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Small-Angle X-Ray Scattering Studies Of The Oligomeric State And Quaternary Structure Of The Trifunctional Proline Utilization A (Puta) Flavoprotein From Escherichia Coli, Ranjan K. Singh, John D. Larson, Weidong Zhu, Robert P. Rambo, Greg L. Hura, Donald F. Becker, John J. Tanner

Department of Biochemistry: Faculty Publications

Background: Trifunctional proline utilization A (PutA) proteins are multifunctional flavoproteins that catalyze two reactions and repress transcription of the put regulon.

Results: PutA from Escherichia coli is a V-shaped dimer, with the DNA-binding domain mediating dimerization.

Conclusion: Oligomeric state and quaternary structures are not conserved by PutAs.

Significance: The first three-dimensional structural information for any trifunctional PutA is reported.

Changing Skeletal Stress Following Social And Political Disruption At Karystos, Greece, Jeremy Wharry

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

No abstract provided.

Examining Students’ Expectations For Laboratory Learning In A Majors’ Introductory Biology Course, Matthew Crewse

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

No abstract provided.

Result Inequality In Family Law, Margaret F. Brinig

Akron Law Review

To the extent that family law is governed by statute, all families are treated as though they are the same. This is of course consistent with the equal protection guarantees of the U.S. Constitution as well as those of the states. However, in our pluralistic society, all families are not alike. At birth, some children are born to wealthy, married parents who will always put the children’s interests first and will never engage in domestic violence. Many laws benefit these children, while, according to some academics, they either further disadvantage other children or at best ignore their needs.

This Article …

Introduction To Socio-Economics: An Ethical Foundation For Law-Related Economic Analysis, Robert Ashford

Akron Law Review

This introductory Article to the Symposium Issue on Law and Socio-Economics (1) briefly explains the origin of the term “socio-economics,” (2) recounts the history of its formal introduction into legal education in 1997, (3) sets forth its underlying principles as a specific methodological approach to law-related economic analysis, (4) describes in greater detail some of its most important features, (5) compares the socio-economic approach to the narrower, neoclassical economic approach that dominates scholarship in “law and economics,” (6) explains the special connection between socio-economic principles and the ethical responsibilities of lawyers related to competence, candor, and the lawyer’s role as …

Reconstructing Activity Patterns At Epidamnus, Albania: Impacts Of Greek And Roman Colonizations, Jennifer Wright

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Colonization is often associated with exploitation of local laborers. However, the degree to which physical activity in local populations changes following colonization depends upon the policies of the colonizers, and the technologies that are locally available. This research tests the null hypothesis that levels of physical activity, as evidenced by osteoarthritis in human skeletons, remained constant at Epidamnus, Albania during Greek and Roman colonial occupation (620 BC-AD 378). To test this hypothesis, 80 skeletons from Epidamnus were examined for evidence of osteoarthritis, and scored according to international standardized protocols. Of these 80 individuals, 27 were adults that showed sufficient preservation …

Social Inference And Reading Inference Generation In Typically Developing College Students, Pamela Wagoner

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Although the foundational cognitive and linguistic skills of generating inferences in both reading and social contexts are similar, relationships between these two modalities, and with empathy, are unclear and have not been thoroughly studied. These relationships were explored by testing 30 typically developing college students’ ability to generate social inferences in the Eyes Test (Baron-Cohen, Wheelwright, Hill, Raste, & Plumb, 2001) and Voice Test (Golan, Baron-Cohen, Hill, & Rutherford, 2007), ability to generate reading inferences in the Inference subtest of the Watson-Glaser Critical Thinking Appraisal (Watson & Glaser, 1964), and their capacity for empathy from the Empathy Quotient …

School Stress, Academic Performance, And Coping In College Freshmen, Curtis Hill

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

The 2010 annual freshmen survey from the University of California Los Angeles stated that nearly half of all freshmen report having low to average levels of emotional health. This is the largest percentage of students in the low range of emotional health since the survey began over 25 years ago. Lower levels of mental and emotional health have been found to correlate with higher levels of stress. If students have high levels of stress and ineffective coping skills, this may negatively affect their academic performance. The purpose of my research was to understand how school stress, coping, and academic performance …

Evidence For Universal Grammar In Nicaraguan Sign Language And Development Of A Survey For Use With Practitioners, Martin González

