Digital Commons Network^™

Fluselenamyl: A Novel Benzoselenazole Derivative For Pet Detection Of Amyloid Plaques (Aβ) In Alzheimer's Disease, Nigam Rath, G.S.M. Sundaram, Dhruva Dhavale, Julie Prior, Ping Yan, John Cirrito, Richard Laforest, Nigel Cairns, Jin-Moo Lee, Paul Kotzbauer, Vijay Sharma

Chemistry & Biochemistry Faculty Works

Fluselenamyl (5), a novel planar benzoselenazole shows traits desirable of enabling noninvasive imaging of Aβ pathophysiology in vivo; labeling of both diffuse (an earlier manifestation of neuritic plaques) and fibrillar plaques in Alzheimer’s disease (AD) brain sections, and remarkable specificity for mapping Aβ compared with biomarker proteins of other neurodegenerative diseases. Employing AD homogenates, [18F]-9, a PET tracer demonstrates superior (2–10 fold higher) binding affinity than approved FDA tracers, while also indicating binding to high affinity site on Aβ plaques. Pharmacokinetic studies indicate high initial influx of [18F]-9 in normal mice brains accompanied by rapid clearance in the absence of …

Chemistry Colloquium | Discovering New Antiinfectives From Underexplored Environmental Microorganisms, Nov. 21, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Geology Colloquium | No Cursing Crying No Cookies Women Trailblazers In Geomorphology, Nov. 4, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Struggles For Access To Justice In Appalachia Panel, Nov. 17, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Chemistry Colloquium | Walking In The Woods Of Metabolites With Mass Spectrometry, Nov. 28, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pbio Colloquium | Recognition And Processing Of Ubiquitin Chains By The Proteasome, Nov. 18, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pbio Colloquium | Wildlife Conservation In A Changing World, Nov. 4, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Fever Of Unknown Origin In Patient After Left Ventricular Assist Device Implantation, Eugenia Raichlin, Sara Varnado, John Y. Um, Michael J. Moulton, Ronald Zolty Dr

The VAD Journal

Mechanical circulatory support (MCS) is a lifesaving procedure in patients with refractory cardiogenic shock. Despite improvement in surgical techniques, ICU care and restored hemodynamics, some patients on MCS remain severely debilitated due to multiple medical problems, including infections, respiratory failure, de-conditioning and nutritional deficits.

Here we present a case of a patient with persistent high degree fever, devastating muscle weakness, and elevated lactate dehydrogenase (LDH) level, who dramatically responded to treatment with vitamin B 12.

Affirmative Action Dan Penguatan Partisipasi Politik Kaum Perempuan, Mudiyati Rahmatunnisa

Jurnal Wacana Politik

Despite various existence of ratified UN Conventions and other international and national policies, women’s political participation has still been considered week. They remain substantially underrepresented in the position of political decision making. In other words, political sphere is still male-dominated. Needless to say, formal political equality statements are not enough. It needs more actions to make it into reality. One potential measure, among other things, is affirmative action in the form of gender quota. The policy has the potential to strengthen women’s political participation and representation. Nevertheless, empirically, this has not always been the case. As one would expect, there …

Can Beach Cleans Do More Than Clean-Up Litter? Comparing Beach Cleans To Other Coastal Activities, Kayleigh J. Wyles, Sabine Pahl, Richard C. Thompson, M Holland

School of Psychology

No abstract provided.

Assisted Tree Migration In North America: Policy Legacies, Enhanced Forest Policy Integration, And Climate Change Adaptation, Adam Wellstead, Michael Howlett

Department of Social Sciences Publications

The weight of much expert forest management opinion is that issues such as climate change can be effectively addressed only if forest policy-making moves from a purely sectoral focus and undergoes a shift to a more integrated multi-issue, multi-sector policy-making process. This is because credible adaptation policies in the sector require greatly enhanced multi-sectoral policy integration if they are to succeed. But this requirement may be beyond the capacity of many countries to deliver. This article explores the integration challenges faced by forest policy-making in Canada and the United States and uses the case of Assisted Tree Migration (ATM) to …

The Grizzly Details, Fall 2016, Staff Assembly

Staff Assembly Newsletter

No abstract provided.

