Digital Commons Network^™

Pharmaceutical And Personal Care Products Concentrations In The Belgrade Lakes: A Possible Threat To Aquatic Ecosystems And Human Health, Serena Haver

Honors Theses

Pharmaceuticals and active ingredients from personal care products (PPCPs) include prescription and over-the-counter drugs, sunscreen, fragrances, and soaps. Recently researchers have detected PPCPs in surface waters, posing a threat to aquatic biota and human health. These compounds can enter the environment through dumping, direct excretion, or sewage effluent streams. We tested 14 water samples from East Pond, Great Pond, and Long Pond in Maine for the presence of 23 different PPCPs. Of those, we only detected significant levels of caffeine, 1,7-dimethylxanthine, and amphetamine all below 1µg/L. There were no significant differences between any of the three lakes for any of …

Assessing Lakesmart: The Development And Effectiveness Of A Lake Protection Program, Alexa A. E. Junker

Honors Theses

Maine’s nearly 6,000 lakes are a vital resource for the state, generating $6 billion in annual economic activity and sustaining 52,000 jobs. Over the course of the last several decades, this resource has increasingly been threatened by development and related problems, especially nutrient runoff. LakeSmart is a lake protection program designed to stem the flow of nutrient runoff by promoting and rewarding the use lake-friendly landscaping practices.

For this project, I traced the history of LakeSmart from its roots in the Maine Department of Environmental Protection and, through stakeholder interviews and surveys, chronicled its development into the flagship program of …

Are The Brain And The Mind One? Neuromarketing And How Consumers Make Decisions, Emily Glaenzer

Honors Theses

Neuromarketing utilizes brain-imaging technology, such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) machines, to understand consumers’ neurological responses to marketing stimuli. In this paper, I demonstrate how neuromarketing connects to the history of subliminal messaging and our current neuro-obsessed culture (neuroculture). These factors affect how critics view neuromarketing and the implications involved for the future of this study. I hypothesize that, when used correctly, neuromarketing can initiate a new section of the marketing world that will serve as a useful component to more traditional marketing practices. By taking away social bias and inaccurate answers present in market research, …

The Effect Of Temperature On The Supply And Demand For The American Lobster (Homarus Americanus) In The State Of Maine, Gaby E. Carpenter

Honors Theses

The Gulf of Maine (GOM) American lobster (Homarus americanus) stock accounts for 90% of the U.S. American lobster landings. This makes it an extremely valuable and important fishery on a national scale, but also to the state of Maine. In the past decade, the fishery has experienced rapid fluctuation in landings and price due to anthropogenic influences of the water temperature in the GOM. Given the economic importance of the fishery, it is important to understand the future impacts of climate change on the availability of lobster and economic consequences of these shifts. A bio-economic model is used in the …

Using Genetic Algorithms To Evolve Artificial Neural Networks, William T. Kearney

Honors Theses

This paper demonstrates that neuroevolution is an effective method to determine an optimal neural network topology. I provide an overview of the NeuroEvolution of Augmenting Topologies (NEAT) algorithm, and describe how unique characteristics of this algorithm solve various problem inherent to neuroevolution (namely the competing conventions problem and the challenges associated with protecting topological innovation). Parallelization is shown to greatly speed up efficiency, further reinforcing neuroevolution as a potential alternative to traditional backpropagation. I also demonstrate that appropriate parameter selection is critical in order to efficiently converge to an optimal topology. Lastly, I produce an example solution to a medical …

Development Of A Chemical Genetic Screen To Determine Synergistic Compounds With Laromustine In Treating Glioblastoma Multiforme Cultured Cells, Ryan Weeks

Honors Theses

Laromustine is a chemotherapeutic sulfonylhydrazine prodrug used in clinical trials to treat acute myeloid leukemia (AML) and glioblastoma multiforme (GBM). While treatment of AML with laromustine has more demonstrative clinical success, there are enough promising data against GBM to pursue additional pre-clinical and clinical experiments. To determine the synergistic effects caused by treating cultured GBM cells with laromustine and a library of FDA-approved compounds, a chemical genetic screen was developed. To optimize the screen, optimal cultured GBM cell seed density, growth period and maximum well capacity were determined. The treatment period for a lethal dose of laromustine in cultured GBM …

