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Investigation Of Effects Of Fucoidan Polysaccharides Extracted From Twospecies Of Padina On The Wound-Healing Process In The Rat, Moazameh Kordjazi, Bahareh Shabanpour, Ebrahim Zabihi, Mohammad Ali Faramarzi, Hassan Ahmadi Gavlighi, Seyed Mohammad Amin Feghhi, Seyed Abbas Hosseini

Turkish Journal of Veterinary & Animal Sciences

Seaweeds contains different types of polysaccharides with high abilities. The aim of this study was to determine the potential of fucoidan polysaccharides for wound-healing properties. Fucoidans of two species of Padina (P. tetrastromatica and P. boergesenii), collected from the Persian Gulf northern coastal area, were extracted and analyzed using high-performance anion-exchange chromatography. Purified fucoidans were used to prepare a 2% topical ointment. Under aseptic conditions, two identical paravertebral full-thickness skin wounds (either by burn or excision) were made in 40 anesthetized male rats allocated into 4 groups. Either fucoidan ointments or the vehicle (ointment base) were applied to rats' wounds …

Field Investigation Of Trypanosoma Evansi And Comparative Analysisof Diagnostic Tests In Horses From Bahawalpur, Pakistan, Sonia Tehseen, Nusrat Jahan, Marc Desquesnes, Mirza Imran Shahzad, Muhammad Fiaz Qamar

Turkish Journal of Veterinary & Animal Sciences

In order to assess the prevalence of Trypanosoma evansi, a parasitological, molecular, and serological-based investigation was carried out in randomly sampled horses (n = 375) belonging to different age groups, sexes, and localities from the district of Bahawalpur, Pakistan. The diagnostic performance of applied tests was also compared. The prevalence was recorded as 0.5% with Woo's test, 1.3% with both ITS CF/BR PCR and RoTat 1.2 PCR, and 14.4% with CATT/T.evansi. Based on CATT/T.evansi, significant differences (P ≤ 0.05) were observed for prevalence estimates according to different localities, sexes, body condition scores, and origins. A nonsignificant difference (P ≥ 0.05) …

Comparison Of Four Ultrasonographic Approaches For The Diagnosis Ofacquired Reticular Diaphragmatic Hernia In Bovidae, Ashwani Kumar, Vandana Sangwan, Jitender Mohindroo, Narinder Singh Saini, Simrat Sagar Singh

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to look at four ultrasonographic approaches that diagnose acquired reticular diaphragmatic hernia (RDH) using either left or right caudal thoracic approaches (4th/5th intercostal space) and compare them to those made more cranially (1st/2nd intercostal space). Each sonographic observation was made in 27 unsedated, standing animals (22 buffaloes and 5 cattle) that were surgically confirmed for RDH. Using the right caudal thoracic approach, the herniated reticulum was seen as medial to the thoracic wall at a depth of 3-5 cm and adjacent to the cardiac silhouette. With the left caudal thoracic approach, the herniated reticulum …

Effects Of Ketamine On Monoamine Neurotransmittersand Gaba In Embryonic Neurocytes From Fetal Rat, Xinran Li, Mo Liu, Yue Li, Cen Guo, Lina Li, Yanan Li, Yuxin Wang, Yiming Zhang, Li Gao

Turkish Journal of Veterinary & Animal Sciences

The effect of ketamine, a drug commonly used as an anesthetic, on monoaminergic neurotransmitters and GABA in neurocytes from fetal rats has not yet been elucidated. We thus decided to investigate these effects by first evaluating ketamine levels in the cerebrospinal fluid by high-performance liquid chromatography. We thus determined the concentrations of GABA, DA, NE, 5-HT, and 5-HIAA following the addition of four different concentrations of ketamine at day 7 of nerve cell culture. GABA, 5-HT, and 5-HIAA levels were increased after an initial decrease: they showed the lowest levels at 10-15 min and the highest peaks at 45-90 min, …

Evidence Of Foot-And-Mouth Disease Virus Excretion In The Milk Ofapparently Healthy Vaccinated Buffaloes In Islamabad, Pakistan, Hafiziftikhar Ahmed, Umer Farooq, Aamer Bin Zahur, Khalid Naeem, Asma Latif, Hamid Irshad

