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Physical And Electrochemical Area Determination Of Electrodeposited Ni, Co, And Nico Thin Films, Matthew Gira, Kevin Tkacz, Jennifer R. Hampton

Faculty Publications

The surface area of electrodeposited thin films of Ni, Co, and NiCo was evaluated using electrochemical double-layer capacitance, electrochemical area measurements using the [Ru(NH₃)₆]³⁺/[Ru(NH₃)₆]²⁺ redox couple, and topographic atomic force microscopy (AFM) imaging. These three methods were compared to each other for each composition separately and for the entire set of samples regardless of composition. Double-layer capacitance measurements were found to be positively correlated to the roughness factors determined by AFM topography. Electrochemical area measurements were found to be less correlated with measured roughness factors as well as applicable …

Association Of Caregiver Quality Of Care With Neurocognitive Outcomes In Hiv-Affected Children Aged 2–5 Years In Uganda, Judith Bass, Noeline Nakasujja, Itziar Familiar-Lopez, Alla Sikorskii, Sarah Murray, Robert Opoka, Jura Augustinavicius, Michael Boivin

Paediatrics and Child Health, East Africa

Abstract: Children affected by HIV are at increased risk of developmental and neuropsychological disturbances due to direct effects of HIV on the brain and direct effects associated with living in poverty. Caregivers can play an important role, through quality caregiving, in mitigating the negative effect of these stressors. This study used baseline data from an ongoing caregiver training intervention trial to evaluate the association between quality of caregiver-child interactions and neurocognitive outcomes in rural HIV-infected and HIV-exposed but uninfected children in Uganda. We also assessed the extent to which caregiver distress moderated this relationship. Data on 329 caregiver-child dyads were …

Variations In Adolescent Disclosure Among Latinas, Eve Veliz-Moran

Journal of Latino/Latin American Studies (JOLLAS)

This study examines attitudes toward adolescent disclosure among a diverse sample of Latina adolescents. Using ecological and acculturation frameworks, this qualitative, exploratory study analyzes responses from 18 Latina adolescents to open-ended, semi-structured questions from the National Study of Youth and Religion on family relationships, morality, and religion, to explore disclosure attitudes. Results suggest high disclosure to mothers, particularly by Latinas from low-income and religiously congruent families. Fathers’ long work hours and singular religiosity thwart disclosure to them, and family structure, migration, and nativity influence whether adolescent Latinas disclose information to parents. Latino cultural values of respeto and marianismo did not …

To Live, Wendy M. Payne

BYU Studies

“To live is so startling it leaves little time for anything else.”

Emily Dickinson

A Faded Legacy: Amy Brown Lyman And Mormon Women's Activism, 1872-1959, Lisa Olsen Tait

BYU Studies

Dave Hall. A Faded Legacy: Amy Brown Lyman and Mormon Women's Activism, 1872-1959.

Salt Lake City: University of Utah, 2015.

A Branch Point Of Streptomyces Sulfur Amino Acid Metabolism Controls The Production Of Albomycin, Aditya Kulkarni, Yu Zeng, Wei Zhou, Steven Van Lanen, Weiwen Zhang, Shawn Chen

Pharmaceutical Sciences Faculty Publications

Albomycin (ABM), also known as grisein, is a sulfur-containing metabolite produced by Streptomyces griseus ATCC 700974. Genes predicted to be involved in the biosynthesis of ABM and ABM-like molecules are found in the genomes of other actinomycetes. ABM has potent antibacterial activity, and as a result, many attempts have been made to develop ABM into a drug since the last century. Although the productivity of S. griseus can be increased with random mutagenesis methods, understanding of Streptomyces sulfur amino acid (SAA) metabolism, which supplies a precursor for ABM biosynthesis, could lead to improved and stable production. We previously characterized the …

Abortion And The Right To Not Be Pregnant, James E. Mahon

Publications and Research

In this paper I defend Judith Jarvis Thomson's 'Good Samaritan Argument' (otherwise known as the 'feminist argument') for the permissibility of abortion, first advanced in her important, ground-breaking article 'A Defense of Abortion' (1971), against objections from Joseph Mahon (1979, 1984). I also highlight two problems with Thomson's argument as presented, and offer remedies for both of these problems. The article begins with a short history of the importance of the article to the development of practical ethics. Not alone did this article put the topic of the abortion on the philosophical map, but it made 'practical ethics' in the …

Seedling Survival Responses To Conspecific Density, Soil Nutrients, And Irradiance Vary With Age In A Tropical Forest, Sydne Record, Richard K. Kobe, Corine F. Vriesendorp, Andrew O. Finley

