Digital Commons Network^™

Inside The Aviary, Nikki Mehle

Theses and Dissertations

Modularity and movement of energy are two key concepts in the construction of Nikki Mehle's paintings. Painting is an act of both processing and creating reality – the duality of reflection and invention.

Healthy People Are Bad For Capitalism, Eri King

Theses and Dissertations

Healthy People are Bad For Capitalism is a four part installation that creates an alternative space for the chemicals, Red 40 and Monosodium Glutamate. Presented as a holistic center that offers healing services and remedies, Center for the Red 40 and MSG Healing explores the homeopathic doctrine of Like Cures Like (what make a human ill also cures them) through the relationship between Traditional Japanese Healing Practices, and Western Capitalism.

Healthy People are Bad For Capitalism presents Red 40 MSG Apothecary, Red 40 Zen MSG Healing Rock Garden, Theta Wave Eternal Flame Meditation and Red 40 MSG …

Southern Grotesque, Maggie Ellis

Theses and Dissertations

The scenes I paint are submerged in specific landscapes I have encountered in Georgia. Honoring my experiences from this vantage point, I depict the rough and tumble attitude of my upbringing that is at odds with a rarefied New York art world I currently live in.

Music From The Harpsichord House, Julie Zhu

Theses and Dissertations

Music from the Harpsichord House is an installation and series of concerts that exists in the binary of in and out of performance. During a concert, the harpsichordist is hidden inside the house and his face is live-projected outside. Fifteen new musical compositions were commissioned for the harpsichord house.

"Nothing Is Wrong With You", Carlos Rigau

Theses and Dissertations

Just as one object can give rise to multiple percepts, so an object may fail to give rise to any percept at all: if the percept has no grounding in a person's experience, the person may literally not perceive it.”

Perception literally guides human understanding as to what reality and truth is. My work intends to ruffle up commonly understood western percepts and their normality. I consistently choose media comprised of static images, moving images and sculpture. These forms are used to convey a singular and independent meaning, as well as a larger collective expression.

Four Legs Good, Two Legs Bad: How Slaughterhouse Safety Hasn’T Kept Up With The Times, Emily Ziemski

Capstones

From legal loopholes and outdated rules to undetectable infections and understaffing, the United States Department of Agriculture may not be doing all it can to make sure the American public’s health isn't at risk. As the people of the United States consume over 500 million pounds of beef a year, food safety policy and slaughterhouses are falling behind in proper procedural measurements in the beef industry.

emziemski.com/capstone

How The “Greatest Rapper Alive” Returned Hip Hop To Its Political Roots, Meeran Karim

Capstones

Rapper Kendrick Lamar’s powerful documentation of his own personal struggles and that of a country overcome with racial strife have revitalized the genre of hip hop music. More than just the “greatest rapper alive,” Lamar is also one of the most important storytellers in America today.

Capstone Link:

https://medium.com/@meeran.karim/kendrick-lamar-hiphop-political-roots-19e3f5e48385

Type 2 Neural Progenitor Cell Activation Drives Reactive Neurogenesis After Binge-Like Alcohol Exposure In Adolescent Male Rats, Chelsea Rhea Geil Nickell, Hui Peng, Dayna M. Hayes, Kevin Y. Chen, Justin A. Mcclain, Kimberly Nixon

Pharmaceutical Sciences Faculty Publications

Excessive alcohol consumption during adolescence remains a significant health concern as alcohol drinking during adolescence increases the likelihood of an alcohol use disorder in adulthood by fourfold. Binge drinking in adolescence is a particular problem as binge-pattern consumption is the biggest predictor of neurodegeneration from alcohol and adolescents are particularly susceptible to the damaging effects of alcohol. The adolescent hippocampus, in particular, is highly susceptible to alcohol-induced structural and functional effects, including volume and neuron loss. However, hippocampal structure and function may recover with abstinence and, like in adults, a reactive burst in hippocampal neurogenesis in abstinence may contribute to …

Voluntary And Involuntary Isolation In Mary Shelley's The Last Man, Jessica Pope Mudrow

Criterion: A Journal of Literary Criticism

No abstract provided.

The Shadow's Symphony: Archetypal Awakening In Igor Stravinsky's The Rite Of Spring, Rebekah Hood

Criterion: A Journal of Literary Criticism

No abstract provided.

