Digital Commons Network^™

Stepwise Generation Of Retinal Progenitor Cells From Human Embryonic Stem Cells On Defined Matrix Coatings, Jessica Patterson Antipenko

All ETDs from UAB

Membrane proteins imperative for cell signal transduction, G-protein coupled receptors (GPCRs) are critical for drug discovery. Unfortunately, sufficient amounts of quantifiable protein cannot be produced using existing expression systems. Nature has an ideal solution—rhodopsin; the GPCR rhodopsin is efficiently and abundantly expressed in rod outer segments (ROS) of photoreceptor cells. As part of this study, human embryonic stem cells (hESC) were cultured on extracellular matrix (ECM) derived substrates and differentiated towards a photoreceptor lineage using conventional basic fibroblast growth factor (bFGF) and novel NM23 growth factor methods. NM23 is the natural ligand of MUC1*, which is surface accessible on stem …

Pattern Formation And Semilinear Evolution Equations In Function Spaces, Kwadwo Antwi-Fordjour

All ETDs from UAB

predictors, and find that under the test of group differences, MacKinnon and White’s HC2

Low Power Oscillator Based Sensor Signal Monitoring System, A K M Arifuzzman

All ETDs from UAB

With the advances in the integrated circuit technologies, various types of micro- and nano-sensors are increasingly being utilized in different fields such as medical monitoring, wireless health monitoring, structural health monitoring, where low power consumption, small dimensions, multi-signal sensing capabilities and wireless telemetry are required. Various types of bio-electrical signals are used in the medical sensor systems for diagnostics as well as therapeutic interventions. Usually, bio-signals have the common features of low frequency, and low amplitude level. In this work, a low current sensor signal monitoring system has been proposed and developed, which possesses several merits in terms of high …

Assemblage Structure, Production, And Food Web Dynamics Of Macroinvertebrates In Tropical Island Headwater Streams, Keysa G. Rosas-Rodriguez

College of Graduate Studies: Theses & Dissertations

Variation in long-term temperature and precipitation patterns will likely influence the decomposition and export of benthic organic matter and influence aquatic macroinvertebrate consumer communities. Tropical systems are relatively understudied; therefore basal information is urgently needed. As part of an ongoing long-term study, we monitored macroinvertebrates in two shrimp-dominated and fishless headwater streams within the Luquillo Experimental Forest in Puerto Rico from 2009-2010. We combined growth rates with yearly biomass data to calculate secondary production and examined gut contents to develop quantitative food webs. Macroinvertebrate assemblages were dominated by a few insect taxa, with similar biotic composition across streams and habitats, …

Court-Appointed Special Advocates In The Rural South: A Fidelity Assessment, Shanna N. Felix

College of Graduate Studies: Theses & Dissertations

Children in the court system who are abused or neglected are mandated by the federal Child Abuse Prevention and Treatment Act (CAPTA) to have special legal representation in the form of a Guardian ad Litem (GAL). A GAL can be a staff attorney or he or she can be a volunteer layperson (known as a Court-Appointed Special Advocate, or CASA) who has undergone the GAL training. In some states, the CASA volunteer can be a substitute for the GAL, while in other states (like Georgia) the CASA is appointed by the judge as a complement to the staff attorney. To …

A Phenomenological Study Of Teachers' Perceptions Of Kindergarten Retention: Are Standards To Be Blamed?, Ginger Delaigle

College of Graduate Studies: Theses & Dissertations

Currently there are a number of Kindergarten students who are being retained for not mastering Common Core State Standards. One of the methods that teachers can use to support Kindergarten students in achieving these standards are Developmentally Appropriate Practices. The exploration of the perceptions of teachers who have experienced the phenomenon of retaining Kindergarten students served as the goal for this qualitative, phenomenological study. The results provided data for examination of the perceptions the teachers had with retaining Kindergarten students and their perceptions of the developmental appropriateness of the Common Core State Standards. Four Kindergarten teachers participated in three interviews …