Biology Faculty Research and Scholarship

Predicting long-term trends in forest growth requires accurate characterisation of how the relationship between forest productivity and climatic stress varies across climatic regimes. Using a network of over two million tree-ring observations spanning North America and a space-for-time substitution methodology, we forecast climate impacts on future forest growth. We explored differing scenarios of increased water-use efficiency (WUE) due to CO2-fertilisation, which we simulated as increased effective precipitation. In our forecasts: (1) climate change negatively impacted forest growth rates in the interior west and positively impacted forest growth along the western, southeastern and northeastern coasts; (2) shifting climate sensitivities offset positive …

O-Alkylhydroxylamines As Rationally-Designed Mechanism-Based Inhibitors Of Indoleamine 2,3-Dioxygenase-1, William Paul Malachowski, Maria Winters, James B. Duhadaway, Ariel Lewis-Ballester, Shorouk Badir, Maisha Rahman, Eesha Sheikh, Judith M. Lalonde, Syun-Ru Yeh, George C. Prendergast, Alexander J. Muller

Chemistry Faculty Research and Scholarship

Indoleamine 2,3-dioxygenase-1 (IDO1) is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. Recently important advances have been made in understanding IDO1’s catalytic mechanism. Although much remains to be discovered, there is strong evidence that the mechanism proceeds through a heme-iron bound alkylperoxy transition or intermediate state. Accordingly, we explored stable structural mimics of the alkylperoxy species and provide evidence that such structures do mimic the alkylperoxy transition or intermediate state. We discovered that O-benzylhydroxylamine, a commercially available compound, is a potent sub-micromolar inhibitor of IDO1. Structure-activity studies of …

Cortical And Psychological Mechanisms Of Visceral Pain, Kelly L. Polnaszek

Master's Theses

Objective: Dysmenorrhea is an incapacitating type of visceral pain that affects numerous menstruating women and is defined by painful menstrual cramps and often occurs in the absence of pelvic pathology. Women with dysmenorrhea have reported higher sensitivity to experimental pain, and vulnerability to pain sensitivity may be a primary risk factor for developing chronic pelvic pain for women with dysmenorrhea. Cross-organ sensitization (COS), or the theory that uterine inflammation during menstruation can contribute to chronic pelvic pain by generating neurogenic inflammation in other organs, may be a primary mechanism associated with pelvic pain in women with dysmenorrhea. Dysmenorrhea sufferers with …

Dickkopf-Related Protein 1 (Dkk1) Regulates The Accumulation And Function Of Myeloid Derived Suppressor Cells In Cancer, Lucia D'Amico, Sahil Mahajan, Aude-Helene Capietto, Zhengfeng Yang, Ali Zamani, Biancamaria Ricci, David B. Bumpass, Melissa Meyer, Xinming Su, Andrea Wang-Gillam, Katherine Weilbaecher, Sheila A. Stewart, David G. Denardo, Roberta Faccio

Open Access Publications

No abstract provided.

Local Admixture Of Amplified And Diversified Secreted Pathogenesis Determinants Shapes Mosaic Toxoplasma Gondii Genomes, Asis Khan, Michael S. Behnke, L David Sibley, Et Al

Open Access Publications

No abstract provided.

Antibody Response To The Hypervariable Region-1 Interferes With Broadly Neutralizing Antibodies To Hepatitis C Virus, Zhen-Yong Keck, Christine Girard-Blanc, Wenyan Wang, Patrick Lau, Adam Zuiani, Felix A. Rey, Thomas Krey, Michael S. Diamond, Steven K. H. Foung

Open Access Publications

No abstract provided.

Il-1-Induced Bhlhe40 Identifies Pathogenic T Helper Cells In A Model Of Autoimmune Neuroinflammation, Chih-Chung Lin, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Nicholas N. Jarjour, Chun Chou, Angela S. Archambault, Julia Sim, Bernd H. Zinselmeyer, Javier A. Carrero, Gregory F. Wu, Reshma Taneja, Maxim N. Artyomov, John H. Russell, Brian T. Edelson

Open Access Publications

No abstract provided.

Cancer Stem Cell Signaling During Repopulation In Head And Neck Cancer, George D. Wilson, Bryan J. Thibodeau, Laura E. Fortier, Barbara L. Pruetz, Sandra Galoforo, Brian Marples, Andrew M. Baschnagel, Jan Akervall, Jiayi Huang

Open Access Publications

No abstract provided.

Combinatorial Cis-Regulation In Saccharomyces Species, Aaron T. Spivak, Gary D. Stormo

Open Access Publications

No abstract provided.

