Digital Commons Network^™

Biochemical Composition Of Caribbean Gorgonian Corals And Their Symbiosis Under Ambeint And Stressful Conditions, Kartick Prakash Shirur

Electronic Theses and Dissertations

Gorgonian corals are the dominant benthic fauna on Caribbean reefs. Unlike scleractinian corals, gorgonian abundance on these reefs has remained stable or has increased. Therefore, to predict how climate change will affect the reef community, it is essential to understand gorgonian physiology under ambient and stressful situations. Under ambient conditions, eight gorgonian species hosted different clade B Symbiodinium, and in two gorgonian species in which the bacterial microbiomes were investigated, two distinct communities were found. In the eight gorgonian species, skeletal content varied from 75-96%, with those having more tissue also having more Symbiodinium density within their branches. The composition …

Fish And Pain: The Politics Of Doubt, Dinesh Joseph Wadiwel

Animal Sentience

The commentaries on Key’s (2016) target article make it clear that there is a great deal of doubt about Key’s thesis that fish do not feel pain. The political question therefore is about how we should respond to doubt. If the thesis of Key and others (that fish do not feel pain) is wrong, then the negative impact for fish in terms of suffering caused by human utilisation would be extreme. In the face of this doubt, the very least we can do is to adopt basic welfare precautions to mitigate the potential impact if fish do suffer, with attention …

The Association Between Physical Activity And Serum Immunoglobulin G (Igg) Antibodies Against Periodontal Bacteria, A. Paige Anderson

Theses and Dissertations

The purpose of this study is to add more research and evidence to the mechanisms surrounding periodontal disease, periodontal microorganisms, and physical activity. The main objective of this study is to evaluate and explore the association between physical activity and serum IgG antibodies, which are grouped into four distinct clusters, formed from species specific 19 periodontal antibody titers. This cross sectional study divided physical activity into three categories: adequately physically active, inadequately physically active, and inactive based on MET scores. Certain models were adjusted for confounders including age, sex, race/ethnicity, income-to-poverty ratio, years of formal education, smoking, alcohol intake, BMI, …

Mass Spectrometry-Based Protein Profiling And Investigations Of Tgf-Ss1-Induced Epithelial-Mesenchymal Transition Signatures In Namru Murine Mammary Gland Epithelial Cells, Matsepo Ramaboli

Theses and Dissertations

Breast cancer is the second-most common cancer and the second-leading cause of cancer-related deaths in women. Despite advances in cancer early detection, prevention and treatment, breast cancer is still a major health challenge due to low survival caused by breast cancer metastasis. This warrants critical attention and intervention. From the proteomic standpoint, a protein-based multiplex system that provides large array of informative signals for cancer identification and prognosis is still limited. In this dissertation work, we developed two mass spectrometry-based strategies involving chemical biology tools for rapid protein fingerprinting of breast cancer cell lines, and for probing the O-linked N-acetylglucosamine …

Enhancing Parent-Child Communication And Promoting Physical Activity And Healthy Eating Through Mobile Technology: A Randomized Trial, Danielle E. Schoffman

Theses and Dissertations

Background

Although rates of pediatric and adult obesity remain high in the U.S., finding scalable and engaging ways to disseminate obesity prevention and treatment for families has been challenging. The purpose of the Motivating Families with Interactive Technology (mFIT) study was to test the feasibility, acceptability, and effectiveness of two remotely-delivered family-based health promotion programs for improvements physical activity (PA), healthy eating, and parent-child communication and relationship quality.

Methods

Parent-child (child age 9-12 years) dyads enrolled in a 12-week mobile intervention to increase physical activity and healthy eating, which included weekly email newsletters and the use of pedometers. Dyads were …

Depression Among Pregnant Latinas In South Carolina, Andrew Fogner

Theses and Dissertations

The aim of the study was to determine the prevalence of depression among pregnant Latinas. To bring to light the importance of prenatal depression prevention, we assessed the effect of the quality of healthcare providers among South Carolina Latinas (n=171). Women answered a validated CES-D and were categorized as depressed (score >16). In multivariate analyses, good perception of quality of healthcare was more likely among women who were not depressed; adjusted odds ratio of 0.75, 95% confidence interval 0.37 – 1.55. The findings show the need for tailoring healthcare to Latinas with prenatal depression prevention. It is imperative to understand …

