Digital Commons Network^™

Cyclic Di-Gmp-Regulated Periplasmic Proteolysis Of A Pseudomonas Aeruginosa Type Vb Secretion System Substrate, Richard B. Cooley, T. Jarrod Smith, Wilfred Leung, Valerie Tierney, Bradley Borlee, George A. O'Toole, Holger Sondermann

Dartmouth Scholarship

We previously identified a second-messenger-regulated signaling system in the environmental bacterium Pseudomonas fluorescens which controls biofilm formation in response to levels of environmental inorganic phosphate. This system contains the transmembrane cyclic di-GMP (c-di-GMP) receptor LapD and the periplasmic protease LapG. LapD regulates LapG and controls the ability of this protease to process a large cell surface adhesin protein, LapA. While LapDG orthologs can be identified in diverse

The Influence Of Floodplain Restoration On Flow And Sediment Dynamics In An Urban River, Sangaralingam Ahilan, Mingfu Guan, Andrew Sleigh, Nigel G. Wright, Heejun Chang

Geography Faculty Publications and Presentations

A study of floodplain sedimentation on a recently restored floodplain is presented. This study uses a two-dimensional hydro-morphodynamic model for predicting flow and suspended-sediment dynamics in the downstream of Johnson Creek, the East Lents reach, where the bank of the river has been reconfigured to reconnect to a restored floodplain on a 0.26 km² (26-ha) site. The simulation scenarios include 10-, 50-, 100- and 500-year event-based deposition modelling of flood events and long-term modelling using the 64 historical flood events between 1941 and 2014. Simulation results showed that the restored floodplain significantly attenuates the upstream flood peak by up …

Optimizing Methods For Extraction Of Organic Compounds From Molluscan Shells, Kaydee Jo West

USF Tampa Graduate Theses and Dissertations

Mollusk shells contain proteins within and between the crystals of calcium carbonate. These organic molecules play an important role in biomineralization and shell function, and their stable isotope ratios of carbon and nitrogen are also thought to record important ecological information about the animal's diet and nutrient sources. These proteins can be preserved for millions of years, offering potential insight into pre-anthropogenic ecological conditions. However, shell organics in older shells are typically recovered in reduced abundances due to leaching and remaining organics are often converted from insoluble proteins to soluble, free amino acids, making them difficult to detect and recover. …

Status Gizi Dan Kualitas Hidup Pada Lansia Pengguna Gigitiruan Penuh Di Kota Makassar, Bahruddin Thalib, Khumairah Nur Ramadhani, Asmawati Asmawati

Media Kesehatan Masyarakat Indonesia

Prevalensi kehilangan seluruh gigi pada lansia di Indonesia cukup tinggi, khususnya di Kota Makassar. Kehilangan gigi yang tidak disertai dengan penggantian gigi palsu akan menggangu asupan nutrisi yang akan berdampak pada kesehatan secara umum yang pada akhirnya akan mempengaruhi kualitas hidup seseorang. Penelitian ini bertujuan menganalisis hubungan penggunaan gigitiruan penuh dengan status gizi dan kualitas hidup pada lansia di Kota Makassar. Penelitian ini merupakan penelitian observasional analitik dengan rancangan cross sectional. Penentuan lokasi penelitian menggunakan stratified random sampling, yaitu Kecamatan Ujung Tanah, Tamalate, dan Ujung Pandang. Sebanyak 283 lansia usia 60 tahun keatas diperoleh dengan purposive sampling bersedia mengikuti penelitian …

Autocidal Ovitrap Atraktan Rendaman Jerami Sebagai Alternatif Pengendalian Vektor Dbd Di Kab. Gunungkidul, Indra Dwinata, Tri Baskoro, Citra Indriani

Media Kesehatan Masyarakat Indonesia

Kabupaten Gunungkidul adalah daerah endemis DBD di Provinsi Yogyakarta. Salah satu alternatif dalam pengendalian vektor DBD adalah dengan memasang autocidal ovitrap dengan menambahkan zat atraktan berupa air rendaman jerami. Penelitian ini bertujuan mengetahui pengaruh pemasangan autocidal ovitrap dengan atraktan air rendaman jerami terhadap jumlah nyamuk Aedes yang terperangkap dan index kepadatan larva. Design penelitian ini adalah quasi eksperimental dengan rancangan crossover design. Dilakukan di tiga daerah endemis DBD. Jumlah rumah 55-65 setiap daerah. Intervensi, yaitu penggunaan autocidal ovitrap atraktan air rendaman jerami dan autocidal ovitrap air biasa dan satu daerah kontrol tanpa penggunaan autocidal ovitrap. Intervensi berlangsung selama 10 minggu. …

