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2016

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Phylogenetic Relationships Of Cottids (Pisces: Cottidae) In Upper Snake River Basin Of Western North America, Sun Yeong Oh Mar 2016

Phylogenetic Relationships Of Cottids (Pisces: Cottidae) In Upper Snake River Basin Of Western North America, Sun Yeong Oh

Theses and Dissertations

Freshwater sculpins (Cottus) are common throughout temperate regions of the Northern Hemisphere. Their broad distribution in the Western North America makes them a good model for understanding phylogeographic relationships among western fishes. Within much of the interior west three lineages, C. bairdii, C. confusus, and the C. beldingii complex, are most prevalent. The distribution of these three overlap in the Snake River Basin. All occur below Shoshone Falls on the Snake River. However, only two currently reside in the Upper Snake River above the falls. An exception are the Lost River streams of central Idaho. While …


Manfred, Don Juan, And The Romantic Tragedy Of The Subject, Trenton Robert Leinenbach Mar 2016

Manfred, Don Juan, And The Romantic Tragedy Of The Subject, Trenton Robert Leinenbach

Theses and Dissertations

While the Romantic lyric has long been understood as an exploration of human subjectivity, the era's dramatic works have been viewed as more oriented toward objective or mimetic representation. As such, scholarship on Romantic subjectivity from Harold Bloom to Andrea Henderson has bypassed dramatic and quasi-dramatic explorations of subjectivity. These explorations, however, add to the conversation about subjectivity in powerful ways by addressing the paradoxes of mimetically representing subjectivity. These difficulties spring from a question that surrounds mimetically represented subjectivity: how can a supposedly objective medium portray experience that is by definition non-objective, purely interior, and therefore incommunicable? This paradox …


Forward Chemical Genetics Drug Screen Yields Novel Proteases And Proteolytic Inhibitors Of Hgf–Induced Epithelial–Mesenchymal Transition, Jeffrey Thomas Schuler Mar 2016

Forward Chemical Genetics Drug Screen Yields Novel Proteases And Proteolytic Inhibitors Of Hgf–Induced Epithelial–Mesenchymal Transition, Jeffrey Thomas Schuler

Theses and Dissertations

Hepatocyte Growth Factor (HGF)–induced Epithelial–Mesenchymal Transition (EMT) is a complex cellular pathway that causes epithelial cell scattering by breaking cell–cell contacts, eliminating apical–basal polarity, and replacing epithelial markers and characteristics with mesenchymal markers. Early EMT events include a brief period of cell spreading, followed by cell compaction and cell–cell contact breaks. A forward chemical genetics drug screen of 50,000 unique compounds measuring HGF–induced cell scattering identified 26 novel EMT inhibitors, including 2 proteolytic inhibitors. Here, we show that B5500–4, one of the EMT inhibitors from the screen, blocks HGF–induced EMT by a predicted blocking of the protease furin, in addition …


The Bg News March 01, 2016, Bowling Green State University Mar 2016

The Bg News March 01, 2016, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 01, 2016. Volume 95-Issue 48.


Immunization Status Of Nicu Graduates At A Tertiary Care Children's Hospital, Leslie Jane Huggins Mar 2016

Immunization Status Of Nicu Graduates At A Tertiary Care Children's Hospital, Leslie Jane Huggins

Theses and Dissertations

The objectives of this study were to determine the current rates of immunization and identify variables associated with immunizations of NICU graduates who were 60 days of age or older at time of discharge. This is a descriptive pilot study utilizing retrospective paper chart review. The relationships between immunization status and study variables were examined using logistic regression. Of 43 infants discharged at least 60 days of age or older from the NICU, 74.4% were up to date for immunizations in accordance with AAP recommendations. Additional variables were not significant. Immunization needs to be a priority in order to give …


Resilience And Internalizing Symptoms Among Adolescent Girls In Residential Treatment: An Evaluation Of Strong Teens, Luke Andrew Marvin Mar 2016

Resilience And Internalizing Symptoms Among Adolescent Girls In Residential Treatment: An Evaluation Of Strong Teens, Luke Andrew Marvin