Turkish Journal of Veterinary & Animal Sciences

The aim of the study was to determine the seroprevalence of foot-and-mouth disease (FMD) and isolation of the FMD virus (FMDV) in the milk of apparently healthy Asian buffaloes. A cross-sectional study was conducted in periurban dairy farms (n = 20) on ≥20 animals per farm in the suburbs of Islamabad, Pakistan. Sera samples (n = 200) were collected to monitor FMDV seroconversions. The analysis of serum samples using ELISA indicated a high seroprevalence of FMD (78%; 156/200) in Asian buffaloes. Milk samples were collected from FMDV seropositive animals only, and virus-specific signals were detected in 12.2% (19/156) of the …

Effects Of Season On Semen Parameters And Relationships Between Selected Semen Characteristics In Hypor Boars, Krzysztof Górski, Stanislaw Kondracki, Anna Wysokinska

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate the effect of the season of the year on the quality of Hypor boar semen and to determine the correlations between selected semen characteristics in particular seasons. Ejaculates from Hypor boars were analyzed for volume, sperm concentration, percentage of spermatozoa with normal motility, total number of spermatozoa, and the number of insemination doses per ejaculate. Microscopic slides were prepared from semen samples. Each sample was evaluated for the morphology of spermatozoa. Spermatozoa with normal morphology were counted, as well as those with both major and minor abnormalities. Spermatozoa were measured for morphometric …

Development Of Leptospiral Outer Membrane Protein-Based Dot-Elisa Assays And Immunoprofiling For Diagnosis Of Acute Canine Leptospirosis, Vamshi Krishna Sriram, Siju Joseph, Ambily Ramachandran, Mini Mangattumuruppel

Turkish Journal of Veterinary & Animal Sciences

The present study was carried out to evaluate outer membrane protein (OMP)-based relatively simple dot-ELISA assays for the diagnosis of acute canine leptospirosis and to identify the differential expression of leptospiral OMPs for identifying the markers of acute infection, if any. Among 91 canine serum samples screened, 63 samples were found to be positive by MAT. All the samples were tested by OMP-based IgM and IgG dot ELISAs. The sensitivities of IgM and IgG dot ELISA in comparison to MAT (titer: ≥1:400) were found to be 100%, whereas the specificities were found to be 89.71% and 45.31%, respectively. IgM and …

Effect Of Dosage And Duration Of Altrenogest Treatmenton Follicular Development And Ovulation In Sows*, Supatee Kitkha, Alongkot Boonsoongnern, Nattavut Ratanavanichrojn, Pichai Jirawattanapong, Anuchai Pinyopummin

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to investigate the effect of altrenogest (ALT) treatment on follicular development and ovulation in sows. Sows (parity 6-9; D0: weaning day) were assigned to four treatments as follows: control (no ALT treatment; n = 20), ALT-4-0 (ALT 20 mg/day, 5 days; D-4-D0; n = 20), ALT-4-2 (ALT 20 mg/day, 7 days; D-4-D2; n = 23), and 2ALT-4-2 (ALT 20 mg twice a day [40 mg/day], 7 days; D-4-D2; n = 24). The sows in each group were further divided into three groups based on slaughter periods: day 1 (DF1) and day 4 (DF4) of …

Extraskeletal Chondroblastic Osteosarcoma Of The Subcutaneous Tissue In A Maltese Dog, Byungjoon Seung, Junghyung Ju, Seunghee Cho, Soohyeon Kim, Hwan Choi, Junghyang Sur

Turkish Journal of Veterinary & Animal Sciences

A 10-year-old spayed female Maltese dog presented to a local animal hospital with a subcutaneous mass (4 x 3 x 3 cm) in the right shoulder region. The mass was well circumscribed, with soft tissue opacity and variable levels of mineralization, but with no bony involvement in radiography. The mass was surgically removed. Upon histological examination, the mass consisted of malignant mesenchymal cells that had produced a chondroid matrix and osteoid. Round to polygonal neoplastic cells with large nuclei showed moderate anisokaryosis and variable numbers of mitotic figures. The tumor cells were positive for vimentin and osteocalcin and negative for …

Doxorubicin Kinetics And Effects On Lung Cancer Cell Lines Using In-Vitro Raman Micro-Spectroscopy: Binding Signatures, Drug Resistance And Dna Repair, Hugh Byrne, Franck Bonnier, Alan Casey, Orla L. Howe, Zeineb Farhane

Articles

Raman micro-spectroscopy is a non-invasive analytical tool, whose potential in cellular analysis and monitoring drug mechanisms of action has already been demonstrated, and which can potentially be used in pre-clinical and clinical applications for the prediction of chemotherapeutic efficacy. To further investigate such potential clinical application, it is important to demonstrate its capability to differentiate drug mechanisms of action and cellular resistances. Using the example of Doxorubicin (DOX), in this study, it was used to probe the cellular uptake, signatures of chemical binding and subsequent cellular responses, of the chemotherapeutic drug in two lung cancer cell lines, A549 and Calu-1. …

