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A Historical Perspective Of The Biology And Conservation Of The Kemp's Ridley Sea Turtle, Thane Wibbels, Elizabeth Bevan

Gulf of Mexico Science

The history of the critically endangered Kemp’s ridley sea turtle (Lepidochelys kempii) has presented scientists and conservationists with a variety of questions and challenges originating in part from the species’ limited distribution and single primary nesting beach. Although the species was initially brought to the attention of the scientific community in 1880 by Richard Kemp, more than 80 yr passed before Henry Hildebrand revealed the location of its primary nesting beach at Rancho Nuevo, Mexico in the western Gulf of Mexico. By the time scientists began estimating the number of females nesting at Rancho Nuevo, it appeared that …

Kemp's Ridley Sea Turtle (Lepidochelys Kempii) Nesting On The Texas Coast: Geographic, Temporal, And Demographic Trends Through 2014, Donna J. Shaver, Cynthia Rubio, Jennifer Shelby Walker, Jeffrey George, Anthony F. Amos, Kimberly Reich, Curtis Jones, Thomas Shearer

Gulf of Mexico Science

Kemp’s ridley (Lepidochelys kempii) is the world’s most endangered sea turtle species, and nests primarily on the Gulf of Mexico coast in Mexico. In 1978, a binational project was initiated to form a secondary nesting colony of this species in south Texas at Padre Island National Seashore (PAIS), as a safeguard against extinction. During 1978–2014, we documented 1,667 Kemp’s ridley nests in Texas, with 56% found at PAIS. Most nests (89%) found in south Texas were from wild-stock turtles; south Texas is the northern extent of the documented historic nesting range for the species. We documented nesting in …

Thousands Of Single Nucleotide Polymorphisms In The Critically Endangered Kemp's Ridley Sea Turtle (Lepidochelys Kempii) Revealed By Double-Digest Restriction-Associated Dna Sequencing: Opportunities For Previously Elusive Conservation Genetics Research, Luis A. Hurtado, Xochitl De La Rosa-Reyna, Mariana Mateos, Donna J. Shaver, Richard Metz, John Thiltges, Joshua Hill, Miguel A. Reyes-Lopez, Charlie Johnson

Gulf of Mexico Science

No abstract provided.

College Catalog, 2016-2017, Graduate, Buffalo State College

Academic Catalogs, 1871-2018

No abstract provided.

Translational Significance Of Heme Oxygenase In Obesity And Metabolic Syndrome, Nader G. Abraham, Joshua M. Junge, George S. Drummond

NYMC Faculty Publications

The global epidemic of obesity continues unabated with sequelae of diabetes and metabolic syndrome. This review reflects the dramatic increase in research on the role of increased expression of heme oxygenase (HO)-1/HO-2, biliverdin reductase, and HO activity on vascular disease. The HO system engages with other systems to mitigate the deleterious effects of oxidative stress in obesity and cardiovascular disease (CVD). Recent reports indicate that HO-1/HO-2 protein expression and HO activity have several important roles in hemostasis and reactive oxygen species (ROS)-dependent perturbations associated with metabolic syndrome. HO-1 protects tissue during inflammatory stress in obesity through the degradation of pro-oxidant …

Events & Outreach; 2016-04-30; Sojourner Truth Award, Catherine Collins

Events and Outreach

No abstract provided.

Contributions Of Tropodithietic Acid And Biofilm Formation To The Probiotic Activity Of Phaeobacter Inhibens, Marta Gomez-Chiarri, David C. Rowley, David R. Nelson

Cell and Molecular Biology Faculty Publications

Background: The probiotic bacterium Phaeobacter inhibens strain S4Sm, isolated from the inner shell surface of a healthy oyster, secretes the antibiotic tropodithietic acid (TDA), is an excellent biofilm former, and increases oyster larvae survival when challenged with bacterial pathogens. In this study, we investigated the specific roles of TDA secretion and biofilm formation in the probiotic activity of S4Sm.

Results: Mutations in clpX (ATP-dependent ATPase) and exoP (an exopolysaccharide biosynthesis gene) were created by insertional mutagenesis using homologous recombination. Mutation of clpX resulted in the loss of TDA production, no decline in biofilm formation, and loss of the ability …

Control Of Sexuality By The Sk1-Encoded Udp-Glycosyltransferase Of Maize, Andrew P. Hayward, Maria A. Moreno, Thomas P. Howard Iii, Joel Hague, Kimberly Nelson, Christopher Heffelfinger, Sandra Romero, Albert P. Kausch, Gaétan Glauser, Ivan F. Acosta, John P. Mottinger, Stephen L. Dellaporta

