Digital Commons Network^™

The Precarious Health Of Young Mexican American Men In South Texas, Cameron County Hispanic Cohort, 2004–2015, Gordon P. Watt, Kristina Vatcheva, Derek M. Griffith, Belinda M. Reininger, Laura Beretta, Michael Fallon, Joseph B. Mccormick, Susan P. Fisher-Hoch

School of Mathematical & Statistical Sciences Faculty Publications

Introduction

Hispanic men have higher rates of illness and death from various chronic conditions than do non-Hispanic men. We aimed to characterize the health of Mexican American men living on the US–Mexico border in South Texas and elucidate indications of chronic disease in young men.

Methods

We sampled all male participants from the Cameron County Hispanic Cohort, an ongoing population-based cohort of Mexican Americans in Brownsville, Texas. We calculated descriptive statistics and stratified the sample into 3 age groups to estimate the prevalence of sociodemographic, behavioral, and clinical factors by age group and evaluated differences between age groups.

Results

Obesity …

Psma Targeted Docetaxel-Loaded Superparamagnetic Iron Oxide Nanoparticles For Prostate Cancer, Prashanth K. B. Nagesh, Nia R. Johnson, Vijaya K. N. Boya, Pallabita Chowdhury, Shadi F. Othman, Vahid Khalilzad-Sharghi, Bilal B. Hafeez, Aditya Ganju, Sheema Khan, Stephen Behrman, Nadeem Zafar, Subhash C. Chauhan, Meena Jaggi, Murali M. Yallapu

School of Medicine Publications

Docetaxel (Dtxl) is currently the most common therapeutic option for prostate cancer (PC). However, adverse side effects and problems associated with chemo-resistance limit its therapeutic outcome in clinical settings. A targeted nanoparticle system to improve its delivery to and activity at the tumor site could be an attractive strategy for PC therapy. Therefore, the objective of this study was to develop and determine the anti-cancer efficacy of a novel docetaxel loaded, prostate specific membrane antigen (PSMA) targeted superparamagnetic iron oxide nanoparticle (SPION) (J591-SPION-Dtxl) formulation for PC therapy. Our results showed the SPION-Dtxl formulation exhibits an optimal particle size and zeta …

Molecular Mechanisms Autonomic Dysfunction And Impaired Cardiac Contractility In Critical Illness, Gl Ackland, J Whittle, A Toner, A Machhada, Et Al

Peninsula Medical School

Objectives: Molecular mechanisms linking autonomic dysfunction with poorer clinical outcomes in critical illness remain unclear. We hypothesized that baroreflex dysfunction alone is sufficient to cause cardiac impairment through neurohormonal activation of (NADPH oxidase-dependent) oxidative stress resulting in increased expression of G-protein coupled receptor kinase (GRK)-2, a key negative regulator of cardiac function. Design: Laboratory/clinical investigations. Setting: University laboratory/medical centers. Subjects: Adult rats; wild-type/NAPDH oxidase subunit-2 (NOX-2) deficient mice; elective surgical patients. Interventions: Cardiac performance was assessed by transthoracic echocardiography following experimental baroreflex dysfunction (BD, sino-aortic denervation) in rats and mice. Immunoblots assessed GPCR recycling proteins expression in rodent cardiomyocytes and …

Simultaneous Targeting Of Eph Receptors In Glioblastoma, S Ferluga, Cml Tomé, Dm Herpai, R D’Agostino, W Debinski

Peninsula Medical School

Eph tyrosine kinase receptors are frequently overexpressed and functional in many cancers, and they are attractive candidates for targeted therapy. Here, we analyzed the expression of Eph receptor A3, one of the most up-regulated factors in glioblastoma cells cultured under tumorsphere-forming conditions, together with EphA2 and EphB2 receptors. EphA3 was overexpressed in up to 60% of glioblastoma tumors tested, but not in normal brain. EphA3 was localized in scattered areas of the tumor, the invasive ring, and niches near tumor vessels. EphA3 co-localized with macrophage/leukocyte markers, suggesting EphA3 expression on tumor-infiltrating cells of bone marrow origin. We took advantage of …

Winthrop's Biochemistry Program Receives Seven-Year Accreditation, Winthrop University

Winthrop News 2016

• The degree track at Winthrop, first accredited in 2013, was the first in the nation to receive this designation by the society, and it has now been renewed through 2023.
• Winthrop’s biochemistry program exemplifies the university’s commitment to student learning and professional development and to faculty-student collaboration, said Debra Boyd, provost and executive vice president for academic affairs.

