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Spatiotemporal Identification Of Anomalies In A Wildlife Preserve, Bharadwaj Kishan, Jason Guan Jie Ong, Yanrong Zhang, Tin Seong Kam

Research Collection School Of Computing and Information Systems

The datasets released for the VAST Challenge 2017 comprise vehicle movement data captured with RFID sensors, chemical emission data from factories captured by gas sensors, and image attributes of the wildlife plant health obtained from satellites, all pertaining to a fictional wildlife preserve. Using visual analytics, a compelling hypothesis is established to link the spatiotemporal datasets to the phenomenon, where the count of a bird specimen is found to decline over a given year. Anomalies in vehicle traffic patterns are linked to proximal factory emissions, and further associated with satellite imagery that show proof of degradation in plant quality in …

Gametophyte Fitness And Costs Of Self-Fertilization In The Giant Kelp Macrocystis Pyrifera, Robert A. San Miguel

Capstone Projects and Master's Theses

It is widely established that inbreeding can incur heavy costs in a variety of plants, animals, and algae. To date, ten species of kelp have been tested to ascertain the degree to which selfing reduces recruitment of juvenile sporophytes and of those ten species, seven have reduced recruitment when inbred. In this study, I set out to understand whether there is variability in response to self-fertilization among giant kelp gametophytes grown from multiple sites, what those differences are, and how it affects sporophyte recruitment. I collected reproductive sporophylls from fifteen Macrocystis pyrifera individuals in Point Loma, Leo Carrillo State Beach, …

Nutrient Dynamics In Tidally Restricted Regions Of The Elkhorn Slough National Estuarine Research Reserve, Maureen M. Wise

Capstone Projects and Master's Theses

The Elkhorn Slough, in the heart of the Monterey Bay, includes water bodies that have been isolated from tidal flushing cycles by dikes, levees, roads and train tracks. This partitioning has changed the functionality of these systems primarily through reduced circulation and increased eutrophication. The Elkhorn Slough is surrounded by a patchwork of lands under varied land-uses, including open space, developed properties, and extensive agriculture, that results in high and variable nutrient loading into the surrounding aquatic habitat. Water bodies of restricted flow disproportionately exhibit impacts due to this loading. In this study, nutrient concentrations were measured using both discrete …

An Algorithmic Approach To Operative Management Of Complex Pediatric Dog Bites: 3-Year Review Of A Level I Regional Referral Pediatric Trauma Hospital, Kaveh Alizadeh, A Shayesteh, M Xu

NYMC Faculty Publications

Background: Incidence of dog bites continues to rise among the pediatric population and serves as a public health threat for the well-being of children. Plastic surgeons are at the forefront of initial management and eventual outcome of these devastating injuries. This study set out to determine the nature of dog bite injuries treated over a 3-year period at a large level 1 pediatric trauma center. Methods: A retrospective review of emergency room records of all pediatric patients (age, 0-18 years old) who sustained dog bites between January 2012 and December 2014 were gathered. All details about age of patient, location …

Complete Genome Sequence Of A Colistin-Resistant Escherichia Coli Strain Harboring Mcr-1 On An Inchi2 Plasmid In The United States, V Gilrane, S Lobo, Weihua Huang, J Zhuge, Changhong Yin, Donald Chen, K Alvarez, Alexandra Budhai, I Nadelman, Nevenka Dimitrova, John Fallon, Guiqing Wang

NYMC Faculty Publications

We report here the incidental detection and complete genome sequence of a urinary Escherichia coli strain harboring mcr-1 and resistant to colistin in a New York patient returning from Portugal in 2016. This strain, with sequence type 1485 (ST1485), was a non-extended-spectrum beta-lactamase (ESBL) and non-carbapenemase producer and carried the mcr-1 gene on an IncHI2 plasmid.

Corrigendum: Attenuation Of Na/K-Atpase Mediated Oxidant Amplification With Pnaktide Ameliorates Experimental Uremic Cardiomyopathy, J Liu, J Tian, M Chaudhry, K Maxwell, Y Yan, Nader Abraham, J Shapiro, Nader Abraham, Z Xie, J Shapiro

NYMC Faculty Publications

This corrects the article DOI: 10.1038/srep34592.