Faktor Risiko Stunting Usia 6-23 Bulan Di Kecamatan Bontoramba Kabupaten Jeneponto, Nasrul Nasrul, Fahmi Hafid, Abdul Razak Thaha, Suriah Suriah

Media Kesehatan Masyarakat Indonesia

Stunting adalah retardasi pertumbuhan linier kurang dari -2 SD standar WHO pertumbuhan anak panjang badan menurut usia. Penelitian ini bertujuan untuk menganalisis faktor risiko stunting anak usia 6-23 bulan di Kecamatan Bontoramba Kabupaten Jeneponto. Penelitian ini merupakan penelitian analitik dengan rancangan cross sectional study. Populasi penelitian ini sebanyak 410 set e-files data survei gizi & kesehatan ibu dan anak Kecamatan Bontoramba, Kabupaten Jeneponto 2014 dengan sampel sebanyak 350 set data yang diambil dengan teknik exhaustive sampling. Data dianalisis dengan uji chi square dan regresi logistic. Hasil penelitian menunjukkan bahwa faktor risiko stunting dalam penelitian ini adalah (OR; p value), berat …

Practice Matters: Red Flags In Adults With Mental Illnesses, Lynette S. Smith Phd, Aprn, Pmhnp, Fnp, Tonya Bragg-Underwood Dnp, Fnp-Bc, Cne, W. Spencer Cole Msn, Rn

International Journal of Faith Community Nursing

Faith Community Nurses have common beliefs, principles, ethics, and a level of trust with their population making them well-positioned to positively impact parishioners. FCNs provide support for people’s spiritual needs and nursing care. This makes FCNs a vital and approachable resource for parishioners when seeking advisement and assistance regarding their mental healthcare. In this article, we define red flags as suicidal idealization, mania, and psychosis, which if not promptly assessed and referred for treatment may result in serious harm or death. These red flags are predominately found in people with schizophrenia, depression, bipolar disorder, and post-traumatic stress disorder. People with …

The Tree Of Life Model Of Faith-Based Living: A Practice Model For Faith Community Nursing, Marcus M. Gaut

International Journal of Faith Community Nursing

The advancement of nursing practice is supported by a plethora of theories, conceptual models, and theoretical frameworks. Additionally, the complexity of nursing and the profession’s ability to respond to diverse manifestations of patient or client response to illness manifests in a number of specialty areas of practice. Faith Community Nursing is a specialty area of nursing practice that appears to lack a specific conceptual model upon which to support the faith-based practice of Faith Community Nurses. The Tree of Life Model of Faith-Based Living, an adaptation of the Activities of Living Model, supports the faith-based practice of Faith Community Nurses …

Song Types, Repertoires And Patterns Of Song Sharing Among Canyon Wrens, Catherpes Mexicanus, Anne Rose

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

No abstract provided.

Divergence Of Sulfur-Flower Buckwheat Using Dna Analyses, Taylor Brevik, Mitchell Mcglaughlin

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

No abstract provided.

Cloning Of Immunoglobulin Cdnas From The Jamaican Fruit Bat, Benjamin Lee

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

No abstract provided.

Natural Compounds As Sources Of New Drugs: Venoms And Cancer, Brianne Broughton

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

No abstract provided.

A Study Of Obligated And Unobligated Time Use Among Unc Students, Schlarbaum Konrad, Kaneesha Davis

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

The purpose of this research was to assess obligated and unobligated time use among University of Northern Colorado (UNC) students within an average twenty-four hour day of the fifteen week semester. A convenience sample of 195 UNC undergraduate students completed a 19-item questionnaire composed of closed ended questions involving time allotments to obligated and unobligated activities. Results indicated that UNC students spend approximately the same amount of time in obligated and unobligated activity. Means testing across the seven time categories revealed no significant differences between male and female students. However, mean testing between upper classmen and lower classmen indicated that …

Effects Of Multilevel Selection On The Evolution Of Homo Neandertalensis, Tracey Renee Lancaster

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

In this article, a model is used based on a paper by E. O. Wilson et al. (2007) to examine how multilevel selection has affected the evolution of Neandertals. Multilevel selection theory states natural selection occurs in multiple levels of the biological hierarchy. This model has never been applied to a hominid species to date. By synthesizing this research by Wilson et al. and genetic studies by Green et al. (2010) revealing that Neandertals and humans interbred in the Middle East 80,000 years ago, it is shown that multilevel selection may have affected Neandertal evolution. Further, it is argued that …

The Snakehead War: Administrative Rule-Making And Legislative Strategies To Minimize Destruction By The Northern Snakehead, Joshua Rice

William & Mary Environmental Law and Policy Review

No abstract provided.

