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Changes In The Utilization Of Osteoporosis Drugs After The 2010 Fda Bisphosphonate Drug Safety Communication, Bander Balkhi, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio

Pharmacy Faculty Articles and Research

Introduction

In October 2010, the US Food and Drug Administration (FDA) issued a safety communication regarding the risks of atypical fractures of the femur, with bisphosphonates drugs. This study evaluated the impact of the bisphosphonates FDA safety communication on the utilization of osteoporosis medications in Medicaid programs.

Methods

Osteoporosis drugs utilization data from the July 2006 to June 2014 were extracted from the national Summary Files from the Medicaid State Drug Utilization Data maintained by the Centers for Medicare & Medicaid Services (CMS). We performed an interrupted time series analyses to evaluate trends in utilization of osteoporosis drugs before and …

Heterogeneous Anisotropy Index And Scaling In Multiphase Random Polycrystals, Muhammad Ridwan Murshed

Theses and Dissertations

Under consideration is the finite-size scaling of elastic properties in single and two-phase random polycrystals with individual grains belonging to any crystal class (from cubic to triclinic). These polycrystals are generated by Voronoi tessellations with varying grain sizes and volume fractions. By employing variational principles in elasticity, we introduce the notion of a 'Heterogeneous Anisotropy Index' and investigate its role in the scaling of elastic properties at finite mesoscales. The index turns out to be a function of 43 variables, 21 independent components for each phase and the volume fraction of either phase. Furthermore, the relationship between Heterogeneous Anisotropy Index …

Fort Hays State University Tiger Weekly, December 08, 2017, University Relations

Tiger Weekly Newsletters

No abstract provided.

Micromechanical Modeling Of The Soil Water Retention Curve Using A Coupled Discrete Element-Lattice Boltzmann Method, Jonathan Frank Fili

Theses and Dissertations

The Soil Water Retention Curve (SWRC) is a key constitutive relationship describing the behavior of variably saturated soils. The objective of this research is to assess the performance of a hydro-mechanical model, developed by coupling the lattice Boltzmann method (LBM) with the discrete element method (DEM), for micromechanical simulation of the SWRC. The DEM-LBM model is used to examine the effects of wave propagation on fluid-solid interaction. A multi-phase LBM is then employed within a static particle array generated by the DEM to examine the effects of initial fluid density distribution. The SWRCs are generated by recording the liquid pore …

Large-Scale Graph Visual Analytics, Fangyan Zhang

Theses and Dissertations

Large-scale graph analysis and visualization is becoming a more challenging task, due to the increasing amount of graph data. This dissertation focuses on methods to ease the task of exploring large-scale graphs through graph sampling and visualization. Graph sampling aims to reduce the complexity of graph drawing, while preserving properties of the original graph, allowing analysis of the smaller sample which yields the characteristics similar to those of the original graph. Graph visualization is an effective and intuitive approach to observing structures within graph data. For large-scale graphs, graph sampling and visualization are straightforward strategies to gain insights into common …

Commencement Ceremonies, University Of North Florida

Commencement Printed Materials

Program for the Fall Commencement ceremonies.

2017-December-08-Dada Does Christmas, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Dry Ingredient Dispenser, Group S, 2017, Nick Caywood, Noelle T. Wojciechowsi

Mechanical Engineering Design Project Class

We wanted to come up with a way to automate the process of measuring and dispensing dry ingredients for baking.

The Automatic Bartender, Richard Wu, Alex Nassar, Keegan Lathrum

Mechanical Engineering Design Project Class

The automatic bartender will hold 2 liquors and 2 mixers. When the user selects the option to make a drink, the device will pour out the required amounts of liquid into a container, via tubing that feeds into the container. The container has an internal stirrer to mix the components together, and then empties into a cup. The end result is a finished cocktail, and the machine is designed for residential use.

2018 Asme Student Design Competition - Group T Senior Design Project, Thomas Hess, Anker Anderson, Drew Daugherty, Jack Dufelmeier

Mechanical Engineering Design Project Class

The purpose of this project is to create a single soccer playing robot to compete in the 2018 ASME student design competition. The robot, along with spare parts and all other devices must fit inside a 50x50x50 cm box. This robot must be able to traverse the field via remote control and have the ability to control a tennis ball and shoot it with sufficient force.

