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Ecg Quiz, Chollada Buranakarl, Saikaew Sutayatram, Chutamas Benjanirut

The Thai Journal of Veterinary Medicine

A 14-year-old neutered female mixed breed dog weighing 12 kg was admitted at the in-patient unit of The Small Animal Teaching Hospital, Chulalongkorn University in October 2017 with clinical signs of depressed, anorexia, weakness and continuous vomiting. However, no sign of abdominal pain was found. History taking showed that the dog had gait disorientation due to central nervous system disorder. The dog also had murmur heart sound graded IV/VI without sign of cardiac disease since June 2017. The echocardiogram was performed which the results showed that the dog had moderate degenerative mitral valve disease (DMVD) with mild tricuspid regurgitation. The …

Implementation And Verification Of A Synthetic Eddy Method (Sem) In The Eagle3d Compressible Flow Solver, Patrick Kopper

Doctoral Dissertations and Master's Theses

The objective of this thesis is to implement and evaluate a Synthetic Eddy Method (SEM) into the Eagle3D compressible flow solver. Both the ability of Eagle3D to resolve unsteady turbulent ow field and capability of the SEM to reproduce given Reynolds stress profiles to start realistic turbulent behavior are verified using common academic cases. Eagle3D is a Computational Fluid Dynamics (CFD) solver using a novel combination of a Bounded Central Differencing (BCD) scheme with Weighted Essentially Non-Oscillatory (WENO) approximation to reduce numerical dissipation. SEM is a modern synthetic turbulence method able to reproduce an arbitrary Reynolds stresses specification on discretionary …

Evaluating The Effect Of Contextual Variables On Discounting Of Health Related Behaviors, Jessica Hubrich

Theses

The present study used a discounting task with differing contextual variables to examine how variables effect discounting between studies and future health related behaviors. Thirty nine participants completed two discounting questionnaires, each included hypothetical food choices paired with a weight loss or stable weight. Participants were instructed to complete each survey based on either their current weight or a gain of 75 pounds, and each survey included two identical hypothetical menu options. One menu incorporated low calorie foods, while the other incorporated moderately healthy foods, and participants were instructed to select the menu they preferred based on weight loss/no weight …

Raising Sex Trafficking Awareness Among School Nurses, Johanna Mccollum

Senior Honors Theses

Sex trafficking, a type of human trafficking, has become a public health concern. Sex trafficking is taking place on a large scale in the United States. Children in the United States are at greatest risk. Raising the awareness of healthcare providers about sex trafficking is imperative. An unsung hero that may hold the keys to this awareness in the healthcare profession is the school nurse. The school nurse is trained in many areas, and upholds practice standards, but sex trafficking is not currently included in their repertoire. As nurses, they already hold a trusted position. With education, proper resources, and …

Identifying Emotional Intelligence And Metacognition In Medical Education, Robert Weigand

All Theses And Dissertations

An extensive literature review identified emotional intelligence and metacognition had not been examined in medical education as integrated concepts in the reflective practice of medical residents. Continued research into the independent application of these concepts in medical education maintains a perspective that has permeated medical literature for 20 years. Research into emotional intelligence and metacognitive functioning and its’ influence on reflective practice in medical education acknowledges the need for more taxonomies of knowledge and skills. A quantitative correlational study was conducted utilizing Family Practice residents. Three valid and reliable assessment tools identified as the MSCEIT, MAI and Groningen were used …

Gmos, Genetically Modified Organisms Or Genuinely Mixed Opinions? A Reasonable Consumer's Understanding Of The Terms “Gmo” And “Non-Gmo,” And The Struggle To Set A Standard, Nicholas J. Kromka

Seton Hall Law Review

No abstract provided.