Domestic Violence In Lac Su’S I Love Yous Are For White People: A Sociological Criticism Approach, Quan-Manh Ha

Asian American Literature: Discourses & Pedagogies

This article employs sociological criticism to examine domestic violence, parenting, and communication behavior in Lac Su’s Vietnamese American memoir. The book debunks the seemingly positive myth of Asian Americans as a model minority, substantiates certain negative stereotypes of Asian men, and challenges some of the classic Asian values that apparently have shaped the Asian American identity. I argue that Su’s memoir is a critique of structural inequalities, urban poverty, unemployment, inaccessibility to a support network, and the intersection between class, gender, and race in the contexts of war and its aftermath.

Crystal Structure Of (E)-2-[(2- Bromo-3-Pyridyl)Methylidene]-6-Methoxy-3,4-Dihydronaphthalen-1-One And 3-[(E)-(6- Methoxy-3,4-Dihydronaphth-2-Oylidene)Methyl]-1h-Pyridin-2-One, Sarah K. Zingales, Morgan E. Moore, Andrew D. Goetz, Clifford W. Padgett

Chemistry: Faculty Publications (1990-2023)

The title compounds C17H14BrNO2, (I), and C17H15NO3, (II), were obtained from the reaction of 6-meth­oxy-3,4-di­hydro-2H-naphthalen-1-one and 2-bromo­nicotinaldehyde in ethanol. Compound (I) was the expected product and compound (II) was the oxidation product from air exposure. In the crystal structure of compound (I), there are no short contacts or hydrogen bonds. The structure does display [pi]-[pi] inter­actions between adjacent benzene rings and adjacent pyridyl rings. Compound (II) contains two independent mol­ecules, A and B, in the asymmetric unit; both are non-planar, the dihedral angles between the meth­oxy­benzene and 1H-pyridin-2-one mean planes being 35.07 (9)° in A and 35.28 (9)°in B. In …

Replication Datasets For Consequences Of Secondary Calibrations On Divergence Time Estimates, John J. Schenk

Biology: Faculty Datasets (2016-2023)

No abstract provided.

2016 Spring Commencement, Georgia Southern University

Commencement Programs

No abstract provided.

Common Data Set, 2015-2016, Planning, Research, And Policy Analysis

Common Data Set (2001-present)

Common Data Set 2015-2016 for Illinois State University

Modeling Of Rheological Properties For Entangled Polymer Systems, Nilanjana Banerjee

Doctoral Dissertations

"The study of entangled polymer rheology both in the field of medicine and polymer processing has their major importance. Mechanical properties of biomolecules are studied in order to better understand cellular behavior. Similarly, industrial processing of polymers needs thorough understanding of rheology so as to improve process techniques. Work in this dissertation has been organized into three major sections. Firstly, numerical/analytical models are reviewed for describing rheological properties and mechanical behaviors of cytoskeleton. The cytoskeleton models are classified into categories according to the length scales of the phenomena of interest. The main principles and characteristics of each model are summarized …

Continuous Flow Reactor For Carbonic Acid Hydrolysis/Pretreatment Of Microalgal Biomass To Produce Bioethanol, Nicholas Dudenhoeffer

Doctoral Dissertations

"In order to maximize bioethanol production an efficient pretreatment method for the hydrolysis of polysaccharides to fermentable sugars is necessary. Commonly used pretreatment methods are the slow enzymatic hydrolysis and the corrosive mineral acid hydrolysis process that requires a post-treatment neutralization step and generates waste stream. We investigated the high temperature water with carbonic acid catalyst as an alternative method. Carbonic acid generated from dissolved CO₂ is inexpensive and environmentally benign, and easily removed by decompression. A high pressure continuous flow reactor that can continuously process the wet biomass stream and perform the carbonic acid hydrolysis in-situ using the …

Contribution Of New Thiol Antioxidant In The Treatment Of Acetaminophen Toxicity, Ahdab Naeem Khayyat