The Fourth Amendment Disclosure Doctrines, Monu Bedi

William & Mary Bill of Rights Journal

The third party and public disclosure doctrines (together the “disclosure doctrines”) are long-standing hurdles to Fourth Amendment protection. These doctrines have become increasingly relevant to assessing the government’s use of recent technologies such as data mining, drone surveillance, and cell site location data. It is surprising then that both the Supreme Court and scholars, at times, have associated them together as expressing one principle. It turns out that each relies on unique foundational triggers and does not stand or fall with the other. This Article tackles this issue and provides a comprehensive topology for analyzing the respective contours of each …

Characterization Of Structural Dynamics Of The Human Head Using Magnetic Resonance Elastography, Andrew Arun Badachhape

McKelvey School of Engineering Graduate Student Theses & Dissertations

In traumatic brain injury (TBI), the skull-brain interface, composed of three meningeal layers: the dura mater, arachnoid mater, and pia mater, along with cerebrospinal fluid (CSF) between the layers, plays a vital role in transmitting motion from the skull to brain tissue. Magnetic resonance elastography (MRE) is a noninvasive imaging modality capable of providing in vivo estimates of tissue motion and material properties. The objective of this work is to augment human and phantom MRE studies to better characterize the mechanical contributions of the skull-brain interface to improve the parameterization and validation of computational models of TBI. Three specific aims …

Image Reconstruction Of The Speed Of Sound And Initial Pressure Distributions In Ultrasound Computed Tomography And Photoacoustic Computed Tomography, Thomas Paul Matthews

McKelvey School of Engineering Graduate Student Theses & Dissertations

Ultrasound computed tomography (USCT) and photoacoustic computed tomography (PACT) are two emerging imaging modalities that have a wide range of potential applications from pre-clinical small animal imaging to cancer screening in human subjects. USCT is typically employed to measure acoustic contrasts, including the speed of sound (SOS) distribution, while PACT typically measures optical contrasts or some related quantity such as the initial pressure distribution. Their complementary contrasts and similar implementations make USCT and PACT a natural fit for a hybrid imaging system. Still, much work remains to realize this promise. First, USCT image reconstruction methods based on the acoustic wave …

Analysis Of Argonaute-Small Rna-Transcription Factor Circuits Controlling Leaf Development, John Steen Hoyer

Arts & Sciences Graduate Student Theses and Dissertations

Experimental studies of plant development have yielded many insights into gene regulation, revealing interactions between core transcriptional and post-transcriptional regulatory pathways present in all land plants. This work describes a direct connection between the three main small RNA-transcription factor circuits controlling leaf shape dynamics in the reference plant Arabidopsis thaliana. We used a high-throughput yeast 1-hybrid platform to identify factors directly binding the promoter of the highly specialized ARGONAUTE7 silencing factor. Two groups of developmentally significant microRNA-targeted transcription factors were the clearest hits from these screens, but transgenic complementation analysis indicated that their binding sites make only a small contribution …

Understanding The Paradox Of Genetic Diversity In Uropathogenic E. Coli: The Uncommon Evolution Of A Common Pathogen, Henry Louis Schreiber

Arts & Sciences Graduate Student Theses and Dissertations

Urinary tract infections (UTIs) are the second most common bacterial infection of people in the U.S.A and are frequently recurrent, as an initial UTI is quickly followed by a second episode in 30-35% of cases despite appropriate antibiotic treatment and clearance of the bacteria from the urine. The vast majority, >80%, of UTIs are caused by uropathogenic Escherichia coli (UPEC). UPEC that colonize the bladder are thought to originate in the gut, where they live as commensal organisms. UPEC can be shed in feces to colonize the vagina and/or periurethral area, and then can ascend into the bladder to start …

Bridging The Translational Gap Between Rodent And Human Pain Research, Tayler Diane Sheahan

Arts & Sciences Graduate Student Theses and Dissertations

The treatment of chronic pain is an immense clinical and societal burden rooted in the ineffectiveness and adverse side effects of existing analgesics. Extensive efforts have been directed towards the development of novel pain therapies with maximal efficacy and minimal unwanted effects; however, putative therapeutic targets identified in preclinical rodent models rarely translate in clinical trials. The poor translational record of basic pain research findings has been attributed, in part, to the use of suboptimal rodent pain models and behavioral endpoints used to assess putative analgesics, as well as differences in the pharmacological profiles of rodents and humans. The work …

Structured Illumination Diffuse Optical Tomography For Mouse Brain Imaging, Matthew Reisman

Arts & Sciences Graduate Student Theses and Dissertations

As advances in functional magnetic resonance imaging (fMRI) have transformed the study of human brain function, they have also widened the divide between standard research techniques used in humans and those used in mice, where high quality images are difficult to obtain using fMRI given the small volume of the mouse brain. Optical imaging techniques have been developed to study mouse brain networks, which are highly valuable given the ability to study brain disease treatments or development in a controlled environment. A planar imaging technique known as optical intrinsic signal (OIS) imaging has been a powerful tool for capturing functional …

Serum Amyloid A3 Is A High Density Lipoprotein-Associated Acute-Phase Protein, Lisa R. Tannock, Maria C. De Beer, Ailing Ji, Preetha Shridas, Victoria P. Noffsinger, Laura Den Hartigh, Alan Chait, Frederick C. De Beer, Nancy R. Webb