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

This project involves examining the linguistic properties of Nicaraguan Sign Language (ISN) which developed rapidly after the creation of a deaf community in Nicaragua in the late 1970’s. Throughout the 1980s, as the language was passed from one cohort of signers to the next, the language became increasingly complex. ISN is one of the very few languages that linguists have had the chance to study as it was created and evolved. Therefore ISN provides a unique opportunity to study the origin of language, language evolution, and universal grammar. The theory of Universal Grammar claims that there are core principles that …

Factors That Explain The Use Of Complementary And Alternative Medicine In Undergraduates, Erin Sanchez

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Complementary and alternative medicine (CAM) has been determined to be highly effective in treating health problems and improving the lives of college students. However, if students are not using CAM therapies, they are not receiving the benefits that CAM could provide them. In a small city, where CAM may not be widely available, CAM use may be low. The current study attempted to determine if trends in student CAM use in large cities are similar in a small city. A survey was distributed to undergraduates at a mid-sized university in the Rocky Mountain region, yielding 217 completed surveys. The survey …

The Effects Of A Twelve-Week Aerobic And Cognitive Training Intervention On Cognitive Function In Cancer Survivors, Jesus Medrano, Jessica Brown, Daniel Shackelford, Corey Beebe, Alyse Brennecke

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

There are more than 100 clinically distinct types of cancer, each having their own symptoms and requiring a different method of cancer treatment. Despite current advances, the positive effects from treatment are often matched and outweighed by negative effects. One of the most prevalently reported symptoms is chemotherapy-related cognitive impairment (CRCI). CRCI has been reported to negatively affect memory, concentration, reaction time, attention, cognition, organizational skills, linguistic abilities, executive function, and activities of daily living. Purpose: To examine the effects of a 12-week aerobic and cognitive training on cognitive function in cancer survivors who have undergone or are currently …

Research Day And Research Excellence Awards Abstracts, Undergraduate Research Journal University Of Northern Colorado

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

For Research Day 2014, first and second place were awarded in the categories of oral presentations and poster presentations in three fields: Natural Sciences, Humanities and Arts, and Education/Behavioral Sciences and Business.

Understanding Reproductive Health Among Burmese Refugees In Greeley, Colorado: An Ethnographic Account, Alexandra Julia Krumtum

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

In the past four years, over 1,000 Burmese refugees have settled in Greeley, Colorado, but little is known about their conceptualizations of health or their experiences with local medical institutions. This paper investigates Burmese refugee women’s reproductive health beliefs and interactions with biomedical professionals. Through ethnographic interviews and participant observation, I show that a lack of mutual understanding between the two groups contributes to issues in communication and difficulties in promoting medical care. Medical anthropological research shows that culture has important implications for the experience and outcome of illness, as well as for the utilization of medical services and likelihood …

Fibroblast Growth Factor 23 Directly Targets Hepatocytes To Promote Inflammation In Chronic Kidney Disease, Saurav Singh

Open Access Dissertations

Chronic kidney disease (CKD) is a global health problem that affects 10-15% of the adult population worldwide and significantly increases the risk of death. Patients with CKD develop marked elevations in circulating levels of the phosphaturic hormone, fibroblast growth factor 23 (FGF23), which correlate with the stage of disease, and are associated with higher risk of mortality. Chronic inflammation is a hallmark of CKD. Circulating levels of inflammatory cytokines, such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) are significantly elevated in CKD patients and increase with disease progression. This inflammatory burden has been suggested to be …

Rwu Marine Scientists To Work Toward Reef Conservation At International Coral Reef Symposium, Jill Rodrigues

Featured News Story

In sharing their latest research, professors Andrew Rhyne and Koty Sharp collaborate on coral reef conservation strategies among 2,500 scientists and policy makers.

A Rare Case Of The Upper Extremity Diffuse Large B-Cell Lymphoma Mimicking Soft Tissue Sarcoma In An Elderly Patient, Aleksandra Mamorska-Dyga, Faisal Ronny, Carmelo Puccio, Humayun Islam, Delong Liu

NYMC Faculty Publications

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, with about 30% of new cases presenting with extranodal disease. Lesions originating from soft tissues of the upper extremities are extremely rare and may mimic other malignancies like sarcoma. We present a case of an elderly patient with right upper extremity (RUE) mass which was proven to be DLBCL instead of sarcoma. We emphasize the increasing need for investigating new therapeutic options for patients of extreme age and/or with underlying heart disease.

