Digital Commons Network^™

Drug-Induced Nutrient Depletion, Rodney Richmond

Faculty Research ​and Publications

No abstract provided.

A Review Of Needs And Challenges Facing Unaccompanied Alien Children (Uac) Released Into U.S. Communities, Dorothy L. Mcleod

Center for the Human Rights of Children

Immigrant children (<18 years) who enter the United States alone and without legal status are defined as unaccompanied alien children (UAC ), according to United States law. Between 2013 and 2015, the number of unaccompanied immigrant children arriving at the United States-Mexico border increased dramatically, reaching a peak of over 55,000 in FY 2014. While a number of research and policy documents detail the movement of youth through the immigration system, little is known about this population after their release to sponsors in the U.S. The current research brief synthesizes the existing research using a multi-disciplinary approach. We have chosen to prioritize peer-reviewed research, but have also included information from governmental and NGO reports. Each of the following sections summarizes the research on a different aspect of youth’s postr-elease adjustment to life in the United States. We conclude the report with a list of unanswered research questions.

Design And Evaluation Of Hmp Kinase Analogs As Thiamine Pathway Inhibitors, Diego A. Lopez

Chemistry & Biochemistry Dissertations - Archive

Current bacterial chemotherapy faces an overwhelming reduction in efficacy due to an increase in bacterial resistance; resulting in a higher clinical demand for novel therapeutics and the investigation for their respective targets. Vitamin pathways exogenous to the human body represent an attractive target for drug development since the enzymatic machinery is solely and ubiquitously to many infectious agents. HMP kinase [E.C 2.7.1.49] is a key enzyme in the thiamine metabolism. It catalyzes two subsequent phosphorylations of 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP), making it indispensable for microbial survival. Our efforts aimed for a substrate-based approach, where over 50 HMP analogs were synthesized and assayed …

Stakeholders’ Perceptions And Practice Of Culturally Responsive Pedagogy In A Private School, Elizabeth Maria Franklin

Dissertations

Many culturally responsive theorists support culturally responsive pedagogy for closing the achievement gap in the rapidly changing demographics of America’s education system. The purpose of this case study was to examine stakeholders’ perceptions and practice of culturally responsive pedagogy in St. Andrew Academy (pseudonym), a Catholic NativityMiguel school located in a Midwest metropolitan area. The goals were: (a) to examine middle school teachers’ and the principal’s perceptions of culturally responsive pedagogy and extent of culturally responsive teaching implemented in the school, (b) to examine how parents perceived culturally responsive caring relationships with teachers and the principal, and (c) to examine …

Type 2 Diabetes Mellitus (T2dm) Onset And "Remission"., Srikanth Tangelloju

Electronic Theses and Dissertations

Background: Type 2 diabetes mellitus (T2DM) is a progressive disease condition. As the disease progresses the function of beta (β) cells (cells which regulate insulin) decline, thereby increasing the circulating blood glucose levels. If left unmanaged the disease progresses from onset to development of T2DM related complications and eventually death. When managed, in certain individuals, T2DM onset can be prevented and/or slowed down and in certain T2DM individuals, remission is observed. There are some known modifiable risk factors such as diet and physical activities that are associated with the speed and direction of progression, but much is still unknown. In …

Vinyl Chloride-Diet Interactions In Liver Disease : Potential Roles Of Autophagy And Energy Management., Anna L. Lang

Electronic Theses and Dissertations

Vinyl chloride (VC) is a prevalent environmental toxicant that has been shown to cause liver injury at high, occupational exposures. However, most studies have not addressed interactions of low doses with risk-modifying factors. This study aims to explore low-level VC metabolite exposure interactions with other potential risk-modifying factors and their effect on underlying liver disease. We examined sub-hepatotoxic effects of a VC metabolite (chloroethanol, CE) in two murine models of liver injury using ethanol and lipopolysaccharide (LPS). In both, CE significantly enhanced liver injury when compared to either ethanol or LPS alone. Previous studies have shown an increase in mTOR …

Toll-Like Receptor 4 Mutation Suppresses Hyperhomocysteinemia-Mediated Hypertension., Anastasia Familtseva