Doctoral Dissertations

"Acetaminophen (N-acetyl-p-aminophenol, APAP) is one of the most widely used over-the-counter antipyretic analgesic medications. It is safe at therapeutic doses, but an overdose can result in severe hepato-nephrotoxicity, a leading cause of drug-induced acute liver failure in the U.S. Although a few different mechanisms have been proposed for APAP-induced toxicity, a significant amount of evidence has pointed to the potential involvement of oxidative stress in acetaminophen toxicity. Depletion of glutathione (GSH) is one of the initiating steps in APAP-induced toxicity; therefore, one strategy for restricting organ damage is to restore GSH levels by using GSH prodrugs like N-acetylcysteine (NAC). Although …

Clustering: Methodology, Hybrid Systems, Visualization, Validation And Implementation, Dao Minh Lam

Doctoral Dissertations

"Unsupervised learning is one of the most important steps of machine learning applications. Besides its ability to obtain the insight of the data distribution, unsupervised learning is used as a preprocessing step for other machine learning algorithm. This dissertation investigates the application of unsupervised learning into various types of data for many machine learning tasks such as clustering, regression and classification. The dissertation is organized into three papers. In the first paper, unsupervised learning is applied to mixed categorical and numerical feature data type to transform the data objects from the mixed type feature domain into a new sparser numerical …

Synthesis And Functionalization Of A Triaryldiamine-Base Photoconductive/Photorefractive Composite, And Its Application To Aberrated Image Restoration, Yichen Liang

Doctoral Dissertations

"Organic photorefractive (PR) composites have recently emerged as an important class of materials for applications including high-density data storage, optical communication, and biomedical imaging. In an effort to further improve their performance, this study focused on the utilization of functionalized semiconductor nanocrystals to photosensitize triaryamine (TPD)-based PR composites, as well as the application of TPD-based PR composites in the restoration of aberrated optical information. A novel approach to functionalize CdSe quantum dot (QCdSe) was firstly introduced where the sulfonated triarydiamine (STPD) was used as charge-transporting ligand to passivate QCdSe. TPD-based photoconductive and PR composites were photosensitized with the STPD-passivated QCdSe …

Existence And Classification Of Nonoscillatory Solutions Of Two Dimensional Time Scale Systems, Özkan Özturk

Doctoral Dissertations

"During the past years, there has been an increasing interest in studying oscillation and nonoscillation criteria for dynamic equations and systems on time scales that harmonize the oscillation and nonoscillation theory for the continuous and discrete cases in order to combine them in one comprehensive theory and eliminate obscurity from both.

We not only classify nonoscillatory solutions of dynamic equations and systems on time scales but also guarantee the (non)existence of such solutions by using the Knaster fixed point theorem, Schauder - Tychonoff fixed point theorem, and Schauder fixed point theorem. The approach is based on the sign of nonoscillatory …

Multi-Level Evolutionary Algorithms Resource Allocation Utilizing Model-Based Systems Engineering, Bhanuchander Reddy Poreddy

Doctoral Dissertations

"This research presents an innovative approach to solve the resource allocation problems using Multi-level Evolutionary Algorithms. Evolutionary Algorithms are used to solve resource allocation problems in different domains and their results are then incorporated into a higher level system solution using another Evolutionary Algorithm to solve base camp planning problems currently faced by the U.S. Department of Defense.

Two models are introduced to solve two domain specific models: a logistics model and a power model. The logistic model evaluates routes for logistics vehicles on a daily basis with a goal of reducing fuel usage by delivery trucks. The evaluation includes …

Spectroscopic And Spectro-Astrometric Analysis Of T Tauri Stars, Logan Ryan Brown

Doctoral Dissertations

"To understand our own solar origins, we must investigate the composition of the protoplanetary disk from which the solar system formed. To infer this, we study analogs to the early solar system called T Tauri stars. These objects are low-mass, pre-main sequence stars surrounded by circumstellar disks of material from which planets are believed to form. We present high-resolution, near-infrared spectroscopic data for the T Tauri stars DR Tau and AA Tau using NIRSPEC at the Keck II telescope. For DR Tau, a spectro-astrometric analysis was performed, obtaining sub-seeing spatial information on water emission. Alongside a disk model, we constrained …