Detection And Molecular Status Of Isospora Sp. From The Domestic Pigeon (Columba Livia Domestica)., Ryuma Matsubara, Yasuhiro Fukuda, Fumi Murakoshi, Osamu Nomura, Toru Suzuki, Chika Tada, Yutaka Nakai

Department of Biochemistry and Molecular Biology Faculty Papers

The domestic pigeon, Columba livia domestica, is reared for meat production, as a pet, or for racing. Few reports have characterized the parasitic protists from the genus Isospora isolated from Columbiformes. We detected Isospora-like oocysts from C. livia reared for racing. The oocyst contained two sporocysts, and each sporocyst included four sporozoites. The sporulated oocysts (n=4) were spherical; their mean diameters were 25.6 (24.0-27.2)×24.7 (23.4-26.0) μm. Micropyles, polar granules, and oocyst residuum were absent. The mean length and width of the sporocysts (n=8) were 19.5 (18.5-20.5) and 11.2 (10.2-12.1) μm, respectively. Stieda and sub-Stieda bodies were observed. Single-oocyst PCR revealed …

The Nearness Of You, Tianyi Yin

Theses

The Nearness Of You is an animated 2D graduate thesis film. The entire film, including the credits, is 4 minutes 55 seconds long. The production phase went from September 2016 to May 2017.

This is a love story about two mannequins. The story takes place in a European looking city. The male mannequin meets the female mannequin under a romantic scenario.They fall in love as the time pass by. However, in the end, they don’t get to actually end up together. As a result, the male mannequin gets to have a symbolic figure as the female mannequin and they spend …

Mighty Rapalink-1 Vanquishes Undruggable Mutant Mtor In Glioblastoma, Meena Jhanwar-Uniyal

NYMC Faculty Publications

No abstract provided.

Rethinking Dalian New International Airport: The Exploration Of A Net-Zero Airport Powered By Tidal Power Energy On An Artificial Island., Xiaofan Jiang

Theses

Fossil fuel is still the number one energy resource in China, and among the fossil fuel, coal is the primary resource to generate electricity and heat during heating days. Fossil fuel will result in global warming, sea level rising, but we may not perceive these because of the relatively subtle changes. Nevertheless, China got the punishment from the natural in recent years, most of the mainland China is experiencing the terrible smog, which gets worse in the winter. The cause of the smog is same to London, a huge amount of coal has been consumed in last few decades. To …

The Path Report Volume 1 Issue 2, Pathology Department, New York Medical College

The Path Report

No abstract provided.

Sleeper Cells: The Stringent Response And Persistence In The Borreliella (Borrelia) Burgdorferi Enzootic Cycle, Felipe C. Cabello, Henry Godfrey, J Bugrysheva, Stuart A. Newman

NYMC Faculty Publications

Infections with tick-transmitted Borreliella (Borrelia) burgdorferi, the cause of Lyme disease, represent an increasingly large public health problem in North America and Europe. The ability of these spirochetes to maintain themselves for extended periods of time in their tick vectors and vertebrate reservoirs is crucial for continuance of the enzootic cycle as well as for the increasing exposure of humans to them. The stringent response mediated by the alarmone (p)ppGpp has been determined to be a master regulator in B. burgdorferi. It modulates the expression of identified and unidentified open reading frames needed to deal with and overcome the many …

Heroic Restorations: Dryden And Milton, Thomas Luxon

Dartmouth Scholarship

No abstract provided.

Solarworld Amidst Uncertainty, Palak Goel, Roland Richards, Asawari Kulkarni, Nagarjun Hassan Ranganath, Majed Alshamlani

Engineering and Technology Management Student Projects

Solar energy is turning out to be a widely accepted renewable energy alternative. It is considered as the cleanest and abundantly available source of energy. Adoption of this source for energy generation has been made possible by technological advancements. The United States has realized the potential of the solar energy but hasn’t been able to exploit the technology until recently. Since 2009, the US has seen a significant growth in consumption of solar energy. Efficiency of solar cells, tax credits, state policies, increasing public awareness on environmental pollution have resulted in increasing use of solar energy. Although a key reason …

Loyalty To Nature: Royce's Latent Environmental Philosophy, Albert R. Spencer

Philosophy Faculty Publications and Presentations

This article surveys recent attempts to articulate the latent environmental philosophy of Josiah Royce (Selk; Oppenheim; Price; Bell; Minteer; Brunson) and to assess the merits and flaws of these attempts. It will then orient Royce's latent environmental philosophy within the context of contemporary methodologies of environmental ethics in the hopes of demonstrating Royce's relevance and potential to these engagements of current ecological crises. It will conclude by articulating a unique perspective of loyalty to nature founded on a Roycean appeal to moral perfectionism, his response to the egoism of Friedrich Nietzsche, and a blending of the sources presented at the …

Johnson Creek Bacteria Tmdl Implementation: Status And Trend Analysis Study, John Gala

Environmental Science and Management Professional Master's Project Reports

Like many other waterbodies in the United States, Johnson Creek, a tributary of the Lower Willamette River is water quality limited for bacteria. Escherichia coli (E. coli), a member of the fecal coliform bacteria group, has been found to have a high association with human pathogens and the occurrences of gastrointestinal illnesses in waters used for contact recreation; E. coli is commonly used as an indicator of fecal contamination. In the State of Oregon water contact recreational standards for fecal exposure is assessed by measuring in stream levels of E. coli. Because Johnson Creek is water quality …

