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ผลฉับพลันของการออกกำลังกายแบบแอโรบิคระหว่างปริมาณออกซิเจนปกติและปริมาณออกซิเจนต่ำความดันบรรยากาศปกติที่มีต่อชีวกลศาสตร์ของการขยายทรวงอกขณะหายใจ, ต้อง คงวิเศษ

Chulalongkorn University Theses and Dissertations (Chula ETD)

วัตถุประสงค์: เพื่อศึกษารูปแบบการหายใจจากการเปลี่ยนแปลงปริมาตรทรวงอกทั้ง 4 ส่วน ได้แก่ ทรวงอกส่วนบน (Superior thoracic: ST) ทรวงอกส่วนล่าง (Inferior thoracic: IT) ช่องท้องส่วนบน (Superior abdomen: SA) และ ช่องท้องส่วนล่าง (Inferior abdomen: IA) หลังการออกกำลังกายแบบแอโรบิกระหว่างสภาวะออกซิเจนปกติ และสภาวะออกซิเจนต่ำ ความดันปกติ (ปริมาณ O2 15%) วิธีดำเนินการวิจัย: กลุ่มตัวอย่างที่ใช้ในการวิจัยครั้งนี้เป็นนิสิตนักศึกษา และนักกีฬาสมัครเล่นชมรมฟุตซอล จำนวน14 คน อายุ 18-25 ปี มีอายุเฉลี่ย 19.93 ± 1.14 ปี ส่วนสูงเฉลี่ย 173.71± 4.65 ซม น้ำหนัก 63.79 ± 7.28 kg เก็บข้อมูลโดยการวิเคราะห์จากภาพ 3 มิติ โดยทำการติดตั้ง Marker บริเวณช่วงลำตัวทั้งหมด 30 จุด บันทึกภาพรูปแบบการหายใจ ก่อน และหลังการออกกำลังกายทันทีโดยกล้องความเร็วสูง จำนวน 6 ตัว วิเคราะห์ข้อมูลโดยโปรแกรมวิเคราะห์การเคลื่อนไหว Qualisys Motion Capture System เพื่อนำมาคำนวณการเปลี่ยนแปลงปริมาตรหลังการออกกำลังกายแบบแอโรบิก ในสภาวะออกซิเจนปกติ และสภาวะออกซิเจนต่ำ ความดันปกติ ในแต่ละส่วน เปรียบเทียบผลการวิจัยก่อน-หลังการฝึก และ ระหว่างสภาวะ โดยใช้ pair t- test กำหนดระดับความมีนัยสำคัญทางสถิติที่ p-value ≤ 0.05 ผลการวิจัย: หลังออกกำลังกายแบบแอโรบิก ในสภาวะออกซิเจนต่ำความดันบรรยากาศปกติ พบว่าความจุปอดเต็มที่ (Vital Capacity: VC) ของ IT, SA และ IA มีปริมาตรเพิ่มขึ้นอย่างมีนัยสำคัญ และเมื่อวิเคราะห์ปริมาตรความจุหายใจเข้า (Inspiratory …

Inhibition Of Oxidative And Conjugative Metabolism Of Buprenorphine Using Generally Recognized As Safe (Gras) Compounds Or Components Of Dietary Supplements, Neha V. Maharao

Theses and Dissertations

This dissertation aimed at developing an inhibitor strategy to improve the oral bioavailability (F_oral) and systemic exposure (AUC_∞) of buprenorphine (BUP) as well as reduce the variability associated with them. Twenty-seven generally recognized as safe (GRAS) compounds or dietary substances were evaluated for their potential to inhibit the oxidative and conjugative metabolism of BUP, using pooled human intestinal and liver microsomes. In both the organs, oxidation appeared to be the major metabolic pathway with a 6 fold (intestine) and 4 fold (liver) higher intrinsic clearance than glucuronidation. Buprenorphine was predicted to show low and variable F …

We Still Need A Theory, Paula Droege

Animal Sentience

Woodruff (2017) has compiled a convincing array of data to support his contention that teleost fish feel pain. However, in the absence of an explanatory theory about the nature and function of consciousness, a checklist of criteria is insufficient to allay skeptical concerns. I offer a theory that can explain why features like selective attention and behavioral flexibility indicate consciousness. Consciousness represents the present moment in order to allow dynamic changes in actions or goals in response to situational demands.

Iraqi Refugees And Cultural Humility: A Mental Health Professional Training Program, Megan Brunmier Marsh

Antioch University Dissertations & Theses

This paper describes the development of a thorough nine-hour professional training program targeting the cultural humility of mental health clinicians who are treating new Iraqi refugee communities. I used the 15-step evidence-based Comprehensive Program Development Model created by Calley (2009) for the design of the structure, curriculum, and materials for this proposed program (Calley, 2011). The training program is informed by conceptual frameworks of cultural competence and humility, ecological systems theory, and social justice with goals of (a) exploring clinicians’ cultural attitudes in order to improve self-awareness at multiple levels (e.g., physiological, psychological, interpersonal), (b) increasing clinicians’ knowledge about Iraqi …

Employee Lived Experiences And Initiative Success In Arkansas Quality Award Recipient Organizations, Carol Barton