Electronic Theses and Dissertations

Background: Hyperhomocysteinemia (HHcy) has been observed to promote hypertension, but the mechanisms are unclear. Toll-like receptor 4 (TLR-4) is a cellular membrane protein that is ubiquitously expressed in all cell types of the vasculature. TLR-4 activation has been shown to promote inflammation that has been associated with pathogenesis of hypertension. In this study, we hypothesize that HHcy induces hypertension by TLR-4 activation that promotes inflammatory cytokine up-regulation (IL-1β, IL-6, TNF-α) and initiation of mitochondrial dysfunction leading to cell death and chronic vascular inflammation. Methods: To test this hypothesis, we used C57BL/6J mice (WT); Cystathionine-β-synthase deficient mice (CBS+/-) with genetic mild …

Rumination, Worry, And Drinking Behaviors In College Students : A Mediation Analysis., Stephanie Winkeljohn Black

Electronic Theses and Dissertations

Mental health and alcohol-related behaviors are constructs of concern on university campuses, as a significant portion of college students experience alcohol-related consequences. There is an established link between mental health variables, including repetitive thoughts associated with depression and anxiety, and drinking behaviors among college students. However, how preventative behaviors – protective behavioral strategies – impact the associations between repetitive thoughts and drinking behaviors and outcomes is less understood. The current longitudinal study analyzed mediational relationships among these variables in college students at a mid-sized 4-year university (N = 107; 78.5% female; average age = 21.06 years, SD = 4.41). Analyses …

The Effects Of Zinc Supplementation From Two Sources On Egg Quality And Bone Health In Laying Hens, Kelli Marie Martin

Department of Animal Science: Dissertations, Theses, and Student Research

The objective of this study was to compare zinc sources and levels of supplementation on laying hen performance. Bovan White Leghorn hens were fed one of six dietary treatments in a 2x3 factorial arrangement consisting of two zinc sources (Availa®Zn or zinc sulfate) and three levels (40, 80, or 120 ppm). Treatments were randomly assigned to 48 cages with five hens/cage. Blocks provided eight replicates/treatment. Hens were housed in a tiered manure belt housing system providing 97.2 cm²/hen. Hens were given 110 g/hen/day of feed ad libitum. Feed intake, egg production, egg weights, egg components, eggshell strength, body …

Evaluation Of The Metabolic Response, Blood Chemistry Profile, And Cardiac Morphology Of Beef Heifers Supplemented With Zilpaterol Hydrochloride Followed By An Endocrine Induced Stress Challenge, Joe O. Buntyn

Department of Animal Science: Dissertations, Theses, and Student Research

The objective of this study was to determine the metabolic, stress, hematology, organ weights, histology and cardiac anatomical features of beef heifers supplemented with zilpaterol hydrochloride (ZH) when exposed to a corticotropin-releasing hormone (CRH) and arginine vasopressin (VP) challenge. Crossbred heifers (n = 20; 556 ± 7 kg BW) were randomized into two treatment groups: 1) Control (CON): no ZH, and 2) Zilpaterol (ZIL): supplemented with ZH at 8.33 mg / kg (DM basis). The ZIL group was supplemented ZH for 20 d, with a 3-d withdrawal period. On d 24, heifers received an intravenous bolus of CRH (0.3 µg …

Effects Of Salt And Nitrite Concentration On The Shelf Life Of Deli-Style Ham, Regan Elise Stanley

Department of Animal Science: Dissertations, Theses, and Student Research

Deli-style hams were manufactured to measure the effects of salt and nitrite concentration on shelf life and physicochemical characteristics. Three replications of deli-style ham treatments were manufactured in a 3 x 4 factorial arrangement of salt concentration (0.7%, 1.4%, or 2.1%, meat block basis) and nitrite concentration and source (0 ppm, 100 ppm or 200 ppm sodium nitrite, SN, or 100 ppm sodium nitrite equivalent from pre-converted celery juice powder, CP; Veg Stable 506, Florida Food Products). Salt concentration, water activity, cook yield, and texture profile analysis (TPA) were measured on w 0. Color, pH, residual nitrite, and aerobic and …

