Digital Commons Network^™

On Workaholism: Do Parental Work Behaviors Predict The Work Behaviors Of Undergraduates?, Jesse A. Wingate

Theses and Dissertations

This cross-sectional study examined the associations among perceived parental behavior and personality on work behaviors of undergraduate students from a large Southeastern university. Past research suggests that children who perceive their parents to be workaholics are more likely to exhibit workaholic behavior themselves (Chamberlin & Zhang, 2009). Moreover, personality factors including conscientiousness and neuroticism, have been categorized as antecedents of workaholic behavior in previous studies (Andreassen, Hetland, & Pallesen, 2010; Aziz & Tronzo, 2011; Burke, Matthiesen, & Pallesen, 2006). Students (N = 209) completed questionnaires assessing Big Five personality factors, dispositional optimism, and perceptions of parental work drive, parental …

Exploring The Concept Of Human Oct3 Inhibitors As A Novel Class Of Antidepressants, Kavita A. Iyer

Theses and Dissertations

The Dukat laboratory developed 2-amino-6-chloro-3,4-dihydroquinazoline (A6CDQ) as a 5-HT₃ receptor ligand. A6CDQ and one of its positional isomers, the 7-chloro analog A7CDQ, produced antidepressant-like effects in the mouse tail suspension test (TST). We investigated and systematically ruled out a solely 5-HT₃ receptor or hSERT mediated mechanism of antidepressant-like effect for both A6CDQ and A7CDQ.

The role of organic cation transporter 3 (OCT3) as an alternative mechanism in the regulation of neurotransmitters including serotonin (5-HT) and the therapeutic potential of targeting hOCT3 to achieve antidepressant effects has been established. By virtue of possessing protonatable nitrogen atoms, 2-aminodihyroquinazolines could potentially …

Exploring The Role Of Intersectionality On Cardiovascular Disease Risk In Sexual Minorities, Leia Harper

Theses and Dissertations

Background: Previous research has shown that sexual minority individuals (SM) are twice as likely to smoke, twice as likely to be overweight or obese, and less likely to be physically active than heterosexual persons; all of which place SMs at an increased risk for cardiovascular disease (CVD). While information on CVD risk by race/ethnicity and socioeconomic status is well documented, there is scant literature examining race, gender, and the potential CVD risk in SMs. The purpose of this study was to examine CVD risk in sexual minorities.

Method: The current study used data from the National Longitudinal Study of Adolescent …

Is Your Student Fit For That College? A Study Of The Factors That Contribute To Students’ Academic Performance In College, Abdulaziz A. Alotaibi

Theses and Dissertations

The purpose of this study was to expand the extent of available literature in regard to the factors that contribute to students’ academic performance in college. It focused on a neglected segment of the student population, which is Saudi Arabian students studying in the United States. This study utilized a nonexperimental quantitative research design in order to investigate the relationship between the independent variables (the characteristics of the student, the characteristics of the program, and the academic and social integration between the student and the program) and the dependent variables (degree GPA, ability to graduate within academic program time frame, …

Dietary Adaptations And Intra- And Interspecific Variation In Dental Occlusal Shape In Hominin And Non-Hominin Primates, Kelsey O'Neill

Theses and Dissertations

Dental morphology and tooth shape have been used to recreate the

dietary adaptations for extinct species, and thus dental variation can provide

information on the relationship between fossil species and their

paleoenvironments. Variation in living species with known behaviors can provide

a baseline for interpreting morphology, and behavior, in the fossil record.

Tooth occlusal surface outlines in hominins and non-hominin primates, and other

mammals, have been used for assessments of taxonomic significance, with

variability often considered as being primarily phylogenetic. Few studies have

attempted to assess how diet might influence the pattern of variability in closely

related species. Here the …

Role Of Vav2 In Podocyte Inflammasome Activation And Glomerular Injury During Hyperhomocysteinemia, Sabena Conley

Theses and Dissertations

Hyperhomocysteinemia (hHcys) is a widely known pathogenic factor in the progression of end-stage renal disease (ESRD) and it is also associated with an increased risk for injurious cardiovascular pathologies during ESRD. HHcys is linked to the formation and activation of the NOD-like receptor protein 3 (NLRP3) inflammasome, characterized as a critical early mechanism initiating the inflammatory response. NADPH oxidase (NOX)-derived reactive oxygen species (ROS) mediate the activation of the NLRP3 inflammasome in podocytes in response to elevated levels of homocysteine (Hcys) in vitro and in vivo. However, it remains unknown how NLRP3 inflammasome activation is triggered by NOX. The …

