Digital Commons Network^™

Association Of Pathogenic/Likely Pathogenic Inherited Cardiomyopathy Variants With Heart Failure: A Topmed Multiancestry Analysis, Naman S Shetty, Mokshad Gaonkar, Akhil Pampana, Nirav Patel, April P Carson, Bernhard Haring, Bruce M Psaty, Charles Kooperberg, Eric Boerwinkle, Jerome I Rotter, João A C Lima, Jorge R Kizer, Lisa Warsinger Martin, Kent D Taylor, Michael E Hall, Myriam Fornage, Sanjiv J Shah, Stephen S Rich, Ramachandran S Vasan, Rami Nassir, Peng Li, Garima Arora, Pankaj Arora

Faculty, Staff and Student Publications

OBJECTIVE: To evaluate the prevalence of pathogenic/likely pathogenic inherited cardiomyopathy variants and their association with heart failure in the (TOPMed) TransOmic for Precision of Medicine cohorts.

METHODS: A retrospective cohort study using the TOPMed cohorts, including multi-ancestry US adults (≥18 years of age) with sequencing data, was conducted. Pathogenic/likely pathogenic inherited cardiomyopathy variant carrier status was determined based on ClinVar variants classified with two or more stars of evidence. Individuals without pathogenic/likely pathogenic variants were used as the reference group. The primary outcome was heart failure , adjudicated by an expert panel. Cox proportional hazards models assessed the association between …

An Update On Non-Cigarette Nicotine-Containing Products And The Periodontal Patient, Brendan Keeney D.D.S., Ryan Schure Dds, Msc, Frcd

The New York State Dental Journal

The adverse general and oral health effects from traditional cigarette smoking are supported by decades of research. However, the use of cigarettes in the United States is on the decline, and current research and literature is relatively lacking with respect to novel nicotine consumption methods. Given the increasing and significant use of non-cigarette nicotine-containing products, such as electronic cigarettes, oral nicotine pouches and hookah pipes, attention from oral healthcare providers is warranted. An understanding of the potential negative periodontal outcomes related to these newer nicotine delivery systems is crucial to properly educating and treating patients today.

N Y State Dent J November 2025

The New York State Dental Journal

In the November 2025 issue, the reader will find the following feature articles:

• "Attitudes of New York State Pediatric Dentists Toward Treating Hasidic Patients"
• "A Qualitative Assessment of the Role of Dental Specialists in U.S. Opioid Epidemic"
• "Revolutionizing Dental Operatories"
• "An Update on Non-Cigarette Nicotine-Containing Products and the Periodontal Patient"

This issue includes regular columns with regional news impacting the New York membership including: editorial and legal columns, association activities, component news, continuing education opportunities, and classifieds.

The Art Of The Review: A 9-Step Guide For Beginning Researchers, Sandra Y. Desjardins, Tracy Ashby

TMC Library Newsletter (2015-)

Master the systematic review process from start to finish. This 30-minute course provides a comprehensive overview of nine essential steps. Learn how to plan, execute, and report on your systematic review with confidence.

Looking for more learning opportunities? Click here to view the full schedule of webinars offered throughout the fall semester.

Preferences For Clinical Trial Participation Among People Who Use Drugs In Rural Oregon And Appalachian Ohio, Kathryn E. Lancaster, Caroline W. Koudelka, Miriam R. Elman, Madison N. Enderle, Sarann Bielavitz, Angela T. Estadt, Ryan R. Cook, P. Todd Korthuis, April M. Young

Epidemiology and Environmental Health Faculty Publications

Background: Rural communities in the United States face significant challenges in participating in clinical trials, despite being heavily impacted by opioid and injection drug use epidemics. Barriers such as transportation, stigma, and limited resources often deter rural people who use drugs (PWUD) from engaging in research. Discrete choice experiments (DCEs) can help identify trial design features that support participation by eliciting participant preferences. Methods: We selected DCE attributes and attribute levels through literature review and qualitative interviews. Peer-based Retention of People who Use Drugs in Rural Research (PROUD-R²) study participants in rural Oregon and Appalachian Ohio completed the …

Seeing Beyond The State: Private Sector-Led Smart City Governance In Bsd City, Indonesia, Prerona Das, Orlando Woods, Lily Kong

