Digital Commons Network^™

Bioengineered Cell Niche For Skeletal Muscle Regeneration, Nicole Whittern

The Journal of Purdue Undergraduate Research

No abstract provided.

Measurement Of Copper Deficiency In Humans: Ccs As A Novel Biomarker Of Copper Status In Bariatric Surgery Patients, Emily Watson

The Journal of Purdue Undergraduate Research

Bariatric surgery is a popular and effective treatment for obesity. However, an unfavorable consequence for patients who have had bariatric surgery is copper (Cu) deficiency. Current screening methods used for Cu deficiency are neither sensitive nor specifi c enough to diagnose Cu deficiency or detect changes in Cu status. The purpose of this research is to determine if concentrations of copper chaperone for superoxide dismutase (CCS) in erythrocytes are associated with serum Cu concentrations in bariatric surgery patients, by assessing whether changes in CCS concentrations can be observed in response to altering Cu status when patients are supplemented with Cu …

Synthesis And Characterization Of A Series Of Uranium(Iv) Species: Investigating Coordination With A Redox Innocent Triamine Ligand, Selena L. Staun

The Journal of Purdue Undergraduate Research

Investigation of uranium(IV) complexes chelated by a tridentate amine, H₃RITA (H₃RITA = (MesNHCH₂CH₂)2NH, Mes = 2,4,6-trimethylphenyl), has afforded novel new compounds with the potential for small molecule activation. Deprotonation of H₃RITA with two equivalents of benzyl potassium affords K₂HRITA, which upon reaction with uranium tetrachloride forms (THF)₂UCl₂(HRITA) (THF = tetrahydrofuran). The labile THF molecules are easily substituted for triphenylphosphine oxide (OPPh₃), a much stronger ligand, forming (Ph₃PO)UCl₂(HRITA). Installation of a cyclopentadienyl ligand, Cp* (Cp* = 1,2,3,4,5-pentamethylcyclopentadienyl), was achieved …

Anisotropy Scanning: Novel Imaging Analysis For Beef Tenderness, Derico Setyabrata

The Journal of Purdue Undergraduate Research

Providing consistently high-eating-quality meat products to consumers is crucial for the meat industry. Inconsistent meat tenderness has been identified as one of the major quality-related challenges for the meat industry. Thus, development of a precise and consistent method to predict meat tenderness will greatly benefit the meat industry by enabling it to ensure a constant high-quality meat supply to consumers. A novel noninvasive anisotropic image scanning technology has been recently developed to evaluate and predict microstructural and physicochemical changes in muscle. Thus, the objective of this study was to evaluate the efficacy of the novel anisotropic imaging system in assessing …

Degeneration Of Neuronal Mitochondria In Parkinson’S Disease: Mitochondrial Turnover In Neuromuscular Junctions Of Parkin Mutants., Kenny Nguyen

The Journal of Purdue Undergraduate Research

The accumulation of dysfunctional or damaged mitochondria in neurons has been linked to the pathogenesis of many neurodegenerative diseases, including Parkinson’s disease. It has been proposed that the Parkinson’s-related proteins PINK1 and Parkin regulate mitochondrial quality control by selectively targeting depolarized mitochondria for autophagic degradation, a process known as mitophagy. The compartmentalization of mitochondrial turnover in neurons still remains unclear, but evidence suggests that mitochondria are locally degraded in the distal axon and perhaps in the neuromuscular junctions (NMJs). To study this, intact Drosophila nervous systems were analyzed in vivo by performing gentle dissections on third instar larvae to expose …

Full Issue 30a(1/4)

International Journal of Speleology

No abstract provided.

Full Issue 29b(1/4)

International Journal of Speleology

No abstract provided.

Full Issue 27(1/4)

International Journal of Speleology

No abstract provided.

Full Issue 26(1/2)

International Journal of Speleology

No abstract provided.

Board Of Trustees Meeting Minutes 2016-09-30, Bowling Green State University

Board of Trustees Meeting Minutes

The official meeting minutes of Bowling Green State University's Board of Trustees.