Regulation Of Chronic And Acute Inflammatory Disease By Microrna And Microbiota, Pegah Mehrpouya-Bahrami

Theses and Dissertations

Inflammation is implicated in cancer development, degenerative diseases, allergies as well as artherosecelorsis. Dysregulated immune responses lead to chronic inflammation and tissue damage. Finding the ways to terminate inflammatory responses when no longer needed, demands further investigation. Herein, we investigated the modulation of acute and chronic inflammatory disease models by inducing antiinflammatory state. Acute inflammatory model was induced with SEB, an enterotoxin produced by a ubiquitous Gram-positive coccus, Staphylococcus aureus (S. aureus), which exerts profound toxic effects on the immune system, which leads to the cytokine storm and adverse immune response. SEB is the main cause of nosocomial infections, acute …

Exploratory Analysis Of Ptsd Severity And Objective Measures Of Physical Activity Among Combat Veterans, Danny O. Sauceda

Theses and Dissertations

Strong levels of motivation, relatedness and self-determination support the likeliness of participating in habitual exercise. Compared to nationwide estimates, research has demonstrated fitness and performance is significantly lower among those suffering from PTSD. Meeting established recommended daily levels of physical activity (PA) for individuals with PTSD is critical for their physical and mental health status over a lifetime and factors supporting or hindering adherence to habitual exercise are lacking. Furthermore, regular PA among combat Veterans with Posttraumatic Stress Disorder (PTSD) is a viable and substantial treatment option to improve physical health status and cognitive well-being. The purpose of this exploratory …

Mislabeling Of Commercial Atlantic Cod (Gadus Morhua) Products In Spain, Joshua Helgoe

Theses and Dissertations

The mislabeling of commercial fish products is a pervasive, worldwide problem. Most consumers of seafood are unaware this issue directly affects them and can even have negative impacts on their health. Mislabeling occurs when a product’s label is inconsistent with its content. Although mislabeling can be unintentional, deliberate mislabeling is a more common trend to increase profits and/or bypass fishing regulations - a form of economic fraud. Unfortunately, oversight, enforcement, and research are vastly insufficient in relation to the global scale of the problem. In order to add to the small knowledge base on European mislabeling rates, determine if overfished …

Exploring Children’S Physical Activity Levels Through Structure And Measurement, Jessica L. Chandler

Theses and Dissertations

The purpose of this dissertation was twofold: 1) to establish best practices for wrist-based accelerometry for 5-11 year old children and 2) to explore the contribution of activity structure to children’s physical activity (PA) levels.

The purpose of study 1 aimed to determine differences in counts/5second epoch produced by the dominant and non-dominant wrist during seated, sedentary activities in 5-11 year old children and ultimately create a cutpoint threshold to distinguish seated sedentary behavior from light physical activity. 167 children, ages 5-11 years, performed up to 8 sedentary activities for 5 minutes while wearing ActiGraph GT3X+ accelerometers on both wrists. …

Mysleep101©: An Educational Mobile Medical Application For Sleep Health In Primary Care, Sonya Cook

Theses and Dissertations

Insufficient sleep has emerged over the past few decades as a public health concern. As little as 1 to 2 hours of sleep loss can produce extreme fatigue and physiological drives similar to thirst and/or hunger which increases the risk of motor vehicle accidents, work related mistakes and injuries. Sleep restriction whether voluntary or involuntary has produced a culture of chronic sleep deprivation that can be seen throughout the population. Chronic lack of quality sleep has been shown to adversely affect cardiovascular health, cognitive function, memory, immune responses and hormonal regulation among other homeostatic functions. Sleep disorders represent the cause …

Quality Over Quantity: Positive Interactions During Family Meals In Food-Insecure Households Compensate For The Negative Impacts Of Household Chaos On Child Emotional Well-Being, But Not Diet Quality, Tiara Nicόl Rosemond

Theses and Dissertations

Family meals are important family activities that have many positive nutritional and emotional benefits for children. Positive family meal experiences may provide opportunities for children to strengthen emotional bonds, leading to a sense of security and, fostering improved children’s self-regulation of healthier food intake and emotional well-being. Unfortunately, children in food insecure households experience higher amounts of chaos, lower diet quality, and worry about having enough to eat compared to children in food-secure households, all of which may affect both family meal frequency and interpersonal quality. Yet, the relationships between food insecurity, household chaos, and family meal frequency and interpersonal …