Formalizing The Panarchy Adaptive Cycle With The Cusp Catastrophe [Presentation], Martin Zwick, Joshua Hughes

Complex Systems Faculty Publications and Presentations

The panarchy adaptive cycle, a general model for change in natural and human systems, can be formalized by the cusp catastrophe of René Thom's topological theory. Both the adaptive cycle and the cusp catastrophe have been used to model ecological, economic, and social systems in which slow and small continuous changes in two control variables produce fast and large discontinuous changes in system behavior. The panarchy adaptive cycle, the more recent of the two models, has been used so far only for qualitative descriptions of typical dynamics of such systems. The cusp catastrophe, while also often employed qualitatively, is a …

Construction And Characterization Of A Single Stage Dual Diaphragm Gas Gun, Nathaniel Steven Helminiak

Master's Theses (2009 -)

In the interest of studying the propagation of shock waves, this work sets out to design, construct, and characterize a pneumatic accelerator that performs high-velocity flyer plate impact tests. A single stage gas gun with a dual diaphragm breach allows for a non-volatile, reliable experimental testing platform for shock phenomena. This remotely operated gas gun utilizes compressed nitrogen to launch projectiles down a 14 foot long, 2 inch diameter bore barrel, which subsequently impacts a target material of interest. A dual diaphragm firing mechanism allows the 4.5 liter breech to reach a total pressure differential of 10ksi before accelerating projectiles …

Assessment Of Intra And Interregional Genetic Variation In The Eastern Red-Backed Salamander, Plethodon Cinereus, Via Analysis Of Novel Microsatellite Markers, Alexander C. Cameron, Jeffry J. Anderson, Robert B. Page

Biology Faculty Publications (Archived)

The red-backed salamander (Plethodon cinereus) has long-served as a model system in ecology, evolution, and behavior, and studies surveying molecular variation in this species have become increasingly common over the past decade. However, difficulties are commonly encountered when extending microsatellite markers to populations that are unstudied from a genetic perspective due to high levels of genetic differentiation across this species’ range. To ameliorate this issue, we used 454 pyrosequencing to identify hundreds of microsatellite loci. We then screened 40 of our top candidate loci in populations in Virginia, Pennsylvania, and Ohio—including an isolated island population ~ 4.5 km off the …

Burning In New Mexico, Tasha A. Vice

Reading Faculty Publications (Archived)

No abstract provided.

Effects Of Carboxylated Nanodiamonds On Macrophages During And After Differentiation, Maisoun E. Bani Hani

Biological Sciences Theses & Dissertations

Nanodiamonds (ND) are a carbon-based nanomaterial that are increasingly being proposed for developing novel imaging techniques, as carriers of biomolecules and therapeutic drugs, as coatings for implants, and for other biomedical applications. The exceptional chemical, mechanical, and optical properties of ND make this material suitable in a wide range of fields. The application of ND in the biomedical field is attractive but requires more in-depth investigation into the safety of ND and its interactions with different cells and systems. The effects of ND on the immune system are not fully understood or investigated and there are several controverting reports regarding …

Biology And Impacts Of Leech Infestation In Largemouth Bass (Micropterus Salmoides) In Back Bay, Virginia, Amanda Nicole Pomposini

Biological Sciences Theses & Dissertations

Back Bay is an oligohaline coastal bay in Southeast Virginia, USA. The Oregon Inlet along the Outer Banks of North Carolina is the only significant salinity source to the Bay via the Pamlico and Currituck Sounds of North Carolina. Today Back Bay is considered a brackish ecosystem with salinity of 2004, leeches have been observed in the oral cavities of Largemouth Bass (Micropterus salmoides) in Back Bay. Leeches (Myzobdella lugubris) have previously been documented in the oral cavities of largemouth bass in the Currituck Sound. In 2009, the Virginia Department of Game and Inland Fisheries (VDGIF) …

Development And Validation Of A Hybrid Virtual/Physical Nuss Procedure Surgical Trainer, Mohammad F. Obeid

Computational Modeling & Simulation Engineering Theses & Dissertations

With continuous advancements and adoption of minimally invasive surgery, proficiency with nontrivial surgical skills involved is becoming a greater concern. Consequently, the use of surgical simulation has been increasingly embraced by many for training and skill transfer purposes. Some systems utilize haptic feedback within a high-fidelity anatomically-correct virtual environment whereas others use manikins, synthetic components, or box trainers to mimic primary components of a corresponding procedure.

