Digital Commons Network^™

Examining Genetic And Environmental Influences On Alcohol Use And Externalizing Behaviors In African American Adolescents, Neeru Goyal

Theses and Dissertations

The aim of this thesis is to expand our understanding of the etiology of alcohol misuse and related disorders in African Americans using genetically informative study designs. Specifically, we take advantage of the candidate-gene approach and polygenic score analysis to extend the literature specific to African American populations. Chapter 2 explores gene x environment (GxE) interactions through the candidate gene approach to explore the relationship between two genes chosen on their potential relevance to stress response and adolescent alcohol use and misuse, among African American youth living in highly impoverished neighborhoods, as moderated by stressful life events. Chapter 3 implements …

An Extension Of Penalized Ordinal Response Models, Qing Zhou

Theses and Dissertations

Ordinal responses are commonly seen in medical research. Many pathological evaluations and health status outcomes are reported on an ordinal scales. Some examples of ordinal outcomes include cancer stage (I, II, III and IV), or stage of liver disease (normal liver, chronic hepatitis, cirrhosis and end of stage liver disease or hepatocellular carcinoma (HCC)).

In recent years, there has been a demand to understanding the pathogenic association between ordinal clinical outcomes and molecular characteristics. Genomic characteristics are often assayed using a high-dimensional platform where the number of interrogated sites (P) exceeds the number of samples (n). Unfortunately, traditional ordinal response …

Perspectives, Beatrice Modisett

Theses and Dissertations

My paintings are linked to a thirst for exploring new landscapes and perspectives, my interest in the extremes and subtleties of geological phenomenon and a desire to create, chase after, and teeter on a brink. Here I will discuss these topics and work to unpack my interest in avoiding comfort, my relationship to control and the creation and function of my paintings. To extract myself from my tactile and visual world of process and paint and enter the world of written language presents very different challenges than the ones fostered in the studio. The goal in both is to reveal …

Collective Cadence, Alicia Dietz

Theses and Dissertations

Collective Cadence

Stories that start at birth,

end with death,

and include everything in-between.

A Medal of Honor recipient,

A mistake.

Morning coffee;

a late night call.

Whispered first names;

an off-key chorus;

deafening explosions;

silence.

One child playing;

another lifeless.

On the battlefield,

concealment is a survival skill.

Off that battlefield,

transparency enables survival.

Stories that shape the fabric of our experience

The threads that bind us

Through the telling of each,

we are united as one.

In the telling of the collective,

We find our own.

These are our stories.

This is our story.

I Reach Toward The Ground I Reach Toward Space, Kristen A. Sanders

Theses and Dissertations

Imagine one million and six hundred thousand years ago — a prehistoric character points. There in the moistened soil, the hominid Homo habilis draws a line, inscribing with her finger the first mark. At the core of my work is a meditation on this very scene as the otherwise unknowable origins of image making. And at the center of this discovery is a prehistoric woman — a previously invisible character within human evolution. My work aims to insert these characters into the origins of tool use, image making, and other supposed markers of humanness while also examining historical representations of …

Sweaty Mother Slow Groove, Devin Kylie Harclerode

Theses and Dissertations

Sweaty Mother Slow Groove is an engagement in magical thinking that proposes a displacement of swamp methodologies into the virtual realm, existing during the fourth wave. In doing so the cyborg and goddess are united in a re-routing of essentialism and the neo-liberal domination of technology. The metaphorical swamp is the possibility of a mushy danger zone that harnesses the absorption of an unwanted space: a disintegration of the binary and the soft-coded awareness of the body as a process, not a site.

Interhouse: A Place For Growing Up And Growing Adults, Nilufar Makhamatova

Theses and Dissertations

Society has become increasingly segregated by age which lessens the opportunities for communication between generations. Before the Internet, children and adolescents typically learned through traditional means - their parents, school teachers, and life experiences. Adults believed they were capable of recognizing and addressing the needs of children and adolescents. (Strom & Strom, 2012) Now, the global media is widely accessed by people of all ages which gives it the ability to influence a large population in different ways. This has led to children and adolescents being more heavily influenced and educated by the media than other traditional sources. Adolescents, in …

The Exchange: Curating Authenticity + Interaction, Sarah Webb

Theses and Dissertations

For a physical space to have an emotional impact on those who experience it, we must consider the connection and relationship between objects and experience, and how people make individual connections to insentient places. It is this symbiotic relationship that allows a building or space to attain a “soul”.

