Digital Commons Network^™

Serum Biomarkers Compared To Neural Imaging In The Differentiation Of Stroke Etiologies, Kevin Conboy

Physician Assistant Scholarly Project Posters

• Stroke is a leading cause of disability and morbidity and the fourth leading cause of death in the United States, and the second leading cause of death worldwide.

• Early restoration of blood flow is the most effective treatment of ischemic stroke by intravenous thrombolytic therapy within 3-4.5hrs of symptom onset.

• Patient outcomes have been shown to improve with earlier thrombolytics, each 15 minute increment increases survival by 3.0-4.0%.

• Non-contrast CT is the current standard for differentiation of stroke. It is beneficial due to speed of acquisition and its high sensitivity in ruling out hemorrhagic stroke.

• …

Sublingual Immunotherapy: Is It A Viable Option To Subcutaneous Immunotherapy When Treating Allergic Rhinitis?, David Ryan Kesterson

Physician Assistant Scholarly Project Posters

• Background: Allergic rhinitis (AR) is a very common debilitating disease that can be detrimental to one’s lifestyle, work, and home life. Immunotherapy is the only treatment option that has disease modifying capabilities with a proper therapeutic regimen. Subcutaneous immunotherapy (SCIT) was developed over 100 years ago and has been the gold standard in immunotherapy for many years in the United States. During these years many adverse reactions have been reported with SCIT along with non-adherence to total treatment. The introduction of sublingual immunotherapy (SLIT) over 20 years ago gave providers a promising alternative to SCIT.

• Method: A review …

Vitamin D Supplementation And Systemic Lupus Erythematosus, Pamela Rangen

Physician Assistant Scholarly Project Posters

• Patients with systemic lupus erythematosus (SLE) are prone to hypovitaminosis D because of their photosensitivity.

• Vitamin D has beneficial effects not only on bone metabolism but also on the function of the immune system.

• Vitamin D levels depend on many variables, including sun exposure, age, ethnicity, body mass index, use of medications and supplements.

• Patients with SLE avoid the sun because of photosensitive rashes and potential for disease flare, so adequate oral supplementation is critical.

• In addition, to the traditional known metabolic activities, vitamin D has been shown to modulate the immune system, and its …

A Comparison Of Traditional Care And Cognitive Behavioral Therapy For Treating Depression Following Open Heart Surgery, Derryk Allen

Physician Assistant Scholarly Project Posters

Depression occurs shortly after open heart surgery in many patients. When depression is identified, traditional treatment consists of antidepressant medications along with cardiac rehabilitation and follow up care but these visits may not address depression. The purpose of this study compares traditional care with cognitive behavioral therapy. Does cognitive behavioral therapy more effectively manage depression than traditional care among male and female patients that have undergone open-heart surgery and acquired depressive symptoms? An article search of the following databases was conducted: PubMed and The Cochran Library. The review of literature explored studies that compare treatment between traditional care and CBT …

16. A Comparison Of Soil Biodiversity In Restored Prairie Plots And Agricultural Fields At A Biomass Production Farm In Southeastern Minnesota, Bruno Borsari, Neal Mundahl, Malcolm Vidrine

North American Prairie Conference Proceedings

Communities of soil-dwelling organisms contribute to soil fertility and nutrient cycling, but conventional farming practices can disturb and reduce these communities. In southeastern Minnesota, some farmers are planting simplified prairie vegetation to produce biomass fuels. Our study was designed to assess the species abundance and diversity of soil invertebrates in plantings of mixed grasses only (MG) and mixed grasses with forbs (MGF) that were planted for use as a biomass fuel source on a farm in southeastern Minnesota in 2007. Abundance and diversity of soil invertebrates also were examined in soils of corn (Zea mays L.) fields grown on the …

The Wetted Ramp As A Useful Tool To Service Smaller-Bodied Finfishes At Low-Head Acquatic Barriers, Levi Kivari

Master's Theses and Doctoral Dissertations

This study examined the effects of finfish length and behavior on passage success on the wetted ramp, a proposed passage device for finfishes at low-head aquatic barriers. There were two hypotheses: there is a size effect to passage success because larger fish have relatively less propulsive surface area in partial submersion, and fish respond to changes in ramp angle of inclination during a passage attempt. Creek chub (Semotilus atromaculatus) and white sucker (Catostomus commersonii) were observed, using a high speed camera, as they attempted to scale the wetted ramp. Smaller fish traveled farther and were also able to accelerate on …