Experimental And Computational Study Of Methylphenylvinylidene And Its Rearrangements, Xi Yang

Honors Theses

In this study, the synthesis and properties were explored of the compound methylphenylvinylidene (MPV), a vinylidene carbene with methyl and phenyl groups as substituents. A phenanthrene-based precursor, 1-(1-phenylethylidene)-1a,9b-dihydro-1H-cyclopropa[l]phenanthrene, was synthesized in three steps and was subjected to photolysis in C₆D₆ at ambient temperature. During photolysis, the MPV carbene rearranged into 1-phenylpropyne via a 1,2-phenyl shift, instead of 1,2-methyl shift, confirmed by photolysis of ¹³C-labeled precursor. This experimental result is consistent with computational results using the CCSD(T)/cc-pVTZ//B3LYP/6-31+G* method. The calculations suggest that the 1,2-phenyl shift in singlet carbene requires 3.8 kcal/mol to overcome …

The Effect Of Cyanobacterium Gloeotrichia Echinulata In The Belgrade Lakes, Maine, Harriet T. Rothschild

Honors Theses

Gloeotrichia echinulata is a cyanobacteria species that has been increasingly forming blooms in oligotrophic lakes in the Northeastern United States. The Belgrade Lakes in central Maine have experienced increasing blooms over the past decades. Long Pond and Great Pond in the Belgrade Lakes region are popular locations for summer tourism and year-round residents. Research into G. echinulata is important to the Belgrade community because of potential effects to water quality, public health, and recreation. Studying G. echinulata bloom density throughout the summer and how it may affect the phosphorous cycle, the nitrogen cycle, and the plankton community will help scientists …

Spatial And Temporal Patterns In Irruptive Fringillid Movements, Paul J. Dougherty

Honors Theses

Historic Christmas Bird Count and eBird data indicate that during winter invasions, North American irruptive fringillid species occur in relatively even numbers across latitudes east of the Rocky Mountains. Most boreal breeding species show large southward invasions every other winter, with this pattern typically being strongest across the northern and mid United States. eBird data confirms that many northern fringillids irrupt synchronously, and both datasets also show positive correlations between the winter movements of southern breeding species in many areas. Winter abundance records show negative correlations between northern breeding species and southern breeding species in nearly all monitored areas of …

Environmental Contingency Of Seed-Fungi Interactions In Coexisting Invasive Purple Loosestrife And Native Cattail, Shayla R. Williams

Honors Theses

Purple loosestrife (Lythrum salicaria) is a highly invasive species able to quickly take over entire wetlands, especially after disturbances. Bountiful seed production and a persistent and prolific seed bank play a key role in loosestrife’s ability to invade. However, some competing native species, such as cattails (Typha spp.) have comparable seed production rates but less abundant seed banks, suggesting that there may be a difference in belowground seed survival. I investigated the abundance of loosestrife and cattail seeds in soils at roadside sites relative to above-ground stem densities. Given the importance of fungal pathogens to seed …

The Impact Of Endocrine-Disrupting Chemicals On Wildlife Conservation, Eda Reed

Honors Theses

Endocrine-disrupting chemicals (EDCs), such as those from plastics and pesticides, have been hypothesized to affect wildlife populations. According to the U.S. National Institute of Environmental Health Sciences, EDCs ‘are chemicals that may interfere with the body’s endocrine system and produce adverse developmental, reproductive, neurological, and immune effects in both humans and wildlife.’ A growing number of studies suggest wildlife are being exposed to EDCs, but how EDCs affect wildlife health and wildlife conservation is less well-understood. Through scientific literature analysis and a survey of wildlife conservationists and practitioners, this study aims to determine the current state of knowledge and data …

Ecological Predictors And Consequences Of Non-Native Earthworms In Kennebec County, Maine, Julia Rogers