Through the adaptive re-use of a Richmond, Virginia building, this thesis project explores strategies of staging physical interaction and organic experiences through art and culture in the context of a mixed-use niche hotel.

Virtual / Reality: Designing Permeable Spaces For Social Well-Being In The Digital Age, Thomas R. Kennedy

Theses and Dissertations

The digital age has pushed people closer together than ever before. A device that fits in the palm of your hand allows instantaneous communication with billions of other human beings. People share everyday experiences, passing thoughts, personal photos, sometimes privately, often publicly. Distances between people and places feel reduced. Never has it been so easy to be so emotionally close to so many people.

But as digital experiences become routine, our collective perceptions of closeness and distance shift. As virtual communities become larger, so does our awareness of the actual distance between things. Even though humans can be genuinely close …

Heritage Hotel: A Marriage Of Heritage Tourism And Boutique Hospitality, Leah A. Embrey

Theses and Dissertations

As defined by Wai Mun Lim and Mel Endean in 2009 in their article “Elucidating the aesthetic and operational characteristics of UK boutique hotels” in the International Journal of Contemporary Hospitality Management, Boutique hotels have less than 100 rooms, have an individualistic and unique design, are often in historic buildings, and have highly personalized service for guests. I found that a boutique hotel that focuses on historic preservation and heritage tourism does four things. First, it respects the history of the building it is housed in, preserving as much of the original structure as possible. It also takes advantage of …

Boomerang Studio: Community Design For Action, Jessica Walton

Theses and Dissertations

An arts education space, focusing on concepts of design thinking aimed at providing low income middle and high school teens of color the opportunity to learn about interior design, architecture and crafts. Ultimately, Boomerang Studio hopes to engage students in the world of design as a means of creating greater diversity within these disciplines.

A City Winery - Revealing Process + Promoting Interaction, Eline Warren

Theses and Dissertations

This thesis project is an exploration of process in both design and winemaking. Wine has long been a part of Virginia’s history and culture and in recent years has influenced architecture and design that is specific to winemaking and hospitality. Through an interior intervention, this project addresses the many challenges of marrying production and hospitality design criteria under one roof. The final design encourages understanding of process through links between production and consumption with both a winemaking facility and laboratory that are integrated into the surrounding hospitality-oriented spaces. This visual exposure to the facility stimulates patron interest and intuitive knowledge …

It's Slapstick Design, Thanks! Wait! No "Thanks"- Just Slapstick Design ..., Curtis A. Bailey

Theses and Dissertations

I'm arguing for an approach to generating graphic form based on slapstick. Slapstick is a genre of physical comedy involving humorous portrayals of clumsiness, mistakes, and nonsense. I investigate it as an approach to form, content, process, and communication. These methods were used to construct an immersive installation loosely based on The Tibetan Book of the Dead.

Graphic design is expected to function. It does this by conditioning users to its particular patterns or by skillfully implementing familiar patterns. A slapstick approach to graphic design is valuable as a critical tool for disrupting conditioned experiences for promoting empathy by relating …

No Woman Is An Island, Adele Ball

Theses and Dissertations

We have gathered the following pages to archive our time here in Richmond, Virginia. We have been here for two years, growing slowly, moving when needed to new anchorholds to avoid detection or arrest. We scrutinize the urban environment like modern archeologists. We collect stories and speculate about new uses of old things. It is imperative to be resourceful here, and we do so out of necessity but also in the spirit of practice. These pages were made en route, each an exploration of the tools at hand when on the move. The method of creation is just as important …

"Fuck Off, Get Free, Love And Love's The Only Thing", David S. Moré

Theses and Dissertations

A child, angry at concrete and strip malls, enjoying coffee from too many styrofoam cups.

