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2016 Annual Joint Report Of Pre-Kindergarten Through Higher Education In Tennessee, Tennessee. State Board Of Education, Tennessee Higher Education Commission

Annual Joint Reports

This report includes, but is not limited to, a discussion of the following four areas: minimizing duplication, compatibility, state needs in education, and master plan fulfillment.

Effects Of Chemical Preservatives On Weights And Lengths Of Bluegill Larvae, Scott M. Welch, Gregory A. Dudenhoeffer, Thomas R. Omara-Alawla

Cooperative Extension Research Publications

Measuring the lenghts and weights of live fish larvae can be tedious and time-consuming. This constraint could be alleviated by preserving the fish larvae in appropriate chemicals for later measurements. There is little or no information on the effects of preservatives on Bluegill larvae. The objective of this study was to determine the effects of five different common preservatives on Bluegill larvae. Individual weights and lengths of fish were measured and then the larvae were preserved for 7 or 26 days. Preservatives were 5% formalin, 10% formalin, 30% ethanol at -19 *C, 70% ethanol, and 90% ethanol. Preliminary average weights …

Healthy Aging Newsletter 2016 Special Issue On Men's Health, Paula J. Carter Center On Minority Health And Aging, Lincoln University Cooperative Extension

Paula J. Carter Center on Minority Health and Aging Newsletter

No abstract provided.

Academic Writing For Paramedics, Alan Batt

Faculty & Staff Publications - Public Safety

With the increasing move to higher education, being able to write an academic manuscript such as an essay or article has become a key skill required of paramedics and students world-wide. This guide aims to provide you with a brief explanation of one approach to academic writing.

From Higher Education To Work In West Virginia 2014, Eric Bowen, John Deskins, John Meszaros

Bureau of Business & Economic Research

No abstract provided.

Los Baños Times, Vol. 36, No. 1, College Of Development Communication, University Of The Philippines Los Baños

Los Baños Times

No abstract provided.

"But I Already Know All About Sex!" Distinguishing Beliefs From Empirical Facts When Teaching Sex, Gender, And Sexuality, Sarah Grison

Psychology Faculty

This slide presentation addresses teaching the biological aspects of human sexuality in psychology courses, and encourages instructors to create a safe environment to help student differentiate between beliefs and empirical facts about sexuality, sexual orientation, and gender identity. Encourages using visuals that help organize information and using real-world examples, providing examples of both.

Inherent Variability Of Cancer-Specific Aneuploidy Generates Metastases., Mathew Bloomfield, Peter Duesberg

Natural Sciences and Mathematics | Student Professional Publications

BACKGROUND: The genetic basis of metastasis is still unclear because metastases carry individual karyotypes and phenotypes, rather than consistent mutations, and are rare compared to conventional mutation. There is however correlative evidence that metastasis depends on cancer-specific aneuploidy, and that metastases are karyotypically related to parental cancers. Accordingly we propose that metastasis is a speciation event. This theory holds that cancer-specific aneuploidy varies the clonal karyotypes of cancers automatically by unbalancing thousands of genes, and that rare variants form new autonomous subspecies with metastatic or other non-parental phenotypes like drug-resistance - similar to conventional subspeciation.

RESULTS: To test this theory, …

Phylogenetic Relationships Of Dasyuromorphian Marsupials Revisited, Christopher A. Emerling, Michael Westerman, Carey Krajewski, Benjamin P. Kear, Lucy Meehan, Robert W. Meredith, Mark S. Springer

Biology

We reassessed the phylogenetic relationships of dasyuromorphians using a large molecular database comprising previously published and new sequences for both nuclear (nDNA) and mitochondrial (mtDNA) genes from the numbat (Myrmecobius fasciatus), most living species of Dasyuridae, and the recently extinct marsupial wolf, Thylacinus cynocephalus. Our molecular tree suggests that Thylacinidae is sister to Myrmecobiidae + Dasyuridae. We show robust support for the dasyurid intrafamilial classification proposed by Krajewski & Westerman as well as for placement of most dasyurid genera, which suggests substantial homoplasy amongst craniodental characters presently used to generate morphology-based taxonomies. Molecular dating with relaxed molecular clocks suggests that …

Inactivation Of Cone-Specific Phototransduction Genes In Rod Monochromatic Cetaceans, Christopher A. Emerling, Mark S. Springer, Noah Fugate, Rachna Patel, James Starrett, Phillip A. Morin, Cheryl Hayashi, John Gatesy

