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Zika Virus Encoding Nonglycosylated Envelope Protein Is Attenuated And Defective In Neuroinvasion, Arun Saravanakumar Annamalai, Aryamav Pattnaik, Bikash R. Sahoo, Ezhumalai Muthukrishnan, Sathish Kumar Natarajan, David Steffen, Hiep Vu, Gustavo A. Delhon, Fernando Osorio, Thomas M. Petro, Shi-Hua Xiang, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

ABSTRACT Zika virus (ZIKV), a mosquito-transmitted flavivirus responsible for sporadic outbreaks of mild and febrile illness in Africa and Asia, reemerged in the last decade causing serious human diseases, including microcephaly, congenital malformations, and Guillain-Barré syndrome. Although genomic and phylogenetic analyses suggest that genetic evolution may have led to the enhanced virulence of ZIKV, experimental evidence supporting the role of specific genetic changes in virulence is currently lacking. One sequence motif, VNDT, containing an N-linked glycosylation site in the envelope (E) protein, is polymorphic; it is absent in many of the African isolates but present in all isolates from the …

Setback Distance Requirements For Removal Of Swine Slurry Constituents In Runoff, John E. Gilley, Shannon L. Bartelt-Hunt, Kent M. Eskridge, Xu Li, Amy M. Schmidt, Daniel D. Snow

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The use of setback distances for manure application on cropland areas adjacent to surface water bodies could serve a function similar to vegetative filter strips. However, little information currently exists to identify the setback distances necessary to effectively reduce the transport of contaminants in runoff. The objective of this study was to determine the effects of setback distance and runoff rate on concentrations of selected constituents in runoff following land application of swine slurry to a no-till cropland area in southeast Nebraska. The study site had a residue cover of 7.73 Mg ha-1 and a slope gradient of 4.9%. The …

Beneficial Effects Of Specific Natural Substances On Oral Health, Sameer Shaikh, S. Manoj Kumar

Saudi Medical Journal

Substances that are consumed daily or occasionally may influence an individual’s oral health. Some substances, such as alcohol, tobacco, and areca nut, adversely affect the oral region. However, some other substances, such as honey and green tea, which have antimicrobial properties, and berries, which have anticarcinogenic potential, exhibit beneficial effects on oral health. The effectiveness of synthetic drugs in maintaining oral health cannot be ignored; however, the benefits of synthetic drugs are associated with adverse effects and high costs. By contrast, the medicinal use of natural substances is associated with safety, affordability, and long-term benefits. In this paper, we review …

Fatal Butane Toxicity And Delayed Onset Of Refractory Ventricular Fibrillation, Khalid N. Almulhim

Saudi Medical Journal

A 30-year-old male was presented to the Emergency Department (ED) by the Emergency Medical Services (EMS). He was found unconscious but breathing normally, and had a seizure for more than 30 minutes. He was no previous history of systemic disease, previous operation, medication and any known allergy. According to the witnesses, he was alone in the coffee shop, and besides him was a lighter refill canister containing 250 ml extra purified butane gas, and he suddenly collapsed and had seizure. Six hours later, he developed ventricular fibrillation and he was not responding to amiodarone infusion, and 4 times defibrillation and …

Discovery, Research, And Development Of New Antibiotics: The Who Priority List Of Antibiotic-Resistant Bacteria And Tuberculosis, Evelina Tacconelli, Elena Carrara, Alessia Savoldi, Stephan Harbarth, Marc Mendelson, Dominique L. Monnet, Celine Pulcini, Gunnar Kahlmeter, Jan Kluytmans, Yehuda Carmeli, Marc Ouellette, Kevin Outterson, Jean Patel, Marco Cavaleri, Edward M. Cox, Chris R. Houchens, M Lindsay Grayson, Paul Hansen, Nalini Singh, Ursula Theuretzbacher, Nicola Magrini, Who Pathogens Priority List Working Group

Faculty Scholarship

Summary

Background The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and mortality worldwide. Due to its large public health and societal implications, multidrug-resistant tuberculosis has been long regarded by WHO as a global priority for investment in new drugs. In 2016, WHO was requested by member states to create a priority list of other antibiotic-resistant bacteria to support research and development of effective drugs.

