Digital Commons Network^™

Responses Of Antarctic Marine And Freshwater Ecosystems To Changing Ice Conditions, Maciej K. Obryk, Peter T. Doran, Ari S. Friedlaender, Michael N. Gooseff, Wei Li, Rachael M. Morgan-Kiss, John C. Priscu, Oscar Schofield, Sharon E. Stammerjohn, Deborah K. Steinberg, Hugh W. Ducklow

Faculty Publications

© 2016 The Author(s) 2016. Polar regions are warming more rapidly than lower latitudes, and climate models predict that this trend will continue into the coming decades. Despite these observations and predictions, relatively little is known about how polar ecosystems have responded and will continue to respond to this change. Two Long-Term Ecological Research (LTER) sites, located in contrasting environments in Antarctica, have been studying marine and aquatic terrestrial ecosystems for more than two decades. We use data from these research areas to show that the extent and thickness of ice covers are highly sensitive to short- and long-term climate …

New Circumspection Of The Genus Gamochaeta (Asteraceae, Gnaphalieae) Inferred From Nuclear And Plastid Dna Sequences, Estrella Urtubey, Alicia López, María A. Chemisquy, Arne A. Anderberg, Carlos M. Baeza, Néstor D. Bayón, Leonardo P. Deble, Andrés Moreira-Muñoz, Guy L. Nesom, Mac H. Alford, Luciana Salomón, Susana E. Freire

Faculty Publications

Gamochaeta (tribe Gnaphalieae, Asteraceae) is composed of ca. 60 species primarily distributed in tropical and subtropical America. Within the tribe Gnaphalieae, the genus is characterized by capitula arranged in spikes or head-like clusters, few hermaphroditic central florets, truncate style branches with apical sweeping trichomes, pappus bristles connate at the base into a ring falling as a unit, and achenes with globose twin trichomes. Previous molecular phylogenetic studies have suggested the paraphyly of the genus, but have not provided a basis for redefining generic limits due to incomplete taxon sampling. To address this problem, DNA sequences from the plastid (trn …

A Snapshot Of The Microbiome Of Ambylomma Tuberculatum Ticks Infesting The Gopher Tortoise, An Endangered Species, Khemraj Budachetri, Daniel Lyle Gaillard, Jaclyn Bo Williams, Nabanita Mukherjee, Shahid Karim

Faculty Publications

The gopher tortoise tick, Amblyomma tuberculatum, has a unique relationship with the gopher tortoise, Gopherus polyphemus, found in sandy habitats across the southeastern United States. We aimed to understand the overall bacterial community associated with A. tuberculatum while also focusing on spotted fever group Rickettsia. These tortoises in the Southern Mississippi region are a federally threatened species; therefore, we have carefully trapped the tortoises and removed the species-specific ticks attached to them. Genomic DNA was extracted from individual ticks and used to explore overall bacterial load using pyrosequencing of bacterial 16S rRNA on 454-sequencing platform. The spotted fever group …

Alleged Insanity: Frank Johnson Sr., Racial Injustice, And The Failure Of The Mental Health Care System In South Carolina, Jonathon P. Johnson

Senior Theses

This thesis is about Frank Johnson Sr. and the circumstances that led to his downfall as a farmer and father of six, to his tragic death in the isolation of a racially segregated mental institution 18 miles away from his home. Using his life and incarceration at the South Carolina State Park mental health facility, I argue that racial injustice contributed to his tragic death and the woefully inadequate treatment thousands of African Americans in South Carolina received during Jim Crow. Additionally, I argue that the tragic circumstances around my great grandfather’s institutionalization and death were part of an enduring …

The Write Stuff - Autumn 2016 (Vol. 13, No. 4), Research Medical Library

Write Stuff 2016

• Using calendar dates in case reports
• How does an author’s leaving an institution affect in-progress manuscripts?
• What trainees should know before submitting manuscripts to the Department of Scientific Publications
• EQUATOR Network offers more than 300 specialized reporting guidelines
• Autumn and winter schedule for the Research Medical Library webinar program
• Unusual terms used in scientific writing and publishing: Red Journal, Gray Journal, and other colorful nicknames

Cedar Waxwings, Michael L. Avery, Anthony G. Duffiney

Wildlife Damage Management Technical Series

Prevention and control of cedar waxwing (Bombycilla cedrorum) damage to small fruits such as blueberry, cherry, and strawberry is vexing to growers in many parts of the United States. Cedar waxwings (Figure 1) travel in flocks and descend in large numbers on berry crops, especially during winter and migration. In short feeding bouts, waxwings eat, peck, or knock substantial amounts of fruit from the plants. These frugivores are difficult to discourage once they become established at a given location. Harassment early and often using pyrotechnics or other sudden noisemakers can help prevent flocks from being established. The most effective preventative …

Utrgv Commencement – Fall 2016, The University Of Texas Rio Grande Valley

UTRGV Commencement Programs

No abstract provided.

