Digital Commons Network^™

Spatial-Temporal Distribution Of Mosquito Larval Hot Spots In Papoli, Uganda: A Community-Based Approach To Mosquito Control, Ryan E. Tokarz

USF Tampa Graduate Theses and Dissertations

Mosquito species of the Anopheles gambaie complex are the predominant vectors of malaria transmission throughout sub-Saharan Africa. These mosquitoes tend to be endophilic, as well as anthropophilic, making them prime candidates for disease transmission. Within the same region, related mosquito vectors play a significant role in the transmission of additional human and zoonotic diseases. Furthermore, mosquito nuisance biting is an immense issue that cannot be ignored in terms of its impact on African communities. Depending on the respective factors involved, mosquito control programs throughout the continent have attempted to tackle these issues in a multitude of ways. This research approached …

Msaabcr Operon Is Involved In Persister Cell Formation In Staphylococcus Aureus, Gyan S. Sahukhal, Shanti Pandey, Mohamed O. Elasri

Faculty Publications

Background

Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in treatment failures of bacterial infections. While this phenomenon has posed a great threat in public health, mechanisms underlying their formation in Staphylococcus aureus remain largely unknown. Increasing evidences of the presence of persister cells in recalcitrant infections underscores the great urgency to unravel the mechanism by which these cells develop. Previously, we characterized msaABCR operon that plays roles in regulation of virulence, biofilm development and antibiotic resistance. We also characterized the function of MsaB protein and showed that MsaB is a putative transcription factor that binds …

Development Of A Broadly Protective Modified-Live Virus Vaccine Candidate Against Porcine Reproductive And Respiratory Syndrome Virus, Haiyan Sun, Aspen Workman, Fernando A. Osorio, David J. Steffen, Hiep L.X. Vu

Nebraska Center for Virology: Faculty Publications

Modified-live virus (MLV) vaccines are widely used to protect pigs against porcine reproductive and respiratory syndrome virus (PRRSV). However, current MLV vaccines do not confer adequate levels of heterologous protection, presumably due to the substantial genetic diversity of PRRSV isolates circulating in the field. To overcome this genetic variation challenge, we recently generated a synthetic PRRSV strain containing a consensus genomic sequence of PRRSV-2. We demonstrated that our synthetic PRRSV strain confers unprecedented levels of heterologous protection. However, the synthetic PRRSV strain at passage 1 (hereafter designated CON-P1) is highly virulent and therefore, is not suitable to be used as …

Managing Toxicities Associated With Immune Checkpoint Inhibitors: Consensus Recommendations From The Society For Immunotherapy Of Cancer (Sitc) Toxicity Management Working Group., I. Puzanov, A. Diab, K. Abdallah, C. O. Bingham, C. Brogdon, R. Dadu, L. Hamad, S. Kim, M. E. Lacouture, N. R. Leboeuf, D. Lenihan, C. Onofrei, V. Shannon, R. Sharma, A. W. Silk, D. Skondra, M. E. Suarez-Almazor, Y. Wang, K. Wiley, H. L. Kaufman, M. S. Ernstoff, J. Anderson, K. Lehman, D. Reshef, A. Saylors, M. Turner, I. Waxman, D. Arrindell, S. Andrews, J. Ballesteros, J. Boyer, I. Cotarla, M. Dawson, T. Goswami, V. Hayreh, W. Holmes, Z. Rasheed, M. Sarkeshik, J. Schreiber, K. Shafer-Weaver, D. Chen, S. Ley-Acosta, D. Chonzi, W. Go, R. Cunha, J. L. Gulley, L. Wood, M. Davies, Adam Dicker, L. Eifler, N. Gregory, A. Ferguson, C. Ferlini, S. Frankel, C. Gochett, J. Goldberg, K. Patel, D. Wariabharaj, P. Goncalves, N. Helie, J. Y. Hsu, R. Ibrahim, C. Larocca, O. Lambotte, J. Luke, J. Mcclure, E. Michelon, M. Nakamura, B. Piperdi, J. Riemer, C. Robert, W. Sharfman, E. Sharon, R. Sherry, C. Simonson, C. Thomas, E. Trehu, J. A. Thompson, D. Tresnan, L. Zhang, P. Zheng

Department of Radiation Oncology Faculty Papers

Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse events (irAEs). Many of these are driven by the same immunologic mechanisms responsible for the drugs' therapeutic effects, namely blockade of inhibitory mechanisms that suppress the immune system and protect body tissues from an unconstrained acute or chronic immune response. Skin, gut, endocrine, lung and musculoskeletal irAEs are relatively common, whereas cardiovascular, hematologic, renal, neurologic and ophthalmologic irAEs occur much less frequently. The majority of irAEs …

Uab Celebrates World Aids Day By Partnering With Local Agencies, Staff

Browse All News

No abstract provided.