Methods We used a multicriteria decision analysis method to prioritise antibiotic-resistant bacteria; this method involved the identification of relevant criteria to assess priority against which each antibiotic-resistant bacterium was rated. The final priority …

Bridging The Gap Between Technology Usage In The Construction Industry And In The Classroom, Marco Maffioli

Construction Management

As construction begins to advance more and more every day, technology is one of the most volatile aspects due to its ever changing nature. Technology, and all the software’s that encompass it, is the future of this industry and if we want to keep improving and growing as an industry we need to better align our future new hires with the most prevalent technology and that starts in the classroom. Specifically, the Construction Management Department at Cal Poly, San Luis Obispo, one of the most advanced in Nation, still struggles to align with the expectations and reality of the CM …

Comparison Study Between Post-Fermentation Stillage And Pre-Fermentation Mash Utilizing Acidification And Steam Explosion Techniques For Cellulose Saccharification, Daniel Mckee

Master's Theses

Pre-fermentation mash fiber and post-distillation stillage fiber were examined and compared using a variety of preparatory techniques to determine the better source for cellulose fiber saccharification. Once screened, dried, and diluted to a 10% solution, mash fiber and stillage fiber were exposed to increasing temperatures for steam explosion techniques as well as increasing acidification techniques. Both underwent enzymatic saccharification to convert the exposed cellulose to glucose and other sugars. Once the optimum steam explosion technique parameters and acidification parameters were determined to be 2.5% sulfuric acid at 127.8°C for 1 hour, a comparison of the saccharification of pre-fermentation mash fiber …

Effects Of Temperature On Growth And Molting In Blue Crabs (Callinectes Sapidus) And Lesser Blue Crabs (Callinectes Similis), Abigail Ann Kuhn

Master's Theses

Temperature can exert impacts on many processes in ectotherms. With global temperatures rising due to climate change, many ectothermic species may exhibit changes in growth rates and size at maturity, and these changes can have population-level effects. Predicting responses of species to climate change will require not only knowledge of thermal tolerance limits, but also effects of temperature change on growth rates and other life history parameters. For arthropods that exhibit discontinuous growth (i.e., molting), this includes both intermolt period and growth per molt. Previous laboratory and field experiments suggest that temperature affects both intermolt period (IMP) and growth per …

The Public’S Perception Of Humanlike Robots: Online Social Commentary Reflects An Appearance-Based Uncanny Valley, A General Fear Of A “Technology Takeover”, And The Unabashed Sexualization Of Female-Gendered Robots, Megan K. Strait, Cynthia Aguillon, Virginia Contreras, Noemi Garcia

Computer Science Faculty Publications

Towards understanding the public’s perception of humanlike robots, we examined commentary on 24 YouTube videos depicting social robots ranging in human similarity – from Honda’s Asimo to Hiroshi Ishiguro’s Geminoids. In particular, we investigated how people have responded to the emergence of highly humanlike robots (e.g., Bina48) in contrast to those with more prototypically-“robotic” appearances (e.g., Asimo), coding the frequency at which the uncanny valley versus fears of replacement and/or a “technology takeover” arise in online discourse based on the robot’s appearance. Here we found that, consistent with Masahiro Mori’s theory of the uncanny valley, people’s commentary reflected an aversion …

Apan Production Through Photooxidation Of Isoprene In The Presence Of NoX, Timothy Glidewell

Masters Theses

Peroxyacyl nitrates (PANs, RC(O)OONO₂) are of great importance in atmospheric chemistry. They act as transporters of reactive nitrogen, and radical delivery agents. There are no known natural emission sources of PANs; they are produced through reaction of volatile organic compounds (VOCs) and nitrogen oxides (NO_x) in the atmosphere.