Internal Medicine Faculty Publications

Serum amyloid A (SAA) is a family of acute-phase reactants. Plasma levels of human SAA1/SAA2 (mouse SAA1.1/2.1) can increase ≥ 1,000-fold during an acute-phase response. Mice, but not humans, express a third relatively understudied SAA isoform, SAA3. We investigated whether mouse SAA3 is an HDL-associated acute-phase SAA. Quantitative RT-PCR with isoform-specific primers indicated that SAA3 and SAA1.1/2.1 are induced similarly in livers (∼2,500-fold vs. ∼6,000-fold, respectively) and fat (∼400-fold vs. ∼100-fold, respectively) of lipopolysaccharide (LPS)-injected mice. In situ hybridization demonstrated that all three SAAs are produced by hepatocytes. All three SAA isoforms were detected in plasma of LPS-injected mice, although …

Diet And Activity Patterns Of Five Bat Species In North-Central Kansas, Holly G. Wilson

Master's Theses or Doctor of Nursing Practice

My study focuses on six bat species that occur in north-central Kansas. Although each species is widely distributed, information about their diet and activity patterns is lacking, especially within Kansas. Increased knowledge about bat species in Kansas can provide a baseline for future studies and conservation efforts for the species included in my study; big brown bat (Eptesicus fuscus), eastern red bat (Lasiurus borealis), hoary bat (Lasiurus cinereus), northern myotis (Myotis septentrionalis), evening bat (Nycticeius humeralis), and tricolored bats (Perimyotis subflavus) were captured and fecal samples were examined for diet diversity. I captured bats in mist nets in the Kansas …

Acquisition Of Aquatic Motor Skills Through Children’S Motor Stories, Juan Antonio Moreno Murcia, Elisa Huescar Hernandez, Jose Antonio Richart Parra

International Journal of Aquatic Research and Education

An increasing interest in the renewal of traditional recreational content and the use of the aquatic environments as educational resources is supported by very few empirical, evidence-based studies that link the two. This quasi-experimental study analyzed the role of stories in influencing perceived motor competence and real motor skills in seventy-eight children ages between 4 and 5 years through the administration of two questionnaires on aquatic motor ability and aquatic motor competence. Differences were found in aquatic motor competence (p < .01) and aquatic motor ability (p < .05) for the experimental group, where higher means values were obtained after the intervention. We present this methodological proposal as a useful educational tool for early childhood stimulation with achievements that go beyond motor progress itself.

Guns And Sorcery: Raiding, Trading, And Kanaima Among The Makushi, James Andrew Whitaker

Tipití: Journal of the Society for the Anthropology of Lowland South America

Raiding, trading, and sorcery are historically-interrelated phenomena among the Makushi Amerindians in Guyana. Colonial documents reveal that the Makushi were heavily targeted during the eighteenth and early nineteenth centuries by Luso-Brazilian and Amerindian slavers. The form of such slaving frequently fluctuated between raiding and trading and formed a nexus around which practices of sorcery came to be centred. A connexion between the historical positions of the Makushi as victims of slaving and practitioners of kanaima sorcery has been identified by Neil Whitehead, who hypothesized that kanaima practices gained socially-sanctioned applications as the introduction of guns led to transformations in traditional …

Persuasive Kinship: Human–Plant Relations In Southwest Amazonia, Fabiana Maizza

Tipití: Journal of the Society for the Anthropology of Lowland South America

Based on my ethnographic research with the Jarawara people, an indigenous society in the Southwest Amazonia, the article explores the idea of thinking kinship as persuasion. Among the Jarawara, children can have more than one father, which is well known in Americanist literature, but there would exist as well an original practice what we could call "multi-maternity". I also observe that the Jarawara can have diverse parental relations - some of their children are human, while others are plants. This occurs in a system of raising (nayana) in which children and plants are raised by a father and/or a mother …

Cosmology Performed, The World Transformed: Mimesis And The Logical Operations Of Nature And Culture In Myth In Amazonia And Beyond, Deon Liebenberg

Tipití: Journal of the Society for the Anthropology of Lowland South America

By analyzing myths from around the world to build an argument regarding the relation between cosmology and community, Amazonian myths are set within a broader set of mythic imageries. Lévi-Strauss showed how a structural description of myth should fully incorporate the entire set of variant arrangements through which its elements or terms could be related to one another. Despite the criticism to which his approach has been subject, the notion that certain kinds of logical operations could be gleaned in the organization of myth continues to yield valuable insights. In this paper, I contend that the mimetic representation of empirically …

Radical Territories In The Brazilian Amazon: The Kayapó’S Fight For Just Livelihoods By Laura Zanotti, Diego Soares Da Silveira

Tipití: Journal of the Society for the Anthropology of Lowland South America

No abstract provided.