Crayfish As A Biomonitor For The Algal Toxin Microcystin-Lr, Kayla Mcrobb

Master's Theses and Doctoral Dissertations

The bloom-forming alga Microcystis produces the hepatotoxin microcystin-LR. Removing this toxin from drinking water requires expensive treatments; current analytical methods are incapable of real-time monitoring. Crayfish are resistant to microcystin-LR toxicity and respond well to operant conditioning. I hypothesized that crayfish could sense and be trained to respond to microcystin-LR via electroshocks for use as biomonitors. In the microcystin detection experiment, Procambarus clarkii moved away from microcystin-LR (p < 0.001) while Orconectes rusticus did not respond (p = 0.28). Neither species could be reliably trained to move to the tank’s center when microcystin-LR was present. To understand why, I tested Procambarus clarkii’s ability to respond to a neutral scent using positive and negative reinforcement. They associated the scent with positive reinforcement (p < 0.001) but not negative reinforcement (p = 0.21), suggesting crayfish may be incapable of associating scents with negative tactile stimuli.

Gender And Non-Normative Sex In Sub-Saharan Africa, Johanna Bond

Michigan Journal of Gender & Law

This Article argues for the adoption of a gender-based framework to supplement rights promotion strategies and campaigns based on LGBTI identity. The Article draws upon feminist, queer, and trans theory to develop an expansive understanding of gender within international human rights law. An analysis incorporating such theory will catalyze more systematic promotion of LGBTI rights. Although the approach is applicable across a variety of geographic contexts, this Article uses sub-Saharan Africa as an illustrative case study. A focus on gender rights as supplementary to and interrelated with LGBTI rights offers both conceptual and pragmatic benefits in the struggle to promote …

Cultivate Spring/Summer 2016, Utah State University

Cultivate Magazine

No abstract provided.

17. Prairie Reverie: What Does The Word Prairie Mean In Postprairie Illinois?, Jack Shouba

North American Prairie Conference Proceedings

The meaning of the word ‘‘prairie’’ seems to have changed in recent years, as the Silicon Prairie replaced the Silphium prairie. There are bewildering uses of prairie that have nothing to do with native grasslands. The word is often used in a generic way, such as calling farmland, a vacant lot, or other open space a prairie. It is frequently used evocatively, as in Lakewood Prairie, a subdivision without a lake, a wood, or a prairie; a shopping center with no prairie for miles around is called Prairie View. Oxymorons like prairie golf or prairie fishing are common. Prairie reverie …

03. Population Demographics Of The Loggerhead Shrike: Insights Into The Species Decline From A Long-Term Study In The Midewin National Tallgrass Prairie, Amy A. Chabot, Fran Harty, James Herkert, William Glass

North American Prairie Conference Proceedings

We monitored a breeding population of loggerhead shrikes (Lanius ludovicianus) in the Midewin National Tallgrass Prairie from 2005 to 2016. Demographic data were compiled annually, including information on population size, age structure, and reproductive success. We banded adult shrikes, with some additional effort focused on nestlings (2005–2007) and independent hatch-year birds (2014–2016). We measured return rate as the number of birds that were previously banded. Site reuse rates were quantified as the use of a breeding territory in multiple years. Site fidelity, the use of a site by the same male or female in consecutive years, and dispersal distance of …

09. Matching Long-Term Fire Effects Research To Pressing Questions Facing Tallgrass Prairie Managers Across The Upper Midwest, Tom Bragg, Craig Maier, Yari Johnson

North American Prairie Conference Proceedings

The goal for this paper is to explore how a network of coordinated prescribed fire experiments could be developed and applied to tallgrass prairie management. In a 2011 survey conducted by the Tallgrass Prairie and Oak Savanna Fire Science Consortium in their region, 61% of 207 land managers indicated that their greatest need with respect to fire regimes was information on the outcome of variations in fire frequency and season, with information on these variables ranging from limited to completely lacking. Need for this kind of information was echoed during a breakout discussion session at the 2016 North American Prairie …

Enscat: Clustering Of Categorical Data Via Ensembling, Bertrand S. Clarke, Saeid Amiri, Jennifer L. Clarke

Department of Statistics: Faculty Publications

Background: Clustering is a widely used collection of unsupervised learning techniques for identifying natural classes within a data set. It is often used in bioinformatics to infer population substructure. Genomic data are often categorical and high dimensional, e.g., long sequences of nucleotides. This makes inference challenging: The distance metric is often not well-defined on categorical data; running time for computations using high dimensional data can be considerable; and the Curse of Dimensionality often impedes the interpretation of the results. Up to the present, however, the literature and software addressing clustering for categorical data has not yet led to a standard …

Genomic Bayesian Prediction Model For Count Data With Genotype X Environment Interaction, Abelardo Montesinos-López, Osval A. Montesinos-López, José Crossa, Juan Burgueño, Kent M. Eskridge, Esteban Falconi-Castillo, Xinyao He, Pawan Singh, Karen Cichy