Grand Valley Forum, Volume 042, Number 07, November 20, 2017, Grand Valley State University

2017-2018, Volume 42

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Week Of November 20, 2017, New York Medical College

InTouch

• The Music of Mozart Comes Alive at Met
• StuHE Hosts Career Mentor Session
• SHSP Weighs In at APHA 2017
• NYMC Welcomes Human Rights Institute for Middle School Student Leaders to Campus

Molecular Detection Of Erwinia Herbicola Isolated From Nuts, Suaad Abid Fazaa Al-Miyah

Muthanna Medical Journal

Food borne pathogens are major impediment of the public health and economic development, mostly Enterobacteriaceae is inherent foodborne pathogens of which E. herbicola have recently emerged significant in ready eat food. The aim of this study was to determine quantitatively of viable bacterial isolates and molecular diagnosis of Erwinia herbicola by SYBR Green real-time PCR in nuts. The bacterial species isolates of nuts are Coagulase + Staphylococcus, E. coli, Enterobacter cloacae and Erwinia herbicola. The highest rate of Coagulase + Staphylococcus species of two hazelnuts and two cashew samples and Erwinia herbicola of one almond sample, theses bacterial isolates from …

Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo

Spora: A Journal of Biomathematics

Tasmanian devil populations have been devastated by devil facial tumor disease (DFTD) since its first appearance in 1996. The average lifespan of a devil has decreased from six years to three years. We present an age-structured model to represent how the disease has affected the age and breeding structures of the population. We show that with the recent increase in the breeding of juvenile devils, the overall devil population will increase but not nearly to pre-DFTD levels. The basic reproductive number may be increased with the influx of young breeding devils. In addition, our model shows that the release of …

Cultural Competency In Effective Medical Missions, Abigail Drogosz

Grace Peterson Nursing Research Colloquium

Abstract

Background: Every year medical professionals and volunteers travel internationally to provide services to individuals in need. However, some times these trips can be more detrimental than helpful. This can be due to the fact that these trips are self-serving in which they provide value for visitors without meeting the local community needs (Unite for Site, 2015). Secondly, they raise unmet expectations due to language barriers or lack of medical training for particular diseases. In addition, they may provide culturally irrelevant or inadequate care to the communities they are serving. Lastly, these missions may not follow current standards of health …

O'Day, Janet, Johnna Ossie

Querying the Past: LGBTQ Maine Oral History Project Collection

Janet O'Day is 71 years old. She lives in Maine with her wife, Rosemary. She has one adult son. She was raised in a Catholic Family in Quincy, Massachusettes. She came out later in life after being married to a man and having a son. Religion is important to Janet and she was involved with Dignity in Boston and Maine, an organization that provides Catholic Mass and religious support to Catholic LGBTQ people. Janet continues to stay involved in her church community. During the HIV/AIDS epidemic, Janet worked at the Deaconness hospital in Boston as a discharge nurse with patients …

Flu Vaccines Provided To Birmingham's Homeless Community At No Cost, Alicia Rohan

Browse All News

No abstract provided.

November 17, 2017, The Dakota Student

The Dakota Student

No abstract provided.

Compassionate Healthcare, Krysten Godfrey Maddocks

UNH Today Archive

No abstract provided.

The Association Between Gastro-Oesophageal Reflux Disease And Subsequent Rheumatoid Arthritis Occurrence: A Nested Case–Control Study From Taiwan, Herng-Ching Lin, Sudha Xirasagar, Cha-Ze Lee, Chung-Chien Huang, Chao-Hung Chen

Faculty Publications

Objective Gastro-oesophageal reflux disease (GORD) is a common comorbidity among patients with rheumatoid arthritis (RA). While GORD has been attributed to the antirheumatic medications, no studies of human cohorts have investigated a link between GORD and RA. This study investigates whether GORD is associated with a subsequent RA diagnosis over a 5-year follow-up using a population-based dataset.

