Digital Commons Network^™

The Anticancer Effects Of The Different Analogs Of Cysteine Deleted Tachyplesin On A549 Lung Cancer Cells, Nathan Riley Hendrickson

Master's Theses and Doctoral Dissertations

It has been previously shown that cysteine-deleted tachyplesin (CDT) and its many analogs display antibacterial effects. However, little has been said about its possible anticancer effects and which analogs serve as the best inhibitors of the growing cancer cells. This research focused on CDT and four of its analogs: All D-CDT, Reverse DCDT, Reverse CDT, and Serine-Control CDT. MTT assays against the A549 adenocarcinoma lung cancer cell line showed All D-CDT to be the most effective analog in preventing cancer cell growth. Hyaluronidase and apoptosis assays were performed to better understand the mechanism by which the All D-CDT is preventing …

Contributors To Processing Speed Deficit In Old Age: A Focus On History Of Obesity And Medical Conditions, Melissa E. Pulcini

Master's Theses and Doctoral Dissertations

Obesity has been associated with impairment in most cognitive domains, but the nature of this relationship is unclear. Most studies have examined the relationship between cognitive impairment and current obesity and/or history of obesity-related medical conditions. However, a number of “lower-level” obesity factors (e.g., increased adipokines, low grade inflammation, chronic mild hypoventilation) are present even among the otherwise healthy obese population, and it is possible that many of these factors have differential impact on cognition according to magnitude and duration of exposure. Knowledge of a person’s weight history, which may serve as a proxy for a number of lower-level obesity …

Searching The Scriptures: Andrews University Seminary Emerging Scholars Pay Tribute To Their Professors, Slavisa Milodar Jankovic

All Books

The purpose of this project is simple. In writing these essays each author wishes to offer a tangible expression of appreciation and gratitude to those professors who have invested their time in teaching them the value of studying Scripture. Each one of the professors represented has greatly influenced the authors’ understanding of the Biblical text, and for this they are forever indebted to them. This festschrift recognizes the scholarship of the following professors: Drs. Richard M. Davidson, Jiří Moskala, Roy Gane, Ranko Stefanović, Paul Gregor, and Thomas Shepherd.

The Long Journey Of Joshua Louis Hicks: A Voice From The Texas Working Class, Kyle Wilkison

East Texas Historical Journal

No abstract provided.

Ethj Vol-55 No-2

East Texas Historical Journal

No abstract provided.

The Mental Health Benefits Of Having Dogs On College Campuses, Trenton Adams, Catherine Clark, Victoria Crowell, Kolleen Duffy, Margaret Green, Selena Mcewen, Allison Wrape, Frank Hammonds

Modern Psychological Studies

College can be a stressful time for many, especially those dealing with problems like stress, anxiety, and depression. While colleges and universities typically offer counseling services, many students who could benefit do not take advantage of them. Research suggests that animals may play an important role in some forms of treatment for conditions such as anxiety, stress, and depression. A recent trend on college campuses is to offer opportunities to interact with dogs and other animals as a way to relieve stress and help individuals deal with other psychological issues. In this paper, we discuss the current research regarding using …

"To Be Novelized": An Investigation Of Autofiction & How It Operates In Gwenaelle Aubry's No One, Ava Dean

University Honors Theses

This thesis seeks to identify and understand the neologism "autofiction" through literary theory and the employment of this genre in Gwenaelle Aubry's No One.

Exploring The Function Of Exon 7 In Drosophila Cacophony In Relation To Als, Jasmine E. Ahrar

University Honors Theses

Defects in the TAR DNA-binding protein named TDP-43 are known to be involved with many neurodegenerative diseases, including ALS. TBPH, a TDP-43 Drosophila orthologue is used to explore the specifics of those defects. This protein is known to have many cellular roles, one of them being a regulator for splicing. TBPH null flies have shown that the region coding for the voltage gated calcium channel cacophony is a potential target for splicing, directly producing a greater number of transcripts that lack exon 7. In this report, the phenotype of adult flies that lack exon 7 is explored. These mutants are …

A Biological Comparison Of Two Sites: An Ecological Approach Using Community Ecology Metrics Based On Insect Faunal Composition, Kennedy J. Martin