Polyacrylamide And Its Derivatives For Oil Recovery, Zun Chen

Doctoral Dissertations

"Polyacrylamide is an umbrella term used to describe the homo-polymer of acrylamide and the copolymer of acrylamide with a small amount of other monomers. Owing to their superior property on increasing viscosity and gelling ability in the presence of crosslinkers, polyacrylamides has become the primarily selection for polymer flooding and gel treatment agent in enhanced oil recovery. Recent developments, performance, applications and limitations of polyacrylamides and its derivatives, including copolymers and hydrogels for enhancing oil recovery are reviewed.

A water-free suspension system was developed to synthesize PAMs and PAMs-microgel. Products are dry particle powder and ready to disperse in water. …

Palynological Studies Of Holocene Lake Sediments In The Missouri Ozarks, Robert D. Haselwander

Doctoral Dissertations

"Five small lakes in southeast Missouri (Frisco, Pine Forest, and Bray Area lakes [Phelps County], and Cypress and Blue ponds [Bollinger County]) were cored for paleolimnological studies. Cores were evaluated for their sedimentology, palynology, and geochemistry. In two of these lakes (Bray Area and Pine Forest lakes) the planktonic algae were also studied in the water column, along with ecological parameters. Algae in the sediments were compared to algae in the water to understand the resistance of different species to decay, and a suggested methodology for this work is described. Reconstructions of the past environments around each lake were created …

Analysis And Mitigation Of Wellbore Breakout And Fracturing, Reza Rahimi

Doctoral Dissertations

"Mechanical wellbore integrity problems while drilling are mainly due to wellbore shear failure or tensile failure. To ensure wellbore integrity, breakout and fracture geomechanical analysis is conducted to estimate minimum and maximum drilling fluid densities. Currently, there is no agreement as to which rock failure criterion to use for estimating breakout or fracture criteria to use for analyzing drilling induced fractures. However, when wellbore integrity issues arise while drilling, mitigation strategies can be applied to rectify these problems.

This dissertation analyzes criteria for wellbore breakout and fracturing. Also, mitigation strategies for breakout and fracturing while drilling were experimentally investigated. Thirteen …

Transient Cfd Simulations Of Pumping And Mixing Using Electromagnetic, Fangping Yuan

Doctoral Dissertations

"In this dissertation, two dimensional and three dimensional, transient CFD simulations are conducted to investigate the active pumping and mixing in microfluidics driven by Electromagnetic/Lorentz force. Shallow disk/ring cylindrical microfluidic cell and shallow cuboid microfluidic cell with electrodes deposited on the bottom surface are modelled for mixing and pumping purposes respectively. By applying voltage across specific pair of electrodes, an ionic current is established in the weak conductive liquid present in the cell. The current interacts with an externally applied magnetic field generating a Lorentz force that causes fluid motion in the cell. Velocity vectors, electric potential distributions and ionic …

Nanostructured Materials Prepared By Atomic Layer Deposition For Catalysis And Lithium-Ion Battery Applications, Rajankumar Patel

Doctoral Dissertations

"Atomic/molecular layer deposition (ALD/MLD) has emerged as an important technique for depositing thin films in both scientific research and industrial applications. In this dissertation, ALD/MLD was used to create novel nanostructures for two different applications, catalysis and lithium-ion batteries.