Cross-Curricular Writing In Mathematics For Comprehension, Kirsten Stowell

Honors Theses

Even though the idea of implementing writing in a mathematics classroom is far from new and the benefits from doing so are hardly nonexistent, this concept is often not found in modern secondary mathematics classrooms. Writing about mathematics allows students to organize and communicate their thinking, gain a better conceptual understanding of mathematical topics, develop a stronger sense of mathematical procedure, move beyond surface-level thinking, and place abstract ideas into context. Writing can also be used by teachers as a formative assessment to explicitly determine if students are struggling conceptually or procedurally in a mathematics classroom to then adjust instruction …

Foreign Price-Fixing Conspiracies, Christopher R. Leslie

Duke Law Journal

Although price-fixing agreements remain per se illegal in the United States, courts have undermined the per se rule against price fixing by making it harder for plaintiffs to prove that such an agreement exists. For example, most courts that have considered the issue have held that defendants’ price-fixing conduct in a foreign market is not probative of price fixing in the United States. This Article examines the relationship between foreign and domestic price-fixing activity and shows how expanding a price-fixing cartel from foreign markets into the United States benefits the cartel by reducing the risk of arbitrage, stabilizing the cartel, …

Introduction Of Iodised Salt Benefits Infants’ Mental Development In A Community-Based Cluster-Randomised Effectiveness Trial In Ethiopia, Karim Bougma, Frances E. Aboud, Tizita M. Lemma, Edward A. Frongillo Jr., Grace S. Marquis

Faculty Publications

The effectiveness of salt iodisation in improving the mental development of young children has not been assessed. We implemented a community-based cluster-randomised effectiveness trial in sixty randomly selected districts in the Amhara region of Ethiopia. We randomly allocated each district to treatment and randomly selected one of its villages. In parallel to national salt iodisation efforts, iodised salt was brought early into the markets of the thirty intervention villages before it became widely available in the thirty control villages 4–6 months later. The primary outcome was children’s mental development scores on the Bayley Scales. This was an intention-to-treat analysis using …

African American Male Students' Perceptions Of The Community College Experience In Rural Louisiana And How It Influences Graduation And Retention Rates, Aaron Jagers

Theses and Dissertations

This quantitative study explored the obstacles African American male students face that can hinder their academic progress at community colleges within the rural regions of Louisiana. This study viewed the collective experiences of African American males in community colleges in order to improve their academic outcomes, completion, and retention rates. This study also explored the African American male’s educational experiences and the personal and academic obstacles they faced as students in the community college environment. This study used a research design that collected data from African American male students in two rural Louisiana community colleges. This study utilized a survey …

African American Males' Identification Of Factors That Contributed To Their Community College Persistence, Ulissa Byshelle Coburn

Theses and Dissertations

In spite of an expanding enrollment of African American males in community colleges in the United States, the early departure of this minority group is one of concern. The purpose of this qualitative study was to explore African American males’ identification of the factors that contributed to their persistence at community colleges. Data were collected through structured interviews with 7 African American male community college graduates who were enrolled at a 4-year university when the study was conducted. Data were analyzed through by coding and categorizing in order to determine themes. Social integration and social cognitive models were used to …

An Analysis Of Signaling Processes Leading To A Defense Response In Soybean, Brandon Trey Mcneece

Theses and Dissertations

Plant-parasitic nematodes are the cause of devastating yield loss in vital agricultural crops around the world. Heterodera glycines, also referred to as soybean cyst nematode, is the main pathogen of Glycine max (soybean) causing more loss than all other pathogens of G. max combined. The resultant economic impact due to H. glycines in United States soybean production alone is estimated to account for an annual one-billion-dollar loss. Natural resistant genotypes have been found in trials to combat this pathogen. Of the resistant varieties identified, G. max[Peking/PI 548402] and G. max[PI 88788] are the major sources of resistance. Identification of genes …

Application Of Non-Targeted Volatile Metabolomics In Plant Pathology, Jinyan She

Theses and Dissertations

Our study focuses on the application of volatile metabolomics and chemometrics in plant pathology. Specifically, volatile metabolites or volatile organic compounds (VOCs) from the American chestnut tree (Castanea dentata) and its pathogenic fungus Cryphonectria parasitica have been investigated. The American chestnut was once a dominant tree species in the eastern forests of the United States. However, it was nearly devastated by the fungal pathogen C. parasitica. The loss of this tree species has significantly impacted the ecosystem. Therefore, preservation and restoration of American chestnut are crucial. Chapter one provides an overview of mass spectrometry based volatile metabolomics and their implementation …

