Digital Commons Network^™

Beyond The Cloud: Why The Narrow Decision In American Broadcasting Cos. V. Aereo, Inc. May Have Broader Implications For Cloud-Computing, Robyn L. Rothman

Touro Law Review

No abstract provided.

2016-2017 Graduate Course Descriptions, Rochester Institute Of Technology

RIT Digital Archives

No abstract provided.

2016-2017 Undergraduate Course Descriptions, Rochester Institute Of Technology

RIT Digital Archives

No abstract provided.

Causes Of Open Fractures: Orthopaedic Injuries Related To Home-Made Agricultural Vehicles In The Eastern Black Sea Region Of Turkey, Ferhat Say, Hüseyi̇n Si̇na Coşkun, Murat Erdoğan, Ahmet Murat Bülbül, Deni̇z Gürler

Turkish Journal of Medical Sciences

Background/aim: Small vehicles known locally as pat-pats, which are used in agricultural work, are forbidden in traffic. The inherent instability of the vehicle may result in accidents, both on farmland and in traffic. The aim of this study was to evaluate orthopaedic injuries related to pat-pats. Materials and methods: Patients hospitalised for pat-pat accidents in two central hospitals in Samsun between December 2006 and October 2013 were scanned using ICD codes. A total of 46 patients with orthopaedic injuries (43 male, 3 female) with a mean age of 36 ± 13.3 years were evaluated. Results: The most injured age group …

The User Principle: Rashomon Effect Or Much Ado About Nothing?, Kelvin F. K. Low

Research Collection Yong Pung How School Of Law

No abstract provided.

Gallium-Containing Mesoporous Bioactive Glass With Potent Hemostatic Activity And Antibacterial Efficacy, Sara Pourshahrestani, Ehsan Zeimaran, Nahrizul Adib Kadri, Nicola Gargiulo, Shani Samuel, Sangeetha Vasudevaraj Naveen, Tunku Kamarul, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Haemorrhage remains the leading cause of potentially survivable death in both military and civilian populations. Although a large variety of hemostatic agents have been developed, many of them have an inadequate capacity to induce hemostasis and are not effective in killing bacteria. In recent years, mesoporous bioactive glasses (MBGs) were found to be effective in inducing hemostasis. However, the materials may not be considered as ideal hemostats since they do not offer antimicrobial activity. The gallium ion (Ga⁺³) not only exhibits antibacterial properties but also accelerates the blood coagulation cascade. The aim of this study was to develop …

Review Of Barry Allen, Vanishing Into Things: Knowledge In Chinese Tradition, Alan Kam Leung Chan

Research Collection College of Integrative Studies

Vanishing into Things: Knowledge in Chinese Tradition. By Barry Allen. Cambridge, MA and London, England: Harvard University Press, 2015. Pp. viii + 289.This book is about conceptions of knowledge in Chinese philosophy, but it also does more than that. It raises new possibilities for comparative philosophy and points to ways in which philosophy as an academic discipline could be reinvigorated to help address the global challenges of the twenty-first century.

3for2: Realizing Spatial, Material, And Energy Savings Through Integrated Design, Arno Schlueter, Adam Rysanek, Clayton Miller, Jovan Pantelic, Forrest Meggers, Matthias Mast, Marcel Bruelisauer, Chen Kian Wee

Research Collection College of Integrative Studies

As the world adapts to dual trends of climate change and urbanization, tall office buildings in hot and humid climate zones near the equator are among the prime candidates for a significant change in design approach. Though many individualized improvements to operating systems, envelopes and material selections have been introduced in recent years, it is generally agreed a holistic approach is needed to truly capitalize on the smaller-scale innovations. With a focus on reducing the necessary size of the services plenum, in this paper, an alternative paradigm for the optimization of space, material, and energy use in buildings is presented: …

Bioactivity/Cytotoxicity Of Micro-/Nano-Materials And Novel Development Of Fiber-Optic Probes For Single Cell Monitoring, Qingbo Yang

Doctoral Dissertations

"Manufactured nano-/micro-materials (MNMs) have been widely used and their interactions with niche biological environment are highly concerned for both of their biohazardous and bioactive effects, whereas no available comprehensive evaluations or regulations have been provided yet. This dissertation thus focuses on three major aspects: 1) fundamental toxicity understandings of a typical MNMs (zinc oxide nanoparticles), 2) bioactivity evaluations of representative bioactive MNMs, and 3) development of novel micro-probes for high spatial resolution monitoring. Firstly, the NP's concentration, irradiation, hydrodynamic size, and the localized pH, ionic strength, NP zeta-potential as well as dissolved oxygen levels were found correlated with the production …