Vibrational Spectroscopy As A Tool For Studying Drug-Cell Interaction: Could High Throughput Vibrational Spectroscopic Screening Improve Drug Development, Lauren E. Jamieson, Hugh Byrne

Articles

Vibrational spectroscopy is currently widely explored as a tool in biomedical applications. An area at the forefront of this field is the use of vibrational spectroscopy for disease diagnosis, ultimately aiming towards spectral pathology. However, while this field shows promising results, moving this technique into the clinic faces the challenges of widespread clinical trials and legislative approval. While spectral pathology has received a lot of attention, there are many other biomedical applications of vibrational spectroscopy, which could potentially be translated to applications with greater ease. A particularly promising application is the use of vibrational spectroscopic techniques to study the interaction …

Prediction Of Viral Loads For Diagnosis Of Hepatitis C Infection In Human Plasma Samples Using Raman Spectroscopy Coupled With Partial Least Squares Regression Analysis, Hugh Byrne, Franck Bonnier, H. Nawaz, N. Rashid, M. Saleem

Articles

Raman spectroscopy has been used to identify the biochemical changes associated with the presence of the Hepatitis C virus (HCV) in infected human blood plasma samples as compared with healthy samples, as control. The aim of the study was to establish the Raman spectral markers of hepatitis infection, which could be used for diagnostic purposes. Moreover, multivariate data analysis techniques, including Principal Component Analysis (PCA), coupled with Linear Discriminant Analysis (LDA), and Partial Least Square Regression (PLSR) are employed to further demonstrate the diagnostic capability of the technique. The PLSR model is developed to predict the viral loads of the …

Determination Of Spectral Markers Of Cytotoxicity And Genotoxicity Using In Vitro Raman Microspectroscopy: Cellular Responses To Polyamidoamine Dendrimer Exposure, Esen Efeoglu, Alan Casey, Hugh Byrne

Articles

Although consumer exposure to nanomaterials is ever increasing, with potential increased applications in areas such as drug and/or gene delivery, contrast agents and diagnosis, determination of cyto- and geno- toxic effect of nanomaterials on human health and the environment still remains challenging. Although many techniques have been established and adapted to determine the cytotoxicity and genotoxicity of nano-sized materials, these techniques remain limited by the number of assays required, total cost, use of labels and they struggle to explain the underlying interaction mechanisms. In this study, Raman microspectroscopy is employed as an in vitro label free high content screening technique …

Comparison Of Various Technologies In The Acquisition Of Speech Samples For Transcription Purposes: Listener Perception Vs. Acoustic Analysis Of Signal Quality, Alexa Klimes

Honors Program Theses

The purpose of this study was to investigate the quality of recordings obtained with a dedicated recording device in comparison to more readily available devices. Professionals in the field of communication disorders need to identify and transcribe specific details about individuals’ speech and need high quality recordings for this purpose (Louko & Edwards, 2001). The dedicated recording devices that provide high quality signals are not readily available and can be expensive. The available research on this topic focuses on analysis of voice characteristics such as fundamental frequency, amplitude, and stability of amplitude and frequency (Lin, Hornibrook, & Ormond, 2012; Vogel …

A Presidential Paradigm Shift: Changes In Presidential Rhetoric Regarding Cuba, Alyssa Chellan Dixon

Honors Program Theses

On March 22, 2016, United States President Obama and Cuban President Raúl Castro sat side-by-side in the Estadio Latinoamericano baseball stadium, watching the Tampa Bay Rays and the Cuban national team face off in a historic game. Such an event would have been unprecedented in the several decades prior to its occurrence. Indeed, though at the U.S.-Cuba game Obama and Raúl Castro were even as friendly to have participated in doing “the wave” together,ii relations between the U.S. and Cuban governments were anything but, even during the preceding U.S. presidency of George W. Bush.