Cell and Molecular Biology Faculty Publications

Sex determination in maize involves the production of staminate and pistillate florets from an initially bisexual floral meristem. Pistil elimination in staminate florets requires jasmonic acid signaling, and functional pistils are protected by the action of the silkless 1 (sk1) gene. The sk1 gene was identified and found to encode a previously uncharacterized family 1 uridine diphosphate glycosyltransferase that localized to the plant peroxisomes. Constitutive expression of an sk1 transgene protected all pistils in the plant, causing complete feminization, a gain-of-function phenotype that operates by blocking the accumulation of jasmonates. The segregation of an sk1 transgene was used …

State-Of-The-Art Monitoring In Treatment Of Dengue Shock Syndrome: A Case Series, Steven L. Moulton, Jane Mulligan, Anon Srikiatkhachorn, Siripen Kalayanarooj, Greg Z. Grudic, Sharone Green, Robert V. Gibbons, Gary W. Muniz, Carmen Hinojosa-Laborde, Alan L. Rothman, Stephen J. Thomas, Victor A. Convertino

Cell and Molecular Biology Faculty Publications

Background

Early recognition and treatment of circulatory volume loss is essential in the clinical management of dengue viral infection. We hypothesized that a novel computational algorithm, originally developed for noninvasive monitoring of blood loss in combat casualties, could: (1) indicate the central volume status of children with dengue during the early stages of “shock”; and (2) track fluid resuscitation status.

Methods

Continuous noninvasive photoplethysmographic waveforms were collected over a 5-month period from three children of Thai ethnicity with clinical suspicion of dengue. Waveform data were processed by the algorithm to calculate each child’s Compensatory Reserve Index, where 1 represents supine …

Privacy And Accountability In Black-Box Medicine, Roger Allan Ford, W. Nicholson Price Ii

Law Faculty Scholarship

Black-box medicine—the use of big data and sophisticated machine learning techniques for health-care applications—could be the future of personalized medicine. Black-box medicine promises to make it easier to diagnose rare diseases and conditions, identify the most promising treatments, and allocate scarce resources among different patients. But to succeed, it must overcome two separate, but related, problems: patient privacy and algorithmic accountability. Privacy is a problem because researchers need access to huge amounts of patient health information to generate useful medical predictions. And accountability is a problem because black-box algorithms must be verified by outsiders to ensure they are accurate and …

Rockingham County, State Of New Hampshire, 2015 Annual Report Year Ending December 31, 2015., Rockingham County Representatives

Rockingham County, NH Annual Reports

This is an annual report containing vital statistics for a county in the state of New Hampshire.

Towards An Open Grapevine Information System, A-F Adam-Blondon, M. Alaux, C. Pommier, D. Cantu, Z-M Cheng, Gr Cramer, C. Davies, S. Delrot, L. Deluc, G. Di Gaspero, J. Grimplet, A. Fennell Dr, Et. Al

Agronomy, Horticulture and Plant Science Faculty Publications

Viticulture, like other fields of agriculture, is currently facing important challenges that will be addressed only through sustained, dedicated and coordinated research. Although the methods used in biology have evolved tremendously in recent years and now involve the routine production of large data sets of varied nature, in many domains of study, including grapevine research, there is a need to improve the findability, accessibility, interoperability and reusability (FAIR-ness) of these data. Considering the heterogeneous nature of the data produced, the transnational nature of the scientific community and the experience gained elsewhere, we have formed an open working group, in the …

2016 The Lindenwood Review, Lindenwood University

State of the University Address (Formerly Annual Reports or President's Reports/)

The 2016 annual report of Lindenwood University. This issue includes a donor report.

Validity Of The Promis Physical Performance Scale In Determining Frailty And Physical Ability In Community-Dwelling Elderly, Jeff Houck, Tomoko Iwanaga, Christine Kieu, Keegan Lerma, Chelan Murasaki, Tawny Souza

Student-Faculty Research - College of Physical Therapy

In many clinical settings, therapists are continuously seeking efficient and valid assessments for older adults to determine their physical abilities and functional status. The Patient Reported Outcome Instrument System (PROMIS) is a newly developed computer adapted test (CAT) that is being incorporated into electronic medical records and has been reported to assess a person’s physical function. The current gold standard to assess different levels of frailty and physical function in older individuals is the Modified Physical Performance Test (mPPT). However, the mPPT is a lengthy performance based outcome measure that takes time to administer. The purpose of this study is …

City Of Portsmouth, New Hampshire Annual Comprehensive Financial Report For The Year Ended June 30, 2016., Portsmouth Town Representatives

Portsmouth, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Macalester Today Winter 2016, Macalester College

Macalester Today

No abstract provided.