Honors Theses

Non-native earthworms are found throughout much of the United States and southern Canada in areas that were glaciated during the most recent glaciation. These earthworms are changing nutrient cycling, modifying soil structure, and influencing diversity in forests throughout the Northern United States, and their invasion northward is facilitated by human activities. Although worms are present in compost piles and gardens of all Maine counties, there are no comprehensive studies of earthworms distributions in forested areas of Maine. I documented the presence and absence of earthworms in forested recreation areas in Kennebec County, Maine, and investigated ecological and landscape level variables …

Learning Analytics To Inform Teaching And Learning Approaches, Geraldine Gray, Colm Mcguinness, Philip Owende

Student Success

Learning analytics is an evolving discipline with capability for educational data analysis to enable better understanding of learning processes. This paper reports on learning analytics research at Institute of Technology Blanchardstown, Ireland, that indicated measureable factors can identify first year students at risk of failing based on data available prior to commencement of first year of study. The study was conducted over three years, 2010 to 2012, on a student population from a range of academic disciplines (n=1,207). Data was gathered from both student enrolment data maintained by college administration, and an online, self-reporting tool administered during induction sessions for …

Antibody Targeting Facilitates Effective Intratumoral Sirna Nanoparticle Delivery To Her2-Overexpressing Cancer Cells, Maria C. Palanca-Wessels, Garrett Booth, Anthony J. Convertine, Brittany B. Lundy, Geoffrey Y. Berguig, Michael F. Press, Patrick S. Stayton, Oliver W. Press

Materials Science and Engineering Faculty Research & Creative Works

The therapeutic potential of RNA interference (RNAi) has been limited by inefficient delivery of short interfering RNA (siRNA). Tumor-specific recognition can be effectively achieved by antibodies directed against highly expressed cancer cell surface receptors. We investigated the utility of linking an internalizing streptavidinconjugated HER2 antibody to an endosome-disruptive biotinylated polymeric nanocarrier to improve the functional cytoplasmic delivery of siRNA in breast and ovarian cancer cells in vitro and in an intraperitoneal ovarian cancer xenograft model in vivo, yielding an 80% reduction of target mRNA and protein levels with sustained repression for at least 96 hours. RNAi-mediated site specific cleavage …

Computational Assessment Of Neural Probe And Brain Tissue Interface Under Transient Motion, Michael Polanco, Sebastian Bawab, Hangsoon Yoon

Mechanical & Aerospace Engineering Faculty Publications

The functional longevity of a neural probe is dependent upon its ability to minimize injury risk during the insertion and recording period in vivo, which could be related to motion-related strain between the probe and surrounding tissue. A series of finite element analyses was conducted to study the extent of the strain induced within the brain in an area around a neural probe. This study focuses on the transient behavior of neural probe and brain tissue interface with a viscoelastic model. Different stages of the interface from initial insertion of neural probe to full bonding of the probe by astro-glial …

The Effect Of Trinexapac-Ethyl And Seeding Rate On Rice Milling Yields, İsmai̇l Sezer, Rasi̇m Ünan, Mevlüt Şahi̇n, Michael Orrin Way

Turkish Journal of Agriculture and Forestry

The effects of the plant growth regulator trinexapac-ethyl (TE), conjoined with different seeding rates of rice (Oryza sativa L.) milling yields, were evaluated in Turkey between 2009 and 2010. Two rice cultivars (Osmancık-97 and Karadeniz), three seeding rates (400, 500, and 600 seeds m-2), and four doses of TE (0, 100, 200, and 300 g ai ha-1) were compared. The experiments were designed in a randomized block in factorial ordering with 3 replicates. Quality factors including head, cargo, and total rice milling yields, 1000 grain weight, and lodging score were evaluated. Head rice milling yield was affected significantly; however, no …

Impact Of Long Term Soil Management Practices On The Fertility Andweed Flora Of An Almond Orchard, Giovanna Cucci, Giovanni Lacolla, Carmine Crecchio, Silvia Pascazio, Donato De Giorgio