MLD was used to prepare ultra-thin dense hybrid organic/inorganic polymer films. Oxidizing the hybrid films removed the organic components and produced the desired nanoporous films. Both porous alumina and titania films can be prepared by such a way. A novel nanostructured catalyst (Pt/SiO₂) with an ultra-thin porous alumina shell obtained from the thermal decomposition of an aluminium alkoxide film …

Single Particle-Inductively Coupled Plasma-Mass Spectrometry Technology Development For Metallic Nanoparticle Characterization In Complex Matrices, Yongbo Dan

Doctoral Dissertations

"As the rapid growing of nanotechnology, the release of engineered nanoparticles (ENPs) into the environment is inevitable. After entering the real environment, ENPs tend to react with different components of the ecosystem (e.g. water, soil, air, plants) and make their characterization difficult. Analyzing ENPs in these complex matrices still remains as a grand challenge. ENPs characterization is normally the first step of risk assessment. Current analytical techniques have shown some limitations in revealing the unique characteristics of ENPs in complex matrices and reliable analytical techniques are in urgent need. Single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) is an emerging …

The Social Contagion Of Adolescent Depression: Applying A Differential Susceptibility Model, Win Guan

LSU Doctoral Dissertations

Recent research investigating social risk factors of depression has found evidence for a social contagion effect. The research comes from a surge in popularity of using social network analyses to examine the spread of various health outcomes such as obesity, smoking, substance use, and sleep. Although the finding of depressive contagion represents a significant contribution to the literature on the social etiology of depression, this is only the first step in providing meaningful research useful for the practical application of curbing the growing rates of depression especially among adolescents. Rather than simply acknowledging the existence of contagion effects, researchers must …

Coastal Flood Risk In A Changing Climate Along The Northern Gulf Of Mexico, Matthew Vernon Bilskie

LSU Doctoral Dissertations

Coastal regions around the world are experiencing increased vulnerability from natural and manmade disasters. It is anticipated that coastal flood risk will increase due to the effects of climate change, and sea level rise (SLR) in particular. A dynamic, physics-based, framework to compute coastal flood inundation maps under various climate change scenarios was developed. The novel modeling system includes not only SLR, but considers future projections of shoreline evolution and primary dune morphology, upland migration of intertidal marsh, and land use land cover change. A present day hurricane storm surge model was generated for the Mississippi, Alabama, and Florida panhandle …

Echo Phenomena In Populations Of Chemical Oscillators, Tianran Chen

Graduate Theses, Dissertations, and Problem Reports (ETD)

The emergence of collective behavior has been observed in all levels of biological systems, for example, the aggregation of slime mold, swarm motion of insects and the collective motion in schools of sh. Synchronization is one of the most important collective behaviors and can play a pivotal role in maintaining the normal function of a living system, such as pacemaker cells in the heart, circadian rhythms, and insulin release from pancreatic cells. Synchronization typically arises as a result of the interaction of large ensembles of oscillators. Studies of the Belousov-Zhabotinsky (BZ) chemical oscillators have shown a variety of collective dynamical …

Peg3 Functions As A Repressor For Its Downstream Genes, An Ye

LSU Doctoral Dissertations

Paternally expressed gene 3 (Peg3) is an imprinted gene that encodes a protein with twelve C2H2 zinc finger domains. Thus, PEG3 protein is predicted to serve as a transcription factor that may regulate other gene expression. Chromatin immunoprecipitation (ChIP) experiment revealed a list of genes that are bound by PEG3, supporting PEG3 is a DNA-binding protein. Genome wide expression analysis using wild type and Peg3 knockout mouse models further suggested that a large number of genes were up-regulated in Peg3 knockout model, including imprinted genes and some tissue-specific genes, suggesting that PEG3 may mainly function as a repressor for its …

The Instruction Of Eros: A Content Analysis Of Sex Education Texts, Nicholas Ensley Mitchell

LSU Doctoral Dissertations

This study is a directed content analysis that employs a memetic framework done in order to determine what discourses are evident in, how diversity is represented in, and how intersectionality is represented in two sex education texts, and to compare the relevant frequencies. Theories from the dominant schools of thought concerning sex education and sexuality are enumerated, compared, and contrasted. A historiography of sex education in the United States is provided to establish context for the sampled texts. A explanation of the content analysis process in general and the methodology specifically used in this study is discussed followed by the …