Theses and Dissertations

Strong Teens is an evidence-based social and emotional learning (SEL) curriculum designed to target internalizing disorders by promoting emotional resilience and social competence. In this study, Strong Teens was implemented among 36 adolescent girls during group therapy in a residential treatment center (RTC). A non-equivalent, quasi-experimental wait-list control group design was used. The curriculum was evaluated by tracking the girls' social and emotional knowledge, internalizing symptoms, and resilience from the perspectives of the girls, group therapists, and a supervisor who was blind to the study. Although the results indicated that exposure to Strong Teens was not effective in increasing the …


Revisiting The Past: Review Of Central Council For Research In Homoeopathy Quarterly Bulletin Volume 17 (1-4) 1995, Deepti Chalia Mar 2016

Revisiting The Past: Review Of Central Council For Research In Homoeopathy Quarterly Bulletin Volume 17 (1-4) 1995, Deepti Chalia

Indian Journal of Research in Homoeopathy

No abstract provided.


Effective Rheological Properties In Semi-Dilute Bacterial Suspensions, Mykhailo Potomkin, Shawn D. Ryan, Leonid Berlyand Mar 2016

Effective Rheological Properties In Semi-Dilute Bacterial Suspensions, Mykhailo Potomkin, Shawn D. Ryan, Leonid Berlyand

Mathematics and Statistics Faculty Publications

Interactions between swimming bacteria have led to remarkable experimentally observable macroscopic properties such as the reduction in the effective viscosity, enhanced mixing, and diffusion. In this work, we study an individual-based model for a suspension of interacting point dipoles representing bacteria in order to gain greater insight into the physical mechanisms responsible for the drastic reduction in the effective viscosity. In particular, asymptotic analysis is carried out on the corresponding kinetic equation governing the distribution of bacteria orientations. This allows one to derive an explicit asymptotic formula for the effective viscosity of the bacterial suspension in the limit of bacterium …


Chronic Drinking During Adolescence Predisposes The Adult Rat For Continued Heavy Drinking: Neurotrophin And Behavioral Adaptation After Long-Term, Continuous Ethanol Exposure, Gina M. Fernandez, William N. Stewart, Lisa M. Savage Mar 2016

Chronic Drinking During Adolescence Predisposes The Adult Rat For Continued Heavy Drinking: Neurotrophin And Behavioral Adaptation After Long-Term, Continuous Ethanol Exposure, Gina M. Fernandez, William N. Stewart, Lisa M. Savage

Psychology Faculty Scholarship

Previous research has found that adolescent ethanol (EtOH) exposure alters drug seeking behaviors, cognition and neuroplasticity. Using male Sprague Dawley rats, differences in spatial working memory, non-spatial discrimination learning and behavioral flexibility were explored as a function of age at the onset (mid-adolescent vs. adult) of chronic EtOH exposure (CET). Concentrations of mature brain-derived neurotrophic factor (mBDNF) and betanerve growth factor (beta-NGF) in the prefrontal cortex and hippocampus were also assessed at different time-points: during CET, following acute abstinence (48-hrs), and after protracted abstinence (6-8 wks). Our results revealed that an adolescent onset of CET leads to increased EtOH consumption …


The Update, March-May 2016, University Of Northern Iowa. College Of Humanities, Arts And Sciences. Mar 2016

The Update, March-May 2016, University Of Northern Iowa. College Of Humanities, Arts And Sciences.

Update

Inside This Issue:
--CHAS Briefs
--Spotlight– Alumni Katy Slaven
--Spotlight – Faculty Dr. Rui He
--School of Music Women's Choir Tours Ireland
--Spotlight – Student Cassara Higgins
--Featured Story: ECO+House Art Exhibition
--Communication Sciences & Disorders
--ICCD Conference
--Spotlight – Student Bob Spielbauer
--Spotlight – Student Lisa Diercks


Cracks In The Cornerstone: Toward More Informed Decision-Making In Rhetorical Education, David M. Grant Mar 2016

Cracks In The Cornerstone: Toward More Informed Decision-Making In Rhetorical Education, David M. Grant