University Honors Theses

Two natural sites in the Portland urban area, River View Natural Area (RVNA) and Powers Marine Park (PMP), were sampled to assess their insect faunal composition with the intention of determining whether the areas are sufficiently similar ecologically that they could potentially be managed as a single unit. The two areas were compared using community ecology metrics based on their respective invertebrate fauna. The results suggested that RVNA and PMP had statistically different ecological communities. The Shannon Diversity Index for PMP was 0.303, and 0.819 for RVNA. The Horn Index of Community Overlap suggested a 93.46% overlap based on these …

Using Cultural Relevancy To Promote African American Brain Health, Miya Walker

University Honors Theses

African Americans are disproportionately more likely than older whites to develop Alzheimer’s disease and other dementias (ADOD). Despite these disparities, there is difficulty in motivating African Americans to engage in activities suitable to maintaining cognitive health (walking, social engagement, physical activity). The Sharing History through Active Reminiscence and Photo-imagery (SHARP) walking program (Croff, PI) combines these proactive activities in a culturally relevant way to create a motivational force to preserve cognitive health. SHARP engaged 19 African Americans aged 55 and older on 72 themed, 1-mile walks over 6 months in Portland, Oregon’s historically Black neighborhoods. This study examines participant responses …

Making Makeup: A Recipe Book For All-Natural Cosmetics, Jessica Arlich

University Honors Theses

In the past five years, there has been increasing demand for organic consumables in the United States every year by mainstream culture. Also, with the prevalence of the Internet, people can find resources to make almost anything. Do-it-yourself culture is huge. The marriage of these two facts allowed me to explore my thesis topic.

The goal of my thesis project was to create a book of recipes for all-natural cosmetics, similar to a cookbook. I engaged in lots of research and experimentation to create my own recipes. I used modern layout with a humanist typeface and brush-script to emphasize the …

How Does The 12-Step Model Of Recovery Benefit And Complicate Harm Reduction Strategies For Substance Abusing Adolescent Youth?, Matthew Matteini

University Honors Theses

Alongside harm reduction strategies, the abstinence-based 12-step model of recovery has become an increasingly prominent means of addressing substance abuse among American adolescent youth. These two different models of recovery are commonly being implemented in tandem with one another as a means of treating substance abuse for adolescent youth. Despite the common occurrence of dual implementation, there has been limited research into the impact these modalities have upon one another. Using a narrative review, this study utilizes existing literature to highlight key means through which the 12-step model of recovery works as both an asset and a hindrance to harm …

Aerobic And Anaerobic Exercise: Analyzing The Benefits Of Different Forms Of Exercise For Adults Diagnosed With Type 2 Diabetes, Mark A. Yakubovich

University Honors Theses

This paper explores multiple published articles that will consider the effects of aerobic and anaerobic exercise performed by adult individuals diagnosed with type 2 diabetes mellitus. It will also explore the benefits of combining both forms of exercise and how each compare in terms of glycemic control. This paper will specifically be looking at the benefits of exercise on type 2 diabetes mellitus. I acknowledge that a combination of both exercise and nutrition is optimal for individuals with type 2 diabetes, but this paper is solely looking at the effects of exercise. I will be analyzing the methods used in …

Implications Of Psychotherapy And Low-Dose Medication Following First-Episode Psychosis, Alyssa Woolley

University Honors Theses

Schizophrenia, a mental disorder characterized by hallucinations, delusions, and disorganized thoughts and speech, is typically treated using antipsychotic medication and therapy. Randomized trials focusing on schizophrenia have provided evidence that early intervention, which entails talk therapy combined with low-dose antipsychotic medication directly following onset of psychosis, is most effective in treating symptoms. The literature review detailed in this paper is intended to help better understand the relationship between low-dosage antipsychotic medication, pair with regular psychotherapy, and how that relationship can help patients to adhere to treatment for long-term remission.

