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Displacement, Identity And Belonging For Ibyangin: The Personal Journey Of Transracial Korean-Born Adoptees, Jason D. Reynolds, Joseph G. Ponterotto, Christina Lecker

The Qualitative Report

The present study examined the lived experience (erlebnis) of adult transracial, Korean-born adoptees (Ibyangin; Yngvesson & Coutin, 2006) raised in the United States by White families. Long interviews (McCracken, 1988) were conducted with fourteen young adult (age 26-30) Korean-born adoptees in-person or by phone. The study was anchored in the constructivist-interpretivist research paradigm (Ponterotto, 2005) and utilized the phenomenological inquiry model (Moustakas, 1994) to explore the essence of the international transracial adoption experience. Two major clusters of meaning with additional subthemes were related to a) identity development, and b) decision to return to Korea. Limitations of the study are reviewed, …

Credits Earned, Credits Due: Forging New Degree Completion Pathways For Post-Traditional Students With The Aid Of Prior Learning Assessment Portfolios, Patrick Guilbaud, Greg Oakes

Winthrop Conference on Teaching and Learning

In recent years, there has been a surge in the number of adult students who have expressed interest in returning back to school to complete their undergraduate degrees. Research, however, shows that many adult students who start degree completion programs do not complete them.

An oft-cited roadblock to degree completion by adult students is lack of recognition of prior learning obtained on the job or through other means. As a result, prior learning assessment (PLA) has now become an important tool used by colleges and universities to facilitate access to higher education by adult students.

The Council for Adult & …

Bioinformatics Comparison Of M. Ruber Mrub_2507 To E. Coli Pdxk/B1636 And M. Ruber Mrub_2888 To E. Coli Pdxh/B1638 To Determine The Orthologous Nature, Adam Bernardi, Dr. Lori Scott

Meiothermus ruber Genome Analysis Project

This project is part of the Meiothermus ruber genome analysis project, which uses the bioinformatics tools associated with the Guiding Education through Novel Investigation – Annotation Collaboration Toolkit (GENI-ACT) to predict gene function. We investigated the biological function of the genes Mrub_2507 and Mrub_2888. We predict that Mrub_2507 encodes the enzyme pyridoxal kinase (DNA coordinates 2555521..2556402), which is in the Vitamin B₆ Metabolism pathway (KEGG map number 00750). It catalyzes the conversion of pyridoxine, pyridoxamine, or pyridoxal to pyridoxine 5’-phosphate, pyridoxamine 5’-phosphate, or pyridoxal 5’-phosphate respectively. The E. coli K12 MG1655 ortholog is predicted to be b1636, which has …

Therapeutic Effect Of Melatonin On Pediatric Functional Dyspepsia: A Pilot Study., Katherine Zybach, Craig A. Friesen, Jennifer V. Schurman

Manuscripts, Articles, Book Chapters and Other Papers

AIM: To study the effectiveness of melatonin vs placebo in children with functional dyspepsia (FD).

METHODS: The study was conducted as a double blind, randomized, placebo controlled crossover trial. Subjects were aged 8-17 years and diagnosed with FD based on Rome III criteria. All subjects had failed to respond to 4 wk of acid suppression. Subjects receive a continuous two weeks of placebo and a continuous two weeks of melatonin in an order blinded to the participant and the study team. A Global Clinical Score was obtained to assess changes in abdominal pain. Pain was self-reported to be worse (grade …

The Hidden Under Caste Of America: An Examination Of The Effects Of Terry V. Ohio, Florida V. Bostick, & Whren V. United States And Colorblindness On African Americans, Austin Schoeck

Political Science: Student Scholarship & Creative Works

No abstract provided.

Ab Blood Type And Its Genetic Relationship To Alzheimer’S Disease, Mark Wadsworth, John S. K. Kauwe

Journal of Undergraduate Research

Alzheimer’s Disease (AD) is a debilitating disease that has increased the hardship of many lives. Many people above the age of 65 have been diagnosed with this genetically complex disease, which financially and emotionally burdens those diagnosed and their families. Earlier this year a study was released that found, using a dataset of individuals that have had strokes, that individuals with AB blood type are more at risk of developing cognitive impairment[1]. This study however was not looking at the genetics of AD. My objective in performing this study was to see if there is a genetic association between Alzheimer’s …

Spring Convocation 2016 Program, Office For The Vice President Of Research

Spring Convocation

Program of the first Spring Convocation: Recognition of Discovery, Diversity and Global Engagement held Feb 5, 2016 at the Fetzer Center at Western Michigan University.