UNIversitas: Journal of Research, Scholarship, and Creative Activity

In their forum on the First-Year Cornerstone course, April Chatham-Carpenter and Deedee Heistad (2015) explain their memories of developing the program and sketch a vision of what they hope they have achieved. Certainly, all involved have worked "toward the goal of helping first-year students succeed in college," and they should be commended for their dedication and efforts to bring together often disconnected parts of the university in the name of improving student learning, retention, and overall satisfaction. As an early member of the planning team who assisted bringing the proposal for Cornerstone to the Liberal Arts Core Committee in 2010 …


Nigella Sativa And Its Active Constituent Thymoquinone In Oral Health, Safia A. Alattas, Fat’Heya M. Zahran, Shereen A. Turkistany Mar 2016

Nigella Sativa And Its Active Constituent Thymoquinone In Oral Health, Safia A. Alattas, Fat’Heya M. Zahran, Shereen A. Turkistany

Saudi Medical Journal

In this review, we summarized published reports that investigated the role of Nigella sativa (NS) and its active constituent, thymoquinone (TQ) in oral health and disease management. The literature studies were preliminary and scanty, but the results revealed that black seed plants have a potential therapeutic effect for oral and dental diseases. Such results are encouraging for the incorporation of these plants in dental therapeutics and hygiene products. However, further detailed preclinical and clinical studies at the cellular and molecular levels are required to investigate the mechanisms of action of NS and its constituents, particularly TQ.


Occurrence And Antibacterial Susceptibility Pattern Of Bacterial Pathogens Isolated From Diarrheal Patients In Pakistan, Muhammad H. Rasool, Abu B. Siddique, Muhammad Saqalein, Muhammad J. Asghar, Muhammad A. Zahoor, Bilal Aslam, Humerah B. Shafiq, Muhammad A. Nisar Mar 2016

Occurrence And Antibacterial Susceptibility Pattern Of Bacterial Pathogens Isolated From Diarrheal Patients In Pakistan, Muhammad H. Rasool, Abu B. Siddique, Muhammad Saqalein, Muhammad J. Asghar, Muhammad A. Zahoor, Bilal Aslam, Humerah B. Shafiq, Muhammad A. Nisar

Saudi Medical Journal

Objective: To determine the occurrence of bacterial pathogens responsible for diarrhea and to engender information regarding the effectiveness of commonly used antibiotic against diarrhea. Methods: This cross-sectional study was conducted between April and July 2014. Samples were collected from the Divisional Headquarter and Allied Hospital, Faisalabad, Pakistan. The differential and selective media were used to isolate bacterial pathogens, which were identified through cultural characteristics, microscopy, and biochemical tests. Disc diffusion assay was carried out using Muller Hinton agar medium, and minimum inhibitory concentration was determined using broth dilution method against isolated pathogens. Results: One hundred and forty-one (100%) samples were …


Laparoscopic Repair Of Diaphragm Perforation With Heart Patch After Microwave Ablation, Qing-Chen Liang, Yan-Jie Tian, Ting Xiao-Jiang Mar 2016

Laparoscopic Repair Of Diaphragm Perforation With Heart Patch After Microwave Ablation, Qing-Chen Liang, Yan-Jie Tian, Ting Xiao-Jiang

Saudi Medical Journal

Microwave ablation (MWA) is a new technology developed in recent years, which is widely used in various disciplines. Microwave ablation is an alternative to surgery in the management of various tumors, and it has been demonstrated to be effective in the management of primary tumors and metastatic tumors. Microwave ablation is widely used in the treatment of hepatocellular carcinoma with an obvious effect and less side effects, and only 2.7% had serious complications. Many studies have confirmed the complications are thermal damage, hemorrhage, pleural effusion, bile leak, tumor seeding, hepatic abscess, cholangitis, and so forth. But diaphragm perforation is rare, …


Virtual Schools In Tennessee, Tennessee. Comptroller Of The Treasury. Mar 2016

Virtual Schools In Tennessee, Tennessee. Comptroller Of The Treasury.

Office of Research and Education Accountability

No abstract provided.


