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2017

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Mri In Cancer: Improving Methodology For Measuring Vascular Properties And Assessing Radiation Treatment Effects In Brain, Chong Duan Aug 2017

Mri In Cancer: Improving Methodology For Measuring Vascular Properties And Assessing Radiation Treatment Effects In Brain, Chong Duan

Arts & Sciences Graduate Student Theses and Dissertations

Tumors cannot survive, progress and metastasize without recruiting new blood vessels. Vascular properties, including perfusion and permeability, provide valuable information for characterizing cancers and assessing therapeutic outcomes. Dynamic contrast-enhanced (DCE) MRI is a non-invasive imaging technique that affords quantitative parameters describing the underlying vascular structure of tissue. To date, the clinical application of DCE-MRI has been hampered by the lack of standardized and validated quantitative modeling approaches for data analysis.From a therapeutic perspective, radiation therapy is a central component of the standard treatment for patients with cancer. Besides killing cancer cells, radiation also induces parenchymal and stromal changes in normal …

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Determining The Molecular Mechanisms Of Huntington’S Disease Through Multi-Scale Modeling, Kiersten Ruff Aug 2017

Determining The Molecular Mechanisms Of Huntington’S Disease Through Multi-Scale Modeling, Kiersten Ruff

Arts & Sciences Graduate Student Theses and Dissertations

Huntington’s disease (HD) is associated with a mutational CAG repeat expansion within exon 1 of the huntingtin (Htt) gene. Post-transcriptional processing leads to the generation of N-terminal Htt protein fragments (Htt-NTFs), including those that encompass exon 1 (Httex1). Within Httex1, the CAG-repeat encoded polyglutamine (polyQ) tract is flanked N-terminally by a 17-residue amphipathic stretch (N17) and C-terminally by a 50-residue proline rich (PR) domain. Htt-NTFs, including Httex1, are among the smallest fragments that recapitulate HD pathology in mouse models. However, the direct link between Htt-NTFs with polyQ expansions and neurodegeneration that leads to HD remains unresolved. Despite being a monogenic …

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Sequence Determinants Of The Individual And Collective Behaviour Of Intrinsically Disordered Proteins, Alexander S. Holehouse Aug 2017

Sequence Determinants Of The Individual And Collective Behaviour Of Intrinsically Disordered Proteins, Alexander S. Holehouse

Arts & Sciences Graduate Student Theses and Dissertations

Intrinsically disordered proteins and protein regions (IDPs) represent around thirty percent of the eukaryotic proteome. IDPs do not fold into a set three dimensional structure, but instead exist in an ensemble of inter-converting states. Despite being disordered, IDPs are decidedly not random; well-defined - albeit transient - local and long-range interactions give rise to an ensemble with distinct statistical biases over many length-scales. Among a variety of cellular roles, IDPs drive and modulate the formation of phase separated intracellular condensates, non-stoichiometric assemblies of protein and nucleic acid that serve many functions. In this work, we have explored how the amino …

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Is There A Higher-Order Mechanism That Explains Performance Across Prediction Tasks?, Michelle Lisa Eisenberg Aug 2017

Is There A Higher-Order Mechanism That Explains Performance Across Prediction Tasks?, Michelle Lisa Eisenberg

Arts & Sciences Graduate Student Theses and Dissertations

People constantly make predictions about what will happen in the near future. People anticipate how other people around them will act, what other people will say, and what actions will help them achieve the greatest rewards. Because all of these behaviors are typically called prediction, it is easy to make the assumption that performance across all of these types of tasks is driven by the same underlying mechanism. However, there has been little investigation into whether the mechanisms underlying prediction are the same across multiple task modalities. Therefore, in the current study, 226 participants completed four types of tasks that …

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Understanding Household, Network, And Organizational Drivers Of Adoption Of Cleaner Cooking Fuels In Rural India, Praveen Kumar Aug 2017

Understanding Household, Network, And Organizational Drivers Of Adoption Of Cleaner Cooking Fuels In Rural India, Praveen Kumar

Arts & Sciences Graduate Student Theses and Dissertations

Adoption of evidence-based cleaner cooking systems such as Liquefied Petroleum Gas (LPG) is a crucial first step in eventually providing a sustainable solution for household air pollution. To promote adoption of LPG in below poverty line households, we require evidence-based implementation strategies. For these strategies to be feasible and scalable, they need to be grounded in a thorough understanding of the household, network, and organizational level drivers of LPG adoption. However, systematic research on adoption of LPG by poor communities is still lacking.The overall objective of the study was to develop a better understanding about new insights on the reach …