Determining If C-Fos Protects Β-Cells From Apoptosis, Kyle Kener, Jeffery Tessem

Journal of Undergraduate Research

Diabetes, a disease characterized by the inability of the body to maintain a normal blood glucose level, continues to affect the lives of many. In both Type I and Type II diabetes, eventual β-cell destruction results in decreased β-cell mass. Regeneration of functional β-cells and protection of such, could help reverse the effects of this disease and could possibly lead to a cure. Many studies have been done to increase functioning β-cell mass, but protecting regenerated β-cells from further apoptotic insults could greatly increase the effectiveness of β-cell transplants and other future treatments of the disease.

Role Of Serum Biomarkers In Early Detection Of Diabetic Cardiomyopathy In The West Virginian Population, Adam Shaver, Alexandra Nichols, Ellen A. Thompson, Amrita Mallick, Nandini Manne, Shanmuga Sundaram, Joseph I. Shapiro Md, Komal Sodhi

Biochemistry and Microbiology

Objectives: Diabetic cardiomyopathy (DCM) is an established complication of diabetes mellitus. In West Virginia, the especially high incidence of diabetes and heart failure validate the necessity of developing new strategies for earlier detection of DCM. Since most DCM patients remain asymptomatic until the later stages of the disease when the fibrotic complications become irreversible, we aimed to explore biomarkers that can identify early-stage DCM.

Methods: The patients were grouped into 4 categories based on clinical diabetic and cardiac parameters: Control, Diabetes (DM), Diastolic dysfunction (DD), and Diabetes with diastolic dysfunction (DM+DD), the last group being the preclinical DCM group.

Results: …

K. R.G. V. Secretary Of Health And Human

2016 Decisions

USDC for the Eastern District of Pennsylvania

Insight Into The Potential Factors That Promote Tobacco Use In Vulnerable Populations, Laura O'Dell, Luis Carcoba, Oscar Torres, Joseph Pipkin, Tiahna Ontiveros

Departmental Papers (Psych)

No abstract provided.

Targeting An Essential Gtpase Obg For The Development Of Broad-Spectrum Antibiotics, Josephine A. Bonventre, Ryszard A. Zielke, Konstantin V. Korotkov, Aleksandra E. Sikora

Molecular and Cellular Biochemistry Faculty Publications

A promising new drug target for the development of novel broad-spectrum antibiotics is the highly conserved small GTPase Obg (YhbZ, CgtA), a protein essential for the survival of all bacteria including Neisseria gonorrhoeae (GC). GC is the agent of gonorrhea, a prevalent sexually transmitted disease resulting in serious consequences on reproductive and neonatal health. A preventive anti-gonorrhea vaccine does not exist, and options for effective antibiotic treatments are increasingly limited. To address the dire need for alternative antimicrobial strategies, we have designed and optimized a 384-well GTPase assay to identify inhibitors of Obg using as a model Obg protein from …

Ungulate Reproductive Parameters Track Satellite Observations Of Plant Phenology Across Latitude And Climatological Regimes, David C. Stoner, Joseph O. Sexton, Jyoteshwar Nagol, Heather H. Bernales, Thomas C. Edwards Jr.

Wildland Resources Faculty Publications

The effect of climatically-driven plant phenology on mammalian reproduction is one key to predicting species-specific demographic responses to climate change. Large ungulates face their greatest energetic demands from the later stages of pregnancy through weaning, and so in seasonal environments parturition dates should match periods of high primary productivity. Interannual variation in weather influences the quality and timing of forage availability, which can influence neonatal survival. Here, we evaluated macro-scale patterns in reproductive performance of a widely distributed ungulate (mule deer, Odocoileus hemionus) across contrasting climatological regimes using satellite-derived indices of primary productivity and plant phenology over eight degrees of …

Frans De Waal Named Recipient Of 2016 Ireland Distinguished Visiting Scholar Award, Staff

Browse All News

No abstract provided.

Um Recognized Among Country's Elite Research Universities, Edwin Smith

University of Mississippi News

Carnegie Classification recognizes R&D investment, doctoral degrees granted and faculty achievement

2016-February-05, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Emu Today, February 5, 2016, Eastern Michigan University

EMU Today

No abstract provided.