Techniques And Approaches To Genetic Analyses In Nephrological Disorders., Laurel K. Willig Mar 2016

Techniques And Approaches To Genetic Analyses In Nephrological Disorders., Laurel K. Willig

Manuscripts, Articles, Book Chapters and Other Papers

Inherited renal disease is a leading cause of morbidity and mortality in pediatric nephrology. High throughput advancements in genomics have led to greater understanding of the biologic underpinnings of these diseases. However, the underlying genetic changes explain only part of the molecular biology that contributes to disease manifestation and progression. Other omics technologies will provide a more complete picture of these cellular processes. This review discusses these omics technologies in the context of pediatric renal disease.


Editorial: Glial Cells: Managers Of Neuro-Immunity, Carlos Barcia, Gilles Guillemin, James Curtin, Jeffrey Zirger Mar 2016

Editorial: Glial Cells: Managers Of Neuro-Immunity, Carlos Barcia, Gilles Guillemin, James Curtin, Jeffrey Zirger

Articles

No abstract provided.


The Opposite Of Anarchy And The Transmission Of Faith: The Freedom To Teach After Smith, Hosanna-Tabor, Obergefell, And The Ascendancy Of Sexual Expressionism, Helen M. Alvaré Mar 2016

The Opposite Of Anarchy And The Transmission Of Faith: The Freedom To Teach After Smith, Hosanna-Tabor, Obergefell, And The Ascendancy Of Sexual Expressionism, Helen M. Alvaré

San Diego Law Review

There are several avenues available for protecting religious schools’ freedom but none involving rote application of the summary holdings of Smith or Hosanna-Tabor. This shouldn’t surprise; little is simple where the religion clauses are concerned. Nevertheless, to provide free exercise and nonestablishment “on the ground” and to allow core tenets of Judeo-Christian traditions a genuine, not just theoretical, chance of reaching the next generation, the Supreme Court needs to find a way within the labyrinth of its current First Amendment jurisprudence to allow religious schools and parents the freedom to teach.

This Article will treat this question as follows. Part …


Sexualization, Sex Discrimination, And Public School Dress Codes, Meredith Johnson Harbach Mar 2016

Sexualization, Sex Discrimination, And Public School Dress Codes, Meredith Johnson Harbach

University of Richmond Law Review

This essay joins the conversation about sexualization, sex discrimination, and public school dress codes to situate current debates within in the broader cultural and legal landscapes in which they exist. My aim is not to answer definitively the questions I pose above. Rather, I ground the controversy in these broader contexts in order to better understand the stakes and to glean insights into how schools, students, and communities might better navigate dress code debates.


Ms171: Interview With Marianne Marcus, Marianne Marcus Edd, Rn, Houston Academy Of Medicine-Texas Medical Center Library Mar 2016

Ms171: Interview With Marianne Marcus, Marianne Marcus Edd, Rn, Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral history with Marianne Marcus, Professor Emerita at the University of Texas at Houston School of Nursing. Before she retired and assumed the title of Professor Emerita in 2104, Dr. Marcus chaired the UT Nursing School’s Department of Nursing Systems, directed its Master’s of Nursing Education degree track and directed its Center for Substance Abuse Prevention, Education and Research. While at UT, she was elected to its Academy of Health Science Education and named as a Fellow of the American Academy of Nursing. She was appointed the John P. McGovern Distinguished Professor of Addiction Nursing at UT Health Science …


Ms171: Interview With Huda Zoghbi, Huda Zoghbi Md, Houston Academy Of Medicine-Texas Medical Center Library Mar 2016

Ms171: Interview With Huda Zoghbi, Huda Zoghbi Md, Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral history interview with Dr. Huda Zoghbi about her career at Baylor College of Medicine in the Texas Medical Center. She worked as a professor in the Departments of Pediatrics, Molecular and Human Genetics, Neurology and Neuroscience at Baylor College of Medicine. She was also an investigator at the Howard Hughes Medical Institute and the director of the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital. See more at Texas Medical Center-Women's History Project and its finding aid.