Turkish Journal of Agriculture and Forestry

Soil management techniques can definitely influence soil quality, and particularly soil organic matter content, biological complexity, structure, and water holding capacity. Tillage may also have a negative effect by increasing erosion and organic matter oxidation processes, which have unavoidable repercussions on fertility. The objective of the current research was to test the effects of five different management techniques applied for 35 years on a rain-fed almond grove (Prunus amygdalus Batsch) in a hot-dry environment on some physicochemical, hydrological, and biological parameters. The following soil management techniques were compared: no-till (NT), with weed control by preemergence herbicides; NT, with chemical weed …

Yield And Fruit Quality Of Sweet Pepper Depending On Foliar Application Of Calcium, Halina Buczkowska, Zenia Michalojc, Renata Nurzynska-Wierdak

Turkish Journal of Agriculture and Forestry

The proper feeding of field plants is one of the most significant factors with an impact on their growth and development. Calcium is one of the basic nutrients of plants, crucial in many cell processes. Calcium in a plant is reutilized very poorly, and hence symptoms of deficiency of this component are observed on the youngest leaves, apexes of stems and roots, and, most importantly, on the fruits. The aim of this study was to evaluate the effects of foliar Ca feeding on the yield of sweet pepper 'Caryca F1' and on selected elements of its fruit quality in field …

Evaluating Soil Quality And Bioefficacy Study Of Cajanus Cajan L. In Coal Mine-Degraded Land, Shrabani Sen, Vipin Kumar

Turkish Journal of Agriculture and Forestry

Surface mining activities in past and recent times have resulted in the existence of a number of overburden dumps (mine spoils) through excavation and deposition of removed soil and rock debris. These spoils require environmental stabilization/restoration through proper revegetation. The present study was undertaken to examine the influence of various amendments to soil properties and the growth and yield of Cajanus cajan L. cultivation in mine-degraded soils. An experiment was conducted with nine combinations of various amendments to C. cajan L., a widely cultivating legume in India for its highly nutritious seeds. The physicochemical and biological properties of mine spoil …

Quality Traits Of Green Plums (Prunus Cerasifera Ehrh.) At Different Maturity Stages, Mehmet Ali̇ Saridaş, Nesi̇be Ebru Kafkas, Mozgan Zarifikhosroshahi, Onur Bozhaydar, Sevgi̇ Paydaş Kargi

Turkish Journal of Agriculture and Forestry

Fruits of 2 different plum cultivars (Prunus cerasifera Ehrh.) were collected in 2015 from 15-year-old trees in Hatay Province, Turkey. The 2 plum cultivars (Can and Gül) were on their own roots. Fruits were picked 5 times (both Can and Gül) at 12-day intervals (12 April [t1], 24 April [t2], 6 May [t3], 18 May [t4], and 30 May [t5]) during maturation in 2015. Higher levels of health-promoting components with the capacity to prevent several diseases, such as phenolic compounds with antioxidant activity, were found in the Can fruits, whereas the Gül fruits were characterized by lower values. The amounts …

การผลิตโปรตีเอสจากวัสดุเหลือทิ้งทางการเกษตรโดย Bacillus Pumilus, พัชราภรณ์ การงาน

Chulalongkorn University Theses and Dissertations (Chula ETD)

