in their role of health promoter are well situated to address the increasing burden of NCDs which are the main cause of mortality worldwide. However literature indicates that nurses often do not have a healthy lifestyle.

Isolation, Detection, And Prevention Of Foodborne Bacteria In Irrigation Water And Dairy Food, Mohammed Saleemallah Alhejaili

LSU Doctoral Dissertations

Foodborne microorganisms can be beneficial to humans or cause disease. Salmonella is one of the most causative foodborne disease outbreaks in the U.S.A. Salmonella has been detected in surface water used in irrigation, and can survive for weeks to years in water. The purpose of the study was to detect low levels of Salmonella spp. by comparing surfactant modified zeolite (SMZ) filtration and Activated Carbon (AC) filtration with the Environmental Protection Agency (EPA) method 1200. Also, to determine the generic E.coli counts and if there was a direct correlation of Salmonella to generic E. coli in irrigation water. The EPA …

Uab Physician Named To 2017 National Academy Of Medicine Fellows, Staff

Browse All News

No abstract provided.

Spartan Daily, October 24, 2017, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2017

Volume 149, Issue 26

Qi Assessment Of Attending Physician Burnout At Lehigh Valley Health Network (Lvhn) Using The Maslach Burnout Inventory (Mbi)., Pooja Shankar Md, Suzanne J. Templer Do

Department of Medicine

No abstract provided.

Why Informed Consent? Human Experimentation And The Ethics Of Autonomy, Richard W. Garnett

The Catholic Lawyer

No abstract provided.

Science Phobic?: Professor Frank Fekete Can Fix That - And, Perhaps, Some Global Problems, Abukar Adan

Colby Magazine

"It shouldn't be a surprise. Of any subdiscipline in biology, microbiology is the most relevant to my students' lives because everyone is concerned about his or her health." - Frank Fekete, professor of biology

The Social, Economic, And Public Health Consequences Of Global Population Aging: Implications For Social Work Practice And Public Policy, Mitchell A. Kaplan, Marian M. Inguanzo

Journal of Social Work in the Global Community

Human populations around the world are growing older at the most astounding rate in the history of humanity. Advances in technology are enabling health care providers to deliver the latest innovations in treatment and prevention services to a broader spectrum of adult populations across the lifespan making longevity increasingly more commonplace rather than the exception to the rule in most of the industrialized world. This article provides an overview of the key social, economic, and public health costs and consequences that aging populations will exact upon international communities in the years ahead. It also examines the most significant social challenges …

What's Happening: October 23, 2017, Maine Medical Center

What's Happening

No abstract provided.

Emerging Hotspot Analysis Of Florida Manatee (Trichechus Manatus Latirostris) Mortality (1974-2012), Crystal Ann Bass

HCNSO Student Theses and Dissertations

The Florida manatee (Trichechus manatus latirostris) is a protected species that is vulnerable to both anthropogenic and natural causes of mortality. The ability of wildlife managers to oversee regulation of this species is based on available abundance estimates and mortality data. Using existing manatee mortality data collected by Florida Fish and Wildlife Conservation Commission (FWC) from 1974-2012, this study focuses on identifying significant spatial clusters of high values or “hotspots” of manatee mortality and the temporal patterns of these hotspots using the novel “emerging hotspot analysis” ArcGIS tool. The categories of manatee mortality included in this analysis were …

Campus-Based Health Information Campaign Using Bluetooth 4.0 Low Energy Device (Ibeacons), Sharewin Q. Jr. Pulido, Jenica Ana Rivero

Biennial Convention (CONV)

Technological development has greatly impacted the manner in which health services are rendered. In this inquiry, we looked at the potential of Bluetooth low energy (iBeacons) as a tool for health information dissemination. Furthermore, we offer implication on the use of iBeacons in education, research, and practice.

