Digital Commons Network^™

The Rock, Fall/Winter 2016 (Vol. 86, No. 1), Whittier College

The Rock

No abstract provided.

Impacting Middle School Girls’ Interest And Achievement In Math: Research On A Piloted Pre-Engineering Program, Linda S. Paslov

NERA Conference Proceedings 2016

A female’s college and career goals may ultimately be restricted by declining interest and achievement in mathematics that originates during her pre-high school years. This researcher examined how a piloted pre-engineering program in one eighth grade team impacted adolescent girls’ interest and achievement. The results suggest that Project Lead The Way impacted both boys’ and girls’ interest and achievement in mathematics. As this educational research was undertaken to assist local decision makers in supporting or opposing a district adoption of PLTW for all middle schoolers, effectively communicating the results to the various stakeholders in an engaging, useful manner was paramount.

Sharing A Successful Practice: A Life-Enhancing And Life-Saving Approach To Health Education, Joanne M. Crossman

NERA Conference Proceedings 2016

No abstract provided.

2016 October - Veteran's Voice Newsletter, Office Of Military And Veteran's Services, East Tennessee State University

Veteran's Voice Newsletter [2016-2017]

No abstract provided.

Tribeta Hosts Biological Sciences Research Fair, Oct. 11, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Phlip Peptide Interaction With A Membrane Monitored By Saxs, Theyencheri Narayanan, Dhammika Weerakkody, Alexander G Karabadzhak, Michael Anderson, Oleg A. Andreev, Yana Reshetnyak

Physics Faculty Publications

The pH (Low) Insertion Peptides (pHLIP® peptides) find application in studies of membrane-associated folding, since spontaneous insertion of these peptides is conveniently triggered by varying pH. Here we employed small angle X-ray scattering (SAXS) to investigate WT pHLIP® peptide oligomeric state in solution at high concentrations and monitor changes in liposome structure upon peptide insertion into the bilayer. We established that even at high concentrations (up to 300 μM) WT pHLIP® peptide at pH 8.0 does not form oligomers higher than tetramers (which exhibit concentration-dependent transfer to monomeric state as it was shown previously). This finding has significance for medical …

Comparative Study Of Tumor Targeting And Biodistribution Of Ph (Low) Insertion Peptides (Phlip® Peptides) Conjugated With Different Fluorescent Dyes, Ramona Cosmina Adochite, Anna Moshnikova, Jovana Golijanin, Oleg A. Andreev, Natallia Katenka, Yana Reshetnyak

Physics Faculty Publications

Purpose

Acidification of extracellular space promotes tumor development, progression, and invasiveness. pH (low) insertion peptides (pHLIP^® peptides) belong to the class of pH-sensitive membrane peptides, which target acidic tumors and deliver imaging and/or therapeutic agents to cancer cells within tumors.

Procedures

Ex vivo fluorescent imaging of tissue and organs collected at various time points after administration of different pHLIP^® variants conjugated with fluorescent dyes of various polarity was performed. Methods of multivariate statistical analyses were employed to establish classification between fluorescently labeled pHLIP^® variants in multidimensional space of spectral parameters.

Results

The fluorescently labeled pHLIP^® variants …

Targeted Imaging Of Urothelium Carcinoma In Human Bladders By An Icg Phlip Peptide Ex Vivo, Jovana Golijanin, Ali Amin, Anna Moshnikova, Joseph M. Brito, Timothy Y. Tran, Ramona Cosmina Adochite, Gregory O. Andreev, Troy Crawford, Donald Engelman, Oleg A. Andreev, Yana Reshetnyak, Dragan Golijanin

Physics Faculty Publications

Bladder cancer is the fifth most common in incidence and one of the most expensive cancers to treat. Early detection greatly improves the chances of survival and bladder preservation. The pH Low Insertion Peptide (pHLIP® peptide) conjugated with a near infrared fluorescent dye (ICG) targets low extracellular pH allowing visualization of malignant lesions in human bladder carcinoma ex vivo. Cystectomy specimens obtained after radical surgery were immediately irrigated with non-buffered saline and instilled with a solution of the ICG pHLIP® construct, incubated, and rinsed. Bladders were subsequently opened and imaged, the fluorescent spots were marked, and a standard pathological analysis …

Circulation, Vol. 22, No. 1, Center For Coastal Physical Oceanography, Old Dominion University, Mike Dinniman

CCPO Circulation

Fall 2016 issue of CCPO Circulation featuring article "I have to Do What to the Model? How Did I Get Here, Part ll" by Mike Dinniman.