Lacking Legitimacy: Neoliberal Governance And The Erosion Of Local Democracy In The United States And Argentina, Adriane Ackerman

University Honors Theses

An extension of capitalism’s relentless growth, neoliberal globalization has characterized most of the policies and practices that have proliferated between nation-states since the late 1970's, producing a "flatter" world in which spheres of influence, both economically and politically, have become inextricably interdependent. Some prominent results of this interdependence include consolidation of wealth, extreme socioeconomic stratification, greater influence of money upon politics, and deepening ideological divide within the populace. Increased sharing of the roles and responsibilities of governing with the private sector, along with increased access to information and exposure to systemic nepotism, have together undermined the sovereignty and preeminence of …

Language In The Korean Workplace: An Analysis Of Hierarchical Language Use In The Drama Misaeng, Jessie Nicole Mcneill

University Honors Theses

The influences of Confucian and neo-Confucian values can be seen in contemporary Korean culture and language (Seth 2016). The Korean language is hierarchical, meaning that the language demonstrates a clear social hierarchy between speakers through the use of various determined linguistic techniques (Agha 1998). Native Korean speakers employ a combination of speech styles and levels, honorifics, politeness and humbling strategies to convey their reception of the hearer’s social location in the hierarchy (Choo 2006). The environment of the Korean workplace is shaped by these cultural values with very apparent social stratification by rank (Lee 2012). The emphasis on social stratification …

Women And The Wilderness: A Review Of Barriers To Participation, Current Coping Strategies, And Guidance For Future Programs, Naiyear Khajavei

University Honors Theses

This literature review discusses the obstacles that women face in participating in outdoor recreation, the ways in which they are currently navigating these obstacles, and discusses how the currently literature (and the gaps within it) can inform our future research and policy making. The obstacles women currently face in wilderness recreation surround gender roles and social expectations, lack of early skill-development and confidence, and a gendered geographic fear. Currently, women are navigating these obstacles by either conforming or rejecting gender roles in their participation, choosing to develop skills in female-only environments, and taking means to increase perceived safety such as …

The Role Of Divalent Metals In Dna Replication During Periods Of Oxidative Stress, Corinne Hutfilz

University Honors Theses

Reactive oxygen species (ROS) are generated through regular aerobic metabolism and iron-catalyzed degradation of hydrogen peroxide (Fridovich, 1995). ROS are known to induce single strand breaks (SSBs) in DNA via sugar or base modification (Lindahl, 1993), and double strand breaks (DSBs) can also occur when the replicative polymerase complex (replisome) polymerizes over oxidative lesions (Andrews et al., 2003), or when clustered oxidative lesions are misrepaired (Semenenko and Stewart, 2005; Semenenko et al., 2005). Intracellular ROS production has also been shown to increase after UV-induced and endogenous DNA damage (Rowe et al., 2008). All DNA lesions must be repaired for the …

Associations Between Willingness To Exert Cognitive Effort And Smoking Abstinence, Austin A. Phanouvong, Darby K. Dyar, Suzanne H. Mitchell

University Honors Theses

In decision-making tasks, individuals who prefer smaller, immediate rewards over larger, delayed rewards (delay discounting) are less likely to quit smoking. Indeed, decision-making tasks with delayed reward costs are sensitive to many aspects of substance use disorders. However, other reward costs might also be important. Our study focused on one of these other reward costs, which was cognitive effort (CE). 22 current smokers who were anticipating quitting in the near future were recruited to validate if more CE discounting predicted shorter abstinence times in reinforced smoking lapse period. Each participant had to be aged 18-45, and smoke 10-20 cigarettes daily. …

From Stem To Steam: The Neuroscience Behind The Movement Towards Arts Integration In K-12 Curricula, Kayla G. Townsley

University Honors Theses

As a result of disparities in the educational system, numerous scholars and educators across disciplines currently support the STEAM (Science, Technology, Engineering, Art, and Mathematics) movement for arts integration. An educational approach to learning focusing on guiding student inquiry, dialogue, and critical thinking through interdisciplinary instruction, STEAM values both the proficiency of knowledge and understanding. Despite extant literature urging for this integration, the trend has yet to significantly influence federal or state standards for K-12 education in the United States.

