Digital Commons Network^™

Using Creativity From Art And Engineering To Engage Students In Science, Mason Albert Kuhn, Scott Greenhalgh, Mark Mcdermott

Journal of STEM Arts, Crafts, and Constructions

STEAM education, referring to integrated Science, Technology, Engineering, Art, and Mathematics, is a contemporary buzzword that is popular in many schools. In particular, many elementary school teachers who have been tasked to incorporate STEM teaching, because of the requirements of the Next Generation Science Standards, attempt to apply the arts in their science curriculum because they feel more comfortable using instructional approaches that incorporate creative activities such as crafts, drawing, and model construction than the core practices of STEM disciplines. Teachers can use the creative arts activities in two ways to enhance the STEM learning environment: 1) Using creative processes …

Spatial Thinking Skills And Stem Connections: How Does This Issue Address Them?, Audrey C. Rule

Journal of STEM Arts, Crafts, and Constructions

In this editorial, the Editor considered the importance of spatial thinking skills to STEM careers, provided examples of ways scientists use spatial thinking, noted sex and socioeconomic differences in spatial skill proficiency, and reviewed ways that activities included in articles in this issue involved spatial thinking. Brief summaries and preview images were provided for the articles in the issue. The four-component spatial thinking classification scheme with categories of intrinsic-static, intrinsic-dynamic, extrinsic-static and extrinsic dynamic was applied to the activities from this issue of the Journal of STEM Arts, Crafts, and Constructions. All categories of this classification scheme were addressed, providing …

The Effect Of A Powered Ankle Foot Orthosis On Walking In A Stroke Subject: A Case Study, Ali Pourghasem, Ismail Ebrahimi Takamjani, Mohammad Taghi Karimi, Mohammad Kamali, Mohammad Jannesari, Iman Salafian

Department of Mechanical and Materials Engineering: Faculty Publications

[Purpose] Standing and walking are impaired in stroke patients. Therefore, assisted devices are required to restore their walking abilities. The ankle foot orthosis with an external powered source is a new type of orthosis. The aim of this study was to evaluate the performance of a powered ankle foot orthosis compared with unpowered orthoses in a stroke patient.

[Subjects and Methods] A single stroke subject participated in this study. The subject was fitted with three types of ankle foot orthosis (powered, posterior leg spring, and carbon ankle foot orthoses). He was asked to walk with and without the three types …

Parallel Technical Sessions Schedule, Institute Of Business Administration

International Conference on Marketing

No abstract provided.

Curran, Edward: Humanities Chairman Nomination Hearing (1985): Speech 06

Curran, Edward: Humanities Chairman Nomination Hearing (1985)

No abstract provided.

Finite Element Simulation And Additive Manufacturing Of Stiffness-Matched Niti Fixation Hardware For Mandibular Reconstruction Surgery, Ahmadreza Jahadakbar, Narges Shayesteh Moghaddam, Amirhesam Amerinatanzi, David Dean, Haluk E. Karaca, Mohammad Elahinia

Mechanical Engineering Faculty Publications

Process parameters and post-processing heat treatment techniques have been developed to produce both shape memory and superelastic NiTi using Additive Manufacturing. By introducing engineered porosity, the stiffness of NiTi can be tuned to the level closely matching cortical bone. Using additively manufactured porous superelastic NiTi, we have proposed the use of patient-specific, stiffness-matched fixation hardware, for mandible skeletal reconstructive surgery. Currently, Ti-6Al-4V is the most commonly used material for skeletal fixation devices. Although this material offers more than sufficient strength for immobilization during the bone healing process, the high stiffness of Ti-6Al-4V implants can cause stress shielding. In this paper, …

Computer Network Design For Universities In Developing Countries, Rafid Salih Sarhan Alsarhan

Information Technology Capstone Research Project Reports

The purpose of this project is to design a suitable network system for universities in developing countries. The aim was to design a network with high-quality security and low cost, in such a way that network devices of universities in developing countries, will meet standards associated with the universities in developed countries. This project will help to enhance education in developing countries. There are many devices that were used in designing the network, such as routers, switches, backup, firewall, and servers. All devices were connected to each other to make integration network system and configured by putting IP addresses to …

Tx-004hr Vaginal Estradiol Has Negligible To Very Low Systemic Absorption Of Estradiol., David F Archer, Ginger D Constantine, James A Simon, Harvey Kushner, Philip Mayer, Brian Bernick, Shelli Graham, Sebastian Mirkin, Rejoice Study Group.

Obstetrics and Gynecology Faculty Publications

OBJECTIVE: To evaluate the pharmacokinetics of TX-004HR vaginal estradiol softgel capsules when used for treating moderate-to-severe dyspareunia in postmenopausal women with vulvar and vaginal atrophy.