Getting ‘In’ And ‘Out Of Alignment’: Some Insights Into The Cultural Imagery Of Fitness From The Perspective Of Experienced Gym Adherents, Ross D. Neville, Catherine Gorman

Articles

While the identification of risks associated with sedentary lifestyles provided a strong foundation for what we understand by ‘fitness’ today, research across the social sciences and humanities has been rather more ambivalent about the term. One important cause for concern here is the cultural proximity of ‘fitness’ to consumer culture by means of the ‘fitness industry’. It has been shown, for example, that the pursuit of fitness has become increasingly, if not exclusively, a matter of attending to the body as a marker of social status: something to be consumed for; something to be consumed by others. In this paper, …

Brotherhood And The Quest For African American Social Equality: A Story Of Phi Beta Sigma, Wendy Marie Laybourn, Gregory S. Parks

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.

The Greening Of Faith: God, The Environment, And The Good Life (20th Anniversary Edition), John E. Carroll, Paul Brockelman, Mary Westfall

University of New Hampshire Press: Open Access Books

The recent release of Pope Francis’s much-discussed encyclical on the environment, Laudato Si’: On Care for Our Common Home, has reinforced environmental issues as also moral and spiritual issues. This anthology, twenty years ahead of the encyclical but very much in line with its agenda, offers essays by fifteen philosophers, theologians, and environmentalists who argue for a response to ecology that recognizes the tools of science but includes a more spiritual approach—one with a more humanistic, holistic view based on inherent reverence toward the natural world. Writers whose orientations range from Buddhism to evangelical Christianity to Catholicism to Native American …

Undergraduate Catalog Of Studies, 2015-2016, University Of Arkansas, Fayetteville

Undergraduate Catalog of Studies

No abstract provided.

Graduate Programs Course Catalog 2016-2017

Bryant University Graduate School Course Catalog

No abstract provided.

How Often Are Antibiotic-Resistant Bacteria Said To “Evolve” In The News?, Nina Singh, Matthew T. Sit, Deanna M. Chung, Ana A. Lopez, Ranil Weerackoon, Pamela J. Yeh

Department of Statistics: Faculty Publications

Media plays an important role in informing the general public about scientific ideas.We examine whether the word “evolve,” sometimes considered controversial by the general public, is frequently used in the popular press. Specifically, we ask how often articles discussing antibiotic resistance use the word “evolve” (or its lexemes) as opposed to alternative terms such as “emerge” or “develop.” We chose the topic of antibiotic resistance because it is a medically important issue; bacterial evolution is a central player in human morbidity and mortality. We focused on the most widely-distributed newspapers written in English in the United States, United Kingdom, Canada, …

Systematic Evaluation Of The Impact Of Chip-Seq Read Designs On Genome Coverage, Peak Identification, And Allele-Specific Binding Detection, Qi Zhang, Xin Zeng, Sam Younkin, Trupti Kawli, Michael P. Snyder, Sündüz Kele

Department of Statistics: Faculty Publications

Background: Chromatin immunoprecipitation followed by sequencing (ChIP-seq) experiments revolutionized genome-wide profiling of transcription factors and histone modifications. Although maturing sequencing technologies allow these experiments to be carried out with short (36–50 bps), long (75–100 bps), single-end, or paired-end reads, the impact of these read parameters on the downstream data analysis are not well understood. In this paper, we evaluate the effects of different read parameters on genome sequence alignment, coverage of different classes of genomic features, peak identification, and allele-specific binding detection.

Results: We generated 101 bps paired-end ChIP-seq data for many transcription factors from human GM12878 and MCF7 cell …

Sex-Specific Hippocampal 5-Hydroxymethylcytosine Is Disrupted In Response To Acute Stress, Ligia A. Papale, Sisi Li, Andy Madrid, Qi Zhang, Li Chen, Pankaj Chopra, Peng Jin, Sunduz Keles, Reid S. Alisch

Department of Statistics: Faculty Publications

Environmental stress is among the most important contributors to increased susceptibility to develop psychiatric disorders. While it is well known that acute environmental stress alters gene expression, the molecular mechanisms underlying these changes remain largely unknown. 5-hydroxymethylcytosine (5hmC) is a novel environmentally sensitive epigenetic modification that is highly enriched in neurons and is associated with active neuronal transcription. Recently,we reported a genome-wide disruption of hippocampal 5hmCin male mice following acute stress that was correlated to altered transcript levels of genes in known stress related pathways. Since sex-specific endocrine mechanisms respond to environmental stimulus by altering the neuronal epigenome, we examined …

A Compendium Of Chromatin Contact Maps Reveals Spatially Active Regions In The Human Genome, Anthony D. Schmitt, Ming Hu, Inkyung Jung, Zheng Xu, Yunjiang Qiu, Catherine L. Tan, Yun Li, Shin Lin, Yiing Lin, Cathy L. Barr, Bing Ren