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Participation In Governance And Well-Being In The Yukon Flats, Jessica Charlene Black Aug 2017

Participation In Governance And Well-Being In The Yukon Flats, Jessica Charlene Black

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation explains the relationship between participation in governance and well-being in the Yukon Flats. To garner a deeper understanding of this relationship, definitions of governance and well-being are sought from the participants, thus providing holistic, Indigenous definitions of these concepts. Both formal and informal governance are also explored to understand the important institutions that underpin these larger relationships. Lastly, this dissertation investigates the relationship between participation in traditional hunting, fishing, and gathering and well-being in the Yukon Flats. Qualitative methods, including semi-structured interviews, observations, and photographs are all used to document these relationships. Applied thematic analysis is used due …

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Founders Keepers Newsletter 2017-08-15, Niu Libraries Aug 2017

Founders Keepers Newsletter 2017-08-15, Niu Libraries

University Libraries Archives

No abstract provided.

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Temperature-Modulated Expression Of Allometric Respiration Strategies Supports A Metabolic Scaling Rule, Chet F. Rakocinski, Kelsey Burns Gillam Aug 2017

Temperature-Modulated Expression Of Allometric Respiration Strategies Supports A Metabolic Scaling Rule, Chet F. Rakocinski, Kelsey Burns Gillam

Faculty Publications

A model based on the mass-specific oxygen consumption rate of the tolerant polychaete, Capitella telata, related meaningfully to a novel metabolic scaling rule as applied to the infaunal size spectrum. Depending on temperature, C. telataexpressed divergent oxyregulating or oxyconforming strategies relative to oxygen availability. A non-linear response surface fitted to the allometric exponents of a family of VO2 curves for 12 treatment combinations of DO saturation and temperature was used to project oxygen consumption rates across the infaunal size spectrum. Plasticity in respiration strategies was evident, based on four simulated dynamic 32 d oxygen-temperature exposure scenarios and …

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Review Of Training Principles For Flight Training In Aircraft Or Simulator, Stefan Kleinke Aug 2017

Review Of Training Principles For Flight Training In Aircraft Or Simulator, Stefan Kleinke

National Training Aircraft Symposium (NTAS)

In human-performance-driven fields such as the social and behavioral sciences and education, there is a particular risk for a disconnect between current research and applied practice. Often, new findings require policy changes and workforce re-education before being applied in a meaningful way. Therefore, a continuous need for practitioner professional development and continuation training exists to ensure informed practices. This presentation is motivated by these needs and aims to help flight training professionals to make informed decisions when designing and conducting flight training events. Based on a conceptual framework of cognitive and behavioral theories in learning, a variety of common training …

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Notes On Contributors Aug 2017

Notes On Contributors

The Journal of Social Encounters

No abstract provided.

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Fostering Cultures Of Encounter: Framing Papal Teaching On Dialogue As Multi-Track Peacebuilding, Maria Power, Christopher Hrynkow Aug 2017

Fostering Cultures Of Encounter: Framing Papal Teaching On Dialogue As Multi-Track Peacebuilding, Maria Power, Christopher Hrynkow

The Journal of Social Encounters

This article demonstrates that there is a rough parallel between (1) Diamond and McDonald’s (1996) notion of multi-track diplomacy and (2) the four levels of inter-religious dialogue identified by the Pontifical Council for Interreligious Dialogue, along with two other levels discerned within papal teaching by the authors. Diamond and McDonald expanded the political science concept of dual-track diplomacy and, in the process, helped to buttress the legitimacy of peace studies discourse in that discipline. Comparably, this article seeks to introduce papal teaching on dialogue framed in terms of multi-track peacebuilding. As a result, it solidifies a latent resonance between Catholic …

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Toward An Integral Catholic Peacebuilding, Gerard Powers Aug 2017

Toward An Integral Catholic Peacebuilding, Gerard Powers

The Journal of Social Encounters

Among the many under-examined aspects of Catholic approaches to peacebuilding are its ecclesiological and practical dimensions. This article suggests that an Integral Catholic Peacebuilding calls for deepening the Catholic community’s commitment to peacebuilding as a vocation, especially by reinvigorating the lay vocation; cultivating distinctively Catholic approaches to peacebuilding while engaging inclusively, especially through strategic approaches to ecumenical and inter-religious engagement; and promoting greater integration by examining the interconnections among disparate factors and issues, and giving priority to effective collaboration among vertical and horizontal levels, and different sectors of the Catholic community