VOCs can enter the atmosphere through biogenic and anthropogenic pathways. It has been estimated that isoprene makes up 70% of the biogenic VOCs (BVOCs) emitted annually. Isoprene has been shown to impact ozone levels in both rural and urban areas by sequestering and transporting NO_x in the form …

Better Fit: A Conceptual Solution For Seamless Exercise Experience, Hongwei Huang

Theses

The development of fitness technology has changed the way we exercise over time, and each technology has allowed people to exercise independently in various ways, such as wearable devices, fitness apps, game consoles, and even social media. The consequence is that more people get used to exercising solely with their digital device and get motivated from virtual communities rather than in a real environment. However, the research shows there can be even more benefit for people by exercising with others in a physical space.

The thesis utilizes UX design methodologies to develop a seamless-workout experience that enables a user to …

Black Behind The Ear: Using Motion Graphics To Encourage Self-Awareness And Embrace Racial Heritage., Carolina Lopez

Theses

Black Behind the Ear is an animated visual representation of Elizabeth Acevedo’s poem “Hair”. This poem uses hair as a metaphorical element to represent the internalized racism and racial amnesia predominant in the Dominican Republic, a place that owes African slaves for much of the island’s racial, and cultural heritage.

This motion graphics piece intends to encourage self-awareness in a time when embracing one’s culture and race can break the ossified schemes passed through generations about personality standards based on physical attributes. Understanding where one comes from helps people see why certain ideas are worth standing for, and consequently results …

Camera Obscura, Dan Latourette

Theses

Camera Obscura is a feature-length script about a 19th-century photographer who must document the unraveling Civil War while struggling to come to terms with deaths of his loved ones. It is a historical fiction film about memory, death, and human costs.

Rutherford Holding, an adept yet recluse photographer, stands between a mobilizing country bound for war and the trauma of losing his loved ones years ago. As those around him enlist and prepare in nationalistic fervor for what is to be the American Civil War, Holding desires to evade any chance to meet death face-to-face once again. However, he pigeonholes …

The Soul’S Speaker: Give Your Eyes Some Rest, Fuye Zhang

Theses

The students studying in colleges often fix their eyes on books, on computer screens and archives for a long time to gain knowledge. As a result of this, their eyeballs often turn red out of fatigue. Researches have shown that college students lack the awareness of the benefits of giving their eyes some rest. However, there are few of eye protection advertisements which suggest the need for students to give their eyes some rest. As a designer, I need to let people know the important roles that eyes play in the human body. I feel it is important for designers …

Audialtext: Improving Communication Accessibility For The Deaf Through Automatic Voice-Recognition And Wearable Smart-Technology., Ernest Roszkowski

Theses

Whether you are ordering food at a restaurant, asking for directions, or receiving a phone call from a family member, it is apparent that human communication is an important part of everyday life. Those who are deaf have limited communication accessibility compared to their hearing counterparts, and by default, obtain less public information and face more obstacles during social interactions.

This thesis project will attempt to bridge this communication gap through the exploration of human interactions with user interface (UI) and user experience (UX) design. The goal is to design and develop an application concept for wearable smart-technology that will …

Abyss, Manojh Reddy

Theses

“When the human civilization continues to pursue its darker deeds, the wrong doings, the dark demons in every individual, the rage we show towards Mother Nature is the path to the end of the entire civilization. And, that end will not come with a bang, but with a whimper “ - Manojh Reddy

A Microdebitage Analysis Of The Winterville Mounds Site (22ws500), Stephanie Leigh-Ann Guest

Master's Theses

The Winterville Mounds site (22WS500) was a civic ceremonial center of 23 mounds and is located near Greenville in northwest Mississippi. Winterville excavations as field schools are ongoing since 2005 under the direction of Dr. H. Edwin Jackson of The University of Southern Mississippi. Examination of the >1/4" (6.35 mm) mesh screened lithic material provided mixed results of reduction stages and lacked variety of non-local materials (Guest 2006, Winter 2009, McClendon 2012). Authors of these analyses called for the examination of the 1/16” (1.58 mm) water-screened lithic material to identify reduction stages and traces of non-local materials to provide evidence …