Longwood Magazine 2016 Fall, Longwood University

Alumni Newsletters & Bulletins

No abstract provided.

Joint Force Quarterly 83 (4th Quarter, October 2016), National Defense University Press

Joint Force Quarterly ARCHIVES

No abstract provided.

1. Types Of Alignment: Presentations & Demos Assignment, Sarah O'Leary-Driscoll

Sequence Alignments

Pairwise Alignment: DNA

Pairwise Alignment: Protein

Multiple Sequence Alignment: DNA

Multiple Sequence Alignment: Protein

Neurotransmitter, Fall 2016, George Washington Institute For Neuroscience, Neurological Institute, George Washington University Hospital

Neurotransmitter

No abstract provided.

Uni Schedule Of Classes, Fall 2016, University Of Northern Iowa

UNI Schedule of Classes

A listing and schedule of the courses being taught as well as policies and procedures concerning attending classes at the University of Northern Iowa.

Water Current, Volume 48, No. 4, Fall 2016

Water Current Newsletter

Water and natural resources tour examines Platte River basin June 27-29, 2017

Research workshops are local to global; efforts on grants, collaborations continue

Pertinacity Volume 2 Issue 2, Yuri Hosokawa

Pertinacity

No abstract provided.

Kennedy Lecture | Leading Scholar On Love Human Attraction, Oct. 11, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Physics Colloquium | Flatland That Folds And Oscillates Making Wrinkles And Drumheads With Graphene, Oct. 14, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Food In Cuba Spring Break Info Session, Oct. 5 630 Pm, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pbio Colloquium | Systematic And Evolutionary Studies On Violets More Going On Than We Thought, Oct. 21, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Geology Colloquium | The Marine Methane Hydrate Reservoir, Oct. 7, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pbio Colloquium | Inositol Phosphate Signaling In Plants, Oct. 14, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Science Café | Why’D I Do That? Exploring Decision-Making Processes, Oct. 19, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Chemistry Colloquium | Protein Lipidmodification From Chemical Biology To Proteinbased Nanoscale Materials, Oct. 10, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Environmental Plant Biology Internship Symposium, Oct. 21, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Newsletter Fall 2016, Christy M. Wyandt, Katelyn Miller

Newsletters of the Graduate School

No abstract provided.

The Search, The Jackson Laboratory

Search Magazine

No abstract provided.

Consumer Product Chemicals In Indoor Dust: A Quantitative Meta-Analysis Of U.S. Studies, Susanna D. Mitro, Robin Dodson, Veena Singla, Gary Adamkiewicz, Angelo F. Elmi, Monica Tilly, Ami R. Zota

Environmental and Occupational Health Faculty Publications

Indoor dust is a reservoir for commercial consumer product chemicals, including many compounds with known or suspected health effects. However, most dust exposure studies measure few chemicals in small samples. We systematically searched the U.S. indoor dust literature on phthalates, replacement flame retardants (RFRs), perfluoroalkyl substances (PFASs), synthetic fragrances, and environmental phenols and estimated pooled geometric means (GMs) and 95% confidence intervals for 45 chemicals measured in ≥3 data sets. In order to rank and contextualize these results, we used the pooled GMs to calculate residential intake from dust ingestion, inhalation, and dermal uptake from air, and then identified hazard …

Epigenetics Of Lipid Phenotypes, Sergi Sayols-Baixeras, Marguerite R. Irvin, Donna K. Arnett, Roberto Elosua, Stella W. Aslibekyan

Epidemiology and Environmental Health Faculty Publications

Dyslipidemia is a well-established risk factor for cardiovascular disease, the main cause of death worldwide. Blood lipid profiles are patterned by both genetic and environmental factors. In recent years, epigenetics has emerged as a paradigm that unifies these influences. In this review, we have summarized the latest evidence implicating epigenetic mechanisms—DNA methylation, histone modification, and regulation by RNAs—in lipid homeostasis. Key findings have emerged in a number of novel epigenetic loci located in biologically plausible genes (eg, CPT1A, ABCG1, SREBF1, and others), as well as microRNA-33a/b. Evidence from animal and cell culture models suggests a complex interplay …

Laudato Si': A Commentary, Gerard Magill

Spiritan Horizons

No abstract provided.