No U-Turn Needed On The Elected Presidency, Tan K. B. Eugene

Research Collection Yong Pung How School Of Law

SMU Associate Professor of Law Eugene Tan cited the commentary "Let's talk about policy failures and the elected presidency" by Professor Kishore Mahbubani, where the latter argued that Singapore’s policy of an elected presidency should be revisited, and perhaps "the time has come to do a U-turn", stop having direct elections and go back to the previous practice of having Parliament elect the president. While Associate Prof Tan noted that Prof Mahbubani's concern is legitimate, he emphasised that the way forward is not a U-turn, but rather, a collective effort to determine how we can reduce the likelihood of electing …

Lazer: Distributed Memory-Efficient Assembly Of Large-Scale Genomes, Sayan Goswami, Arghya Kusum Das, Richard Platania, Kisung Lee, Seung Jong Park

Computer Science Faculty Research & Creative Works

Genome sequencing technology has witnessed tremendous progress in terms of throughput as well as cost per base pair, resulting in an explosion in the size of data. Consequently, typical sequence assembly tools demand a lot of processing power and memory and are unable to assemble big datasets unless run on hundreds of nodes. In this paper, we present a distributed assembler that achieves both scalability and memory efficiency by using partitioned de Bruijn graphs. By enhancing the memory-to-disk swapping and reducing the network communication in the cluster, we can assemble large sequences such as human genomes (452 GB) on just …

Transient Cfd Simulations Of Pumping And Mixing Using Electromagnetic, Fangping Yuan

Doctoral Dissertations

"In this dissertation, two dimensional and three dimensional, transient CFD simulations are conducted to investigate the active pumping and mixing in microfluidics driven by Electromagnetic/Lorentz force. Shallow disk/ring cylindrical microfluidic cell and shallow cuboid microfluidic cell with electrodes deposited on the bottom surface are modelled for mixing and pumping purposes respectively. By applying voltage across specific pair of electrodes, an ionic current is established in the weak conductive liquid present in the cell. The current interacts with an externally applied magnetic field generating a Lorentz force that causes fluid motion in the cell. Velocity vectors, electric potential distributions and ionic …

Src Family Kinases Mediate Individual Cell Responses To Receptor Tyrosine Kinase Signaling In Neuroblastoma Cells, Juan Enrique Palacios Moreno

Graduate Student Theses, Dissertations, & Professional Papers

Receptor Tyrosine Kinases (RTKs) are involved in proliferation, differentiation, cellular metabolism, and homeostasis. More than half of the RTKs in the human genome are expressed in neuroblastoma cell lines. RKTs activate downstream signaling pathways including the canonical pathways of ERK, AKT, PLCγ, and SRC Family Kinases (SFKs). Phosphoproteomic data showed high expression and phosphorylation levels of SFK scaffold PAG1, and SFKs FYN and LYN in neuroblastoma cell lines and endosomes. We hypothesized that FYN and LYN distinguish between proliferation- and differentiation-inducing signals from different RTKs in neuroblastoma cells.

To test this hypothesis, we measured changes in FYN and LYN’s intracellular …

Applications Of Simulation And Optimization Techniques In Optimizing Room And Pillar Mining Systems, Angelina Konadu Anani

Doctoral Dissertations

"The goal of this research was to apply simulation and optimization techniques in solving mine design and production sequencing problems in room and pillar mines (R&P). The specific objectives were to: (1) apply Discrete Event Simulation (DES) to determine the optimal width of coal R&P panels under specific mining conditions; (2) investigate if the shuttle car fleet size used to mine a particular panel width is optimal in different segments of the panel; (3) test the hypothesis that binary integer linear programming (BILP) can be used to account for mining risk in R&P long range mine production sequencing; and (4) …

Evaluating Of Scale-Up Methodologies Of Gas-Solid Spouted Beds For Coating Triso Nuclear Fuel Particles Using Advanced Measurement Techniques, Neven Y. Ali

Doctoral Dissertations

"The work focuses on implementing for the first time advanced non-invasive measurement techniques to evaluate the scale-up methodology of gas-solid spouted beds for hydrodynamics similarity that has been reported in the literature based on matching dimensionless groups and the new mechanistic scale up methodology that has been developed in our laboratory based on matching the radial profile of gas holdup since the gas dynamics dictate the hydrodynamics of the gas-solid spouted beds. These techniques are gamma-ray computed tomography (CT) to measure the cross-sectional distribution of the phases' holdups and their radial profiles along the bed height and radioactive particle tracking …

Blended Learning In Chemistry Laboratory Courses: Enhancing Learning Outcomes And Aligning Student Needs With Available Resources, Shayna Brianne Burchett

Doctoral Dissertations

"Freshman science courses are intended to prepare students for the rigor and expectations of subsequent college science. While secondary education aims to prepare students for the college curriculum, many incoming freshman lack the sense of responsibility for their own learning that is essential for success in a college-level course. The freshman general-chemistry laboratory course at Missouri University of Science and Technology (Missouri S&T) was identified as a bottleneck course with a demand beyond accommodation capacity. To address the bottleneck and develop a sense of learner responsibility, a decision was made to investigate laboratory course delivery strategies. As a result of …