Trimethylamine N-Oxide And Mortality Risk In Patients With Peripheral Artery Disease, Vichai Senthong, Zeneng Wang, Yiying Fan, Yuping Wu, Stanley L. Hazen, W.H. Wilson Tang

Mathematics and Statistics Faculty Publications

Background: Production of the proatherogenic metabolite, trimethylamine N-oxide (TMAO), from dietary nutrients by intestinal microbiota enhances atherosclerosis development in animal models and is associated with atherosclerotic coronary artery disease in humans. The utility of studying plasma levels of TMAO to risk stratify in patients with peripheral artery disease (PAD) has not been reported. Methods and Results: We examined the relationship between fasting plasma TMAO and all-cause mortality (5-year), stratified by subtypes of PAD and presence of coronary artery disease in 935 patients with PAD who underwent elective angiography for cardiac evaluation at a tertiary care hospital. Median plasma TMAO was …

Where Sovereign Immunity Ends And Liability Begins: A Functional Restructuring Of The United States Military Tort Compensation Scheme, Jordon Parker

Cardozo Journal of International and Comparative Law

The note critiques the current system of tort claims against the United States, particularly in cases involving the military, arguing that it is overly complex and fails to provide adequate compensation for injured individuals. It proposes replacing the existing tort system with a no-fault compensation scheme, similar to New Zealand’s Accident Compensation Act 2001, to better address the needs of victims.

Associations Between Major Depression, Health-Risk Behaviors, And Medication Adherence Among Hiv-Positive Adults Receiving Medical Care In Georgia, Rachel Culbreth, Shanta R. Dube, David Maggio

Journal of the Georgia Public Health Association

Background: There are approximately 1.2 million people in the United States living with HIV, and 25.6% of HIV-positive adults suffer from depression. The purpose of this study is to examine the contribution of depression to substance use and medication adherence among HIV-positive adults receiving medical care for HIV in Georgia.

Methods: Secondary data with a probability sample of 775 HIV-positive adults who took part in the 2009-2013 Georgia Medical Monitoring Project (MMP) were analyzed. Descriptive analyses and multivariate logistic regressions were conducted to assess relationships between depression and current cigarette smoking, injection drug use, other non-injection drug use, and medication …

Determinants Of Adherence To Nutrition- Related Cancer Prevention Guidelines Among African American Breast Cancer Survivors, Lindsey A. Ramirez, Yunmi Chung, Wonsuk Yoo, Brittney Fontenot, Benjamin E. Ansa, Mary S. Whitehead, Selina A. Smith

Journal of the Georgia Public Health Association

Background: Mortality rate for breast cancer is higher among African American (AA) women than for women of other racial/ethnic groups. Obesity, also higher among AA women, may increase the risk of breast cancer development and recurrence. Lifestyle factors such as healthy nutrition can reduce the rate of obesity and breast cancer. This study examined the determinants of adherence to nutrition-related cancer prevention guidelines among AA breast cancer survivors.

Methods: AA breast cancer survivors (n=240) were recruited from a breast cancer support group to complete a lifestyle assessment tool for this cross-sectional study. Chi-square test and ordinal logistic regression analysis were …

The Association Of Stress With Anxiety And Depression: Evidence From A Community Health Needs Assessment, Nicole La Tournous, Grace Bagwell-Adams

Journal of the Georgia Public Health Association

Background: Mental illness affects approximately 1 in 5 Americans, making mental health an important area of study for public health. Much research has been conducted on two of the most prevalent mental health disorders, anxiety and depression. However, the association of stress with these disorders, especially specific types of stress (e.g., financial, health, relationship), has been under-studied at the local level. This study aimed to gain insight into the relationship between stress, anxiety, and depression in Athens-Clarke County, Georgia.

Methods: Data collected in the 2015 Athens-Clarke County Community Health Needs Assessment were analyzed using linear regression models to explore the …

The Zika Virus In The United States: A Comprehensive Review, Daniel R. Lindsey, Martin H. Greenberg

Journal of the Georgia Public Health Association

Background: With a series of outbreaks spanning the globe, the Zika virus has transitioned, in a short time, from an obscure virus to a public health emergency. Locally transmitted Zika has reached the United States, leading to increased concern regarding further transmission and the potential impact on public health.