The Influence Of Prenatal And Early Life Factors On Bmi Z Scores And The Risk Of Being Obese In Early Childhood, Junxiu Liu

Theses and Dissertations

Childhood obesity is a serious public health challenge. The underlying causes behind the rising levels of childhood obesity might be driven by prenatal and early life factors. Recently, several studies have examined the association between gestational weight gain (GWG) and the risk of obesity in the pediatric population. Findings on the association of both inadequate and excessive GWG with offspring obesity are inconsistent and vary by maternal prepregnancy body mass index (BMI) status. Inconsistent findings also exist for the association of GWG and BMIZ as a continuous outcome. Nevertheless, existing studies mainly focus on the BMIZ upper centiles using logistic …

Exploring The Relationship Between Church Level Predictors Of Status And Obesity Risk In African American Women Of Faith, Kinjal Pandya

Theses and Dissertations

Although obesity is a nationwide epidemic, there are large racial, gender, socioeconomic, and geographical disparities in the rates of this condition. Specifically, African American women are more likely to be classified as obese as compared to all other gender and racial groups. Scholars have targeted African American churches to implement dietary and physical activity interventions in an attempt to combat the racial disparity in obesity rates. One of the main correlates studied in regards to obesity has been individual level markers of status such as socioeconomic status and subjective social status. Even though we focus on churches as a place …

Electrochemical Detection Of Antioxidants, Garrett Thompson

Honors Theses and Capstones

No abstract provided.

Stimuli Responsive Nanoparticle For Cancer Targeted Therapy, Huacheng He

Theses and Dissertations

Nanoparticle is the particle with a size in the range from several nanometers to hundreds of nanometers. It has been extensively used for cancer diagnosis and therapy. However, it is still a great challenge to fabricate nanoparticles with spatiotemporally controllable delivery of anticancer drugs to tumors and with high therapeutic efficacy. This thesis mainly focuses on the development of stimuli responsive nanoparticles for cancer targeted therapy. These nanoparticles either response to internal stimuli such as pH and redox potential or external stimuli like temperature and light could effectively target tumors and control the release of anticancer drugs there to improve …

Promoting Progress To Assist Youth With Disordered Eating In School Mental Health, Bryn Elizabeth Schiele

Theses and Dissertations

Disordered eating has become a significant issue among children and adolescents; nearly 14% of all youth displaying disordered eating patterns. Despite the prevalence of these disorders amongst school-age students, there is a deficit of empirical literature on the integration of eating disorder support services in schools, as well as a lack of knowledge and training of school mental health (SMH) professionals regarding the appropriate interventions for this population. While eating disorders have previously been considered as outside of the school mental health domain of practice (e.g., Judge, 2001), this view has changed and there exists a significant need to provide …

Breastfeeding Among Working Mothers In Saudi Arabia, Maryam Suliman Alhabas

Theses and Dissertations

Objective: To examine the relationship of not having breastfeeding support policy in workplace such as employees pumping breast milk or breastfeeding their infant while at work policy to early initiation of formula and cessation of breastfeeding. Design: Crosssectional study. Setting and Subjects: A total of 273 workingwomen, working in 12 different organizations in Riyadh, KSA. Method: An electronic questionnaire survey was administered to 340 workingwomen in 12 different organizations in Riyadh. Questions were about participants’ demographics and employment characteristics, breastfeeding support services in their workplace, knowledge about breastfeeding benefits, breastfeeding duration after return to work, and formula initiation. Results: Having …

Synthesis And Photonic Sintering Of Bioresorbable Zinc Nanoparticle Ink For Transient Electronics Manufacturing, Bikram K. Mahajan

Masters Theses

"Zinc is an essential 'trace element' that supports immune systems, and is required for DNA synthesis, cell division, and protein synthesis. Zinc nanoparticles (Zn NP) has antibacterial properties and potential to be used in biodegradable printed electronics devices. The research presented here is about the synthesis of Zn NP and their potential use in transient electronics devices. In Paper 1, a technique of room temperature synthesis of Zn NP is reported using ball milling. Controlled amount of PVP was mixed in the solvent to stabilize the Zn particles and minimize cold welding during milling. The size of the produced Zn …