Setting Taiwan

Participants We used data from the Taiwan Longitudinal Health Insurance Database. The study group consisted of 13 645 patients with an ambulatory claim showing a GORD diagnosis. We used propensity score matching to select 13 645 comparison patients (one per study …

Cost-Effectiveness Analysis Of Targeted Herpes Zoster Vaccination In Adults 50-59 At Increased Cardiovascular Risk, Kathleen M. Glassner

USF Tampa Graduate Theses and Dissertations

Background: Over the last twenty years the incidence of herpes zoster (HZ) infection, also known as shingles, has been increasing among adults for unknown reasons. The economic burden of HZ is currently estimated at over $1 billion per year in the United States (U.S.) and is expected to increase as the susceptible adult population ages. HZ is caused by a re-activation of the varicella zoster virus (VZV), chicken pox, and more than 95% of adults living today carry the virus with a lifetime risk of 1 in 3 for developing HZ. In 2006 the FDA approved a vaccine for the …

Don't Let Fall Allergies Leave You In The Cold, Alicia Rohan

Browse All News

No abstract provided.

Vista: November 16, 2017, University Of San Diego

USD Vista (1965-)

No abstract provided.

Evaluation Of A Microsphere-Based Immunoassay (Mia) In Measuring Diagnostic And Prognostic Markers Of Dengue Virus Infection, Jason H. Ambrose

USF Tampa Graduate Theses and Dissertations

Infections with dengue viruses (DENV) constitute both a global problem as well as locally in Florida. DENV comprise four distinct serotypes of single-stranded RNA viruses and belong to the family Flaviviridae. DENV are among the most medically important arboviruses in the world and cases may currently exceed 400 million per annum. Additionally, dengue established its first recorded endemic transmission cycle in the state of Florida in over a half century, first within the Florida Keys during 2009-10 followed by an unrelated outbreak in Martin County in 2013. The clinical profile of DENV infections ranges from a mild febrile illness …

Please Expect Turbulence: Liability For Communicable Disease Transmission During Air Travel, Kathryn Brown

DePaul Law Review

No abstract provided.

News In Brief

Jefferson Surgical Solutions

Promotions and Advancement

Luis Eraso, MD, (Division of Vascular Surgery), and John Kairys, MD, FACS (Division of General Surgery), have each been promoted to Associate Professor of Surgery.

Orlando Kirton, MD, FACS, has been named Vice Chair, Chief of Surgery at Abington Hospital.

Jack Sariego, MD, FACS, has been named Vice Chair, Chief of Surgery at Aria.

Alliric Willis, MD, FACS, has been named Vice Chair for Faculty Affairs & Faculty Development.

Save the Date

Please join us on Tuesday, November 28, 2017, at the 15th Annual Jefferson Gala. Chair of Surgery, Charles J. Yeo, MD, FACS, will receive the …

Grateful Patient Recognizes Acute Care Surgery, Infectious Disease Teams For Life-Saving Treatment

Jefferson Surgical Solutions

Robert Petcove has spent nearly three decades helping hospitals and health systems provide benefits to their employees. Yet, until this year, impacted wisdom teeth had been the Cherry Hill, New Jersey, native’s biggest health issue. That changed over Mother’s Day weekend – when a couple of fluke accidents culminated in a life-threatening Strep A infection.

“On Mother’s Day, I cut my right forearm as I was cleaning out an old aquarium,” Petcove, 48, recalls. “It was a very small cut that barely bled, but since I’m familiar with fish tank diseases that can be transmitted to humans, I cleaned it …

Surgeon Speaks

Jefferson Surgical Solutions

Like every surgeon, I started my residency training in General Surgery. Then I specialized in Thoracic and Cardiovascular Surgery and finally sub-specialized with a Fellowship in Heart and Lung Transplantation and Adult Cardiac Surgery at Duke University Medical Center. At the time I went through training, we didn’t have a lot of good options to help patients with advanced heart failure. I was working with very sick patients, many of whom died.

Back then, many of my colleagues questioned why I would choose this as my focus. They were right that the treatments weren’t great at the time. But over …

At The Heart Of Innovation: Jefferson’S Heart Transplant Program

Jefferson Surgical Solutions

Jefferson’s Heart Transplant Program reactivated this year with a new, system-wide approach to heart failure that makes innovative, evidence-based, comprehensive care more accessible to patients throughout the Delaware Valley. The program is led by surgeon H. Todd Massey, MD, as Surgical Director of Cardiac Transplantation and Mechanical Circulatory Support and cardiologist Andrew Boyle, MD, as Medical Director of Advanced Heart Failure.