Surgical simulation development for some minimally invasive procedures is still, however, suboptimal or otherwise embryonic. This is true for the Nuss procedure, which is a minimally invasive surgery for correcting pectus excavatum (PE) – …

Effect Of Bioglass Incorporation Into Electrochemically Aligned Collagen Threads On Mechanical Properties And Cell-Mediated Mineralization, Madhura Nijsure

Theses and Dissertations

Bone related diseases and disorders are a significant socioeconomic burden in the United States. Autografts and allografts are most commonly used for the treatment of bone defects and non-unions; however, they are associated with limitations such as donor site morbidity and immune rejection, respectively. Over the past few decades, bone tissue engineering (BTE) using scaffold and cells has garnered significant interest as an alternative method for the repair and regeneration of bone defects. Recreation of the tissue microenvironment via the development of biomimetic scaffolds that resemble the physicochemical aspects (i.e., composition, topography, stiffness) of native bone is a promising approach …

Ormeloxifene Suppresses Prostate Tumor Growth And Metastatic Phenotypes Via Inhibition Of Oncogenic Β-Catenin Signaling And Emt Progression, Bilal B. Hafeez, Aditya Ganju, Mohammed Sikander, Vivek K. Kashyap, Zubair Bin Hafeez, Neeraj Chauhan, Shabnam Malik, Andrew Massey, Manish Tripathi, Fathi T. Halaweish, Murali M. Yallapu, Subhash C. Chauhan, Meena Jaggi

School of Medicine Publications

Ormeloxifene is a clinically approved selective estrogen receptor modulator, which has also shown excellent anticancer activity, thus it can be an ideal repurposing pharmacophore. Herein, we report therapeutic effects of ormeloxifene on prostate cancer and elucidate a novel molecular mechanism of its anticancer activity. Ormeloxifene treatment inhibited epithelial-to-mesenchymal transition (EMT) process as evident by repression of N-cadherin, Slug, Snail, vimentin, MMPs (MMP2 and MMP3), β-catenin/TCF-4 transcriptional activity, and induced the expression of pGSK3β. In molecular docking analysis, ormeloxifene showed proficient docking with β-catenin and GSK3β. In addition, ormeloxifene induced apoptosis, inhibited growth and metastatic potential of prostate cancer cells and …

Understanding The Contributions Of Beef Cattle To Greenhouse Gas Emissions, Elizabeth Stewart, Eric Thacker, Matthew D. Garcia, Juan J. Villalba

All Current Publications

This fact sheet describes current and projected beef consumption, methane, nitrogen, beef cattle production, and possibilities for more sustainable beef production.

Growing Hummingbird Mint In Utah Gardens, Taun Beddes, Michael Caron

All Current Publications

This fact sheet describes hummingbird mints, a group of ornamental herbaceous perennials, that bloom from early summer to fall. It describes varieties, fertilization, planting and irrigation, diseases and pests and maintenance.

Peptidyl-Prolyl Isomerase 1 Regulates Ca(2+) Handling By Modulating Sarco(Endo)Plasmic Reticulum Calcium Atpase And Na(2+)/Ca(2+) Exchanger 1 Protein Levels And Function, V Sacchi, B Wang, D Kubli, A Martinez, J Jin, R Alvarez, N Hariharan, C Glembotski, T Uchida, J Malter, Y Yang, P Gross, C Zhang, S Houser, Marcello Rota, M Sussman

NYMC Faculty Publications

BACKGROUND: Aberrant Ca(2+) handling is a prominent feature of heart failure. Elucidation of the molecular mechanisms responsible for aberrant Ca(2+) handling is essential for the development of strategies to blunt pathological changes in calcium dynamics. The peptidyl-prolyl cis-trans isomerase peptidyl-prolyl isomerase 1 (Pin1) is a critical mediator of myocardial hypertrophy development and cardiac progenitor cell cycle. However, the influence of Pin1 on calcium cycling regulation has not been explored. On the basis of these findings, the aim of this study is to define Pin1 as a novel modulator of Ca(2+) handling, with implications for improving myocardial contractility and potential for …

Aquaculture And Mcr Colistin Resistance Determinants, Felipe C. Cabello, Alexandra Tomova, Larisa Ivanova, Henry Godfrey

NYMC Faculty Publications

No abstract provided.

Sodium Dynamics In Pyramidal Neuron Dendritic Spines: Synaptically Evoked Entry Predominantly Through Ampa Receptors And Removal By Diffusion, K Miyazaki, William N. Ross

NYMC Faculty Publications

Dendritic spines are key elements underlying synaptic integration and cellular plasticity, but many features of these important structures are not known or are controversial. We examined these properties with newly developed simultaneous sodium and calcium imaging that had single spine resolution in pyramidal neurons in rat hippocampal slices from either sex. Indicators for both ions were loaded through the somatic patch pipette, which also recorded electrical responses. Fluorescence changes were detected with a high speed, low noise CCD camera. Following subthreshold electrical stimulation postsynaptic sodium entry is almost entirely through AMPA receptors with little contribution from entry through NMDA receptors …