Digital Commons Network^™

Motivational Situations Of Choice, Charles N. Elliott, Paul A. Story

The Kennesaw Journal of Undergraduate Research

The present research explores situations that demonstrate enhancing effects on motivation based on the amount of choice seen by individuals. Individuals who are intrinsically motivated see more choice in certain academic settings, including those that foster self-regulation and autonomy. Extrinsically motivated individuals are predicted to see more promise in reward and external regulation strategies. We identified six separate situations: a free will situation, a learning of materials situation, an instructor feedback situation, an extra credit situation, and two time-based situations. Four of these situations target a certain type of motivation, either intrinsic or extrinsic. The other two situations were used …

The Capacity Of Cognitive Control Estimated From A Perceptual Decision Making Task, Tingting Wu, Alexander J. Dufford, Melissa-Ann Mackie, Laura J. Egan, Jin Fan

Publications and Research

Cognitive control refers to the processes that permit selection and prioritization of information processing in different cognitive domains to reach the capacity-limited conscious mind. Although previous studies have suggested that the capacity of cognitive control itself is limited, a direct quantification of this capacity has not been attempted. In this behavioral study, we manipulated the information rate of cognitive control by parametrically varying both the uncertainty of stimul measured as information entropy and the exposure time of the stimuli. We used the relationship between the participants’ response accuracy and the information rate of cognitive control (in bits per second, bps) …

Eicosapentaenoic Acid Potentiates Brown Thermogenesis Through Ffar4-Dependent Up-Regulation Of Mir-30b And Mir-378*, Jiyoung Kim, Meshail Okla, Anjeza Erickson, Timothy P. Carr, Sathish Kumar Natarajan, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Emerging evidence suggests that n-3 polyunsaturated fatty acids (PUFA) promote brown adipose tissue thermogenesis. However, the underlying mechanisms remain elusive. Here, we hypothesize that n-3 PUFA promotes brown adipogenesis by modulating miRNAs. To test this hypothesis, murine brown preadipocytes were induced to differentiate the fatty acids of palmitic, oleate, or eicosapentaenoic acid (EPA). The increases of brown-specific signature genes and oxygen consumption rate by EPA were concurrent with up-regulation of miR-30b and 378 but not by oleate or palmitic acid. Next, we hypothesize that free fatty acid receptor 4 (Ffar4), a functional receptor for n-3 PUFA, modulates …

$8 Million Grant To Support Research To Repair Hearts With Bioengineered Patch, Jeff Hansen

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No abstract provided.

Volume Cxxxiv, Number 2, September 23, 2016, Lawrence University

The Lawrentian

No abstract provided.

Does Persistent Hiv Replication Explain Continued Lymphoma Incidence In The Era Of Effective Antiretroviral Therapy?, Jennifer Totonchy, Ethel Cesarman

Pharmacy Faculty Articles and Research

Non-Hodgkin lymphomas are highly increased in incidence in individuals infected with HIV, and this continues to be the case in spite of highly effective combined antiretroviral therapy (cART). New evidence has demonstrated that while successful virtual recovery of CD4 counts and elimination of HIV from peripheral blood can be achieved with cART, viral replication can still occur in lymphoid tissues. In addition, recent studies have suggested that adipose tissue provides an additional reservoir for HIV-infected macrophages and T lymphocytes even in the context of successful cART therapy. In this review article, we discuss possible mechanisms leading to the development of …

Twenty-Four Years Of Teaching Science Has Its Rewards, Susan Dumais

UNH Today Archive

No abstract provided.