“By implementing consistent standards at all Jefferson Health locations, patients with end-stage heart failure can receive the same care whether they come to Center City, see physicians at Abington or Aria or interact with us through our JeffConnect telehealth …

Comparison Of Outcomes Of Antibiotic Drugs And Appendectomy (Coda) Trial: A Protocol For The Pragmatic Randomised Study Of Appendicitis Treatment., Giana H Davidson, David R Flum, David A Talan, Larry G Kessler, Danielle C Lavallee, Bonnie J Bizzell, Farhood Farjah, Skye D Stewart, Anusha Krishnadasan, Erin E Carney, Erika M Wolff, Bryan A Comstock, Sarah E Monsell, Patrick J Heagerty, Annie P Ehlers, Daniel A Deugarte, Amy H Kaji, Heather L Evans, Julianna T Yu, Katherine Mandell, Ian C Doten, Kevin S Clive, Karen M Mcgrane, Brandon C Tudor, Careen S Foster, Darin J Saltzman, Richard C Thirlby, Erin O Lange, Amber K Sabbatini, Gregory J Moran

Articles, Abstracts, and Reports

INTRODUCTION: Several European studies suggest that some patients with appendicitis can be treated safely with antibiotics. A portion of patients eventually undergo appendectomy within a year, with 10%-15% failing to respond in the initial period and a similar additional proportion with suspected recurrent episodes requiring appendectomy. Nearly all patients with appendicitis in the USA are still treated with surgery. A rigorous comparative effectiveness trial in the USA that is sufficiently large and pragmatic to incorporate usual variations in care and measures the patient experience is needed to determine whether antibiotics are as good as appendectomy.

OBJECTIVES: The Comparing Outcomes of …

2017-18 Key Strategic Issues List, Todd E. Key Col

Articles & Editorials

For over a decade, the USAWC has published the annual Key Strategic Issues List (KSIL) to inform students, faculty, and external research associates of strategic topics requiring research and analysis. Part I of the Academic Year (AY) 2018 KSIL, referred to as the Chief of Staff of the Army Special Interest Topics, consists of critical topics demanding special attention. A subset of these topics will be addressed by the USAWC as Integrated Research Projects. Part II: Army Priorities for Strategic Analysis, has been developed by the U.S. Army War College in coordination with Headquarters Department of the Army (HQDA) and …

Reforming Prison Policy To Improve Women-Specific Health And Sanitary Care Conditions Of Prisons In Ethiopia, Behailu T. Weldeyohannes

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.

November 2017, Randy Curry, Cindy Brooks

RURAL ROCKS

Rural Rocks, the Rural Health Network newsletter by the SWOSU College of Pharmacy

Royal Daughters In Anglo-Saxon England, Alice Wehling

History ETDs

This thesis seeks to investigate the social roles of royal daughters in Anglo-Saxon England. The daughters of Anglo-Saxon kings were raised in monasteries or in the royal households of their parents, and were educated in accordance with their royal status. Through their marriages to the rulers of other kingdoms, royal daughters served as the primary vehicles by which Anglo-Saxon ruling dynasties made political alliances with their domestic and continental neighbors. Royal daughters could also be consecrated to the religious life; as nuns and abbesses of prominent monastic institutions, these women served their family’s spiritual interests and wielded substantial spiritual and …

Mode Of Delivery And Child And Adolescent Psychological Well-Being: Evidence From Hong Kong’S “Children Of 1997” Birth Cohort, Cherry Y. Leung, Gabriel M. Leung, C. Mary Schooling

Publications and Research

Mode of delivery (vaginal or cesarean section) is thought to affect gut microbiota, which in turn may affect psychological well-being. As such, mode of delivery is potentially a modifiable factor for psychological well-being. Here we examined the association of mode of delivery with child and adolescent psychological well-being. We used multivariable linear regression in a populationrepresentative Hong Kong Chinese birth cohort, “Children of 1997,” to examine the adjusted associations of mode of delivery with behavioral problems assessed from parent-reported Rutter score at ~7 (n = 6294) and ~11 years (n = 5598), self-esteem assessed from self-reported Culture-Free Self- Esteem Inventory …