Department of Statistics: Faculty Publications

Genomic tools allow the study of the whole genome, and facilitate the study of genotype-environment combinations and their relationship with phenotype. However, most genomic prediction models developed so far are appropriate for Gaussian phenotypes. For this reason, appropriate genomic prediction models are needed for count data, since the conventional regression models used on count data with a large sample size (n_T ) and a small number of parameters (p) cannot be used for genomic-enabled prediction where the number of parameters (p) is larger than the sample size (n_T ). Here, we propose a Bayesian mixed-negative binomial (BMNB) genomic …

Minority Librarians In Higher Education: A Critical Race Theory Analysis, Kelli Johnson

Theses, Dissertations and Capstones

The library profession as a whole is predominantly white with a large discrepancy between the percentage of minorities in the United States in general and the percentage of professional librarians who are minorities. Despite past recruitment efforts, there remains a dearth of minority librarians in higher education and the reasons for this remain unclear. The purpose of this qualitative study was to investigate minority librarian experiences in higher education and their perceptions of supports and barriers encountered in becoming and being professional librarians. Five themes emerged from the data. The first theme pertained to the spirit of service and activism …

Age Of Kindergarten Entry And Rate Of Specific Learning Disabilities, Elizabeth A. Crum

Theses, Dissertations and Capstones

Kindergarten age eligibility requirements vary from state to state; however, school districts typically admit children into kindergarten in the fall following a student’s fifth birthday. Research on the outcomes of five-year-old children and children whose entry was delayed until age six is contradictory. The current study was conducted to add to the existing literature to assist families and policy makers with decision making regarding appropriate kindergarten entry age. The sample included 541 second through seventh grade students from a small rural school district. Actual and predicted counts of students who were later found eligible for specific learning disabilities were examined …

"The Crescent" Student Newspaper, February 4, 2016, George Fox University Archives

"The Crescent" Student Newspaper

Student newspaper of George Fox University.

"The Crescent" Student Newspaper, February 4, 2016, George Fox University Archives

"The Crescent" Student Newspaper

Student newspaper of George Fox University.

Politically Correct Eugenics, Seema Mohapatra

Faculty Scholarship

No abstract provided.

Annual Higher Ground Women's Leadership Conference 2016, The Grace E. Harris Leadership Institute At Virginia Commonwealth University

The Grace E. Harris Leadership Institute Publications

No abstract provided.

Virginia Commonwealth University Fall Commencement Program [2016], Virginia Commonwealth University

VCU Commencement Programs

No abstract provided.

Article Iii Standing For Private Plaintiffs Challenging Greenhouse Gas Regulations, Bradford Mank

Faculty Articles and Other Publications

An important unresolved question is whether non-state plaintiffs have standing under Article III of the U.S. Constitution to sue in federal courts in climate change cases. In Massachusetts v. EPA, the Supreme Court held a state government could sue the U.S. government to address climate change issues, and suggested, but did not decide, that private litigants might have lesser rights than states. In Washington Environmental Council v. Bellon, the Ninth Circuit held that private groups did not have standing to challenge Washington State’s failure to regulate greenhouse gas (GHG) emissions from five oil refineries, and implied that private plaintiffs may …

The Prostaglandin E2-Ep3 Receptor Axis Regulates Anaplasma Phagocytophilum-Mediated Nlrc4 Inflammasome Activation, Xiaowei Wang, Dana K. Shaw, Holly L. Hammond, Fayyaz S. Sutterwala, Manira Rayamajhi, Kari Ann Shirey, Darren J. Perkins, Joseph V. Bonventre, Thangam S. Velayutham, Sean M. Evans, Kyle G. Rodino, Lauren Viebrock, Karen M. Scanlon, Nicholas H. Carbonetti, Jason A. Carlyon, Edward A. Miao, Jere W. Mcbride, Michail Kotsyfakis, Joao H. F. Pedra

Microbiology and Immunology Publications

Rickettsial agents are sensed by pattern recognition receptors but lack pathogen-associated molecular patterns commonly observed in facultative intracellular bacteria. Due to these molecular features, the order Rickettsiales can be used to uncover broader principles of bacterial immunity. Here, we used the bacterium Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis, to reveal a novel microbial surveillance system. Mechanistically, we discovered that upon A. phagocytophilum infection, cytosolic phospholipase A2 cleaves arachidonic acid from phospholipids, which is converted to the eicosanoid prostaglandin E2 (PGE2) via cyclooxygenase 2 (COX2) and the membrane associated prostaglandin E synthase-1 (mPGES-1). PGE2-EP3 receptor signaling leads …

First Trimester Vaginal Microbiome As Pregnancy Outcome Predictor, Sarah K. Rozycki, Jennifer M. Fettwis

MD Student Summer Research Fellowship Program Posters

• We have developed clinical definiKons of healthy and complicated pregnancies based on pathologies that will be used in future VaHMP studies.