25th Annual Computational Neuroscience Meeting: Cns-2016, Various Authors

School of Engineering, Computing and Mathematics

Abstracts of the 25th Annual Computational Neuroscience Meeting: CNS-2016 Seogwipo City, Jeju-do, South Korea. 2–7 July 2016

The Intact Kunitz Domain Protects The Amyloid Precursor Protein From Being Processed By Matriptase-2, A-M Beckmann, K Glebov, J Walter, O Merkel, M Mangold, F Schmidt, C Becker-Pauly, M Gütschow, M Stirnberg

Peninsula Medical School

No abstract provided.

Detection Of Infectious Disease Outbreaks From Laboratory Data With Reporting Delays, A Noufaily, P Farrington, P Garthwaite, Et Al

Peninsula Medical School

Many statistical surveillance systems for the timely detection of outbreaks of infectious disease operate on laboratory data. Such data typically incur reporting delays between the time at which a specimen is collected for diagnostic purposes, and the time at which the results of the laboratory analysis become available. Statistical surveillance systems currently in use usually make some ad hoc adjustment for such delays, or use counts by time of report. We propose a new statistical approach that takes account of the delays explicitly, by monitoring the number of specimens identified in the current and past m time units, where m …

Reconstitution Of Munc18-Dependent Mast Cell Degranulation, Matthew Grant Arnold

Master's Theses

Mast cells are specialized secretory leukocytes that play diverse roles in the body, mediated by release of histamine and other pharmacologically active substances. Although offering essential protection in innate and adaptive immunity, mast cells are also essential to the progression of inflammatory diseases, including allergy and asthma, (Theoharides et al., 2012). Exocytosis of pro-inflammatory mast cell mediators in response to otherwise innocuous antigens relies on evolutionarily-conserved membrane fusion machinery. These proteins, called SNAREs are regulated by the Sec1/Munc18 (SM) protein family (Axle Lorentz, Baumann, Vitte, & Blank, 2012). Mast cells express three mammalian Munc18 isoforms (a, b, and c), which …

Genome-Wide Significant Loci For Addiction And Anxiety, Karen Hodgson, Laura Almasy, Emma E. M. Knowles, Jack W. Kent Jr., Joanne E. Curran, Thomas D. Dyer, Harald H. H. Goring, Rene L. Olvera, Peter T. Fox, Godfrey D. Pearlson, J. H. Krystal, Ravindranath Duggirala, John Blangero, David C. Glahn

School of Medicine Publications

Background

Psychiatric comorbidity is common among individuals with addictive disorders, with patients frequently suffering from anxiety disorders. While the genetic architecture of comorbid addictive and anxiety disorders remains unclear, elucidating the genes involved could provide important insights into the underlying etiology.

Methods

Here we examine a sample of 1284 Mexican-Americans from randomly selected extended pedigrees. Variance decomposition methods were used to examine the role of genetics in addiction phenotypes (lifetime history of alcohol dependence, drug dependence or chronic smoking) and various forms of clinically relevant anxiety. Genome-wide univariate and bivariate linkage scans were conducted to localize the chromosomal regions influencing …

Contact Process With Temporal Disorder, Hatem Barghathi, Thomas Vojta, José A. Hoyos

Physics Faculty Research & Creative Works

We investigate the influence of time-varying environmental noise, i.e., temporal disorder, on the nonequilibrium phase transition of the contact process. Combining a real-time renormalization group, scaling theory, and large scale Monte-Carlo simulations in one and two dimensions, we show that the temporal disorder gives rise to an exotic critical point. At criticality, the effective noise amplitude diverges with increasing time scale, and the probability distribution of the density becomes infinitely broad, even on a logarithmic scale. Moreover, the average density and survival probability decay only logarithmically with time. This infinite-noise critical behavior can be understood as the temporal counterpart of …