Development Of Terminal And Maternal Economic Selection Indices In Beefmaster Cattle, Kathleen Pearl Ochsner

Department of Animal Science: Dissertations, Theses, and Student Research

In the design of economic selection indices, the relative importance of traits in the breeding objective is reflected by their relative economic weighting. The objective of this study was to develop two economic selection indices for Beefmaster cattle: one for a terminal production system and one for a maternal production system. The terminal index was developed assuming bulls are mated to mature cows with all resulting progeny harvested. The maternal index was developed assuming bulls are mated to a combination of heifers and mature cows, with resulting progeny retained as replacements or sold at weaning.

National average prices from 2010 …

Impact Of Finishing Diets With De-Oiled Distillers Grains Or Antioxidant Containing Supplement On Beef Shelf Life, Katherine I. Domenech-Pérez

Department of Animal Science: Dissertations, Theses, and Student Research

In its entirety this dissertation intended to address the impact of feeding several forms of de-oiled corn distillers grains plus solubles and the effect of supplementing OmniGen-AF as a potential antioxidant source for extending beef shelf life. In study one we learned that despite the de-oiling process, greater inclusion levels (65%, DM basis) of de-oiled wet distillers grains plus solubles (WDGS) causes an increase in polyunsaturated fatty acids (PUFA) similar to the levels obtained with full-fat WDGS. Lower inclusion levels (35 and 50%, DM basis) of de-oiled WDGS have intermediate PUFA content in comparison to 65% de-oiled WDGS, full-fat WDGS …

Forage News [2016-08], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Eden Shale Farm to Host KFGC Field Day Sept. 13th
• Forage News Quote of the Month: "Forages, particularly the Grasses, are the most important plants on the face of the earth"
• Sugarcane Aphid Found in Kentucky
• UK Breeder Develops New Tall Fescue Variety
• Featured Publication: Stockpiling for Fall and Winter Pasture (AGR-162)
• Planting Brassicas and Cereals for Fall Forage
• Choose Varieties Wisely

General Catalog 2016-2017, Utah State University

University Catalogs

This catalog contains information on the Academic Departments and Programs as well as Course Descriptions for the above school year at Utah State University. To avoid large file downloads, the Academic Departments and Programs information is located in this file. The Course Description information is located in the secondary file.

Metaplus: An R Package For The Analysis Of Robust Meta-Analysis And Meta-Regression, Ken J. Beath

The R Journal

The metaplus package is described with examples of its use for fitting meta-analysis and meta-regression. For either meta-analysis or meta-regression it is possible to fit one of three models: standard normal random effect, t-distribution random effect or mixture of normal random effects. The latter two models allow for robustness by allowing for a random effect distribution with heavier tails than the normal distribution, and for both robust models the presence of outliers may be tested using the parametric bootstrap. For the mixture of normal random effects model the outlier studies may be identified through their posterior probability of membership in …

The R Journal (August 2016) 8(1): Complete Issue, The R Foundation

The R Journal

Editorial, Michael Lawrence

Contributed Research Articles

metaplus: An R Package for the Analysis of Robust Meta-Analysis and Meta-Regression, Ken J. Beath

Gender Prediction Methods Based on First Names with genderizeR, Kamil Wais

Conditional Fractional Gaussian Fields with the Package FieldSim, Alexandre Brouste, Jacques Istas, and Sophie Lambert-Lacroix

rTableICC: An R Package for Random Generation of 22K and RC Contingency Tables, Haydar Demirhan

Maps, Coordinate Reference Systems and Visualising Geographic Data with mapmisc, Patrick E. Brown

Variable Clustering in High-Dimensional Linear Regression: The R Package clere, Loïc Yengo, Julien Jacques, Christophe Biernacki, and Mickael Canouil

Stylometry with R: A Package for …

Understanding Nutritional Habits Of Refugees From Burma, Brian Blake Davis

Social Work Theses - Archive

This research study examines the nutritional practices of a 21-year-old Karen, female, refugee. All aspects of nutritional practices are examined, including favorite foods, differences between foods due to geographical region, where food is acquired, and familial practices. Grounded theory was used to examine a single, transcribed, interview, for emerging themes. Two researchers coded the data for themes, and then data was compared for accuracy. Results help to highlight an in-depth analysis of a Karen refugee, and can be used to compare and contrast the nutritional practices of other refugees from Burma. Emerging themes include eating habits, food access, and acquisition, …