Loosely Bound, Alexander Martin

Theses and Dissertations

I take a poetic approach to graphic design practice. It is a subjectivist approach, which recognizes our human right to willful interpretation. Designers navigate form, culture, and history like poets through language. We are subjective, exploratory engines drawing formal inspiration from figural and analogical associations. Subjectivity in graphic design practice is complex, however. Subjectivity privileges the interaction between object and individual. When we designers interpret the literal world with the poet’s omni-directional sensitivity, we intentionally and intuitively create objects that accrete inexhaustible, extra-literal value for their audience.

Choreographic Space, Kelsey Sheaffer

Theses and Dissertations

This thesis, Choreographic Space, and accompanying exhibit is an arrangement of contemporary work being done in the cross-over between movement, drawing, sound and architecture. The thesis develops a lineage of choreographic thinking through a fissure in the classification of a dance as necessarily the body in motion. Through the link of the “choreographic object,” Choreographic Space asks how an interdisciplinary exploration of the principles of movement can reveal novel ways to think about the body in space.

The Curiosity Of Con, Petrified Breath, And An Accident Known As Blue., Steven Randall

Theses and Dissertations

My thesis installation emerged from an interest in visualizing breath. The resulting work came to exist at the intersection between art, biology, and performance.

The unicorn tapestries were used as a generative point of departure to explore the preservation and transformation of images through time, by time, and with time. Reproductions of the six tapestries were each etched into paper and then submerged into solutions of Phenol Red dye, Ferric Ferrocyanide (also known as Prussian Blue), and various forms of sodium chloride. Exhaled breath was used to encrust these images of the tapestries into physical objects which gradually crystallized and …

Design Thinking For The Development Of Formal Operations: A Team-Based Middle School Design Curriculum, Stephanie K. O'Dell

Theses and Dissertations

In this thesis, I propose a team-based design curriculum that aligns with the cognitive development of middle school age students. The ability to think abstractly develops at a specific time in development, according to widely accepted cognitive theory. The middle school years are the launching pad of abstract thinking. At this age, students are also primed for learning through social activity. The design process often includes abstract problem solving challenges, and working within a team structure. These ideas build a foundation for a research question—could a team-based design curriculum in middle school strengthen students’ natural cognitive development by providing opportunities …

A (Dis)Assemblage Of The Gallery-Growlery, Levester R. Williams

Theses and Dissertations

A (dis)Assemblage of the Gallery-Growlery exhibition and writing presents itself as a site of a morphological exploration of language, sound, and objects in tandem with the irreducibly venting black expression. Venting, the black expression never seeks wholeness within objects or language itself for it is a thing-in-itself. Its presence affords critical reception to a residue of delimiting forms. All growls eschew verbal objects for the manifestation of pure phonetics. A growl in a gallery is the growl. The growl resounds through the physicality of the objects and gallery. Also, it unwinds the object-among-objects as the phono-present stretches the discursive …

Monitor, Shana Hoehn

Theses and Dissertations

Descriptions of a scene interwoven with thoughts on how aesthetics sets behavioral expectations, observation as proof, views from a single perspective, casting of characters, spaces that evoke complicated histories, and my own history.

Fundamental Units, Ryan M. Flores

Theses and Dissertations

Surface, Skin, Facade, Countenance, Resistance, Chinchorro Mummies,Touch, Mark Making, Residue, Intuition, Repression, Indigestion, Disassemble, Blighted,Components, Body as Containers, Levels of Hierarchy, Absorption, Plastination, Modernism and Containment, Vanitas, Disembodied, Embodiment, Fragmentation, Arches, Gothic, Typology, Stacking of Cultures, Slippage.

Hybrid Straintronics-Spintronics: Energy-Efficient Non-Volatile Devices For Boolean And Non-Boolean Computation, Ayan K. Biswas

Theses and Dissertations

Research in future generation computing is focused on reducing energy dissipation while maintaining the switching speed in a binary operation to continue the current trend of increasing transistor-density according to Moore’s law. Unlike charge-based CMOS technology, spin-based nanomagnetic technology, based on switching bistable magnetization of single domain shape-anisotropic nanomagnets, has the potential to achieve ultralow energy dissipation due to the fact that no charge motion is directly involved in switching. However, switching of magnetization has not been any less dissipative than switching transistors because most magnet switching schemes involve generating a current to produce a magnetic field, or spin transfer …

Systematic Postsynthetic Modification Of Nanoporous Organic Frameworks And Their Performance Evaluation For Selective Co2 Capture, Timur Islamoglu