Ionic Liquid Extraction Unveils Previously Occluded Humic-Bound Iron In Peat Soil Pore Water, Timothy J. Veverica, Evan S. Kane, Amy Marcarelli, Sarah A. Green

Department of Biological Sciences Publications

Globally, peatland ecosystems store tremendous amounts of C relative to their extent on the landscape, largely owing to saturated soils which limit decomposition. While there is still considerable uncertainty regarding CO₂ production potential below the water table in peatland ecosystems, extracellular Fe reduction has been suggested as a dominant pathway for anaerobic metabolism. However, colorimetric methods commonly used to quantitate Fe and partition between redox species are known to be unreliable in the presence of complex humic substances, which are common in peatland pore water. We evaluated both the standard o-phenanthroline (o-P) Method and an ionic …

Ari Blumer Growth Of 2dimensional Transition Metal Dichalcogenides, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Farewell To A Mentor | College Of Engineering, Usu College Of Engineering

College of Engineering News

June 24, 2016 – After 22 years of service to Utah State University, College of Engineering Dean Dr. Christine Hailey will step down to begin a new leadership role in Texas and to be closer to family.

Desdemona's Dildo: Fetish Objects And Transitional Sex In Othello, Perry Guevara

Early Modern Culture

No abstract provided.

Empprior: Using Outside Empirical Data To Inform Branch-Length Priors For Bayesian Phylogenetics, John J. Andersen, Bradley J. Nelson, Jeremy M. Brown

Faculty Publications

© 2016 The Author(s). Background: Branch-length parameters are a central component of phylogenetic models and of intrinsic biological interest. Default branch-length priors in some Bayesian phylogenetic software can be unintentionally informative and lead to branch- and tree-length estimates that are unreasonable. Alternatively, priors may be uninformative, but lead to diffuse posterior estimates. Despite the widespread availability of relevant datasets from other groups, biologists rarely leverage outside information to specify branch-length priors that are specific to the analysis they are conducting. Results: We developed the software package EmpPrior to facilitate the collection and incorporation of relevant, outside information when setting branch-length …

Msspark: Implementation Of Molecular Simulation Queries Using Apache Spark, Parneet Kaur

USF Tampa Graduate Theses and Dissertations

Huge amount of data is being generated in almost every field and it cannot be avoided, rather is essential for the advancement of the field. Analysis of this data requires intensive computing power. Molecular Simulation is a powerful tool for understanding the behavior of natural systems. The simulation generates large amount data while observing the spatial and temporal relationships. The challenge is to handle the analytical queries that are often compute intensive.

Although various tools exist to tackle this problem, but in this paper we have tried an alternate approach that uses Apache Spark- a modern big data platform – …

Cellular And Molecular Features Of Developmentally Programmed Genome Rearrangement In A Vertebrate (Sea Lamprey: Petromyzon Marinus), Vladimir A. Timoshevskiy, Joseph R. Herdy, Melissa C. Keinath, Jeramiah J. Smith

Biology Faculty Publications

The sea lamprey (Petromyzon marinus) represents one of the few vertebrate species known to undergo large-scale programmatic elimination of genomic DNA over the course of its normal development. Programmed genome rearrangements (PGRs) result in the reproducible loss of ~20% of the genome from somatic cell lineages during early embryogenesis. Studies of PGR hold the potential to provide novel insights related to the maintenance of genome stability during the cell cycle and coordination between mechanisms responsible for the accurate distribution of chromosomes into daughter cells, yet little is known regarding the mechanistic basis or cellular context of PGR in …

Age- And Sex-Related Changes In Fasting Plasma Glucose And Lipoprotein In Cynomolgus Monkeys, Feng Yue, Guodong Zhang, Rongping Tang, Zhouquan Zhang, Liqiong Teng, Zhiming Zhang

Neuroscience Faculty Publications

Background: The age-related dysfunction of glucose and lipid metabolism has a long-standing relationship with cardiovascular and neurodegenerative disease. However, the effects of metabolic dysfunction on men and women are different. Reasons for these sex differences remains unclear. Cynomolgus monkeys have been used, in the past, for the study of human metabolic diseases due to their biologically proximity to humans. Nevertheless, few studies to date have focused on both age- and sex-related differences in glucose and lipid metabolism. The present study was designed to specifically address these questions by using a large cohort of cynomolgus monkeys (N = 1,399) including …