This paper provides a brief and focused review of key theories and research from the fields of cognitive …

Microfinance: The Impacts Of A Poverty Reduction Approach And Financial Systems Approach On Poor Rural Households In Vietnam, Cardin A. Le

University Honors Theses

The microfinance industry has evolved from its earliest roots as a social movement to a multifaceted financial services industry for the poor. The aim of this research is to add to the existing literature by exploring the poverty reduction approach and financial systems approach to microfinance and its implications on poor rural households in Vietnam. It does this through analyzing three main areas: (i) a comprehensive assessment of microfinance in Vietnam; (ii) analyzing the advantages and disadvantages of the poverty reduction and financial system approaches; and (iii) evaluating the impact of access to credit on household poverty reduction in rural …

A Novel Approach To Assessing The Quality Of Coach-Athlete Relationships: Can The Coach-Athlete Relationship Be Evaluated For Motivational Support By Analysis Of Published Coach Interviews?, Nikia C. Evans

University Honors Theses

The aim of this paper is to present a novel methodology to be used in evaluating the quality of the coach-athlete relationship in line self-determination theory and based on the motivational model of the coach-athlete relationship proposed by Mageau and Vallerand. This paper consists of a review of the extant literature surrounding self-determination theory as applied to sports, followed by a pilot study testing the proposed new methodology. The methodology utilizes existing coach interviews conducted by institution media to evaluate the language used by NCAA D1 soccer coaches in reference to their teams. The findings of the study serve to …

Patient, Victim, Or Survivor?: An Analysis Of Sane Nursing Curriculum Bias, Samantha D. Gardner

University Honors Theses

This study assesses the SANE program training for the Oregon Sexual Assault Task Force to identify gaps that fail to address bias, causing SANE nurses to provide less-effective care to people who have experienced interpersonal violence. This thesis will address a particular question: How does the SANE nursing curriculum address bias? When reviewing the literature, it is clear that both biases and gaps in SANE training negatively affect survivors experiences. In order to address both biases and gaps, I conducted an initial read read-through of the curriculum text. Next, I made memos on notecards of the key words, phrases, and …

Innovator Or Butcher?: Herophilean Research Methods In Early Ptolemaic Alexandria, Annastasia C. Conner

University Honors Theses

In a period of Ptolemaic Alexandria that has been referred to by modern scholars as a "frontier environment" for scientific achievement and discoveries, Herophilus of Chalcedon was a leader of innovation. Religious and cultural boundaries and the presence of taboos and death-based pollution should perhaps have limited his research capabilities, but under the patronage of the ruling Ptolemaic kings (Ptolemy I Soter, and Ptolemy II Philadelphus both reigned during Herophilus' lifetime), he and his contemporaries were able to dissect and vivisect human cadavers within the pursuit of their studies. Although Herophilus' therapeutic practices largely fell within the scope of the …

The Choctaw Nation Of Oklahoma: History, Influences, And Contemporary Setting Of The Choctaw Legal Structure, Austin C. Megli

Tribal Law Journal

The goal of this tribal profile is to provide an overview of the internal laws of the Choctaw Nation of Oklahoma; to give a detailed emphasis on the tribe’s historic use of customary law, governance structures, enacted law, case law; and to examine how their internal law changed throughout history. By helping the reader become familiar with the history of Choctaw customary law and the contemporary structure of the Choctaw government, this profile will assist practitioners and academics in understanding the Choctaw Nation. Part I of this paper will describe the customary laws of the Choctaw Nation. Part II of …

If Trees Could Lobby They Would Be People Too: The Environmental And Cultural Benefits Of Granting Legal Personality To Nature, M. Alexis Volner

Tribal Law Journal

In the Western culture today, the environment is perceived as a source for goods and resources. However, this perspective has resulted in serious environmental degradation and a real threat to our species’ survival. To combat these problems there must be a radical shift in the Western culture’s conception of nature.