Biology

Vertebrate vision is mediated by two types of photoreceptors, rod and cone cells. Rods are more sensitive than cones in dim light, but are incapable of color discrimination because they possess only one type of photosensitive opsin protein (rod opsin = RH1). By contrast, cones are more important for vision in bright light. Cones also facilitate dichromatic color vision in most mammals because there are two cone pigment genes (SWS1, LWS) that facilitate color discrimination. Cone monochromacy occurs when one of the cone opsins (usually SWS1) is inactivated and is present in assorted subterranean, nocturnal, and aquatic mammals. Rod monochromacy …

Osteopontin Ablation Ameliorates Muscular Dystrophy By Shifting Macrophages To A Proregenerative Phenotype, Sylvia Vetrone, Joana Capote, Irina Kramerova, Leonel Martinez, Elisabeth R. Barton, H. Lee Sweeney, M. Carrie Miceli, Melissa J. Spencer

Biology

In the degenerative disease Duchenne muscular dystrophy, inflammatory cells enter muscles in response to repetitive muscle damage. Immune factors are required for muscle regeneration, but chronic inflammation creates a profibrotic milieu that exacerbates disease progression. Osteopontin (OPN) is an immunomodulator highly expressed in dystrophic muscles. Ablation of OPN correlates with reduced fibrosis and improved muscle strength as well as reduced natural killer T (NKT) cell counts. Here, we demonstrate that the improved dystrophic phenotype observed with OPN ablation does not result from reductions in NKT cells. OPN ablation skews macrophage polarization toward a pro-regenerative phenotype by reducing M1 and M2a …

The Role Of Open Lead Interactions In Atmospheric Ozone Variability Between Arctic Coastal And Inland Sites, Peter K. Peterson, Kerri A. Pratt, William R. Simpson, Son V. Nghiem, Lemuel X. Pérez Pérez, Eric J. Boone, Denis Pöhler, Johannes Zielcke, Stephan General, Paul B. Shepson, Udo Frieß, Ulrich Platt, Brian H. Stirm

Chemistry

Boundary layer atmospheric ozone depletion events (ODEs) are commonly observed across polar sea ice regions following polar sunrise. During March-April 2005 in Alaska, the coastal site of Barrow and inland site of Atqasuk experienced ODEs (O3 < 10 nmol mol-1) concurrently for 31% of the observations, consistent with large spatial scale ozone depletion. However, 7% of the time ODEs were exclusively observed inland at Atqasuk. This phenomenon also occurred during one of nine flights during the BRomine, Ozone, and Mercury EXperiment (BROMEX), when atmospheric vertical profiles at both sites showed near-surface ozone depletion only at Atqasuk on 28 March 2012. Concurrent in-flight BrO measurements made using nadir scanning differential optical absorption spectroscopy (DOAS) showed the differences in ozone vertical profiles at these two sites could not be attributed to differences in locally occurring halogen chemistry. During both studies, backward air mass trajectories showed that the Barrow air masses observed had interacted with open sea ice leads, causing increased vertical mixing and recovery of ozone at Barrow and not Atqasuk, where the air masses only interacted with tundra and consolidated sea ice. These observations suggest that, while it is typical for coastal and inland sites to have similar ozone conditions, open leads may cause heterogeneity in the chemical composition of the springtime Arctic boundary layer over coastal and inland areas adjacent to sea ice regions.

Southern Adventist University Graduate Catalog 2015-2016, Southern Adventist University

Catalog, Graduate

Southern Adventist University's graduate catalog for the academic year 2015-2016.

Southern Adventist University Graduate Catalog 2016-2017, Southern Adventist University

Catalog, Graduate

Southern Adventist University's graduate catalog for the academic year 2016-2017.

Honorary Degree Award Citation For Nicholas Maravolo, Lawrence University

Faculty Award Citations

No abstract provided.

Lawrence University Course Catalog, 2016-2017, Lawrence University

Course Catalogs

No abstract provided.

Southern Adventist University Undergraduate Catalog 2015-2016, Southern Adventist University

Catalog, Undergraduate

Southern Adventist University's undergraduate catalog for the academic year 2015-2016.

Southern Adventist University Undergraduate Catalog 2016-2017, Southern Adventist University

Catalog, Undergraduate

Southern Adventist University's undergraduate catalog for the academic year 2015-2016.

Southern Adventist University Undergraduate Handbook & Planner 2016-2017, Southern Adventist University

Student Handbooks, Undergraduate

No abstract provided.