โปรตีเอสเป็นเอนไซม์ที่เร่งปฏิกิริยาการย่อยสลายโปรตีนให้เป็นกรดอะมิโน และเปปไทด์สายสั้นๆ ซึ่งสามารถนำไปประยุกต์ใช้ในการบำบัดน้ำเสียที่มีโปรตีนนมสูงจากร้านกาแฟได้ ซึ่งแบคทีเรียในสกุล Bacillus เป็นแบคทีเรียที่ผลิตโปรติเอสได้ดี โดย Bacillus pumilus มีความสามารถในการผลิตโปรติเอสปริมาณสูง ซึ่งคัดแยกได้จากบ่อน้ำพุร้อนทางภาคเหนือของประเทศไทย วิทยานิพนธ์นี้สนใจการผลิตโปรตีเอสจาก B. pumilus และศึกษาปัจจัยของแหล่งคาร์บอน และไนโตรเจน รวมถึงภาวะที่เหมาะสมต่อการผลิตโปรติเอส การผลิตโปรติเอสจาก B. pumilus มีค่ากิจกรรมของเอนไซม์โปรติเอสสูงที่สุด เท่ากับ 2.545 ยูนิตต่อมิลลิลิตร โดยเลี้ยงในอาหารสำหรับผลิตโปรติเอสประกอบด้วย 1 เปอร์เซ็นต์ โมลาส 1 เปอร์เซ็นต์ รำข้าว ภาวะในการเลี้ยงที่เหมาะสม คือ ค่าความเป็นกรด-ด่างเริ่มต้นในการเลี้ยงเท่ากับ 8.0 บ่มที่อุณหภูมิ 30 องศาเซลเซียส ความเร็วรอบ 250 รอบต่อนาที เป็นเวลา 24 ชั่วโมง ราคาอาหารเป็นหนึ่งในปัจจัยสำคัญสำหรับการผลิตโปรติเอส ดังนั้นการใช้วัสดุเหลือทิ้งทางการเกษตรเป็นแหล่งอาหารเลี้ยงเชื้อ เป็นการลดต้นทุนในการผลิตโปรตีเอส จึงเหมาะกับการนำไปประยุกต์ใช้ในระดับอุตสาหกรรม และการประยุกต์ใช้ในการบำบัดน้ำเสีย

Comparison Of Pcr Tests For The Detection Of Mycoplasma Agalactiae In Sheep And Goats, Hüban Göçmen, Ruben Sebastian Rosales, Roger David Ayling, Mi̇hri̇ban Ülgen

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to compare PCR tests for the detection of Mycoplasma agalactiae in sheep and goats. Samples obtained from sheep and goats in Turkey were tested to determine the presence of M. agalactiae. Mycoplasma culture and two direct PCR methods based on the uvrC gene and polC gene were compared with PCR of the 16S rRNA gene followed by denaturing gradient gel electrophoresis (PCR/DGGE) on DNA extracted from clinical samples (following culture enrichment). A total of 234 samples were examined: 9.4% and 13.2% were positive for M. agalactiae based on the uvrC gene and polC gene …

Genetic Analysis Of Avian Paramyxovirus Type I Strains Isolatedfrom Backyard Poultry In Iran, Fereshteh Sabouri, Mehdi Vasfi Marandi, Vahid Karimi, Mohammad Malekan, Mohsen Bashashati

Turkish Journal of Veterinary & Animal Sciences

Newcastle disease (ND) is one of the most serious diseases amongst many species of birds and causes huge economic losses in the poultry sector. Backyard poultry are the main source of food in rural areas of many developing countries and play a crucial role in the epidemiology of ND. The sequence of the F protein cleavage site is the major virulence determinant of Newcastle disease virus (NDV). The aim of this study was to understand the molecular characterization of F proteins of Iranian backyard poultry in NDVs. The complete open reading frame sequences of the F gene of six isolates …

"Boys Learn The Teacher, And Then They Learn The Subject": The Importance Of The Teacher-Student Relationship In Engaging High School Boys In The Writing Classroom, Leslie Ellis

Masters Theses

This thesis explores methods for engaging high school boys in the writing classroom. Chapter one describes the differing beliefs scholars have about boys' educational situation, specifically in English language arts. Several researchers and scholars describe boys' situation as dire because boys have failed to improve as girls have over the last sixty years. These researchers cite various reasons for boys' academic stagnation, such as learning styles, hormones, brain structure and development, the feminization of the classroom, motivation, engagement, and teaching styles. These factors may contribute to the gender gap in writing. Other scholars deny the urgency of boys' lack of …

Assessment Of The Efficacy Of The Hose-Bridge As A Road-Crossing Structure For Dekay's Brownsnake (Storeria Dekayi), Sarah Elizabeth Manka

Masters Theses

Various structures have been integrated into roadways to ensure the road does not impede wildlife movements between adjacent habitats. Where traffic volume is low, the costs of installing and maintaining such structures is typically prohibitive. I tested the efficacy of a hose-bridge deployed temporarily on a State Park road in Illinois that allowed the passage of cars over it and small wildlife species to cross through it. I predicted that, during the 4.5 -week period of peak migratory movement, road-based mortality of Dekay's Brownsnakes (Storeria dekayi) would be less at the site having the hose-bridge, when compared to a similar …