SOURCE: Baylor College of Medicine website, http://www.bcm.edu


Ms171: Interview With Margaret Caddy, Margaret Caddy, Houston Academy Of Medicine-Texas Medical Center Library Mar 2016

Ms171: Interview With Margaret Caddy, Margaret Caddy, Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral History interview with Margaret Caddy discussing her nursing and administrative career in Houston and the Texas Medical Center. Caddy worked in hospice care from 1983-2009. Part of that time, She served as the Executive Director for Houston Hospice. See more at Texas Medical Center-Women's History Project and its finding aid.


Role Of Multicellular Aggregates In Biofilm Formation, Kasper N. Kragh, Jaime B. Hutchison, Gavin Melaugh, Chris Rodesney, Aled E. L. Roberts, Yasuhiko Irie, Peter Ø. Jensen, Stephen P. Diggle, Rosalind J. Allen, Vernita Gordon, Thomas Bjarnsholt Mar 2016

Role Of Multicellular Aggregates In Biofilm Formation, Kasper N. Kragh, Jaime B. Hutchison, Gavin Melaugh, Chris Rodesney, Aled E. L. Roberts, Yasuhiko Irie, Peter Ø. Jensen, Stephen P. Diggle, Rosalind J. Allen, Vernita Gordon, Thomas Bjarnsholt

Biology Faculty Publications

In traditional models of in vitro biofilm development, individual bacterial cells seed a surface, multiply, and mature into multicellular, three-dimensional structures. Much research has been devoted to elucidating the mechanisms governing the initial attachment of single cells to surfaces. However, in natural environments and during infection, bacterial cells tend to clump as multicellular aggregates, and biofilms can also slough off aggregates as a part of the dispersal process. This makes it likely that biofilms are often seeded by aggregates and single cells, yet how these aggregates impact biofilm initiation and development is not known.

Here we use a combination of …


A Model Of The Effects Of Deforestation On Local Climate In The North Cascades, Monica R. H. Jasper Mar 2016

A Model Of The Effects Of Deforestation On Local Climate In The North Cascades, Monica R. H. Jasper

Geography and the Environment: Graduate Student Capstones

Changes in areal extent of land cover types may lead to alterations in the surface energy budget that contribute to anthropogenic climate forcing. This study examines the effects of deforestation in the Cascade Range on local temperature. Temperature sensors were installed in 14 forest stands, taking measurements for one year. Estimated tree age, circumference, and species were recorded to calculate stand density index. Satellite imagery was used to calculate shade fraction from spectral mixture analysis, which is a proxy for canopy structure and density. These data were used to construct seasonal cycles of temperature to model variation with stand density …


March 1, 2016, The Dakota Student Mar 2016

March 1, 2016, The Dakota Student

The Dakota Student

No abstract provided.


Big Data Transforms Discovery-Utilization Therapeutics Continuum., Scott A. Waldman, Andre Terzic Mar 2016

Big Data Transforms Discovery-Utilization Therapeutics Continuum., Scott A. Waldman, Andre Terzic

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Enabling omic technologies adopt a holistic view to produce unprecedented insights into the molecular underpinnings of health and disease, in part, by generating massive high-dimensional biological data. Leveraging these systems-level insights as an engine driving the healthcare evolution is maximized through integration with medical, demographic, and environmental datasets from individuals to populations. Big data analytics has accordingly emerged to add value to the technical aspects of storage, transfer, and analysis required for merging vast arrays of omic-, clinical-, and eco-datasets. In turn, this new field at the interface of biology, medicine, and information science is systematically transforming modern therapeutics across …


Nutrinews, Volume 15, March 2016, Department Of Nutrition And Dietetics, University Of North Florida Mar 2016

Nutrinews, Volume 15, March 2016, Department Of Nutrition And Dietetics, University Of North Florida

NutriNews

This issue features Faculty Spotlight, In the Neighborhood, Kidz Korner, My Passion a personal story


Myonuclear Transcription Is Responsive To Mechanical Load And Dna Content But Uncoupled From Cell Size During Hypertrophy, Tyler J. Kirby, Rooshil M. Patel, Timothy S. Mcclintock, Esther E. Dupont-Versteegden, Charlotte A. Peterson, John J. Mccarthy Mar 2016