The Specifications And Ingredients Found In Commercially Available Toothpastes, Kalyan C. Gundavarapu, Srinivas S. Ramachandra, Daniel D. Dicksit, Vivek V. Gupta

Makara Journal of Health Research

Background: The aim of this study was to evaluate the specifications and ingredients of various commercially available toothpastes in Malaysia. Methods: Various toothpaste brand samples were collected from malls & pharmacies in Petaling Jaya, Malaysia. Each brand was studied and information regarding the presence or absence of fluoride, the fluoride content, whether the fluoride content was displayed on the packaging, the type of fluoride present, and the country of manufacture was noted. Using this information, a comprehensive list of commercially available toothpastes in the Malaysian market was prepared. Results: the 57 toothpastes collected, 12.3% (n = 7) did not state …

The Effect Of Flaxseed Ethanolic Extract On The Structure Of The Kidney And The Endocrine Pancreas In Streptozotocin Induced Diabetic Rats, Imad Matloub Al-Ani, Ghassan A. Al-Ani, Marwan S. Azzubaidi, Basma I. Al-Ahmed

Makara Journal of Health Research

Background: The present investigation has been designed to study the possible protective effect of flaxseed extract on the structures of the endocrine pancreas and kidneys of streptozotocin (STZ) induced diabetic rats for 30 days. Methods: Forty male Sprague-Dawley rats were randomized into five groups (n = 8). Normal control group (NC); received distilled water orally, normal flaxseed group (NF); treated orally with (400 mg/kg) extract of flaxseed, diabetic control group (DC); treated with single intraperitoneal dose of STZ (60 mg/kg), diabetic flaxseed group (DF); diabetic rats treated with extract of flaxseed (400 mg/kg), diabetic glibenclamide group (DG); diabetic rats treated …

Sex Differences In Collateral Remodeling Following Hindlimb Arterial Occlusion, Laura Burckhardt

Master's Theses

Clinical evidence indicates a higher incidence of peripheral arterial occlusive disease and associated likelihood of critical limb ischemia in women, as well as worse prognosis and decreased survival post myocardial infarction. Therefore, understanding the possible differences in underlying vascular compensation mechanisms is crucial. With arterial occlusions, necrosis and tissue injury can be naturally mitigated by the collateral circulation, improving patient prognosis. Previous sex-comparison studies describing differences in vascular remodeling are inconsistent. Therefore, the aim of this study was to describe the effect of arterial occlusion on collateral remodeling in healthy male and healthy reproductive-stage female mice. At 7 days following …

Survival And Capture Efficiency Of River Otters In Southern Illinois, Andrew U. Rutter

Theses

River otter (Lontra canadensis) populations in Illinois have rebounded considerably after >80 years of harvest protection and a successful reintroduction program. However, few studies of river otter ecology exist in the Midwestern U.S. where river otter numbers have increased in recent decades. Capturing study animals safely and efficiently is a critical part of wildlife research, and difficulties associated with live capture of river otters have contributed to the dearth of research on the species. Furthermore, estimating survival rates and identifying causes of mortality are important in effectively managing river otters. To address these knowledge gaps, my objectives were determine survival …

Oystower | Oystown Multi-Scalar Biomimetic Design For Resilient Coastal Inhabitation, Christopher William James

Honors Capstones

No abstract provided.

The Effects Of Equine Assisted Leadership Programs On Perceived Professional Development Outcomes, Leighanne Pentecost

Doctoral Dissertations and Projects

The purpose of this causal-comparative study was to compare the mean scores of the survey instrument to determine if there were statistically significant differences between the mean pre-test and post-test scores of perceived professional development obtained by participants of the Equine Assisted Learning leadership programs. The participants in the study were chosen by a convenience sampling method. The sample in the study is comprised of 36 members from three (3) EAL leadership programs selected from North Carolina, Ohio, and California. The Leader Attributes Inventory was used to collect pre-test and post-test data from each participant in the study. The paired …

Mitochondrial Fission After Traumatic Brain Injury, Tara Fischer

Dissertations and Theses (Open Access)

Mitochondrial dysfunction is a central feature in the pathophysiology of Traumatic Brain Injury (TBI). Loss of mitochondrial function disrupts normal cellular processes in the brain, as well as impedes the ability for repair and recovery, creating a vicious cycle that perpetuates damage after injury. To maintain metabolic homeostasis and cellular health, mitochondria constantly undergo regulated processes of fusion and fission and functionally adapt to changes in the cellular environment. An imbalance of these processes can disrupt the ability for mitochondria to functionally meet the metabolic needs of the cell, therefore resulting in mitochondrial damage and eventual cell death. Excessive fission, …