The Effects Of Tidal Forcing On Nutrient Fluxes In The Tidal, Freshwater James River Estuary, Va, Dana L. Devore

Theses and Dissertations

A 12-month study (January to December 2015) focused on the effects of tidal forcing on nutrient fluxes in the tidal, freshwater segment of the James River Estuary (JRE). Discrete sampling of nutrient chemistry and continuous monitoring of tidal discharge were used to determine the volume and timing of the tides, and differences in nutrient concentrations between incoming and outgoing tides. The goal of this study was to improve understanding of tidal influence on nutrient fluxes and their role in nutrient transport to the lower estuary. Results suggested that differences in nutrient concentrations between incoming and outgoing tides were small throughout …

Dimension Reduction And Variable Selection, Hossein Moradi Rekabdarkolaee

Theses and Dissertations

High-dimensional data are becoming increasingly available as data collection technology advances. Over the last decade, significant developments have been taking place in high-dimensional data analysis, driven primarily by a wide range of applications in many fields such as genomics, signal processing, and environmental studies. Statistical techniques such as dimension reduction and variable selection play important roles in high dimensional data analysis. Sufficient dimension reduction provides a way to find the reduced space of the original space without a parametric model. This method has been widely applied in many scientific fields such as genetics, brain imaging analysis, econometrics, environmental sciences, etc. …

Measurement Of Rare Earth And Uranium Elements Using Laser-Induced Breakdown Spectroscopy (Libs) In An Aerosol System For Nuclear Safeguards Applications, Ammon N. Williams

Theses and Dissertations

The primary objective of this research is to develop an applied technology and provide an assessment for remotely measuring and analyzing the real time or near real time concentrations of used nuclear fuel (UNF) elements in electrorefiners (ER). Here, Laser-Induced Breakdown Spectroscopy (LIBS) in UNF pyroprocessing facilities was investigated. LIBS is an elemental analysis method, which is based on the emission from plasma generated by focusing a laser beam into the medium. This technology has been reported to be applicable in solids, liquids (includes molten metals), and gases for detecting elements of special nuclear materials. The advantages of applying the …

Laser Vaporization Controlled Condensation And Laser Irradiation In Solution For The Synthesis Of Supported Nanoparticle Catalysts, Vitaly Kisurin Mr.

Theses and Dissertations

Solid catalyst supports of SiOx-RGO (Reduced Graphene Oxide) and UiO-67 (Universitet i Oslo) have been successfully synthesized and were loaded with palladium nanoparticles to test for a series of heterogeneous reactions. The SiOx/RGO catalysts were synthesized through laser ablation of silicon and graphite oxide micron powder and UiO-67 metal-organic framework (MOF) was synthesized through mixing of precursors with DMF/HCl solution and washing the resultant powder from impurities. The SiOx/RGO supports were later impregnated with palladium precursors which were then subject to Microwave Irradiation (MWI). The UiO-67 framework was impregnated with palladium precursors and was irradiated with pulsed Nd:YAG 532 nm …

What’S Real? What’S Not? : Reality Tv’S Effect On Relational Aggression Among Black College Women, Ashley N. Hill

Theses and Dissertations

Relational aggression, behaviors that manipulate social relationships, is a pressing issue among Black college women (Dahlen, Czar, Prather, & Dyess, 2013). As a result of experiencing and using relational aggression, Black women may experience diminished interpersonal interactions and poorer overall psychological well-being (Gomes, Davis, Baker, & Servonsky, 2009). The present study examined how Black reality television (BRTV) models relationally aggressive behaviors for viewers. According to Cultivation theory, television has the power to influence the social reality (i.e. attitudes and perceptions) of individuals who consume high amounts of television (Gerbner et al, 2002), while Identification theory suggests that deep cognitive and …

Optimizing Virtual Machine I/O Performance In Cloud Environments, Tao Lu

Theses and Dissertations

Maintaining closeness between data sources and data consumers is crucial for workload I/O performance. In cloud environments, this kind of closeness can be violated by system administrative events and storage architecture barriers. VM migration events are frequent in cloud environments. VM migration changes VM runtime inter-connection or cache contexts, significantly degrading VM I/O performance. Virtualization is the backbone of cloud platforms. I/O virtualization adds additional hops to workload data access path, prolonging I/O latencies. I/O virtualization overheads cap the throughput of high-speed storage devices and imposes high CPU utilizations and energy consumptions to cloud infrastructures. To maintain the closeness between …