Neuroimaging Evidence Of Deficient Axon Myelination In Wolfram Syndrome, Heather M. Lugar, Jonathan M. Koller, Jerrel Rutlin, Bess A. Marshall, Kohsuke Kanekura, Fumihiko Urano, Allison N. Bischoff, Joshua S. Shimony, Tamara Hershey, Washington University Wolfram Syndrome Research Study Group

Open Access Publications

No abstract provided.

Vortex Ring Behavior Provides The Epigenetic Blueprint For The Human Heart, Per M. Arvidsson, Sándor J. Kovács, Johannes Töger, Rasmus Borgquist, Einar Heiberg, Marcus Carlsson, Håkan Arheden

Open Access Publications

No abstract provided.

Aerobic Glycolysis In The Frontal Cortex Correlates With Memory Performance In Wild-Type Mice But Not The App/Ps1 Mouse Model Of Cerebral Amyloidosis, Richard A. Harris, Lauren Tindale, Asad Lone, Olivia Singh, Shannon L. Macauley, Molly Stanley, David M. Holtzman, Robert Bartha, Robert C. Cumming

Open Access Publications

No abstract provided.

Lithium Protects Against Anaesthesia Neurotoxicity In The Infant Primate Brain, Kevin K. Noguchi, Stephen A. Johnson, Lauren E. Kristich, Lauren D. Martin, Gregory A. Dissen, Emily A. Olsen, John W. Olney, Ansgar M. Brambrink

Open Access Publications

No abstract provided.

Using Propensity Score Methods To Assess Causal Effects Of Mothers' Dieting Behavior On Daughters' Early Dieting Behavior, Donna L. Coffman, Katherine N. Balantekin, Jennifer S. Savage

Open Access Publications

No abstract provided.

Exported Epoxide Hydrolases Modulate Erythrocyte Vasoactive Lipids During Plasmodium Falciparum Infection, Natalie J. Spillman, Varun K. Dalmia, Daniel E. Goldberg

Open Access Publications

No abstract provided.

Mutations In Mtr4 Structural Domains Reveal Their Important Role In Regulating Trnai(Met) Turnover In Saccharomyces Cerevisiae And Mtr4p Enzymatic Activities In Vitro, Yan Li, Joseph Burclaff, James T. Anderson

Open Access Publications

No abstract provided.

Analysis Of The Putative Role Of Cr1 In Alzheimer’S Disease: Genetic Association, Expression And Function, Maria I. Fonseca, Shuhui Chu, Aimee L. Pierce, William D. Brubaker, Richard E. Hauhart, Diego Mastroeni, Elizabeth V. Clarke, Joseph Rogers, John P. Atkinson, Andrea J. Tenner

Open Access Publications

No abstract provided.

Anthropometric Factors And Thyroid Cancer Risk By Histological Subtype: Pooled Analysis Of 22 Prospective Studies, Yikyung Park, Et Al

Open Access Publications

No abstract provided.

A Role For Genetic Susceptibility In Sporadic Focal Segmental Glomerulosclerosis, Haiyang Yu, Mykyta Artomov, Sebastian Brähler, M. Christine Stander, Ghaidan Shamsan, Matthew G. Sampson, J. Michael White, Matthias Kretzler, Jeffrey H. Miner, Sanjay Jain, Cheryl A. Winkler, Robi D. Mitra, Jeffrey B. Kopp, Mark J. Daly, Andrey S. Shaw

Open Access Publications

No abstract provided.

Genome-Wide Polygenic Scores For Age At Onset Of Alcohol Dependence And Association With Alcohol-Related Measures, Y-L Chou, P A F. Madden, L J. Bierut, A C. Heath, K K. Bucholz, A Agrawal

Open Access Publications

No abstract provided.

A Novel Secreted Protein, Myr1, Is Central To Toxoplasma’S Manipulation Of Host Cells, Magdalena Franco, Michael W. Panas, Nicole D. Marino, Mei-Chong Wendy Lee, Kerry R. Buchholz, Felice D. Kelly, Jeffrey J. Bednarski, Barry P. Sleckman, Nader Pourmand, John C. Boothroyd

Open Access Publications

No abstract provided.

Notch Signaling In Skeletal Progenitors Is Critical For Fracture Repair, Cuicui Wang, Jason A. Inzana, Anthony J. Mirando, Yinshi Ren, Zhaoyang Liu, Jie Shen, Regis J. O'Keefe, Hani A. Awad, Matthew J. Hilton

Open Access Publications

No abstract provided.

Sexual Dimorphism In Myocardial Acylcarnitine And Triglyceride Metabolism, Sriram Devanathan, Timothy D. Whitehead, Nicole Fettig, Robert J. Gropler, Samuel Nemanich, Kooresh I. Shoghi

Open Access Publications

No abstract provided.