A Neuroprotective Role For Mir-1017, A Non-Canonical Mirna, Matthew De Cruz

Master's Theses

miRNAs are post-transcriptional regulators of gene expression, with numerous being involved in neurobiology. Within the human genome a quarter of the identified miRNA loci derive from a class of miRNAs termed tailed mirtrons. Despite the identification of this large population of miRNA, no functional studies have been conducted to identify their role. In this study we examined the highly expressed and deeply conserved Drosophila 3’ tail mirtron, miR-1017, as a candidate to elucidate tailed mirtron functionality. We identified acetylcholine receptor transcripts, Da5 and Da2, as bona fide targets for miR-1017. Interestingly, Da2 is also the host transcript for miR-1017. We …

Impacts Of Oil Exposure During Early Life Development Stages In Sheepshead Minnows (Cyprinodon Variegatus) Under Different Environmental Factors, Danielle Simning

Master's Theses

The release of approximately 5 million barrels of crude oil into the northern Gulf of Mexico during the 2010 Deepwater Horizon oil spill jeopardized estuarine ecosystem health from Texas to Florida. These estuarine habitats, which serve as nurseries for many important fisheries are also prone to rapid fluctuations in environmental stressors such as oxygen concentration, and salinity. The consequence of combined exposure to crude oil and suboptimal environmental factors during early life stage development of fish is still largely unknown. The objective of this project was to investigate the impacts of exposure to crude oil in combination with varying environmental …

The Uniform Soybean Tests: Northern Region 2017, Gary L. Nowling, Guohong Cai

Uniform Soybean Tests Northern Region

United States Department of Agriculture Agricultural Research Service, West Lafayette, Indiana, Cooperating with State Agricultural Experiment Stations, Northern States.

Chicken Feet, Simone Louie

Gandy Dancer Archives

No abstract provided.

Webbed, Laurie J. Jackson

Gandy Dancer Archives

No abstract provided.

Hablando De Negocios: Three Rio Grande Valley Businesses During The Great Depression, 1929-1939, Karla A. Lira

Theses and Dissertations

The Rio Grande Valley is in the South most tip of Texas and borders Northern Mexico, it includes Willacy, Cameron, Hidalgo, and Starr Counties. Scholars have focused on gender, agriculture, and labor of the area. However, historians have failed to research the region through a business perspective during the Great Depression. This thesis then seeks to analyze ways in which the Great Depression affected the Rio Grande Valley through the research of two stores and one business in the area: The Manuel Guerra Store, Edelstein’s furniture store, and John Shary’s land selling business. Its objective will fill an existing gap …

American Equal Protection And Global Convergence, Holning Lau, Hillary Li

Fordham Law Review

Commentators have noted that equal protection doctrine is in a state of transformation. The nature of that transformation, however, is poorly understood. This Article offers a clearer view of the change underway. This Article is the first to reveal and synthesize three major trajectories along which the U.S. Supreme Court has begun to move. First, the Court has begun to blur the line that it previously drew between facial discrimination and disparate impact. Second, the Court has begun to collapse its previously established tiered standards for reviewing discrimination. These two trajectories combine to produce a third trajectory of change: by …

Attitudes And Perceived Legitimacy Of Police: Crises, Responses, And How Race Influences Perceptions, Brigitte Bonaci

Theses and Dissertations

Public relations is a strategic field because an organization may need to structure a message with the intent of persuading the public and making it respond to a crisis and a message in a certain way. This study will help introduce the concept of a lingering crisis that is hardly present in research and could be put under the public relations umbrella. Using a survey of communications students, this study will compare the public attitudes and perceptions of perceived legitimacy of a police department after it experiences one of three crisis types, one of which being a lingering crisis. Attitudes …

Sensitivity Of Facial Organs Of Pythons As Deduced By Radiation Heat Transfer Analysis Under Varying Environmental Conditions, Rama Wairagkar