The Effectiveness Of Combined Appointments And Influenza Immunization Rates In A Rural Wic Population, Lisa L. Sitler

Biennial Convention (CONV)

Understanding how to increase childhood influenza immunizations is necessary for prevention of illness. The purpose of this activity is to examine predictors and barriers to influenza immunization in a rural low-income WIC population. Implementation of these results may also increase overall rates of childhood immunizations.

Is Tb Testing Associated With Increased Blood Interferon-Gamma Levels?, Aideen E. Kennedy, Jim O'Mahony, Noel Byrne, John Macsharry, Riona G. Sayers

Department of Biological Sciences Publications

The Republic of Ireland reports a relatively low prevalence of Johne’s disease (JD) compared to international counterparts. Postulated reasons for this include a lower average herd size and a grass-based production system. Ireland also engages in high levels of bovine tuberculosis (bTB) testing. As interferon-gamma (IFN-γ) is believed to play a key role in protecting against JD, it is our hypothesis that administration of purified protein derivative (PPD), as part of the bTB test, is associated with a systemic increase in IFN-γ production, which may potentially limit clinical progression of the disease. We studied 265 cows (202 Friesian and 63 …

Medical School Watercooler Newsletter - October 22, 2017, Lindsey Lyle

Watercooler Newsletter

This is the October 22, 2017 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Dr. Christopher Anderson to Present Frazer/Leigh Memorial Lecture

Med School Café- Expert Advice For the Community

Mark Your Calendar: Upcoming Town Hall Meeting

Dr. Richard Honkanen Collaborates with Leading Researchers Across the Globe in Search of Treatment for Rare Disease

USA Welcomes Dr. Jin H. Kim

This Week: Rainbow Cancer Walk-A-Thon

October 20, 2017, Ohio University Board Of Trustees Meeting Minutes, Ohio University Board Of Trustees

Board of Trustees Meeting Minutes

Meeting minutes document the activities of Ohio University's Board of Trustees.

Critical Appraisal To Intraabdominal And Complicated Intraabdominal Guidelines To Develop Indonesian Specific Clinical Practice Guidelines, Yefta Moenadjat, Dina D. Mulya, Toar Jm. Lalisang

The New Ropanasuri Journal of Surgery

Introduction. There were many clinical practice guidelines (CPG) intraabdominal infection/complicated intraabdominal infections (cIAI) have been developed since 1992 and were periodically updated recently. But to date, the implementation in Indonesia encountering problems. One is Indonesian characteristics which is differed to the population of where the CPG developed. To adapt a CPG, the quality of CPG should be first critically appraised. The best will be used furthers as the subject to be adapted, with modification regarding Indonesian characteristics. Method. A literature search carried out on guidelines databases to find out CPG on cIAI (1992–2017). The assessment preceded using AGREE II tools …

Kinetic Characterization Of Listeria Monocytogenes 2-C- Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase ( Cms ) Enzymes Using High Performance Liquid Chromatography ( Hplc ), Mark Oblazny

Theses and Dissertations

Infectious diseases, with increasing prevalence of antibiotic resistant bacteria, coupled with the declining rate in discovery of antimicrobial agents, impose one of the most significant threats to human health. Here we identify 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (CMS) as a valid target for antibiotic development which is an enzyme in pathogenic organisms that leads to the biosynthesis of isoprene precursor molecules. Isoprene molecules are one of nature’s most common building blocks that are vital to many biological metabolic processes and are synthesized via the mevalonic acid dependent (MVA), or methylerythritol phosphate (MEP) pathway. Vertebrates utilize the MVA pathway, while many pathogenic bacteria …

The Biochemical Assessment Of Two Secreted Acid Phosphatases From Leishmania Tarentolae, Their Response To Electric Fields, Glycosidase Incubation, And / Or Vanadium, Benjamin M. Dorsey