Relative Growth Of Carcass Tissues Of Goat Kids From Five Breed Types Finished On Pasture Or Feedlot, Raquel Vasconcelos Lourençon, Heraldo Cesar Gonçalves, Paulo Roberto De Lima Meirelles, Richard Browning Jr., Maria Lenira Leite-Browning, Andréia Cristina Toniolo Chávari, Raquel Ornelas Marques, Gil Ignacio Lara Canizares, Natalia Santos Leal, Helen Fernanda Barros Gomes

Agricultural and Environmental Sciences Faculty Research

he aim of this study was to evaluate the effect of cross breeding, finishing system, and gender on the relative growth of carcass tissues of dairy kids. Seventy eight kids (39 male and 39 female) from five breed types were used: Alpine; ½ Boer + ½ Alpine (½ BA); ½ Nubian + ½ Alpine (½ ANA); ¾ Boer + ¼ Alpine (¾ BA); and ½ Nubian + ¼ Boer + ¼ Alpine (TC). Kids were distributed into two finishing systems: in pasture with doe (FS1) and weaned in feedlot (FS2). Kids were slaughtered at a mean age of 128.4 ± …

Shellfish And Seaweed Aquaculture As A Mechanism For Economic Diversification In Maine Island And Coastal Communities, Erin Love

Publications

Lobster is an iconic species in Maine, and for good reason. In 2015 80% of the landed value of commercially harvested Maine seafood was attributed to lobster. In a changing marine environment, the lobster fishery may not always be as robust as it is now. Shellfish and seaweed aquaculture is one possibility for marine harvesters looking to diversify away from lobster (or other species) in order to supplement their income or to foster an alternative source of income should their current fishery become unviable in the future. We used interview and questionnaire data from Casco Bay to Penobscot Bay to …

Metabolism And Metabolic Inhibition Of Xanthotoxol In Human Liver Microsomes, Zhongnv Ma, Xianbao Shi, Gang Zhang, Feng Guo, Lina Shan, Jiqun Cai

Medicinal Chemistry Publications

Cytochrome p450 (CYP450) enzymes are predominantly involved in Phase I metabolism of xenobiotics. In this study, the CYP450 isoforms involved in xanthotoxol metabolism were identified using recombinant CYP450s. In addition, the inhibitory effects of xanthotoxol on eight CYP450 isoforms and its pharmacokinetic parameters were determined using human liver microsomes. CYP1A2, one of CYP450s, played a key role in the metabolism of xanthotoxol compared to other CYP450s. Xanthotoxol showed stronger inhibition on CYP3A4 and CYP1A2 compared to other isoenzymes with the IC50 of 7.43 μM for CYP3A4 and 27.82 μM for CYP1A2. The values of inhibition kinetic parameters (Ki) were 21.15 …

Grunt Variation In The Oyster Toadfish Opsanus Tau: Effect Of Size And Sex, Michael L. Fine, Tyler D. Waybright

Biology Publications

As in insects, frogs and birds, vocal activity in fishes tends to be more developed in males than in females, and sonic swimbladder muscles may be sexually dimorphic, i.e., either larger in males or present only in males. Male oyster toadfish Opsanus tau L produce a long duration, tonal boatwhistle advertisement call, and both sexes grunt, a short duration more pulsatile agonistic call. Sonic muscles are present in both sexes but larger in males. We tested the hypothesis that males would call more than females by inducing grunts in toadfish of various sizes held in a net and determined incidence …

Repeated Low-Dose Organophosphate Dfp Exposure Leads To The Development Of Depression And Cognitive Impairment In A Rat Model Of Gulf War Illness, Laxmikant Deshpande, Kristin Phillips

Neurology Publications

Approximately 175,000 to 250,000 of the returning veterans from the 1991 Persian Gulf War exhibit chronic multi-symptom illnesses that includes neurologic co-morbidities such as depression, anxiety and cognitive impairments. Amongst a host of causative factors, exposure to low levels of the nerve agent Sarin has been strongly implicated for expression of Gulf War Illness (GWI). Nerve agents similar to pesticides are organophosphate (OP) compounds. There is evidence from civilian population that exposure to OPs such as in agricultural workers and nerve agents such as the survivors and first-responders of the Tokyo subway Sarin gas attack suffer from chronic neurological problems …

Planar Cell Polarity Genes Frizzled3a, Vangl2, And Scribble Are Required For Spinal Commissural Axon Guidance, Simon D. Sun, Ashley M. Purdy, Gregory S. Walsh

Biology Publications

Background

A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in order to assemble neural circuits that control behavior. Spinal commissural neurons are an attractive model to investigate the multiple guidance cues that control growth cone navigation both pre- and post-midline crossing, as well as along both the dorsal–ventral (D–V) and anterior–posterior (A–P) axes. Accumulating evidence suggests that guidance of spinal commissural axons along the A–P axis is dependent on components of the planar cell polarity (PCP) signaling pathway. In the zebrafish, the earliest born spinal commissural neuron to navigate the midline …