Authentic Leadership, Research Integrity, And Institutions Of Higher Learning: Why Focusing On Departmental Leadership Is Critical For Preserving The Sanctity Of Science, Katherine I. Echols

Theses and Dissertations

One of the most overlooked and complex problems that universities and colleges face nation-wide is how to reduce and eliminate research misconduct. Because of the confidential nature of allegations of research misconduct and the high rate of underreporting, administrators at scholarly institutions struggle with understanding the cause of such behavior. Without a clear picture of the prevalence of misconduct or the barriers to reporting, leaders at institutions of higher learning find themselves at a disadvantage when dealing with these problems. This uncertainty coupled with a growing regulatory emphasis from federal funding agencies, results in a reactionary approach while questionable practices …

Classification And Significance Assessments Of Occupations On The Ackerman Unit Of The Tombigbee National Forest, Mississippi, Mary A. Madden

Theses and Dissertations

The Ackerman Unit of the Tombigbee National Forest has served as the location of numerous archaeological investigations. Despite all of the work done, there is a question of whether a representative sample of the archaeological record has been saved and subsequently whether the reports and findings from the Ackerman Unit of the Tombigbee National Forest are legitimate and can be applied to a larger body or research at the regional, and even national scale. This thesis will evaluate whether a paradigmatic classification of occupations can be used to assess if a representative sample of the archaeological record has been saved, …

Evaluating The Validity Of Latency Effects In Robotics Simulation, Leif T. Jensen

Theses and Dissertations

Latency is a common issue found in robotics teleoperation that is not currently addressed in simulation. This study examined the effects of latency on operator performance for a robot teleoperation navigation task. Operators used a Logitech gamepad controller to teleoperate a robot through both a simulated environment and real-world environment. Both environments had the same dimensions and provided a path with obstacles the participant had to navigate. Participants performed this navigation task under three latency conditions, zero, low and high. Completion time, number of collisions, NASA-TLX, System Usability Survey, and User Experience survey were collected and participant performance compared for …

Field Methods, Sampling Strategies, Historical Documents, And Data Redundancy: A Study Of Historic Tenant Farmsteads In Leflore County, Mississippi, Jayson Jon Zoino

Theses and Dissertations

Historic tenant farmsteads are often thought to be redundant archaeological resources because of their limited temporal range and function which acts to limit the diversity of their archaeological assemblages. However, work has not been done that confirms this equivalence, and archaeologists often write off tenant farmsteads as being too modern or too disturbed to warrant investigation. This is a problematic approach as tenant farmsteads are quickly eroding from the American landscape and a representative sample of sites need to be investigated and preserved before they’re gone. This thesis tests different sampling strategies and field methods that may allow for the …

Controlling Forage Weed Species Detrimental To Livestock Production, David Pierce Russell

Theses and Dissertations

Among the vast diversity of plants in the mid-South to which grazing livestock are exposed, there is a need to address certain species that are potentially harmful to livestock health and production. Field and greenhouse experiments were conducted on endophyte-infected tall fescue [Schedonorus arundinaceus (Schreb.) Dumort = Lolium arundinaceum (Schreb.) Darbysh.], a cool-season perennial forage, and perilla mint, (Perilla frutescens (L.) Britton) an herbaceous annual, to determine management techniques and control measures for healthier pasture and livestock systems. When seedheads reached maturity, spring and autumn glyphosate applications at 1.68 kg ae ha-1, coupled with autumn tillage and summer and winter …

Demonstration Of Ultra-High Recyclable Energy Densities In Domain-Engineered Ferroelectric Films, Hongbo Cheng, Jun Ouyang, Yun-Xiang Zhang, David J. Ascienzo, Yao Li, Yu-Yao Zhao, Yuhang Ren

Publications and Research

Dielectric capacitors have the highest charge/discharge speed among all electrical energy devices, but lag behind in energy density. Here we report dielectric ultracapacitors based on ferroelectric films of Ba(Zr0.2,Ti0.8)O3 which display high-energy densities (up to 166 J cm–3) and efficiencies (up to 96%). Different from a typical ferroelectric whose electric polarization is easily saturated, these Ba(Zr0.2,Ti0.8)O3 films display a much delayed saturation of the electric polarization, which increases continuously from nearly zero at remnant in a multipolar state, to a large value under the maximum electric field, leading to drastically improved recyclable energy densities. This is achieved by the creation …