Identification Of Control Targets In Boolean Molecular Network Models Via Computational Algebra, David Murrugarra, Alan Veliz-Cuba, Boris Aguilar, Reinhard Laubenbacher

Mathematics Faculty Publications

Background: Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into another, more desirable, state through an intervention, such as a drug or other therapeutic treatment. The identification of such strategies is typically based on a mathematical model of the process to be altered through targeted control inputs. This paper focuses on processes at the molecular level that determine the state of an individual cell, involving signaling or gene regulation. The mathematical model type …

Characteristics Of Algan/Gan Hemts For Detection Of Mig, Hasina Huq, Hector Trevino Ii, Jorge Castillo

Electrical and Computer Engineering Faculty Publications

The aim of this research work is to analyze the surface characteristics of an improved AlGaN/GaN HEMT biosensor. The investigation leads to analyze the transistor performance to detect human MIG with the help of an analytical model and measured data. The surface engineering includes the effects of repeatability, influence of the substrate, threshold shifting, and floating gate configuration. A numerical method is developed using the charge-control model and the results are used to observe the changes in the device channel at the quantum level. A Self-Assembled Monolayer (SAM) is formed at the gate electrode to allow immobilization and reliable crosslinking …

Immunomodulators As Therapeutic Agents In Mitigating The Progression Of Parkinson's Disease, Bethany Grimmig, Josh Morganti, Kevin Nash, Paula C. Bickford

Sanders-Brown Center on Aging Faculty Publications

Parkinson’s disease (PD) is a common neurodegenerative disorder that primarily afflicts the elderly. It is characterized by motor dysfunction due to extensive neuron loss in the substantia nigra pars compacta. There are multiple biological processes that are negatively impacted during the pathogenesis of PD, and are implicated in the cell death in this region. Neuroinflammation is evidently involved in PD pathology and mitigating the inflammatory cascade has been a therapeutic strategy. Age is the number one risk factor for PD and thus needs to be considered in the context of disease pathology. Here, we discuss the role of neuroinflammation within …

Sperm Morphometrics, Spermatogenesis, And Testicular Cycle Of The Rough Greensnake (Opheodrys Aestivus), John Douglas Konvalina

Student Theses and Dissertations

Spermatogenesis in ophidians is understudied, with little information on the rough greensnake, Opheodrys aestivus available. A cell wheel showing the chronological development of germ cell stages for this species was constructed. Sperm morphometrics were completed and compared with those of Nerodia rhombifer, the diamondback watersnake. Both species had similar sperm head length, while Opheodrys aestivus had significantly longer total sperm length. Total sperm length was positively correlated (r = 0.997, p < 0.001) with sperm tail length. Seminiferous tubule diameter and seminiferous tubule epithelial height were measured from Arkansas (AR) specimens and compared with those of Alabama (AL) specimens and AR measurements were found to be significantly greater in length. Future studies of O. aestivus need to investigate the testicular cycle in other parts of its geographic distribution to see if the monthly pattern is consistent and sperm morphometrics should be examined for other species within the family Colubridae.

Identification Of Control Targets In Boolean Molecular Network Models Via Computational Algebra, David Murrugarra, Alan Veliz-Cuba, Boris Aguilar, Reinhard Laubenbacher

Mathematics Faculty Publications

Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into another, more desirable, state through an intervention, such as a drug or other therapeutic treatment. The identification of such strategies is typically based on a mathematical model of the process to be altered through targeted control inputs. This paper focuses on processes at the molecular level that determine the state of an individual cell, involving signaling or gene regulation. The mathematical model type considered …

Female Adult Aedes Albopictus Suppression By Wolbachia-Infected Male Mosquitoes, James W. Mains, Corey L. Brelsfoard, Robert I. Rose, Stephen L. Dobson

Entomology Faculty Publications

Dengue, chikungunya and zika viruses are pathogens with an increasing global impact. In the absence of an approved vaccine or therapy, their management relies on controlling the mosquito vectors. But traditional controls are inadequate, and the range of invasive species such as Aedes albopictus (Asian Tiger Mosquito) is expanding. Genetically modified mosquitoes are being tested, but their use has encountered regulatory barriers and public opposition in some countries. Wolbachia bacteria can cause a form of conditional sterility, which can provide an alternative to genetic modification or irradiation. It is unknown however, whether openly released, artificially infected male Ae. albopictus can …

September 23, 2016, The Dakota Student

The Dakota Student

No abstract provided.