METHODS: A substudy of the REJOICE trial (multicenter, double-blind, placebo-controlled, phase 3) evaluated the pharmacokinetics of 4, 10, and 25-μg TX-004HR doses once/d for 2 weeks, followed by twice/wk for 10 weeks. Serum samples obtained at 2, 4, 6, 10, and 24 hours postdose on days 1 and 14, and once on day 84, were analyzed for area under the serum concentration-time curve, tmax, Cmin, Cavg, and Cmax for estradiol, estrone, and estrone conjugates.

RESULTS: …

Sirt1 Regulates Glial Progenitor Proliferation And Regeneration In White Matter After Neonatal Brain Injury., Beata Jablonska, Marcin Gierdalski, Li-Jin Chew, Teresa Hawley, Mackenzie Catron, Arturo Lichauco, Juan Cabrera-Luque, Tracy Yuen, David Rowitch, Vittorio Gallo

Pediatrics Faculty Publications

Regenerative processes in brain pathologies require the production of distinct neural cell populations from endogenous progenitor cells. We have previously demonstrated that oligodendrocyte progenitor cell (OPC) proliferation is crucial for oligodendrocyte (OL) regeneration in a mouse model of neonatal hypoxia (HX) that reproduces diffuse white matter injury (DWMI) of premature infants. Here we identify the histone deacetylase Sirt1 as a Cdk2 regulator in OPC proliferation and response to HX. HX enhances Sirt1 and Sirt1/Cdk2 complex formation through HIF1α activation. Sirt1 deacetylates retinoblastoma (Rb) in the Rb/E2F1 complex, leading to dissociation of E2F1 and enhanced OPC proliferation. Sirt1 knockdown in culture …

A Mineralized Alga And Acritarch Dominated Microbiota From The Tully Formation (Givetian) Of Pennsylvania, Usa, John A. Chamberlain Jr., Rebecca B. Chamberlain, James O. Brown

Publications and Research

Sphaeromorphic algal cysts, most probably of the prasinophyte Tasmanites, and acanthomorphic acritarch vesicles, most probably Solisphaeridium, occur in a single 20 cm thick bed of micritic limestone in the lower part of the Middle Devonian (Givetian) Tully Formation near Lock Haven, Pennsylvania. Specimens are composed of authigenic calcite and pyrite crystals about 5–10 µm in length. Some specimens are completely calcitic; some contain both pyrite and calcite; and many are composed totally of pyrite. The microfossils are about 80 to 150 µm in diameter. Many show signs of originally containing a flexible wall composed of at least two layers. Some …

The Vibrio Cholerae Minor Pilin Tcpb Initiates Assembly And Retraction Of The Toxin- Coregulated Pilus, Dixon Ng, Tony Harn, Tuba Altindal, Subramania Kolappan, Jarrad M. Marles, Rajan Lala, Ingrid Spielman, Yang Gao, Caitlyn A. Hauke, Gabriela Kovacikova, Zia Verjee, Ronald K. Taylor, Nicolas Biais, Lisa Craig

Publications and Research

Type IV pilus (T4P) systems are complex molecular machines that polymerize major pilin proteins into thin filaments displayed on bacterial surfaces. Pilus functions require rapid extension and depolymerization of the pilus, powered by the assembly and retraction ATPases, respectively. A set of low abundance minor pilins influences pilus dynamics by unknown mechanisms. The Vibrio cholerae toxin-coregulated pilus (TCP) is among the simplest of the T4P systems, having a single minor pilin TcpB and lacking a retraction ATPase. Here we show that TcpB, like its homolog CofB, initiates pilus assembly. TcpB co-localizes with the pili but at extremely low levels, equivalent …

Digital Literacies And Visual Rhetoric: Scaffolding A Meme-Based Assignment Sequence For Introductory Composition Classes, Andie Silva

Publications and Research

Introducing students to the practice of academic writing ideally goes beyond teaching strategies like drafting, outlining, and revising in order to encourage deeper skills such as critical thinking and metacognition. This post discusses an assignment series focusing on reflection, genre analysis, and multiliteracies leading up to the design of original memes.

Femininity And Feminism In Courtship In Eighteenth-Century Britain, Nicole Langevin

Honors Program Theses and Projects

No abstract provided.

Role Of The Endocannabinoid System And Medical Cannabis, Sabrina Jarvis, Sean Rasmussen, Blaine Winters

Student Works

Our bodies produce substances called endocannabinoids which attach to receptors within the endocannabinoid system (ECS) impacting physiological processes on a daily basis. The cannabis plant contains over 100 different cannabinoids which also manipulate the ECS. Knowledge about these interactions have led to an increase in cannabis based pharmacological studies. Providers should have a basic understanding about how the ECS works and how cannabis is being used to treat certain illnesses. This article presents what is currently known about the ECS and how cannabis based medicines impact it, as well as the current laws providers need know regarding cannabis use.