Theses and Dissertations

Predicting the behavior of snakes has been an interest to several scientists for the last few decades. Even though considerable amount of research has been carried out pertaining to snakes, there remains a degree of curiosity regarding their striking ability, live prey detection at locations where visual clues are unobtainable, thermosensation and the phenomena that drives these conducts. Researches carried out so far have moderately disregarded the perception of sensitivity of facial pits of snakes and its characteristics under contrasting temperature domains. This thesis attempts to undertake a computational analysis of the sensitivity of facial pits of Burmese pythons under …

5-Oxo-Ete Antagonists In Allergic Disease; Design And Synthesis Of Affinity Chromatography Ligand For 5-Hedh; And Synthesis Of Isoprostanes As An Index For The Diagnosis In Alzheimer’S Disease, Qiuji Ye

Theses and Dissertations

Arachidonic acid (AA, 4, Figure 1) is a 20:4 (ω-6) fatty acid with a 20-carbon chain and four cis-double bonds, and the esterified form of AA in phospholipids can be enzymatically liberated by phospholipases (PL) and subsequently metabolized into a variety of physiologically important mediators known as eicosanoids (Figure 2). One of the most important eicosanoids is 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE, 17). The 5-oxo-ETE (17) is the most known potent chemotactic factors for human eosinophils, and it can stimulate the late-phase asthma attacks.¹ To determine how the biosynthesis of 5-oxo-ETE is regulated, so as to determine its pathophysiological roles in the …

Predatory Capacity Of King Crabs In Antarctica, Brittan V. Steffel

Theses and Dissertations

For millions of years, cold water temperatures have excluded shell-crushing (durophagous) predators from continental-shelf environments off the western Antarctic Peninsula. Recently, however, king crabs, Paralomis birsteini, have been found in dense, reproductively viable populations on the upper continental slope, and rapid warming might enable them to expand to the shelf. King crabs are crushing shelled invertebrates on the slope, but calcification of sturdy, shell-crushing chelae is likely inhibited by the low saturation state of high-Mg calcite in the deep Southern Ocean. The objectives of this study were to better understand the predatory capacity of P. birsteini by estimating the potential …

A Survey Of Quality Of Oils Used In Thai Pig Farms, Alongkot Boonsoongnern, Prapassorn Boonsoongnern, Pichai Jirawattanapong, Nattavut Rattanavanichroj, Pariwat Poolperm

The Thai Journal of Veterinary Medicine

Oil is commonly added into pig diets to increase energy in animal feed formulation. Fifty-eight oil samples: 1) crude coconut oil (n=11), 2) crude palm oil (n=6), 3) refined palm oil (n=6), 4) crude soybean oil (n=4), 5) refined soybean oil (n=5), 6) crude rice bran oil (n=6), 7) crude chicken oil (n=6), 8) crude lard (n=5) and 9) used oil (n=9) from pig farms, feed mills and traders in Thailand were collected and analyzed for quality by measurement of pH, percentage of total polar compounds (% TPC), peroxide value (PV), free fatty acid (FFA), iodine value (IV), percentage of …

Investigation Into Antimicrobial Resistance, Enterotoxin And Cassette Chromosome Gene Of Staphylococcus Aureus Isolates From Humans, Cows And Goats In Taiwan, Chi-Shih Chu, Han Hsiang Huang, Shou-Heng Chiang, Chi-Chung Chou, Jyh-Mirn Lai, Wen-Ling Shih, Chih-Hsuan Changchien, Heng-Ching Lin, Shih-Te Chuang, Yao-Chi Su

The Thai Journal of Veterinary Medicine

Multidrug-resistant Staphylococcus aureus (MDR S. aureus) is predominately present in humans and animals. Staphylococcal enterotoxin (SE) is one of the representative toxins produced by S. aureus. The drug resistance patterns, presence of eighteen SE genes and staphylococcal cassette chromosome (SCCmec) in S. aureus strains isolated from human cellulitis, septicemia, mastitis and farmed ruminant mastitis were investigated and analyzed. Methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) accounted for 51.35% (76/148) and 48.65% (72/148), respectively. Both MSSA and MRSA carried sea (15%), seb (30.8%) and sek (27.5%) genes. Eighty percent of the MRSA strains (52/65) belonged to SCCmec types I, …