Phi Beta Kappa Honor Society: Raising Visibility On Campus., Kristina Wirtz

Academic Leadership Academy

WMU’s Phi Beta Kappa Chapter

• Phi Beta Kappa is the nation’s oldest and most prestigious honor society, founded at the College of William & Mary in 1776.
• Western Michigan University is among 10% of American colleges and universities to host a chapter of Phi Beta Kappa.
• Our chapter, Theta of Michigan, was founded in 1997 after more than a decade of efforts by WMU faculty and administrators. We are a WMU “point of pride.”
• Phi Beta Kappa celebrates and advocates excellence in the liberal arts and sciences.

The Problem: PBK’s Low Profile on Campus

1)Low student response rate:

• Students at …

Fall Convocation 2016 Program, Office Of Faculty Development

Fall Convocation

A program for the Fall 2016 convocation, giving information on programs to improve student learning, including faculty and staff awards, State of the University Address, aspects of the Teaching & Learning Bash, and Teaching with Technology and Assessment in Action.

2016-09-30, Morehead State University. Board Of Regents.

Morehead State Board of Regents Agenda Books and Meeting Minutes

Meeting minutes of the Board of Regents for September 30, 2016.

The Effect Of Long-Term Proton Pump Inhibitor Use On Frailtysyndrome In Elderly Patients, Stephanie Dewi, Purwita W. Laksmi, Ari Fahrial Syam

Jurnal Penyakit Dalam Indonesia

Introduction. Frailty syndrome, the newest elderly health predictor, associated with higher morbidity and mortality. PPI are often used in elderly due to presence of upper gastrointestinal complaints, and relates with polypharmacy as one of the risk factor for frailty syndrome. There is no study of the relationship between long term PPI use and frailty syndrome in elderly. Methods. A case control study included subjects 60 years and above with good cognitive status. All subjects with history of hypersensitivity of PPI were excluded. Elderly who were frail based on FI-40 item were defined as cases, while individuals that were not frail …

Change Of Interleukin-6, C-Reactive Protein And Soluble Vascularcell Adhesion Molecule-1 Concentrations In Hemodialysispatients With Reprocessed Dialyzer, Pringgodigdo Nugroho, Aida Lydia, Marulam Mp Panggabean

Jurnal Penyakit Dalam Indonesia

Introduction. Cardiovascular disease is a major cause of morbidity and mortality in hemodialysis patients. In addition to traditional cardiovascular risk factors, non-traditional cardiovascular risk factors such as inflammation were also involved. Reprocessed dialyzer has been showed to induce less inflammation than new dialyzer, but data in diacetate cellulose membrane have not been presented. Methods. Twenty hemodialysis (HD) patients were enrolled. Pre and post study design was conducted to know post dialysis concentration changes of interleukin 6 (IL-6), C-reactive protein (CRP) and soluble vascular cell adhesion molecule-1 (sVCAM-1) at reuse 0, 5 and 10. Patients were recruited if medically stable, on …

An Item Response Theory Analysis Of Emotional Expressivity Measures, Melissa K. Matheys

Theses and Dissertations

The understanding of psychometric properties of emotional expressivity measures is often limited to rudimentary statistics. The present study investigated, in depth, the psychometric properties of four measures of emotional expressivity (the Self-Concealment Scale, the Distress Disclosure Index, the Emotional Expressivity Scale, and the Emotion Regulation Questionnaire – Suppression subscale). Item response theory (IRT) analyses suggested that recoded versions of the measures’ Likert scales may be beneficial in practice as well as the deletion of some measures’ items. IRT analyses of the four measures of emotional expressivity provide more information than classical test theory statistics about how to implement these measures …

Ben Domain Protein Elba2 Can Functionally Substitute For Linker Histone H1 In Drosophila In Vivo, Na Xu, Xingwu Lu, Harsh Kavi, Alexander V. Emelyanov, Travis J. Bernardo, Elena Vershilova, Arthur I. Skoultchi, Dmitry V. Fyodorov

Publications and Research

Metazoan linker histones are essential for development and play crucial roles in organization of chromatin, modification of epigenetic states and regulation of genetic activity. Vertebrates express multiple linker histone H1 isoforms, which may function redundantly. In contrast, H1 isoforms are not present in Dipterans, including D. melanogaster, except for an embryo-specific, distantly related dBigH1. Here we show that Drosophila BEN domain protein Elba2, which is expressed in early embryos and was hypothesized to have insulator-specific functions, can compensate for the loss of H1 in vivo. Although the Elba2 gene is not essential, its mutation causes a disruption of normal internucleosomal …

Admissions Report - Detailed Data - September 2016, Office Of Institutional Research & Effectiveness, Wright State University

Admissions Reports

Detailed report of applicants to Wright State including data on county of residency, intended major, and ethnicity for Fall Semester 2017.