Research Collection College of Integrative Studies

In recent decades new cities have sprung up at a rapid pace, aided by private sector funding (Hogan et al., 2012). Within the realm of smart city development, private sector influence over urban governance has substantially increased, particularly through Public-Private Partnerships (PPPs). However, in Indonesia, there is an emerging trend of the private sector exerting significant control over ‘independent’ greenfield smart cities beyond state-led frameworks. This paper develops the idea of seeing beyond the state which involves looking past conventional state-centered approaches to urban governance. It considers instead how power and control are exercised outside or beyond the usual boundaries …

Transforming Preterm Care: The Power Of Small Baby Guidelines In Enhancing Outcomes, Leeann Pavlek, Debra Armbruster, Cecilie Halling, Kaitlyn Hipp, Maria Jebbia, Susan Lopata, Matthew Rysavy, Rebecca Saliga, Sheria Wilson, Claire Beaullieu

Faculty, Staff and Student Publications

As survival rates of extremely preterm (EPT) infants continue to improve, focus has shifted to reduce morbidity and complications in these vulnerable patients. Management of EPT infants presents significant clinical, logistical, and sometimes ethical challenges. Outcomes across centers are highly variable and strongly influenced by the care provided in the early neonatal period. Standardized guidelines, based on published literature and center-specific experiences, play an important role in improving outcomes for EPT infants. Multidisciplinary guidelines provide a framework for clinical management and support a consistent care approach. Guidelines can improve care throughout the entire neonatal intensive care unit (NICU) course, beginning …

Draft 2026 Interim Site-Wide Surface Water Monitoring Quality Assurance Project Plan, Woodard & Curran

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Buy Better: How Food Policy Councils Leverage Procurement To Improve Food Worker Conditions, Frank Sarfo, Laura-Anne Minkoff-Zern, Jonnell A. Robinson

The Lender Center for Social Justice

Food system workers; farm laborers, grocery clerks, restaurant staff, and food processors are the backbone of our everyday meals, yet their voices are largely missing from the councils that shape local food policy. Despite being essential to food security and community health, these workers face low wages, poorworking conditions, and limited protections. Food Policy Councils (FPCs), which aim to advance equity and sustainability in food systems, rarely prioritize labor issues. The study, drawing on national survey data and interviews with over 25 FPC leaders, finds that structural constraints, internal conflicts, limited capacity, and weak connections with labor organizations prevent meaningful …

Do Underserved And Underrepresented Minorities Pay A Higher Premium For Employer-Sponsored Coverage?, Willie Reddic, Susan Albring, Patricia Crawford

The Lender Center for Social Justice

Employer-sponsored health insurance covers millions of Americans under 65, yet not all employees share the financial burden equally. This brief explores how underserved communities particularly Black, Hispanic, and American Indian/Alaska Native employees often pay a disproportionately high share of their income toward family coverage premiums. Drawing on national data and recent research, the study highlights systemic disparities in healthcare costs and access, that shows economic, social, and policy factors intersect to create uneven burdens. The importance of clear communication, tailored support tools, and equitable plan design to help employees make informed choices, while offering practical strategies for employers and entrepreneurs …

Stronger Together: The Case For Mda Membership, Cheri Newman Dds

The Journal of the Michigan Dental Association

MDA President Dr. Cheri Newman makes the case for membership, arguing that while automatic membership is no longer assumed, the value is essential to the profession. The primary benefit is the collective voice; without organized dentistry (MDA/ADA), dentists would lose advocacy and support, necessitating the eventual reinvention of the system. The COVID-19 pandemic highlighted the MDA's critical role as a trusted source for guidance on mandates and safe reopening. Beyond intangible advocacy, membership offers substantial, practical advantages that can easily cover the cost of dues. These advantages include financial savings on malpractice, liability, health, disability, and life insurance, along with …

Leaving Delaware? The Essential Role Of Specialized Corporate Courts, Zohar Goshen, Tomer S. Stein

Articles

Following the Delaware Court of Chancery's invalidation of Elon Musk's fifty-six-billion-dollar compensation package, Tesla moved its incorporation from Delaware to Texas. Shortly thereafter, Delaware's legislature, seeking to protect Delaware's dominant incorporation position, passed the most sweeping corporate law amendments in fifty years. 

Both supporters of Musk and defenders of Delaware's judiciary have accused each other of partisanship, but neither side has addressed the central question: What is the role of specialized corporate courts? 