Adult Intimate Relationships: Linkages Between Interpersonal Acceptance-Rejection Theory And Adult Attachment Theory, Karen Ripoll-Núñez, Sonia Carrillo

Online Readings in Psychology and Culture

This paper focuses on the contributions of two lifespan-development theories to the study of adult intimate relationships. These are interpersonal acceptance-rejection theory (IPARTheory) and attachment theory. First, we focus on four major points of convergence and four points of divergence between theories in their understanding of intimate relationships in adulthood. Following this, we discuss each theory’s contributions to theoretical and empirical knowledge about adult intimate relationships, their modes of assessment, and the development of clinical interventions. Finally, we suggest possible future developments that could help to enrich both theories.

Saudi Arabia Science Teachers' Trends In Science Teaching Practices Of Teaching Related Scientific Activities According To Their Supervisors' Prospective And The Supervisors Estimates Of The Importance Of Such Practices, Abdulwali Aldahmash

Journal of Educational and Psychological Studies

This paper investigated the Trends in Science Teaching Practices in-classroom science related activities among general education science teachers in Saudi Arabia from their supervisors’ perspectives. In addition, the supervisor's point of view about the importance of scientific related instructional activities was assessed. The data were collected through a validated questionnaire (19 items), which was administered to a random sample of 60 science supervisors (32 males, 28 females) from various parts of the Kingdome of Saudi Arabia. The results revealed that supervisors judged classroom activities of science teachers as teacher-centered rather than student-centered. As for supervisors’ estimates of the importance of …

Teaching The Quandary Of Statistical Jurisprudence: A Review-Essay On Math On Trial By Schneps And Colmez, Noah Giansiracusa

Journal of Humanistic Mathematics

This review-essay on the mother-and-daughter collaboration Math on Trial stems from my recent experience using this book as the basis for a college freshman seminar on the interactions between math and law. I discuss the strengths and weaknesses of this book as an accessible introduction to this enigmatic yet deeply important topic. For those considering teaching from this text (a highly recommended endeavor) I offer some curricular suggestions.

Book Review: A New Index For Predicting Catastrophes: Poems By Madhur Anand, Joanne Growney

Journal of Humanistic Mathematics

This review explores Madhur Anand’s recent poetry collection from several points of view. One involves consideration of mathematical concepts and imagery in her poems. A second viewpoint takes into consideration Anand’s own field – she is a professor of environmental science with a focus on ecology. A third view considers the poems as art objects – words building pictures that offer to readers both insights and pleasures.

What Has An Impact On Grades? Instructor-Made Videos, Communication, And Timing In An Online Statistics Course, Regina Aragon, Indika P. Wickramasinghe

Journal of Humanistic Mathematics

This study investigates student success in an online introductory statistics class. We examine the impact of several variables: amount of time that a student watches instructor-made videos (IMV), the nature of communication between the student and the instructor, and the amount of time spent on completing the online assignments and exams on student grades in an introductory level online statistics course. Findings suggest that IMVs of short dur ation, the subject- related communication between the student and the instructor, and homework completion time have significant association with student performance. Though the average time spent on online exams does not show …

Bringing Students Back To Mathematics: Classroom Knowledge And Motivation, Giang-Nguyen T. Nguyen, Joel B. Goodin

Journal of Humanistic Mathematics

This paper reports part of a larger research study that investigated how teachers motivate students to learn mathematics at the college level. Findings from the study indicated that teachers have the power to influence and reinvigorate students who had given up learning mathematics. In the framework of Self-Determination Theory (SDT), the researchers analyzed five students’ motivational levels based on intrinsic and extrinsic motivation to see how each student was motivated by their teacher. Findings from the study could provide some directions for future research on students’ motivation to learn mathematics.