Theses and Dissertations

Leishmaniasis, as defined by the Center for Disease Control and Prevention, is a neglected tropical disease with 1.6 million new cases reported each year. However, there is yet to be safe, effective, and affordable treatments provided to those affected by this disease1. Still underappreciated as a potential pharmaceutical targets, especially for cutaneous leishmaniasis infections, are the two isozymes of secreted acid phosphatase (SAP); secreted acid phosphatase 1 (SAP1) and secreted acid phosphatase 2 (SAP2). These enzymes are involved in the survival of the parasite in the sand fly vector, and the prevention of host macrophages from forming parasitophorous vacuole and …

Single-Use Disposable Commode Pan/Bedpan Liners To Reduce Future Risk Of Hospital-Acquired Clostridium Difficile Infection, Brenda L. Jenkins

Biennial Convention (CONV)

The history and evolution of the pilot project developed is in reference to the first hospital acquired (HA) Clostridium difficile infection (CDI) outbreak in a rural hospital within western Canada and how one can best manage human fecal waste to decrease the likelihood of HA inpatient transmission.

Student Pharmacists And Street Children: A Mutually Beneficial Relationship, Mario A. Hoyos, Monica L. Miller, Ellen M. Schellhase, C. Ryan Tomlin, Sonak Pastakia, Samuel Kimani, Tim Mercer

Purdue Journal of Service-Learning and International Engagement

The Tumaini Children’s Drop-In Center is a daytime drop-in center for the street children of Eldoret, Kenya. It is part of a partnership between the Purdue University College of Pharmacy, the Academic Model Providing Access to Healthcare program, Eldoret community members, and numerous individuals in both Kenya and the US. Through the efforts of local staff and Purdue student pharmacists, who work at the local hospital on an eight-week clinical rotation, the center has helped a population of nearly 400 local street children by providing a safe haven from life on the streets. Purdue student pharmacists aid the center by …

Developing A Mobile Application: Improving Health Care Students’ Ability To Communicate, Kiersten Walters, Ilya Rybakov, Patricia L. Darbishire

Purdue Journal of Service-Learning and International Engagement

The purpose of this project was to develop, pilot, assess, and describe a new interdisciplinary, game-based phone application. The application is intended to help health care students better communicate medication and medical terminology to their patients and to other health care providers and insurance companies. This IRB-approved project called “PharmPhrase” was developed using an application-development software program. The pilot involved multiple groups of competing teams composed of volunteer pharmacy students in their first professional years who were randomly assigned into teams of three to five. The PharmPhrase user explains a randomly generated medical term to team members based on assumptions …

Expanding The Horizon: Global Health Management For Pharmacy Students, Alice C. Chang, Monica L. Miller, Ellen M. Schellhase

Purdue Journal of Service-Learning and International Engagement

The advancement of global engagement opportunities will promote pharmacy students’ cultural awareness and sensitivity, expose students to treatment of diseases not commonly seen in modern Western medicine, and cultivate future leadership for the growth of global pharmacy practice. At Purdue University College of Pharmacy (PUCOP), limited opportunities exist for student pharmacists. As a result, identifying the needs and expanding student pharmacist access to global engagement experiences are critical to meet the changing needs of the US population. A survey was developed and distributed to 460 students at PUCOP, and 148 of them participated. Of those students, 89.2% were interested in …

Lung Cytokines And Systemic Inflammation In Patients With Copd, Alessandra Morello Gearhart, Rodrigo Cavallazzi, Paula Peyrani, Timothy L. Wiemken, Stephen P. Furmanek, Andrea Reyes-Vega, Umair Gauhar, Hiram Rivas-Perez, Jesse Roman, Julio A. Ramirez, Rafael Fernandez-Botran

The University of Louisville Journal of Respiratory Infections

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by lung and systemic inflammation. The role of cytokines in local and systemic inflammation in COPD is not well understood. This study aimed to compare plasma and bronchoalveolar lavage (BAL) fluid cytokine levels in COPD and non-COPD subjects with the intent of better understand their potential roles in driving local and systemic inflammation.