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Sensory-Friendly Mode For Mobile Devices, Philip Weaver, Tim Salau Aug 2017

Sensory-Friendly Mode For Mobile Devices, Philip Weaver, Tim Salau

Defensive Publications Series

A system and method are disclosed for a sensory-friendly mode in a mobile device. The system allows users to adjust the display, sound or haptic feedback output of the device to optimize the ability of users to consume the information provided by the device. The system may vary the amount of visual complexity for display based on the user needs, either by blurring the screen to eliminate hard edges, making the unimportant areas of the screen entirely invisible or by applying time-based filters to prevent animations or prevent screen flickering. The system may adjust audio volume automatically when a volume …

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September 14, 2017, James Madison University Aug 2017

September 14, 2017, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

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Dual Modality Code Explanations For Novices: Unexpected Results, Briana B. Morrison Aug 2017

Dual Modality Code Explanations For Novices: Unexpected Results, Briana B. Morrison

Computer Science Faculty Proceedings & Presentations

The research in both cognitive load theory and multimedia principles for learning indicates presenting information using both diagrams and accompanying audio explanations yields better learning performance than using diagrams with text explanations. While this is a common practice in introductory programming courses, often called "live coding," it has yet to be empirically tested. This paper reports on an experiment to determine if auditory explanations of code result in improved learning performance over written explanations. Students were shown videos explaining short code segments one of three ways: text only explanations, auditory only explanations, or both text and auditory explanations, thus replicating …

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2017 – The Development Of The Land Tenure And Water Systems In California And Specifically In The Salinas Valley Groundwater Basin [Draft] Aug 2017

2017 – The Development Of The Land Tenure And Water Systems In California And Specifically In The Salinas Valley Groundwater Basin [Draft]

Related Research and Documents

Beginning with the Aboriginal era through the Spanish, Mexican and United States eras, maps and governmental documents reflect the state of knowledge concerning California (and the Salinas Valley) along with the driving needs and policies that determined how water was used and managed. By examining the maps, it is possible to determine the state of knowledge in Europe (and later in the United States) as it related to the physical and geographical attributes of California prior to colonization and subsequently throughout the Spanish and Mexican periods. Governmental documents provide a window to how land was used and granted during the …

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Carotid Body-Mediated Chemoreflex Drive In The Setting Of Low And High Output Heart Failure., Rodrigo Del Rio, David C. Andrade, Camilo Toledo, Hugo S. Diaz, Claudia Lucero, Alexis Arce-Alvarez, Noah J. Marcus, Harold D. Schultz Aug 2017

Carotid Body-Mediated Chemoreflex Drive In The Setting Of Low And High Output Heart Failure., Rodrigo Del Rio, David C. Andrade, Camilo Toledo, Hugo S. Diaz, Claudia Lucero, Alexis Arce-Alvarez, Noah J. Marcus, Harold D. Schultz

Journal Articles: Cellular & Integrative Physiology

Enhanced carotid body (CB) chemoreflex function is strongly related to cardiorespiratory disorders and disease progression in heart failure (HF). The mechanisms underlying CB sensitization during HF are not fully understood, however previous work indicates blood flow per se can affect CB function. Then, we hypothesized that the CB-mediated chemoreflex drive will be enhanced only in low output HF but not in high output HF. Myocardial infarcted rats and aorto-caval fistulated rats were used as a low output HF model (MI-CHF) and as a high output HF model (AV-CHF), respectively. Blood flow supply to the CB region was decreased only in …

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The Mechanism Of Alpha Lipoic Acid On Reducing The Mda Level And Mcp-1 Expression In Endothelial Dysfunction Of Hypercholesterolemia Rat (Rattus Norvegicus) Model, Dewi Perwito Sari, Imam Susilo, Junaidi Khotib Aug 2017

The Mechanism Of Alpha Lipoic Acid On Reducing The Mda Level And Mcp-1 Expression In Endothelial Dysfunction Of Hypercholesterolemia Rat (Rattus Norvegicus) Model, Dewi Perwito Sari, Imam Susilo, Junaidi Khotib