The Two-Component System Cpxra Negatively Regulates The Locus Of Enterocyte Effacement Of Enterohemorrhagic Escherichia Coli Involving Σ32 And Lon Protease, Miguel A. De La Cruz, Jason K. Morgan, Miguel A. Ares, Jorge A. Yáñez-Santos, James T. Riordan, Jorge A. Girón

Molecular Biosciences Faculty Publications

Enterohemorrhagic Escherichia coli (EHEC) is a significant cause of serious human gastrointestinal disease worldwide. EHEC strains contain a pathogenicity island called the locus of enterocyte effacement (LEE), which encodes virulence factors responsible for damaging the gut mucosa. The Cpx envelope stress response of E. coli is controlled by a two-component system (TCS) consisting of a sensor histidine kinase (CpxA) and a cytoplasmic response regulator (CpxR). In this study, we investigated the role of CpxRA in the expression of LEE-encoded virulence factors of EHEC. We found that a mutation in cpxA significantly affected adherence of EHEC to human epithelial cells. Analysis …

Temporal Control Of Gelation And Polymerization Fronts Driven By An Autocatalytic Enzyme Reaction, Elizabeth Jee, Tamás Bánsági, Annette F. Taylor, John A. Pojman

Faculty Publications

© 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. Chemical systems that remain kinetically dormant until activated have numerous applications in materials science. Herein we present a method for the control of gelation that exploits an inbuilt switch: the increase in pH after an induction period in the urease-catalyzed hydrolysis of urea was used to trigger the base-catalyzed Michael addition of a water-soluble trithiol to a polyethylene glycol diacrylate. The time to gelation (minutes to hours) was either preset through the initial concentrations or the reaction was initiated locally by a base, thus resulting in polymerization fronts …

Age Related Decline In Female Lar Gibbon Great Call Performance Suggests That Call Features Correlate With Physical Condition, Thomas A. Terlepht, Suchinda Malaivijitnond, Ulrich H. Reichard

Publications

Background: White-handed gibbons (Hylobates lar) are small Asian apes known for living in stable territories and producing loud, elaborate vocalizations (songs), often in well-coordinated male/female duets. The female great call, the most conspicuous phrase of the repertoire, has been hypothesized to function in intra-sexual territorial defense. We therefore predicted that characteristics of the great call would correlate with a caller’s physical condition, and thus might honestly reflect resource holding potential (RHP). Because measurement of RHP is virtually impossible for wild animals, we used age as a proxy, hypothesizing that great call climaxes are difficult to produce and maintain over time, …

Daily Eastern News: Feburary 05, 2016, Eastern Illinois University

February

No abstract provided.

Using A Functional Language Approach To Engage High School English Language Learners In Academic Language Arts Content, Robert Grant Schaller

School of Education and Leadership Student Capstone Theses and Dissertations

The research question addressed in this capstone project was; how can a curriculum, rooted in the experiential metafunction of functional language analysis, be developed to help secondary English language learners gain academic language needed in a language arts classroom? It looks at the struggle high school ELLs face because of the academic language used in content classes. It also looks at the components of functional language analysis and how they can be used to teach the academic language needed for student success. The author utilized the work of Christie, F. (2012), Fang, Z., & Schleppegrell, M. J. (2008), and Martin, …

Stable Isotope Resolved Metabolomics Studies In Ex Vivo Tissue Slices, Teresa W-M Fan, Andrew N. Lane, Richard M. Higashi

Toxicology and Cancer Biology Faculty Publications

An important component of this methodology is to assess the role of the tumor microenvironment on tumor growth and survival. To tackle this problem, we have adapted the original approach of Warburg (Warburg, 1923), by combining thin tissue slices with Stable Isotope Resolved Metabolomics (SIRM) to determine detailed metabolic activity of human tissues. SIRM enables the tracing of metabolic transformations of source molecules such as glucose or glutamine over defined time periods, and is a requirement for detailed pathway tracing and flux analysis. In our approach, we maintain freshly resected tissue slices (both cancerous and non- cancerous from the same …

The Significance Of A Common Idiotype (1f7) On Antibodies Against Human Immune Deficiency Virus Type 1 And Hepatitis C Virus, Sybille Muller, Matthew S. Parsons, Heinz Kohler, Michael Grant

Microbiology, Immunology, and Molecular Genetics Faculty Publications

In this review, we trace the concept and potential functional role of regulatory idiotypes in the immune response to human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and hepatitis C virus (HCV). A major idiotype involved in these viral infections is recognized and defined by a murine monoclonal antibody (1F7). Antibodies expressing the idiotype defined by 1F7 are dominant in HIV-1 infection and are also found on many broadly neutralizing antibodies against HIV-1. This regulatory idiotypic axis offers opportunities for exploitation in vaccine development for HIV-1, HCV, and other chronic viral infections.