Book Review Essay: Not A Choice, Not A Job: Exposing The Myths About Prostitution And The Global Sex Trade, Tran Truong

Journal of International Women's Studies

Review of Not a Choice, Not a Job: Exposing the Myths about Prostitution and the Global Sex Trade, by Janice G. Raymond. Potomac Books, 2013.

Oriental Family Law: Case Study Within A Gendered-Citizenship/Inequality Perspective: From Concept To Analytical Status, Rania F. Al-Rabadi, Anas N. Al-Rabadi

Journal of International Women's Studies

This article presents key findings and empirical work of basic research in Bahrain in regards to active citizenship and gender equality where it analyses the claimed liberal citizenship. The article focuses on pre-existing inequality in the family code and also discusses a significant issue where there is a Sunni-Shi’ite division in Bahrain. This is relevant to citizenship and gender equality for how family codes are debated in regards to women’s rights within the legislative authority. Furthermore, this article analyses the parliamentary organizational structure which attributes and influences the legislation process and decision-making particularly on gender-friendly policies, where the legal system …

On The Relationship Between Gender Roles Attitudes, Religious Ideology And Familism In A Sample Of Adults In The United States, Carlos Siordia

Journal of International Women's Studies

Family and religious ideologies may influence gender role attitudes in the United States, where gender inequality persists. Research suggests that family and religious ideologies shape beliefs of how men and women should behave—where gender egalitarianism is lowest amongst those with strong family orientations and/or strong patriarchal religious ideologies. This article investigated if and how family and religious ideologies are related to gender role attitudes by using cross-sectional data from the Longitudinal Study of Generations (n=1,615; mean age=50; 61% female; 32% racial minorities). Results indicate a direct relationship between gender role ideology and the following: religious ideology and familism. Because gender …

Status Of Bahraini Women In The Banking And Financial Sector: Challenges And Opportunities, Adel Ismail Al-Alawi

Journal of International Women's Studies

The purpose of this study is to investigate the current status and the challenges of Bahraini women in the financial and banking sector; this sector is in continuous growth and needs to invest in human resources properly to attract talents. To enhance women’s access to senior positions in this sector, it must acknowledge the factors that influence women leadership, where the significance of this study stands out. The study presents how different factors affect the mainstreaming of women progressing to the top-level management. The study followed both quantitative and qualitative methods in data collection, and three different types of survey …

Empowering The Subaltern In Woman At Point Zero, Saddik Gohar

Journal of International Women's Studies

In the context of Western feminist theory, this paper critically explores Nawal El Saadawi's celebrated novel, Woman at Point Zero. The aim of this analysis is to establish a dialogue and outline the benefits of comparative feminist discourse with regard to patriarchal policies in the Middle East. The paper argues that El Saadawi challenges the hegemony of a traditionally phallocentric society empowered by religion and masculinity. In Woman at Point Zero, the author has effectively reinterpreted culturally dominated canons and deconstructed regressive traditions affiliated with patriarchal hegemony. Relying on her experience as a prison psychiatrist, El Saadawi interrogates a …

Separate Space: An Approach To Addressing Gender Inequality In The Workplace, Zuziwe Khuzwayo

Journal of International Women's Studies

Gender inequality in the workplace continues to be one of the most challenging issues to deal with in South African society where patriarchy still exists. This paper evaluates whether the South African Commercial Catering and Allied Workers Union’s (SACCAWU) separatist model for dealing with gender inequality have been successful. The union’s decision to create a ‘separate space’ for women within the union is analysed. Data collection comprised of an analysis of SACCAWU’s gender policy and material (including workshops, discussions and programmes run by the union). Participant observation and semi-structured interviews with 22 SACCAWU male and female members regarding gender policies, …

Natural Resources And Household Incomes Among Rural Women: Analysis Of Communities Domiciled Near National Parks In Rwanda, Edward Mutandwa, Seraphine Wibabara

Journal of International Women's Studies

Historically, national parks were developed along protectionist principles to stave off illegal extraction of plants and wildlife. However, there have been calls to involve local communities in sustainable management of natural resources in recent years. The main objective of this study was to examine the economic activities carried out by rural women located near the Virunga National Park (VNP) in Northern Rwanda. The research also determined the role of such activities in enhancing their financial condition. A total of 118 respondents were selected from Musanze District using a multi-stage sampling technique. Data was mainly collected through a structured questionnaire transcribed …