Methods: The present study was conducted to examine the propagation and effects of Zika in the United States by reviewing published literature regarding Zika in conjunction with updates from the Centers for Disease Control and Prevention. To gauge the regional response, including prevention and control efforts, interviews were conducted with public …

Air Pollution, Physical Activity, And Markers Of Acute Airway Oxidative Stress And Inflammation In Adolescents, Emily Pasalic, Matthew J. Hayat, Roby Greenwald

Journal of the Georgia Public Health Association

Background: The airway inflammatory response is likely the mechanism for adverse health effects related to exposure to air pollution. Increased ventilation rates during physical activity in the presence of air pollution increases the inhaled dose of pollutants. However, physical activity may moderate the relationship between air pollution and the inflammatory response. The present study aimed to characterize, among healthy adolescents, the relationship between dose of inhaled air pollution, physical activity, and markers of lung function, oxidative stress, and airway inflammation.

Methods: With a non-probability sample of adolescents, this observational study estimated the association between air pollution dose and outcome measures …

Ipulse: October 2016, Lynn University

Student Newspapers

Issues:

• October 3, 2016
• October 5, 2016
• October 10, 2016
• October 12, 2016
• October 14, 2016
• October 17, 2016
• October 19, 2016
• October 21, 2016
• October 24, 2016
• October 26, 2016
• October 28, 2016
• October 31, 2016

Immunomodulatory Effects Of Psyllium Extract On Helicobacter Pylori Interaction With Gastric Epithelial Cells., Javed Yakoob, Wasim Jafri, Malik Hassan Mehmood, Z Abbas, Kanwal Tariq

Section of Gastroenterology

Natural plant product Psyllium has anti-inflammatory activity that can modulate the function of cytokines. We determined the effect of Psylliumhusk extract on interleukin (IL)-8 and NF-κB secretion by gastric epithelial cells in response to Helicobacter pylori Human gastricadenocarcinoma cell line (AGS) cells were pretreated with Psyllium extract in different concentrations before H pylori infection. Cell culture supernatant was analyzed for IL-8 and NF-κB by ELISA. RNA from cells was used for real-time polymerase chain reaction for messenger RNA expression of IL-8. Psyllium extract 5 and 10 μg/mL markedly (P < .001) lowered basal IL-8 by 64.71% and 74.51%, respectively, and H pylori-stimulated IL-8 was also (P < .001) lowered by 41.67% and 66.67%, respectively. Psyllium 5 and 10 μg/mL also reduced (P < .0001) cagA-positive H pylori-induced IL-8 mRNA expression by 42.3% and 67.6%, respectively. Psyllium also reduced (P = .0001) NF-κB in response to H pylori strains confirming its role as an anti-inflammatory agent.

The Effect Of Acute Supplementation Of Sodium Bicarbonate And Caffeine On Anaerobic Running Performance, Kyle E. Witherbee

Theses

Sodium bicarbonate (NaHCO3) and caffeine are two sport supplements that have been widely explored for their possible ergogenic effects during exercise. Few studies have looked at sodium bicarbonate and caffeine supplementation together and no studies have included a running test.

Purpose: The purpose of this study was to examine the effect of sodium bicarbonate and caffeine, both independent and synergistically, on a field-based intermittent sprint test.

Methods: Three men and 10 women, of recreational fitness level, completed this research study. On four separate visits, participants consumed a supplement solution in randomized order of 300mg/kg NaHCO3, 5mg/kg caffeine, 300mg/kg …

Association Between Combat, Morally Injurious Experiences, Spiritual Injury, And Alcohol Use Among Active Duty Military Personnel And Veterans, Allison T. Robbins

Psychology Theses & Dissertations

Literature has supported that, along with physical and psychological injuries, combat profoundly impacts veterans’ moral and spiritual belief systems and may contribute to negative health behaviors. Moral injury is a developing construct related to negative consequences associated with war-zone stressors that transgress military veterans’ deeply held values and belief systems. Additionally, spiritual injury addresses negative responses to an event that damages their relationship with God, self, and others, and alienates an individual from that which gives meaning to their lives. The purpose of the present study was to examine the relationship between combat exposure, morally injurious experiences (MIEs), spiritual injury, …

Potential Impacts Of Climate Change On Photochemistry Of Zostera Marina L., Billur Celebi