Theses and Dissertations

Porous organic polymers (POPs) with high physicochemical stability have attracted significant attention from the scientific community as promising platforms for small gas separation adsorbents. Although POPs have amorphous morphology in general, with the help of organic chemistry toolbox, ultrahigh surface area materials can be synthesized. In particular, nitrogen-rich POPs have been studied intensively due to their enhanced framework-CO₂ interactions. Postsynthetic modification (PSM) of POPs has been instrumental for incorporating different functional groups into the pores of POPs which would increase the CO₂ capture properties. We have shown that functionalizing the surface of POPs with nitro and amine groups …

Are You Covered? Examining How Knowledge Of The Patient Protection And Affordable Care Act Influences Use Of Preventive Reproductive Health Services, Ashlee Sawyer

Theses and Dissertations

The Patient Protection and Affordable Care Act (PPACA) expanded access to insurance coverage and health care services for many citizens, and has increased access for women in particular by including preventive reproductive health services as essential health benefits. The current national rates of sexually transmitted infections (STIs), reproductive cancer diagnoses, and unintended pregnancy serve as major areas of concern for women’s health and public health. The present study examined how knowledge of the PPACA influences receipt of preventive reproductive health services among women. Results indicate that higher levels of knowledge of the PPACA are associated with a greater likelihood of …

Death Vegas Valley, Eric M. Diehl

Theses and Dissertations

My work explores hallucinatory landscapes of the US American West by using a combination of painting styles outside of the Western painting canon. I cross-reference painting and cinema, interweaving video, acrylic paint and the panorama to create a satirical homage to the history and present state of the USA. However, through an earnest devotion to the medium - both painting and cinema - I find my criticisms also yearn to hold onto a belief in a myth I know to be false.

This is an American History conversation about artifice and consumerism through advertising. I use Las Vegas and the …

Telomere Length In Women With Breast Cancer: A Longitudinal Study Of Their Relationship To Chemotherapy And Acquired Psychoneurological Symptoms, Areej Alhareeri

Theses and Dissertations

Breast Cancer (BC) is one of the most commonly diagnosed malignancies in females. The 5-year survival rate for women with early stage BC is about 90%. However, the quality of life (QOL) for many of these women may be adversely affected due to treatment/cancer–related side effects, including a constellation of symptoms (anxiety, depression, pain, fatigue, sleep disturbance and depression), that are collectively termed psychoneurological symptoms (PNS). To gain insight into the contributory role of telomere length (TL) in the development and persistence of PNS, we have longitudinally studied 72 women (ages 23-71) with early stage BC (I-IIIA) at 5 time …

Truth And Doubt In Representation, Mathew Gasparek

Theses and Dissertations

My work deals with the connection between the act of representation and conceptions of truth in the contemporary image-mediated social environment. This thesis details elements of my paintings in exchange with methods and ideas from artists and writers in order to position my aesthetic and conceptual sensibilities within a historical and contemporary framework.

Momentum Clinic For Teen And Young Adult Cancer Patients, Merian O'Neil

Theses and Dissertations

This study explores the needs of teen and young adult cancer patients undergoing long-term chemotherapy treatments and the design of an outpatient clinic that accommodates this population’s unique needs. Most teens endure long-term treatments in a pediatric facility targeted primarily for children, while others are treated in adult facilities. Teens have different privacy and social needs than children, and while they are not adults, they are involved in their own treatment decisions, unlike children. The target age group for this study is teens and young adults, ages thirteen to twenty-two. A common theme emerged from research and interviews conducted in …

Novel Small Airway Model Using Electrospun Decellularized Lung Extracellular Matrix, Bethany M. Young

Theses and Dissertations

Chronic respiratory diseases affects many people worldwide with little known about the mechanisms diving the pathology, making it difficult to find a cure. Improving the understanding of smooth muscle and extracellular matrix (ECM) interaction is key to developing a remedy to this leading cause of death. With currently no relevant or controllable in vivo or in vitro model to investigate diseased and normal interactions of small airway components, the development of a physiologically relevant in vitro model with comparable cell attachment, signaling, and organization is necessary to develop new treatments for airway disease. The goal of this study is to …