Methods: This cross-sectional study analyzed data from 65 subjects: 31 with COPD confirmed by spirometry and 34 non-COPD controls. All subjects underwent spirometry, plasma sample collection, and bronchoscopy/BAL. Levels of 21 inflammatory cytokines were measured in the plasma (systemic …

Using Steroids In Patients With Community-Acquired Pneumonia At The University Of Louisville Hospital: Who, What, And When, Rodrigo Cavallazzi, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Lung Cytokines And Systemic Inflammation In Patients With Copd., Alessandra Morello Gearhart, Rodrigo Cavallazzi, Paula Peyrani, Timothy L. Wiemken, Stephen P. Furmanek, Andrea Reyes-Vega, Umair Gauhar, Hiram Rivas-Perez, Jesse Roman, Julio A. Ramirez, Rafael Fernandez-Botran

Faculty and Staff Scholarship

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by lung and systemic inflammation. The role of cytokines in local and systemic inflammation in COPD is not well understood. This study aimed to compare plasma and bronchoalveolar lavage (BAL) fluid cytokine levels in COPD and non-COPD subjects with the intent of better understand their potential roles in driving local and systemic inflammation.

Methods: This cross-sectional study analyzed data from 65 subjects: 31 with COPD confirmed by spirometry and 34 non-COPD controls. All subjects underwent spirometry, plasma sample collection, and bronchoscopy/BAL. Levels of 21 inflammatory cytokines were measured in the plasma (systemic …

Differential Roles For Inner Membrane Complex Proteins Across Toxoplasma Gondii And Sarcocystis Neurona Development, Rashmi Dubey, Brooke Harrison, Sriveny Dangoudoubiyam, Giulia Bandini, Katherine Cheng, Aziz Kosber, Carolina Agop-Nersesian, Daniel K. Howe, John Samuelson, David J. P. Ferguson, Marc-Jan Gubbels

Maxwell H. Gluck Equine Research Center Faculty Publications

The inner membrane complex (IMC) of apicomplexan parasites contains a network of intermediate filament-like proteins. The 14 alveolin domain-containing IMC proteins in Toxoplasma gondii fall into different groups defined by their distinct spatiotemporal dynamics during the internal budding process of tachyzoites. Here, we analyzed representatives of different IMC protein groups across all stages of the Toxoplasma life cycle and during Sarcocystis neurona asexual development. We found that across asexually dividing Toxoplasma stages, IMC7 is present exclusively in the mother’s cytoskeleton, whereas IMC1 and IMC3 are both present in mother and daughter cytoskeletons (IMC3 is strongly enriched in daughter buds). In …

Volume 55, Number 10: October 18, 2017, University Of North Dakota

University Letter Archive

No abstract provided.

The Utilization Of Short Message Service (Sms) In Promoting Community Maternal Health, Felin Nida Corrales Casing, Ellayza Narciso Blas

Biennial Convention (CONV)

The study gives emphasis to health teaching among Filipino mothers through the utilization of short message system (SMS) and distribution of pamphlets. The results suggest significant improvement in the cognitive scores of the control group and experimental group. Findings shows that SMS and pamphlets are comparable in disseminating health information.

Cd80 Expressed By Cd8+ T Cells Contributes To Pd-L1-Induced Apoptosis Of Activated Cd8+ T Cells, Meagan R. Rollins, Rachel M. Gibbons Johnson

Biology Publications

Tumor cells are capable of limiting antitumor CD8+ T cell responses through their cell surface expression of PD-L1. In addition to PD-1 expressed by CD8+ T cells, PD-L1 also binds to CD80 expressed by CD8+ T cells. The influence of the PD-L1/CD80 interaction on CD8+ T cell function has not been fully characterized, so we sought to investigate the impact of the PD-L1/CD80 interaction on PD-L1-induced apoptosis of activated CD8+ T cells. We found that CD8+ T cells that lacked CD80 expression got activated to the same extent as wild-type CD8+ T cells, but when cultured with anti-CD3 and PD-L1/Fc …