OES Theses and Dissertations

Seagrasses account for approximately 10% of the ocean’s total carbon storage, although photosynthesis of seagrasses is carbon limited at today’s oceanic pH. Therefore, increasing atmospheric CO₂ concentration, which results in ocean acidification/carbonation, is predicted to have a positive impact on seagrass productivity. Previous studies have confirmed the positive influence of increasing CO₂ on photosynthesis and survival of the temperate eelgrass Zostera marina L., but the acclimation of photoprotective mechanisms in this context has not been characterized. This study aimed to quantify the long-term impacts of ocean acidification on photochemical control mechanisms that promote photosynthesis while simultaneously protecting …

Bioenergetics: Experimental Demonstration Of Excess Protons And Related Features, Haitham A. Saeed

Chemistry & Biochemistry Theses & Dissertations

Over the last 50 years, ever since the Nobel-prize work of Peter Mitchell’s Chemiosmotic theory, the question whether bioenergetics energy transduction occurs through localized or delocalized protons has been a controversial issue among scientists. Recently, a proton-electrostatics localization hypothesis was formulated which may provide a new and clear understanding of localized and delocalized proton-coupling energy transduction in many biological systems. The aim of this dissertation was to test this new hypothesis.

To demonstrate the fundamental behavior of localized protons in a pure water-membrane-water system in relation to the newly derived pmf equation, excess protons and excess hydroxyl anions were generated …

Design Of Drug Nano-Carriers For Study Of Multidrug Resistance In Single Live Cells, Pavan Kumar Cherukuri

Chemistry & Biochemistry Theses & Dissertations

Multidrug resistance (MDR) exists in both prokaryotic and eukaryotic cells. MDR is responsible for ineffective treatment of a wide range of diseases, such as infections and cancer. The ATP-binding cassette (ABC) membrane transporters (efflux pumps) are one of the largest and most diverse super-families of membrane proteins found in all living organisms, ranging from bacteria to humans. All ABC transporters share a common structure of four core domains; two transmembrane domains (TMD) with variable sequence and topology and two nucleotide-binding domains (NBD) with conserved sequences. Conventional methods for the study of the efflux functions are radioactively labeled substrates and fluorescent …

Coarse Root Biomass And Architecture: Applications Of Ground Penetrating Radar, John Claude Bain

Biological Sciences Theses & Dissertations

The effectiveness of ground penetrating radar (GPR) to identify and quantify coarse roots was tested in a mixed-oak forest in Southeastern Virginia using experimental pits and locally excavated root segments. GPR was found to be highly dependent on low soil moisture levels as it is unable to differentiate root structures if they possess similar moisture content as their surrounding soil. Likewise, GPR was unable to identify simulated dead roots. This does not alter the effectiveness of GPR to measure living coarse root biomass, but does present the potential for underestimation of carbon storage in coarse root structures, as a dead …

Prejudice Toward Atheists In The United States As Related To Perceived Prevalence, Wanda D. Brooks

Psychology Theses & Dissertations

By manipulating mortality salience (MS) in place of life-threatening events to stimulate death-related thoughts, the current research contributes to the body of research supporting Terror Management Theory. It was hypothesized that religious participants should exhibit cultural worldview defense by scoring higher in anti-atheist prejudice following the MS manipulation than would those in the control condition. Further, this research extends the current research into Terror Management Theory as a cause for conflict among out-groups and explores its effects on cultural worldviews in the area of prejudice toward atheists. This includes examining how the perception of an increasing prevalence of atheists contributes …

Bioactivation Of Trimethoprim To Protein-Reactive Metabolites In Human Liver Microsomes., Jennifer Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, J Steven Leeder, Robert P. Hanzlik

Manuscripts, Articles, Book Chapters and Other Papers

The formation of drug-protein adducts via metabolic activation and covalent binding may stimulate an immune response or may result in direct cell toxicity. Protein covalent binding is a potentially pivotal step in the development of idiosyncratic adverse drug reactions (IADRs). Trimethoprim (TMP)-sulfamethoxazole (SMX) is a combination antibiotic that commonly causes IADRs. Recent data suggest that the contribution of the TMP component of TMP-SMX to IADRs may be underappreciated. We previously demonstrated that TMP is bioactivated to chemically reactive intermediates that can be trapped in vitro by N-acetyl cysteine (NAC), and we have detected TMP-NAC adducts (i.e., mercapturic acids) in the …