Southern American University Undergraduates' Attitudes Toward Intrauterine Insemination Undertaken By Women Of Differing Age, Marital Status And Sexual Orientation, Sara L. Sohr-Preston, Ashley K. Rohner, Bryce H. Lott

Journal of International Women's Studies

Undergraduate college students in the southern U.S. were presented with vignettes about a fictional woman seeking to become pregnant via intrauterine insemination (IUI). Participants were randomly assigned to conditions in which the woman described was 26 or 41 years old, and single, married to a man, or married to a woman. After reading the vignettes, participants rated their expectations of the prospective mother’s preparedness for parenting, ability to provide quality of life for a child, risk for pregnancy complications and achieving a healthy pregnancy. Results yielded marginally significantly (p = .05) lower expectations of achieving a healthy pregnancy when …

Led Lighting Upgrade Parking Lot: Ceramic Sculpture Building, James Grigg, Bryan Rountree

Sustainability Showcase (2014-2022)

LED Lighting Upgrade Parking Lot: Ceramic Sculpture Building

James Grigg, Director of Facilities Operations, Division of Facilities Services ($23,000)

Retrofit existing pole lighting in parking lot- Ceramic Sculpture- across from Biology Science Complex at Akins Boulevard. The lot’s outdoor lighting system consists of 8-40′ poles and 24-400 watt fixtures. The retrofit maintains existing light levels and reuse existing poles and provide state of-the-art Lighting Emitting Diode (LED) “high efficiency” outdoor lighting system.

A Hopeful Pedagogy To Critical Thinking, Mark C. Nicholas, Miriam Raider-Roth

International Journal for the Scholarship of Teaching & Learning

Elements of what we are calling a “hopeful pedagogy” emerged when faculty reflected on the question - Do you think your current approach to develop CT in students is successful? Faculty across disciplines and institutions used the word “hope” to characterize the outcome of their efforts. While attempting to disentangle the “hopeful pedagogy”, we found answers in (a) how faculty defined CT in disciplinary and non-disciplinary contexts; (b) a misalignment between faculty and institutional approaches to CT; (c) a disconnect between faculty and their own approaches to CT, and (d) logistical and curricular issues within general education programs that placed …

Becoming A Scientist: Using First-Year Undergraduate Science Courses To Promote Identification With Science Disciplines, Chloe Ruff, Brett D. Jones

International Journal for the Scholarship of Teaching & Learning

In this qualitative study, we examined how two professors (a physicist and biochemist) of first year college students perceived their students’ development of identification in biochemistry or physics and how they actively supported this development. The professors described students who entered college with different levels of domain identification and different expectations for their college science experience depending upon whether they were in a biochemistry or physics major. Although neither professor was familiar with research related to the concept of domain identification, their beliefs about their students’ identification and academic support strategies generally aligned with the Osborne and Jones (2011) model …

Moderation Analysis Of Bowel Function Among Nutrients And Physical Function Or Depression, As Well As Whether Bowel Function Is Related To Cognition In Older Adults, Jessie Alwerdt

USF Tampa Graduate Theses and Dissertations

As we age, the risk for gut issues, such as smooth muscle tone, may be an underlying indirect or direct cause or risk factor for many age-related issues, such as frailty. Consequences of decreased motility and depleted epithelial barrier may result in nutrient deficiencies that may increase the risk for malnutrition (Brownie, 2006). Further, there is increasing evidence that there is a gut-brain-axis relationship that may influence cognition and mental health issues, such as depression and anxiety. While there are relationships established, the interconnections of these factors have yet to be fully understood.

This dissertation examined several relationships specific to …

Admissions Report - Detailed Data - July 2016, Office Of Institutional Research & Effectiveness, Wright State University

Admissions Reports

Detailed report of applicants to Wright State including data on county of residency, intended major, and ethnicity for Fall Semester 2015.