Volume Cxxxiv, Number 3, September 30, 2016, Lawrence University

The Lawrentian

No abstract provided.

Undocumented And Unafraid: The Emergence Of An Undocumented Movement And Its Impact On Immigration Policy, The Dream Act, Daca, Dapa, And Family Unification, William V. Flores Ph.D.

Journal of Family Strengths

Undocumented and Unafraid: The Emergence of an Undocumented Movement and Its Impact on Immigration Policy, the DREAM Act, DACA, DAPA, and Family Unification

This articles traces the efforts of undocumented students throughout the U.S. to come forward and reveal their status, claim rights, and participate in political and community engagement efforts typical of U.S. citizens by becoming active in student and community organizations, shaping political discourse on immigrant rights, and expanding our conception of what it means to be ‘American.’ Their social activism reflects a strong desire to be full-members of this society. Undocumented youth are deeply concerned about family …

Electrochemical Nanoprobes For Electron Transfer Kinetics And Electrocatalysis Study, Yun Yu

Dissertations, Theses, and Capstone Projects

The studies of electrochemical processes on the nanoscale have led to a significant progress in understanding of electrochemical mechanisms and characterization of nanomaterials in the fields of energy, catalysis, and biological research. Electrochemical experiments at nanoscale require the fabrication and characterization of nanometer-sized electrochemical probes. The main advantages of the nanoprobes include very fast mass-transfer rate, high signal-to-noise ratio and extremely fine spatial resolution of electrochemical imaging. In the course of my Ph.D. research, different types of electrochemical probes were developed for measuring electron-transfer kinetics, probing single catalytic nanoparticles and sampling ultra-small volume of liquids.

We developed methodologies to fabricate …

Development Of New Radiolabeling Methods And Insights On Ionizing Radiation Interactions With Nanoparticles, Travis Shaffer

Dissertations, Theses, and Capstone Projects

Nanoparticles are often combined with radionuclides for various applications, ranging from waste remediation to imaging and therapy in the medical field. The overarching aim of this body of work is two-fold. The first aim is development of new radiolabeling methods for various nanoparticles that allow stable attachment of a variety of imaging and therapeutic radionuclides. The second portion more fully describes mechanisms of interaction between ionizing radiation and nanoparticles.

The following advancements will be presented in this dissertation: i) a new radiolabeling method for silica and silica-based nanoparticles that does not require the use of specific chelators, with both radiochemical …

Institutionalizing Environmental Justice: Race, Place, And The National Environmental Policy Act, Keith K. Miyake

Dissertations, Theses, and Capstone Projects

In this dissertation, I examine ways that the US National Environmental Policy Act of 1969 (NEPA) and its primary enforcement mechanism, the Environmental Impact Assessment (EIA) process, have reshaped the state as a site for racial and environmental conflict by institutionalizing a particular form of environmental justice within governmental decision making processes. Combining archival methods and legal analysis, I develop three case studies involving community struggles over the social production of space that each engage the EIA process to different effect. The case studies were selected based on what they reveal about the ways that the environmental justice framework intersects …

Critical Youth Participatory Action Research To Reimagine Environmental Education With Youth In Urban Environments, Marissa E. Bellino

Dissertations, Theses, and Capstone Projects

This work addresses ways to actively engage youth, particularly those growing up in urban contexts, in the rapidly expanding field of urban environmental education (EE). By inviting youth into the urban EE discourse, this study created opportunities to redefine what EE could look like when it is built on relevance to youth daily lives and is locally situated in urban settings. A critical urban environmental pedagogy, as conceptualized in this dissertation, brings together critical pedagogy and youth participatory action research to investigate the diversity of urban neighborhoods by youth who live there. These investigations reveal neoliberal urbanization processes and their …

My Mother Needs Me! Is It Possible To Stay Connected While Being My Own Person? The Object Relations Of The Latina “Dutiful Daughter”, Juliana Martinez