Merrimack College Record, Merrimack College

Merrimack College Record

No abstract provided.

Multiobjective Guided Priors Improve The Accuracy Of Near-Infrared Spectral Tomography For Breast Imaging, Jinchao Feng, Shudong Jiang, Junqing Xu, Yan Zhao, Brian W. Pogue, Keith D. Paulsen

Dartmouth Scholarship

An image reconstruction regularization approach for magnetic resonance imaging-guided near-infrared spectral tomography has been developed to improve quantification of total hemoglobin (HbT) and water. By combining prior information from dynamic contrast enhanced (DCE) and diffusion weighted (DW) MR images, the absolute bias errors of HbT and water in the tumor were reduced by 22% and 18%, 21% and 6%, and 10% and 11%, compared to that in the no-prior, DCE- or DW-guided reconstructed images in three-dimensional simulations, respectively. In addition, the apparent contrast values of HbT and water were increased in patient image reconstruction from 1.4 and 1.4 (DCE) or …

The Parthenon, September 23, 2016, Lexi Browning

The Parthenon

The Parthenon, Marshall University’s student newspaper, was published by students Monday through Friday during the regular semester and weekly on Thursdays during the summer. Due to budgetary constraints, beginning with the 2016 Fall semester, the newspaper is only published two days a week. Physical issues are printed on Tuesdays and Fridays. The editorial staff is responsible for the news and the editorial content.

September 23, 2016, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Magic School Bus Presents: The Human Body, Liz Kazandzhy

Children's Book and Media Review

Jump on the Magic School Bus and come explore the human body! Ms. Frizzle is ready to take you on a ride starting in the inside of a cell and ending with an overview of what makes a body run and how to take care of it. You’ll ride right on through all the vital body parts (skin, hair, nails, bones, muscles), senses (touch, eye, ear, mouth, nose), organs (brain, heart, lungs), and systems (nervous, digestive, circulatory), making for a truly exciting journey.

Next Generation Mass Spectrometry Tools For Characterizing The Protein Interactome, Peter Dimaggio

Amgen Seminar Series in Chemical Engineering

Significant technological advancements in liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics over the past decade have facilitated the high-throughput and quantitative analysis of proteins, with as many as 10,000 proteins identified in a single sample. However, it is now appreciated that detecting changes in protein abundance alone is insufficient for characterizing disease pathology, and that context-specific molecular interactions between proteins with other biomolecules (i.e. other proteins, nucleic acids and metabolites) are the key drivers in disease development and progression. In order to shed further insight into this protein “interactome”, more sophisticated reagents and tools are required that interface with mass …

Large-Scale Computational Screening And Machine Learning Approaches To Drug Discovery, Bryce K. Allen

Open Access Dissertations

Biological information continues to grow exponentially fueled by massive data generation projects such as the Human Genome Project, The Cancer Genome Atlas (TCGA), and the Library of Integrated Network-based Cellular Signatures (LINCS). Unprecedented amounts and varieties of data (big data) have the potential to bring enormous scientific advances. Such data-driven research relies on advanced computational approaches for data integration and analysis. While bioinformatics encompasses many fields, the focus of my research has been to predict small molecule chemicals that interact with protein targets of interest and could, ultimately, become therapeutically useful drugs. Drug resistance in newly diagnosed tumors is often …

Spartan Daily, September 22, 2016, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2016

Volume 147, Issue 11

Western News, September 22, 2016, Western Michigan University

Western News (1972-2018)

Story Highlights: Two more facilities open amid fanfare, Trustee Johnston lays out process for presidential search, WMU employees; dependents get tuition discount at Cooley, Campuswide award winners to be feted at Fall Convocation, On Campus with La Shaunda Webb

Ua12/2/1 College Heights Herald, Vol. 92, No. 10, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news.