Myonuclear Transcription Is Responsive To Mechanical Load And Dna Content But Uncoupled From Cell Size During Hypertrophy, Tyler J. Kirby, Rooshil M. Patel, Timothy S. Mcclintock, Esther E. Dupont-Versteegden, Charlotte A. Peterson, John J. Mccarthy

Physiology Faculty Publications

Myofibers increase size and DNA content in response to a hypertrophic stimulus, thus providing a physiological model with which to study how these factors affect global transcription. Using 5-ethynyl uridine (EU) to metabolically label nascent RNA, we measured a sevenfold increase in myofiber transcription during early hypertrophy before a change in cell size and DNA content. The typical increase in myofiber DNA content observed at the later stage of hypertrophy was associated with a significant decrease in the percentage of EU-positive myonuclei; however, when DNA content was held constant by preventing myonuclear accretion via satellite cell depletion, both the number …


Ectomycorrhizal Fungi Decompose Soil Organic Matter Using Oxidative Mechanisms Adapted From Saprotrophic Ancestors, Firoz Shah, César Nicolás, Johan Bentzer, Magnus Ellström, Mark Smits, Francois Rineau, Björn Canbäck, Dimitrios Floudas, Robert Carleer, Gerald Lackner, Jana Braesel, Dirk Hoffmeister, Bernard Henrissat, Dag Ahrén, Tomas Johansson, David S. Hibbett, Francis Martin, Per Persson, Anders Tunlid Mar 2016

Ectomycorrhizal Fungi Decompose Soil Organic Matter Using Oxidative Mechanisms Adapted From Saprotrophic Ancestors, Firoz Shah, César Nicolás, Johan Bentzer, Magnus Ellström, Mark Smits, Francois Rineau, Björn Canbäck, Dimitrios Floudas, Robert Carleer, Gerald Lackner, Jana Braesel, Dirk Hoffmeister, Bernard Henrissat, Dag Ahrén, Tomas Johansson, David S. Hibbett, Francis Martin, Per Persson, Anders Tunlid

Biology

Ectomycorrhizal fungi are thought to have a key role in mobilizing organic nitrogen that is trapped in soil organic matter (SOM). However, the extent to which ectomycorrhizal fungi decompose SOM and the mechanism by which they do so remain unclear, considering that they have lost many genes encoding lignocellulose-degrading enzymes that are present in their saprotrophic ancestors. Spectroscopic analyses and transcriptome profiling were used to examine the mechanisms by which five species of ectomycorrhizal fungi, representing at least four origins of symbiosis, decompose SOM extracted from forest soils. In the presence of glucose and when acquiring nitrogen, all species converted …


Adiponectin At Physiologically Relevant Concentrations Enhances The Vasorelaxative Effect Of Acetylcholine Via Cav-1/Adipor-1 Signaling., Yunhui Du, Rui Li, Wayne Bond Lau, Jianli Zhao, Bernard Lopez, Theodore A Christopher, Xin-Liang Ma, Yajing Wang Mar 2016

Adiponectin At Physiologically Relevant Concentrations Enhances The Vasorelaxative Effect Of Acetylcholine Via Cav-1/Adipor-1 Signaling., Yunhui Du, Rui Li, Wayne Bond Lau, Jianli Zhao, Bernard Lopez, Theodore A Christopher, Xin-Liang Ma, Yajing Wang

Department of Emergency Medicine Faculty Papers

Clinical studies have identified hypoadiponectinemia as an independent hypertension risk factor. It is known that adiponectin (APN) can directly cause vasodilation, but the doses required exceed physiologic levels several fold. In the current study, we determine the effect of physiologically relevant APN concentrations upon vascular tone, and investigate the mechanism(s) responsible. Physiologic APN concentrations alone induced no significant vasorelaxation. Interestingly, pretreatment of wild type mouse aortae with physiologic APN levels significantly enhanced acetylcholine (ACh)-induced vasorelaxation (P