This Essay presents a novel theory of why such courts are necessary. Corporate disputes are distinct because they arise within ongoing relationships between shareholders and management, governed …

The Anchor: November 2025, Hope College

The Anchor: 2025

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

The Reasonable Officer And The Disabled Subject, Jamelia N. Morgan

Vanderbilt Law Review

Police violence against disabled people is a  fundamental problem of policing. Whether through so called wellness checks, quality of life policing, or coercive state civil commitment procedures, disabled people are often on the receiving end of intrusion, violence, and rights violations by law enforcement. Yet, so, too, is everyone else. That disabled people are similarly, and yet uniquely, vulnerable to intrusion, violence, and rights violations by law enforcement might seem like just another group to add to the list of groups harmed by policing and police violence. However, the focus on disability does not merely bring to the forefront problems …

Comparison Of Alcohol-Induced Hepatoprotective Effects Of The High Fischer Ratio Oligopeptides With/Without Half Substitution By Pueraria Lobata, Yongke Deng, Qin Zhao, Na Chen, Zhiqin Zhang, Jingxuan Wang, Hongbing Fan, Haimei Liu, Lili Zhang

Animal and Food Sciences Faculty Publications

Long-term excessive intake of alcohol can cause serious damage to the liver, and the study of natural active ingredients with hepatoprotective effects is of great significance for the prevention and treatment of alcoholic liver injury. This study explored the ameliorative effects of high F-value oligopeptides (HFOPs) from Chlamys farreri, Pueraria lobata extract (PL), and their complex (HFOPs + PL) on alcoholic liver injury. Results showed HFOPs + PL significantly reduced alanine aminotransferase (ALT) and aspartate aminotransferase (AST) leakage, increased superoxide dismutase (SOD) and glutathione (GSH) activities, and decreased the production of malondialdehyde (MDA) and inflammatory factors in alcohol-induced HepG2 cells. …

Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao

Animal and Food Sciences Faculty Publications

The gonad is one of the major byproducts of sea cucumber. Four novel antioxidant peptides (NPWGQ, PGHPF, VPYPR and ATGPQGPAGQRGPAGPTGPTGPAG) were isolated and identified from sea cucumber gonad proteins through enzymatic hydrolysis and antioxidant activity-guided fractionation, bioinformatics approaches and in silico screening. These peptides demonstrated great free radical (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS))-scavenging activity and notable superoxide dismutase (SOD)-activation capacity. Molecular docking and molecular dynamics simulation data suggested that these peptides could form strong binding with SOD through hydrogen bonding, electrostatic interactions, and hydrophobic interactions. Among these peptides, NPWGQ displayed the most potent antioxidant and SOD-activating effects. Through searching …

The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun

Animal and Food Sciences Faculty Publications

This study evaluated the performance and energy and nutrient utilization of broiler chickens fed corn-soybean meal-based diets supplemented with a naturally fermented enzyme complex containing xylanase and phytase. This was evaluated using 300 one-day-old male Cobb broiler chicks in a randomized complete block design with five dietary treatments replicated 10 times with 6 chicks per replicate. The treatments consisted of a positive control (PC) group containing commercially recommended energy and nutrient levels, a negative control (NC) group with reduced metabolizable energy, calcium, and available phosphorus, and three levels of exogenous enzyme supplementation to the NC diet at 150, 200, 250 …

Law Library Blog (November 2025): Legal Beagle's Blog Archive, Roger Williams University School Of Law

Law Library Newsletters/Blog

No abstract provided.

Synthetic Data Generation Of Health And Demographic Surveillance Systems Data: A Case Study In A Low-And Middle-Income Country, Dorcas Mwigereri, Nigel Kamotho, Akbar Waljee, Ryan Rego, Eileen Weinheimer-Haus, Farhana Alarakhiya, Anthony Ngugi, Nicholson Price, Ji Zhu, Stephen Wong

Population Health, East Africa

Objective To evaluate effectiveness of open-source generative models in producing high-quality tabular synthetic data using a Health and Demographic Surveillance System (HDSS) dataset from rural Kenya, as a proof of concept in a low- and middle-income (LMIC) setting.

Materials and Methods Three open-source models (CTGAN, TableGAN, and CopulaGAN) were used to generate synthetic data from the Kaloleni/Rabai HDSS dataset. To assess the quality of the synthetic datasets generated by each model, we performed fidelity, utility, and privacy tests.

Results CTGAN outperformed the other models, producing synthetic data that closely mirrored the statistical properties of the real dataset while preserving privacy. …