Evaluation Of Immune-Modulating Therapies For Parkinson's Disease, Katherine E. Olson

Theses & Dissertations

Parkinson’s disease (PD) is the second most common neurodegenerative

disorder, second only to Alzheimer’s disease (AD). It is characterized by a

progressive loss of dopaminergic neurons along the nigrostriatal axis and the

formation of proteinaceous inclusions of alpha-synuclein (α-syn). Secondary to

the loss of dopaminergic neurons is a progression in motor and non-motor

symptoms. Motor symptoms are characterized by slowness in movement,

stiffness and tremor. Non-motor symptoms include depression, constipation,

sleep abnormalities and loss of sense of smell. The cause of disease remains

incompletely understood. However, age, genetics, environment, viral infection,

and interplay between the innate and adaptive immune system …

Transcriptome Profiling Of Cleft Palate Intgf-Beta3 Knockout Mice Alleles: Rna-Seq Analysis Of Tgf-Beta3 Mice, Kelsey White

Theses & Dissertations

Background: Orofacial clefts are the most common craniofacial birth defect with a complex, combinatorial etiology. Tgf-b3 regulates palatal fusion in mice; Tgf-b3 knockout mice have cleft palate (CP) lacking other major deformities. The genes downstream of Tgf-b3 during palatogenesis remain largely unexplored. Our objective was to analyze the global transcriptome changes and their contribution to CP and identify novel Tgf-b3 associated genes involved in formation of CP. We used RNA-sequencing to analyze and compare the whole transcriptome of Tgf-b3 alleles during palatal growth and fusion in mice.

Results: …

Risk Of Post-Ercp Pancreatitis In Liver Transplant Patients: Single Center Experience, Shailender Singh

Theses & Dissertations

Introduction: Acute pancreatitis remains the most common severe complication of endoscopic retrograde cholangiopancreatography (ERCP). The exact cause of post-ERCP pancreatitis (PEP) is unclear. Regardless of the mechanism that initiates PEP, the pathways of inflammation are similar to other forms of acute pancreatitis and include the activation of various inflammatory cytokines, released from the acinar cells and subsequently from helper T lymphocytes and macrophages. Liver transplants (LTx) patients on immunosuppressive medications have impaired T-cell response and hence decreased ability to generate these cytokines. The aim of this study was to review incidence rates and risk factors of PEP in this …

A Translational Evaluation Of Renewal Of Inappropriate Mealtime Behavior, Vivian Ibañez, Cathleen C. Piazza, Kathryn M. Peterson

Theses & Dissertations

The term renewal describes the recurrence of previously extinguished behavior that occurs when the intervention context changes. Renewal has important clinical relevance as a paradigm for studying treatment relapse because context changes are necessary for generalization and maintenance of most intervention outcomes (Podlesnik, Kelley, Jimenez-Gomez, & Bouton, 2017). The effect of context changes are particularly important during intervention for children with feeding disorders because children eat in a variety of contexts, and extinction is an empirically supported and often necessary intervention. Therefore, we used an ABA arrangement to test for renewal during intervention with 3 children diagnosed with a feeding …

The Effect Of Mechanical Vibration On Pain And Rate Of Tooth Movement During Initial Orthodontic Alignment, Leslie Ellingson

Theses & Dissertations

Purpose: The purpose of this investigation was to evaluate the effect of mechanical vibration on pain experienced and rate of tooth movement (OTM) during the initial alignment phase of orthodontic treatment.

Materials and Methods: Participants were randomly allocated to control, low frequency or high frequency. An electric toothbrush was modified to provide high frequency vibration. A low frequency vibration device was acquired from a commercial vendor. Experimental groups applied vibration to the dentition for 20 minutes daily. All participants completed questionnaires using visual analog scales at five time points. Pain experience was measured in millimeters (mm) with the scale measuring …

Role Of Transforming Growth Factor (Tgf) – Β Signaling In Craniofacial Development, Malignancies And Regeneration, Jingpeng Liu

Theses & Dissertations

The transforming growth factor (TGF) – β signaling pathway regulates a diversity of fundamental cellular processes such as cell growth and proliferation, cell differentiation, migration, apoptosis and other biological functions, both during embryogenesis and in adult tissue homeostasis. TGF-β is known to play a critical role in palatal development as in TGF-β knockout murine models, TGF-β deficiency causes cleft palate, a common craniofacial deformity in humans due to the abnormality of growth, elevation or fusion of the two palatal shelves. In order to investigate the mechanisms of how TGF-β regulates palatogenesis, we generated TGF-β3 knockout (-/-) murine models, performed systematic …