The Role Of Hotair In Skeletal Muscle Myogenesis, Fritzlaine Roche

Chemistry & Biochemistry Theses - Archive

Skeletal muscle function is a vital requirement for an enriched healthy life. For years the molecular processes governing myogenesis and the development of skeletal muscle were primarily associated with proteins. In recent years, however, non-coding RNAs including microRNAs (miRNAs) and long non coding RNAs (lncRNAs) have emerged as integral components of gene regulation that take part in cellular differentiation, development and disease. HOTAIR (HOX antisense intergenic RNA) is a long non-coding RNA (lncRNA) that is transcribed from the antisense strand of the homeobox C (HOXC) gene locus present on chromosome 12. HOTAIR has been shown to have a regulatory role …

The Influence Of Race, Economics, Neighborhood, And School Category On The Severity Of Adhd Symptoms, Angel Linh Nguyen

MA Community Psychology Theses

An ordinal regression method was used to model the relationship between the ordinal outcome variable, an ADHD index created for the purpose of this research, and the predictor variables of Race, Economics, Neighborhood Rating, and School Category/Type. A secondary data analysis of the Panel Study of Income Dynamics (PSID) and Child Development Supplement (CDS) was used in this study. The final sample consisted of 1,169 elementary, middle, and high school children ages 9-18. Six analyses were conducted to determine the best fit model for the data: a combined model with all the predictor variables, one for each individual predictor variable, …

The Role Of Developmental Plasticity In Response To Salinity On The Evolution Of Alternative Reproductive Tactics In The Sailfin Molly, Poecilia Latipinna (Poeciliidae: Poecilia: Mollienesia), Kelly Elise Hogan

All Theses

Variability in life history and morphology across conspecific populations is a widespread phenomenon and may be attributed to life history trade-offs in response to environmental variation. Such trade-offs between growth, maintenance, and reproduction often occur via developmental plasticity, which allows organisms to shift their developmental trajectories to maximize fitness in a given environment. Sailfin mollies (Poecilia latipinna) exhibit interpopulation variation in life history and morphological traits, and inhabit springs, tidal creeks, and estuaries that range from freshwater to seawater. Male size at maturity is smaller on average in freshwater springs than in brackish water marshes where these fish are most …

Anti-Incarcerative Remedies For Illegal Conditions Of Confinement, Margo Schlanger

University of Miami Race & Social Justice Law Review

No abstract provided.

Refugee Resettlement And Peacebuilding: Exploring The Roles Of Human And Social Capital Of Caseworkers In Fulfilling Grassroots Refugee Needs, Pranaya S. Rana

Doctor of International Conflict Management Dissertations

Refugee resettlement provides reintegration opportunities for refugees and paves a path for sustainable peacebuilding through refugee empowerment. Despite these benefits, the often inadequate outcomes of resettlement present challenges for both the refugees and their service providers. Refugee caseworkers must meet their clients’ needs and provide certain services to their clients within a limited time period. This makes helping refugees gain economic self-sufficiency a daunting task. Often, failure to achieve resettlement goals is attributed to the refugees for not possessing the desired skills or networks (human and social capital). This research explores how caseworkers’ characteristics such as education, experience, and specialized …

Diabetes, Insulin Secretion, And Beta Cell Function, Jeffery Tessem

BYU Research Development Office Research Networking Conference

The intricate processes of nutrient metabolism and their biochemical pathways are fundamental to understanding human physiology and health. This research focuses on exploring the biochemical mechanisms underlying nutrient metabolism and how deviations in these processes can lead to metabolic disorders and associated human diseases.

Guideline For Stakeholder Engagement On Aquatic Resource Management-Related Processes, Department Of Fisheries

Fisheries Occasional Publications

No abstract provided.