Aransas Project V. Shaw: The Fifth Circuit’S Incorrect And Attenuated Proximate Cause Analysis On What Killed The Whooping Crane, Brian Reagan

William & Mary Environmental Law and Policy Review

No abstract provided.

Saving The Orange: How To Fight Citrus Greening Disease (And It’S Not Through Genetic Engineering), Evan Feely

William & Mary Environmental Law and Policy Review

No abstract provided.

Productivity And Diversity In Research And Agriculture: Improving The Ipr Landscape For Food Security, A. Max Jarvie

William & Mary Environmental Law and Policy Review

While food security has long been a national or regional burden, the advent of international instruments governing intellectual property rights over conventionally bred plant varieties and genetically modified plants has made the management of food security a global concern. Current intellectual property regimes do not provide clear support for innovations in crop productivity or biodiversity, both of which are implicated in the long term stability of food supply. This Paper examines the intellectual property regimes governing agricultural food stocks with respect to the level of support they provide for three key research programs in the development of crop seeds and …

Coercing Collaboration: The Chesapeake Bay Experience, Jamison E. Colburn

William & Mary Environmental Law and Policy Review

This Article uses a detailed case study of the Chesapeake to describe an emergent model of intergovernmental administration tailored to address our largest-scale environmental problems. The Obama EPA’s “total maximum daily load” (“TMDL”) in the Chesapeake has yet to be replicated. But it should be. The TMDL and its supporting norms were unique as an operational plan, achieving a level of transparency, accountability, means/ends rationality, and continuous improvement that were unprecedented at its scale. And whether this model can be replicated elsewhere turns out to be as much a question of law as of politics.

Dissociation Dynamics Of Xpc-Rad23b From Damaged Dna Is A Determining Factor Of Ner Efficiency, Benjamin Hilton, Sathyaraj Gopal, Lifang Xu, Sharmistha Mazumder, Phillip R. Musich, Bongsup P. Cho, Yue Zou

Biomedical and Pharmaceutical Sciences Faculty Publications

XPC-RAD23B (XPC) plays a critical role in human nucleotide excision repair (hNER) as this complex recognizes DNA adducts to initiate NER. To determine the mutagenic potential of structurally different bulky DNA damages, various studies have been conducted to define the correlation of XPC-DNA damage equilibrium binding affinity with NER efficiency. However, little is known about the effects of XPC-DNA damage recognition kinetics on hNER. Although association of XPC is important, our current work shows that the XPC-DNA dissociation rate also plays a pivotal role in achieving NER efficiency.We characterized for the first time the binding of XPC to mono- versus …

Functional/Activity Network (Fan) Analysis Of Gene-Phenotype Connectivity Liaised By Grape Polyphenol Resveratrol, Tze-Chen Hsieh, Sheng-Tang Wu, Dylan J. Bennett, Barbara B. Doonan, Erxi Wu, Joseph M. Wu

NYMC Faculty Publications

Resveratrol is a polyphenol that has witnessed an unprecedented yearly growth in PubMed citations since the late 1990s. Based on the diversity of cellular processes and diseases resveratrol reportedly affects and benefits, it is likely that the interest in resveratrol will continue, although uncertainty regarding its mechanism in different biological systems remains.We hypothesize that insights on disease-modulatory activities of resveratrol might be gleaned by systematically dissecting the publicly available published data on chemicals and drugs. In this study, we tested our hypothesis by querying DTome (Drug-Target Interactome), a web-based tool containing data compiled from open-source databases including DrugBank, PharmGSK, and …

Mixed Waste Landfill Annual Long-Term Monitoring & Maintenance Report, April 2015-March 2016 For Sandia National Laboratories/New Mexico, Epa Id Number Nm5890110518 June 2016, Sandia National Laboratories/Nm

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE) and Sandia Corporation are submitting the Mixed Waste Landfill (MWL) Annual Long-Term Monitoring and Maintenance Report for the April 2015 through March 2016 reporting period. This report satisfies the requirements of Section 4.8.1 of the MWL Long-Term Monitoring and Maintenance Plan (LTMMP). The annual reporting period runs from April 1 to March 31.