Folia Medica Indonesiana

Endothelial dysfunction is an initial condition of atherosclerosis and other vascular diseases where one of the risk factors is hypercholesterolemia. Blood cholesterol levels is associated with an increase in the production of reactive oxygen species (ROS). The increasing of ROS production can cause increased oxidative stress which in turn resulting in endothelial dysfunction. Alpha lipoic acid (ALA) is one of the antioxidant compound that has been developed and studied. In this study we found that the use of ALA in Rattus norvegicus rats signifficantly lower the total cholesterol levels at dose 60 mg/kgBW (p=0.020). ALA also inhibit the expression of …

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The Effect Of Administering Mangosteen Rind Extract (Garnicia Mangostana L) Compared With Glimepiride To The Blood Sugar Levels Of White Male Rat (Rattus Norwegicus L) Induced By Streptozotocin, Hasyim As'ari, Dewi Mutmainnah Mahartini Aug 2017

The Effect Of Administering Mangosteen Rind Extract (Garnicia Mangostana L) Compared With Glimepiride To The Blood Sugar Levels Of White Male Rat (Rattus Norwegicus L) Induced By Streptozotocin, Hasyim As'ari, Dewi Mutmainnah Mahartini

Folia Medica Indonesiana

The purpose of this study is to prove the differential effect of administering the mangosteen Rind extract due to lowering the blood sugar levels of Winstar white male rats induced by streptozotosin (STZ). This study used a randomized design of the ramdomized posttest only control group design. The sample consisted of 4 groups with a sample size of 7 animals each group of rats. All samples were prepared STZ induction of diabetes with a single dose of 50 mg/Kg BW through intraperitoneal (IP). K0 (control group; given 1% CMC 1 cc/day), K1 (treatment group 1; given 0,054 mg glimepiride/200 grBW, …

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Proceedings Of The 2017 Berry Summer Thesis Institute, University Of Dayton. University Honors Program Aug 2017

Proceedings Of The 2017 Berry Summer Thesis Institute, University Of Dayton. University Honors Program

Proceedings of the Berry Summer Thesis Institute (2013-Present)

Thanks to a gift from the Berry Family Foundation and the Berry family, the University Honors Program launched the Berry Summer Thesis Institute in 2012. The institute introduces students in the University Honors Program to intensive research, scholarship opportunities and professional development. Each student pursues a 12-week summer thesis research project under the guidance of a UD faculty mentor. This contains the product of the students' research.

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Anthropologists Weigh In On The Sustainability Of Tourism, Michael A. Di Giovine Aug 2017

Anthropologists Weigh In On The Sustainability Of Tourism, Michael A. Di Giovine

Anthropology & Sociology Faculty Publications

No abstract provided.

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Seladelpar (Mbx-8025), A Selective Ppar-Δ Agonist, In Patients With Primary Biliary Cholangitis With An Inadequate Response To Ursodeoxycholic Acid: A Double-Blind, Randomised, Placebo-Controlled, Phase 2, Proof-Of-Concept Study., David Jones, Pol F. Boudes, Mark G. Swain, Christopher L. Bowlus, Michael R. Galambos, Bruce R. Bacon, Yvonne Doerffel, Norman Gitlin, Stuart C. Gordon, Joseph A. Odin, David Sheridan, Markus Alexander Wörns, Virginia Clark, Linsey Corless, Heinz Hartmann, Mark E. Jonas, Andreas E. Kremer, George F. Mells, Peter Buggisch, Bradley L. Freilich, Cynthia Levy, John M. Vierling, David E. Bernstein, Marek Hartleb, Ewa Janczewska, Fedja Rochling, Hemant Shah, Mitchell L. Shiffman, John H. Smith, Yun Jung Choi, Alexandra Steinberg, Monika Varga, Harinder Chera, Robert Martin, Charles A. Mcwherter, Gideon M. Hirschfield Aug 2017

Seladelpar (Mbx-8025), A Selective Ppar-Δ Agonist, In Patients With Primary Biliary Cholangitis With An Inadequate Response To Ursodeoxycholic Acid: A Double-Blind, Randomised, Placebo-Controlled, Phase 2, Proof-Of-Concept Study., David Jones, Pol F. Boudes, Mark G. Swain, Christopher L. Bowlus, Michael R. Galambos, Bruce R. Bacon, Yvonne Doerffel, Norman Gitlin, Stuart C. Gordon, Joseph A. Odin, David Sheridan, Markus Alexander Wörns, Virginia Clark, Linsey Corless, Heinz Hartmann, Mark E. Jonas, Andreas E. Kremer, George F. Mells, Peter Buggisch, Bradley L. Freilich, Cynthia Levy, John M. Vierling, David E. Bernstein, Marek Hartleb, Ewa Janczewska, Fedja Rochling, Hemant Shah, Mitchell L. Shiffman, John H. Smith, Yun Jung Choi, Alexandra Steinberg, Monika Varga, Harinder Chera, Robert Martin, Charles A. Mcwherter, Gideon M. Hirschfield