The Urea Carboxylase And Allophanate Hydrolase Activities Of Urea Amidolyase Are Functionally Independent, Yi Lin, Cody J. Boese, Martin St. Maurice

Biological Sciences Faculty Research and Publications

Urea amidolyase (UAL) is a multifunctional biotin-dependent enzyme that contributes to both bacterial and fungal pathogenicity by catalyzing the ATP-dependent cleavage of urea into ammonia and CO₂. UAL is comprised of two enzymatic components: urea carboxylase (UC) and allophanate hydrolase (AH). These enzyme activities are encoded on separate but proximally related genes in prokaryotes while, in most fungi, they are encoded by a single gene that produces a fusion enzyme on a single polypeptide chain. It is unclear whether the UC and AH activities are connected through substrate channeling or other forms of direct communication. Here, we use …

Destabilization Of The Ornithine Decarboxylase Mrna Transcript By The Rna-Binding Protein Tristetraprolin, Shannon L. Nowotarski, Sofia Origanti, Suzanne Sass-Kuhn, Lisa M. Shantz

Biological Sciences Faculty Research and Publications

Ornithine decarboxylase (ODC) is the first and usually rate-limiting enzyme in the polyamine biosynthetic pathway. In a normal physiological state, ODC is tightly regulated. However, during neoplastic transformation, ODC expression becomes upregulated. The studies described here show that the ODC mRNA transcript is destabilized by the RNA-binding protein tristetraprolin (TTP). We show that TTP is able to bind to the ODC mRNA transcript in both non-transformed RIE-1 cells and transformed Ras12V cells. Moreover, using mouse embryonic fibroblast cell lines that are devoid of a functional TTP protein, we demonstrate that in the absence of TTP both ODC mRNA stability and …

Dipl 6277 Na Global Health, Bioterrorism, And International Security, Yanzhong Huang Phd

Diplomacy Syllabi

In today’s world, international trade and travel threaten epidemics by transporting and spreading infectious disease globally at jet speed. The growing risk of exposure to infectious disease, coupled with the threat of bioterrorism, creates a situation in which health and security are interacting with greater frequency and intensity. This development parallels efforts to redefine the concept of security to encompass new global challenges. To what extent does health fit this new security agenda? What are the major linkages between health and security? Should non-communicable diseases be framed as problems that demand response from the national security community? How does the …

Abiotic Factors Contributing To The Survival Of Three Tick Species In Southeastern Virginia, Amblyomma Americanum (Lone Star Tick), Dermacentor Variabilis (American Dog Tick), And Amblyomma Maculatum (Gulf Coast Tick), Lindsey A. Bidder

Biological Sciences Theses & Dissertations

Amblyomma americanum, Amblyomma maculatum, and Dermacentor variabilis are hard-bodied ticks in the Hampton Roads area of southeastern Virginia. This study consisted of two field projects focused on these tick species. To estimate the off-host survival of local tick species, a capture-mark-recapture (CMR) study was performed. An environmental survival study was performed to quantify the ability of these three tick species to survive in situ. Four field sites were used in the Hampton Roads region covering a variety of habitat types and vegetation; specifically two drier, upland field sites and two flood-prone sites. CMR was conducted from May through …

Why Public Health Policy Should Redefine Consent To Assault And The Intentional Foul In Gladiator Sports, Jennifer A. Brobst

Journal of Law and Health

This article considers in Part II the status and influence of public health research regarding the safety risks of gladiator sports and the field’s tendency to neglect the sports’ recognized medical and mental health benefits. In Part III, the historical trends in judicial interpretation of the scope of the criminal consent defense and civil doctrines of a privilege of consent to assault and assumption of the risk in the sports context are addressed. Finally, Part IV asserts the need to reform the civil and criminal defenses to intentional misconduct in sports through agency, judicial, and statutory reform, for the purpose …

Down To The Felt: How Ohio's Lackluster Statutory Scheme Gambles With The Lives Of Mothers And Innocent Children, Jim Rainone

Journal of Law and Health

This article examines three facets of the pregnant prisoner prenatal and post-birth care issue. First, it examines the injustice that pregnant prisoners are subjected to. Next, it examines other states' statutory regimes to identify adequate and inadequate features. Specifically, it examines the Pennsylvania regime because of its relevance and reputation for being the most accommodating to these women. Finally, it proposes a statutory regime for Ohio that provides mandatory care standards, means of accomplishing mandatory care, penalties for both the institution and its individual actors when care is not provided--and shows how a statutory regime without these changes puts mothers …