Blockage Of The Ryanodine Receptor Via Azumolene Does Not Prevent Mechanical Ventilation-Induced Diaphragm Atrophy, Erin E. Talbert, Ashley J. Smuder, Oh Sung Kwon, Kurt J. Sollanek, Michael P. Wiggs, Scott K. Powers

Health & Kinesiology Faculty Publications and Presentations

Mechanical ventilation (MV) is a life-saving intervention for patients in respiratory failure. However, prolonged MV causes the rapid development of diaphragm muscle atrophy, and diaphragmatic weakness may contribute to difficult weaning from MV. Therefore, developing a therapeutic countermeasure to protect against MV-induced diaphragmatic atrophy is important. MV-induced diaphragm atrophy is due, at least in part, to increased production of reactive oxygen species (ROS) from diaphragm mitochondria and the activation of key muscle proteases (i.e., calpain and caspase-3). In this regard, leakage of calcium through the ryanodine receptor (RyR1) in diaphragm muscle fibers during MV could result in increased mitochondrial ROS …

Taylor’S Power Law And The Statistical Modelling Of Infectious Disease Surveillance Data, Dg Enki, A Noufaily, P Farrington, P Garthwaite, N Andrews

School of Engineering, Computing and Mathematics

Surveillance data collected on several hundred different infectious organisms over 20 years have revealed striking power relationships between their variance and mean in successive time periods. Such patterns are common in ecology, where they are referred to collectively as Taylor's power law. In the paper, these relationships are investigated in detail, with the aim of exploiting them for the descriptive statistical modelling of infectious disease surveillance data. We confirm the existence of variance-to-mean power relationships, with exponent typically between 1 and 2. We investigate skewness-to-mean relationships, which are found broadly to match those expected of Tweedie distributions, and thus confirm …

2016-February-05-Darwin Day, University Marketing And Communications, Est Tennessee State University

ETSU News

No abstract provided.

Comparing Apples And Oranges?: Next Generation Sequencing And Its Impact On Microbiome Analysis, Adam G. Clooney, Fiona Fouhy, Roy D. Sleator, Aisling O'Driscoll, Stanton Catherine, Paul D. Cotter, Marcus J. Claesson

Department of Biological Sciences Publications

Rapid advancements in sequencing technologies along with falling costs present widespread opportunities for microbiome studies across a vast and diverse array of environments. These impressive technological developments have been accompanied by a considerable growth in the number of methodological variables, including sampling, storage, DNA extraction, primer pairs, sequencing technology, chemistry version, read length, insert size, and analysis pipelines, amongst others. This increase in variability threatens to compromise both the reproducibility and the comparability of studies conducted. Here we perform the first reported study comparing both amplicon and shotgun sequencing for the three leading next-generation sequencing technologies. These were applied to …

Comparing Apples And Oranges?: Next Generation Sequencing And Its Impact On Microbiome Analysis, Roy D. Sleator, Aisling O'Driscoll, Et. Al.

Department of Biological Sciences Publications

Rapid advancements in sequencing technologies along with falling costs present widespread opportunities for microbiome studies across a vast and diverse array of environments. These impressive technological developments have been accompanied by a considerable growth in the number of methodological variables, including sampling, storage, DNA extraction, primer pairs, sequencing technology, chemistry version, read length, insert size, and analysis pipelines, amongst others. This increase in variability threatens to compromise both the reproducibility and the comparability of studies conducted. Here we perform the first reported study comparing both amplicon and shotgun sequencing for the three leading next-generation sequencing technologies. These were applied to …

Discovery And Characterization Of Bacteriophage To Control Mrsa, Jacob B. Hatch, Bradford Berges

Journal of Undergraduate Research

About 20% of humans are carriers of Staphylococcus aureus (SA). There were an estimated 11,000 deaths in the United States in 2005 attributed to SA, with the majority caused by MRSA (Methicillin Resistant Staphylococcus Aureus) isolates [1]. Many MRSA isolates have developed resistance to all but one antibiotic drug: vancomycin. However, other bacteria have developed resistance to vancomycin, suggesting that in time MRSA will likewise become non-responsive to this last available drug and MRSA infections will be untreatable. This project looks to find an alternate method of MRSA treatment. Bacteriophage (phage) are viruses that infect bacterial cells in order …