Memory Potential, Molecular Characterization, And Translational Applications Of The Novel Theo/Tceo T Cell Phenotype, Todd Bartkowiak, Todd Bartkowiak

Dissertations and Theses (Open Access)

T cells comprise a substantial arm of the immune system and are exquisitely adapted to combat pathogens and tumors. The inflammatory environment largely dictates the nature of T cell response. A hallmark of T cell-mediated immunity is formation of immunological memory; the ability to respond more potently to re-encounter with pathogens. The immune system is also capable of recognizing tumors as foreign, much like viral or bacterial pathogens. Tumors have evolved, though, to generate an immunosuppressive environment to avoid destruction. The field of immunotherapy seeks to overcome immune suppression, in part by targeting T cell co-receptors on the cell surface …

Dynamic Assessment Of Nk Cell Interactions With Pediatric Tumor Cells To Predict Response To Immunotherapy, Arianexys Aquino Lopez

Dissertations and Theses (Open Access)

Due to Natural Killer (NK) cells’ capacity to target tumor cells without prior sensitization, adoptive NK cell therapy represents a promising immunotherapy approach for pediatric cancer patients. Our laboratory has developed an NK cell expansion protocol that generates large quantities of NK cells for therapeutic infusion. Given that NK cells are heterogeneous, with variable receptor expression and potential to target tumor cells, the purpose of my study was to determine whether subpopulations of NK cells with enhanced anti-tumor potential could be identified for increased potency of the NK cell infusion product. In addition, we previously showed that our expanded NK …

Characterization Of Notch1 And Pi3k-Pten-Akt/Mtor Pathway Interaction In Head And Neck Squamous Cell Carcinoma, Kyriante' Henry

Dissertations and Theses (Open Access)

Head and neck squamous cell carcinoma (HNSCC) affects various mucosal sites of the upper aerodigestive tract, including the nasal and oral cavities, the nasopharynx, and the oropharynx. More than five hundred thousand new cases of HNSCC occurred in 2011 alone, with 50,000 reported cases in the United States. This trend made HNSCC the seventh most common non-skin cancer worldwide (Ferlay et al., 2015). Although significant epidemiological and pathological advancements have been made, survival rates have not improved much over the last 40 years, leaving a mortality rate that remains at approximately 50%. An unbiased drug screen demonstrated that HNSCC cell …

Circulating Autoantibodies In Human Traumatic Spinal Cord Injury Subjects And Their Relationship To The Development Of Neuropathic Pain, Georgene Hergenroeder

Dissertations and Theses (Open Access)

Background:

Approximately 17,500 spinal cord injuries (SCI) occur yearly in the U.S. causing considerable morbidity and mortality. Neuropathic pain (NP) ensues in 40-70% of SCI. An autoimmune response resulting from disruption of the blood-spinal cord-barrier may be a contributor to NP. However, the relationship between autoantibodies and NP after SCI in humans has not been thoroughly characterized nor have autoantigens been identified. Glial fibrillary acidic protein (GFAP) and collapsin response mediator protein2 (CRMP2) were identified as candidate autoantigens. The hypothesis is that proteins from the injured spinal cord released by SCI trigger autoantibody production which can lead to the development …

Modeling Post Stroke Respiratory Dysfunction, Apneas And Cognitive Decline, Anthony Patrizz

Dissertations and Theses (Open Access)

Modeling Post Stroke Respiratory Dysfunction,

Apneas and Cognitive Decline

Anthony Patrizz, B.A.

Advisory Professor: Louise McCullough M.D., Ph.D.

Stroke is a major cause of mortality and the leading cause of long-term disability in the US. More than 60% of individuals suffering a first time stroke develop respiratory dysfunction, prolonging recovery and increasing mortality. Post-stroke cognitive decline is a major contributor to disability and nursing home placement, therefore the cognitive consequences of Stroke Induced Respiratory Dysfunction (SIRD) need to be explored if we hope to enhance functional recovery. The first step towards treatment of the negative consequences of SIRD is the …

Insights Into The Therapeutic Potential Of Salt Inducible Kinase 1: A Novel Mechanism Of Metabolic Control, Randi Fitzgibbon

Dissertations and Theses (Open Access)