Weights And Balances: Integrating Models For Prevention And Response To Southern California Offshore Oil Spills, Carmen Watts Clayton, Amoret Bunn

STAR Program Research Presentations

Licensing offshore oil and gas reserves in the United States waters are overseen by the U.S. Department of the Interior’s Bureau of Safety and Enforcement (BSEE). The licensing application includes planning for any worst-case oil spill scenario between BSEE and the applicant based on lessons learned from historic offshore spills such as the Deepwater Horizon (2010), Exxon Valdez (1989), and the Union Oil Platform Blowout (1969). The process for planning to respond to oil spills involves coordination with multiple agencies, trustees, and stakeholders to ensure that oil spill responses consider multiple factors, including ecologically sensitive species, commercial transportation and fisheries, …

Soil Moisture On Soledad Ridge In Santa Rosa Island, Channel Islands National Park, Carrie Fong, Kathryn Mceachern, Ken Niessen

STAR Program Research Presentations

Santa Rosa Island is one of the Channel Islands off the coast of southern California. Before the island was heavily grazed, Santa Rosa Island is thought to have had large stands of island oak trees, Quercus tomentella, that provided a critical source of water for the ecosystem by creating a “cloud forest”. Wind-borne fog collects on the leaves, branches, and twigs of the island oaks and other native shrubs. Once the water condenses it drips, falls, and soaks into the soil. Introducing cattle and especially sheep to the island has damaged the ecosystem and nearly decimated Santa Rosa Island …

Studying The Effects Of Serpentine Soil On Adapted And Non-Adapted Species Using Arduino Technology, Kiana Saniee, Edward Himelblau, Brian Paavo

STAR Program Research Presentations

Abstract: Serpentine soils are formed from ultramafic rocks and are represent an extreme environment for plants. Serpentine soils are unique in that they carry high concentrations of heavy metals, are nutrient deficient, particularly in calcium, and have poor water retention capabilities. Although these soils constitute harsh conditions for plant growth, there are a number of species that are adapted and even endemic to serpentine soil. Water retention by commercial potting mix was compared with serpentine soil. Also, serpentine adapted and non-adapted species were grown in both soil treatments and physiological data were collected. We used the Arduino electronic platform to …

Making Research Matter: Democratizing Science And Other Lofty Goals, Richelle Winkler

Distinguished Lecture Series

Dr. Richelle Winkler gave the inaugural Michigan Tech Research Forum Distinguished Lecture in October 2016. She discussed Making Research Matter: Democratizing Science and Other Lofty Goals.

Professor Hugh Gorman nominated Winkler, an associate professor of sociology and demography, for “community engaged scholarship" that extends across the Michigan Tech campus.

Examples of Winkler's projects include examining the feasibility—social and technical—of using mine water for geothermal heating systems in Calumet and examining the social, economic, and technical aspects of improving recycling in Houghton County. Both projects involve students and community members, and both have a real impact in the communities.

Winkler …

Exploring Activism: A Journey With Women-Identified Student Activists At Laurier Brantford And How Activism Can Have A Positive Impact On Campus Culture, Sarah Cifani

Social Justice and Community Engagement

Feminist student activism at Wilfrid Laurier University Brantford campus has changed and progressed over the last decade. Currently, woman-identified feminist students are actively fighting to end rape culture on campus by educating students on feminism, consent, and the negative impacts of a rape culture. This research study highlights the challenges and barriers faced by activists as they work within an institution that presents patriarchal, heternormative, and racist ideals. This research study utilized qualitative research methods to interview seven woman-identified feminist student activists from Laurier Brantford, consisting of current, graduating and graduated students. Each participant was interviewed about their experience as …

The Biopolitical Critique Of The Notion Of Being Human And An Affirmation Of Lives, Ramanpreet Bahra

Sociology Major Research Papers

This major research paper (MRP) interrogates the discourse of ableism and disableism and its impact on disabled and fat bodies. The general theme of this MRP is the division of life through the dichotomy of human and non-human, and nondisabled and disabled. Humanism, overall is the benchmark from which other life forms, the animate and non-animate, are disaffirmed and looked at as being a deficit. With the use of DisCrit and Fat studies, in particular, an autoethnographic methodology will be used to situate how the writer embodies racism, ableism and sizeism and the ways theory is carried through the body. …

A Nurse's Face: The Burqa In The Hospital, Lucas Newbill

North Carolina Central Law Review

No abstract provided.

College Of Science And Mathematics Newsletter, Fall 2016, College Of Science And Mathematics, Wright State University

College of Science and Mathematics Newsletters

This 6 page newsletter discusses various happenings within the College of Science and Mathematics. It begins with a letter from the dean, and continues on with news, events, alumni news, and other community news.

New Faculty Guide To Competing For Research Funding, Mike Cronan, Lucy Deckard

Office of Research and Sponsored Programs Reports and Publications

Guide for Morehead State University faculty on finding and writing research grants printed in October of 2016.