Different Vancomycin Immunoassays Contribute To The Variability In Vancomycin Trough Measurements In Neonates, Janko Samardzic, Anne Smits, Isabel Spriet, Ivan Soldatovic, Andrew Atkinson, Milica Bajcetic, John N. Van Den Anker, Karel Allegaert

Pediatrics Faculty Publications

Substantial interassay variability (up to 20%) has been described for vancomycin immunoassays in adults, but the impact of neonatal matrix is difficult to quantify because of blood volume constraints in neonates. However, we provide circumstantial evidence for a similar extent of variability. Using the same vancomycin dosing regimens and confirming similarity in clinical characteristics, vancomycin trough concentrations measured by PETINIA (2011-2012, n = 400) were 20% lower and the mean difference was 1.93 mg/L compared to COBAS (2012–2014, n =352 ) measurements. The impact of vancomycin immunoassays in neonatal matrix was hereby suggested, supporting a switch to more advanced techniques …

Recent Fast Food Consumption And Bisphenol A And Phthalates Exposures Among The U.S. Population In Nhanes, 2003-2010, Ami R. Zota, Cassandra Phillips, Susanna D. Mitro

Environmental and Occupational Health Faculty Publications

Background: Phthalates and bisphenol A (BPA) are widely used industrial chemicals that may adversely impact human health. Human exposure is ubiquitous and can occur through diet, including consumption of processed or packaged food.

Objective: To examine associations between recent fast food intake and BPA and urinary metabolites of di(2-ethylhexyl) phthalate (ΣDEHPm) and diisononyl phthalate (DiNPm) among the US population.

Methods: We combined data on 8877 participants from the National Health and Nutrition Examination Survey (NHANES 2003-2010). Using 24-hour dietary recall data, we quantified: 1) fast food intake (percent of total energy intake (TEI) from fast food); 2) fast food-derived fat …

Cryptosporidium Priming Is More Effective Than Vaccine For Protection Against Cryptosporidiosis In A Murine Protein Malnutrition Model, Luther A. Bartelt, David T. Bolick, Glynis L. Kolling, James K. Roche, Edna I. Zaenker, Ana M. Lara, Francisco Jose Noronha, Carrie A. Cowardin, John H. Moore, Jerrold R. Turner, Cirle A. Warren, Gregory A. Buck, Richard L. Guerrant

Biochemistry and Molecular Biology Publications

Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the effect of protein malnutrition (PM) on primary and secondary responses to C. parvum challenge, and tested the differential ability of mucosal priming strategies to overcome the PM-induced susceptibility. We determined that while PM fundamentally alters systemic and mucosal primary immune responses to Cryptosporidium, priming with C. parvum (106 oocysts) provides robust protective immunity against re-challenge despite ongoing PM. C. parvum priming restores mucosal Th1-type effectors (CD3+CD8+CD103+ T-cells) …

Constitutive Association Of Tie1 And Tie2 With Endothelial Integrins Is Functionally Modulated By Angiopoietin-1 And Fibronectin, Annamarie C. Dalton, Tomer Shlamkovitch, Niv Papo, William A. Barton

Biochemistry and Molecular Biology Publications

Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the extracellular matrix, yet the mechanisms behind this phenomenon are unclear. Here, we examine the possibility that receptor cross-talk is driven through uncharacterized Tie-integrin interactions on the endothelial surface. Using a live cell FRET-based proximity assay, we monitor Tie-integrin receptor recognition and demonstrate that both Tie1 and Tie2 readily associate with integrins α5ß1 and αVß3 through their respective ectodomains. Although not required, Tie2-integrin association is significantly enhanced in the presence of the extracellular component and integrin ligand fibronectin. In vitro …

Characterization Of Current And Historical Variations In Sediment Accretion And Carbon Dynamics At The Rice Rivers Center Kimages Creek Wetland Restoration, Melissa J. Davis, Christopher D. Gatens, Edward R. Crawford, Arif Sikder

Rice Rivers Center Research Symposium

Current research of freshwater wetland soils have assessed and reported smaller stocks of soil organic carbon in restored wetlands compared to reference natural wetlands. However, a majority of these studies focus on sites restored from agricultural draining of non-tidal depressional wetlands,whereas carbon and accretion dynamics in tidal freshwater wetlands restored via dam removal is poorly understood. The U.S. Army Corps of Engineers estimates over 80,000 dams greater than 6 feet and tens of thousands of smaller dams pepper the U.S., of which the majority are unsafe, old or no longer serve their intended purpose. Damming disrupts the natural flow of …