Salt inducible kinase 1 (SIK1) has been considered a stress-inducible kinase since it was first cloned in 1999. Continued efforts since this time have been dedicated to characterizing the structure and function of SIK1. Such research has laid the ground work for our understanding of SIK1 action and regulation in tissue and stimuli dependent manners. The fundamental findings of this dissertation continue in this tradition and include investigations of SIK1 regulatory mechanisms in skeletal muscle cells, the cellular and physiological effects of SIK1 loss of function in vitro and in vivo, and intracellular metabolic and mitochondrial regulation by this …

Cytoplasmic Cyclin E Mediates Resistance To Aromatase Inhibitors In Breast Cancer, Iman Doostan

Dissertations and Theses (Open Access)

Almost seventy percent of patients with breast cancer have tumors that express hormone receptors and need hormonal therapy. Aromatase inhibitors (AIs) block estrogen biosynthesis and are considered as the first line hormonal therapy for ER⁺ post-menopausal patients. However, resistance to these drugs remains a major challenge in clinic and the biology of such resistance is not completely understood. Cyclin E is deregulated in breast cancer through generation of low molecular weight isoforms that renders patients to a poor survival. Herein, we show that HR+ patients with LMW-E expressing tumors show diminished early response to neo-adjuvant AIs as well as …

Endocytic Trafficking Of The Amyloid Precursor Protein In Rat Cortical Neurons, Sahily Reyes

Dissertations and Theses (Open Access)

Amyloid-beta (Aβ) aggregation and deposition into extracellular plaques is a hallmark of the most common forms of dementia, including Alzheimer’s disease. The Aβ-containing plaques result from pathogenic cleavage of amyloid precursor protein (APP) by secretases resulting in intracellular production of Aβ peptides that are secreted and accumulate extracellularly. Despite considerable progress towards understanding APP processing and Aβ aggregation, the mechanisms underlying endosomal production of Aβ peptides and their secretion remain unclear. Using endosomes isolated from cultured primary neurons, we determined that the trafficking of APP from the endosomal membrane into internal vesicles of late endosome/multivesicular bodies (MVB) is dependent on …

Membrane Bound Il21 Promotes Natural Killer Cell Expansion Through Mir 124-3p Mediated Regulation, Anitha Somanchi

Dissertations and Theses (Open Access)

Natural Killer (NK) cells are cells of the innate immune system that act as first line of defense against viral infections and participate in tumor immune surveillance. NK cells do not cause graft versus host disease (GvHD), or require prior antigen exposure to exert anti-tumor activity, hence are an attractive choice for immunotherapy applications. Owing to small numbers of NK cells in peripheral blood (1-32%, with a 6% median), ex vivo expansion of NK cells is critical for NK cell adoptive immunotherapy, various expansion platforms have been explored over the decades. We developed a robust platform for ex vivo expansion …

Investigating If Multidisciplinary Or Homogenous Teams Are More Innovative In A Higher Education Setting, Blake Howard Hoover

Theses and Dissertations

This study is derived from the claim that multidisciplinary groups are more innovative than homogeneous groups; a claim that has flooded the business industry and has become criteria for accreditation in higher education. However, the impact of disciplinary diversity in work groups is a growing area of research; therefore, it is yet to be thoroughly understood. The purpose of this study is to answer the question: are multidisciplinary teams more innovative than homogenous teams. To accomplish this university students from differing majors were sorted into multidisciplinary and homogeneous groups while participating in a two-day innovation course. The course taught the …

Association Between Latent Toxoplasma Gondii Infection And Alzheimer's Disease, Cynthia Elizabeth Wyman

Theses and Dissertations

Introduction: Many studies have found an association between Toxoplasma gondii seropositivity and behavioral and cognitive changes in animal models and in humans. In addition, early findings have suggested an association between T. gondii seropositivity and Alzheimer's disease (AD). We sought to determine whether there is an association between T. gondii seropositivity and AD as well as cognitive functioning (including memory, working memory, processing speed, language functioning, executive functioning) in a large, well-characterized sample of subjects with AD and matched controls without dementia. Method: Using ELISA assays, we determined anti-T. gondii IgG antibody titers in 114 control subjects and in …

Transforming (Perceived) Rigidity In Environmental Law Through Adaptive Governance, J.B. A. Ruhl, Hannah Gosnell, Brian C. Chaffin, Craig A. Arnold, Et Al.