Modeling Population Growth And Response To Harvest For River Otters In Illinois, Clayton K. Nielsen

Journal of Contemporary Water Research and Education

Population modeling is an invaluable tool for predicting wildlife population dynamics and the effects of management. I created a state-space population model for unharvested river otters in the Illinois, Kaskaskia, and Wabash river basins in Illinois, and modeled future harvest at 5%, 10%, and 20% levels. River otter populations increased in the absence of harvest during 2000-2009 to 8,408 ± 1,934 individuals (λ = 1.11 ± 0.09). Harvest at 0%, 5%, 10%, and 20% levels resulted in continued population growth over time, with annual harvest numbers ranging from 446 - 1,786 in 2010 to 884 - 2,614 in 2014, depending …

Wildlife Habitat Is Similar At Mined Versus Unmined Sites 30 Years Following Surface Mining For Coal In Southern Illinois, Clayton K. Nielsen, Veronica L. Kelly

Journal of Contemporary Water Research and Education

Riparian ecosystems provide important habitat for wildlife and serve as corridors for animal movements. Surface mining activities clearly impact wildlife habitat by removing vegetation needed by wildlife. However, few studies have assessed longer-term success of habitat restoration in riparian ecosystems following surface mining. During 2012-13, we evaluated microhabitat quality at three stream segments restored 30 years ago following surface mining for coal and one unmined stream segment in Perry County, Illinois. Microhabitat differences were very minor among restored and control stream sites. Of the 41 habitat variables measured, 14 differed among sites, four of which were uncorrelated: canopy cover, overstory …

Mineralogical Transformations And Soil Development In Shale Across A Latitudinal Climosequence, Ashlee L.D. Dere, Timothy S. White, Richard H. April, Susan L. Brantley

Geography and Geology Faculty Publications

To investigate factors controlling soil formation, we established a climosequence as part of the Susquehanna-Shale Hills Critical Zone Observatory (SSHCZO) in central Pennsylvania, USA. Sites were located on organic matter-poor, iron-rich Silurian-aged shale in Wales, Pennsylvania, Virginia, Tennessee, Alabama, and Puerto Rico, although this last site is underlain by a younger shale. Across the climosequence, mean annual temperature (MAT) increases from 7 to 24°C and mean annual precipitation (MAP) ranges from 100 to 250 cm. Variations in soil characteristics along the climosequence, including depth, morphology, particle-size distribution, geochemistry, and bulk and clay mineralogy, were characterized to investigate the role of …

Scratching The Surface Or Digging Deeper: An Exploration Of Students' Attitudes Toward Their Ethnic Identity And Cultural Proficiency Among Undergraduate Students At Rowan University, Danielle Simcic

Theses and Dissertations

The purpose of this study was to gauge the attitudes of selected undergraduate students toward their ethnic identity, cultural knowledge, and cultural accountability at Rowan University. This study was conducted in the spring 2015 semester; freshmen residing in the Chestnut residence hall and seniors residing in the Rowan Boulevard apartment complex were surveyed. There was a total of 260 subjects surveyed over the course of three weeks. The subjects reported generally positive attitudes regarding their ethnic identity, cultural knowledge, and cultural accountability. The findings of this study revealed that Rowan University students indicated positive attitudes regarding their ethnic identity, cultural …

The Influence Of The Facial Pattern On Bone Density Pre And Post Orthodontic Treatment, Kristen M. Knecht

Master's Theses

No abstract provided.

Rutherford County High School Students Participate In Third Annual Science Academy At Gwu, Office Of University Communications

Gardner-Webb NewsCenter Archive

High school students from Rutherford County, N.C., are reporting that a unique week of their summer vacation that has given them new insight into the practical application of scientific principles. Through a grant from the Stonecutter Foundation (Spindale, N.C.), a dozen area teens participated in the third annual Science Academy, a program designed to offer enrichment in the subject of science and help students solidify skills in science, technology, engineering, and math (STEM). "The goal of the Science Academy is to provide a rich, practical experience in science with exposure to science related careers,” offered Jay Zimmer, biology instructor at …