Contribution Of New Thiol Antioxidant In The Treatment Of Acetaminophen Toxicity, Ahdab Naeem Khayyat

Doctoral Dissertations

"Acetaminophen (N-acetyl-p-aminophenol, APAP) is one of the most widely used over-the-counter antipyretic analgesic medications. It is safe at therapeutic doses, but an overdose can result in severe hepato-nephrotoxicity, a leading cause of drug-induced acute liver failure in the U.S. Although a few different mechanisms have been proposed for APAP-induced toxicity, a significant amount of evidence has pointed to the potential involvement of oxidative stress in acetaminophen toxicity. Depletion of glutathione (GSH) is one of the initiating steps in APAP-induced toxicity; therefore, one strategy for restricting organ damage is to restore GSH levels by using GSH prodrugs like N-acetylcysteine (NAC). Although …

Female Natural Bodybuilding Competition Preparation: A 6-Week Case Study, Samantha G. Gwazdauskas

College of Graduate Studies: Theses & Dissertations

Bodybuilding is unlike any other sport. Competitors are judged on appearance rather than performance, where muscle size and definition are keys to achieving success. This case study tracked four, drug-free, female bodybuilders for 6-weeks leading up to their competitions. The purpose of this project was to examine the physiological and psychological experiences of female bodybuilders as they prepare for competition. Each competitor reported for testing at three occasions to evaluate cardiovascular measures, body composition, resting metabolic rate, performance measures of strength, power, muscular endurance, and maximal oxygen consumption, mood state, social physique anxiety, and overall experience. Each subject in this …

An Exploration Of The Relationships Between Chronic Pain, Inflammation, And Herbal Medicine, Termeh Feinberg

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Inflammation is often a component of chronic pain, yet its potential role in fibromyalgia syndrome (FMS) remains inconclusive. FMS is a complex chronic pain condition affecting ~2% of the population; management is challenging and treatment options remain limited. Many herbs contain anti-inflammatory properties, and herbs indicated for analgesia and rheumatic conditions have traditionally been used in Appalachia. Despite the popularity of herbs in the US, determinants and patterns of herbal use with regard to pain management have not been well studied, particularly in Appalachia, where prevalence of chronic pain and related comorbid conditions is high and access to medical …

Group Empathy In Response To Non-Verbal Racial/Ethnic Cues: A National Experiment On Immigration Policy Attitudes, Cigdem Sirin, Nicholas Valentino, José Villalobos

Departmental Papers (PS)

No abstract provided.

Anglican-Roman Catholic Ecumenical Dialogue: A Case For A Rahnerian Logic Of Symbol, Eric S. Dart

Electronic Theses and Dissertations

This dissertation examines the ecumenical relationship between the Roman Catholic Church and the Anglican Communion and the necessity for a symbolic cognitive and narrative conversion in both communions. Drawing upon Karl Rahner's theology of symbol, this dissertation argues that such a cognitive and narrative conversion is determined by the interpretation and appropriation of God's mystery as the origin and goal of Christian activity and belief. As such, there is a demand for a second naïveté in both communions, whereby, the methods employed by ecumenical dialogue extend beyond the logic of criticism and seek to embrace a postcritical logic of symbol.

Effect Of The Ethylene Inhibitors Silver Nitrate, Silver Sulfate, And Cobalt Chloride On Micropropagation And Biochemical Parameters In The Cherryrootstocks Cab-6p And Gisela 6, Virginia Sarropoulou, Kortessa Dimassi-Theriou, Ioannis Therios

Turkish Journal of Biology

In the present study, the effects of three ethylene inhibitors, silver nitrate (AgNO3), silver sulfate (Ag2SO4), and cobalt chloride (CoCl2), on the morphogenic and biochemical responses in CAB-6P and Gisela 6 cherry rootstocks were investigated. In both rootstocks, AgNO3 and Ag2SO4 promoted shoot regeneration while CoCl2 had such an effect only in Gisela 6. The rooting percentage of CAB-6P and Gisela 6 explants was diminished with AgNO3, Ag2SO4, and CoCl2. AgNO3 increased root number (40 μM) and root length (50 μM) in the CAB-6P rootstock while it had an inhibitory effect in Gisela 6. Ag2SO4 and CoCl2 enhanced root length …