Nostalgia And Iphone Camera Apps: An Ethnographic Visual Approach To Iphoneography, Maria L. De Panbehchi

Theses and Dissertations

The iPhone is the most popular smartphone and camera on social media. iPhoneography, the photography taken or edited with the iPhone, has set the trend of nostalgic photography on social media during the 2010s; thus, the iPhone, a high-tech camera, produces low-tech-looking images. This dissertation attempts to find out why iPhone photographers (iPhoneographers) take, edit, and share images that mimic photographs taken with analog photographic equipment. I argue that nostalgia allows iPhoneographers to use the iPhone as a creative tool and to belong to a community. Based on the arguments of Vilém Flusser—who suggested that photographers are more interested in …

Beyond The Single Story: How Analog Hypertext Facilitates Representation Of Multiple Critical Perspectives In An Art Museum Object Study Gallery, Aimee D. Hunt

Theses and Dissertations

This project utilized a form of arts based educational research described as analog hypertext to develop interpretative material representing multiple critical, theoretical, and disciplinary perspectives on objects in a university art museum’s object study gallery. Drawing on scholars’ recommendations for postcolonial interpretation of non-Western art, the project created a web of information, which simultaneously revealed and critiqued the underlying ideologies and power structures shaping the museum’s display in an effort to change existing interpretive practice. The project developed five color-coded thematic self-guided tours—art as commodity, spiritual practice, technology and cultural evolutionism, mortuary rituals, and postcolonial perspectives—presented to the public as …

Valuing Natural Space And Landscape Fragmentation In Richmond, Va, Lee Wyatt Carpenter

Theses and Dissertations

Hedonic pricing methods and GIS (Geographic Information Systems) were used to evaluate relationships between sale price of single family homes and landscape fragmentation and natural land cover. Spatial regression analyses found that sale prices increase as landscapes become less fragmented and the amount of natural land cover around a home increases. The projected growth in population and employment in the Richmond, Virginia region and subsequent increases in land development and landscape fragmentation presents a challenge to sustaining intact healthy ecosystems in the Richmond region. Spatial regression analyses helped illuminate how land cover patterns influence sale prices and landscape patterns that …

Improved Capability Of A Computational Foot/Ankle Model Using Artificial Neural Networks, Ruchi D. Chande

Theses and Dissertations

Computational joint models provide insight into the biomechanical function of human joints. Through both deformable and rigid body modeling, the structure-function relationship governing joint behavior is better understood, and subsequently, knowledge regarding normal, diseased, and/or injured function is garnered. Given the utility of these computational models, it is imperative to supply them with appropriate inputs such that model function is representative of true joint function. In these models, Magnetic Resonance Imaging (MRI) or Computerized Tomography (CT) scans and literature inform the bony anatomy and mechanical properties of muscle and ligamentous tissues, respectively. In the case of the latter, literature reports …

Eeg Interictal Spike Detection Using Artificial Neural Networks, Howard J. Carey Iii

Theses and Dissertations

Epilepsy is a neurological disease causing seizures in its victims and affects approximately 50 million people worldwide. Successful treatment is dependent upon correct identification of the origin of the seizures within the brain. To achieve this, electroencephalograms (EEGs) are used to measure a patient’s brainwaves. This EEG data must be manually analyzed to identify interictal spikes that emanate from the afflicted region of the brain. This process can take a neurologist more than a week and a half per patient. This thesis presents a method to extract and process the interictal spikes in a patient, and use them to reduce …

The Role Of Matrix Metalloproteinase 9 And Osteopontin In Synaptogenesis And Reinnervation Of The Olfactory Bulb Following Brain Injury, Melissa A. Powell

Theses and Dissertations

Traumatic brain injury (TBI) is a serious health concern, causing cognitive, motor, and sensory deficits, including olfactory dysfunction. This dissertation explores the effects of TBI on synaptic plasticity within the olfactory system, seeking to define mechanisms guiding postinjury sensory reinnervation. Physical forces induced by TBI can axotomize olfactory receptor neurons (ORNs), which innervate olfactory bulb (OB). These axons regenerate OB projections after injury, a process involving growth through a complex extracellular matrix (ECM). As such, we investigated a potential molecular mechanism capable of modifying local OB ECM to support postinjury synaptogenesis. Since matrix metalloproteinases (MMPs) and their ECM substrates are …