Peninsula Medical School

BACKGROUND: Many patients with primary biliary cholangitis have an inadequate response to first-line therapy with ursodeoxycholic acid. Seladelpar is a potent, selective agonist for the peroxisome proliferator-activated receptor-delta (PPAR-δ), which is implicated in bile acid homoeostasis. This first-in-class study evaluated the anti-cholestatic effects and safety of seladelpar in patients with an inadequate response to ursodeoxycholic acid. METHODS: The study was a 12-week, double-blind, placebo-controlled, phase 2 trial of patients with alkaline phosphatase of at least 1·67 times the upper limit of normal (ULN) despite treatment with ursodeoxycholic acid. Patients, recruited at 29 sites in North America and Europe, were randomly …

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Economic And Environmental Sustainability Of Heifer Development Strategies In Pasture-Based Organic Dairy Systems, S. Clay Isom Aug 2017

Economic And Environmental Sustainability Of Heifer Development Strategies In Pasture-Based Organic Dairy Systems, S. Clay Isom

Funded Research Records

No abstract provided.

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Aggression, Impulsivity, And Symptom Severity: An Examination Of Risk Factors For Violent Behaviors, Melissa Charfadi Aug 2017

Aggression, Impulsivity, And Symptom Severity: An Examination Of Risk Factors For Violent Behaviors, Melissa Charfadi

Theses and Dissertations

This study sought to explore the relationship between psychopathology, aggression, and impulsivity. Two hypotheses were derived from the existing scientific literature: First, as a validity check, we anticipated that levels of psychopathology would be related to both aggression and impulsivity (as previously reported data suggests). Second, we anticipated that impulsivity would moderate the relationship between overall symptom severity and aggression. Finally, we constructed exploratory regression models to examine the contribution of specific types of impulsivity in the prediction of specific acts of aggression across BSI symptom groupings. Data was collected using Rowan University undergraduate students that completed an in-person battery …

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Novel Influences Of Il-10 On Cns Inflammation Revealed By Integrated Analyses Of Cytokine Networks And Microglial Morphology., Warren D. Anderson, Andrew D. Greenhalgh, Aditya Takwale, Samuel David, Rajanikanth Vadigepalli Aug 2017

Novel Influences Of Il-10 On Cns Inflammation Revealed By Integrated Analyses Of Cytokine Networks And Microglial Morphology., Warren D. Anderson, Andrew D. Greenhalgh, Aditya Takwale, Samuel David, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Coordinated interactions between cytokine signaling and morphological dynamics of microglial cells regulate neuroinflammation in CNS injury and disease. We found that pro-inflammatory cytokine gene expression in vivo showed a pronounced recovery following systemic LPS. We performed a novel multivariate analysis of microglial morphology and identified changes in specific morphological properties of microglia that matched the expression dynamics of pro-inflammatory cytokine TNFα. The adaptive recovery kinetics of TNFα expression and microglial soma size showed comparable profiles and dependence on anti-inflammatory cytokine IL-10 expression. The recovery of cytokine variations and microglial morphology responses to inflammation were negatively regulated by IL-10. Our novel …

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Comparison Effect Of Cv 12, St 36 And St 40 Ea On Short Term Energy Balance Regulation In High Fat Diet Rat, Purwo Sri Rejeki, Harjanto Harjanto, Raden Argarini, Imam Subadi Aug 2017

Comparison Effect Of Cv 12, St 36 And St 40 Ea On Short Term Energy Balance Regulation In High Fat Diet Rat, Purwo Sri Rejeki, Harjanto Harjanto, Raden Argarini, Imam Subadi

Folia Medica Indonesiana

The aim of this study was to determine the comparative effects of EA (EA) on the CV12, ST36 and ST40 to weight gain prevention over the short-term regulation of energy balance. The study was conducted with a completely randomized design. Rats were divided into five groups: negative control group (no treatment, n=5), positive control (sham EA/back, n=5), EA CV 12 (n=6), EA ST 36 (n=6) and EA ST 40 (n=7). Rats were exposed to high-fat diet for two weeks and EA was simultaneously performed once daily, five days a week for two weeks with 2 Hz, for 10 minutes with …