Structures And Nuclear Quadrupole Coupling Tensors Of 1,2-Dichloroethane, 1-Chloro-2-Fluoroethane And 2,3-Dichloropropene Studied Using Microwave Spectroscopy And Computational Chemistry, Asela Sampath Dikkumbura

Masters Theses

The Fourier-transform microwave (FTMW) spectra of 1,2-dichloroethane (12DCE), 1-chloro-2-fluoroethane (1C2FE) and 2,3-dichloropropene (23DCP) have been studied in the 6 to 18 GHz range to determine experimental rotational constants, nuclear quadrupole coupling constants (NQCC) and quartic centrifugal distortions constants. These three molecules have different spatial arrangements (anti and gauche) resulting from different relative orientations of chlorine and/or fluorine atoms about the C-C single bond. The lowest energy anti conformer of 12DCE is non-polar and it is not detectable by microwave spectroscopy, but rotational spectra of gauche-12DCE with three isotopologues, gauche-1C2FE with three isotopologues, and both anti- …

White-Rot Fungi As Pretreatment Agents For Wood Destined For Biofuel Applications, Ryan M. Kalinoski

Masters Theses

Efficient and economical conversion of lignocellulosic biomass to biofuels is often hampered by the chemical recalcitrance of the material. Inexpensive and environmentally-friendly pretreatment processes are therefore desirable in order to lower the cost of biofuel production and minimize negative environmental impacts. To that end, we have explored the use of a naturally occurring white-rot fungus, Trametes versicolor, as a direct pretreatment agent for hardwood destined for biofuel applications. Specifically, we examined the pretreatment effects on the hardwood mixture after treatment with the wild-type strain of T. versicolor (52J) compared with those from a cellobiose dehydrogenase (CDH)-deficient strain (m4D) , …

The Effects Of High Intensity Interval Training On Body-Esteem Among College-Aged Women, Chelsea K. Duncan

Masters Theses

The purpose of this study was to examine the effects of high intensity interval training (HIIT) on body-esteem among college-aged females. The study had four participants complete a pre-intervention questionnaire, which included BMI information and the Body-Esteem Scale (BES: Franzoi & Shields, 1984). The participants then completed 12 sessions of HIIT, three sessions each week for four weeks. After completing the HIIT protocol, participants filled out a post-intervention questionnaire, including BMI and the BES. The post-intervention questionnaires were then compared to the participants' pre-intervention questionnaires using a paired-samples t test with SPSS software. Small changes in BES scores occurred, however …

Expression Of Artemia Lea Proteins In Drosophila Melanogaster Cells Using Multicistronic Vector Constructs, Kazi Nazrul Islam

Masters Theses

In nature several organisms exhibit anhydrobiosis, the outstanding feature to survive in extreme desiccation by entering into a state of dormancy known as diapause. The cyst of the brine shrimp Artemia franciscana shows anhydrobiosis by entering into a diapause phase. Previous studies showed a correlation between anhydrobiosis and expression of highly hydrophilic polypeptides termed late embryogenesis abundant (LEA) proteins. However, the precise molecular mechanisms of LEA proteins are still unknown. The presence of multiple LEA proteins in Artemia suggests that some of them might work together. Here, I aimed to express different combination of two LEA proteins from Artemia franciscana …

Theoretical Investigations Of Difluorobenzene Interacting With Ne And Infrared Analysis Of 1,1-Dichloroethylene From Synchrotron Data, Seri P. Kamari

Masters Theses

The intermolecular interactions between two molecules are of great importance in proteins, polypeptides, DNA binding, and drug binding interactions. Dimers of chemical rings such as difluorobenzene with hydrogen containing molecules such as acetylene (HCCH) and atoms such as neon are classic systems for investigating weak interactions; however, the microwave spectrum of 1,2-difluorobenzene...Ne does not behave as expected. Possible explanation of this phenomenon is that there is some large amplitude motion perturbing the spectrum.

A computational study was performed to analyze the potential energy surface (PES) of Ne or Ar with ortho, meta, and para difluorobenzene, and reveal the …