Characterization Of Poly(Dimethylsiloxane) Blends And Fabrication Of Soft Micropillar Arrays For Force Detection, Thomas J. Petet Jr

Theses and Dissertations

Diseases involving fibrosis cause tens of thousands of deaths per year in the US alone. These diseases are characterized by a large amount of extracellular matrix, causing stiff abnormal tissues that may not function correctly. To take steps towards curing these diseases, a fundamental understanding of how cells interact with their substrate and how mechanical forces alter signaling pathways is vital. Studying the mechanobiology of cells and the interaction between a cell and its extracellular matrix can help explain the mechanisms behind stem cell differentiation, cell migration, and metastasis. Due to the correlation between force, extracellular matrix assembly, and substrate …

The Care Factor: The Importance Of Using Domain Identification Measures To Identify Stereotype Threat Vulnerability In High School Females, Kimberly Y. Randolph

Theses and Dissertations

Abstract

THE CARE FACTOR: THE IMPORTANCE OF USING DOMAIN IDENTIFICATION MEASURES TO IDENTIFY STEREOTYPE THREAT VULNERABILITY IN HIGH SCHOOL FEMALES.

By Kimberly Y. Randolph, PhD

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University.

Virginia Commonwealth University, 2016.

Major Director: Dr. Charol Shakeshaft, PhD. Professor Department of Educational Leadership

There is a gap that persists in math achievement between high school males and females. Although the NAEP 2015 longitudinal report shows a narrowing in math achievement between males and females there still remains a gap. More importantly, females are …

Forest Stand Structure And Primary Production In Relation To Ecosystem Development, Disturbance, And Canopy Composition, Cynthia M. Scheuermann

Theses and Dissertations

Temperate forests are complex ecosystems that sequester carbon (C) in biomass. C storage is related to ecosystem-scale forest structure, changing over succession, disturbance, and with community composition. We quantified ecosystem biological and physical structure in two forest chronosequences varying in disturbance intensity, and three late successional functional types to examine how multiple structural expressions relate to ecosystem C cycling. We quantified C cycling as wood net primary production (NPP), ecosystem structure as Simpson’s Index, and physical structure as leaf quantity (LAI) and arrangement (rugosity), examining how wood NPP-structure relates to light distribution and use-efficiency. Relationships between structural attributes of biodiversity, …

Design And Development Of A High-Temperature High-Pressure Rolling Ball Viscometer/Densimeter And Evaluation Of Star Polymer-Solvent Mixtures, Matthew Stanton Newkirk

Theses and Dissertations

Modern automotive applications such as transmission clutch plates, combustion chambers, diesel fuel injector tips, and axle gears and friction plates operate at temperatures that can exceed 250°C and pressures of 40,000 psia. Industrial practice is to add homopolymers and copolymers to base oils to modify bulk fluid viscosity and frictional properties for these demanding applications. However, designing polymeric additives for lubricants and predicting their performance is limited by the lack of available high-temperature high-pressure (HTHP) viscosity and density data needed to test contemporary lubricity models. Thus, a major objective of this thesis is the design, development, and commissioning of a …

Longitudinal Relations Between Parental Messages Supporting Fighting And Aggressive Behavior In Early Adolescence: The Moderating Role Of Positive Parenting Practices, Megan M. Carlson

Theses and Dissertations

The prevalence of physical aggression increases during adolescence and is associated with negative health outcomes. It is important to identify risk and protective processes for adolescent aggression in the context of the parent-adolescent relationship. The current study examined the potential moderating role of positive parenting at Wave 1 on relations between perceived parental messages supporting fighting at Wave 1 and adolescent aggression based on parent- and student-report at Wave 2. Participants included a sample of 537 adolescents and their primary caregivers, recruited from four sites in the U.S. No significant moderating effects were found. However, parental messages supporting fighting were …

Adjustment Profiles Among Youth In Diverse Cultural Contexts: Individual, Family, And Contextual Influences, Alicia Borre

Theses and Dissertations

Recent literature has noted that not all youth who experience adverse circumstances (e.g. poverty, exposure to violence, maltreatment) end up displaying expected unfavorable outcomes (e.g. academic failure, depression, drug dependence); in fact, some youth display “resilience,” broadly understood as adaptive functioning in the face of adversity (Luthar, Cicchetti, & Becker, 2000). Overall, research on resilience has offered a new approach to the study of at-risk populations, emphasizing the study of strengths, processes, and mechanisms among individuals and communities that may favor positive adaptation, rather than emphasizing deficits among those experiencing adversity (Schoon, 2012). Although resilience research has come a long …