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In Vitro Fertility Test Of Human Spermatozoa Membrane Protein Fertilin Beta Antibody In Mice (Mus Musculus Balb/C) As Immunocontraceptive Candidate, Reny I'Tishom, Doddy M Soebadi, Aucky Hinting, Hamdani Lunardhi, Rina Yudiwati Aug 2017

In Vitro Fertility Test Of Human Spermatozoa Membrane Protein Fertilin Beta Antibody In Mice (Mus Musculus Balb/C) As Immunocontraceptive Candidate, Reny I'Tishom, Doddy M Soebadi, Aucky Hinting, Hamdani Lunardhi, Rina Yudiwati

Folia Medica Indonesiana

One of the materials as potential candidates immunocontraception material is spermatozoa. Fertilin beta is spermatozoa membrane protein and is found only in mature spermatozoa and ejaculate, which serves as an adhesion molecule. Spermatozoa membrane protein that is used as an ingredient immunocontraception candidate, must have specific criteria that the specificity of spermatozoa, the role of antigen in the fertilization process, which includes the formation of immunogenicity sufficient antibody response has the potential to block fertilization. Antibodies against spermatozoa affect the stages before fertilization of the reproductive process and can hinder the development of the embryo after fertilization. Until now very …

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The Effect Of Long Term Administration Of Glucocorticoid To Bone Lining Cells Apoptosis, Gadis Meinar Sari Aug 2017

The Effect Of Long Term Administration Of Glucocorticoid To Bone Lining Cells Apoptosis, Gadis Meinar Sari

Folia Medica Indonesiana

Glucocorticoid is widely used in medical treatment as an immune system or an inflammation therapy. However its long term administration can cause life-threatening side effects. One of them is bone mass loss which increases the risk of bone fractures in the long-term use. Bone lining cells derived from mesenchymal stem cells, which serve as a backup cell bone-forming osteoblasts. Glucocorticoids acting directly on osteoblasts, bone lining cells when reduced due to increased apoptosis, the reserve cells to bone formation will be decreased. The aim of this study was to count the amount of apoptotic bone lining cells after long term …

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Nursing Care For A Patient With Nstemi Admitted To The Coronary Care Unit For Percutaneous Coronary Intervention — A Case Study, Siti Maryati M. S., Dioso R. (Ii) P. Aug 2017

Nursing Care For A Patient With Nstemi Admitted To The Coronary Care Unit For Percutaneous Coronary Intervention — A Case Study, Siti Maryati M. S., Dioso R. (Ii) P.

ASEAN Journal on Science and Technology for Development

This case studyaims to demonstrateclinical nursing skills to a patient with myocardial infarction admitted for percutaneous coronary intervention. Nursing care for this patient startedwith a physical assessment and laboratory invesigation analysis. This evaluation was necessary to develop a nursing care plan. The activities in the ward enumerated the medications provided, and the details of the vital signs monitored hourly. The patient was sent to cardiac catheter laboratory at 1030H. From the cardiac catheter laboratory post-percutaneouscoronary intervention to the mid-right coronary artery (1 Drug-Eluting Stent) he was transferred out to Telemetry unit on 11 August2016 at 1500H with Terumo band hemostatic …

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Analysis Of Earphone Swab Mitochondrial Dna As An Alternative Material For Identification Examination, Ahmad Yudianto, Yeti Eka Sispitasri, Nola Margaret Aug 2017

Analysis Of Earphone Swab Mitochondrial Dna As An Alternative Material For Identification Examination, Ahmad Yudianto, Yeti Eka Sispitasri, Nola Margaret

Folia Medica Indonesiana

Identification include fingerprint, property, medical, dental, serologic and exclusion methods. In the development, identification methods led to molecular forensics, a new field of science evolving since the 1980s, known as DNA fingerprinting. Specimens widely used in DNA assay for identification are blood spots/bloods, semen spots, vaginal swabs, buccal swabs and bones. In addition to these specimens, the last objects often used by the perpetrators/victims can be used, such as hearing aids (headsets/earphones). In its use, earphones are attached to the outer ear skin; thus, the earwax is suspected to adhere to the device. To date, in Indonesia personal identification is …

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