Dissertations, Theses, and Capstone Projects

Background: Latinas are culturally expected to be “dutiful daughters” establishing strong attachments and adhering to the traditional values characterized by loyalty, cooperation, respect and interdependence within family members. Conventional Latina mother-daughter bonds, therefore, are expected to be exceptionally close. Healthy mother-daughter closeness can be a valuable source of support while closeness without differentiation from the mother may result in a lack of independence and poor interpersonal and personal growth. Mutuality of autonomy, a dimension of object relations (OR) theory, focuses on the progression of separation – individuation from developmentally normative fused representations in infancy to highly differentiated self-other representations as …

Three Essays On The Effects Of Childbearing On Economic Well-Being And Health, Ramazan Onur Altindag

Dissertations, Theses, and Capstone Projects

Chapter 1: Couples in Turkey exhibit son preference through son-biased differential stopping behavior that does not cause a sex ratio imbalance in the population. Demand for sons leads to lower ratios of boys to girls in larger families but higher ratios in smaller families. Girls are born earlier than their male siblings, and son-biased fertility behavior is persistent in response to decline in fertility over time and across households with parents from different backgrounds. Parents use contraceptive methods to halt fertility following a male birth. The sibling sex composition is associated with gender disparities in health. Among third- or later-born …

Role Of Hnrnp A1 In The Regulation Of Hdm2 Gene Expression, Heriberto Moran

Dissertations, Theses, and Capstone Projects

hnRNP A1 is one of the most abundant and ubiquitously expressed member of hnRNPs (Heterogenous Nuclear Ribonucleoproteins) family of proteins that play multiple roles in gene expression by participating in major steps in the processing of nascent RNA transcripts 1. It is involved in mRNA biogenesis mechanisms such as the transcription, splicing, stability, export and translation of cellular and viral transcripts. The functions of hnRNP A1 extend to the processing of microRNAs, telomere maintenance and DNA repair 1. Our previous studies have shown that hnRNPA1 had reduced protein level and increased cytoplasmic accumulation in senescent human diploid fibroblasts 2,10. Our …

Sustainable Molecular Gelators: Beta-D-Glucoside Derived Structuring Agents And Their Material Application, Julian R. Silverman

Dissertations, Theses, and Capstone Projects

Though molecular gelators may by synthesized and formulated into gels following a variety of methods, it should serve that the most valued methods may utilize renewable and waste resources and follow sustainable procedures. Molecular gelators are systems capable of structuring liquids into solid-like materials and they represent a class of surfactant and amphiphilic materials which posses the capability to be not only useful in their ability to form gels, but multifunctional in the ability to respond smartly to a variety of stimuli. Thus there is an interest in the development of sustainable molecular gelators capable of being applied to applications, …

Phylogeny, Systematics And Biogeography Of Short-Tailed Opossums (Didelphidae: Monodelphis), Silvia E. Pavan

Dissertations, Theses, and Capstone Projects

Short-tailed opossums (genus Monodelphis) comprise the most species-rich genus of New World marsupials, with 25 currently recognized species. Monodelphis comprise small, terrestrial species collectively widespread in South America, which makes the group potentially informative about biogeographic processes that have shaped the continental fauna. The genus exhibits striking variation in several phenotypic characters, notably pelage coloration, behavior, and reproductive strategies. This diversity is unique among Neotropical marsupials, and makes the group particularly interesting to investigate the evolution and the adaptive significance of phenotypic trait variation. Despite this potential, missing knowledge on phylogeny and basic taxonomy precludes broader studies on evolution …

Some 2-Categorical Aspects In Physics, Arthur Parzygnat

Dissertations, Theses, and Capstone Projects

2-categories provide a useful transition point between ordinary category theory and infinity-category theory where one can perform concrete computations for applications in physics and at the same time provide rigorous formalism for mathematical structures appearing in physics. We survey three such broad instances. First, we describe two-dimensional algebra as a means of constructing non-abelian parallel transport along surfaces which can be used to describe strings charged under non-abelian gauge groups in string theory. Second, we formalize the notion of convex and cone categories, provide a preliminary categorical definition of entropy, and exhibit several examples. Thirdly, we provide a universal description …