Vanderbilt Law School Faculty Publications

The Endangered Species Act (ESA) is often portrayed as a major source of instability and crisis in river basins of the U. S. West, where the needs of listed fish species frequently clash with agriculture dependent on federal irrigation projects subject to ESA Section 7 prohibitions on federal agency actions likely to jeopardize listed species or adversely modify critical habitat. Scholarship on Section 7 characterizes the process as unwaveringly rigid, the legal hammer forcing federal agencies to consider endangered species needs when proposing operations and management plans for federally funded irrigation. In this paper, we identify barriers to an integrated …

Online Learning In Biology: An Investigation Into Designing Online Learning Resources, William Ford

Electronic Theses and Dissertations

As technology continues to advance, many instructors are incorporating online activities into their courses. While online learning has several benefits, there is still debate on how instructors can best develop and utilize these resources in their classroom. This study is split into two smaller projects that both aim to provide further insights on how to develop online activities that target undergraduate biology students. The first project revealed that elaborative feedback in a phylogenetic activity was more useful for students who had some exposure to phylogenetics prior to completing the activity. The results of the second project revealed that the appearance …

Teacher Perceptions Of Using Positive Behavior Interventions And Supports As Behavioral Interventions In A Pre-K-5 Elementary School: A Phenomenological Study, Meghann Roberts-Clawson

Electronic Theses and Dissertations

Teachers’ Perceptions of Using Positive Behavior Interventions and Supports as Behavioral Interventions in a Pre-K-5 Elementary School: A Phenomenological Study by Meghann E. Roberts-Clawson This qualitative study addresses teacher perceptions of using positive behavior interventions and supports (PBIS) as positive behavioral interventions. This phenomenological study was conducted within a Pre-K-5 elementary school in northwestern North Carolina. In order to collect qualitative data, personal individualized interviews were conducted from a purposeful sample of teachers in the school who have experience implementing more intensive positive behavioral interventions. By analyzing data derived from the interviews and classroom and individualized documentation, the researcher was …

Design And Validation Of A Scale For Preschoolers: Measuring Nutrition Knowledge, Beliefs, And Behaviors, Michelle E. Johnson

Electronic Theses and Dissertations

The literature indicates a lack of validated scales to measure nutrition knowledge, attitudes and behaviors in preschool-aged children. Reliable and valid assessment tools are critical in the development of nutritional interventions for young children; careful design, including psychometric evaluation of reliability and validity, is the best approach to scale development. Best practice points to an efficient, yet comprehensive look at the constructs of knowledge, attitudes, and behaviors. This multi-phase study included 298 preschool children ages 2-6 years (151 girls, 147 boys; mean age 3.936). A 45-item scale was created, with 4 subscales to measure the nutrition knowledge, attitudes, and behaviors …

The Effects Of A Supermarket Tour On Improvement Of Nutrition Knowledge And Eating Behavior, Elizabeth Hall

Electronic Theses and Dissertations

The purpose of this study was to determine if participation in a supermarket tour improves nutrition knowledge and eating behavior in adult participants. Participants were recruited in communities surrounding Food City stores, a local supermarket. Prior to completing a standardized tour, participants completed a survey to assess nutrition knowledge and eating behavior. This survey was given to participants again three months later. A program evaluation was given one time at the end of the tour. Data analysis revealed no significant findings, other than the behavior-based question: “How many meals or snacks on most days included vegetables”. Vegetable consumption appeared to …

Thinking Before You Act: A Constructive Logic Approach To Crafting Performance-For- Development Narrative, Angela Duggins

Electronic Theses and Dissertations

The intent of this thesis was to test the feasibility of constructing performance-for-development narrative using a constructive logic approach. I created an equation which expressed the sum of non-human-elements as the sum of a narrative with each element serving as a variable. I used a review of persuasion literature to provide insight into the selection and manipulation of each variable. I provided my family as a hypothetical example and used my knowledge of their preferences and communication styles in conjunction with the literature and the equation to craft a narrative which might increase pro-school attitudes in other families like my …