• Ares, Nicole. Man Airlifted After Fight on Center Street Late Saturday – Cory Johnson
• WKU Pulls Deal with Medical Center, Will Bid Out Project
• Dick, Jacob. WKU Police Report on Racist Letters Shows Possible Motive – Michelle Jones
• Collins, Emma. Alumni Survey Receives Few Minority Responses
• Hinderbrandt, Laryn. Department Receives Community Health Grant – Institute for Rural Health
• Keltner, Bryson. Students Work, Save Lives with Global Brigades
• King, Jennifer. Editorial Cartoon re: Chicken Strips
• Ronkainen, Millie. Mother Teresa’s Work of Hope, Comfort
• Hicks, Sarah. How to Stay Stylish While …

Eelgrass Distribution And Biomass In The Great Bay Estuary For 2015, Frederick T. Short

PREP Reports & Publications

See also: "Eelgrass/Macroalgae Discussion Primer for TAC Activities 2016-2017" http://scholars.unh.edu/prep/355

Eelgrass (Zostera marina L.) is an essential habitat for the Great Bay Estuary (GBE) because it is the basis of an estuarine food web that supports many of the recreationally, commercially and ecologically important species in the estuary and beyond. Eelgrass provides food for ducks, geese and swans, as well as food, nursery habitat, and shelter for juvenile fish and shellfish. Eelgrass filters estuarine waters and improves water clarity, removing both nutrients and suspended sediments from the water column; its roots and rhizomes bind and hold sediments in place, thereby …

Nation And History In The Mobilization Of Collective Identity Among Lgbt Czechs, Cleo M. Spencer

Claremont-UC Undergraduate Research Conference on the European Union

Social movement theories are often built on Western and US-centric understandings of civic life and the values that underpin it. Studying participation in the LGBT movement in Prague, Czech Republic provides one context for complicating such underlying assumptions. Within theory on mobilization, collective identity is said to act as a conduit for developing personal investment through individuals’ identities. Interviews with LGBT people in Prague, however, show that there is little sense of or desire for collective identity among these potential participants. Czech national history contextualizes respondents’ distinct descriptions of the role of civic life and activism, value of private life, …

Minutes, College Of Liberal Arts Faculty Meeting, Thursday, September 22, 2016, Rollins College

The College of Liberal Arts Faculty Minutes

No abstract provided.

Palmitoyl Acyltransferase Dhhc21 Mediates Endothelial Dysfunction In Systemic Inflammatory Response Syndrome, Richard S. Beard Jr.

Biomedical Research Institute Publications and Presentations

Endothelial dysfunction is a hallmark of systemic inflammatory response underlying multiple organ failure. Here we report a novel function of DHHC-containing palmitoyl acyltransferases (PATs) in mediating endothelial inflammation. Pharmacological inhibition of PATs attenuates barrier leakage and leucocyte adhesion induced by endothelial junction hyperpermeability and ICAM-1 expression during inflammation. Among 11 DHHCs detected in vascular endothelium, DHHC21 is required for barrier response. Mice with DHHC21 function deficiency (Zdhhc21^dep/dep) exhibit marked resistance to injury, characterized by reduced plasma leakage, decreased leucocyte adhesion and ameliorated lung pathology, culminating in improved survival. Endothelial cells from Zdhhc21^dep/dep display blunted barrier dysfunction and …

Assessing Aquatic System Metabolism Response To Disturbance, Traci Carmen Hudson

Student Theses and Dissertations

Until recently, agricultural drainage ditches and urban stream systems have been underrepresented within aquatic research studies. This underrepresentation has led to gaps in knowledge within the area of ecosystem structure and function, characteristics of agriculture and urban stream stressors, and management strategies for those streams. Many of the factors (increased nutrients, changes to the quantity and composition of organic carbon inputs, light alterations, and sedimentation) that impair water bodies associated with agricultural drainage and urbanization also influence stream processes. Stream organic matter production and consumption measured as ecosystem metabolism, is a fundamental process comprised of gross primary production (GPP) and …

Nih Awards More Than $150 Million For Research On Environmental Influences On Child Health, Staff

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No abstract provided.