The MWL is a 2.6-acre Solid Waste Management Unit (SWMU 76) which has undergone corrective action. The MWL is located in the north central portion of Sandia National Laboratories (SNL)/New Mexico (NM) Technical Area III. During the operational period …

June 21, 2016 Minutes, Swosu Faculty Senate

Faculty Senate Minutes

SWOSU Faculty Senate June 21, 2016 Approved Minutes

Independent - Jun. 21, 2016, Brett Starkopf

The Independent (1988-present)

No abstract provided.

Contest Or Congruence: The Effects Of Work/School Conflict And Facilitation On Working College Students, Madeline Mareen Miscenich

Theses and Dissertations

The purpose of this study was to find out more about working students perspectives on work/school conflict and facilitation. The subjects that participated in the study included students workers of Rowan University employed through the Federal Work Study (FWS) Program in the area of Gloucester County, New Jersey. Data from the subjects were gathered using a quantitative survey design, with items presented in a Likert scale format. The data were analyzed using SPSS Software, and frequency of response, measures of central tendency, and Pearson correlations were examined in order to determine student attitudes regarding work/school conflict and facilitation. Subjects were …

Characterization Of The Microbiome Of Nipple Aspirate Fluid Of Breast Cancer Survivors., Alfred A Chan, Mina Bashir, Magali N Rivas, Karen Duvall, Peter A Sieling, Thomas R Pieber, Parag A Vaishampayan, Susan M Love, Delphine J Lee

Articles, Abstracts, and Reports

The microbiome impacts human health and disease. Until recently, human breast tissue and milk were presumed to be sterile. Here, we investigated the presence of microbes in the nipple aspirate fluid (NAF) and their potential association with breast cancer. We compared the NAF microbiome between women with a history of breast cancer (BC) and healthy control women (HC) using 16S rRNA gene amplicon sequencing. The NAF microbiome from BC and HC showed significant differences in community composition. Two Operational Taxonomic Units (OTUs) showed differences in relative abundances between NAF collected from BC and HC. In NAF collected from BC, there …

Staphylococcus Aureus Coordinates Leukocidin Expression And Pathogenesis By Sensing Metabolic Fluxes Via Rpirc, Divya Balasubramanian, Elizabeth A Ohneck, Jessica Chapman, Andy Weiss, Min Kyung Kim, Tamara Reyes-Robles, Judy Zhong, Lindsey N. Shaw, Desmond S. Lun, Beatrix Ueberheide, Bo Shopsin, Victor J Torres

Molecular Biosciences Faculty Publications

Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors to injure immune cells and promote infection of its host. Of these proteins, the bicomponent family of pore-forming leukocidins play critical roles in S. aureus pathogenesis. The regulatory mechanisms governing the expression of these toxins are incompletely defined. In this work, we performed a screen to identify transcriptional regulators involved in leukocidin expression in S. aureus strain USA300. We discovered that a metabolic sensor-regulator, RpiRc, is a potent and selective repressor of two leukocidins, LukED and LukSF-PV. Whole-genome transcriptomics, S. aureus exoprotein proteomics, and metabolomic analyses revealed that …

An Antarctic Sponge Offers New Hope Against Deadly Mrsa Infection, Staff

Browse All News

No abstract provided.

Compositions And Methods For Treating Ischemia, Gregory J. Bix

Sanders-Brown Center on Aging Faculty Patents

The presently-disclosed subject matter provides methods for preventing ischemia in a cell, treating ischemia in a subject, and preventing an infarction in a subject that utilize α5β1 integrin inhibitor. In some instances, α5β1 integrin inhibitor is administered to a subject prior to, during, or after the onset of ischemia to treat the ischemia and/or prevent infarction. In some instances the present methods prevent the occurrence of an infarction. In some instances the present methods restores perfusion to organs and tissues.

Direct Reprogramming To Multipotent Trophoblast Stem Cells, And Is Pluripotency Needed For Regenerative Medicine Either?, Yu Yang, Graham C. Parker, Elizabeth E. Puscheck, Daniel A. Rappolee

Department of Obstetrics and Gynecology Research Publications

No abstract provided.