A Happy Marriage Of Inconvenience: The Power Of Adrienne De La Fayette Over Her Destiny In Eighteenth-Century France, Brittany I. Fox

Pell Scholars and Senior Theses

Extensive analysis and interpretation have occurred concerning the Marquis de Lafayette and his contributions to the American War for Independence and the Revolutionary French era. However, the discourse on his wife, Adrienne de Noailles, the Marquise de La Fayette, has been confined to a chapter within her husband's larger narrative. Examining her agency over her circumstances, Adrienne proves to be more than an idealistic angel suffering from a tumultuous time period.

Creating A More Certain Standard For Enhanced Patent Damages By Requiring Egregiousness As An Element In The Section 284 Analysis, Brian Barnes

Duke Law Journal

According to 35 U.S.C. § 284, district courts have the power to “increase the damages up to three times the amount found or assessed” by the jury in patent infringement cases where willful infringement occurred. Following the recent Supreme Court decision in Halo Electronics, Inc. v. Pulse Electronics, Inc., it is now less clear how courts are to go about deciding whether to exercise this power. Halo established that the decision lies within the discretion of the district court judge, but declined to give a more concrete standard than urging the judge to “take into account the particular circumstances …

One Good Plaintiff Is Not Enough, Aaron-Andrew P. Bruhl

Duke Law Journal

This Article concerns an aspect of Article III standing that has played a role in many of the highest-profile controversies of recent years, including litigation over the Affordable Care Act, immigration policy, and climate change. Although the federal courts constantly emphasize the importance of ensuring that only proper plaintiffs invoke the federal judicial power, the Supreme Court and other federal courts have developed a significant exception to the usual requirement of standing. This exception holds that a court entertaining a multiple-plaintiff case may dispense with inquiring into the standing of each plaintiff as long as the court finds that one …

Algorithms & Fiduciaries: Existing And Proposed Regulatory Approaches To Artificially Intelligent Financial Planners, John Lightbourne

Duke Law Journal

Artificial intelligence is no longer solely in the realm of science fiction. Today, basic forms of machine learning algorithms are commonly used by a variety of companies. Also, advanced forms of machine learning are increasingly making their way into the consumer sphere and promise to optimize existing markets. For financial advising, machine learning algorithms promise to make advice available 24–7 and significantly reduce costs, thereby opening the market for financial advice to lower-income individuals. However, the use of machine learning algorithms also raises concerns. Among them, whether these machine learning algorithms can meet the existing fiduciary standard imposed on human …

The Cosm Aggregate, Georgia Southern University

College of Science & Mathematics: News & Publications (2012-2022)

No abstract provided.

The Effects Of Institutional Structure Of Predominantly White Land-Grant Colleges And Universities In The Southeast On African American Graduation Rates In Engineering, Angela Denice Clinkscales Verdell

Theses and Dissertations

The U.S. Department of Labor reports that only 5% of U.S. workers are employed in fields related to science and engineering, yet they are responsible for more than 50% of our sustained economic expansion (U.S Department of Labor, 2007). Furthermore, minorities makeup 0.0025 % (1/400) of that Science, Technology, Engineering, and Mathematics (STEM) workforce. Methods are currently underway to understand and address the attrition of minority students in the STEM workforce. The problem of underrepresentation of minorities (URMs) in STEM careers continues to result in a “leaky pipeline” where URMs have cited institutional factors such “chilly campus” climates as barriers …

The Effects Of The First Year Of Implementation Of Positive Behavioral Intervention Supports, Rosalind Flanigan Operton

Theses and Dissertations

Disciplinary practices and protocols in schools have been a notable concern over the past 30 years. The traditional punitive punishment-based tactics have not proven to be effective in changing student behavior. Positive Behavior Intervention Supports (PBIS) is a proactive alternative that puts whole school systems in a place wherein students and teachers share in the responsibility of building a culture and climate of behaviors that produce positive outcomes. Research based on the implementation of PBIS in schools has concluded that problem behaviors decrease, students and staff feel safe, and attendance improves. There is a body of research that concludes that …