Subterranean Photobioreactors For Commercial-Industrial Scale Algal Culture, Daniel James Vidt

Doctoral Dissertations

"There are many potential benefits to the mining industry accruing from the application of algal biotechnology. The main benefits are in the production of biodiesel and in the remediation of mining brownfields. The research in this study was centered in the original idea that these brownfields represent a tremendous opportunity for use as a hybrid model for redevelopment into sustainable "mines" of biomass. The ability of these underground spaces serving as bioreactors to control all aspects of the growing environment, from lighting, to temperature, to biosecurity, are key advantages that have been identified in the literature. The many benefits inherent …

Study Of Heat Transfer Phenomenon During Natural Convection, Muhammad Yousaf

Doctoral Dissertations

"The purpose of the present study was to numerically investigate the effects of the roughness elements on the heat transfer during natural convection. A computational algorithm was developed based on the Lattice Boltzmann method to conduct numerical study in two-dimensional rectangular cavities and Rayleigh-Bénard cell. A single relaxation time Bhatnagar-Gross-Krook model of Lattice Boltzmann method was used to solve the coupled momentum and energy equations in two-dimensional lattices. Computational model was validated against previous benchmark solutions, and a good agreement was found to exist. A Newtonian fluid of Prandtl (Pr) number 1.0 was considered for this numerical study. The range …

Detecting, Segmenting And Tracking Bio-Medical Objects, Mingzhong Li

Doctoral Dissertations

"Studying the behavior patterns of biomedical objects helps scientists understand the underlying mechanisms. With computer vision techniques, automated monitoring can be implemented for efficient and effective analysis in biomedical studies. Promising applications have been carried out in various research topics, including insect group monitoring, malignant cell detection and segmentation, human organ segmentation and nano-particle tracking.

In general, applications of computer vision techniques in monitoring biomedical objects include the following stages: detection, segmentation and tracking. Challenges in each stage will potentially lead to unsatisfactory results of automated monitoring. These challenges include different foreground-background contrast, fast motion blur, clutter, object overlap and …

A Control Theoretic Approach For Security Of Cyber-Physical Systems, Haifeng Niu

Doctoral Dissertations

"In this dissertation, several novel defense methodologies for cyber-physical systems have been proposed. First, a special type of cyber-physical system, the RFID system, is considered for which a lightweight mutual authentication and ownership management protocol is proposed in order to protect the data confidentiality and integrity. Then considering the fact that the protection of the data confidentiality and integrity is insufficient to guarantee the security in cyber-physical systems, we turn to the development of a general framework for developing security schemes for cyber-physical systems wherein the cyber system states affect the physical system and vice versa. After that, we apply …

Efficient And Quantitative Emc Predictions (Emission And Immunity) For Ecu Modules, Guangyao Shen

Doctoral Dissertations

"This dissertation consists of three papers. In the first paper, a methodology of building an IC model capable of predicting failures for given disturbances at the clock input based on limited or no knowledge about IC internals was developed.

In the second paper, the maximized radiated emissions of the heat-sink/IC structure are predicted up to 40 GHz by creating an equivalent source using the measured electrical field in the gap between the heat-sink and ICs. The electric field is detected by an E-field probe made of an open coaxial cable coated with absorbing material. A numerical model is built in …

Development Of Implants Composed Of Bioactive Materials For Bone Repair, Wei Xiao

Doctoral Dissertations

"The purpose of this Ph.D. research was to address the clinical need for synthetic bioactive materials to heal defects in non-loaded and loaded bone. Hollow hydroxyapatite (HA) microspheres created in a previous study were evaluated as a carrier for controlled release of bone morphogenetic protein-2 (BMP2) in bone regeneration. New bone formation in rat calvarial defects implanted with BMP2-loaded microspheres (43%) was significantly higher than microspheres without BMP2 (17%) at 6 weeks postimplantation. Then hollow HA microspheres with a carbonate-substituted composition were prepared to improve their resorption rate. Hollow HA microspheres with ~12 wt. % of carbonate showed significantly higher …

The Effect Of Scoliotic Deformity On Spine Kinematics In Adolescents., Sarah Galvis, Douglas Burton, Brandon Barnds, John Anderson, Richard M. Schwend, Nigel Price, Sara Wilson, Elizabeth Friis

Manuscripts, Articles, Book Chapters and Other Papers

Background: While adolescent idiopathic scoliosis (AIS) produces well characterized deformation in spinal form, the effect on spinal function, namely mobility, is not well known. Better understanding of scoliotic spinal mobility could yield better treatment targets and diagnoses. The purpose of this study was to characterize the spinal mobility differences due to AIS. It was hypothesized that the AIS group would exhibit reduced mobility compared to the typical adolescent (TA) group.