The United States has had a …

Utilisation Des Prothèses Auditives En Milieu De Travail Bruyant, Tony Leroux, Chantal Laroche, Christian Giguère, Jérémie Voix

Rapports de recherche scientifique

Le bruit est encore très présent en milieu de travail. Plusieurs travailleurs vivent donc quotidiennement avec une surdité professionnelle. D’autres peuvent par ailleurs présenter une surdité d’origine non professionnelle et enfin, la population active vieillissante présente plus de risques de souffrir d’une perte auditive. Une surdité peut compromettre la réalisation efficace des tâches et la sécurité du travailleur et celle d’autrui lorsqu’elle est accompagnée de difficultés à percevoir des signaux sonores, à comprendre la parole en présence de bruit et à bien localiser la provenance des sons dans l’espace. Afin de maintenir une juste perception de l’environnement sonore …

Inside The Black Box: Political Economy Of The Trans-Pacific Partnership's Encryption Clause, Han-Wei Liu

Research Collection Yong Pung How School Of Law

Among other provisions of the Trans-Pacific Partnership (TPP) Agreement, a new clause on encryption technology (‘Encryption Clause’) is particularly noteworthy. By tracing the history of decades-long encryption control, this article underscores how this clause implicates international order. Modern encryption technology was conceived and developed during World Wars. Painted by such a war-time legacy, encryption has been treated as a ‘dual-use’ technology and has been subject to export control since the end of World War II via the Coordinating Committee for the Control of Multinational Trade (COCOM) and, later, the Wassenaar Arrangement. With the collapse of the Soviet Union, the Western …

The Legality Of Data Residency Requirements: How Can The Trans-Pacific Partnership Help?, Shin-Yi Peng, Han-Wei Liu

Research Collection Yong Pung How School Of Law

Article 14.13 of the Trans-Pacific Partnership (TPP) Agreement – the data localization (DL) clause – represents the first time that a far-reaching preferential trade agreement (PTA) seeks to reduce protectionism arising from data residency (DR) requirements. The DL clause, however, is linked to a loose GATT Article XX-like exception: Article 14.13(3)(b), which allows the parties to maintain DR measures to achieve a legitimate public policy objective as long as the measure in question can satisfy the ‘necessity test’. The ambiguity of the DL exception will be clarified by TPP tribunals when a real dispute occurs. After examining the rationales of …

White Paper Of Democratic Criminal Justice, Joshua Kleinfeld, Laura I. Appleman, Richard A. Bierschbach, Kenworthey Bilz, Josh Bowers, John Braithwaite, Robert P. Burns, R. A. Duff, Albert W. Dzur, Thomas F. Geraghty, Adriaan Lanni, Marah Stith Mcleod, Janice Nadler, Anthony O'Rourke, Paul H. Robinson, Jonathan Simon, Jocelyn Simonson, Tom R. Tyler, Ekow N. Yankah

Journal Articles

This white paper is the joint product of nineteen professors of criminal law and procedure who share a common conviction: that the path toward a more just, effective, and reasonable criminal system in the United States is to democratize American criminal justice. In the name of the movement to democratize criminal justice, we herein set forth thirty proposals for democratic criminal justice reform.

Criminal Trademark Enforcement And The Problem Of Inevitable Creep, Mark P. Mckenna

Journal Articles

This Article, delivered as the 2017 Oldham Lecture at the University of Akron School of Law, focuses on the federal Trademark Counterfeiting Act (TCA), the primary source of federal criminal trademark sanctions. That statute was intended to increase the penalties associated with the most egregious form of trademark infringement — use of an identical mark for goods identical to those for which the mark is registered and in a context in which the use is likely to deceive consumers about the actual source of the counterfeiter’s goods. The TCA was intended to ratchet up the penalties associated with counterfeiting, but …

Evidence And Innovation In Housing Law And Policy, Lee Anne Fennell, Benjamin J. Keys

Books

No abstract provided.

Adultery: Trust And Children, Margaret F. Brinig

Journal Articles

Deborah Rhode writes that while adultery is admittedly not good, it should not be criminal. She argues that it should not generate a tort action either, because the original purposes for which the torts of alienation of affections and criminal conversation come from a time with quite different views about marriage and gender, while no-fault and speedy divorce today give adequate remedies to the wronged spouse. Further, adultery should not affect employment (as a politician or in the military) unless it directly impacts job performance.

My own reluctance to disengage adultery and law stems from the seriousness of adultery. First, …

Truth And Politics: A Symposium On Peter Simpson's Political Illiberalism: A Defense Of Freedom., Gerard V. Bradley

Journal Articles

There is no more important question in thinking about life-and actually living-in political community than whether it is to be permeated by, and purposefully oriented around, the main truths about human flourishing. It is at least paradoxical that, precisely when the state and its law and political life are shaping people's lives more and more, the professed roots of all this influence are growing thinner, more shallow. Lawmakers who profess and in many cases even think they should be "neutral" about values are more involved with how persons' lives go than, perhaps, ever before.

Of course, any community which has …

The Statewide Standard, 2017, College Of Education

The Statewide Standard

No abstract provided.