The first step in this shift is to recognize the environment as a legal person. The United States should grant legal personality to all publicly owned lands containing sites held sacred by Indigenous peoples and establish a collaborative board to manage the sites to recognize Indigenous cultural rights and encourage …

Engaging Parents To Promote Children’S Nutrition And Health: Providers’ Barriers And Strategies In Head Start And Child Care Centers, Dipti A. Dev, Courtney Byrd-Williams, Samantha Ramsay, Brent A. Mcbride, Deepa Srivastava, Ashleigh L. Murriel, Chrisa Arcan, Anna M. Adachi-Mejia

Department of Child, Youth, and Family Studies: Faculty Publications

Purpose: Using the Academy of Nutrition and Dietetics benchmarks as a framework, this study examined childcare providers’ (Head Start [HS], Child and Adult Care Food Program [CACFP] funded, and non-CACFP) perspectives regarding communicating with parents about nutrition to promote children’s health.

Design: Qualitative.

Setting: State-licensed center-based childcare programs.

Participants: Full-time childcare providers (n ¼ 18) caring for children 2 to 5 years old from varying childcare contexts (HS, CACFP funded, and non-CACFP), race, education, and years of experience.

Methods: In-person interviews using semi-structured interview protocol until saturation were achieved. Thematic analysis was conducted.

Results: Two overarching themes were barriers and …

Role Of Food Preoccupation And Current Dieting In The Associations Of Parental Feeding Practices To Emotional Eating In Young Adults: A Moderated Mediation Study, Natalie A. Williams, Dipti A. Dev, Maren Hankey, Kimberly A. Blitch

Department of Child, Youth, and Family Studies: Faculty Publications

Parental feeding practices reflecting coercive control are related to children’s later eating behaviors, but the mechanisms underlying these effects remain poorly understood. This study examined the relationships between recalled childhood experiences of parental pressure to eat and restriction and current food preoccupation, dieting, and emotional eating in a racially diverse sample of college students (N = 711). Results revealed that parental restriction, but not pressure to eat, was associated with more emotional eating (r = 0.18, p < 0.0001). Food preoccupation mediated the association between restriction and emotional eating (95% CI [3.6495–7.2231]); however, a moderated mediation model revealed that the strength of the indirect effect of restrictive feeding on emotional eating through food preoccupation was significantly different for dieters and non-dieters (index of moderated mediation = 1.79, Boot SE = 0.79; 95% bias-corrected bootstrap CI [–3.5490 to –0.4515]). These findings provide unique insight into the mechanisms linking parental feeding practices with emotional eating in young adulthood. Future studies attempting to clarify the processes through which child feeding practices impact later eating behaviors should consider the role of current dieting.

Implementing The Academy Of Nutrition And Dietetics Benchmarks For Nutrition Education For Children: Child-Care Providers’ Perspectives, Dipti A. Dev, Virginia Carraway-Stage, Daniel J. Schober, Brent A. Mcbride, Car Mun Kok, Samantha Ramsay

Department of Child, Youth, and Family Studies: Faculty Publications

Background — National childhood obesity prevention policies recommend that childcare providers educate young children about nutrition to improve their nutrition knowledge and eating habits. Yet, the provision of nutrition education (NE) to children in child-care settings is limited.

Objective — Using the 2011 Academy of Nutrition and Dietetics benchmarks for NE in child care as a guiding framework, researchers assessed child-care providers’ perspectives regarding delivery of NE through books, posters, mealtime conversations, handson learning, and sensory exploration of foods to young children (aged 2 to 5 years).

Design — Using a qualitative design (realist method), individual, semistructured interviews were conducted …

Patterns Of Psychotropic Medication At Admission For Youth In Residential Care, Jonathan C. Huefner, Gail L. Smith, Jay L. Ringle, Amy L. Stevens, W. Alex Mason, Gilbert R. Parra

Department of Child, Youth, and Family Studies: Faculty Publications

High levels of psychotropic medication use and polypharmacy are common for emotionally and behaviorally troubled youth entering residential care. Polypharmacy has often been characterized as an especially serious problem in this vulnerable population. Latent Class Analysis was used to identify medication subgroups for 636 youth in an intensive residential program. Additionally, auxiliary analyses (e.g., diagnoses, demographics, expressed problem behaviors) were used to identify the personal and behavioral attributes associated with individuals in each of the latent classes. Three distinct medication patterns emerged: low/no psychotropic medication, the combination of antidepressant and antipsychotic medications, and multiple psychotropic medications. The latent classes were …