Walden Dissertations and Doctoral Studies

Businesses with failed quality initiatives lose revenue, experience high expenses, and have fewer market opportunities. Researchers attribute failed quality initiatives to human and social factors. The purpose of this phenomenological study was to explore the lived experiences of employees in companies that received an Arkansas Governor's Quality Award between 2010 and 2015. No one knows how employees' experiences contribute to successful quality initiatives, or how their stories about their experiences influence quality management and continuous improvement. The conceptual framework consisted of Weick's theory of sense-making and Deming's system of profound knowledge. Data were collected via semistructured interviews with 11 participants …

Wind Turbine Noise And Wind Speed Prediction, Tyler H. Blanchard

College of Graduate Studies: Theses & Dissertations

In order to meet the US Department of Energy projected target of 35% of US energy coming from wind by 2050, there is a strong need to study the management and development of wind turbine technology and its impact on human health, wildlife and environment. The prediction of wind turbine noise and its propagation is very critical to study the impacts of wind turbine noise for long term adoption and acceptance by neighboring communities. The prediction of wind speed is critical in the assessment of feasibility of a potential wind turbine site. This work presents a study on prediction of …

Puzzled Representations: Popular Media And How Educators Come To Know Autism, Vanessa N. Keener

College of Graduate Studies: Theses & Dissertations

People learn about the world through popular culture. Popular culture media representations of autism can be found in TV, film, literature, Internet media, advertisements, and more. This study employed a quantitative correlational design to survey 273 Georgia educators regarding their perceptions of autism, including knowledge about autism, best practices for teaching students labeled as having autism, perceived positivity and accuracy of popular media representations of autism, as well as participant identification with popular media representations of autism and personal characteristics (i.e., age, sex, level of education, type of degree, years of teaching experience, professional and personal experiences). Six major findings …

An Enhanced Spring-Particle Model For Red Blood Cell Structural Mechanics: Application To The Stomatocyte–Discocyte– Echinocyte Transformation, Mingzhu Chen, Fergal Boyle

Articles

Red blood cells (RBCs) are the most abundant cellular element suspended in blood. Together with the usual biconcave-shaped RBCs, i.e., discocytes, unusual-shaped RBCs are also observed under physiological and experimental conditions, e.g., stomatocytes and echinocytes. Stomatocytes and echinocytes are formed from discocytes and in addition can revert back to being discocytes; this shape change is known as the stomatocyte–discocyte–echinocyte (SDE) transformation. To-date, limited research has been conducted on the numerical prediction of the full SDE transformation. Spring- particle RBC (SP-RBC) models are commonly used to numerically predict RBC mechanics and rheology. However, these models are incapable of predicting the full …

Bulletin Of Yale University School Of Nursing 2017-2018, Yale School Of Nursing

Yale School of Nursing Bulletins and Catalogues

Series 113, Number 15

September 5, 2017

Chronicle & Character, Taryn Moller Nicoll

LSU Master's Theses

In this thesis paper, I argue that the works in the exhibition 'Chronicle & Character' aim to demonstrate artistic citizenship and can contribute positively to society by provoking conversation about universally applicable (but often uncomfortable) topics. Experts such as David J. Elliot state that being an artistic citizen means that one’s concerns as an artist must shift from issues constrained to the artist alone to those of the artist’s surrounding community. The exhibition 'Chronicle & Character' contains works that serve as detailed chronicles of the medical or physiological experiences of my loved ones. This body of work presents how three …

Examining The Hormonal Pleiotropy Hypothesis: Malayization Along An Elevational Gradient Can Be Associated With Behavioral, Hormonal And Immunological Differences In Lizards, Ryan Seddon

All-Inclusive List of Electronic Theses and Dissertations

Hormonal pleiotropy describes a suite of hormonally-linked traits. Such hormonal mediation may facilitate or constrain adaptive evolution of individual traits in the suite. Melanization, regulated in part by hormonal signals, can be tightly linked to non-color traits such as aggression, hormones, and immunity. While most studies examine within-population variation, I studied correlates of melanization, comparing both between- and within-population differences of adult male western fence lizards, Sceloporus occidentalis . I compared multiple high- and low-elevation populations in California, where populations are increasingly darker at higher elevations. I examined variation in 1) agonistic behavior of male lizards in response to staged …

The Effects Of Aerobic Exercise And Lipolytic Stimulation On Skeletal Muscle And Adipose Expression Of Perilipin 3 (Plin3) In Individuals With Type 2 Diabetes And Women With Polycystic Ovary Syndrome, Jeffrey Daniel Covington

LSU Doctoral Dissertations

Ectopic lipid accumulation in skeletal muscle is linked with insulin resistance and type 2 diabetes (T2D). Neutral lipid is stored as lipid droplets, which are coated by lipid droplet coat proteins. One important class of these proteins are the perilipins. Little research has focused on perilipin 3 (PLIN3) and coatomer gtp-ases, theorized to be involved in PLIN3 directed lipid oxidation. Under lipolytic stimulation with epinephrine or palmitate, forskolin, and ionomysin (PFI), primary human myotubes taken from health non-T2D donors showed increased protein content levels of PLIN3. Concordantly, following endurance exercise in non-T2D males—an experimental paradigm shown to increase lipolysis—levels of …