Healthnet News V.31:No.3 Fall 2016, Wendy Urciuoli

Articles - Patient Care

Linking Connecticut Patients and Families to Reliable Health Information

A Study Of Defensive Mechanisms Employed By Two Species Of Nudibranchs Using Toxicity And Unpalatability Analyses, Sean Youn

Independent Study Project (ISP) Collection

Nudibranchs are marine invertebrates that have developed an intriguing defense mechanism, including warning coloration and the use of chemicals accumulated through their sponge diet. The goal of this study was to determine whether the strength of chemical defenses differs between dietary and accumulated secondary metabolites for two species: Glossodoris vespa and Ceratosoma brevicaudatum. First, NMR spectroscopy was used to not only identify specific compounds in the mantle (outer covering) and the viscera (gut) but also to analyze the possibility of nudibranch species transporting more toxic compounds for defensive purposes. Next, toxicity (brine shrimp) and palatability (Palaemon shrimp) assays were used …

Breast Is Best: Determinants Of Breastfeeding In Bali, Leah Hardenbergh

Independent Study Project (ISP) Collection

Breastfeeding greatly benefits the health of newborns, providing them with needed antibodies and protection from numerous diseases, including some of the leading causes of infant mortality. This paper explores breastfeeding practices in Bali, and the wide array of factors that have led to these practices. After discussing how breastfeeding fits into the larger context of maternal and newborn health, I explain factors in Bali that affect a woman’s decision to breastfeed and experience while breastfeeding. Determinants include those related to health, financial position, and social status. I explore the history of formula companies and formula as an alternative to breastmilk, …

Actually, Let’S Not Talk About Sex: The Value-Laden Sex Education Received By China’S Young Women, Allyson Tsu

Independent Study Project (ISP) Collection

No abstract provided.

Editorial: Food Legume Diversity And Legume Research Policies, Matthew W. Blair, Jing Wu, Shumin Wang

Agricultural and Environmental Sciences Faculty Research

No abstract provided.

Evaluation Of Common Bean (Phaseolus Vulgaris L.) Genotypes For Drought Stress Adaptation In Ethiopia, Kwabena Darkwa, Daniel Ambachew, Hussein Mohammed, Asrat Asfaw, Matthew W. Blair

Agricultural and Environmental Sciences Faculty Research

Drought stress linked with climate change is one of the major constraints faced by common bean farmers in Africa and elsewhere. Mitigating this constraint requires the selection of resilient varieties that withstand drought threats to common bean production. This study assessed the drought response of 64 small red-seeded genotypes of common bean grown in a lattice design replicated twice under contrasting moisture regimes, terminal drought stress and non-stress, in Ethiopia during the dry season from November 2014 to March 2015. Multiple plant traits associated with drought were assessed for their contribution to drought adaptation of the genotypes. Drought stress determined …

Qtl And Candidate Genes Associated With Common Bacterial Blight Resistance In The Common Bean Cultivar Longyundou 5 From China, Jifeng Zhu, Jing Wu, Lanfen Wang, Matthew W. Blair, Zhendong Zhu, Shumin Wang

Agricultural and Environmental Sciences Faculty Research

Common bacterial blight (CBB), caused by Xanthomonas axonopodis pv. phaseoli and Xanthomonas fuscans subsp. fuscans (Xff), is a worldwide disease of common bean (Phaseolus vulgaris L.). Longyundou 5, a Chinese cultivar in the Mesoamerican gene pool of common bean, displays resistance to the Xff strain XSC3-1. To identify the genetic mechanisms behind this resistance, we crossed Long 5 with a susceptible genotype to develop a mapping population of F2 plants. Plant resistance to CBB was identified at 14 and 21 days after inoculation with Xff strain XSC3-1. A major QTL at 14 and 21 days after inoculation …

Climate Change And The Delta, San Francisco Estuary And Watershed Science, Michael D. Dettinger, Jamie Anderson, Michael L. Anderson, Larry R. Brown, Daniel R. Cayan, Edwin P. Maurer

Civil, Environmental and Sustainable Engineering

Anthropogenic climate change amounts to a rapidly approaching, “new” stressor in the Sacramento–San Joaquin Delta system. In response to California’s extreme natural hydroclimatic variability, complex water-management systems have been developed, even as the Delta’s natural ecosystems have been largely devastated. Climate change is projected to challenge these management and ecological systems in different ways that are characterized by different levels of uncertainty. For example, there is high certainty that climate will warm by about 2°C more (than late-20th-century averages) by mid-century and about 4°C by end of century, if greenhouse-gas emissions continue their current rates of acceleration. Future precipitation changes …

Unraveled Fall 2016, Southern Adventist University

Unraveled - School of Education and Psychology Newsletter

The Fall 2016 issue of Unraveled features articles on the outdoor education masters program, the Psych Lab, a pictorial directory of the December 2016 education and psychology graduates, and spotlights on new faculty and alumni.