Sub-Cycle Ionization Dynamics Revealed By Trajectory Resolved, Elliptically-Driven High-Order Harmonic Generation, E. W. Larsen, S. Carlström, E. Lorek, C. M. Heyl, D. Paleček, K. J. Schafer, A. L'Huillier, D. Zigmantas, J. Mauritsson

Faculty Publications

The sub-cycle dynamics of electrons driven by strong laser fields is central to the emerging field of attosecond science. We demonstrate how the dynamics can be probed through high-order harmonic generation, where different trajectories leading to the same harmonic order are initiated at different times, thereby probing different field strengths. We find large differences between the trajectories with respect to both their sensitivity to driving field ellipticity and resonant enhancement. To accurately describe the ellipticity dependence of the long trajectory harmonics we must include a sub-cycle change of the initial velocity distribution of the electron and its excursion time. The …

The Impact Of Authentic Leadership Behavior On Employee Engagement And Organizational Ethical Culture In Nigeria, Adayehi B. Peter

Human Resource Development Theses and Dissertations

Authenticity in leadership is an old phenomenon that has recently sparked a new research interest in management and the human resource development (HRD) literature (Peus, Wesche, Streicher, Braun, & Frey, 2012). An upswing in highly publicized corporate scandals, management malfeasance, and broader societal challenges facing public and private organizations has contributed to the recent attention placed on authenticity and authentic leadership (Walumbwa, Avolio, Gardner, Wernsing, & Peterson, 2008). Authentic leadership behavior allows leaders and organizations meet the raised expectations of fairness, morality, and social responsibility held by employees and organizational stakeholders (Kiersch, 2012).

The primary purpose of this study was …

The Hif/Phf8/Ar Axis Promotes Prostate Cancer Progression., D Tong, Q Liu, G Liu, W Yuan, L Wang, Y Guo, W Lan, Dianzheng Zhang, S Dong, Y Wang, H Xiao, J Mu, C Mao, J Wong, J Jiang

PCOM Scholarly Works

Recent studies provide strong evidence that the androgen receptor (AR) signaling pathway remains active in castration-resistant prostate cancer (CRPC). However, the underlying mechanisms are not well understood. In this study, we demonstrate that plant homeo domain finger protein 8 (PHF8 )interacts with and functions as an essential histone demethylase activity-dependent AR coactivator. Furthermore, we demonstrate that the expression of PHF8 is induced by hypoxia in various prostate cancer cell lines. Knockdown of either hypoxia-inducible factor HIF2α or HIF1α almost completely abolished hypoxia-induced PHF8 expression. Importantly, we observed that PHF8 is highly expressed in clinical androgen deprived prostate cancer samples and …

Rowan Oak Attracts Visitors From 58 Countries, Christina Steube

University of Mississippi News

No abstract provided.

Laboratory Tests In The Development Of Wavecat, James Allen, Konstantinos Sampanis, Jian Wan, Deborah Greaves, Jon Miles, Gregorio Iglesias

School of Engineering, Computing and Mathematics

No abstract provided.

Week Of December 19, 2016, New York Medical College

InTouch

• Department of Surgery Hosts Thirteenth Annual Louis R.M. DelGuercio, M.D., Distinguished Visiting Professorship and Research Day
• Student Leadership Groups Take Action
• The First Snowman Project Is a Success
• P2P Committee Recognizes Role Models at NYMC

Prolongation Of The State Guarantee Scheme (Art. 2 Law 3723/2008), Margrethe Vestager, European Union: European Commission

Documents

State aid SA.46955 (2016/N) – Greece – Margrethe VESTAGER Member of the Commission

The Vibrio Cholerae Minor Pilin Tcpb Initiates Assembly And Retraction Of The Toxin-Coregulated Pilus, Dixon Ng, Tony Harn, Tuba Altindal, Subramania Kolappan, Jarrad Marles, Rajan Lala, Ingrid Spielman, Yang Gao, Caitlyn Hauke, Gabriela Kovacikova

Dartmouth Scholarship

Type IV pilus (T4P) systems are complex molecular machines that polymerize major pilin proteins into thin filaments displayed on bacterial surfaces. Pilus functions require rapid extension and depolymerization of the pilus, powered by the assembly and retraction ATPases, respectively. A set of low abundance minor pilins influences pilus dynamics by unknown mechanisms. The Vibrio cholerae toxin-coregulated pilus (TCP) is among the simplest of the T4P systems, having a single minor pilin TcpB and lacking a retraction ATPase. Here we show that TcpB, like its homolog CofB, initiates pilus assembly. TcpB co-localizes with the pili but at extremely low levels, equivalent …

The Effects Of Rarefaction And Thermal Non-Equilibrium On A Blunt Body And A Bicone In Hypersonic Flow And Their Shape Optimization For Reducing Both Drag And Heat Transfer, Samuel Gardner, Ramesh K. Agarwal