The Role Of Enteric Glia In Opioid-Induced Constipation, Sukhada Bhave

Theses and Dissertations

Morphine is one of the most widely used drugs for the treatment of pain but its clinical efficacy is limited by adverse effects including persistent constipation and colonic inflammation. Morphine-induced colonic inflammation is facilitated by microbial dysbiosis and bacterial translocation. In this study, we demonstrate that secondary inflammation and persistent constipation are modulated by enteric glia. In chronic morphine treated mice (75 mg morphine pellet/5 days), ATP-induced currents were significantly enhanced in enteric glia isolated from the mouse colon myenteric plexus. Chronic morphine resulted in significant disruption of the colonic epithelium and increased Il-1β in the myenteric plexus. The increase …

An Investigation Of Kinetic Visual Biofeedback On Dynamic Stance Symmetry, Trisha J. Massenzo

Theses and Dissertations

The intent of the following research is to utilize task-specific, constraint-induced therapies and apply towards dynamic training for symmetrical balance. Modifications to an elliptical trainer were made to both measure weight distributions during dynamic stance as well as provide kinetic biofeedback through a man-machine interface. Following a review of the background, which includes research from several decades that are seminal to current studies, a design review is discussed to cover the design of the modified elliptical (Chapter 2).

An initial study was conducted in a healthy sample population in order to determine the best visual biofeedback representation by comparing different …

Exploring Predictors Of Teamwork Performance In An Interprofessional Education Setting, Danah Alsane, Patricia Slattum W. Slattum

Theses and Dissertations

Abstract

EXPLORING PREDICTORS OF TEAMWORK PERFORMANCE IN AN INTERPROFESSIONAL EDUCATION SETTING

By Danah M. Alsane, MS.

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Pharmaceutical Science at Virginia Commonwealth University

Virginia Commonwealth University, 2016

Advisor: Patricia Slattum, Pharm.D., Ph.D.

Professor and Director of the Geriatric Pharmacotherapy Program

Department of Pharmacotherapy and Outcomes Science

Objectives: The primary objective of this study was to explain how individual characteristics influence teamwork development. In addition, it evaluated how teamwork development, in conjunction with content knowledge, impact students’ performance on a team-based project in an Interprofessional Quality Improvement …

Joint Detection-State Estimation And Secure Signal Processing, Mengqi Ren

Theses and Dissertations

In this dissertation, joint detection-state estimation and secure signal processing are studied. Detection and state estimation are two important research topics in surveillance systems. The detection problems investigated in this dissertation include object detection and fault detection. The goal of object detection is to determine the presence or absence of an object under measurement uncertainty. The aim of fault detection is to determine whether or not the measurements are provided by faulty sensors. State estimation is to estimate the states of moving objects from measurements with random measurement noise or disturbance, which typically consist of their positions and velocities over …

Investigating The Role Of The Nucleosome Remodeling Factor Ino80 In Development And Nurf In Anti-Tumor Immunity, Zeinab Abdallah Elsayed Ms

Theses and Dissertations

Understanding how an epigenetic regulator such as ATP-dependent chromatin-remodeling complexes modulate processes such as development and/or immune response is essential for our comprehension of cell biology. Deletion of the ATP-dependent chromatin remodeling factor INO80 is known to be embryonically lethal, however, the mechanism is not known. To identify roles for INO80 in mouse early development we generated Ino80 KO mice. Ino80 KO ESCs (Embryonic stem cells) were viable when maintained at ground state pluripotency but fail to differentiate in vitro and in vivo. Gene expression analysis of Ino80 KO early embryos by in situ hybridization showed elevated Bmp4 expression …

Wreading, Performing, And Reflecting: The Application Of Narrative Hypertext And Virtual World Experiences To Social Work Education, Linda Ayscue Gupta Phd

Theses and Dissertations

In this dissertation I propose the use of a new media composition of narrative hypertext, performances in a virtual world, and a dialogic process of writing to provide a continuum of learning opportunities in social work education. I suggest that the structure of the hypertext narrative, embedded with hypermedia, mirrors the dissociative aspects of traumatic memory. I argue that work with the multivocality and multisequentiality of narrative hypertext emulates the process of discovery in the clinical interview. The immersive component of work in a virtual world deepens the realism and affective impact of simulations and creates opportunities to practice and …