Department of Statistics: Faculty Publications

The three-dimensional configuration of DNA is integral to all nuclear processes in eukaryotes, yet our knowledge of the chromosome architecture is still limited. Genome-wide chromosome conformation capture studies have uncovered features of chromatin organization in cultured cells, but genome architecture in human tissues has yet to be explored. Here, we report the most comprehensive survey to date of chromatin organization in human tissues. Through integrative analysis of chromatin contact maps in 21 primary human tissues and cell types, we find topologically associating domains highly conserved in different tissues. We also discover genomic regions that exhibit unusually high levels of local …

Hiview: An Integrative Genome Browser To Leverage Hi‑C Results For The Interpretation Of Gwas Variants, Zheng Xu, Guosheng Zhang, Qing Duan, Shengjie Chai, Baqun Zhang, Cong Wu, Fulai Jin, Feng Yue, Yun Li, Ming Hu

Department of Statistics: Faculty Publications

Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex traits and diseases. However, most of them are located in the non-protein coding regions, and therefore it is challenging to hypothesize the functions of these non-coding GWAS variants. Recent large efforts such as the ENCODE and Roadmap Epigenomics projects have predicted a large number of regulatory elements. However, the target genes of these regulatory elements remain largely unknown. Chromatin conformation capture based technologies such as Hi-C can directly measure the chromatin interactions and have generated an increasingly comprehensive catalog of the interactome between the distal regulatory elements …

Identification And Sequence Analysis Of Alkaloid Biosynthesisgenes In Papaver Section Oxytona, Yağiz Alagöz, Tuğba Gürkök, İskender Parmaksiz, Turgay Ünver

Turkish Journal of Biology

The benzylisoquinoline alkaloids (BIA) are secondary metabolites that are produced by many of the Papaver species including Papaver bracteatum, Papaver pseudo-orientale, and Papaver orientale, three representative members of the section Oxytona Bernh. The sequences and expression levels of the genes positioned on the BIA biosynthesis pathway were previously defined in opium poppy (Papaver somniferum), one of the mostly studied species of the same genus. Nevertheless, the majority of predicted BIA-related gene sequences in the section Oxytona have not been specified. Here we are presenting new cDNA sequences that belong to the Oxytona species. In this study, partial sequences of norcoclaurine-6-O-methyltransferase …

Chondroitin Sulfate-Based Biomaterials For Tissue Engineering, Hyuck Joon Kwon, Youngbae Han

Turkish Journal of Biology

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) that is usually found attached to proteins as part of a proteoglycan. The use of CS-based biomaterials in the field of tissue engineering applications has been intensively growing over the past decades because CS is a biopolymer with the major advantages of being biodegradable, biocompatible, easily available, and highly versatile. In vitro and in vivo studies have shown that CS-based biomaterials upregulate cartilage-specific gene expression in chondrocytes and mesenchymal stem cells and also support osteogenic differentiation by increasing the effectiveness of bone anabolic growth factors. Chondroitin sulfate proteoglycan plays a key role …

Antisenescence Activity Of G9a Inhibitor Bix01294 On Human Bone Marrow Mesenchymal Stromal Cells, Min-Ji Ahn, Sin-Gu Jeong, Goang Won Cho

Turkish Journal of Biology

Alterations in epigenomic patterns are associated with diverse physiological functions and pathological mechanisms causing aging-related diseases, such as degenerative disorders and cancers. We investigated the senescent effects of BIX01294, a G9a (histone methyltransferase) inhibitor, in human bone marrow mesenchymal stromal cells (hBM-MSCs). We determined the optimal dose and time of BIX01294 treatment in hBM-MSCs to be 1 μM and 12 h, respectively. Under these conditions, the expression of the antisenescent genes TERT, bFGF, VEGF, and Oct-4 increased, whereas the expression of the senescent factors p16, p21, and p53 decreased. The number of β-galactosidase-positive cells decreased significantly, and the rates of …

Rejuvenation Of Mature Lentisk By Micrografting And Evaluation Of Genetic Stability, Ahmet Onay, Engi̇n Ti̇lkat, Veysel Süzerer, Özge Karakaş Meti̇n, Yelda Özden Çi̇ftçi̇, Fati̇h Mehmet Kilinç, İbrahi̇m Koç, Muhammet Şaki̇roğlu, Hakan Yildirim, Ahu Altinkut Uncuoğlu, Nazan Çalar, Ömer Faruk Akdemi̇r

Turkish Journal of Biology

An in vitro propagation method was established for both male and female genotypes of lentisk using actively growing shoot tips derived from forcefully lignified shoots. The effects of growth regulators on in vitro morphogenesis were investigated. Since rooting of the regenerated shoots for both genotypes was not achieved, an in vitro micrografting method was developed for the production of plantlets. Moreover, genetic stability of 3-, 6-, and 24-times subcultured clones of both genotypes was assessed and compared with the mother plants using fluorescent-based amplified fragment length polymorphism (AFLP) analysis. The set of main plants and the different subcultured clones were …