The Architecture Of A Basic Income, Miranda Perry Fleischer, Daniel Hemel

Public Law and Legal Theory Working Papers

The notion of a universal basic income (UBI) has captivated academics, entrepreneurs, policymakers, and ordinary citizens in recent months. Pilot studies of a UBI are underway or in the works on three continents. And prominent voices from across the ideological spectrum have expressed support for a UBI or one of its variants, including libertarian Charles Murray, Facebook cofounder Chris Hughes, labor leader Andy Stern, and—most recently—former President Barack Obama. Although even the most optimistic advocates for a UBI will acknowledge that nationwide implementation lies years away, the design of a basic income will require sustained scholarly attention. This Article seeks …

Antimicrobial Stewardship In Long-Term Care Facilities: A Call To Action, Haley J. Morrill, R. Caffrey, Robin L. P. Jump, David Dosa, Kerry L. Laplante

Pharmacy Practice and Clinical Research Faculty Publications

Antimicrobial resistance is a global public health crisis and a national security threat to the United States, as stated in an executive order signed by the president in September 2014. This crisis is a result of indiscriminant antimicrobial use, which promotes selection for resistant organisms, increases the risk of adverse drug events, and renders patients vulnerable to drug-resistant infections. Antimicrobial stewardship is a key measure to combat antimicrobial resistance and specifically seeks to do this by improving antimicrobial use. Antimicrobial stewardship compliments infection control practices and it is important to note that these 2 disciplines are distinct and cannot be …

The Effect Of Molecular Rapid Diagnostic Testing On Clinical Outcomes In Bloodstream Infections: A Systematic Review & Meta-Analysis, Tristan T. Timbrook, B. Morton, Kevin W. Mcconeghy, Aisling R. Caffrey, Eleftherios Mylonakis, Kerry L. Laplante

Pharmacy Practice and Clinical Research Faculty Publications

Background. Previous reports on molecular rapid diagnostic testing (mRDT) do not consistently demonstrate improved clinical outcomes in bloodstream infections (BSIs). This meta-analysis seeks to evaluate the impact of mRDT in improving clinical outcomes in BSIs.

Methods. We searched PubMed, CINAHL, Web of science, and EMBASE through May 2016 for BSI studies comparing clinical outcomes by mRDT and conventional microbiology methods.

Results. Thirty-one studies were included with 5,920 patients. Risk of morality was significantly lower with mRDT as compared to conventional microbiology methods (OR 0.66, 95% CI 0.54-0.80) yielding a NNT of 20. The risk of mortality was …

Histological Evidence Of The Effect Of Oil Palm Phenolics In Atherogenic Diet Induced Rat Model Of Alzheimer’S Disease, Kenechukwu Monplaisir Monplaisir

Wayne State University Theses

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disease with the clinical presentation of memory loss and cognitive impairment. Alzheimer's disease pathology is the accumulation of beta amyloid plaques and neurofibrillary tangles.

METHOD: In this study atherogenic diet was used to induce AD in aged Brown Norway rats. The rats were assigned to the following four groups fed isocaloric diets; control group (C ),high cholesterol diet (H), high cholesterol + oil palm phenolics group (HP), high cholesterol + curcumin group (HC). The impact of oil palm phenolics (OPP) on neuronal health and its effect on amyloid deposition was evaluated using histology …

In Vitro Gastrointestinal Digestion Model To Monitor The Antioxidant Properties And Bioaccessbility Of Phenolic Extracts From Elderberry (Sambucus Nigra L.), Ninghui Zhou

Wayne State University Theses

This study performed an in vitro gastrointestinal digestion model to monitor the antioxidant properties of phenolic extracts derived from the elderberry (Sambucus nigra L.). The stability and antioxidant qualities of phenolic compounds from elderberry were assessed by an in vitro gastrointestinal digestion model involving pepsin digestion (to simulate gastric digestion) and pancreatin digestion (to simulate small i22ntestine conditions). Digested and undigested elderberry were subject to antioxidant assays including total phenolic content (TPC) assay, DPPH radical scavenging assay, and oxygen radical absorbance capacity (ORAC) assay. Our result showed that digestion process significantly reduced DPPH radical scavenging activity but had no significant …