Mechanical Engineering and Materials Science Independent Study

Design of space vehicles pose many challenging problems due to their hypersonic speeds as they need to travel through different flow regimes due to changes in the density of the atmosphere with altitude. Some of the key characteristics associated with hypersonic flow are extremely high temperatures and heat transfer to the wall of the spacecraft. At these temperatures, the assumption of thermal equilibrium is no longer valid and the effect of rotational non-equilibrium must be included in the modeling of diatomic gas flow. This thesis employs the Navier-Stokes equations, which are modified to include a rotational non-equilibrium relaxation model to …

Learning Abaqus For Master's Thesis Project, Eric Yoon, Guy Genin

Mechanical Engineering and Materials Science Independent Study

I am writing to notify the results of the independent study that I have been performing over the semester of Fall 2016. The objective of this study was to lay a foundation of a Master’s thesis project at which the end goal would be to improve the repair rate of the human rotator cuff tear repairs. The experimental plots of the most recent models will be further attached.

Uncertainty Quantification (Uq) For Wall Modeled Large Eddy Simulation (Wmles) Model, Zuoxian Hou, Ramesh K. Agarwal

Mechanical Engineering and Materials Science Independent Study

In this paper non-intrusive uncertainty quantification (UQ) method is used to improve the accuracy of Smagorinsky Large eddy simulation (LES) model and a wall-modeled large eddy simulation (WMLES) model. Detailed UQ studies focusing on the closure coefficients of these two models are performed. A Polynomial Chaos (PC) surrogate model is used to evaluate the output sensitivities and uncertainties in the entire flow domain. The proposed UQ method allows for the investigation of specific flow features and phenomena within the domain. The results of the UQ analyses are then used to identify which closure coefficients in the models most influence the …

Computational Fluid Dynamics Simulation And Optimization Of 69-Degree-Delta Wing Model In Supersonic Flow, James Mitchell, Ramesh K. Agarwal

Mechanical Engineering and Materials Science Independent Study

The Computational Fluid Dynamics simulation and optimization of a 69-degree-deltawing model in a supersonic flow condition. The steady compressible Reynolds Averaged NavierStokes (RANS) equation using the inviscid Euler equations will be solved using the flow solver ANSYS Fluent. The CFD simulations will be compared to experimental and prior results before optimization begins. After simulation results compare well with AIAA sonic boom workshops provided data, a genetic algorithm will be created to optimize the deltawing to minimize the pressure disturbance [1]. The study of temperature effects on the pressure disturbance will also be considered using the sBOOM code provided by NASA …

Skull Shape Affects Susceptibility To Traumatic Brain Injury, Kashyap Arcot, Guy M. Genin

Mechanical Engineering and Materials Science Independent Study

Rapid deformation of brain matter caused by skull acceleration is one of the most significant causes of concussion and severe traumatic brain injury (TBI). Despite substantial research being conducted in this area of study, very little is understood regarding the mechanics of the brain when exposed to rapid acceleration. As a result, the biomechanics of TBI remain ambiguous. In the present study, we apply a new strain estimation algorithm that enables the tracking of strains on the periphery of an image onto data obtained from tagged gel phantom and human MR-images. We use this new method to quantify strain concentrations …

The Murray Ledger And Times, December 19, 2016, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Synthesis Of Biphasic Calcium Phosphate And Its Behaviour In Simulated Body Fluid, Bui X.V, Thang T.D

ASEAN Journal on Science and Technology for Development

The main goal of this study is to elaborate and evaluate the physicochemical properties of the synthetic biphasic calcium phosphate (BCP) powder: an associate compound of hydroxyapatite (HA): Ca10(PO4)6(OH)2 and beta-tricalcium phosphate (β-TCP): Ca3(PO4)2. The new compound BCP has two advantages: high bioactivity (HA) and fast biodegradation (β-TCP). The obtained powder of BCP was prepared by the precipitate method. XRD analysis confirmed the synthetic material contained both HA and β-TCP crystalline phases. SEM images showed that the small particles of HA attached to bigger particles of β-TCP in the structure morphology of BCP. The in vitro experiment was carried out …

Feasibility Study For Rural Health Clinic, Cynthia A. Noble

Doctor of Nursing Practice Scholarly Project

An Abstract of the Scholarly Project by

Cindy Noble

The purpose of this study was to determine the feasibility of a rural health clinic in the Adair, Oklahoma area. A mixed-mode survey was sent to 2,890 households within a certain zip code for the Adair community and surrounding area. A link for the survey was also included so the survey could be accessed on line. The total number of surveys returned was 88. The respondents of the survey did show a willingness to use healthcare clinic if one were available in Adair, Oklahoma. The surveying also showed that the majority …