A Fungal Endophyte Helps Plants To Tolerate Root Herbivory Through Changes In Gibberellin And Jasmonate Signaling, Marco Cosme, Jing Lu, Matthias Erb, Michael Joseph Stout, Philipp Franken, Susanne Wurst

Faculty Publications

© 2016 The Authors. New Phytologist © 2016 New Phytologist Trust. Plant–microbe mutualisms can improve plant defense, but the impact of root endophytes on below-ground herbivore interactions remains unknown. We investigated the effects of the root endophyte Piriformospora indica on interactions between rice (Oryza sativa) plants and its root herbivore rice water weevil (RWW; Lissorhoptrus oryzophilus), and how plant jasmonic acid (JA) and GA regulate this tripartite interaction. Glasshouse experiments with wild-type rice and coi1-18 and Eui1-OX mutants combined with nutrient, jasmonate and gene expression analyses were used to test: whether RWW adult herbivory above ground influences subsequent damage caused …

Maternal Obesity Epigenetically Alters Visceral Fat Progenitor Cell Properties In Male Offspring Mice, Xingwei Liang, Qiyuan Yang, Xing Fu, Carl J. Rogers, Bo Wang, Hong Pan, Mei Jun Zhu, Peter W. Nathanielsz, Min Du

Faculty Publications

© 2016 The Authors. The Journal of Physiology © 2016 The Physiological Society Key points: Maternal obesity reduces adipogenic progenitor density in offspring adipose tissue. The ability of adipose tissue expansion in the offspring of obese mothers is limited and is associated with metabolic dysfunction of adipose tissue when challenged with a high-fat diet. Maternal obesity induces DNA demethylation in the promoter of zinc finger protein 423, which renders progenitor cells with a high adipogenic capacity. Maternal obesity demonstrates long-term effects on the adipogenic capacity of progenitor cells in offspring adipose tissue, demonstrating a developmental programming effect. Abstract: Maternal obesity …

Association Between 25-Hydroxyvitamin D And Intact Parathyroid Hormone Levels Across Latitude Among Adults With African Ancestry, Holly Kramer, Pauline Camacho, John Aloia, Amy Luke, Pascal Bovet, Jacob Plange Rhule, Terrence Forrester, Vickie Lambert, Regina Harders, Lara Dugas, Richard Cooper, Ramon Durazo-Arvizu

Faculty Publications

Objective: To compare levels of 25-hydroxyvitamin D (25OHD) associated with a plateauing of intact parathyroid (iPTH) across latitudes among adults with African ancestry. Methods: This study included approximately 500 adults of African ancestry ages 25 to 45 years living in 4 sites: Chicago, Illinois (41°N), Jamaica (17°N), Ghana (6°N), and South Africa (34°S). Multivariate linear regression models, a nonlinear logistic growth curve model, and piecewise linear models with a single knot were fitted to estimate the 25OHD level associated with a plateauing of iPTH with adjustment for covariates. Goodness of fit was compared using computer intensive permutation tests. Results: Mean …

Effects Of Ultra-Violet B On The Behavior Of Red-Eared Sliders (Trachemys Scripta Elegans), Edgar Alarcon

Theses and Dissertations

This study aimed to test the predictions that (1) turtles raised under mercury vapor artificial lamps will display the greatest amount of time spent in ultra-violet zones, and (2) turtles are able to differentiate between UVB and non-UVB light sources. Prediction 1 was partially supported, while prediction 2 was met.

Evaluating Differences In Household Subsistence Harvest Patterns Between The Ambler Project And Non-Project Zones, Mouhcine Guettabi, Joshua Greenberg, Joseph Little, Kyle Joly

ISER Reports

Western Alaska is one of largest inhabited, roadless areas in North America and, indeed, the world. Access, via a new road that would transverse Gates of the Arctic National Park and Preserve (GAAR), to a mining district in a vast roadless section of northwest Alaska has been proposed. Given the potential effects of the road on nearby communities, we analyzed how communities connected to the road system compare to their unconnected counterparts. Specifically, using zero inflated negative binomial models, we analyzed subsistence harvest data to understand factors that influence subsistence production at the household level. We found substantial difference in …