From A Muddle To A Mudslide: Murr V. Wisconsin, Nicole Stelle Garnett

Journal Articles

This article analyzes the U.S. Supreme Court's most-recent regulatory takings decision, Murr v. Wisconsin, concluding that the decision further muddies the takings waters and threatens to undermine the already-limited protection of private property provided by the Fifth Amendment's Takings Clause.

Countering The Majoritarian Difficulty, Amy Coney Barrett

Journal Articles

In Our Republican Constitution, Randy Barnett argues that the United States Constitution rests on a foundation of individual rather than collective popular sovereignty. Grounding the legitimacy of the government in the authority given it by each individual rather than by the People as a whole echoes the thesis, advanced in Barnett’s prior work, that the government must justify incursions upon individual liberty. If the People as a body are sovereign and the Constitution is designed to facilitate democratic self-governance, legislation is presumptively legitimate because it represents the sovereign will of the democratic majority. If the individual is sovereign, by contrast, …

Interleukin (Il)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation And Diminishes Circulating Il-18., Robert Z. Harms, Austin J. Creer, Kristina M. Lorenzo-Arteaga, Katie R. Ostlund, Nora Sarvetnick

Journal Articles: Surgery

The cytokine interleukin (IL)-18 is a crucial amplifier of natural killer (NK) cell function. IL-18 signaling is regulated by the inhibitory effects of IL-18 binding protein (IL-18BP). Using mice deficient in IL-18BP (IL-18BPKO), we investigated the impact of mismanaged IL-18 signaling on NK cells. We found an overall reduced abundance of splenic NK cells in the absence of IL-18BP. Closer examination of NK cell subsets in spleen and bone marrow using CD27 and CD11b expression revealed that immature NK cells were increased in abundance, while the mature population of NK cells was reduced. Also, NK cells were polarized to greater …

Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging Of Antiretroviral Drug Particle Tissue-Cell Biodistribution, Bhavesh D. Kevadiya, Christopher J. Woldstad, Brendan M. Ottemann, Prasanta Dash, Balasrinivasa R. Sajja, Benjamin G. Lamberty, Brenda M. Morsey, Ted Kocher, Rinku Dutta, Aditya N. Bade, Yutong Liu, Shannon E. Callen, Howard S. Fox, Siddappa N. Byrareddy, Joellyn M. Mcmillan, Tatiana K. Bronich, Benson J. Edagwa, Michael D. Boska, Howard Gendelman

Journal Articles: Radiology

RATIONALE: Long-acting slow effective release antiretroviral therapy (LASER ART) was developed to improve patient regimen adherence, prevent new infections, and facilitate drug delivery to human immunodeficiency virus cell and tissue reservoirs. In an effort to facilitate LASER ART development, “multimodal imaging theranostic nanoprobes” were created. These allow combined bioimaging, drug pharmacokinetics and tissue biodistribution tests in animal models.

METHODS: Europium (Eu³⁺)- doped cobalt ferrite (CF) dolutegravir (DTG)- loaded (EuCF-DTG) nanoparticles were synthesized then fully characterized based on their size, shape and stability. These were then used as platforms for nanoformulated drug biodistribution.

RESULTS: Folic acid (FA) decoration of …

Personal Health Behaviors And Health Counseling Practices Of Professional Psychologists And Trainees Across Setting And Population Types, Alexa Barnett

Theses and Dissertations

This study examined the health behaviors and health counseling practices among psychologists and psychology trainees, focusing on a variety of settings of practice. Both psychologists and trainees self-reported practicing a greater number of health enhancing behaviors compared to equivalent U.S. adults. Results indicated a higher rate of health counseling activity when psychologists and trainees endorsed counseling on health behaviors as more important, and additionally when having more training in health counseling. The results of this study expand upon the growing literature related to health professionals’ personal health behaviors and focuses on population health needs for improved health behaviors. Future research …

Relationships Among Health Counseling Training Experiences And Time Engaged In Counseling, Percentage Of Patients Counseled, Practitioner Confidence, And Perceived Importance, Stephen Edward Lupe

Theses and Dissertations

In the current healthcare system, the need for collaborative care is higher than ever. With current reforms in reimbursement and healthcare policies, it is becoming increasingly necessary for psychologists and other practitioners to break ranks with their traditional roles and to participate as a part of a multidisciplinary team that works in collaboration with other healthcare professionals. This study aims to look at the health counseling behaviors of psychologists and graduate psychology students from an APA accredited clinical psychology graduate program. It aims to examine the relationships among health counseling training variables and time spent engaging in health counseling, highest …