Methods: Eleven adolescents with right thoracic AIS, apices T6-T10, and eleven age- and gender-matched TAs moved to their maximum bent position in sagittal and coronal plane bending tasks. A Trakstar …

Book Review: Student Writing In The Quantitative Disciplines: A Guide For College Faculty, Mark Causapin

All Works

No abstract provided.

Change-Point Detection In The Marginal Distribution Of A Linear Process, Farid El Ktaibi, B. Gail Ivanoff

All Works

© 2016, Institute of Mathematical Statistics. All rights reserved. The subject of this paper is the detection of a change in the marginal distribution of a stationary linear process. By considering the marginal distribution, the change-point model can simultaneously incorporate any change in the coefficients and/or the innovations of the linear process. Furthermore, the change point can be random and data dependent. The key is an analysis of the asymptotic behaviour of the sequential empirical process, both with and without a change point. Our results hold under very mild conditions on the existence of any moment of the innovations and …

A Conceptual Model To Determine Vulnerability Of Wildlife Populations To Offshore Wind Energy Development, M. Wing Goodale, Iain J. Stenhouse

Human–Wildlife Interactions

As offshore wind energy development is planned in the United States, there is an increasing need for pre- and post-construction monitoring plans to be focused on species determined to be most vulnerable to hazards of a specific project. We propose a conceptual model that incorporates biological and sociological parameters. Specifically, we suggest that demographic, ethological/biological, and population sensitivity be considered with legal protection, economic importance, and/or stakeholder interest. We recommend that vulnerability determinations include qualitative and quantitative methods.

Declining Populations Of Greater Sage-Grouse: Where And Why, Michael R. Conover, Anthony J. Roberts

Human–Wildlife Interactions

Scientists have been predicting the extinction of greater sage-grouse (Centrocercus urophasianus) since 1916, and sage-grouse populations have declined relentlessly during the last century despite attempts to reverse the decline. In this review paper, we examined the scientific literature to evaluate hypotheses about why sage-grouse populations have declined. There is little support for the hypotheses that the decline is due to overhunting, parasites, food shortages, or collisions with power lines or fences. West Nile Virus (WNV) reduced sagegrouse up to 25% when the virus first reached the West during 2002, but sage-grouse have developed resistance to the virus since …

Post-Disaster Supply Chain Interdependent Critical Infrastructure System Restoration: A Review Of Data Necessary And Available For Modeling, Varun Ramachandran, Suzanna Long, Tom Shoberg, Steven Corns, Hector J. Carlo

Engineering Management and Systems Engineering Faculty Research & Creative Works

The majority of restoration strategies in the wake of large-scale disasters have focused on short-term emergency response solutions. Few consider medium- to long-term restoration strategies to reconnect urban areas to national supply chain interdependent critical infrastructure systems (SCICI). These SCICI promote the effective flow of goods, services, and information vital to the economic vitality of an urban environment. To re-establish the connectivity that has been broken during a disaster between the different SCICI, relationships between these systems must be identified, formulated, and added to a common framework to form a system-level restoration plan. To accomplish this goal, a considerable collection …

The Challenge Of Analyzing The Results Of Next-Generation Sequencing In Children., Isabelle Thiffault, John Lantos

Manuscripts, Articles, Book Chapters and Other Papers

In recent years, next-generation sequencing technologies have revolutionized approaches to genetic studies. Whole-exome or whole-genome sequencing allows diagnoses in many patients who have complex phenotypes and unusual clinical presentations. As genomic and exomic testing expands in both the research and clinical settings, pediatricians will need to understand the technology of next-generation sequencing and the complexity of interpreting genomic variants relevant to patient phenotypic features. This article briefly explains the technology by which genomes are sequenced and discusses some of the complexity related to interpreting genomic variants. We conclude with some thoughts on the clinical applications of such testing.

In Silico Genome-Wide Identification And Analysis Of Microsatellite Repeats In The Largest Rna Virus Family (Closteroviridae), Biju George, Binu George, Mayur Awasthi, Ram Nageena Singh

Turkish Journal of Biology

Microsatellites are known to exhibit ubiquitous presence across all kingdoms of life, including viruses. Members of the family Closteroviridae are the largest RNA viruses and severely affect different agricultural crops worldwide, including1397645907citrus, grapevine, and vegetables. Here we identified and systematically analyzed the nature and distribution of both simple and complex microsatellites present in the complete genome of 36 species belonging to Closteroviridae. Our results showed, in all analyzed genomes, that neither genome size nor GC content had any influence on number, relative abundance, or relative density of microsatellites. For each genome, dinucleotide repeats were found to be highly predominant and …