• Although one study7 found dysbioKc vagitypes in all three semesters of women who had PPROM, none of our PPROM subjects had a BVAB1 vagitype, and there were equal Gardnerella vaginalis vagitypes in both the controls and subjects who had PPROM (Fig. 2).

• While there were more PPROM subjects with Lactobacillus iners vagitypes, this Lactobacillus is less protecKve as it can coexist with pathogenic anaerobic bacteria.

• “Candidatus Mycoplasma girerdii”, Lactobacillus jensenii, and Ureaplasma were significantly associated …

Tumor-Reactive Immune Cells Protect Against Metastatic Tumor And Induce Immunoediting Of Indolent But Not Quiescent Tumor Cells, Kyle K. Payne, Rebecca Keim, Laura Graham, Michael O. Idowu, Wen Wan, Xiang-Yang Wang, Amir A. Toor, Harry D. Bear, Masoud H. Manjili

Massey Comprehensive Cancer Center Publications

Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens. To overcome these barriers, we reprogrammed tumor-immune cell cross-talk by combined use of decitabine and adoptive immunotherapy, containing tumor-sensitized T cells and CD25⁺ NKT cells. Decitabine functioned to induce the expression of highly immunogenic cancer testis antigens in the tumor, while also reducing the frequency of myeloid-derived suppressor cells and the presence of CD25⁺ NKT cells rendered T cells, resistant to remaining myeloid-derived suppressor cells. This combinatorial therapy significantly prolonged survival of animals bearing metastatic tumor …

Tower-Based Greenhouse Gas Fluxes In A Restored Tidal Freshwater Wetland: A Shared Resource For Research And Teaching., Ellen J. Stuart-Haëntjens, Scott C. Neubauer, Christopher M. Gough

Rice Rivers Center Research Symposium

The goals of this study are: 1) to use an eddy-covariance system to continuously measure wetland-atmosphere CO2 and CH4 exchange in a restored forested wetland, 2) to quantity C sequestration in plant biomass and soils in restored (Kimages Creek watershed) and old-growth (Harris Creek watershed) forested wetlands, and 3) to establish a shared long-term, shared research and teaching platform centered on eddy-covariance tower measurements. Since the old-growth forest wetland has had longer to accumulate C, the current C stocks are likely much larger than those of the restored wetland; however, the rate of C accumulation (i.e., C sequestration or net …

Wood Frog And Spotted Salamander Abundance Across Pool Types And Wetland Networks At Fort A.P. Hill, Va, Logan Mcdonald, Will Fields, Katelyn Horn, James R. Vonesh, Kristine Grayson

Rice Rivers Center Research Symposium

Effective management of pond breeding amphibians requires identifying suitable breeding habitat and its use by different species. Suitable breeding habitat is largely characterized by pool type, physical habitat, and position within the landscape. Parameters such as vegetative cover, hydrology, and water chemistry are known to influence amphibian occupancy of vernal pools. While seasonal vernal pools have been the focus of conservation efforts, pools that are an artifact of anthropogenic disturbance, such as road ruts, may be an important component of the landscape for amphibians. The role of wetland isolation within a landscape has been well studied, but less consideration has …

Skeletal Muscle Mass And Composition During Mammalian Hibernation, Clark J. Cotton

Biology Faculty Publications

Hibernation is characterized by prolonged periods of inactivity with concomitantly low nutrient intake, conditions that would typically result in muscle atrophy combined with a loss of oxidative fibers. Yet, hibernators consistently emerge from winter with very little atrophy, frequently accompanied by a slight shift in fiber ratios to more oxidative fiber types. Preservation of muscle morphology is combined with down-regulation of glycolytic pathways and increased reliance on lipid metabolism instead. Furthermore, while rates of protein synthesis are reduced during hibernation, balance is maintained by correspondingly low rates of protein degradation. Proposed mechanisms include a number of signaling pathways and transcription …

Annual Report, 2015-2016, University Of Arkansas, Fayetteville. Libraries

University Libraries Annual Report

No abstract provided.

Exposing Artemia Salina To Chattonella Subsalsa: A General Toxicity Test, Nicholas Picha

Bridges: A Journal of Student Research

The raphidophyte Chattonella subsalsa has been reported to cause harmful algal blooms in every major ocean. In South Carolina, C. subsalsa blooms have been observed in brackish stormwater detention ponds as well as estuarine waters neighboring urbanized areas. Blooms frequently cause fish kills although the fish kill mechanism of C. subsalsa is currently unknown. In many harmful species, the lethality of algal cells is thought to correspond with algal growth phase. Algal growth is known to progress through five distinct phases; lag, early exponential, late exponential, stationary, and decline. In nature, harmful algal blooms commonly occur in the late exponential …